-- dump date 20140620_010315 -- class Genbank::CDS -- table cds_note -- id note YP_001265362.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001265363.1 binds the polymerase to DNA and acts as a sliding clamp YP_001265364.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001265365.1 negatively supercoils closed circular double-stranded DNA YP_001265367.1 PFAM: Integrase, catalytic region YP_001265368.1 SMART: AAA ATPase YP_001265372.1 PFAM: protein of unknown function DUF411 YP_001265374.1 PFAM: copper resistance B precursor YP_001265376.1 TIGRFAM: copper-resistance protein, CopA family; PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3 YP_001265378.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001265379.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001265381.1 PFAM: outer membrane efflux protein YP_001265382.1 TIGRFAM: efflux transporter, RND family, MFP subunit YP_001265383.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein YP_001265388.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein YP_001265389.1 PFAM: Heavy metal transport/detoxification protein YP_001265390.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; YHS domain protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein YP_001265398.1 PFAM: sulfatase; protein of unknown function DUF1705 YP_001265399.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001265402.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001265403.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001265406.1 PFAM: glycosyl transferase, family 39 YP_001265407.1 PFAM: glycosyl transferase, family 2 YP_001265408.1 PFAM: GtrA family protein YP_001265409.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001265410.1 PFAM: phosphate-selective porin O and P YP_001265414.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001265416.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein YP_001265417.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001265418.1 PFAM: outer membrane efflux protein YP_001265419.1 PFAM: outer membrane porin YP_001265420.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001265426.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; PAS fold-4 domain protein; SMART: AAA ATPase YP_001265427.1 PFAM: beta-lactamase domain protein YP_001265428.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001265429.1 PFAM: protein of unknown function DUF81 YP_001265430.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001265431.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase YP_001265432.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001265433.1 PFAM: phospholipid/glycerol acyltransferase YP_001265434.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001265435.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001265436.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001265437.1 TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001265438.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001265439.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_001265440.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001265441.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44 YP_001265442.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001265443.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001265444.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein YP_001265445.1 PFAM: SUA5/yciO/yrdC, N-terminal domain YP_001265447.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001265448.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001265449.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001265450.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter YP_001265451.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001265452.1 PFAM: sulfatase YP_001265453.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001265455.1 PFAM: Dopa 4,5-dioxygenase YP_001265456.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001265457.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001265458.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001265459.1 PFAM: protein of unknown function DUF883, ElaB YP_001265460.1 PFAM: protein of unknown function DUF1458 YP_001265461.1 PFAM: protein of unknown function DUF1161 YP_001265462.1 PFAM: luciferase family protein YP_001265463.1 PFAM: OsmC family protein YP_001265464.1 PFAM: protein of unknown function DUF1161 YP_001265468.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001265470.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F YP_001265472.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F YP_001265473.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001265474.1 PFAM: carbonic anhydrase YP_001265475.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter YP_001265478.1 TIGRFAM: Cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase, subunit II; cytochrome c, class I; cytochrome C oxidase subunit II, transmembrane region YP_001265479.1 TIGRFAM: Cytochrome c oxidase, subunit I bacterial type; PFAM: cytochrome c oxidase, subunit I YP_001265480.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001265481.1 PFAM: cytochrome c oxidase, subunit III YP_001265485.1 PFAM: cytochrome oxidase assembly YP_001265486.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001265487.1 PFAM: electron transport protein SCO1/SenC YP_001265488.1 PFAM: NLPA lipoprotein YP_001265489.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001265490.1 part of the metNIQ transport system for methionine YP_001265491.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_001265493.1 PFAM: ABC-3 protein YP_001265494.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001265496.1 PFAM: periplasmic solute binding protein YP_001265497.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_001265499.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001265500.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001265502.1 PFAM: cytochrome c, class I YP_001265503.1 PFAM: DSBA oxidoreductase YP_001265504.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001265505.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001265506.1 PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase, family 2 YP_001265507.1 PFAM: EAL domain protein YP_001265508.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001265509.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001265510.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria YP_001265512.1 PFAM: protein of unknown function DUF1328 YP_001265513.1 PFAM: Inhibitor of vertebrate lysozyme YP_001265514.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system YP_001265515.1 PFAM: nucleoside recognition domain protein YP_001265517.1 PFAM: Mammalian cell entry related domain protein YP_001265518.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001265519.1 PFAM: protein of unknown function DUF140 YP_001265521.1 PFAM: peptidase M16 domain protein YP_001265522.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Pi-cotransporter YP_001265523.1 PFAM: Integral membrane protein TerC YP_001265524.1 TIGRFAM: citrate/H+ symporter, CitMHS family; PFAM: C4-dicarboxylate anaerobic carrier; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001265525.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001265527.1 TIGRFAM: conserverd hypothetical protein YP_001265528.1 TIGRFAM: conserverd hypothetical protein YP_001265529.1 TIGRFAM: conserverd hypothetical protein YP_001265531.1 PFAM: acetyl-CoA hydrolase/transferase YP_001265532.1 PFAM: NAD(P) transhydrogenase, beta subunit YP_001265534.1 PFAM: alanine dehydrogenase/PNT domain protein YP_001265535.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001265536.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001265537.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001265538.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001265539.1 PFAM: FecR protein YP_001265540.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001265541.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001265543.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein YP_001265544.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein YP_001265545.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001265547.1 TIGRFAM: conserved repeat domain; PFAM: Hemolysin-type calcium-binding region; von Willebrand factor, type A; Two component regulator propeller; SMART: Pyrrolo-quinoline quinone YP_001265549.1 PFAM: Taurine catabolism dioxygenase TauD/TfdA YP_001265551.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001265552.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001265554.1 PFAM: Sel1 domain protein repeat-containing protein YP_001265555.1 PFAM: regulatory protein, MarR YP_001265556.1 PFAM: Fusaric acid resistance protein conserved region YP_001265557.1 PFAM: protein of unknown function DUF1656 YP_001265558.1 PFAM: secretion protein HlyD family protein YP_001265559.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001265561.1 PFAM: cytochrome c, class I; iron permease FTR1 YP_001265564.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001265565.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001265566.1 PFAM: response regulator receiver; LytTr DNA-binding region YP_001265567.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001265568.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane YP_001265569.1 PFAM: protein of unknown function DUF513, hemX YP_001265570.1 PFAM: HemY domain protein YP_001265571.1 PFAM: Disulphide bond formation protein DsbB YP_001265572.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001265573.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001265576.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001265578.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001265579.1 PFAM: band 7 protein YP_001265580.1 PFAM: protein of unknown function DUF107 YP_001265581.1 PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001265584.1 PFAM: CBS domain containing protein YP_001265585.1 TIGRFAM: dipeptidase, putative; PFAM: peptidase M20 YP_001265586.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_001265587.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001265588.1 PFAM: response regulator receiver; Metal-dependent hydrolase HDOD YP_001265589.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001265590.1 PFAM: fatty acid desaturase YP_001265591.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001265592.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001265593.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001265594.1 PFAM: NLPA lipoprotein YP_001265596.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001265597.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001265598.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001265599.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001265600.1 PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor YP_001265602.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter YP_001265603.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_001265604.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001265605.1 Part of the ABC transporter complex tauABC involved in taurine import YP_001265606.1 TIGRFAM: taurine ABC transporter, periplasmic binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; NMT1/THI5 like; SMART: extracellular solute-binding protein, family 3 YP_001265607.1 PFAM: outer membrane porin YP_001265608.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001265609.1 PFAM: NADPH-dependent FMN reductase YP_001265610.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SMART: extracellular solute-binding protein, family 3 YP_001265611.1 catalyzes the release of sulfite from alkanesulfonates YP_001265612.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001265613.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_001265614.1 PFAM: TOBE domain protein YP_001265615.1 PFAM: regulatory protein, TetR YP_001265616.1 involved in the first step of glutathione biosynthesis YP_001265617.1 PFAM: thioesterase superfamily protein YP_001265618.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold YP_001265619.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001265620.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001265621.1 TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp YP_001265622.1 PFAM: protein of unknown function DUF785 YP_001265623.1 PFAM: RNA-binding S4 domain protein YP_001265624.1 PFAM: phosphoesterase, PA-phosphatase related YP_001265625.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001265626.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001265627.1 PFAM: thioesterase superfamily protein YP_001265628.1 PFAM: 17 kDa surface antigen YP_001265629.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001265630.1 TIGRFAM: formate dehydrogenase family accessory protein FdhD; PFAM: formate dehydrogenase, subunit FdhD YP_001265631.1 PFAM: Peptidoglycan-binding LysM; transport-associated YP_001265632.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001265633.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001265634.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase YP_001265635.1 TIGRFAM: thioesterase domain, putative YP_001265636.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001265637.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001265638.1 TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001265639.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_001265641.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001265642.1 PFAM: outer membrane porin YP_001265643.1 PFAM: ferredoxin-dependent glutamate synthase YP_001265644.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001265645.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001265646.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001265649.1 SMART: helix-turn-helix domain protein YP_001265650.1 PFAM: protein of unknown function DUF891 YP_001265655.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001265656.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001265657.1 PFAM: extracellular solute-binding protein, family 3 YP_001265658.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001265659.1 TIGRFAM: GABA permease; PFAM: amino acid permease-associated region YP_001265661.1 PFAM: protein of unknown function DUF344 YP_001265662.1 PFAM: Fe(II) trafficking protein YggX YP_001265663.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein YP_001265664.1 PFAM: AsmA family protein YP_001265665.1 PFAM: major facilitator superfamily MFS_1 YP_001265666.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001265667.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001265669.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001265670.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001265671.1 TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001265672.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001265673.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001265674.1 TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001265675.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001265677.1 PFAM: Ricin B lectin YP_001265679.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001265680.1 PFAM: protein of unknown function DUF849 YP_001265681.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001265682.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001265685.1 PFAM: protein of unknown function DUF1311 YP_001265686.1 PFAM: peptidase M19, renal dipeptidase YP_001265688.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001265689.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001265690.1 PFAM: Electron transfer flavoprotein, alpha/beta-subunit-like; Electron transfer flavoprotein, alpha subunit-like YP_001265691.1 PFAM: Electron transfer flavoprotein, alpha/beta-subunit-like YP_001265693.1 PFAM: Rieske [2Fe-2S] domain protein YP_001265694.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001265696.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001265698.1 PFAM: protein of unknown function DUF710 YP_001265699.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001265700.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001265701.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001265702.1 TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase YP_001265703.1 TIGRFAM: sarcosine oxidase, delta subunit family; PFAM: Sarcosine oxidase, delta subunit, heterotetrameric YP_001265704.1 TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001265705.1 TIGRFAM: sarcosine oxidase, gamma subunit family; PFAM: Sarcosine oxidase, gamma subunit YP_001265706.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001265707.1 TIGRFAM: Formaldehyde dehydrogenase, glutathione-independent; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001265712.1 PFAM: phospholipid/glycerol acyltransferase YP_001265713.1 PFAM: protein of unknown function DUF785 YP_001265714.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_001265715.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_001265716.1 PFAM: Inner membrane CreD family protein YP_001265717.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001265718.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001265719.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001265720.1 TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001265721.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001265722.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001265723.1 TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase, family 9 YP_001265724.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase, family 9 YP_001265725.1 PFAM: glycosyl transferase, group 1 YP_001265726.1 PFAM: lipopolysaccharide kinase YP_001265727.1 PFAM: lipopolysaccharide kinase YP_001265728.1 PFAM: lipopolysaccharide kinase YP_001265732.1 PFAM: PepSY-associated TM helix domain protein YP_001265733.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001265734.1 PFAM: FecR protein YP_001265735.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in P. aeruginosa this sigma factor regulates the production of the ferrichrome outer membrane receptor FiuA. YP_001265736.1 TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001265737.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative YP_001265738.1 PFAM: response regulator receiver YP_001265739.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001265740.1 PFAM: amino acid-binding ACT domain protein YP_001265741.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane YP_001265742.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001265743.1 TIGRFAM: molybdate transport repressor, ModE; PFAM: regulatory protein, LysR; TOBE domain protein YP_001265745.1 TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001265746.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001265747.1 PFAM: alpha/beta hydrolase fold YP_001265748.1 TIGRFAM: biotin biosynthesis protein BioC; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001265749.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001265751.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001265752.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001265753.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001265754.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001265755.1 PFAM: aminotransferase class-III YP_001265756.1 PFAM: protein of unknown function UPF0057 YP_001265757.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein YP_001265758.1 TIGRFAM: coenzyme PQQ biosynthesis protein E; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001265759.1 with PqqC converts a biosynthetic intermediate to pyrroloquinoline quinone YP_001265760.1 Required in the synthesis of PPQ, but its exact function is unknown YP_001265761.1 possibly involved in transport of pyrroloquinoline quinone transport YP_001265762.1 TIGRFAM: coenzyme PQQ biosynthesis protein PqqF; PFAM: peptidase M16 domain protein YP_001265763.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001265764.1 PFAM: amine oxidase YP_001265765.1 PFAM: regulatory protein, AsnC/Lrp family YP_001265769.1 PFAM: protein of unknown function DUF955 YP_001265772.1 PFAM: Integrase, catalytic region YP_001265773.1 PFAM: transposase IS3/IS911 family protein YP_001265774.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; extracellular solute-binding protein, family 3; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001265775.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001265776.1 synthesizes RNA primers at the replication forks YP_001265777.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001265778.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001265779.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001265780.1 TIGRFAM: dihydroneopterin aldolase YP_001265781.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001265782.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_001265783.1 PFAM: SpoVR family protein YP_001265784.1 PFAM: protein of unknown function DUF444 YP_001265785.1 PFAM: PrkA serine kinase; PrkA AAA domain protein YP_001265786.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_001265787.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001265788.1 protein associated with Co2+ and Mg2+ efflux YP_001265789.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001265790.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001265791.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA N-terminal domain YP_001265792.1 PFAM: OstA family protein; Organic solvent tolerance protein YP_001265793.1 PFAM: aminoglycoside phosphotransferase YP_001265794.1 PFAM: Nucleotidyl transferase YP_001265795.1 PFAM: heat shock protein DnaJ domain protein YP_001265797.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; extracellular solute-binding protein, family 3 YP_001265798.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001265799.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001265800.1 PFAM: extracellular solute-binding protein, family 1 YP_001265801.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001265802.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001265803.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001265804.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001265805.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001265806.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: lipolytic enzyme, G-D-S-L family; Autotransporter beta- domain protein YP_001265807.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001265808.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001265809.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001265811.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001265812.1 PFAM: OsmC family protein YP_001265815.1 PFAM: histidine triad (HIT) protein YP_001265816.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001265817.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001265818.1 PFAM: conserved hypothetical protein 701 YP_001265819.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001265820.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001265821.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001265822.1 PFAM: peptidase M23B; Opacity-associated protein A; Opacity-associated protein A, N-terminal domain protein YP_001265823.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001265824.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001265825.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001265827.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001265828.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001265829.1 Modulates Rho-dependent transcription termination YP_001265830.1 binds directly to 23S ribosomal RNA YP_001265831.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001265832.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001265833.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001265834.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001265835.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001265836.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001265837.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001265838.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001265839.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001265840.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001265841.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001265842.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001265843.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001265844.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001265845.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001265846.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001265847.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001265848.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001265849.1 one of the stabilizing components for the large ribosomal subunit YP_001265850.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001265851.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001265852.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001265853.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001265854.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001265855.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001265856.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001265857.1 binds 5S rRNA along with protein L5 and L25 YP_001265858.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001265859.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001265860.1 late assembly protein YP_001265861.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001265862.1 PFAM: ribosomal protein L36 YP_001265863.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001265864.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001265865.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001265866.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001265867.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001265868.1 PFAM: Catalase domain protein YP_001265869.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein YP_001265870.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001265871.1 PFAM: major facilitator superfamily MFS_1 YP_001265872.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_001265873.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001265874.1 PFAM: protein of unknown function DUF81 YP_001265875.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001265876.1 PFAM: molybdopterin oxidoreductase Fe4S4 region YP_001265877.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001265878.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Formate dehydrogenase, transmembrane YP_001265879.1 TIGRFAM: formate dehydrogenase, gamma subunit YP_001265880.1 TIGRFAM: formate dehydrogenase accessory protein FdhE; PFAM: formate dehydrogenase accessory protein YP_001265881.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001265882.1 TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; Elongation factor SelB, winged helix 2; Elongation factor SelB, winged helix 3 YP_001265883.1 PFAM: Asparaginase/glutaminase YP_001265884.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter YP_001265887.1 PFAM: dTDP-4-dehydrorhamnose reductase YP_001265888.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility C-terminal domain; KR YP_001265889.1 PFAM: helix-turn-helix, HxlR type YP_001265890.1 PFAM: major facilitator superfamily MFS_1 YP_001265891.1 PFAM: OmpW family protein YP_001265893.1 PFAM: protein of unknown function DUF214 YP_001265894.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001265897.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001265898.1 PFAM: methyltransferase small; Methyltransferase type 12 YP_001265900.1 PFAM: ATP-cone domain protein YP_001265901.1 TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_001265902.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001265903.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis YP_001265904.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001265905.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001265906.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001265907.1 PFAM: phosphatidylglycerophosphatase A YP_001265909.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001265911.1 PFAM: periplasmic binding protein YP_001265912.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001265913.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001265914.1 PFAM: Polyprenyl synthetase YP_001265915.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001265916.1 DHBP synthase; functions during riboflavin biosynthesis YP_001265917.1 PFAM: Zeta toxin family protein YP_001265918.1 PFAM: putative esterase YP_001265919.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001265920.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001265921.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001265922.1 PFAM: Hemerythrin HHE cation binding domain protein YP_001265925.1 PFAM: copper resistance B precursor YP_001265926.1 TIGRFAM: copper-resistance protein, CopA family; PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3 YP_001265929.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001265930.1 PFAM: protein of unknown function DUF980 YP_001265931.1 PFAM: SNARE associated Golgi protein YP_001265932.1 PFAM: GCN5-related N-acetyltransferase YP_001265933.1 catalyzes the formation of acetaldehyde from ethanolamine YP_001265934.1 PFAM: Ethanolamine ammonia lyase large subunit YP_001265935.1 TIGRFAM: ethanolamine transproter; PFAM: amino acid permease-associated region YP_001265936.1 PFAM: aldehyde dehydrogenase YP_001265937.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001265938.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001265939.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein YP_001265940.1 PFAM: protein of unknown function DUF1375 YP_001265942.1 PFAM: MORN repeat-containing protein YP_001265943.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001265944.1 PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein YP_001265945.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001265946.1 PFAM: dehydrogenase, E1 component YP_001265947.1 PFAM: ATP-NAD/AcoX kinase YP_001265948.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase YP_001265949.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001265950.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001265951.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001265952.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001265953.1 PFAM: chemotaxis sensory transducer YP_001265954.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver YP_001265956.1 PFAM: NUDIX hydrolase YP_001265957.1 PFAM: translation initiation factor SUI1 YP_001265958.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001265959.1 PFAM: protein of unknown function DUF1568 YP_001265960.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE YP_001265961.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2 YP_001265963.1 penicillin-insensitive transglycosylase/transpeptidase YP_001265964.1 PFAM: Polypeptide-transport-associated domain protein, ShlB-type YP_001265965.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001265966.1 PFAM: peptidase A24A, prepilin type IV YP_001265969.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001265971.1 PFAM: MaoC domain protein dehydratase YP_001265972.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001265973.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001265974.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001265975.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer YP_001265976.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding YP_001265977.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein YP_001265979.1 PFAM: Heavy metal transport/detoxification protein YP_001265980.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001265982.1 SMART: regulatory protein, ArsR YP_001265983.1 catalyzes the formation of inosine from adenosine YP_001265984.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001265985.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949 YP_001265986.1 PFAM: regulatory protein, TetR; Tetracycline transcriptional regulator YcdC, C-terminal domain protein YP_001265987.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001265988.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001265989.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001265990.1 PFAM: Paraquat-inducible protein A YP_001265991.1 PFAM: Paraquat-inducible protein A YP_001265992.1 PFAM: Mammalian cell entry related domain protein YP_001265993.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001265994.1 TIGRFAM: integral membrane protein MviN; PFAM: polysaccharide biosynthesis protein; virulence factor MVIN family protein YP_001265995.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001265996.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001265997.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001265998.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001265999.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001266004.1 PFAM: FAD dependent oxidoreductase YP_001266005.1 PFAM: Amidase YP_001266006.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001266007.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001266008.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001266009.1 PFAM: inner-membrane translocator YP_001266010.1 PFAM: inner-membrane translocator YP_001266012.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001266015.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001266016.1 PFAM: protein of unknown function DUF152 YP_001266017.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001266018.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001266020.1 PFAM: Protein of unknown function DUF1780 YP_001266023.1 PFAM: protein of unknown function DUF329 YP_001266024.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001266025.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein YP_001266026.1 PFAM: type II secretion system protein YP_001266027.1 PFAM: Fimbrial protein pilin YP_001266028.1 PFAM: filamentation induced by cAMP protein Fic YP_001266034.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter YP_001266036.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001266038.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001266039.1 PFAM: extracellular solute-binding protein, family 3 YP_001266040.1 PFAM: homocysteine S-methyltransferase YP_001266041.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_001266042.1 PFAM: amino acid permease-associated region YP_001266043.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266044.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001266045.1 PFAM: regulatory protein, AsnC/Lrp family YP_001266046.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001266047.1 PFAM: aldehyde dehydrogenase YP_001266048.1 PFAM: Endoribonuclease L-PSP YP_001266049.1 PFAM: Bile acid:sodium symporter YP_001266050.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001266051.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001266053.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001266054.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001266055.1 PFAM: transcription elongation factor GreA/GreB domain protein YP_001266061.1 PFAM: Uncharacterized protein UPF0114 YP_001266063.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type YP_001266065.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein-like YP_001266066.1 PFAM: Polyprenyl synthetase YP_001266068.1 PFAM: ribosomal protein L21 YP_001266069.1 involved in the peptidyltransferase reaction during translation YP_001266070.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001266071.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001266072.1 PFAM: CreA family protein YP_001266077.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase YP_001266078.1 PFAM: Peptidase M15A YP_001266079.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266080.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001266081.1 PFAM: FecR protein YP_001266082.1 PFAM: major facilitator superfamily MFS_1 YP_001266083.1 PFAM: major facilitator superfamily MFS_1 YP_001266084.1 PFAM: FecR protein YP_001266085.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001266086.1 PFAM: HhH-GPD family protein YP_001266087.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding YP_001266088.1 PFAM: MscS Mechanosensitive ion channel YP_001266089.1 PFAM: Egg lysin (Sperm-lysin) YP_001266090.1 PFAM: aldehyde dehydrogenase YP_001266091.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001266093.1 PFAM: isochorismatase hydrolase YP_001266094.1 PFAM: protein of unknown function DUF344 YP_001266095.1 TIGRFAM: potassium efflux system protein; PFAM: sodium/hydrogen exchanger YP_001266096.1 PFAM: protein of unknown function UPF0118 YP_001266097.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001266098.1 PFAM: secretion protein HlyD family protein YP_001266100.1 TIGRFAM: sulfate transporter; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter YP_001266101.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001266102.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001266103.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001266104.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001266105.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001266106.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001266107.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001266108.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001266109.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001266110.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12 YP_001266111.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001266112.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001266115.1 PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein YP_001266116.1 PFAM: regulatory protein, MerR YP_001266117.1 PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722 YP_001266119.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility C-terminal domain; domain of unknown function DUF1731 YP_001266120.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001266121.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease YP_001266122.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001266123.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively YP_001266127.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001266131.1 PFAM: phospholipid/glycerol acyltransferase YP_001266134.1 PFAM: protein of unknown function DUF159 YP_001266135.1 PFAM: peptidase M48, Ste24p YP_001266136.1 PFAM: protein of unknown function UPF0016 YP_001266137.1 PFAM: methyltransferase small; Methyltransferase type 12; Methyltransferase small, N-terminal domain protein YP_001266138.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor YP_001266139.1 activates fatty acids by binding to coenzyme A YP_001266140.1 PFAM: protein of unknown function DUF1302 YP_001266141.1 PFAM: protein of unknown function DUF1329 YP_001266142.1 PFAM: regulatory protein, LuxR; Tetratricopeptide TPR_4 YP_001266143.1 PFAM: TPR repeat-containing protein; response regulator receiver; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001266144.1 PFAM: ATP-binding region, ATPase domain protein domain protein YP_001266145.1 PFAM: beta-lactamase domain protein YP_001266146.1 PFAM: OmpA/MotB domain protein YP_001266147.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001266149.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001266150.1 PFAM: glutathione peroxidase YP_001266151.1 PFAM: glycosyl transferase, group 1 YP_001266152.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAC repeat-containing protein YP_001266154.1 PFAM: GAD-like; Domain of unknown function DUF1851 YP_001266155.1 putative role in sulfur assimilation YP_001266156.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001266157.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001266158.1 PFAM: protein of unknown function DUF1631 YP_001266159.1 PFAM: N-acetylmuramoyl-L-alanine amidase, family 2 YP_001266161.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease YP_001266162.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_001266163.1 TIGRFAM: phosphocarrier, HPr family; phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing enzyme; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein YP_001266164.1 PFAM: PfkB domain protein YP_001266165.1 TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit YP_001266168.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001266169.1 PFAM: outer membrane porin YP_001266171.1 PFAM: protein of unknown function UPF0153 YP_001266173.1 PFAM: response regulator receiver; CheW domain protein YP_001266174.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein YP_001266175.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001266176.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein YP_001266177.1 PFAM: YLP motif domain protein; glycoprotein YP_001266178.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001266179.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001266180.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001266181.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase, subunit II; COX aromatic rich domain protein YP_001266182.1 TIGRFAM: Cytochrome o ubiquinol oxidase, subunit I; PFAM: cytochrome c oxidase, subunit I YP_001266183.1 TIGRFAM: Cytochrome o ubiquinol oxidase, subunit III; PFAM: cytochrome c oxidase, subunit III YP_001266184.1 TIGRFAM: Cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV YP_001266185.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001266186.1 PFAM: aminotransferase, class I and II YP_001266188.1 PFAM: protein of unknown function UPF0153 YP_001266189.1 PFAM: GCN5-related N-acetyltransferase YP_001266190.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001266191.1 PFAM: FecR protein YP_001266192.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001266194.1 PFAM: protein of unknown function DUF1311 YP_001266195.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001266196.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001266197.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001266198.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001266199.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001266200.1 PFAM: protein of unknown function UPF0187 YP_001266201.1 TIGRFAM: Addiction module killer protein, HI1419; PFAM: protein of unknown function DUF891 YP_001266202.1 TIGRFAM: Addiction module antidote protein, HI1420 YP_001266203.1 PFAM: GCN5-related N-acetyltransferase YP_001266205.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001266206.1 PFAM: FAD dependent oxidoreductase YP_001266207.1 PFAM: Endoribonuclease L-PSP YP_001266208.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001266209.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001266210.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001266211.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001266212.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001266213.1 PFAM: 17 kDa surface antigen YP_001266214.1 PFAM: inositol monophosphatase YP_001266215.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001266216.1 TIGRFAM: serine O-acetyltransferase YP_001266217.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074 YP_001266218.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001266219.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein YP_001266220.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein YP_001266221.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001266222.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001266223.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin YP_001266224.1 PFAM: protein of unknown function DUF528 YP_001266225.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001266226.1 TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM domain protein YP_001266227.1 TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001266228.1 SMART: helix-turn-helix domain protein YP_001266229.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001266230.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001266232.1 PFAM: Pyrrolo-quinoline quinone YP_001266233.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001266234.1 catalyzes the transfer of an amino moiety YP_001266235.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001266236.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase YP_001266237.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001266238.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit YP_001266239.1 PFAM: Sel1 domain protein repeat-containing protein YP_001266240.1 PFAM: Orn/DAP/Arg decarboxylase 2 YP_001266241.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001266242.1 PFAM: FecR protein YP_001266243.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001266244.1 TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_001266245.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001266246.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001266247.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001266248.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001266249.1 PFAM: extracellular solute-binding protein, family 1 YP_001266250.1 PFAM: protein of unknown function DUF861, cupin_3 YP_001266251.1 PFAM: FAD dependent oxidoreductase YP_001266252.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001266254.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001266258.1 PFAM: sodium/hydrogen exchanger YP_001266259.1 PFAM: protein of unknown function DUF6, transmembrane YP_001266260.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266261.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001266262.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001266263.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001266264.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001266265.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001266266.1 PFAM: extracellular solute-binding protein, family 5 YP_001266267.1 PFAM: outer membrane porin YP_001266268.1 PFAM: extracellular solute-binding protein, family 5 YP_001266269.1 PFAM: extracellular solute-binding protein, family 5 YP_001266270.1 PFAM: protein of unknown function DUF541 YP_001266271.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001266272.1 PFAM: response regulator receiver; helix-turn-helix, Fis-type YP_001266273.1 PFAM: beta-lactamase YP_001266275.1 PFAM: YceI family protein YP_001266277.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein YP_001266278.1 PFAM: protein of unknown function DUF1486 YP_001266280.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001266281.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region YP_001266283.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001266285.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001266286.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001266287.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001266288.1 PFAM: lipopolysaccharide kinase YP_001266290.1 MexW; inner membrane protein; member of RND (resistance, nodulation, and division) family; involved in resistance to fluoroquinolones, tetracycline, chloramphenicol, erythromycin, ethidium bromide, and acriflavine; functions along with MexV and OprM YP_001266291.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001266292.1 PFAM: uncharacterised conserved protein UCP028101 YP_001266294.1 PFAM: protein of unknown function DUF1111 YP_001266298.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001266299.1 PFAM: manganese and iron superoxide dismutase YP_001266300.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001266301.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001266302.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001266304.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001266305.1 PFAM: regulatory protein, ArsR YP_001266306.1 PFAM: protein of unknown function DUF479 YP_001266307.1 PFAM: phospholipid/glycerol acyltransferase YP_001266311.1 PFAM: Auxin Efflux Carrier YP_001266312.1 PFAM: amino acid permease-associated region YP_001266313.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region YP_001266314.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A YP_001266315.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001266316.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001266317.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001266318.1 functions in MreBCD complex in some organisms YP_001266319.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001266320.1 PFAM: Rod shape-determining protein MreD YP_001266321.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001266322.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein YP_001266324.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001266325.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001266326.1 PFAM: protein of unknown function DUF615 YP_001266327.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001266329.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001266330.1 PFAM: manganese and iron superoxide dismutase YP_001266331.1 PFAM: zinc/iron permease YP_001266332.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein YP_001266333.1 PFAM: uncharacterised P-loop ATPase protein UPF0042 YP_001266334.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_001266335.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA YP_001266336.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001266337.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001266338.1 TIGRFAM: Cell envelope biogenesis YhbN; PFAM: OstA family protein YP_001266339.1 PFAM: protein of unknown function DUF1239 YP_001266340.1 TIGRFAM: hydrolase, HAD-superfamily, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family YP_001266341.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001266342.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001266343.1 PFAM: protein of unknown function DUF140 YP_001266344.1 PFAM: Mammalian cell entry related domain protein YP_001266345.1 PFAM: toluene tolerance family protein YP_001266347.1 PFAM: BolA family protein YP_001266348.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001266349.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001266350.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001266351.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001266353.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001266354.1 TIGRFAM: cyanate transporter; PFAM: major facilitator superfamily MFS_1 YP_001266356.1 PFAM: Excinuclease ABC, C subunit domain protein YP_001266357.1 PFAM: 37kDa nucleoid-associated protein YP_001266358.1 PFAM: histone family protein DNA-binding protein YP_001266359.1 PFAM: protein of unknown function DUF890 YP_001266360.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001266362.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001266363.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001266364.1 PFAM: permease YjgP/YjgQ family protein YP_001266365.1 PFAM: permease YjgP/YjgQ family protein YP_001266366.1 PFAM: RDD domain containing protein YP_001266367.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001266368.1 TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel YP_001266369.1 TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001266370.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001266371.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001266372.1 PFAM: DoxX family protein YP_001266374.1 PFAM: protein of unknown function DUF692 YP_001266376.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001266377.1 PFAM: protein of unknown function DUF1109 YP_001266378.1 PFAM: sodium/glutamate symporter YP_001266379.1 PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: AAA ATPase YP_001266381.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001266382.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_001266383.1 catalyzes the degradation of arginine to citruline and ammonia YP_001266384.1 TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region YP_001266385.1 TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region YP_001266386.1 PFAM: protein of unknown function DUF454 YP_001266387.1 PFAM: Haem oxygenase YP_001266388.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001266389.1 PFAM: FecR protein YP_001266390.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001266391.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001266392.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001266393.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001266394.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001266395.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001266396.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001266397.1 PFAM: N-acylglucosamine 2-epimerase YP_001266398.1 PFAM: extracellular solute-binding protein, family 1 YP_001266399.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001266400.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001266401.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001266402.1 PFAM: Carbohydrate-selective porin OprB YP_001266403.1 PFAM: Aldose 1-epimerase YP_001266404.1 Represses the expression of the zwf, eda, glp and gap YP_001266405.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001266406.1 TIGRFAM: 6-phosphogluconolactonase YP_001266407.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001266410.1 TIGRFAM: 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain YP_001266411.1 PFAM: peptidase M23B YP_001266412.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001266413.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266414.1 PFAM: protein of unknown function DUF81 YP_001266416.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001266417.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001266418.1 PFAM: ADP-ribosylation/Crystallin J1 YP_001266420.1 PFAM: multicopper oxidase, type 2; multicopper oxidase, type 3 YP_001266421.1 PFAM: CMP/dCMP deaminase, zinc-binding YP_001266422.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001266423.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001266425.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase YP_001266426.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106 YP_001266427.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106 YP_001266428.1 PFAM: General secretion pathway protein K YP_001266429.1 PFAM: protein of unknown function DUF839 YP_001266432.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein YP_001266433.1 PFAM: type II secretion system protein E YP_001266434.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein YP_001266435.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G YP_001266436.1 TIGRFAM: general secretion pathway protein H YP_001266437.1 PFAM: type II secretion system protein I/J YP_001266439.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L YP_001266442.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein YP_001266443.1 PFAM: transcriptional regulator PadR family protein YP_001266445.1 PFAM: amino acid permease-associated region YP_001266446.1 PFAM: ferredoxin-dependent glutamate synthase YP_001266447.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like YP_001266448.1 PFAM: NUDIX hydrolase YP_001266449.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266450.1 PFAM: alpha/beta hydrolase fold YP_001266451.1 PFAM: GlpM family protein YP_001266452.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001266453.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001266454.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001266455.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001266456.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001266457.1 PFAM: extracellular solute-binding protein, family 3 YP_001266458.1 PFAM: leucine-rich repeat protein; SMART: leucine-rich repeat-containing protein, typical subtype YP_001266459.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001266460.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein YP_001266461.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001266462.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein YP_001266463.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region YP_001266464.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001266465.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001266466.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001266467.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin YP_001266468.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein YP_001266469.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein YP_001266470.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001266471.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001266472.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001266473.1 PFAM: OmpA/MotB domain protein YP_001266474.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001266476.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001266478.1 TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001266479.1 TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; PFAM: FMN-binding domain protein YP_001266480.1 TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2 and RnfD family protein YP_001266482.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001266483.1 PFAM: protein of unknown function DUF59 YP_001266484.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001266485.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001266488.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like YP_001266489.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase YP_001266490.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA YP_001266492.1 PFAM: peptidase S45, penicillin amidase YP_001266493.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001266495.1 related to alanyl-tRNA synthetase HxxxH domain YP_001266496.1 PFAM: major facilitator superfamily MFS_1 YP_001266497.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001266498.1 PFAM: SEC-C motif domain protein YP_001266499.1 SMART: Water Stress and Hypersensitive response YP_001266500.1 PFAM: SEC-C motif domain protein YP_001266502.1 PFAM: OmpA/MotB domain protein YP_001266503.1 PFAM: OmpA/MotB domain protein YP_001266504.1 PFAM: protein of unknown function DUF1145 YP_001266506.1 helicase involved in DNA repair and perhaps also replication YP_001266508.1 PFAM: beta-lactamase YP_001266509.1 PFAM: OmpA/MotB domain protein YP_001266510.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001266512.1 PFAM: 17 kDa surface antigen YP_001266513.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001266514.1 PFAM: FAD dependent oxidoreductase YP_001266516.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001266517.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001266518.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001266519.1 PFAM: inner-membrane translocator YP_001266520.1 PFAM: Extracellular ligand-binding receptor YP_001266522.1 PFAM: 6-phosphogluconate dehydrogenase, NAD-binding YP_001266523.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MHYT domain protein YP_001266524.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001266529.1 PFAM: Fusaric acid resistance protein conserved region YP_001266530.1 PFAM: protein of unknown function DUF1656 YP_001266531.1 PFAM: secretion protein HlyD family protein YP_001266533.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; CHASE4 domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001266534.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; MASE2 domain protein YP_001266536.1 catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis YP_001266537.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001266539.1 PFAM: Asparaginase/glutaminase YP_001266540.1 TIGRFAM: yecA family protein YP_001266541.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain YP_001266542.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001266543.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266544.1 PFAM: Aldose 1-epimerase YP_001266545.1 PFAM: protein of unknown function DUF6, transmembrane YP_001266546.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit YP_001266547.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component YP_001266548.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit YP_001266549.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein YP_001266550.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001266551.1 PFAM: outer membrane porin YP_001266552.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor YP_001266553.1 PFAM: plasmid stabilization system YP_001266554.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001266555.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001266556.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001266557.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001266558.1 PFAM: 4'-phosphopantetheinyl transferase YP_001266559.1 PFAM: dienelactone hydrolase YP_001266561.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001266562.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001266563.1 involved in the transport of C4-dicarboxylates across the membrane YP_001266565.1 PFAM: protein of unknown function UPF0066 YP_001266566.1 PFAM: protein of unknown function DUF1456 YP_001266567.1 PFAM: RNA-binding S4 domain protein YP_001266568.1 PFAM: GCN5-related N-acetyltransferase YP_001266573.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001266574.1 PFAM: K+ potassium transporter YP_001266575.1 PFAM: virulence factor family protein YP_001266576.1 PFAM: protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472 YP_001266577.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001266579.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001266580.1 PFAM: outer membrane porin YP_001266581.1 PFAM: histidine triad (HIT) protein YP_001266582.1 PFAM: SlyX family protein YP_001266583.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001266584.1 PFAM: Ferritin, Dps family protein YP_001266586.1 TIGRFAM: putative regulatory protein, FmdB family YP_001266587.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001266588.1 PFAM: protein of unknown function DUF28 YP_001266589.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001266590.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001266591.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001266592.1 TIGRFAM: Pol-Pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein YP_001266593.1 TIGRFAM: Tol-Pal system, TolQ; PFAM: MotA/TolQ/ExbB proton channel YP_001266594.1 TIGRFAM: Biopolymer transport, TolR; PFAM: Biopolymer transport protein ExbD/TolR YP_001266595.1 TIGRFAM: TonB family protein; Tol-Pal system, TolA; PFAM: TolA family protein YP_001266596.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001266597.1 TIGRFAM: Peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein YP_001266598.1 TIGRFAM: Tol-Pal system, YbgF; PFAM: Tetratricopeptide TPR_2 repeat protein YP_001266599.1 PFAM: Radical SAM domain protein YP_001266600.1 TIGRFAM: exsB protein; PFAM: ExsB family protein YP_001266601.1 PFAM: cation efflux protein YP_001266602.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001266603.1 PFAM: amino acid permease-associated region YP_001266604.1 PFAM: protein of unknown function DUF945 YP_001266605.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001266606.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001266607.1 PFAM: peptidase M48, Ste24p YP_001266608.1 PFAM: SirA family protein YP_001266609.1 PFAM: protein of unknown function UPF0118 YP_001266610.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001266612.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001266614.1 PFAM: beta-lactamase domain protein YP_001266615.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001266616.1 TIGRFAM: Addiction module antidote protein, HI1420 YP_001266619.1 PFAM: 17 kDa surface antigen; SH3, type 3 domain protein; SMART: SH3 domain protein domain protein YP_001266622.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001266624.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001266625.1 PFAM: regulatory protein, ArsR YP_001266626.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001266627.1 PFAM: FAD dependent oxidoreductase YP_001266628.1 PFAM: aldehyde dehydrogenase YP_001266629.1 PFAM: dihydrodipicolinate synthetase YP_001266630.1 PFAM: proline racemase YP_001266631.1 PFAM: amino acid permease-associated region YP_001266632.1 PFAM: helix-turn-helix- domain containing protein, AraC type; PAS fold-4 domain protein YP_001266633.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266634.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain YP_001266635.1 PFAM: protein of unknown function UPF0187 YP_001266636.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001266637.1 TIGRFAM: oxidoreductase alpha (molybdopterin) subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001266638.1 PFAM: regulatory protein, AsnC/Lrp family YP_001266639.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001266641.1 PFAM: sulfatase; protein of unknown function DUF1705 YP_001266642.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease YP_001266643.1 PFAM: protein of unknown function DUF709 YP_001266644.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001266645.1 PFAM: nitroreductase YP_001266646.1 PFAM: protein of unknown function UPF0153 YP_001266648.1 PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001266649.1 PFAM: HNH endonuclease; SMART: HNH nuclease YP_001266650.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller YP_001266652.1 PFAM: glutamine amidotransferase, class-II YP_001266654.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266655.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001266656.1 PFAM: LamB/YcsF family protein YP_001266657.1 PFAM: Allophanate hydrolase subunit 1 YP_001266658.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2 YP_001266660.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001266662.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001266663.1 PFAM: Aspartyl/Asparaginyl beta-hydroxylase YP_001266665.1 PFAM: protein of unknown function DUF6, transmembrane YP_001266667.1 PFAM: protein of unknown function DUF6, transmembrane YP_001266668.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_001266670.1 SMART: RNA binding S1 domain protein YP_001266672.1 PFAM: CsbD family protein YP_001266673.1 TIGRFAM: putative ribonuclease BN; PFAM: ribonuclease BN YP_001266674.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001266675.1 PFAM: GCN5-related N-acetyltransferase YP_001266678.1 PFAM: DGPFAETKE family protein YP_001266679.1 PFAM: Activator of Hsp90 ATPase 1 family protein YP_001266680.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Tetratricopeptide TPR_2 repeat protein; Sigma-70, region 4 type 2 YP_001266681.1 PFAM: MaoC domain protein dehydratase YP_001266682.1 PFAM: alpha/beta hydrolase fold YP_001266683.1 Disruption of the fadD2 gene did not have any effect on the catabolism of acetic, butyric and longer fatty acids (aliphatic or aromatic); however, might be involved in the specific activation of other fatty acids and may be functional when FadD1 is inactivated. YP_001266684.1 activates fatty acids by binding to coenzyme A; involved in the beta-oxidation of n-alkanoic and n-phenylalkanoic acids YP_001266685.1 PFAM: FAD dependent oxidoreductase YP_001266686.1 PFAM: glutamine synthetase, catalytic region YP_001266688.1 TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases-like YP_001266689.1 catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001266691.1 PFAM: protein of unknown function DUF482 YP_001266692.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001266693.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001266694.1 PFAM: alpha/beta hydrolase fold YP_001266695.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266697.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase YP_001266698.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6, transmembrane YP_001266699.1 PFAM: transposase, IS4 family protein YP_001266700.1 PFAM: Cupin 2, conserved barrel domain protein YP_001266701.1 PFAM: 6-phosphogluconate dehydrogenase, NAD-binding YP_001266702.1 PFAM: protein of unknown function DUF453 YP_001266703.1 TIGRFAM: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; PFAM: Dimethylmenaquinone methyltransferase YP_001266704.1 PFAM: LmbE family protein YP_001266705.1 PFAM: outer membrane porin YP_001266706.1 PFAM: sodium:dicarboxylate symporter YP_001266707.1 PFAM: amidohydrolase 2 YP_001266708.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266709.1 PFAM: Dimethylmenaquinone methyltransferase YP_001266710.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001266711.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001266712.1 PFAM: regulatory protein, IclR; Transcriptional regulator IclR-like YP_001266715.1 PFAM: transposase IS3/IS911 family protein YP_001266716.1 PFAM: transposase, mutator type YP_001266719.1 PFAM: MscS Mechanosensitive ion channel YP_001266720.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001266722.1 PFAM: protein of unknown function DUF497 YP_001266725.1 PFAM: protein of unknown function DUF6, transmembrane YP_001266726.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1 YP_001266727.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266729.1 PFAM: Na+/solute symporter YP_001266730.1 TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase YP_001266731.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266732.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein YP_001266733.1 PFAM: DTW domain containing protein YP_001266734.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein YP_001266735.1 PFAM: protein of unknown function DUF454 YP_001266736.1 TIGRFAM: yecA family protein YP_001266737.1 TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001266738.1 PFAM: regulatory protein, MarR YP_001266739.1 PFAM: Patatin; surface antigen variable number repeat protein YP_001266740.1 TIGRFAM: conserved hypothetical selenoprotein; PFAM: Selenoprotein W-related YP_001266741.1 PFAM: protein of unknown function DUF6, transmembrane YP_001266742.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001266743.1 PFAM: metallophosphoesterase YP_001266745.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001266746.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter YP_001266747.1 PFAM: nitroreductase YP_001266748.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001266749.1 PFAM: protein of unknown function, Spy-related YP_001266750.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001266752.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001266753.1 Involved in cell division; probably involved in intracellular septation YP_001266754.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein YP_001266755.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain YP_001266756.1 PFAM: chromosome segregation and condensation protein ScpA YP_001266757.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB YP_001266758.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001266759.1 PFAM: amino acid permease-associated region YP_001266760.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001266761.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; FAD linked oxidase domain protein YP_001266762.1 PFAM: major facilitator superfamily MFS_1 YP_001266765.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001266766.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_001266767.1 PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase YP_001266768.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001266770.2 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001266771.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein, family 3 YP_001266772.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001266773.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001266774.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001266775.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001266776.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001266777.1 PFAM: arginine N-succinyltransferase beta subunit YP_001266778.1 PFAM: arginine N-succinyltransferase beta subunit YP_001266779.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001266780.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001266782.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001266783.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001266784.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001266785.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001266786.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region YP_001266787.1 PFAM: Arc domain protein DNA binding domain protein YP_001266788.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region YP_001266789.1 PFAM: amino acid permease-associated region YP_001266791.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001266792.1 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001266793.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001266794.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001266795.1 PFAM: dehydrogenase, E1 component YP_001266796.1 PFAM: regulatory protein, AsnC/Lrp family YP_001266797.1 PFAM: glutamine synthetase, catalytic region YP_001266798.1 PFAM: major facilitator superfamily MFS_1 YP_001266799.1 PFAM: type IV pilus assembly PilZ YP_001266800.1 PFAM: FlgN family protein YP_001266801.1 PFAM: Anti-sigma-28 factor, FlgM family protein YP_001266802.1 required for the assembly of the flagellar basal body P-ring YP_001266803.1 PFAM: response regulator receiver; CheW domain protein YP_001266804.1 PFAM: MCP methyltransferase, CheR-type YP_001266805.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001266806.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001266807.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001266808.1 PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein YP_001266810.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001266811.1 makes up the distal portion of the flagellar basal body rod YP_001266812.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001266813.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001266814.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001266815.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001266816.1 With FlgK acts as a hook filament junction protein to join the flagellar filament to the hook YP_001266817.1 PFAM: glycosyl transferase, family 2 YP_001266820.1 TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase YP_001266821.1 TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain YP_001266822.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001266823.1 PFAM: glycosyl transferase, family 2 YP_001266824.1 PFAM: N-acetylneuraminic acid synthase, N-terminal domain YP_001266825.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001266826.1 TIGRFAM: methyltransferase FkbM family YP_001266827.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001266829.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YP_001266830.1 structural flagella protein YP_001266831.1 PFAM: flagellar protein FlaG protein YP_001266832.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein YP_001266833.1 flagellin specific chaperone YP_001266835.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; flagellar regulatory FleQ domain protein; SMART: AAA ATPase YP_001266836.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein YP_001266837.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001266838.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_001266839.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001266840.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001266841.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001266842.1 involved in type III protein export during flagellum assembly YP_001266843.1 rod/hook and filament chaperone YP_001266844.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001266845.1 PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001266846.1 PFAM: Hpt domain protein YP_001266847.1 PFAM: flagellar hook-length control protein YP_001266848.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001266849.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001266850.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001266851.1 PFAM: flagellar biosynthesis protein, FliO YP_001266852.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001266853.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_001266854.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001266855.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001266857.1 PFAM: protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein YP_001266858.1 PFAM: aminotransferase, class V YP_001266860.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001266862.1 TIGRFAM: D-alanine--D-alanine ligase; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein YP_001266863.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001266864.1 membrane protein involved in the flagellar export apparatus YP_001266865.1 positive regulator of class III flagellar genes YP_001266866.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001266867.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001266868.1 PFAM: response regulator receiver YP_001266869.1 PFAM: Chemotaxis phosphatase, CheZ YP_001266870.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein YP_001266871.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001266872.1 homologous to MotA; this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility; these organisms have both MotA and MotC YP_001266873.1 Homologous to MotB. These organism have both MotB and MotD. With MotC (a MotA homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. Either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility YP_001266874.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001266875.1 PFAM: CheW domain protein YP_001266876.1 PFAM: CheW domain protein YP_001266881.1 ATP-binding protein; required for proper cytochrome c maturation YP_001266882.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB YP_001266883.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein YP_001266884.1 PFAM: Heme exporter protein D (CcmD) YP_001266885.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001266886.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein YP_001266887.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001266888.1 PFAM: cytochrome C biogenesis protein YP_001266889.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001266892.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001266893.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein YP_001266894.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001266895.1 PFAM: peptidylprolyl isomerase, FKBP-type YP_001266897.1 PFAM: FAD dependent oxidoreductase YP_001266898.1 PFAM: Asp/Glu racemase YP_001266899.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001266900.1 PFAM: regulatory protein, AsnC/Lrp family YP_001266901.1 PFAM: protein of unknown function DUF6, transmembrane YP_001266903.1 PFAM: major facilitator superfamily MFS_1 YP_001266905.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001266906.1 PFAM: Ion transport protein; Ion transport 2 domain protein YP_001266907.1 PFAM: Urea transporter YP_001266908.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001266909.1 PFAM: MOFRL domain protein YP_001266910.1 TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001266911.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001266912.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001266913.1 PFAM: protein of unknown function DUF336 YP_001266914.1 PFAM: regulatory protein, TetR; Tetracycline transcriptional regulator YcdC, C-terminal domain protein YP_001266915.1 PFAM: protein of unknown function DUF808 YP_001266918.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease YP_001266919.1 PFAM: protein of unknown function DUF989 YP_001266920.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001266922.1 PFAM: polysaccharide deacetylase YP_001266923.1 TIGRFAM: Hydroxyisourate hydrolase; PFAM: Transthyretin YP_001266924.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter YP_001266925.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001266926.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001266927.1 Catalyzes the deamination of guanine YP_001266928.1 TIGRFAM: Xanthine dehydrogenase accessory protein XdhC; PFAM: protein of unknown function DUF182 YP_001266929.1 TIGRFAM: Xanthine dehydrogenase, molybdopterin binding subunit; PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001266930.1 TIGRFAM: Xanthine dehydrogenase, small subunit; PFAM: ferredoxin; molybdopterin dehydrogenase, FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein YP_001266931.1 PFAM: regulatory protein GntR, HTH YP_001266932.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain protein YP_001266933.1 interacts directly with the cell division protein ftsZ; probable receptor for the septal ring structure, may anchor it to the inner-membrane YP_001266934.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001266935.1 PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding YP_001266938.1 SMART: extracellular solute-binding protein, family 3 YP_001266939.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001266940.1 PFAM: conserved hypothetical protein 103 YP_001266941.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001266942.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001266943.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001266944.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001266946.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type YP_001266947.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001266949.1 TIGRFAM: Cytochrome c oxidase cbb3 type, accessory protein FixG; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001266950.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I YP_001266951.1 PFAM: Cbb3-type cytochrome oxidase component YP_001266952.1 CcoO; FixO YP_001266953.1 CcoN; FixN YP_001266955.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I YP_001266957.1 CcoO; FixO YP_001266958.1 CcoN; FixN YP_001266960.1 PFAM: protein of unknown function DUF1255 YP_001266961.1 PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001266962.1 SMART: extracellular solute-binding protein, family 3 YP_001266963.1 RNA polymerase sigma factor involved in the synthesis of the siderophores pyoverdine in Pseudomonas and malleobactin in Burkholderia; also involved in the synthesis of exotoxin and PrpL protease YP_001266964.1 catalyzes the specific recognition and activation of amino acids during peptide synthesis; involved in the biosynthesis of the peptide chain of pyoverdines YP_001266967.1 Involved in disulfide bond formation YP_001266968.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001266969.1 PFAM: cytochrome c biogenesis protein, transmembrane region; Thioredoxin domain YP_001266970.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001266971.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001266972.1 PFAM: cytochrome c, class I YP_001266973.1 PFAM: protein of unknown function DUF182 YP_001266975.1 PFAM: GAD-like; Domain of unknown function DUF1851 YP_001266976.1 PFAM: GAD-like; Domain of unknown function DUF1851 YP_001266978.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001266979.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001266980.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_001266981.1 PFAM: Transcription factor jumonji; SMART: transcription factor jumonji, jmjC domain protein YP_001266982.1 PFAM: aminotransferase, class V YP_001266983.1 PFAM: peptidase M19, renal dipeptidase YP_001266985.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in Pseudomonas aeruginosa this extracytoplasmic function sigma factor may be involved in the transcription of the ferric pyoverdine receptor gene, fpvA. YP_001266987.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001266989.1 SMART: helix-turn-helix domain protein YP_001266990.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase YP_001266991.1 PFAM: Electron transfer flavoprotein, alpha/beta-subunit-like YP_001266992.1 PFAM: Electron transfer flavoprotein, alpha/beta-subunit-like; Electron transfer flavoprotein, alpha subunit-like YP_001266995.1 PFAM: OmpA/MotB domain protein YP_001266996.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001266998.1 PFAM: protein of unknown function UPF0153 YP_001266999.1 PFAM: lipid-binding START domain protein YP_001267000.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001267001.1 TIGRFAM: Succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase, cytochrome b subunit YP_001267002.1 TIGRFAM: Succinate dehydrogenase, hydrophobic membrane anchor YP_001267003.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001267004.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001267005.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001267006.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001267007.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001267008.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001267009.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001267010.1 PFAM: branched-chain amino acid transport system II carrier protein YP_001267011.1 PFAM: protein of unknown function DUF599 YP_001267013.1 PFAM: Propeptide, PepSY amd peptidase M4; PepSY-associated TM helix domain protein YP_001267014.1 TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding YP_001267015.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding YP_001267016.1 TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; Taurine catabolism dioxygenase TauD/TfdA; phosphopantetheine-binding YP_001267017.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding YP_001267018.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001267019.1 PFAM: protein of unknown function DUF323 YP_001267020.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding YP_001267021.1 TIGRFAM: cyclic peptide transporter; PFAM: ABC transporter related; SMART: AAA ATPase YP_001267023.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001267024.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase YP_001267025.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001267027.1 PFAM: thioesterase superfamily protein YP_001267028.1 PFAM: thioesterase superfamily protein YP_001267029.1 molecular chaperone YP_001267030.1 PFAM: dienelactone hydrolase YP_001267031.1 PFAM: Pirin domain protein domain protein; Pirin domain protein YP_001267032.1 PFAM: amidohydrolase 2 YP_001267033.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001267034.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001267035.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001267037.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001267038.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001267040.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase YP_001267043.1 PFAM: alpha/beta hydrolase fold YP_001267045.1 PFAM: protein of unknown function UPF0118 YP_001267046.1 TIGRFAM: K+-transporting ATPase, F subunit YP_001267047.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001267048.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001267049.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_001267050.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Osmosensitive K+ channel His kinase sensor; UspA domain protein YP_001267051.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001267052.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267053.1 PFAM: aminoglycoside phosphotransferase; aminotransferase class-III YP_001267054.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001267055.1 PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; SMART: AAA ATPase YP_001267056.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267057.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267058.1 PFAM: extracellular solute-binding protein, family 5 YP_001267059.1 PFAM: extracellular solute-binding protein, family 5 YP_001267060.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein YP_001267061.1 PFAM: beta-lactamase domain protein YP_001267063.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001267064.1 3'-5' exonuclease of DNA polymerase III YP_001267065.1 PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein YP_001267067.1 PFAM: NADPH-dependent FMN reductase YP_001267068.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001267069.1 PFAM: regulatory protein, LuxR; Sigma-70, region 4 type 2 YP_001267072.1 PFAM: bacteriophage CI repressor YP_001267073.1 PFAM: phage transcriptional activator, Ogr/delta YP_001267074.1 Catalyzes the transfer of electrons from NADH to quinone YP_001267075.1 Catalyzes the transfer of electrons from NADH to quinone YP_001267076.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001267077.1 Catalyzes the transfer of electrons from NADH to quinone YP_001267078.1 Catalyzes the transfer of electrons from NADH to quinone YP_001267079.1 Catalyzes the transfer of electrons from NADH to quinone YP_001267080.1 Catalyzes the transfer of electrons from NADH to quinone YP_001267081.1 Catalyzes the transfer of electrons from NADH to quinone YP_001267082.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001267083.1 Catalyzes the transfer of electrons from NADH to quinone YP_001267084.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001267085.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001267086.1 Catalyzes the transfer of electrons from NADH to quinone YP_001267087.1 PFAM: YhhN family protein YP_001267088.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase YP_001267089.1 PFAM: NolW domain protein YP_001267091.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001267092.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter YP_001267093.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001267096.1 PFAM: aminotransferase class-III YP_001267097.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267098.1 PFAM: Spore germination protein; amino acid permease-associated region YP_001267100.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001267101.1 PFAM: phosphate transporter YP_001267102.1 PFAM: protein of unknown function DUF488 YP_001267103.1 PFAM: GCN5-related N-acetyltransferase YP_001267104.1 SMART: helix-turn-helix domain protein YP_001267105.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001267106.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001267107.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001267109.1 PFAM: Sigma-70, region 4 type 2 YP_001267111.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B YP_001267112.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B YP_001267113.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein YP_001267114.1 catalyzes the hydration of gamma-carboxygeranoyl-CoA to 3-hydroxy-gamma-carboxygeranoyl-CoA YP_001267115.1 PFAM: carboxyl transferase YP_001267116.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001267117.1 activates fatty acids by binding to coenzyme A YP_001267120.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001267121.1 TIGRFAM: trehalose synthase; trehalose synthase-fused possible maltokinase; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001267122.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001267123.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Autotransporter beta- domain protein YP_001267124.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001267125.1 TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001267127.1 TIGRFAM: malto-oligosyltrehalose synthase; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001267128.1 TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77 YP_001267129.1 TIGRFAM: malto-oligosyltrehalose trehalohydrolase; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001267130.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001267132.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_001267133.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001267134.1 PFAM: glycoside hydrolase 15-related YP_001267135.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001267136.1 PFAM: regulatory protein, TetR; Tetracycline transcriptional regulator YcdC, C-terminal domain protein YP_001267137.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001267138.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001267139.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001267140.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001267141.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001267142.1 PFAM: beta-lactamase domain protein YP_001267143.1 PFAM: Lipocalin family protein YP_001267144.1 involved in regulation of intracellular pH under alkaline conditions YP_001267145.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001267146.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001267147.1 PFAM: protein of unknown function DUF81 YP_001267149.1 PFAM: alpha/beta hydrolase fold YP_001267150.1 PFAM: FAD dependent oxidoreductase YP_001267151.1 decatenates replicating daughter chromosomes YP_001267152.1 PFAM: GCN5-related N-acetyltransferase YP_001267153.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein YP_001267154.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001267155.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001267156.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001267157.1 PFAM: NUDIX hydrolase YP_001267158.1 TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type YP_001267159.1 TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase YP_001267160.1 TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001267161.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001267162.1 TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001267163.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001267164.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001267165.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001267166.1 PFAM: cell divisionFtsK/SpoIIIE YP_001267167.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001267168.1 PFAM: AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001267169.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001267170.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001267171.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001267173.1 PFAM: glycosyl transferase, family 3 YP_001267174.1 PFAM: DsrC family protein YP_001267175.1 PFAM: DsrH family protein YP_001267176.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001267177.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001267178.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease YP_001267179.1 PFAM: protein of unknown function UPF0005 YP_001267180.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001267181.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267182.1 PFAM: ribulose bisphosphate carboxylase, large chain YP_001267183.1 PFAM: type III effector Hrp-dependent outers YP_001267184.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001267185.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001267186.1 PFAM: enolase YP_001267187.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267188.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001267189.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001267190.1 PFAM: protein of unknown function UPF0153 YP_001267191.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001267192.1 PFAM: isochorismatase hydrolase YP_001267193.1 PFAM: Endoribonuclease L-PSP YP_001267194.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267195.1 PFAM: Propeptide, PepSY amd peptidase M4 YP_001267197.1 PFAM: protein of unknown function DUF1264 YP_001267198.1 PFAM: major facilitator superfamily MFS_1 YP_001267199.1 PFAM: regulatory protein, TetR YP_001267200.1 PFAM: Chloride channel, core YP_001267201.1 PFAM: Na+/H+ antiporter NhaA YP_001267202.1 PFAM: cation transporter YP_001267203.1 TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001267204.1 TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001267205.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001267206.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein YP_001267207.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain YP_001267208.1 PFAM: Oligogalacturonate-specific porin YP_001267209.1 PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein YP_001267210.1 PFAM: extracellular solute-binding protein, family 5 YP_001267211.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267212.1 PFAM: extracellular solute-binding protein, family 5 YP_001267213.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267214.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001267215.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001267216.1 PFAM: glycoside hydrolase, family 28; Fibronectin, type III domain protein YP_001267217.1 PFAM: regulatory protein GntR, HTH; protein of unknown function UPF0074; GntR domain protein YP_001267218.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001267220.1 PFAM: regulatory protein, TetR YP_001267221.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; cytochrome c, class I; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001267222.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001267223.1 PFAM: regulatory protein, MarR YP_001267225.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase YP_001267226.1 PFAM: alpha/beta hydrolase fold YP_001267227.1 PFAM: Asp/Glu racemase YP_001267228.1 PFAM: isochorismatase hydrolase YP_001267229.1 PFAM: major facilitator superfamily MFS_1 YP_001267230.1 PFAM: outer membrane porin YP_001267232.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267233.1 PFAM: protein of unknown function DUF81 YP_001267234.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; MASE1 domain protein YP_001267235.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001267236.1 PFAM: 17 kDa surface antigen YP_001267240.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001267241.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001267242.1 PFAM: aminoglycoside phosphotransferase YP_001267243.1 PFAM: Sterol-binding domain protein YP_001267244.1 PFAM: Phosphoglycerate mutase YP_001267245.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001267246.1 PFAM: protein of unknown function DUF1003 YP_001267252.1 PFAM: ERF family protein YP_001267254.1 PFAM: isochorismatase hydrolase YP_001267256.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility C-terminal domain YP_001267257.1 PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding YP_001267259.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_001267261.1 PFAM: DoxX family protein YP_001267262.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001267263.1 PFAM: KaiA binding; SMART: AAA ATPase YP_001267264.1 PFAM: response regulator receiver YP_001267265.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001267267.1 TIGRFAM: molybdate ABC transporter, ATPase subunit; PFAM: ABC transporter related; TOBE domain protein; SMART: AAA ATPase YP_001267268.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001267269.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001267270.1 PFAM: 2-nitropropane dioxygenase, NPD YP_001267272.1 PFAM: Domain of unknown function DUF1883 YP_001267274.1 PFAM: cytochrome c, class I YP_001267275.1 PFAM: cytochrome c, class I YP_001267276.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001267277.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001267278.1 PFAM: OmpA/MotB domain protein YP_001267279.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001267280.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267281.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267282.1 PFAM: extracellular solute-binding protein, family 1 YP_001267283.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis YP_001267284.1 PFAM: protein of unknown function DUF1330 YP_001267285.1 PFAM: Alpha/beta hydrolase fold-3 domain protein YP_001267286.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267288.1 PFAM: MbtH domain protein YP_001267289.1 PFAM: Thioesterase YP_001267290.1 PFAM: isochorismatase hydrolase YP_001267291.1 PFAM: protein of unknown function DUF1615 YP_001267293.1 PFAM: ABC-3 protein YP_001267294.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001267295.1 PFAM: periplasmic solute binding protein YP_001267299.1 PFAM: Propeptide, PepSY amd peptidase M4; PepSY-associated TM helix domain protein YP_001267302.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001267303.1 PFAM: phage integrase family protein YP_001267304.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267305.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001267306.1 PFAM: luciferase family protein YP_001267308.1 PFAM: low temperature requirement A YP_001267309.1 PFAM: DSBA oxidoreductase YP_001267310.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001267311.1 PFAM: aminotransferase, class I and II YP_001267312.1 PFAM: regulatory protein, MarR YP_001267313.1 PFAM: Alginate lyase 2 YP_001267314.1 PFAM: protein of unknown function DUF1654 YP_001267315.1 PFAM: peptidase S24, S26A and S26B YP_001267319.1 catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001267321.1 TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001267323.1 PFAM: outer membrane porin YP_001267324.1 catalyzes the formation of precorrin 6x from precorrin 5 YP_001267325.1 PFAM: response regulator receiver YP_001267326.1 PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein YP_001267327.1 PFAM: MCP methyltransferase, CheR-type YP_001267328.1 PFAM: CheB methylesterase YP_001267329.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001267330.1 PFAM: response regulator receiver YP_001267331.1 PFAM: regulatory protein, TetR YP_001267332.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001267333.1 catalyzes the formation of beta-ketovaleryl-CoA from acetyl-CoA and propionyl-CoA YP_001267334.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001267335.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase YP_001267336.1 PFAM: major facilitator superfamily MFS_1 YP_001267337.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001267339.1 PFAM: protein of unknown function DUF336 YP_001267340.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein YP_001267341.1 PFAM: FAD linked oxidase domain protein YP_001267342.1 TIGRFAM: glycolate oxidase, subunit GlcD; PFAM: FAD linked oxidase domain protein YP_001267343.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001267344.1 TIGRFAM: conserverd hypothetical protein YP_001267345.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain YP_001267346.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001267347.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001267348.1 PFAM: outer membrane porin YP_001267349.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001267350.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001267351.1 PFAM: Rieske [2Fe-2S] domain protein YP_001267352.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001267353.1 PFAM: protein of unknown function DUF214 YP_001267355.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001267356.1 PFAM: regulatory protein, TetR YP_001267357.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001267358.1 SMART: extracellular solute-binding protein, family 3 YP_001267359.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein YP_001267360.1 PFAM: amino acid permease-associated region YP_001267361.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001267362.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001267363.1 PFAM: CoA-binding domain protein YP_001267364.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001267365.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001267366.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II YP_001267367.1 PFAM: aldehyde dehydrogenase YP_001267368.1 PFAM: NAD(P)H dehydrogenase (quinone) YP_001267369.1 PFAM: extracellular solute-binding protein, family 1 YP_001267370.1 PFAM: aminotransferase class-III YP_001267371.1 PFAM: regulatory protein, LuxR YP_001267372.1 PFAM: Ethanolamine utilisation protein, EutH YP_001267373.1 PFAM: regulatory protein, LuxR; Sigma-70, region 4 type 2 YP_001267374.1 TIGRFAM: FAD-linked oxidoreductase; PFAM: FAD linked oxidase domain protein YP_001267375.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001267376.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267377.1 TIGRFAM: muconate and chloromuconate cycloisomerase; PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein YP_001267378.1 PFAM: Muconolactone delta-isomerase YP_001267379.1 TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein YP_001267381.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001267382.1 PFAM: aldo/keto reductase YP_001267383.1 PFAM: protein of unknown function DUF6, transmembrane YP_001267384.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267385.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_001267386.1 PFAM: creatinase; peptidase M24 YP_001267387.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001267388.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001267389.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001267390.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001267391.1 PFAM: conserved hypothetical protein 730 YP_001267392.1 PFAM: conserved hypothetical protein 698 YP_001267393.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267394.1 PFAM: MaoC domain protein dehydratase YP_001267395.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001267396.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001267397.1 PFAM: nitroreductase YP_001267398.1 PFAM: outer membrane porin YP_001267399.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001267400.1 PFAM: regulatory protein, AsnC/Lrp family YP_001267401.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001267402.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001267403.1 PFAM: response regulator receiver; GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001267404.1 PFAM: NUDIX hydrolase YP_001267405.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001267406.1 PFAM: Carboxymuconolactone decarboxylase YP_001267407.1 PFAM: flavin reductase domain protein, FMN-binding YP_001267408.1 PFAM: aldehyde dehydrogenase YP_001267409.1 PFAM: alpha/beta hydrolase fold; Ndr family protein YP_001267410.1 PFAM: protein of unknown function DUF1185 YP_001267411.1 PFAM: luciferase family protein YP_001267412.1 PFAM: flavin reductase domain protein, FMN-binding YP_001267413.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001267414.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001267415.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001267416.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001267417.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase YP_001267419.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001267421.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267422.1 PFAM: GCN5-related N-acetyltransferase YP_001267423.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_001267424.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267425.1 PFAM: SH3, type 3 domain protein; SMART: SH3 domain protein domain protein YP_001267426.1 PFAM: outer membrane porin YP_001267427.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase YP_001267428.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter YP_001267430.1 PFAM: protein of unknown function DUF1289 YP_001267431.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001267432.1 SMART: extracellular solute-binding protein, family 3 YP_001267433.1 PFAM: cytochrome c, class I YP_001267434.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001267435.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001267436.1 PFAM: OsmC family protein; protein of unknown function DUF181 YP_001267440.1 PFAM: Rhs element Vgr protein YP_001267441.1 PFAM: protein of unknown function DUF796 YP_001267443.1 PFAM: protein of unknown function DUF876 YP_001267445.1 PFAM: Forkhead-associated protein YP_001267446.1 PFAM: protein of unknown function DUF1305 YP_001267447.1 PFAM: protein of unknown function DUF879 YP_001267448.1 PFAM: GPW/gp25 family protein YP_001267449.1 PFAM: protein of unknown function DUF877 YP_001267450.1 PFAM: uncharacterised conserved protein UCP028301 YP_001267452.1 PFAM: ImpA domain protein YP_001267453.1 PFAM: ImcF domain protein; protein of unknown function DUF1215 YP_001267454.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001267459.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_001267460.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_001267461.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_001267462.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA YP_001267463.1 TIGRFAM: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase YP_001267464.1 aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates YP_001267465.1 PFAM: ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001267467.1 PFAM: ANTAR domain protein YP_001267468.1 PFAM: AmiS/UreI transporter YP_001267469.1 PFAM: GCN5-related N-acetyltransferase YP_001267470.1 PFAM: peptidase M24; ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001267471.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001267472.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001267473.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; magnesium-translocating P-type ATPase; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001267475.1 PFAM: major facilitator superfamily MFS_1 YP_001267476.1 PFAM: GCN5-related N-acetyltransferase YP_001267477.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001267478.1 PFAM: UspA domain protein YP_001267479.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267480.1 PFAM: iron-containing alcohol dehydrogenase YP_001267481.1 PFAM: major facilitator superfamily MFS_1 YP_001267482.1 PFAM: Hydratase/decarboxylase YP_001267483.1 PFAM: helix-turn-helix domain protein YP_001267485.1 PFAM: membrane-associated protein in eicosanoid and glutathione metabolism (MAPEG) YP_001267487.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001267488.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component YP_001267489.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component YP_001267490.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001267494.1 PFAM: domain of unknown function DUF1745 YP_001267495.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein YP_001267496.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001267497.1 SMART: Rhodanese domain protein YP_001267498.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001267499.1 PFAM: FAD dependent oxidoreductase YP_001267500.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001267501.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001267502.1 PFAM: extracellular solute-binding protein, family 3 YP_001267503.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS) YP_001267504.1 PFAM: Malate/L-lactate dehydrogenase YP_001267505.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001267506.1 PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane YP_001267507.1 PFAM: major facilitator superfamily MFS_1 YP_001267508.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001267509.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001267510.1 PFAM: acriflavin resistance protein YP_001267511.1 PFAM: acriflavin resistance protein YP_001267512.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001267513.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MHYT domain protein YP_001267514.1 PFAM: protein of unknown function DUF1652 YP_001267515.1 PFAM: protein of unknown function DUF1345 YP_001267516.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001267517.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2 YP_001267518.1 PFAM: FecR protein YP_001267519.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001267520.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267521.1 PFAM: amidohydrolase 2 YP_001267522.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001267523.1 PFAM: Endoribonuclease L-PSP YP_001267525.1 PFAM: protein of unknown function DUF1028 YP_001267526.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_001267527.1 PFAM: Carbohydrate-selective porin OprB YP_001267528.1 PFAM: Pyrrolo-quinoline quinone YP_001267529.1 PFAM: Cupin 2, conserved barrel domain protein YP_001267530.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267531.1 PFAM: major facilitator superfamily MFS_1 YP_001267532.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001267533.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001267534.1 PFAM: SCP-like extracellular YP_001267535.1 PFAM: cell wall hydrolase, SleB YP_001267536.1 PFAM: Auxin Efflux Carrier YP_001267537.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267538.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267539.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001267540.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001267541.1 PFAM: Citrate transporter; Na+/H+ antiporter NhaC; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001267542.1 PFAM: FecR protein YP_001267543.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001267544.1 activates fatty acids by binding to coenzyme A YP_001267545.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001267546.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001267547.1 PFAM: regulatory protein, MarR YP_001267548.1 PFAM: secretion protein HlyD family protein YP_001267549.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001267550.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001267551.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein YP_001267552.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein YP_001267553.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001267554.1 TIGRFAM: Cytochrome c oxidase cbb3 type, accessory protein FixG; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001267556.1 PFAM: MgtC/SapB transporter YP_001267557.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_001267558.1 PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding YP_001267559.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001267560.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_001267561.1 TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001267562.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267563.1 catalyzes the formation of L-proline from L-ornithine YP_001267564.1 PFAM: regulatory protein, AsnC/Lrp family YP_001267565.1 PFAM: lipid-binding START domain protein YP_001267566.1 PFAM: protein of unknown function DUF861, cupin_3; Cupin 2, conserved barrel domain protein YP_001267568.1 TIGRFAM: aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SMART: extracellular solute-binding protein, family 3 YP_001267570.1 PFAM: regulatory protein, TetR YP_001267571.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001267575.1 PFAM: Endoribonuclease L-PSP YP_001267577.1 PFAM: protein of unknown function DUF6, transmembrane YP_001267582.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001267583.1 PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein YP_001267584.1 PFAM: Hydantoinase B/oxoprolinase YP_001267585.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267586.1 PFAM: transmembrane pair domain protein YP_001267587.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001267588.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001267591.1 TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001267592.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_001267593.1 PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001267596.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001267597.1 PFAM: peptidase U32 YP_001267598.1 PFAM: Endoribonuclease L-PSP YP_001267599.1 PFAM: protein of unknown function DUF633 YP_001267601.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267602.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001267603.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001267605.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein YP_001267606.1 PFAM: electron transport protein SCO1/SenC YP_001267607.1 PFAM: electron transport protein SCO1/SenC YP_001267609.1 PFAM: SurA N-terminal domain YP_001267610.1 PFAM: response regulator receiver YP_001267611.1 PFAM: type II secretion system protein E YP_001267616.1 PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain; Tetratricopeptide TPR_2 repeat protein YP_001267618.1 PFAM: type II secretion system protein G YP_001267620.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_001267622.1 PFAM: Curli production assembly/transport component CsgG YP_001267624.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; ATPase associated with various cellular activities, AAA_5; SMART: PAS domain containing protein; AAA ATPase YP_001267625.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001267627.1 PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001267629.1 PFAM: aldehyde dehydrogenase YP_001267630.1 PFAM: Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding; Domain of unknown function DUF1927; Domain of unknown function DUF1928 YP_001267631.1 PFAM: Radical SAM domain protein YP_001267632.1 PFAM: Quinohemoprotein amine dehydrogenase, gamma subunit YP_001267634.1 activates fatty acids by binding to coenzyme A YP_001267635.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001267636.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001267637.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001267638.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001267639.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001267640.1 PFAM: transmembrane pair domain protein YP_001267641.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001267643.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001267644.1 PFAM: aldehyde dehydrogenase YP_001267647.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001267648.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001267649.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC YP_001267650.1 TIGRFAM: RarD protein, DMT superfamily transporter YP_001267651.1 PFAM: EAL domain protein YP_001267652.1 TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001267654.1 PFAM: ThiJ/PfpI domain protein YP_001267655.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein YP_001267656.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001267657.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001267658.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001267659.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001267660.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001267661.1 PFAM: type II secretion system protein YP_001267662.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G YP_001267663.1 PFAM: Lytic transglycosylase, catalytic YP_001267664.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001267665.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001267666.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001267668.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter YP_001267669.1 TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family YP_001267670.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001267671.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001267672.1 PFAM: extracellular solute-binding protein, family 3; response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein YP_001267673.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001267674.1 PFAM: protein of unknown function DUF1272 YP_001267675.1 TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001267677.1 TIGRFAM: cobalt transporter, subunit CbtA YP_001267678.1 TIGRFAM: cobalt transporter, subunit CbtB YP_001267679.1 PFAM: GCN5-related N-acetyltransferase YP_001267680.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001267681.1 PFAM: alpha/beta hydrolase fold YP_001267682.1 PFAM: Pirin domain protein domain protein; Pirin domain protein YP_001267683.1 PFAM: protein of unknown function DUF1652 YP_001267686.1 PFAM: 2OG-Fe(II) oxygenase YP_001267687.1 PFAM: Curlin associated repeat protein YP_001267688.1 PFAM: Curlin associated repeat protein YP_001267694.1 PFAM: Rhs element Vgr protein YP_001267697.1 PFAM: Phosphoglycerate mutase YP_001267699.1 PFAM: glucose-methanol-choline oxidoreductase YP_001267700.1 PFAM: cytochrome c, class I YP_001267701.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001267702.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001267703.1 PFAM: PfkB domain protein YP_001267704.1 PFAM: major facilitator superfamily MFS_1 YP_001267705.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001267706.1 PFAM: Endonuclease I YP_001267708.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein YP_001267709.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001267710.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001267711.1 PFAM: aldo/keto reductase YP_001267712.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267713.1 PFAM: major facilitator superfamily MFS_1 YP_001267715.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267716.1 catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis YP_001267717.1 PFAM: response regulator receiver; GAF domain protein; HWE histidine kinase; Phytochrome, central region domain protein; PAS fold-2 domain protein YP_001267719.1 PFAM: regulatory protein, AsnC/Lrp family YP_001267720.1 PFAM: aminoglycoside phosphotransferase; peptidase M23B; aminotransferase class-III YP_001267721.1 PFAM: MscS Mechanosensitive ion channel YP_001267722.1 PFAM: regulatory protein, MarR YP_001267723.1 catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA YP_001267724.1 PFAM: aldehyde dehydrogenase YP_001267725.1 catalyzes the conversion of ferulic acid to feruloyl-CoA YP_001267726.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001267727.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001267728.1 PFAM: protein of unknown function DUF323 YP_001267729.1 PFAM: sulfatase YP_001267731.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001267732.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001267733.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001267735.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001267737.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267738.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001267739.1 PFAM: sodium:dicarboxylate symporter YP_001267741.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001267742.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_001267743.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001267744.1 FabF, beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. YP_001267745.1 PFAM: acriflavin resistance protein YP_001267746.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001267747.1 PFAM: regulatory protein, TetR YP_001267748.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001267749.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001267751.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001267753.1 PFAM: CinA domain protein YP_001267755.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001267756.1 PFAM: molybdopterin dehydrogenase, FAD-binding; CO dehydrogenase flavoprotein domain protein YP_001267757.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein YP_001267758.1 catalyzes the formation of acetate from pyruvate YP_001267762.1 PFAM: Integral membrane protein TerC YP_001267763.1 PFAM: Class I peptide chain release factor YP_001267765.1 PFAM: extracellular solute-binding protein, family 3 YP_001267766.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001267767.1 PFAM: protein of unknown function DUF395, YeeE/YedE YP_001267768.1 PFAM: protein of unknown function DUF395, YeeE/YedE YP_001267769.1 PFAM: sodium/hydrogen exchanger YP_001267770.1 PFAM: phosphoribosyltransferase YP_001267771.1 PFAM: UspA domain protein YP_001267772.1 PFAM: UspA domain protein YP_001267773.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; Hemerythrin HHE cation binding domain protein YP_001267775.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria YP_001267776.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; SMART: AAA ATPase YP_001267777.1 PFAM: Ion transport 2 domain protein YP_001267778.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase YP_001267779.1 PFAM: heat shock protein Hsp20 YP_001267781.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001267782.1 PFAM: GCN5-related N-acetyltransferase YP_001267783.1 PFAM: Erythromycin esterase YP_001267784.1 PFAM: phosphoribosyltransferase YP_001267786.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase YP_001267787.1 PFAM: UspA domain protein YP_001267788.1 PFAM: GCN5-related N-acetyltransferase YP_001267789.1 PFAM: UspA domain protein YP_001267790.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp YP_001267792.1 TIGRFAM: phenylacetic acid degradation operon negative regulatory protein PaaX; PFAM: PaaX domain protein; PaaX domain protein, C-terminal domain YP_001267793.1 TIGRFAM: phenylacetic acid degradation protein PaaY; PFAM: transferase hexapeptide repeat containing protein YP_001267794.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001267795.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001267796.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation YP_001267797.1 TIGRFAM: phenylacetic acid degradation protein PaaD; PFAM: thioesterase superfamily protein YP_001267798.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_001267799.1 TIGRFAM: phenylacetate-CoA ligase YP_001267800.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001267801.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001267802.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit; PFAM: phenylacetic acid catabolic family protein YP_001267803.1 TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59 YP_001267804.1 TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit; PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001267805.1 PFAM: protein of unknown function DUF485 YP_001267806.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_001267807.1 PFAM: outer membrane porin YP_001267808.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_001267811.1 PFAM: NUDIX hydrolase YP_001267812.1 PFAM: peptidase S14, ClpP YP_001267813.1 PFAM: protein of unknown function DUF72 YP_001267814.1 PFAM: Endonuclease/exonuclease/phosphatase YP_001267815.1 PFAM: phospholipase D/Transphosphatidylase YP_001267818.1 PFAM: metallothionein, family 14 YP_001267820.1 catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001267822.1 PFAM: LmbE family protein YP_001267823.1 PFAM: NodS family protein; Methyltransferase type 11; Methyltransferase type 12 YP_001267824.1 PFAM: glycosyl transferase, family 2 YP_001267825.1 TIGRFAM: Ku family containing protein; PFAM: Ku domain protein YP_001267827.1 ATP-dependent carboxylate-amine ligase YP_001267828.1 PFAM: methyltransferase small YP_001267831.1 PFAM: major facilitator superfamily MFS_1 YP_001267832.1 PFAM: aldo/keto reductase YP_001267833.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase YP_001267834.1 PFAM: Bile acid:sodium symporter YP_001267835.1 PFAM: Carotene hydroxylase YP_001267836.1 PFAM: MgtC/SapB transporter YP_001267837.1 PFAM: GCN5-related N-acetyltransferase YP_001267838.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001267843.1 PFAM: YheO domain protein YP_001267844.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001267845.1 catalyzes the formation of L-proline from L-ornithine YP_001267846.1 PFAM: amidohydrolase; Amidohydrolase 3 YP_001267847.1 PFAM: purine catabolism PurC domain protein YP_001267848.1 PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001267849.1 PFAM: TENA/THI-4 domain protein YP_001267850.1 PFAM: TENA/THI-4 domain protein YP_001267851.1 PFAM: multicopper oxidase, type 2 YP_001267852.1 PFAM: electron transport protein SCO1/SenC YP_001267853.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001267854.1 PFAM: phage integrase family protein YP_001267855.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein YP_001267856.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267857.1 PFAM: glycerate kinase YP_001267858.1 PFAM: sugar diacid recognition domain protein YP_001267859.1 PFAM: major facilitator superfamily MFS_1 YP_001267860.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rieske [2Fe-2S] domain protein YP_001267861.1 PFAM: aldo/keto reductase YP_001267862.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_001267863.1 PFAM: luciferase family protein YP_001267864.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267865.1 PFAM: membrane-bound metal-dependent hydrolase YP_001267866.1 PFAM: outer membrane porin YP_001267867.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein YP_001267868.1 TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein YP_001267869.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001267870.1 catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol YP_001267871.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001267872.1 PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit YP_001267873.1 PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein YP_001267874.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001267876.1 TIGRFAM: histidinol-phosphate phosphatase, putative; PFAM: inositol monophosphatase YP_001267877.1 PFAM: UspA domain protein YP_001267878.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001267881.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267882.1 PFAM: aldehyde dehydrogenase YP_001267884.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001267885.1 PFAM: glutamine synthetase, catalytic region YP_001267886.1 PFAM: extracellular solute-binding protein, family 1 YP_001267887.1 PFAM: FAD dependent oxidoreductase YP_001267889.1 TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001267890.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267891.1 PFAM: sugar transferase YP_001267892.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF YP_001267893.1 PFAM: glycosyl transferase, family 2 YP_001267894.1 PFAM: glycosyl transferase, group 1 YP_001267895.1 PFAM: protein of unknown function DUF535 YP_001267896.1 PFAM: glycosyl transferase, family 2 YP_001267898.1 PFAM: glycosyl transferase, family 2 YP_001267899.1 PFAM: transferase hexapeptide repeat containing protein YP_001267900.1 PFAM: GMC oxidoreductase YP_001267902.1 PFAM: polysaccharide biosynthesis protein YP_001267905.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001267907.1 PFAM: lipopolysaccharide biosynthesis protein YP_001267909.1 PFAM: polysaccharide export protein YP_001267910.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001267911.1 PFAM: short chain fatty acid transporter YP_001267912.1 TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001267913.1 TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001267914.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001267915.1 PFAM: aldo/keto reductase YP_001267916.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001267917.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase. YP_001267920.1 Represses a number of genes involved in the response to DNA damage YP_001267921.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001267922.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001267923.1 PFAM: NIPSNAP family containing protein YP_001267924.1 proposed role in polysaccahride synthesis YP_001267925.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001267926.1 PFAM: helix-turn-helix- domain containing protein, AraC type; Cupin 2, conserved barrel domain protein YP_001267927.1 PFAM: regulatory protein, IclR YP_001267928.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001267929.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001267930.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001267931.1 TIGRFAM: YD repeat protein YP_001267932.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein YP_001267934.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; PAAR repeat-containing protein YP_001267935.1 PFAM: Domain of unknown function DUF1795 YP_001267937.1 PFAM: Rhs element Vgr protein YP_001267940.1 PFAM: uncharacterised conserved protein UCP028301 YP_001267941.1 PFAM: protein of unknown function DUF877 YP_001267942.1 PFAM: GPW/gp25 family protein YP_001267943.1 PFAM: protein of unknown function DUF879 YP_001267944.1 PFAM: protein of unknown function DUF1305 YP_001267945.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001267947.1 PFAM: protein of unknown function DUF876 YP_001267949.1 PFAM: ImcF domain protein; protein of unknown function DUF1215 YP_001267951.1 PFAM: OmpA/MotB domain protein YP_001267952.1 PFAM: protein of unknown function DUF796 YP_001267953.1 PFAM: ImpA domain protein YP_001267954.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related YP_001267955.1 PFAM: major facilitator superfamily MFS_1 YP_001267956.1 PFAM: secretion protein HlyD family protein YP_001267958.1 PFAM: Auxin Efflux Carrier YP_001267959.1 PFAM: major facilitator superfamily MFS_1 YP_001267961.1 PFAM: PEBP family protein YP_001267962.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001267963.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001267964.1 PFAM: extracellular solute-binding protein, family 5 YP_001267965.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267966.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001267967.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001267968.1 PFAM: Citrate transporter YP_001267969.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_001267970.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001267971.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase YP_001267972.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase YP_001267973.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Pertactin; Autotransporter beta- domain protein YP_001267974.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001267975.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001267976.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001267977.1 PFAM: metallophosphoesterase YP_001267978.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001267980.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylguanine DNA methyltransferase, ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding YP_001267982.1 activates fatty acids by binding to coenzyme A YP_001267983.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001267986.1 PFAM: protein of unknown function DUF1329 YP_001267988.1 PFAM: protein of unknown function DUF1234 YP_001267989.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001267990.1 PFAM: Rieske [2Fe-2S] domain protein YP_001267991.1 PFAM: DSBA oxidoreductase YP_001267992.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001267993.1 PFAM: protein of unknown function DUF849 YP_001267994.1 PFAM: Taurine catabolism dioxygenase TauD/TfdA YP_001267995.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001268004.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001268007.1 PFAM: major facilitator superfamily MFS_1 YP_001268008.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001268009.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein YP_001268010.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001268011.1 PFAM: MaoC domain protein dehydratase YP_001268013.1 TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein YP_001268014.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268016.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001268017.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001268018.1 PFAM: ThiJ/PfpI domain protein YP_001268020.1 PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding YP_001268021.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001268022.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001268023.1 PFAM: helix-turn-helix, HxlR type YP_001268024.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268025.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; Male sterility C-terminal domain; KR YP_001268026.1 PFAM: protein of unknown function UPF0157 YP_001268028.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001268029.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268030.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001268031.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; uncharacterized peroxidase-related enzyme; PFAM: Carboxymuconolactone decarboxylase YP_001268032.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin YP_001268033.1 PFAM: GCN5-related N-acetyltransferase YP_001268034.1 PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp YP_001268035.1 PFAM: Mg2+ transporter protein, CorA family protein YP_001268036.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001268037.1 TIGRFAM: Alcohol dehydrogenase. zinc-binding type 1; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001268038.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268039.1 PFAM: regulatory protein, TetR YP_001268040.1 PFAM: protein of unknown function DUF1348 YP_001268041.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001268044.1 PFAM: globin YP_001268045.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001268046.1 TIGRFAM: nitrile hydratase, alpha subunit; PFAM: Nitrile hydratase alpha chain YP_001268047.1 PFAM: nitrile hydratase, beta subunit YP_001268048.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001268049.1 PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_001268050.1 PFAM: protein of unknown function DUF6, transmembrane YP_001268051.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001268052.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001268053.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001268056.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; Oxidoreductase FAD-binding domain protein YP_001268057.1 PFAM: ApbE family lipoprotein YP_001268058.1 PFAM: protein of unknown function DUF125, transmembrane YP_001268059.1 PFAM: GCN5-related N-acetyltransferase YP_001268060.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001268061.1 PFAM: ATP-binding region, ATPase domain protein domain protein YP_001268062.1 PFAM: Di-haem cytochrome c peroxidase YP_001268063.1 PFAM: response regulator receiver YP_001268064.1 PFAM: protein of unknown function DUF159 YP_001268067.1 PFAM: Helix-turn-helix, type 11 domain protein YP_001268068.1 PFAM: protein of unknown function DUF925 YP_001268069.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001268071.1 PFAM: OsmC family protein YP_001268072.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268073.1 PFAM: major facilitator superfamily MFS_1 YP_001268075.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli YP_001268076.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001268077.1 PFAM: YheO domain protein YP_001268078.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001268079.1 TIGRFAM: carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2 YP_001268080.1 PFAM: Saccharopine dehydrogenase YP_001268081.1 PFAM: putative methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001268082.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like YP_001268083.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_001268084.1 PFAM: Radical SAM domain protein YP_001268086.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2 YP_001268087.1 PFAM: Allophanate hydrolase subunit 1 YP_001268088.1 PFAM: LamB/YcsF family protein YP_001268089.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268090.1 TIGRFAM: trehalose synthase YP_001268091.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001268092.1 PFAM: protein of unknown function DUF1275 YP_001268093.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1; Osmosensory transporter coiled coil YP_001268094.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001268095.1 PFAM: protein of unknown function RIO1 YP_001268096.1 TIGRFAM: GABA permease; PFAM: amino acid permease-associated region YP_001268097.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_001268098.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_001268099.1 regulator of gab gene expression YP_001268100.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001268101.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001268102.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001268103.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001268104.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001268105.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001268106.1 PFAM: peptidase S45, penicillin amidase YP_001268113.1 PFAM: protein of unknown function DUF490 YP_001268114.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein YP_001268115.1 PFAM: GCN5-related N-acetyltransferase YP_001268116.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001268118.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001268119.1 PFAM: Catalase domain protein YP_001268120.1 PFAM: cytochrome B561 YP_001268121.1 PFAM: major facilitator superfamily MFS_1 YP_001268122.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001268124.1 PFAM: DSBA oxidoreductase YP_001268125.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001268126.1 PFAM: regulatory protein, TetR YP_001268128.1 PFAM: Bile acid:sodium symporter YP_001268129.1 PFAM: beta-lactamase YP_001268132.1 PFAM: protein of unknown function DUF74 YP_001268133.1 PFAM: protein of unknown function DUF6, transmembrane YP_001268134.1 PFAM: class II aldolase/adducin family protein YP_001268136.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein YP_001268137.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001268138.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001268139.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001268140.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268141.1 PFAM: protein of unknown function DUF419 YP_001268142.1 PFAM: protein of unknown function DUF1294 YP_001268143.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001268144.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein YP_001268145.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC YP_001268150.1 PFAM: peptidase C39, bacteriocin processing YP_001268153.1 PFAM: sulfatase YP_001268154.1 PFAM: protein of unknown function DUF899, thioredoxin family protein YP_001268155.1 SMART: phosphatidylinositol-specific phospholipase C, X region YP_001268156.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein, P47K YP_001268157.1 PFAM: Urease accessory protein UreF YP_001268158.1 PFAM: HupE/UreJ protein YP_001268159.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_001268160.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001268161.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_001268162.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_001268163.1 PFAM: Urease accessory protein UreD YP_001268164.1 PFAM: phage integrase family protein YP_001268165.1 PFAM: NnrS family protein YP_001268166.1 PFAM: DEAD_2 domain protein; SMART: DEXDc2; helicase c2 YP_001268167.1 PFAM: VRR-NUC YP_001268168.1 PFAM: major facilitator superfamily MFS_1 YP_001268170.1 PFAM: Malate/L-lactate dehydrogenase YP_001268171.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain YP_001268172.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268173.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268174.1 PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein YP_001268175.1 PFAM: major facilitator superfamily MFS_1 YP_001268176.1 PFAM: regulatory protein GntR, HTH YP_001268178.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001268179.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268180.1 PFAM: phage integrase family protein YP_001268181.1 PFAM: regulatory protein, IclR; Transcriptional regulator IclR-like YP_001268182.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001268183.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001268184.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001268186.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001268187.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001268188.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001268189.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001268190.1 PFAM: Hydratase/decarboxylase YP_001268191.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001268192.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate YP_001268193.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001268194.1 PFAM: Rieske [2Fe-2S] domain protein YP_001268195.1 PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit YP_001268196.1 PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein YP_001268197.1 PFAM: alpha/beta hydrolase fold YP_001268198.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation YP_001268199.1 PFAM: regulatory protein, LysR YP_001268201.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001268202.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001268203.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001268204.1 PFAM: Hydratase/decarboxylase YP_001268205.1 PFAM: alpha/beta hydrolase fold YP_001268206.1 PFAM: regulatory protein, TetR YP_001268207.1 PFAM: class II aldolase/adducin family protein YP_001268208.1 PFAM: Rieske [2Fe-2S] domain protein YP_001268209.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001268210.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001268211.1 PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit YP_001268212.1 PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein YP_001268213.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001268214.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent YP_001268215.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation YP_001268216.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001268217.1 PFAM: fatty acid desaturase YP_001268218.1 PFAM: aldehyde dehydrogenase YP_001268219.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001268220.1 PFAM: dienelactone hydrolase YP_001268222.1 PFAM: regulatory protein, TetR YP_001268226.1 PFAM: Prophage CP4-57 regulatory YP_001268227.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001268231.1 PFAM: Domain of unknown function DUF1845 YP_001268233.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_001268235.1 PFAM: helix-turn-helix domain protein YP_001268236.1 TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; DNA topoisomerase, type IA, zn finger domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein YP_001268239.1 PFAM: DNA repair protein RadC YP_001268244.1 PFAM: Lytic transglycosylase, catalytic YP_001268248.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001268249.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268251.1 PFAM: NUDIX hydrolase YP_001268262.1 PFAM: UMUC domain protein DNA-repair protein YP_001268263.1 PFAM: peptidase S24, S26A and S26B YP_001268264.1 PFAM: protein of unknown function DUF159 YP_001268265.1 PFAM: protein of unknown function DUF1527 YP_001268271.1 PFAM: domain of unknown function DUF1738 YP_001268274.1 PFAM: protein of unknown function DUF1528; Relaxase YP_001268278.1 PFAM: NAD(P)H dehydrogenase (quinone) YP_001268279.1 PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding YP_001268283.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001268284.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001268285.1 PFAM: aminotransferase class-III YP_001268286.1 PFAM: Beta-ketoacyl synthase-like YP_001268287.1 PFAM: Beta-ketoacyl synthase-like YP_001268289.1 PFAM: Beta-ketoacyl synthase-like YP_001268291.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268293.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001268294.1 PFAM: sigma-54 factor, interaction domain-containing protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001268297.1 PFAM: inner-membrane translocator YP_001268298.1 PFAM: inner-membrane translocator YP_001268299.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268301.1 PFAM: luciferase family protein YP_001268302.1 PFAM: NADPH-dependent FMN reductase YP_001268303.1 PFAM: Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001268304.1 PFAM: inner-membrane translocator YP_001268305.1 PFAM: inner-membrane translocator YP_001268306.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268308.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001268310.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001268311.1 PFAM: outer membrane porin YP_001268312.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268315.1 PFAM: inner-membrane translocator YP_001268316.1 PFAM: inner-membrane translocator YP_001268317.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268320.1 PFAM: UspA domain protein YP_001268321.1 TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase YP_001268322.1 PFAM: GCN5-related N-acetyltransferase YP_001268323.1 PFAM: protein of unknown function DUF861, cupin_3 YP_001268324.1 PFAM: MscS Mechanosensitive ion channel YP_001268325.1 PFAM: regulatory protein, MerR YP_001268326.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001268327.1 PFAM: protein of unknown function DUF1486 YP_001268328.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001268329.1 PFAM: amine oxidase; FAD dependent oxidoreductase YP_001268330.1 PFAM: protein of unknown function DUF1365 YP_001268331.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001268334.1 PFAM: deoxyribodipyrimidine photolyase-related protein YP_001268338.1 PFAM: protein of unknown function DUF1543 YP_001268339.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001268341.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein YP_001268343.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001268344.1 PFAM: Hemerythrin HHE cation binding domain protein YP_001268346.1 PFAM: regulatory protein, ArsR YP_001268347.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter YP_001268348.1 PFAM: low molecular weight phosphotyrosine protein phosphatase YP_001268349.1 TIGRFAM: Arsenate resistance ArsH; PFAM: NADPH-dependent FMN reductase YP_001268350.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001268351.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001268353.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KR YP_001268355.1 PFAM: AMP-dependent synthetase and ligase YP_001268357.1 TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase YP_001268360.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001268361.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001268363.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268364.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001268365.1 PFAM: Domain of unknown function DUF1852 YP_001268366.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_001268367.1 PFAM: flavin reductase domain protein, FMN-binding YP_001268368.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268369.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268370.1 PFAM: aldehyde dehydrogenase YP_001268371.1 PFAM: peptidase M19, renal dipeptidase YP_001268372.1 PFAM: BCCT transporter YP_001268375.1 PFAM: Endoribonuclease L-PSP YP_001268377.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407 YP_001268378.1 PFAM: protein of unknown function DUF403 YP_001268379.1 PFAM: transglutaminase domain protein; transglutaminase, N-terminal domain protein YP_001268381.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter YP_001268382.1 catalyzes the formation of pyruvate from serine YP_001268383.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_001268384.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001268385.1 TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative YP_001268386.1 PFAM: pyruvate carboxyltransferase YP_001268389.1 PFAM: outer membrane porin YP_001268391.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein YP_001268392.1 PFAM: iron-containing alcohol dehydrogenase YP_001268393.1 with PqqC converts a biosynthetic intermediate to pyrroloquinoline quinone YP_001268394.1 PFAM: coenzyme PQQ biosynthesis protein A YP_001268395.1 PFAM: aldehyde dehydrogenase YP_001268396.1 PFAM: Pyrrolo-quinoline quinone YP_001268397.1 PFAM: beta-lactamase domain protein YP_001268399.1 SMART: extracellular solute-binding protein, family 3 YP_001268400.1 PFAM: cytochrome c, class I YP_001268401.1 PFAM: Pyrrolo-quinoline quinone YP_001268402.1 PFAM: pentapeptide repeat protein YP_001268403.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001268404.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001268406.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein YP_001268407.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268408.1 PFAM: ABC-2 type transporter YP_001268409.1 PFAM: peptidase C26 YP_001268410.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate YP_001268411.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1 YP_001268412.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain YP_001268413.1 PFAM: aldehyde dehydrogenase YP_001268414.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001268417.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268418.1 PFAM: protein of unknown function DUF606 YP_001268421.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001268427.1 PFAM: PAAR repeat-containing protein YP_001268428.1 TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: regulatory protein, IclR; Transcriptional regulator IclR-like YP_001268429.1 PFAM: UBA/THIF-type NAD/FAD binding protein; Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein YP_001268430.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase YP_001268431.1 PFAM: NIPSNAP family containing protein YP_001268432.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase YP_001268433.1 PFAM: major facilitator superfamily MFS_1 YP_001268434.1 PFAM: Xylose isomerase domain protein TIM barrel YP_001268435.1 PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain YP_001268436.1 PFAM: regulatory protein, IclR; Transcriptional regulator IclR-like YP_001268437.1 proposed role in polysaccahride synthesis YP_001268438.1 PFAM: GAF domain protein; histidine kinase, HAMP region domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001268439.1 PFAM: aldehyde dehydrogenase YP_001268440.1 PFAM: aminotransferase class-III YP_001268441.1 PFAM: regulatory protein, LuxR YP_001268442.1 PFAM: amino acid permease-associated region YP_001268443.1 PFAM: aldehyde dehydrogenase YP_001268444.1 catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway. YP_001268445.1 PFAM: GCN5-related N-acetyltransferase YP_001268446.1 PFAM: Haem oxygenase YP_001268449.1 PFAM: sulfatase YP_001268450.1 PFAM: protein of unknown function DUF330 YP_001268451.1 PFAM: Mammalian cell entry related domain protein YP_001268452.1 PFAM: Paraquat-inducible protein A YP_001268453.1 PFAM: Paraquat-inducible protein A YP_001268455.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268456.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001268458.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001268459.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001268460.1 PFAM: alpha/beta hydrolase fold YP_001268461.1 PFAM: leucine-rich repeat protein YP_001268462.1 PFAM: UvrD/REP helicase YP_001268463.1 PFAM: Pirin domain protein domain protein YP_001268464.1 TIGRFAM: amino acid adenylation domain; PFAM: AMP-dependent synthetase and ligase YP_001268465.1 related to nicotinamidase YP_001268466.1 PFAM: Hemolysin-type calcium-binding region; Animal haem peroxidase YP_001268467.1 TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase YP_001268468.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein YP_001268469.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein YP_001268470.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001268471.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter YP_001268472.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001268473.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; Xylose isomerase domain protein TIM barrel YP_001268474.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001268475.1 PFAM: Pyridoxal-dependent decarboxylase YP_001268476.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; Helix-turn-helix, type 11 domain protein YP_001268477.1 PFAM: protein of unknown function DUF28 YP_001268478.1 PFAM: FAD dependent oxidoreductase YP_001268479.1 PFAM: major facilitator superfamily MFS_1 YP_001268480.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268482.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001268483.1 PFAM: amino acid permease-associated region YP_001268484.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001268487.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001268488.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268491.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001268492.1 PFAM: major facilitator superfamily MFS_1 YP_001268493.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268494.1 PFAM: regulatory protein, TetR YP_001268495.1 PFAM: amidohydrolase; Amidohydrolase 3 YP_001268496.1 PFAM: major facilitator superfamily MFS_1 YP_001268497.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001268499.1 PFAM: 5-nucleotidase YP_001268501.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol YP_001268505.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001268506.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001268507.1 catalyzes the formation of glutamate from glutamine YP_001268509.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001268510.1 extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway YP_001268511.1 PFAM: outer membrane porin YP_001268512.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268513.1 PFAM: LmbE family protein YP_001268514.1 TIGRFAM: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; PFAM: Dimethylmenaquinone methyltransferase YP_001268515.1 PFAM: protein of unknown function DUF453 YP_001268517.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001268518.1 PFAM: putative thiol-disulphide oxidoreductase DCC YP_001268523.1 PFAM: GCN5-related N-acetyltransferase YP_001268524.1 PFAM: HNH endonuclease YP_001268525.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001268527.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein YP_001268528.1 PFAM: regulatory protein, MerR YP_001268529.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001268530.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001268531.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001268532.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001268533.1 PFAM: ribosomal protein L35 YP_001268534.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001268535.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001268537.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001268540.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase YP_001268541.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_001268542.1 TIGRFAM: ribokinase; PFAM: PfkB domain protein; Phosphomethylpyrimidine kinase type-1 YP_001268543.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator YP_001268544.1 PFAM: inner-membrane translocator YP_001268545.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268546.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001268547.1 TIGRFAM: L-asparaginase, type II; PFAM: Asparaginase/glutaminase YP_001268548.1 TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; ATPase associated with various cellular activities, AAA_5; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase YP_001268549.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_001268550.1 PFAM: formate/nitrite transporter YP_001268551.1 PFAM: protein of unknown function DUF1654 YP_001268552.1 PFAM: Endonuclease I YP_001268554.1 PFAM: Sporulation domain protein YP_001268555.1 PFAM: FAD dependent oxidoreductase YP_001268558.1 PFAM: Integral membrane protein TerC YP_001268560.1 PFAM: regulatory protein, LysR YP_001268561.1 involved in the import of serine and threonine coupled with the import of sodium YP_001268562.1 PFAM: protein of unknown function DUF480 YP_001268565.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001268566.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001268567.1 PFAM: Integral membrane protein TerC YP_001268568.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001268569.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268570.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001268571.1 PFAM: RES YP_001268573.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_001268574.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268575.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001268576.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001268577.1 PFAM: major facilitator superfamily MFS_1 YP_001268579.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001268580.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein YP_001268581.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase, HXTX YP_001268582.1 PFAM: Aspartyl/Asparaginyl beta-hydroxylase YP_001268583.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase YP_001268584.1 PFAM: GCN5-related N-acetyltransferase YP_001268585.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001268587.1 PFAM: periplasmic binding protein YP_001268588.1 PFAM: transport system permease protein; ABC-3 protein YP_001268589.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268590.1 PFAM: GCN5-related N-acetyltransferase YP_001268592.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; Cache domain protein YP_001268593.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001268594.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001268595.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein YP_001268596.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001268597.1 PFAM: outer membrane efflux protein YP_001268598.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001268599.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001268600.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001268602.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001268603.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001268604.1 PFAM: Ferric reductase domain protein transmembrane component, N-terminal domain YP_001268605.1 PFAM: DoxX family protein YP_001268607.1 PFAM: protein of unknown function DUF692 YP_001268610.1 PFAM: leucine-rich repeat protein; SMART: leucine-rich repeat-containing protein, typical subtype YP_001268611.1 PFAM: leucine-rich repeat protein YP_001268612.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001268613.1 PFAM: major facilitator superfamily MFS_1 YP_001268614.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268615.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268616.1 PFAM: Protein of unknown function, YqcI/YcgG YP_001268617.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001268620.1 PFAM: AzlC family protein YP_001268621.1 PFAM: branched-chain amino acid transport YP_001268622.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001268623.1 PFAM: major facilitator superfamily MFS_1 YP_001268625.1 PFAM: protein of unknown function DUF461 YP_001268626.1 PFAM: electron transport protein SCO1/SenC YP_001268627.1 PFAM: HesB/YadR/YfhF-family protein; nitrogen-fixing NifU domain protein YP_001268628.1 PFAM: acyltransferase 3 YP_001268629.1 PFAM: fatty acid cistrans isomerase YP_001268630.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001268633.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_001268634.1 PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region YP_001268635.1 PFAM: uncharacterised conserved protein UCP030820 YP_001268636.1 PFAM: leucine-rich repeat protein; SMART: leucine-rich repeat-containing protein, typical subtype YP_001268637.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_001268638.1 PFAM: major facilitator superfamily MFS_1 YP_001268639.1 PFAM: major facilitator superfamily MFS_1 YP_001268640.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001268641.1 PFAM: peptidase M14, carboxypeptidase A YP_001268642.1 PFAM: Spore coat U domain protein YP_001268643.1 PFAM: fimbrial biogenesis outer membrane usher protein YP_001268645.1 PFAM: Spore coat U domain protein YP_001268646.1 PFAM: Spore coat U domain protein YP_001268647.1 PFAM: Spore coat U domain protein YP_001268648.1 PFAM: Spore coat U domain protein YP_001268649.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Phytochrome, central region domain protein; PAS fold-2 domain protein YP_001268650.1 PFAM: response regulator receiver YP_001268651.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001268653.1 PFAM: AFG1-family ATPase YP_001268655.1 PFAM: AMP-dependent synthetase and ligase YP_001268656.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268657.1 PFAM: CBS domain containing protein; HPP family protein+B94 YP_001268658.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein YP_001268659.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001268660.1 PFAM: Propeptide, PepSY amd peptidase M4 YP_001268661.1 PFAM: Propeptide, PepSY amd peptidase M4 YP_001268663.1 PFAM: phage integrase family protein YP_001268675.1 PFAM: Domain of unknown function DUF1833 YP_001268677.1 PFAM: Prophage tail length tape measure YP_001268680.1 PFAM: Ig domain protein, group 2 domain protein YP_001268688.1 TIGRFAM: phage putative head morphogenesis protein, SPP1 gp7 family YP_001268690.1 PFAM: protein of unknown function DUF264 YP_001268699.1 PFAM: bacteriophage Lambda NinG family protein YP_001268700.1 PFAM: NinB family protein YP_001268708.1 PFAM: peptidase S24, S26A and S26B YP_001268711.1 PFAM: protein of unknown function DUF1654 YP_001268715.1 PFAM: protein of unknown function DUF551 YP_001268721.1 PFAM: siphovirus Gp157 family protein YP_001268737.1 PFAM: Prophage CP4-57 regulatory YP_001268738.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001268740.1 PFAM: protein of unknown function DUF1289 YP_001268741.2 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001268742.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_001268743.1 TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453 YP_001268744.1 Catalyzes the conversion of citrate to isocitrate YP_001268745.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001268746.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001268747.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001268748.1 PFAM: protein of unknown function DUF785 YP_001268750.1 TIGRFAM: alpha-L-glutamate ligase-like protein YP_001268751.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein YP_001268752.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001268753.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001268754.1 PFAM: UspA domain protein YP_001268755.1 catalyzes the formation of 2-dehydropantoate from (R)-pantoate YP_001268756.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001268759.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein YP_001268761.1 PFAM: lipolytic enzyme, G-D-S-L family YP_001268762.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268763.1 PFAM: protein of unknown function DUF214 YP_001268764.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001268766.1 PFAM: DoxX family protein YP_001268767.1 PFAM: Lytic transglycosylase, catalytic YP_001268768.1 PFAM: TatD-related deoxyribonuclease YP_001268769.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001268772.1 PFAM: CHAD domain containing protein YP_001268774.1 PFAM: Patatin YP_001268775.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA N-terminal domain YP_001268776.1 PFAM: histone family protein DNA-binding protein YP_001268777.1 TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001268778.1 binds and unfolds substrates as part of the ClpXP protease YP_001268779.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001268780.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001268782.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001268783.1 PFAM: extracellular solute-binding protein, family 1 YP_001268785.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001268786.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001268787.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001268788.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268789.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase YP_001268790.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein YP_001268791.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein YP_001268792.1 PFAM: helix-turn-helix domain protein YP_001268793.1 involved in the transport of C4-dicarboxylates across the membrane YP_001268794.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001268795.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001268797.1 PFAM: transmembrane pair domain protein YP_001268798.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268799.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer YP_001268801.1 PFAM: Endoribonuclease L-PSP YP_001268802.1 PFAM: FAD dependent oxidoreductase YP_001268803.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001268804.1 PFAM: protein of unknown function DUF81 YP_001268805.1 PFAM: Phosphoglycerate mutase YP_001268806.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_001268807.1 PFAM: major facilitator superfamily MFS_1 YP_001268808.1 PFAM: ABC transporter related; SbmABacA family protein; ABC transporter domain protein; SMART: AAA ATPase YP_001268809.1 PFAM: protein of unknown function DUF6, transmembrane YP_001268812.1 PFAM: creatinase; peptidase M24 YP_001268816.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001268817.1 PFAM: isochorismatase hydrolase YP_001268818.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001268819.1 PFAM: protein of unknown function DUF6, transmembrane YP_001268820.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_001268821.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001268822.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001268823.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001268824.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001268825.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001268829.1 PFAM: zinc finger, DksA/TraR C4-type YP_001268830.1 PFAM: Integrase, catalytic region YP_001268831.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001268832.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001268833.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001268834.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001268835.1 PFAM: AMP-dependent synthetase and ligase YP_001268836.1 SMART: leucine-rich repeat-containing protein, typical subtype YP_001268837.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001268838.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268839.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_001268840.1 catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate YP_001268841.1 PFAM: protein of unknown function UPF0118 YP_001268842.1 PFAM: peptidase U32 YP_001268843.1 PFAM: protein of unknown function DUF411 YP_001268845.1 PFAM: alpha/beta hydrolase fold YP_001268846.1 PFAM: DinB family protein YP_001268847.1 PFAM: AFG1-family ATPase YP_001268848.1 PFAM: glucose sorbosone dehydrogenase YP_001268850.1 catalyzes the formation of putrescine from agmatine YP_001268851.1 PFAM: extracellular solute-binding protein, family 1 YP_001268852.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268853.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001268854.1 TIGRFAM: RNA polymerase sigma-70; PFAM: FecR protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001268855.1 SMART: Water Stress and Hypersensitive response YP_001268857.1 PFAM: protein of unknown function DUF883, ElaB YP_001268858.1 PFAM: tRNA--hydroxylase YP_001268859.1 PFAM: UspA domain protein YP_001268861.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region YP_001268862.1 PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit YP_001268863.1 catalyzes the oxidation of formate to carbon dioxide and hydrogen using NAD or NADP as the acceptor YP_001268864.1 PFAM: ProQ activator of osmoprotectant transporter ProP YP_001268865.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001268866.1 PFAM: aminotransferase class-III YP_001268867.1 PFAM: peptidase C26 YP_001268868.1 PFAM: glutamine synthetase, catalytic region YP_001268869.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001268870.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268871.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001268872.1 PFAM: glutathione-dependent formaldehyde-activating, GFA YP_001268873.1 PFAM: helix-turn-helix- domain containing protein, AraC type; transcription activator, effector binding YP_001268875.1 PFAM: regulatory protein, TetR YP_001268878.1 PFAM: Lysine exporter protein (LYSE/YGGA) YP_001268879.1 PFAM: Chorismate mutase YP_001268880.1 SMART: PDZ/DHR/GLGF domain protein YP_001268881.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase, DuS YP_001268882.2 TIGRFAM: transaldolase; PFAM: Transaldolase YP_001268884.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS YP_001268885.1 PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein YP_001268886.1 PFAM: type IV pilus assembly PilZ YP_001268887.1 PFAM: VacJ family lipoprotein YP_001268890.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001268892.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001268893.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001268894.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214 YP_001268895.1 TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase YP_001268896.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214 YP_001268897.1 PFAM: type IV pilus assembly PilZ YP_001268898.1 PFAM: glycerophosphoryl diester phosphodiesterase YP_001268899.1 catalyzes the conversion of NADPH to NADH YP_001268900.1 PFAM: ApbE family lipoprotein YP_001268901.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001268902.1 TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001268904.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like YP_001268905.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001268906.1 PFAM: regulatory protein, TetR YP_001268907.1 Represses a number of genes involved in the response to DNA damage YP_001268911.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001268912.1 PFAM: protein of unknown function DUF1653 YP_001268913.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001268914.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001268916.1 PFAM: UspA domain protein YP_001268917.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001268918.1 PFAM: Lytic transglycosylase, catalytic YP_001268919.1 PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein YP_001268920.1 PFAM: response regulator receiver; CheW domain protein YP_001268922.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region YP_001268923.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001268924.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001268925.1 PFAM: glycosyl transferase, group 1 YP_001268926.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV YP_001268927.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain YP_001268928.1 PFAM: protein of unknown function DUF903 YP_001268929.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001268930.1 TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001268932.1 Required for the de novo synthesis of pyroxidine via the pdxA branch; catalyzes the formation of 3-hydroxy-4-phospho-hydroxy-alpha-ketobutyrate from erythronate-4-phosphate YP_001268933.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001268935.1 catalyzes the conversion of citrate to isocitrate YP_001268936.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein YP_001268937.1 PFAM: pseudouridine synthase YP_001268939.1 PFAM: Peptidase M15A YP_001268940.1 PFAM: glutaredoxin 2 YP_001268941.1 PFAM: Rh family protein/ammonium transporter YP_001268942.1 PFAM: protein of unknown function DUF883, ElaB YP_001268945.1 dGTPase family type 3 subfamily, presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001268946.1 PFAM: regulatory protein, LuxR; response regulator receiver YP_001268947.1 TIGRFAM: PAS sensor protein; PFAM: extracellular solute-binding protein, family 3; response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001268948.1 PFAM: protein of unknown function DUF469 YP_001268949.1 TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C YP_001268950.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; CHASE domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001268951.2 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001268952.1 PFAM: ribosome modulation factor YP_001268953.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001268955.1 PFAM: response regulator receiver; ANTAR domain protein YP_001268956.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1 YP_001268957.1 PFAM: protein kinase; SMART: protein phosphatase 2C domain protein; serine/threonine protein kinase YP_001268958.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_001268959.1 PFAM: OmpA/MotB domain protein; OmpF family protein YP_001268960.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in Pseudomonas fluorescens and P. aeruginosa regulates outer membrane protein OprF expression YP_001268961.1 PFAM: Conserved TM helix repeat-containing protein YP_001268963.1 PFAM: Mg2+ transporter protein, CorA family protein YP_001268964.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001268966.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001268967.1 PFAM: protein of unknown function DUF299 YP_001268968.1 PFAM: NAD-glutamate dehydrogenase YP_001268970.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_001268971.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_001268972.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001268973.1 PFAM: FecR protein YP_001268974.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001268977.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268978.1 PFAM: GCN5-related N-acetyltransferase YP_001268979.1 PFAM: AraC protein, arabinose-binding/dimerisation; SMART: helix-turn-helix- domain containing protein, AraC type YP_001268980.1 PFAM: Cupin 2, conserved barrel domain protein YP_001268981.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001268982.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001268983.1 PFAM: secretion protein HlyD family protein YP_001268984.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001268985.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001268986.1 PFAM: acriflavin resistance protein YP_001268987.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001268988.1 TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding YP_001268989.1 PFAM: CsbD family protein YP_001268990.1 PFAM: outer membrane porin YP_001268991.1 TIGRFAM: citrate/H+ symporter, CitMHS family; PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit YP_001268992.1 PFAM: sodium:dicarboxylate symporter YP_001268993.1 PFAM: protein of unknown function DUF453 YP_001268994.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001268997.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; Mannitol dehydrogenase, C-terminal domain YP_001268998.1 TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001268999.1 PFAM: thioesterase superfamily protein YP_001269000.1 PFAM: iron-containing alcohol dehydrogenase YP_001269001.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001269002.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001269003.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269004.1 PFAM: beta-lactamase domain protein YP_001269006.1 PFAM: protein of unknown function DUF202 YP_001269007.1 PFAM: protein of unknown function DUF1329 YP_001269008.1 PFAM: protein of unknown function DUF1302 YP_001269009.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269010.1 PFAM: major facilitator superfamily MFS_1 YP_001269011.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001269012.1 PFAM: AMP-dependent synthetase and ligase YP_001269013.1 PFAM: class II aldolase/adducin family protein YP_001269014.1 PFAM: dihydrodipicolinate synthetase YP_001269015.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease YP_001269016.1 PFAM: major facilitator superfamily MFS_1 YP_001269018.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5 YP_001269019.1 PFAM: protein of unknown function DUF58 YP_001269021.1 PFAM: von Willebrand factor, type A YP_001269022.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001269025.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase YP_001269026.1 PFAM: SMC domain protein YP_001269027.1 PFAM: glutaredoxin; Glutathione S-transferase, N-terminal domain YP_001269033.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1, membrane alanine aminopeptidase-like YP_001269035.1 PFAM: protein of unknown function DUF1315 YP_001269036.1 PFAM: Rhomboid family protein YP_001269037.1 PFAM: metallophosphoesterase YP_001269038.1 catalyzes the phosphorylation of NAD to NADP YP_001269039.1 PFAM: Domain of unknown function DUF1853 YP_001269040.1 PFAM: cytochrome B561 YP_001269042.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein YP_001269043.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein YP_001269045.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001269046.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001269048.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001269050.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269051.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001269052.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001269053.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001269055.1 PFAM: pili assembly chaperone YP_001269057.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001269058.1 PFAM: EAL domain protein; response regulator receiver YP_001269059.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein YP_001269060.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001269061.1 PFAM: Fimbrial protein-like YP_001269062.1 PFAM: pili assembly chaperone YP_001269063.1 PFAM: fimbrial biogenesis outer membrane usher protein YP_001269064.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001269065.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001269067.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001269068.1 catalyzes the conversion of O-succinylhomoserine into homocysteine YP_001269069.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001269070.1 PFAM: Colicin V production protein YP_001269071.1 PFAM: Sporulation domain protein YP_001269072.1 TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle domain protein YP_001269073.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001269074.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_001269075.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001269076.1 PFAM: Peptidoglycan-binding LysM YP_001269077.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001269078.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001269079.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001269080.1 PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12 YP_001269081.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001269082.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001269083.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269084.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001269085.1 PFAM: heat shock protein Hsp20 YP_001269087.1 PFAM: dihydrouridine synthase, DuS YP_001269088.1 PFAM: thioesterase superfamily protein YP_001269090.1 PFAM: regulatory protein, TetR YP_001269091.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001269092.1 PFAM: secretion protein HlyD family protein YP_001269093.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001269094.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001269095.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001269096.1 PFAM: Cupin 2, conserved barrel domain protein YP_001269097.1 PFAM: protein of unknown function DUF1285 YP_001269099.1 PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001269100.1 PFAM: regulatory protein, TetR YP_001269101.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease YP_001269102.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001269103.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001269104.1 PFAM: aminodeoxychorismate lyase YP_001269105.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_001269106.2 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001269107.1 carries the fatty acid chain in fatty acid biosynthesis YP_001269108.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001269109.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase YP_001269110.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001269111.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001269112.1 PFAM: protein of unknown function DUF177 YP_001269113.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001269114.1 TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49 YP_001269115.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001269116.1 TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001269117.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein YP_001269118.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001269119.1 PFAM: low molecular weight phosphotyrosine protein phosphatase YP_001269120.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001269121.1 PFAM: protein of unknown function DUF343 YP_001269122.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001269123.1 PFAM: Biopolymer transport protein ExbD/TolR YP_001269124.1 PFAM: MotA/TolQ/ExbB proton channel YP_001269125.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein YP_001269127.1 PFAM: ABC-2 type transporter YP_001269128.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001269129.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001269130.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001269132.1 PFAM: Fimbrial protein-like YP_001269133.1 PFAM: pili assembly chaperone YP_001269135.1 TIGRFAM: outer membrane autotransporter barrel domain; PFAM: Pertactin; Autotransporter beta- domain protein YP_001269137.1 PFAM: YD repeat-containing protein YP_001269142.1 TIGRFAM: YD repeat protein; PFAM: YD repeat-containing protein YP_001269143.1 PFAM: fimbrial biogenesis outer membrane usher protein YP_001269144.1 PFAM: Fimbrial protein-like YP_001269147.1 PFAM: protein of unknown function DUF815 YP_001269148.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001269149.1 PFAM: glutathione peroxidase YP_001269150.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001269151.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001269152.1 putative metalloprotease YP_001269153.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_001269154.1 PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B YP_001269155.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001269157.1 TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II YP_001269158.1 PFAM: protein of unknown function DUF1127 YP_001269159.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269160.1 PFAM: protein of unknown function DUF81 YP_001269161.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269162.1 PFAM: regulatory protein, MarR YP_001269163.1 PFAM: OsmC family protein YP_001269164.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001269167.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269168.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001269169.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269170.1 PFAM: major facilitator superfamily MFS_1 YP_001269172.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001269173.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001269174.1 TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase YP_001269175.1 PFAM: Mg2+ transporter protein, CorA family protein YP_001269176.1 PFAM: glutamine amidotransferase class-I YP_001269178.1 PFAM: protein of unknown function DUF1260 YP_001269180.1 PFAM: sulfatase YP_001269182.1 PFAM: zinc/iron permease YP_001269184.1 PFAM: Ankyrin YP_001269187.1 PFAM: nucleoside:H+ symporter; major facilitator superfamily MFS_1 YP_001269188.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001269189.1 PFAM: alpha/beta hydrolase fold YP_001269191.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001269192.1 involved in methylation of ribosomal protein L3 YP_001269193.1 PFAM: isochorismatase hydrolase YP_001269195.1 PFAM: Smr protein/MutS2 YP_001269196.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001269197.1 PFAM: glutaredoxin; Glutathione S-transferase, N-terminal domain YP_001269198.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain YP_001269199.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease YP_001269200.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001269202.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001269203.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001269204.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001269206.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein YP_001269209.1 PFAM: transferase hexapeptide repeat containing protein YP_001269210.1 PFAM: ABC-2 type transporter YP_001269211.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001269212.1 PFAM: lipopolysaccharide biosynthesis protein YP_001269213.1 PFAM: polysaccharide export protein YP_001269214.1 PFAM: glycosyl transferase, family 2; TPR repeat-containing protein; Capsule polysaccharide biosynthesis protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001269215.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001269216.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001269217.1 TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; hydrolase, HAD-superfamily, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; PFAM: acylneuraminate cytidylyltransferase YP_001269218.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001269220.1 PFAM: Capsule polysaccharide biosynthesis protein YP_001269221.1 PFAM: Capsule polysaccharide biosynthesis protein YP_001269222.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001269223.1 PFAM: sulfatase YP_001269224.1 PFAM: GCN5-related N-acetyltransferase YP_001269225.1 PFAM: Capsule polysaccharide biosynthesis protein YP_001269226.1 PFAM: Phytanoyl-CoA dioxygenase YP_001269228.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aminotransferase, class I and II; aminotransferase class-III YP_001269229.1 PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR; Beta-ketoacyl synthase-like; Acyl transferase YP_001269230.1 PFAM: glycosyl transferase, family 2 YP_001269231.1 TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001269232.1 PFAM: ABC-2 type transporter YP_001269233.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001269234.1 PFAM: glycosyl transferase, family 2; Methyltransferase type 11; Methyltransferase type 12 YP_001269236.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001269237.1 PFAM: glycosyl transferase, family 2 YP_001269238.1 PFAM: transferase hexapeptide repeat containing protein; WxcM domain protein, C-terminal domain protein YP_001269239.1 PFAM: GtrA family protein YP_001269240.1 PFAM: glycosyl transferase, family 2 YP_001269241.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase YP_001269242.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001269243.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001269244.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001269245.1 PFAM: glycosyl transferase, family 4 YP_001269246.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain YP_001269247.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase YP_001269249.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001269250.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001269251.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001269252.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate and catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001269253.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein YP_001269254.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001269255.1 negatively supercoils closed circular double-stranded DNA YP_001269256.1 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway YP_001269257.1 Involved in ubiquinone biosynthesis YP_001269258.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001269259.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001269261.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001269262.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001269263.1 PFAM: DSBA oxidoreductase YP_001269264.1 PFAM: Rhodanese domain protein YP_001269265.1 PFAM: BolA family protein YP_001269267.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001269269.1 PFAM: protein of unknown function DUF6, transmembrane YP_001269270.1 PFAM: protein of unknown function DUF344 YP_001269271.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001269272.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase YP_001269273.1 PFAM: GCN5-related N-acetyltransferase YP_001269274.1 PFAM: peptidase M20; peptidase M42 family protein YP_001269275.1 PFAM: protein of unknown function UPF0270 YP_001269276.1 PFAM: carbon storage regulator YP_001269277.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001269284.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_001269285.1 PFAM: protein of unknown function DUF485 YP_001269286.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system YP_001269290.1 PFAM: VacJ family lipoprotein YP_001269291.1 PFAM: Patatin YP_001269292.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001269293.1 blocks the formation of polar Z-ring septums YP_001269294.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase YP_001269295.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001269296.1 PFAM: pseudouridine synthase YP_001269297.1 catalyzes the removal of amino acids from the N termini of peptides YP_001269299.1 PFAM: MscS Mechanosensitive ion channel YP_001269300.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001269302.1 PFAM: type I phosphodiesterase/nucleotide pyrophosphatase YP_001269303.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001269304.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001269305.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001269306.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001269307.1 TIGRFAM: Quinone oxidoreductase putative, PIG3; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001269308.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001269309.1 PFAM: EAL domain protein YP_001269311.1 PFAM: helix-turn-helix domain protein YP_001269312.1 PFAM: protein of unknown function DUF1232 YP_001269313.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type YP_001269314.1 TIGRFAM: pca operon transcription factor PcaQ; PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269317.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001269318.1 PFAM: major facilitator superfamily MFS_1 YP_001269319.1 PFAM: fumarylacetoacetate (FAA) hydrolase YP_001269320.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001269321.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001269322.1 TIGRFAM: nitrite reductase [NAD(P)H], small subunit YP_001269323.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein YP_001269324.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; flavodoxin/nitric oxide synthase YP_001269325.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24 YP_001269326.1 Required for efficient pilin antigenic variation YP_001269327.1 PFAM: small multidrug resistance protein YP_001269328.1 PFAM: phospholipid/glycerol acyltransferase; major facilitator superfamily MFS_1 YP_001269329.1 PFAM: amidohydrolase 2 YP_001269330.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001269331.1 PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001269332.1 PFAM: major facilitator superfamily MFS_1 YP_001269333.1 PFAM: Na+/solute symporter; response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001269334.1 PFAM: protein of unknown function DUF195 YP_001269335.1 PFAM: Sel1 domain protein repeat-containing protein YP_001269338.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation YP_001269339.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269341.1 PFAM: glutathione peroxidase; Redoxin domain protein YP_001269343.1 PFAM: major facilitator superfamily MFS_1 YP_001269344.1 PFAM: regulatory protein, MarR YP_001269345.1 PFAM: glycoside hydrolase, family 5 YP_001269346.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001269347.1 PFAM: Phosphoglycerate mutase YP_001269348.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001269349.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_001269350.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001269351.1 cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase YP_001269352.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_001269353.1 TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase YP_001269354.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001269355.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001269356.1 PFAM: NLP/P60 protein YP_001269357.1 PFAM: NLP/P60 protein YP_001269358.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001269359.1 PFAM: protein of unknown function UPF0118 YP_001269361.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001269362.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001269365.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase YP_001269369.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001269370.1 TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein YP_001269371.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001269372.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001269373.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001269374.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001269375.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein YP_001269376.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001269378.1 PFAM: protein of unknown function DUF306, Meta and HslJ YP_001269379.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein YP_001269380.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related YP_001269381.1 PFAM: flavodoxin/nitric oxide synthase YP_001269384.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001269385.1 PFAM: protein of unknown function DUF1282 YP_001269386.1 PFAM: protein of unknown function DUF335, SprT; SMART: protein of unknown function SprT YP_001269387.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein YP_001269388.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269389.1 PFAM: diacylglycerol kinase YP_001269390.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2 YP_001269391.1 PFAM: DTW domain containing protein YP_001269394.1 PFAM: conserved hypothetical protein 730 YP_001269395.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001269396.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001269397.1 PFAM: CinA domain protein YP_001269399.1 PFAM: protein of unknown function DUF114 YP_001269410.1 PFAM: Domain of unknown function DUF1833 YP_001269417.1 TIGRFAM: phage protein, HK97 gp10 family; PFAM: TP901-1 ORF40 family protein YP_001269418.1 PFAM: phage head-tail adaptor, putative YP_001269421.1 TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein YP_001269423.1 PFAM: peptidase U35, phage prohead HK97 YP_001269424.1 PFAM: phage Terminase YP_001269426.1 PFAM: HNH endonuclease; SMART: HNH nuclease YP_001269429.1 PFAM: protein of unknown function DUF754 YP_001269434.1 PFAM: phage integrase family protein YP_001269435.1 PFAM: VRR-NUC YP_001269436.1 PFAM: protein of unknown function DUF1364 YP_001269437.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase YP_001269438.1 TIGRFAM: phage replication protein O; PFAM: phage replication protein O domain protein YP_001269439.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B YP_001269440.1 PFAM: protein of unknown function DUF1654 YP_001269442.1 PFAM: regulatory protein, LuxR; Sigma-70, region 4 type 2 YP_001269444.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n YP_001269458.1 PFAM: phage integrase family protein YP_001269459.1 PFAM: Zeta toxin family protein YP_001269460.1 This protein performs the mismatch recognition step during the DNA repair process YP_001269461.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001269462.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001269463.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B YP_001269464.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001269465.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001269466.1 catalyzes the modification of U13 in tRNA(Glu) YP_001269467.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001269468.1 TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase YP_001269469.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001269470.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269471.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001269472.1 PFAM: Septum formation initiator YP_001269473.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001269474.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001269475.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001269477.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; Protein of unkown function DUF1946, PP-loop ATpase YP_001269478.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001269479.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001269480.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001269481.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001269482.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001269483.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001269484.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001269485.1 PFAM: outer membrane chaperone Skp (OmpH) YP_001269486.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein YP_001269487.1 TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein YP_001269488.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001269489.1 PFAM: phosphatidate cytidylyltransferase YP_001269490.1 TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001269491.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001269492.1 Catalyzes the phosphorylation of UMP to UDP YP_001269493.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001269494.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001269495.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001269496.1 Catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001269497.1 catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate YP_001269498.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger YP_001269499.1 PFAM: plasmid maintenance system killer YP_001269500.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein YP_001269501.1 PFAM: arsenate reductase and related YP_001269503.1 PFAM: aminotransferase, class V YP_001269504.1 PFAM: Fe-S metabolism associated SufE YP_001269505.1 PFAM: UBA/THIF-type NAD/FAD binding protein YP_001269506.1 PFAM: glycoside hydrolase, family 17; glycosyl transferase, family 2 YP_001269507.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001269508.1 PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001269510.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001269511.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001269514.1 PFAM: acriflavin resistance protein YP_001269515.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001269516.1 PFAM: regulatory protein, TetR YP_001269517.1 PFAM: protein of unknown function DUF548 YP_001269519.1 PFAM: Extensin family protein YP_001269521.1 PFAM: protein of unknown function DUF72 YP_001269523.1 PFAM: peptidase M22, glycoprotease YP_001269524.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001269525.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001269528.1 PFAM: OmpA/MotB domain protein YP_001269531.1 PFAM: protein of unknown function DUF1704 YP_001269533.1 PFAM: regulatory protein, TetR YP_001269534.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001269535.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein YP_001269536.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver YP_001269537.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001269538.1 PFAM: response regulator receiver; CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Hpt domain protein YP_001269539.1 PFAM: CheW domain protein YP_001269540.1 PFAM: MCP methyltransferase, CheR-type; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein YP_001269541.1 PFAM: CheW domain protein YP_001269542.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001269543.1 PFAM: protein of unknown function DUF533 YP_001269544.1 PFAM: extracellular solute-binding protein, family 1 YP_001269545.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001269546.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001269547.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001269548.2 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001269550.1 PFAM: HicB family protein YP_001269551.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase YP_001269552.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1 YP_001269553.1 PFAM: YaeQ family protein YP_001269554.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001269558.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001269559.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001269561.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001269562.1 PFAM: sodium/hydrogen exchanger YP_001269563.1 PFAM: thioesterase superfamily protein YP_001269564.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001269565.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001269566.1 Essential for efficient processing of 16S rRNA YP_001269567.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001269568.1 TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54, G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001269569.1 PFAM: cytochrome c assembly protein YP_001269570.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region YP_001269571.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001269572.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001269574.1 PFAM: protein of unknown function DUF1289 YP_001269575.1 PFAM: transferase hexapeptide repeat containing protein YP_001269576.1 PFAM: NUDIX hydrolase YP_001269577.1 PFAM: NUDIX hydrolase YP_001269579.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein, ShlB-type YP_001269580.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein YP_001269583.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001269584.1 PFAM: Carbohydrate-selective porin OprB YP_001269585.1 PFAM: Pyrrolo-quinoline quinone YP_001269586.1 TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001269588.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001269589.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase, putative; Methyltransferase type 11; Methyltransferase type 12 YP_001269591.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001269592.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001269593.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001269594.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001269595.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001269596.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001269597.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001269598.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001269599.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001269600.1 PFAM: MucB/RseB family protein YP_001269601.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein YP_001269602.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates genes involved in alginate biosynthesis YP_001269603.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001269605.1 PFAM: protein of unknown function DUF339 YP_001269606.1 PFAM: glycine cleavage T protein (aminomethyl transferase) YP_001269607.1 PFAM: Metal-dependent hydrolase HDOD YP_001269608.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Two-component sensor kinase N-terminal domain protein YP_001269609.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001269610.1 PFAM: outer membrane porin YP_001269611.1 PFAM: Uncharacterized protein UPF0065 YP_001269613.1 PFAM: protein of unknown function DUF112, transmembrane YP_001269614.1 PFAM: putative ammonia monooxygenase YP_001269615.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein YP_001269616.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001269617.1 PFAM: Enoyl-CoA hydratase/isomerase YP_001269619.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein YP_001269621.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001269622.1 PFAM: alpha/beta hydrolase fold YP_001269623.1 TIGRFAM: sulfate transporter; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter YP_001269626.1 PFAM: protein of unknown function DUF477 YP_001269627.1 PFAM: glycoside hydrolase, family 3 domain protein YP_001269628.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein YP_001269629.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001269630.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001269634.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001269635.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein YP_001269636.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein YP_001269638.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269639.1 PFAM: NAD-dependent epimerase/dehydratase; TrkA-N domain protein; NmrA family protein YP_001269640.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269642.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001269643.1 PFAM: regulatory protein, TetR; Tetracycline transcriptional repressor MAATS-type, C-terminal domain protein YP_001269644.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001269645.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_001269646.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001269647.1 PFAM: outer membrane porin YP_001269648.1 PFAM: protein of unknown function DUF962 YP_001269649.1 TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase YP_001269650.1 TIGRFAM: 3-oxoadipate enol-lactonase; PFAM: alpha/beta hydrolase fold YP_001269651.1 Catalyzes the cycloisomerization of cis,cis-muconate YP_001269652.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001269653.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_001269654.1 TIGRFAM: benzoate transport; PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001269655.1 TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; PFAM: regulatory protein, IclR; Transcriptional regulator IclR-like YP_001269657.1 PFAM: phosphate transporter YP_001269658.1 PFAM: protein of unknown function DUF853, NPT hydrolase putative YP_001269659.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer YP_001269660.1 PFAM: glycosyl transferase, group 1 YP_001269662.1 PFAM: conserved hypothetical protein 374 YP_001269663.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001269666.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001269667.1 PFAM: type IV pilus assembly PilZ YP_001269669.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001269670.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001269671.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001269672.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_001269673.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001269675.1 PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding YP_001269676.1 TIGRFAM: AmpG-related permease; PFAM: major facilitator superfamily MFS_1 YP_001269677.1 PFAM: major facilitator superfamily MFS_1 YP_001269678.1 PFAM: MscS Mechanosensitive ion channel YP_001269679.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001269680.1 catalyzes the formation of 2-dehydropantoate from (R)-pantoate YP_001269681.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001269682.1 TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase YP_001269683.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; thiamine monophosphate synthase YP_001269684.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001269685.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001269686.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_001269688.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001269689.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001269690.1 PFAM: cell division protein FtsA YP_001269691.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein, FtsQ-type YP_001269692.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001269693.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001269694.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001269695.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein YP_001269696.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001269697.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001269698.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase, middle domain protein YP_001269699.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001269700.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001269701.1 PFAM: cell division protein FtsL YP_001269702.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase YP_001269703.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001269704.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001269705.1 PFAM: LppC family lipoprotein YP_001269706.1 PFAM: protein of unknown function UPF0102 YP_001269707.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001269708.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria YP_001269709.1 PFAM: Stringent starvation protein B YP_001269710.1 PFAM: Glutathione S-transferase, N-terminal domain YP_001269712.1 PFAM: Cytochrome b/b6, N-terminal domain; Cytochrome b/b6, C-terminal domain YP_001269713.1 TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein YP_001269714.1 forms a direct contact with the tRNA during translation YP_001269715.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001269716.1 PFAM: aldo/keto reductase YP_001269717.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001269718.1 PFAM: AFG1-family ATPase YP_001269719.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001269721.1 PFAM: protein of unknown function DUF1043 YP_001269722.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine YP_001269723.1 PFAM: regulatory protein, AsnC/Lrp family YP_001269724.1 PFAM: Colicin immunity protein/pyocin immunity protein YP_001269725.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis YP_001269726.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001269727.1 PFAM: protein of unknown function DUF34 YP_001269728.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001269729.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001269730.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001269731.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001269732.1 PFAM: extracellular solute-binding protein, family 3 YP_001269733.1 PFAM: phospholipase/Carboxylesterase YP_001269734.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001269735.1 PFAM: molybdopterin biosynthesis MoaE protein YP_001269736.1 TIGRFAM: molybdopterin converting factor, subunit 1; MoaD family protein; PFAM: thiamineS protein YP_001269737.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001269738.1 PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc YP_001269739.1 PFAM: polysaccharide deacetylase YP_001269740.1 PFAM: protein of unknown function DUF328 YP_001269741.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like YP_001269743.1 PFAM: type IV pilus assembly PilZ YP_001269744.1 PFAM: Sel1 domain protein repeat-containing protein YP_001269746.1 SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis YP_001269748.1 Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond: may enhance the production of alginate by controlling the length of the polymer chain during export YP_001269749.1 PFAM: membrane bound O-acyl transferase, MBOAT family protein YP_001269752.1 TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II; Nucleotidyl transferase; Cupin 2, conserved barrel domain protein YP_001269755.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001269756.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001269757.1 PFAM: secretion protein HlyD family protein YP_001269758.1 PFAM: major facilitator superfamily MFS_1 YP_001269759.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269760.1 PFAM: UspA domain protein YP_001269761.1 PFAM: secretion protein HlyD family protein YP_001269762.1 PFAM: protein of unknown function DUF1656 YP_001269763.1 PFAM: Fusaric acid resistance protein conserved region YP_001269764.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein YP_001269765.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269766.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001269767.1 PFAM: protein of unknown function DUF6, transmembrane YP_001269768.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001269769.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001269770.1 PFAM: FecR protein YP_001269771.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2 YP_001269773.1 PFAM: PepSY-associated TM helix domain protein YP_001269777.1 PFAM: phosphate-starvation-inducible E YP_001269780.1 PFAM: YebG family protein YP_001269781.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001269783.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain YP_001269784.1 TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969 YP_001269785.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine YP_001269786.1 PFAM: regulatory protein, IclR; Transcriptional regulator IclR-like YP_001269788.1 PFAM: alpha/beta hydrolase fold YP_001269789.1 PFAM: LrgB family protein YP_001269790.1 PFAM: LrgA family protein YP_001269791.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269792.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001269793.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001269795.1 PFAM: regulatory protein, MerR YP_001269797.1 PFAM: short-chain dehydrogenase/reductase SDR YP_001269798.1 PFAM: protein of unknown function DUF1244 YP_001269799.1 PFAM: HopJ type III effector protein YP_001269801.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001269802.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001269803.1 PFAM: Cobalamin-independent synthase MetE, N-terminal domain protein YP_001269804.1 PFAM: methylenetetrahydrofolate reductase YP_001269805.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001269806.1 PFAM: protein of unknown function DUF466 YP_001269807.1 PFAM: carbon starvation protein CstA YP_001269808.1 PFAM: type IV pilus assembly PilZ YP_001269809.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease YP_001269810.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001269811.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001269812.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Ferric reductase, NAD binding YP_001269813.1 PFAM: regulatory protein, LuxR; Autoinducer-binding domain protein YP_001269814.1 PFAM: methyltransferase small YP_001269816.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II YP_001269817.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I YP_001269818.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1 YP_001269819.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter YP_001269820.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001269821.1 TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit; PFAM: intradiol ring-cleavage dioxygenase YP_001269822.1 TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit; PFAM: intradiol ring-cleavage dioxygenase YP_001269823.1 PFAM: protein of unknown function, zinc metallopeptidase putative YP_001269824.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001269825.1 TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001269826.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269827.1 PFAM: NAD(P)H dehydrogenase (quinone) YP_001269828.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001269829.1 PFAM: protein of unknown function DUF81 YP_001269830.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269831.1 PFAM: protein of unknown function DUF156 YP_001269832.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001269833.1 PFAM: protein of unknown function DUF861, cupin_3 YP_001269834.1 TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001269835.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001269836.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269837.1 PFAM: OmpA/MotB domain protein YP_001269838.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein YP_001269840.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit YP_001269841.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase YP_001269842.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, RecC subunit YP_001269843.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001269844.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001269845.1 TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001269846.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001269847.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001269848.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit YP_001269849.1 PFAM: protein of unknown function DUF446 YP_001269851.1 TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001269853.1 PFAM: TfoX, C-terminal domain protein YP_001269854.1 PFAM: protein of unknown function DUF399 YP_001269855.1 with HmuTU is involved in the transport of hemin YP_001269856.1 PFAM: transport system permease protein; ABC-3 protein YP_001269857.1 PFAM: periplasmic binding protein YP_001269858.1 PFAM: Rieske [2Fe-2S] domain protein YP_001269859.1 Regulatory factor involved in maltose metabolism YP_001269860.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II YP_001269861.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type YP_001269862.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001269864.1 TIGRFAM: PAS sensor protein; PFAM: Na+/solute symporter; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein YP_001269865.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001269866.1 TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region YP_001269867.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001269868.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001269869.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001269870.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001269871.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001269873.1 PFAM: protein of unknown function DUF748 YP_001269874.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001269875.1 PFAM: Antibiotic biosynthesis monooxygenase YP_001269876.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria YP_001269877.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_001269878.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001269879.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001269880.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001269881.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001269882.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001269883.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001269884.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit YP_001269885.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001269886.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001269887.1 TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001269888.1 TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001269889.1 PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ YP_001269890.1 PFAM: protein of unknown function UPF0044 YP_001269892.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001269893.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001269894.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001269895.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001269896.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001269897.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001269898.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001269899.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein YP_001269900.1 PFAM: ferric-uptake regulator YP_001269901.1 PFAM: SmpA/OmlA domain protein YP_001269902.1 PFAM: cyclase/dehydrase YP_001269903.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001269904.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001269905.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease YP_001269906.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_001269907.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD linked oxidase domain protein YP_001269909.1 PFAM: phage integrase family protein YP_001269912.1 PFAM: phage integrase family protein YP_001269914.1 PFAM: protein of unknown function DUF262; protein of unknown function DUF1524 RloF YP_001269915.1 PFAM: restriction modification system DNA specificity domain YP_001269916.1 PFAM: N-6 DNA methylase YP_001269918.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; protein of unknown function DUF450; DEAD/DEAH box helicase domain protein; EcoEI R, C-terminal domain protein; SMART: DEAD-like helicases-like YP_001269919.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like YP_001269924.1 PFAM: ATPase associated with various cellular activities, AAA_5 YP_001269928.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug YP_001269931.1 PFAM: amino acid permease-associated region YP_001269932.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1 YP_001269933.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001269934.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001269935.1 PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein YP_001269936.1 PFAM: major facilitator superfamily MFS_1 YP_001269937.1 PFAM: regulatory protein GntR, HTH; GntR domain protein YP_001269938.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001269939.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001269940.1 TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_001269941.1 PFAM: GCN5-related N-acetyltransferase YP_001269942.1 PFAM: Phosphoglycerate mutase YP_001269943.1 PFAM: histone deacetylase superfamily YP_001269944.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001269945.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001269946.1 PFAM: protein of unknown function DUF6, transmembrane YP_001269947.1 TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001269948.1 PFAM: protein of unknown function DUF88 YP_001269950.1 PFAM: protein of unknown function UPF0259 YP_001269952.1 TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_001269954.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein YP_001269956.1 PFAM: regulatory protein, AsnC/Lrp family; regulatory protein, MarR YP_001269958.1 PFAM: pseudouridine synthase YP_001269959.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001269960.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain YP_001269961.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region YP_001269962.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001269963.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_001269964.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001269965.1 PFAM: Sel1 domain protein repeat-containing protein YP_001269966.1 PFAM: Domain of unknown function DUF1820 YP_001269967.1 PFAM: PhoH family protein YP_001269968.1 PFAM: protein of unknown function UPF0054 YP_001269969.1 PFAM: CBS domain containing protein; transporter-associated region YP_001269970.1 Transfers the fatty acyl group on membrane lipoproteins YP_001269971.1 PFAM: protein of unknown function DUF218 YP_001269973.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001269974.1 PFAM: Rare lipoprotein B YP_001269975.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001269976.1 PFAM: protein of unknown function DUF331 YP_001269977.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein YP_001269978.1 PFAM: peptidase U61, LD-carboxypeptidase A YP_001269979.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001269980.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001269981.1 PFAM: protein of unknown function DUF493 YP_001269982.1 PFAM: beta-lactamase; peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein YP_001269983.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein YP_001269984.1 TIGRFAM: lytic murein transglycosylase B YP_001269985.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein YP_001269986.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain YP_001269987.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001269988.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein YP_001269989.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001269990.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001269991.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair YP_001269992.1 PFAM: phosphoesterase, PA-phosphatase related; SNARE associated Golgi protein YP_001269993.1 PFAM: peptidase S16, lon domain protein YP_001269994.1 PFAM: LrgB family protein YP_001269995.1 PFAM: LrgA family protein YP_001269996.1 PFAM: MaoC domain protein dehydratase YP_001269997.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001269998.1 TIGRFAM: MJ0042 family finger-like protein YP_001269999.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS YP_001270000.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001270001.1 involved in de novo purine biosynthesis YP_001270002.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001270003.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region YP_001270004.1 PFAM: multiple antibiotic resistance (MarC)-related protein YP_001270008.1 TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein YP_001270009.1 catalyzes the formation of precorrin-3 from precorrin-2 YP_001270010.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_001270011.1 TIGRFAM: precorrin-3B synthase; PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region YP_001270012.1 TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001270013.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_001270014.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 YP_001270015.1 PFAM: protein of unknown function DUF107 YP_001270016.1 PFAM: band 7 protein YP_001270018.1 PFAM: protein of unknown function DUF461 YP_001270020.1 TIGRFAM: TonB-dependent copper receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug YP_001270021.1 PFAM: Propeptide, PepSY amd peptidase M4; PepSY-associated TM helix domain protein YP_001270022.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_001270024.1 PFAM: inner-membrane translocator YP_001270025.1 PFAM: inner-membrane translocator YP_001270026.1 PFAM: ABC transporter related YP_001270027.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001270028.1 PFAM: GCN5-related N-acetyltransferase YP_001270030.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein YP_001270033.1 PFAM: PsiF repeat protein YP_001270034.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation YP_001270035.1 PFAM: protein of unknown function DUF6, transmembrane YP_001270036.1 PFAM: alpha/beta hydrolase fold YP_001270037.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_001270038.1 PFAM: Rubrerythrin; Ferritin, Dps family protein YP_001270039.1 PFAM: AsmA family protein YP_001270041.1 PFAM: regulatory protein, TetR YP_001270042.1 PFAM: N-acylglucosamine 2-epimerase YP_001270044.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR YP_001270045.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001270046.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001270047.1 PFAM: inner-membrane translocator YP_001270048.1 PFAM: inner-membrane translocator YP_001270049.1 PFAM: Extracellular ligand-binding receptor YP_001270050.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001270051.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001270052.1 TIGRFAM: Azurin, proteobacteria; PFAM: blue (type 1) copper domain protein YP_001270053.1 PFAM: conserved hypothetical protein 730 YP_001270054.1 PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001270056.1 PFAM: protein of unknown function DUF181 YP_001270057.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001270058.1 unwinds double stranded DNA YP_001270059.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001270061.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001270062.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001270063.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase, substrate binding YP_001270064.1 TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain; Ribonuclease R winged-helix domain protein; SMART: Cold shock protein YP_001270065.1 PFAM: extracellular solute-binding protein, family 1 YP_001270066.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001270068.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001270069.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001270070.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001270071.1 TIGRFAM: HflC protein; PFAM: band 7 protein YP_001270072.1 TIGRFAM: HflK protein; PFAM: band 7 protein YP_001270073.1 PFAM: GTP-binding protein, HSR1-related YP_001270074.1 Stimulates the elongation of poly(A) tails YP_001270075.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001270076.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001270077.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin YP_001270078.1 PFAM: protein of unknown function UPF0079 YP_001270079.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031 YP_001270080.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730 YP_001270081.1 PFAM: protein of unknown function UPF0126 YP_001270082.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001270083.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001270084.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001270085.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001270086.1 PFAM: Metal-dependent hydrolase HDOD YP_001270087.1 PFAM: Rhodanese domain protein YP_001270088.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001270089.1 TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase, subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase, type 3 YP_001270091.1 PFAM: protein of unknown function DUF330 YP_001270092.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001270095.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001270096.1 PFAM: protein of unknown function UPF0227 YP_001270097.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase C-terminal domain protein YP_001270098.1 PFAM: protein of unknown function DUF1249 YP_001270099.1 PFAM: NUDIX hydrolase YP_001270101.1 TIGRFAM: putative hydroxymethylpyrimidine transporter CytX; PFAM: permease for cytosine/purines, uracil, thiamine, allantoin YP_001270102.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001270103.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein YP_001270104.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001270105.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270106.1 PFAM: small multidrug resistance protein YP_001270107.1 PFAM: FAD dependent oxidoreductase YP_001270108.1 PFAM: aldo/keto reductase YP_001270110.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001270111.1 TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001270112.1 PFAM: O-antigen polymerase YP_001270114.1 PFAM: glycosyl transferase, group 1 YP_001270117.1 PFAM: LmbE family protein YP_001270118.1 PFAM: Mig-14 family protein YP_001270119.1 PFAM: glycosyl transferase, group 1 YP_001270120.1 PFAM: Carbamoyltransferase YP_001270121.1 PFAM: protein of unknown function DUF519 YP_001270122.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter YP_001270123.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001270125.1 PFAM: acyl-CoA dehydrogenase domain protein YP_001270126.1 PFAM: peptidase U62, modulator of DNA gyrase YP_001270128.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_001270129.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001270130.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001270131.1 TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893, YccS/YhfK YP_001270132.1 SMART: extracellular solute-binding protein, family 3 YP_001270133.1 PFAM: GCN5-related N-acetyltransferase YP_001270135.1 PFAM: protein of unknown function DUF45 YP_001270136.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001270137.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001270140.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001270141.1 TIGRFAM: D-erythrose-4-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001270142.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001270143.1 PFAM: regulatory protein, ArsR; Methyltransferase type 11; Methyltransferase type 12 YP_001270144.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001270145.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_001270146.1 PFAM: protein of unknown function DUF1090 YP_001270147.1 PFAM: cytochrome c, class II YP_001270148.1 PFAM: MltA domain protein; 3D domain protein YP_001270150.1 PFAM: protein of unknown function DUF6, transmembrane YP_001270151.1 PFAM: sodium/hydrogen exchanger YP_001270152.1 PFAM: thioesterase superfamily protein YP_001270153.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001270154.1 TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase YP_001270156.1 SMART: extracellular solute-binding protein, family 3 YP_001270157.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001270158.1 PFAM: YceI family protein YP_001270159.1 PFAM: cytochrome B561 YP_001270160.1 PFAM: amine oxidase; FAD dependent oxidoreductase YP_001270162.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001270163.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001270164.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein YP_001270165.1 PFAM: CheW domain protein YP_001270166.1 PFAM: response regulator receiver; CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Hpt domain protein YP_001270167.1 PFAM: chemotaxis sensory transducer YP_001270168.1 PFAM: CheW domain protein YP_001270169.1 PFAM: response regulator receiver YP_001270170.1 PFAM: response regulator receiver YP_001270171.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001270172.1 TIGRFAM: TonB family protein YP_001270173.1 PFAM: protein of unknown function DUF179 YP_001270174.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001270175.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_001270176.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001270177.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001270178.2 heat shock protein involved in degradation of misfolded proteins YP_001270179.1 heat shock protein involved in degradation of misfolded proteins YP_001270180.1 PFAM: protein of unknown function DUF971 YP_001270181.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class II; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein YP_001270182.1 TIGRFAM: poly(3-hydroxyalkanoate) depolymerase; PFAM: alpha/beta hydrolase fold YP_001270183.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class II; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein YP_001270184.1 PFAM: regulatory protein, TetR YP_001270185.1 TIGRFAM: poly(hydroxyalkanoate) granule-associated protein; PFAM: poly granule associated family protein YP_001270186.1 TIGRFAM: poly(hydroxyalkanoate) granule-associated protein; PFAM: poly granule associated family protein YP_001270188.1 TIGRFAM: putative polyhydroxyalkanoic acid system protein YP_001270189.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001270190.1 PFAM: protein of unknown function DUF1243 YP_001270191.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein YP_001270192.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_001270193.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001270194.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001270195.1 Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif YP_001270196.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase YP_001270197.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001270198.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001270199.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer YP_001270200.1 PFAM: ABC transporter related; SMART: AAA ATPase YP_001270201.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component YP_001270202.1 PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor YP_001270203.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001270204.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001270205.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001270206.1 TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold YP_001270207.1 PFAM: N-formylglutamate amidohydrolase YP_001270208.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001270209.1 PFAM: amino acid permease-associated region YP_001270210.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001270211.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001270212.1 PFAM: protein of unknown function DUF886 YP_001270213.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein YP_001270214.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_001270215.1 PFAM: Lipocalin family protein YP_001270217.1 PFAM: protein of unknown function DUF924 YP_001270218.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001270219.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase, family 35 YP_001270220.1 PFAM: protein of unknown function UPF0153 YP_001270222.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001270223.1 Required for the synthesis of the thiazole moiety YP_001270224.1 TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp YP_001270225.1 TIGRFAM: chorismate mutase, putative; PFAM: Chorismate mutase YP_001270226.1 TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001270227.1 TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase YP_001270229.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU) YP_001270230.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001270231.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin YP_001270232.1 PFAM: Rhodanese domain protein YP_001270233.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001270234.1 PFAM: peptidase M23B YP_001270235.1 TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001270236.1 PFAM: protein of unknown function DUF610, YibQ YP_001270238.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter YP_001270239.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001270240.1 catalyzes the formation of betaine from betaine aldehyde YP_001270241.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001270243.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001270244.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_001270245.1 PFAM: protein of unknown function UPF0061 YP_001270246.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001270247.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001270248.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270249.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001270250.1 PFAM: conserved hypothetical protein 156 YP_001270251.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001270252.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001270253.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001270254.1 PFAM: Sporulation domain protein YP_001270255.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001270256.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001270257.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain YP_001270259.1 PFAM: Fimbrial assembly family protein YP_001270261.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001270262.1 PFAM: malic enzyme domain protein; malic enzyme, NAD-binding YP_001270263.1 PFAM: nuclease (SNase domain protein) YP_001270264.1 PFAM: ribosomal protein L31 YP_001270265.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001270266.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001270267.1 PFAM: Sporulation domain protein YP_001270268.1 PFAM: TM2 domain containing protein+B7201 YP_001270269.1 PFAM: NLP/P60 protein YP_001270270.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001270271.1 PFAM: alanine racemase domain protein YP_001270272.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001270273.1 PFAM: protein of unknown function YGGT YP_001270274.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_001270275.1 TIGRFAM: methionine biosynthesis protein MetW; PFAM: Methionine biosynthesis MetW protein; Methyltransferase type 11; Methyltransferase type 12 YP_001270277.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001270278.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001270280.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001270281.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001270282.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001270283.1 PFAM: protein of unknown function DUF423 YP_001270284.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001270285.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001270286.1 PFAM: protein of unknown function DUF214 YP_001270287.1 TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001270288.1 TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001270289.1 PFAM: peptidase M16 domain protein YP_001270290.1 PFAM: peptidase M16 domain protein YP_001270291.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95 YP_001270292.1 PFAM: peptidase M16 domain protein YP_001270293.1 PFAM: peptidase M16 domain protein YP_001270294.1 PFAM: alpha/beta hydrolase fold YP_001270295.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein YP_001270296.1 PFAM: Rhodanese domain protein YP_001270297.1 PFAM: regulatory protein, TetR YP_001270298.1 PFAM: aldehyde dehydrogenase YP_001270300.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; GMC oxidoreductase YP_001270301.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001270302.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001270303.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001270304.1 PFAM: Metal-dependent hydrolase HDOD YP_001270305.1 PFAM: conserved hypothetical protein 95 YP_001270306.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001270308.1 PFAM: sodium:dicarboxylate symporter YP_001270309.1 PFAM: dihydrofolate reductase region YP_001270311.1 PFAM: GTP-binding protein, HSR1-related YP_001270312.1 PFAM: extracellular solute-binding protein, family 1 YP_001270313.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001270314.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001270315.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270316.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein YP_001270317.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; Transcription regulator MerR, DNA binding YP_001270319.1 SMART: AAA ATPase YP_001270325.1 TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein YP_001270326.1 TIGRFAM: 3-isopropylmalate dehydratase, large subunit; PFAM: aconitate hydratase domain protein YP_001270327.1 PFAM: major facilitator superfamily MFS_1 YP_001270328.1 PFAM: pyruvate carboxyltransferase YP_001270329.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F YP_001270330.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270334.1 PFAM: UMUC domain protein DNA-repair protein YP_001270335.1 PFAM: peptidase S24, S26A and S26B YP_001270345.1 PFAM: thymidylate synthase YP_001270348.1 PFAM: phage integrase family protein YP_001270349.1 PFAM: phage integrase family protein YP_001270350.1 PFAM: thymidylate synthase YP_001270351.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001270352.1 PFAM: protein of unknown function DUF81 YP_001270353.1 PFAM: protein of unknown function DUF833 YP_001270354.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein YP_001270355.1 hydrolyzes diadenosine polyphosphate YP_001270356.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001270358.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001270359.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001270360.1 PFAM: SdiA-regulated domain protein YP_001270361.1 PFAM: SdiA-regulated domain protein YP_001270362.1 PFAM: fumarylacetoacetate (FAA) hydrolase YP_001270363.1 PFAM: FAD linked oxidase domain protein YP_001270364.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001270367.1 PFAM: protein of unknown function DUF523 YP_001270368.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit YP_001270372.1 PFAM: transferase hexapeptide repeat containing protein YP_001270373.1 PFAM: peptidase S45, penicillin amidase YP_001270374.1 PFAM: NLPA lipoprotein YP_001270375.1 PFAM: sigma-54 factor, interaction domain-containing protein; SMART: AAA ATPase YP_001270376.1 PFAM: protein of unknown function DUF1234 YP_001270377.1 TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001270378.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component YP_001270379.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component YP_001270380.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1 YP_001270382.1 PFAM: acriflavin resistance protein YP_001270383.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001270384.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein YP_001270385.1 PFAM: protein of unknown function DUF1568 YP_001270386.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001270387.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001270388.1 TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001270389.1 PFAM: extracellular solute-binding protein, family 1 YP_001270390.1 PFAM: extracellular solute-binding protein, family 1 YP_001270391.1 PFAM: aminotransferase class-III YP_001270392.1 PFAM: glutamine synthetase, catalytic region YP_001270393.1 PFAM: glutamine synthetase, catalytic region YP_001270394.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001270395.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001270396.1 PFAM: adenylate cyclase YP_001270397.1 PFAM: regulatory protein, AsnC/Lrp family YP_001270399.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein YP_001270400.1 TIGRFAM: conserverd hypothetical protein YP_001270401.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001270402.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001270403.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001270404.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001270405.1 PFAM: extracellular solute-binding protein, family 1 YP_001270406.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol YP_001270408.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_001270409.1 PFAM: peptidase M24; peptidase M24B, X-Pro dipeptidase/aminopeptidase domain protein YP_001270410.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_001270412.1 PFAM: protein of unknown function DUF710 YP_001270413.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase YP_001270415.1 PFAM: protein of unknown function DUF55 YP_001270416.1 PFAM: secretion protein HlyD family protein YP_001270417.1 PFAM: ABC transporter related; ABC-2 type transporter; SMART: AAA ATPase YP_001270418.1 PFAM: ABC-2 type transporter YP_001270420.1 PFAM: flagellar basal body-associated protein FliL YP_001270421.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein YP_001270422.1 PFAM: ChaC family protein YP_001270423.1 catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose YP_001270424.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein YP_001270425.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001270426.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain YP_001270427.1 PFAM: Ppx/GppA phosphatase YP_001270428.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001270431.1 PFAM: ThiJ/PfpI domain protein YP_001270432.1 PFAM: protein of unknown function DUF188 YP_001270433.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001270434.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001270435.1 PFAM: protein of unknown function DUF1289 YP_001270436.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_001270438.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2 YP_001270439.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001270440.1 PFAM: protein of unknown function DUF484 YP_001270441.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001270442.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001270444.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter YP_001270445.1 PFAM: nitrogen regulatory protein P-II YP_001270446.1 PFAM: protein of unknown function DUF526 YP_001270448.1 PFAM: Sel1 domain protein repeat-containing protein YP_001270451.1 TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001270452.1 PFAM: response regulator receiver YP_001270453.1 PFAM: regulatory protein, LuxR; response regulator receiver; transcriptional regulator domain protein; Sigma-70, region 4 type 2 YP_001270454.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: serine/threonine protein kinase YP_001270455.1 PFAM: isochorismatase hydrolase YP_001270456.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001270457.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein YP_001270458.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger YP_001270460.1 PFAM: isochorismatase hydrolase YP_001270461.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270462.1 PFAM: outer membrane porin YP_001270463.1 PFAM: protein of unknown function DUF894, DitE; major facilitator superfamily MFS_1 YP_001270464.1 PFAM: Amidohydrolase 3 YP_001270465.1 PFAM: alpha/beta hydrolase fold YP_001270467.1 PFAM: isochorismatase hydrolase YP_001270468.1 PFAM: cyclic nucleotide-binding; MscS Mechanosensitive ion channel YP_001270469.1 PFAM: FAD dependent oxidoreductase YP_001270470.1 PFAM: aldehyde dehydrogenase YP_001270471.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270472.1 PFAM: protein of unknown function DUF1338 YP_001270473.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270474.1 functions as a Na(+)/drug antiporter YP_001270475.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein YP_001270476.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase YP_001270477.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_001270480.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein YP_001270481.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA YP_001270482.1 catalyzes the oxidative deamination of D-amino acids YP_001270483.1 PFAM: regulatory protein, AsnC/Lrp family YP_001270484.1 PFAM: protein of unknown function UPF0153 YP_001270485.1 PFAM: FAD dependent oxidoreductase YP_001270487.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001270488.1 PFAM: phospholipase D/Transphosphatidylase YP_001270489.1 PFAM: major facilitator superfamily MFS_1 YP_001270490.1 PFAM: aldehyde dehydrogenase YP_001270491.1 PFAM: protein of unknown function DUF861, cupin_3 YP_001270493.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001270494.1 required for 70S ribosome assembly YP_001270495.1 PFAM: extracellular solute-binding protein, family 5 YP_001270496.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001270497.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001270498.1 catalyzes the formation of dUMP from dUTP YP_001270499.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III YP_001270500.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001270501.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001270502.1 TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase YP_001270504.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001270505.1 PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732 YP_001270506.1 Essential for recycling GMP and indirectly, cGMP YP_001270508.1 PFAM: amino acid permease-associated region YP_001270509.1 PFAM: peptidase C26 YP_001270510.1 PFAM: glutamine synthetase, catalytic region YP_001270511.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270512.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001270513.1 TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001270514.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP YP_001270516.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility C-terminal domain YP_001270517.1 TIGRFAM: TonB-system energizer ExbB type-1; PFAM: MotA/TolQ/ExbB proton channel YP_001270518.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001270519.1 TIGRFAM: TonB family protein YP_001270520.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270521.1 catalyzes branch migration in Holliday junction intermediates YP_001270522.1 PFAM: Metal-dependent hydrolase HDOD YP_001270524.1 PFAM: histone family protein DNA-binding protein YP_001270525.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001270526.1 PFAM: Rubredoxin-type Fe(Cys)4 protein YP_001270527.1 PFAM: Chorismate lyase YP_001270528.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001270529.1 PFAM: Secreted repeat of unknown function YP_001270530.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein YP_001270531.1 TIGRFAM: Phosphate regulon sensor kinase PhoR; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein YP_001270532.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region YP_001270533.1 PFAM: peptidase M23B YP_001270534.1 PFAM: response regulator receiver YP_001270535.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein YP_001270536.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001270537.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component YP_001270538.1 PFAM: binding-protein-dependent transport systems inner membrane component YP_001270539.1 TIGRFAM: phosphate binding protein YP_001270540.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001270541.1 PFAM: thioesterase superfamily protein YP_001270542.1 PFAM: Aldose 1-epimerase YP_001270544.1 PFAM: Transglycosylase-associated protein YP_001270545.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001270546.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001270548.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270549.1 catalyzes the formation of fumarate from aspartate YP_001270550.1 PFAM: helix-turn-helix- domain containing protein, AraC type YP_001270551.1 PFAM: histone deacetylase superfamily YP_001270552.1 PFAM: extracellular solute-binding protein, family 1 YP_001270553.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II YP_001270554.1 PFAM: Negative transcriptional regulator YP_001270555.1 PFAM: GCN5-related N-acetyltransferase YP_001270556.1 PFAM: GCN5-related N-acetyltransferase YP_001270557.1 catalyzes the formation of oxaloacetate from pyruvate YP_001270558.1 biotin carboxylase; with subunit B, the carboxyltansferase/biotincarboxyl carrier subunit catalyzes the formation of oxaloacetate from pyruvate YP_001270559.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270560.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS) YP_001270561.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001270562.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001270563.1 PFAM: import inner membrane translocase, subunit Tim44 YP_001270565.1 PFAM: sodium/hydrogen exchanger YP_001270566.1 PFAM: thioesterase superfamily protein YP_001270567.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001270569.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001270570.1 PFAM: Protein of unknown function DUF1826 YP_001270571.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein YP_001270574.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001270575.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12 YP_001270576.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001270577.1 PFAM: Transketolase, central region; Transketolase domain protein YP_001270578.1 PFAM: Transketolase domain protein YP_001270579.1 PFAM: major facilitator superfamily MFS_1 YP_001270580.1 PFAM: short-chain dehydrogenase/reductase SDR; KR YP_001270581.1 PFAM: regulatory protein, LysR; LysR, substrate-binding YP_001270582.1 PFAM: Methyltransferase type 12 YP_001270583.1 PFAM: outer membrane porin YP_001270584.1 PFAM: dihydrodipicolinate synthetase YP_001270585.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1 YP_001270588.1 PFAM: response regulator receiver; transcriptional regulator domain protein YP_001270589.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein YP_001270590.1 PFAM: regulatory protein, IclR; Transcriptional regulator IclR-like YP_001270591.1 TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001270592.1 TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001270593.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001270594.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein YP_001270595.1 TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_001270596.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001270597.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001270598.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001270599.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001270600.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001270601.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001270602.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001270603.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001270604.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_001270605.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease YP_001270606.1 PFAM: Cobyrinic acid a,c-diamide synthase YP_001270607.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001270608.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001270610.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001270611.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001270612.1 PFAM: protein of unknown function DUF37 YP_001270613.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates