-- dump date   	20140620_022807
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1151116000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1151116000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1151116000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116000004	Walker A motif; other site
1151116000005	ATP binding site [chemical binding]; other site
1151116000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1151116000007	Walker B motif; other site
1151116000008	arginine finger; other site
1151116000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1151116000010	DnaA box-binding interface [nucleotide binding]; other site
1151116000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
1151116000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1151116000013	putative DNA binding surface [nucleotide binding]; other site
1151116000014	dimer interface [polypeptide binding]; other site
1151116000015	beta-clamp/clamp loader binding surface; other site
1151116000016	beta-clamp/translesion DNA polymerase binding surface; other site
1151116000017	recombination protein F; Reviewed; Region: recF; PRK00064
1151116000018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116000019	Walker A/P-loop; other site
1151116000020	ATP binding site [chemical binding]; other site
1151116000021	Q-loop/lid; other site
1151116000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116000023	ABC transporter signature motif; other site
1151116000024	Walker B; other site
1151116000025	D-loop; other site
1151116000026	H-loop/switch region; other site
1151116000027	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1151116000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116000029	ATP binding site [chemical binding]; other site
1151116000030	Mg2+ binding site [ion binding]; other site
1151116000031	G-X-G motif; other site
1151116000032	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1151116000033	anchoring element; other site
1151116000034	dimer interface [polypeptide binding]; other site
1151116000035	ATP binding site [chemical binding]; other site
1151116000036	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1151116000037	active site
1151116000038	putative metal-binding site [ion binding]; other site
1151116000039	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1151116000040	sugar phosphate phosphatase; Provisional; Region: PRK10513
1151116000041	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116000042	active site
1151116000043	motif I; other site
1151116000044	motif II; other site
1151116000045	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116000046	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1151116000047	Protein of unknown function (DUF1375); Region: DUF1375; cl11456
1151116000048	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1151116000049	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1151116000050	putative dimer interface [polypeptide binding]; other site
1151116000051	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1151116000052	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1151116000053	putative dimer interface [polypeptide binding]; other site
1151116000054	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1151116000055	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116000056	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116000057	homodimer interface [polypeptide binding]; other site
1151116000058	catalytic residue [active]
1151116000059	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1151116000060	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1151116000061	dimerization interface [polypeptide binding]; other site
1151116000062	ligand binding site [chemical binding]; other site
1151116000063	NADP binding site [chemical binding]; other site
1151116000064	catalytic site [active]
1151116000065	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116000066	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116000067	putative substrate translocation pore; other site
1151116000068	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1151116000069	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116000070	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116000071	DNA binding site [nucleotide binding]
1151116000072	domain linker motif; other site
1151116000073	Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283
1151116000074	putative dimerization interface [polypeptide binding]; other site
1151116000075	putative ligand binding site [chemical binding]; other site
1151116000076	galactoside permease; Reviewed; Region: lacY; PRK09528
1151116000077	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116000078	putative substrate translocation pore; other site
1151116000079	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1151116000080	Melibiase; Region: Melibiase; pfam02065
1151116000081	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116000082	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116000083	DNA binding site [nucleotide binding]
1151116000084	domain linker motif; other site
1151116000085	Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271
1151116000086	ligand binding site [chemical binding]; other site
1151116000087	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1151116000088	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1151116000089	ligand binding site [chemical binding]; other site
1151116000090	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1151116000091	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1151116000092	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1151116000093	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1151116000094	Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: Triacylglycerol_lipase_like; cd01847
1151116000095	active site
1151116000096	catalytic triad [active]
1151116000097	oxyanion hole [active]
1151116000098	Autotransporter beta-domain; Region: Autotransporter; cl17461
1151116000099	primosomal protein DnaI; Provisional; Region: PRK02854
1151116000100	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1151116000101	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1151116000102	dimer interface [polypeptide binding]; other site
1151116000103	motif 1; other site
1151116000104	active site
1151116000105	motif 2; other site
1151116000106	motif 3; other site
1151116000107	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1151116000108	DALR anticodon binding domain; Region: DALR_1; pfam05746
1151116000109	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1151116000110	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1151116000111	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1151116000112	catalytic residues [active]
1151116000113	hypothetical protein; Provisional; Region: PRK01184
1151116000114	Cytidine and deoxycytidylate deaminase zinc-binding region. The family contains cytidine deaminases, nucleoside deaminases, deoxycytidylate deaminases and riboflavin deaminases. Also included are the apoBec family of mRNA editing enzymes.  All members...; Region: cytidine_deaminase-like; cl00269
1151116000115	active site
1151116000116	Zn binding site [ion binding]; other site
1151116000117	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1151116000118	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1151116000119	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1151116000120	active site
1151116000121	P-loop; other site
1151116000122	phosphorylation site [posttranslational modification]
1151116000123	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1151116000124	active site
1151116000125	phosphorylation site [posttranslational modification]
1151116000126	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1151116000127	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1151116000128	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1151116000129	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1151116000130	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1151116000131	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1151116000132	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1151116000133	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116000134	DNA-binding site [nucleotide binding]; DNA binding site
1151116000135	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116000136	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116000137	homodimer interface [polypeptide binding]; other site
1151116000138	catalytic residue [active]
1151116000139	hypothetical protein; Provisional; Region: PRK11020
1151116000140	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1151116000141	MOSC domain; Region: MOSC; pfam03473
1151116000142	3-alpha domain; Region: 3-alpha; pfam03475
1151116000143	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1151116000144	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116000145	dimerization interface [polypeptide binding]; other site
1151116000146	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116000147	dimer interface [polypeptide binding]; other site
1151116000148	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1151116000149	putative CheW interface [polypeptide binding]; other site
1151116000150	superoxide dismutase; Provisional; Region: PRK10925
1151116000151	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1151116000152	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1151116000153	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1151116000154	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
1151116000155	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1151116000156	[4Fe-4S] binding site [ion binding]; other site
1151116000157	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1151116000158	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1151116000159	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1151116000160	molybdopterin cofactor binding site; other site
1151116000161	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1151116000162	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1151116000163	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1151116000164	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1151116000165	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1151116000166	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1151116000167	putative glutathione S-transferase; Provisional; Region: PRK10357
1151116000168	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1151116000169	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1151116000170	dimer interface [polypeptide binding]; other site
1151116000171	N-terminal domain interface [polypeptide binding]; other site
1151116000172	putative substrate binding pocket (H-site) [chemical binding]; other site
1151116000173	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1151116000174	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1151116000175	NAD(P) binding site [chemical binding]; other site
1151116000176	catalytic residues [active]
1151116000177	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1151116000178	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116000179	putative substrate translocation pore; other site
1151116000180	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1151116000181	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1151116000182	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1151116000183	conserved cys residue [active]
1151116000184	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116000185	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1151116000186	catalytic triad [active]
1151116000187	conserved cis-peptide bond; other site
1151116000188	DJ-1 family protein; Region: not_thiJ; TIGR01383
1151116000189	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1151116000190	conserved cys residue [active]
1151116000191	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1151116000192	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1151116000193	putative NAD(P) binding site [chemical binding]; other site
1151116000194	catalytic Zn binding site [ion binding]; other site
1151116000195	benzoate transporter; Region: benE; TIGR00843
1151116000196	Benzoate membrane transport protein; Region: BenE; pfam03594
1151116000197	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1151116000198	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116000199	non-specific DNA binding site [nucleotide binding]; other site
1151116000200	salt bridge; other site
1151116000201	sequence-specific DNA binding site [nucleotide binding]; other site
1151116000202	Cupin domain; Region: Cupin_2; pfam07883
1151116000203	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1151116000204	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116000205	Coenzyme A binding pocket [chemical binding]; other site
1151116000206	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116000207	Coenzyme A binding pocket [chemical binding]; other site
1151116000208	glutathione S-transferase; Provisional; Region: PRK15113
1151116000209	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1151116000210	C-terminal domain interface [polypeptide binding]; other site
1151116000211	GSH binding site (G-site) [chemical binding]; other site
1151116000212	dimer interface [polypeptide binding]; other site
1151116000213	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1151116000214	N-terminal domain interface [polypeptide binding]; other site
1151116000215	putative dimer interface [polypeptide binding]; other site
1151116000216	putative substrate binding pocket (H-site) [chemical binding]; other site
1151116000217	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116000218	Coenzyme A binding pocket [chemical binding]; other site
1151116000219	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1151116000220	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
1151116000221	hypothetical protein; Provisional; Region: PRK10457
1151116000222	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1151116000223	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
1151116000224	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1151116000225	Walker A/P-loop; other site
1151116000226	ATP binding site [chemical binding]; other site
1151116000227	Q-loop/lid; other site
1151116000228	ABC transporter signature motif; other site
1151116000229	Walker B; other site
1151116000230	D-loop; other site
1151116000231	H-loop/switch region; other site
1151116000232	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
1151116000233	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1151116000234	Walker A/P-loop; other site
1151116000235	ATP binding site [chemical binding]; other site
1151116000236	Q-loop/lid; other site
1151116000237	ABC transporter signature motif; other site
1151116000238	Walker B; other site
1151116000239	D-loop; other site
1151116000240	H-loop/switch region; other site
1151116000241	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1151116000242	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1151116000243	TM-ABC transporter signature motif; other site
1151116000244	HEAT repeats; Region: HEAT_2; pfam13646
1151116000245	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1151116000246	TM-ABC transporter signature motif; other site
1151116000247	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
1151116000248	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
1151116000249	putative ligand binding site [chemical binding]; other site
1151116000250	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1151116000251	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116000252	DNA-binding site [nucleotide binding]; DNA binding site
1151116000253	FCD domain; Region: FCD; pfam07729
1151116000254	urea carboxylase; Region: urea_carbox; TIGR02712
1151116000255	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1151116000256	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1151116000257	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1151116000258	Allophanate hydrolase subunit 2; Region: AHS2; smart00797
1151116000259	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1151116000260	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1151116000261	carboxyltransferase (CT) interaction site; other site
1151116000262	biotinylation site [posttranslational modification]; other site
1151116000263	allophanate hydrolase; Provisional; Region: PRK08186
1151116000264	Amidase; Region: Amidase; cl11426
1151116000265	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1151116000266	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1151116000267	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1151116000268	MarR family; Region: MarR_2; cl17246
1151116000269	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1151116000270	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1151116000271	phosphoethanolamine transferase; Provisional; Region: PRK11560
1151116000272	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1151116000273	Sulfatase; Region: Sulfatase; pfam00884
1151116000274	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
1151116000275	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1151116000276	putative regulator PrlF; Provisional; Region: PRK09974
1151116000277	MmgE/PrpD family; Region: MmgE_PrpD; cl00912
1151116000278	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116000279	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116000280	Walker A/P-loop; other site
1151116000281	ATP binding site [chemical binding]; other site
1151116000282	Q-loop/lid; other site
1151116000283	ABC transporter signature motif; other site
1151116000284	Walker B; other site
1151116000285	D-loop; other site
1151116000286	H-loop/switch region; other site
1151116000287	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116000288	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116000289	Walker A/P-loop; other site
1151116000290	ATP binding site [chemical binding]; other site
1151116000291	Q-loop/lid; other site
1151116000292	ABC transporter signature motif; other site
1151116000293	Walker B; other site
1151116000294	D-loop; other site
1151116000295	H-loop/switch region; other site
1151116000296	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116000297	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116000298	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1151116000299	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116000300	dimer interface [polypeptide binding]; other site
1151116000301	conserved gate region; other site
1151116000302	putative PBP binding loops; other site
1151116000303	ABC-ATPase subunit interface; other site
1151116000304	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116000305	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116000306	dimer interface [polypeptide binding]; other site
1151116000307	conserved gate region; other site
1151116000308	putative PBP binding loops; other site
1151116000309	ABC-ATPase subunit interface; other site
1151116000310	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1151116000311	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1151116000312	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
1151116000313	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1151116000314	putative metal binding site [ion binding]; other site
1151116000315	cell density-dependent motility repressor; Provisional; Region: PRK10082
1151116000316	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116000317	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1151116000318	dimerization interface [polypeptide binding]; other site
1151116000319	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116000320	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1151116000321	peptide binding site [polypeptide binding]; other site
1151116000322	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116000323	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116000324	dimer interface [polypeptide binding]; other site
1151116000325	conserved gate region; other site
1151116000326	putative PBP binding loops; other site
1151116000327	ABC-ATPase subunit interface; other site
1151116000328	dipeptide transporter; Provisional; Region: PRK10913
1151116000329	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1151116000330	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116000331	dimer interface [polypeptide binding]; other site
1151116000332	conserved gate region; other site
1151116000333	putative PBP binding loops; other site
1151116000334	ABC-ATPase subunit interface; other site
1151116000335	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1151116000336	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116000337	Walker A/P-loop; other site
1151116000338	ATP binding site [chemical binding]; other site
1151116000339	Q-loop/lid; other site
1151116000340	ABC transporter signature motif; other site
1151116000341	Walker B; other site
1151116000342	D-loop; other site
1151116000343	H-loop/switch region; other site
1151116000344	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1151116000345	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1151116000346	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116000347	Walker A/P-loop; other site
1151116000348	ATP binding site [chemical binding]; other site
1151116000349	Q-loop/lid; other site
1151116000350	ABC transporter signature motif; other site
1151116000351	Walker B; other site
1151116000352	D-loop; other site
1151116000353	H-loop/switch region; other site
1151116000354	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1151116000355	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116000356	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116000357	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116000358	mobile mystery protein B; Region: mob_myst_B; TIGR02613
1151116000359	Fic/DOC family; Region: Fic; pfam02661
1151116000360	mobile mystery protein A; Region: mob_myst_A; TIGR02612
1151116000361	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116000362	non-specific DNA binding site [nucleotide binding]; other site
1151116000363	salt bridge; other site
1151116000364	sequence-specific DNA binding site [nucleotide binding]; other site
1151116000365	Glycosyl hydrolases family 8; Region: Glyco_hydro_8; cl01351
1151116000366	Cellulose synthase subunit D; Region: Cellsynth_D; pfam03500
1151116000367	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1151116000368	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1151116000369	cellulose synthase regulator protein; Provisional; Region: PRK11114
1151116000370	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1151116000371	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1151116000372	DXD motif; other site
1151116000373	PilZ domain; Region: PilZ; pfam07238
1151116000374	cellulose synthase operon protein YhjQ; Region: cellulose_yhjQ; TIGR03371
1151116000375	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1151116000376	P-loop; other site
1151116000377	Magnesium ion binding site [ion binding]; other site
1151116000378	putative diguanylate cyclase; Provisional; Region: PRK13561
1151116000379	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116000380	metal binding site [ion binding]; metal-binding site
1151116000381	active site
1151116000382	I-site; other site
1151116000383	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116000384	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1151116000385	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1151116000386	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1151116000387	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1151116000388	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1151116000389	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116000390	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1151116000391	substrate binding site [chemical binding]; other site
1151116000392	ATP binding site [chemical binding]; other site
1151116000393	Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [General function prediction only]; Region: COG1942
1151116000394	active site 1 [active]
1151116000395	dimer interface [polypeptide binding]; other site
1151116000396	hexamer interface [polypeptide binding]; other site
1151116000397	active site 2 [active]
1151116000398	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116000399	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1151116000400	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1151116000401	CDP-diacylglycerol pyrophosphatase; Provisional; Region: PRK05471
1151116000402	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116000403	metabolite-proton symporter; Region: 2A0106; TIGR00883
1151116000404	putative substrate translocation pore; other site
1151116000405	inner membrane protein YhjD; Region: TIGR00766
1151116000406	transcriptional regulator; Provisional; Region: PRK10632
1151116000407	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116000408	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1151116000409	putative effector binding pocket; other site
1151116000410	putative dimerization interface [polypeptide binding]; other site
1151116000411	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1151116000412	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116000413	NAD(P) binding site [chemical binding]; other site
1151116000414	active site
1151116000415	Flagellar regulator YcgR; Region: YcgR; pfam07317
1151116000416	PilZ domain; Region: PilZ; pfam07238
1151116000417	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1151116000418	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1151116000419	binding surface
1151116000420	TPR motif; other site
1151116000421	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1151116000422	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1151116000423	DNA binding residues [nucleotide binding]
1151116000424	malate:quinone oxidoreductase; Validated; Region: PRK05257
1151116000425	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1151116000426	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1151116000427	potential frameshift: common BLAST hit: gi|322830860|ref|YP_004210887.1| ImpA domain-containing protein
1151116000428	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1151116000429	Protein of unknown function (DUF3304); Region: DUF3304; pfam11745
1151116000430	Uncharacterized conserved protein (DUF2235); Region: DUF2235; cl01480
1151116000431	Uncharacterized conserved protein (DUF2235); Region: DUF2235; cl01480
1151116000432	malate:quinone oxidoreductase; Validated; Region: PRK05257
1151116000433	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1151116000434	potential frameshift: common BLAST hit: gi|322833018|ref|YP_004213045.1| transposase IS4 family protein
1151116000435	potential frameshift: common BLAST hit: gi|322832437|ref|YP_004212464.1| transposase IS4 family protein
1151116000436	inner membrane transporter YjeM; Provisional; Region: PRK15238
1151116000437	Domain of unknown function (DUF386); Region: DUF386; cl01047
1151116000438	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
1151116000439	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1151116000440	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1151116000441	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1151116000442	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
1151116000443	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
1151116000444	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116000445	DNA binding site [nucleotide binding]
1151116000446	domain linker motif; other site
1151116000447	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
1151116000448	putative dimerization interface [polypeptide binding]; other site
1151116000449	putative ligand binding site [chemical binding]; other site
1151116000450	alpha-glucosidase; Provisional; Region: PRK10137
1151116000451	Protein of unknown function, DUF608; Region: DUF608; pfam04685
1151116000452	Trehalase; Region: Trehalase; cl17346
1151116000453	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1151116000454	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1151116000455	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1151116000456	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1151116000457	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1151116000458	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1151116000459	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1151116000460	active site
1151116000461	Zn binding site [ion binding]; other site
1151116000462	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
1151116000463	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1151116000464	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1151116000465	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1151116000466	DNA binding site [nucleotide binding]
1151116000467	active site
1151116000468	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1151116000469	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1151116000470	tetramer interface [polypeptide binding]; other site
1151116000471	active site
1151116000472	Mg2+/Mn2+ binding site [ion binding]; other site
1151116000473	putative transporter; Provisional; Region: PRK10054
1151116000474	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116000475	putative substrate translocation pore; other site
1151116000476	Uncharacterized conserved protein [Function unknown]; Region: COG4748
1151116000477	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1151116000478	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116000479	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116000480	putative transporter; Provisional; Region: PRK10504
1151116000481	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116000482	putative substrate translocation pore; other site
1151116000483	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116000484	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1151116000485	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1151116000486	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116000487	Walker A/P-loop; other site
1151116000488	ATP binding site [chemical binding]; other site
1151116000489	Q-loop/lid; other site
1151116000490	ABC transporter signature motif; other site
1151116000491	Walker B; other site
1151116000492	D-loop; other site
1151116000493	H-loop/switch region; other site
1151116000494	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
1151116000495	Protein of unknown function, DUF482; Region: DUF482; pfam04339
1151116000496	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1151116000497	active site clefts [active]
1151116000498	zinc binding site [ion binding]; other site
1151116000499	dimer interface [polypeptide binding]; other site
1151116000500	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1151116000501	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1151116000502	active site 1 [active]
1151116000503	dimer interface [polypeptide binding]; other site
1151116000504	hexamer interface [polypeptide binding]; other site
1151116000505	active site 2 [active]
1151116000506	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1151116000507	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1151116000508	active site
1151116000509	P-loop; other site
1151116000510	phosphorylation site [posttranslational modification]
1151116000511	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1151116000512	active site
1151116000513	phosphorylation site [posttranslational modification]
1151116000514	AAA domain; Region: AAA_17; pfam13207
1151116000515	Class I aldolases; Region: Aldolase_Class_I; cl17187
1151116000516	catalytic residue [active]
1151116000517	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1151116000518	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1151116000519	DNA binding residues [nucleotide binding]
1151116000520	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1151116000521	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1151116000522	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1151116000523	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1151116000524	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1151116000525	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1151116000526	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1151116000527	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1151116000528	Isochorismatase family; Region: Isochorismatase; pfam00857
1151116000529	catalytic triad [active]
1151116000530	dimer interface [polypeptide binding]; other site
1151116000531	conserved cis-peptide bond; other site
1151116000532	Predicted membrane protein [Function unknown]; Region: COG2259
1151116000533	Transmembrane secretion effector; Region: MFS_3; pfam05977
1151116000534	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116000535	putative substrate translocation pore; other site
1151116000536	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1151116000537	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116000538	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116000539	dimerization interface [polypeptide binding]; other site
1151116000540	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3224
1151116000541	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1151116000542	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1151116000543	GIY-YIG motif/motif A; other site
1151116000544	active site
1151116000545	catalytic site [active]
1151116000546	putative DNA binding site [nucleotide binding]; other site
1151116000547	metal binding site [ion binding]; metal-binding site
1151116000548	glutathione reductase; Validated; Region: PRK06116
1151116000549	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1151116000550	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1151116000551	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1151116000552	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1151116000553	oligopeptidase A; Provisional; Region: PRK10911
1151116000554	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1151116000555	active site
1151116000556	Zn binding site [ion binding]; other site
1151116000557	putative methyltransferase; Provisional; Region: PRK10742
1151116000558	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1151116000559	Ligand Binding Site [chemical binding]; other site
1151116000560	universal stress protein UspB; Provisional; Region: PRK04960
1151116000561	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1151116000562	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1151116000563	Predicted flavoproteins [General function prediction only]; Region: COG2081
1151116000564	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1151116000565	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1151116000566	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116000567	dimer interface [polypeptide binding]; other site
1151116000568	putative CheW interface [polypeptide binding]; other site
1151116000569	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1151116000570	Beta-lactamase; Region: Beta-lactamase; pfam00144
1151116000571	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
1151116000572	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1151116000573	putative acyl-acceptor binding pocket; other site
1151116000574	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1151116000575	major facilitator superfamily transporter; Provisional; Region: PRK05122
1151116000576	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116000577	putative substrate translocation pore; other site
1151116000578	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1151116000579	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116000580	Coenzyme A binding pocket [chemical binding]; other site
1151116000581	Pirin-related protein [General function prediction only]; Region: COG1741
1151116000582	Pirin; Region: Pirin; pfam02678
1151116000583	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1151116000584	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1151116000585	Autotransporter beta-domain; Region: Autotransporter; smart00869
1151116000586	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1151116000587	active site
1151116000588	P-loop; other site
1151116000589	phosphorylation site [posttranslational modification]
1151116000590	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1151116000591	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1151116000592	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1151116000593	beta-galactosidase; Region: BGL; TIGR03356
1151116000594	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116000595	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116000596	DNA binding site [nucleotide binding]
1151116000597	domain linker motif; other site
1151116000598	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1151116000599	ligand binding site [chemical binding]; other site
1151116000600	dimerization interface [polypeptide binding]; other site
1151116000601	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1151116000602	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116000603	DNA binding site [nucleotide binding]
1151116000604	domain linker motif; other site
1151116000605	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1151116000606	putative ligand binding site [chemical binding]; other site
1151116000607	putative dimerization interface [polypeptide binding]; other site
1151116000608	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1151116000609	ATP-binding site [chemical binding]; other site
1151116000610	Gluconate-6-phosphate binding site [chemical binding]; other site
1151116000611	Shikimate kinase; Region: SKI; pfam01202
1151116000612	high-affinity gluconate transporter; Provisional; Region: PRK14984
1151116000613	gluconate transporter; Region: gntP; TIGR00791
1151116000614	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1151116000615	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116000616	non-specific DNA binding site [nucleotide binding]; other site
1151116000617	salt bridge; other site
1151116000618	sequence-specific DNA binding site [nucleotide binding]; other site
1151116000619	putative antibiotic transporter; Provisional; Region: PRK10739
1151116000620	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1151116000621	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1151116000622	glycogen branching enzyme; Provisional; Region: PRK05402
1151116000623	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1151116000624	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1151116000625	active site
1151116000626	catalytic site [active]
1151116000627	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1151116000628	glycogen debranching enzyme; Provisional; Region: PRK03705
1151116000629	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1151116000630	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1151116000631	active site
1151116000632	catalytic site [active]
1151116000633	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1151116000634	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1151116000635	ligand binding site; other site
1151116000636	oligomer interface; other site
1151116000637	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1151116000638	dimer interface [polypeptide binding]; other site
1151116000639	N-terminal domain interface [polypeptide binding]; other site
1151116000640	sulfate 1 binding site; other site
1151116000641	glycogen synthase; Provisional; Region: glgA; PRK00654
1151116000642	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1151116000643	ADP-binding pocket [chemical binding]; other site
1151116000644	homodimer interface [polypeptide binding]; other site
1151116000645	glycogen phosphorylase; Provisional; Region: PRK14986
1151116000646	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1151116000647	homodimer interface [polypeptide binding]; other site
1151116000648	active site pocket [active]
1151116000649	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1151116000650	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1151116000651	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1151116000652	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1151116000653	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1151116000654	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1151116000655	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1151116000656	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1151116000657	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1151116000658	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1151116000659	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1151116000660	homodimer interface [polypeptide binding]; other site
1151116000661	substrate-cofactor binding pocket; other site
1151116000662	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116000663	catalytic residue [active]
1151116000664	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1151116000665	active site residue [active]
1151116000666	transcriptional repressor UlaR; Provisional; Region: PRK13509
1151116000667	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1151116000668	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1151116000669	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1151116000670	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1151116000671	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1151116000672	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1151116000673	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1151116000674	active site
1151116000675	P-loop; other site
1151116000676	phosphorylation site [posttranslational modification]
1151116000677	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1151116000678	active site
1151116000679	phosphorylation site [posttranslational modification]
1151116000680	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1151116000681	active site
1151116000682	dimer interface [polypeptide binding]; other site
1151116000683	magnesium binding site [ion binding]; other site
1151116000684	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1151116000685	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1151116000686	AP (apurinic/apyrimidinic) site pocket; other site
1151116000687	DNA interaction; other site
1151116000688	Metal-binding active site; metal-binding site
1151116000689	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1151116000690	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1151116000691	intersubunit interface [polypeptide binding]; other site
1151116000692	active site
1151116000693	Zn2+ binding site [ion binding]; other site
1151116000694	maltodextrin phosphorylase; Provisional; Region: PRK14985
1151116000695	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1151116000696	active site pocket [active]
1151116000697	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1151116000698	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1151116000699	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1151116000700	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1151116000701	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1151116000702	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1151116000703	active site
1151116000704	carboxylesterase BioH; Provisional; Region: PRK10349
1151116000705	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116000706	malonate decarboxylase, alpha subunit; Region: mdcA; TIGR01110
1151116000707	Coenzyme A transferase; Region: CoA_trans; cl17247
1151116000708	triphosphoribosyl-dephospho-CoA synthase; Validated; Region: PRK01237
1151116000709	malonate decarboxylase subunit delta; Provisional; Region: PRK01220
1151116000710	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189
1151116000711	malonate decarboxylase, gamma subunit; Region: malonate_gamma; TIGR03134
1151116000712	he Auxin Efflux Carrier (AEC) Family; Region: 2a69; TIGR00946
1151116000713	phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK01293
1151116000714	Phosphoribosyl-dephospho-CoA transferase MdcG; Region: MdcG; pfam10620
1151116000715	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1151116000716	malonate decarboxylase, epsilon subunit; Region: malonate_mdcH; TIGR03131
1151116000717	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
1151116000718	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1151116000719	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116000720	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116000721	The C-terminal substrate-binding domian of LysR-type transcriptional regulator MdcR, which involved in the malonate catabolism contains the type 2 periplasmic binding fold; Region: PBP2_MdcR; cd08416
1151116000722	putative dimerization interface [polypeptide binding]; other site
1151116000723	FeoC like transcriptional regulator; Region: FeoC; cl17677
1151116000724	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1151116000725	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1151116000726	G1 box; other site
1151116000727	GTP/Mg2+ binding site [chemical binding]; other site
1151116000728	Switch I region; other site
1151116000729	G2 box; other site
1151116000730	G3 box; other site
1151116000731	Switch II region; other site
1151116000732	G4 box; other site
1151116000733	G5 box; other site
1151116000734	Nucleoside recognition; Region: Gate; pfam07670
1151116000735	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1151116000736	Nucleoside recognition; Region: Gate; pfam07670
1151116000737	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1151116000738	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1151116000739	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1151116000740	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1151116000741	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1151116000742	RNA binding site [nucleotide binding]; other site
1151116000743	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1151116000744	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1151116000745	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1151116000746	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1151116000747	MG2 domain; Region: A2M_N; pfam01835
1151116000748	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1151116000749	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1151116000750	surface patch; other site
1151116000751	thioester region; other site
1151116000752	specificity defining residues; other site
1151116000753	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
1151116000754	Transglycosylase; Region: Transgly; pfam00912
1151116000755	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1151116000756	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1151116000757	Fimbrial protein; Region: Fimbrial; cl01416
1151116000758	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1151116000759	PapC N-terminal domain; Region: PapC_N; pfam13954
1151116000760	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1151116000761	PapC C-terminal domain; Region: PapC_C; pfam13953
1151116000762	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1151116000763	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1151116000764	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1151116000765	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1151116000766	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1151116000767	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116000768	active site
1151116000769	phosphorylation site [posttranslational modification]
1151116000770	intermolecular recognition site; other site
1151116000771	dimerization interface [polypeptide binding]; other site
1151116000772	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116000773	DNA binding site [nucleotide binding]
1151116000774	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1151116000775	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116000776	dimerization interface [polypeptide binding]; other site
1151116000777	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116000778	dimer interface [polypeptide binding]; other site
1151116000779	phosphorylation site [posttranslational modification]
1151116000780	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116000781	ATP binding site [chemical binding]; other site
1151116000782	G-X-G motif; other site
1151116000783	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1151116000784	oligomeric interface; other site
1151116000785	putative active site [active]
1151116000786	homodimer interface [polypeptide binding]; other site
1151116000787	Plasmid stability protein [General function prediction only]; Region: StbC; COG4691
1151116000788	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1151116000789	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1151116000790	active site
1151116000791	substrate-binding site [chemical binding]; other site
1151116000792	metal-binding site [ion binding]
1151116000793	ATP binding site [chemical binding]; other site
1151116000794	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1151116000795	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1151116000796	dimerization interface [polypeptide binding]; other site
1151116000797	domain crossover interface; other site
1151116000798	redox-dependent activation switch; other site
1151116000799	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1151116000800	RNA binding surface [nucleotide binding]; other site
1151116000801	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1151116000802	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116000803	motif II; other site
1151116000804	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1151116000805	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1151116000806	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1151116000807	ADP-ribose binding site [chemical binding]; other site
1151116000808	dimer interface [polypeptide binding]; other site
1151116000809	active site
1151116000810	nudix motif; other site
1151116000811	metal binding site [ion binding]; metal-binding site
1151116000812	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1151116000813	Transglycosylase; Region: Transgly; pfam00912
1151116000814	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1151116000815	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1151116000816	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1151116000817	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1151116000818	putative outer membrane porin HofQ; Provisional; Region: hofQ; PRK13568
1151116000819	Secretin and TonB N terminus short domain; Region: STN; pfam07660
1151116000820	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1151116000821	shikimate kinase; Reviewed; Region: aroK; PRK00131
1151116000822	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1151116000823	ADP binding site [chemical binding]; other site
1151116000824	magnesium binding site [ion binding]; other site
1151116000825	putative shikimate binding site; other site
1151116000826	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1151116000827	active site
1151116000828	dimer interface [polypeptide binding]; other site
1151116000829	metal binding site [ion binding]; metal-binding site
1151116000830	hypothetical protein; Reviewed; Region: PRK11901
1151116000831	cell division protein DamX; Validated; Region: PRK10905
1151116000832	DNA adenine methylase; Provisional; Region: PRK10904
1151116000833	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1151116000834	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1151116000835	substrate binding site [chemical binding]; other site
1151116000836	hexamer interface [polypeptide binding]; other site
1151116000837	metal binding site [ion binding]; metal-binding site
1151116000838	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1151116000839	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116000840	motif II; other site
1151116000841	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1151116000842	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1151116000843	active site
1151116000844	HIGH motif; other site
1151116000845	dimer interface [polypeptide binding]; other site
1151116000846	KMSKS motif; other site
1151116000847	siroheme synthase; Provisional; Region: cysG; PRK10637
1151116000848	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1151116000849	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1151116000850	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1151116000851	active site
1151116000852	SAM binding site [chemical binding]; other site
1151116000853	homodimer interface [polypeptide binding]; other site
1151116000854	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1151116000855	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1151116000856	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1151116000857	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1151116000858	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1151116000859	cytosine deaminase; Provisional; Region: PRK09230
1151116000860	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1151116000861	active site
1151116000862	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1151116000863	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1151116000864	substrate binding site [chemical binding]; other site
1151116000865	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
1151116000866	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1151116000867	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
1151116000868	active site
1151116000869	catalytic residues [active]
1151116000870	Protein of unknown function (DUF2559); Region: DUF2559; cl08097
1151116000871	Fic/DOC family; Region: Fic; cl00960
1151116000872	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1151116000873	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1151116000874	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1151116000875	glutamine binding [chemical binding]; other site
1151116000876	catalytic triad [active]
1151116000877	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1151116000878	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1151116000879	inhibitor-cofactor binding pocket; inhibition site
1151116000880	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116000881	catalytic residue [active]
1151116000882	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1151116000883	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1151116000884	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1151116000885	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1151116000886	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1151116000887	ligand binding site [chemical binding]; other site
1151116000888	flexible hinge region; other site
1151116000889	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1151116000890	putative switch regulator; other site
1151116000891	non-specific DNA interactions [nucleotide binding]; other site
1151116000892	DNA binding site [nucleotide binding]
1151116000893	sequence specific DNA binding site [nucleotide binding]; other site
1151116000894	putative cAMP binding site [chemical binding]; other site
1151116000895	hypothetical protein; Provisional; Region: PRK10738
1151116000896	phosphoribulokinase; Provisional; Region: PRK15453
1151116000897	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1151116000898	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116000899	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116000900	dimerization interface [polypeptide binding]; other site
1151116000901	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
1151116000902	ureidoglycolate hydrolase; Provisional; Region: PRK03606
1151116000903	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
1151116000904	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1151116000905	Bacterial transcriptional regulator; Region: IclR; pfam01614
1151116000906	glyoxylate carboligase; Provisional; Region: PRK11269
1151116000907	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1151116000908	PYR/PP interface [polypeptide binding]; other site
1151116000909	dimer interface [polypeptide binding]; other site
1151116000910	TPP binding site [chemical binding]; other site
1151116000911	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1151116000912	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
1151116000913	TPP-binding site [chemical binding]; other site
1151116000914	hydroxypyruvate isomerase; Provisional; Region: PRK09997
1151116000915	tartronate semialdehyde reductase; Provisional; Region: PRK15059
1151116000916	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1151116000917	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; solute-binding domain; Region: SLC-NCS1sbd_YbbW-like; cd11485
1151116000918	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1151116000919	Na binding site [ion binding]; other site
1151116000920	putative substrate binding site [chemical binding]; other site
1151116000921	allantoinase; Provisional; Region: PRK08044
1151116000922	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1151116000923	active site
1151116000924	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1151116000925	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1151116000926	putative allantoin catabolism protein; Region: ura-cupin; TIGR03214
1151116000927	Cupin domain; Region: Cupin_2; cl17218
1151116000928	Cupin domain; Region: Cupin_2; cl17218
1151116000929	allantoate amidohydrolase; Region: AllC; TIGR03176
1151116000930	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1151116000931	active site
1151116000932	metal binding site [ion binding]; metal-binding site
1151116000933	dimer interface [polypeptide binding]; other site
1151116000934	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
1151116000935	membrane protein FdrA; Validated; Region: PRK06091
1151116000936	CoA binding domain; Region: CoA_binding; pfam02629
1151116000937	CoA-ligase; Region: Ligase_CoA; pfam00549
1151116000938	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1151116000939	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1151116000940	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1151116000941	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1151116000942	putative substrate binding site [chemical binding]; other site
1151116000943	nucleotide binding site [chemical binding]; other site
1151116000944	nucleotide binding site [chemical binding]; other site
1151116000945	homodimer interface [polypeptide binding]; other site
1151116000946	hypothetical protein; Provisional; Region: PRK04966
1151116000947	putative hydrolase; Provisional; Region: PRK10985
1151116000948	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1151116000949	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1151116000950	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116000951	Walker A/P-loop; other site
1151116000952	ATP binding site [chemical binding]; other site
1151116000953	Q-loop/lid; other site
1151116000954	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116000955	ABC transporter signature motif; other site
1151116000956	Walker B; other site
1151116000957	D-loop; other site
1151116000958	ABC transporter; Region: ABC_tran_2; pfam12848
1151116000959	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116000960	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1151116000961	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1151116000962	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1151116000963	TrkA-N domain; Region: TrkA_N; pfam02254
1151116000964	Probable metal-binding protein (DUF2387); Region: DUF2387; pfam09526
1151116000965	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1151116000966	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1151116000967	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116000968	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116000969	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116000970	phi X174 lysis protein; Provisional; Region: PRK02793
1151116000971	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1151116000972	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1151116000973	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1151116000974	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1151116000975	YheO-like PAS domain; Region: PAS_6; pfam08348
1151116000976	HTH domain; Region: HTH_22; pfam13309
1151116000977	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1151116000978	sulfur relay protein TusC; Validated; Region: PRK00211
1151116000979	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1151116000980	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1151116000981	S17 interaction site [polypeptide binding]; other site
1151116000982	S8 interaction site; other site
1151116000983	16S rRNA interaction site [nucleotide binding]; other site
1151116000984	streptomycin interaction site [chemical binding]; other site
1151116000985	23S rRNA interaction site [nucleotide binding]; other site
1151116000986	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1151116000987	30S ribosomal protein S7; Validated; Region: PRK05302
1151116000988	elongation factor G; Reviewed; Region: PRK00007
1151116000989	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1151116000990	G1 box; other site
1151116000991	putative GEF interaction site [polypeptide binding]; other site
1151116000992	GTP/Mg2+ binding site [chemical binding]; other site
1151116000993	Switch I region; other site
1151116000994	G2 box; other site
1151116000995	G3 box; other site
1151116000996	Switch II region; other site
1151116000997	G4 box; other site
1151116000998	G5 box; other site
1151116000999	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1151116001000	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1151116001001	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1151116001002	elongation factor Tu; Reviewed; Region: PRK00049
1151116001003	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1151116001004	G1 box; other site
1151116001005	GEF interaction site [polypeptide binding]; other site
1151116001006	GTP/Mg2+ binding site [chemical binding]; other site
1151116001007	Switch I region; other site
1151116001008	G2 box; other site
1151116001009	G3 box; other site
1151116001010	Switch II region; other site
1151116001011	G4 box; other site
1151116001012	G5 box; other site
1151116001013	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1151116001014	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1151116001015	Antibiotic Binding Site [chemical binding]; other site
1151116001016	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1151116001017	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1151116001018	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1151116001019	heme binding site [chemical binding]; other site
1151116001020	ferroxidase pore; other site
1151116001021	ferroxidase diiron center [ion binding]; other site
1151116001022	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1151116001023	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1151116001024	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
1151116001025	potential frameshift: common BLAST hit: gi|322831059|ref|YP_004211086.1| general secretion pathway protein L
1151116001026	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
1151116001027	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1151116001028	type II secretion system protein J; Region: gspJ; TIGR01711
1151116001029	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
1151116001030	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1151116001031	type II secretion system protein I; Region: gspI; TIGR01707
1151116001032	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
1151116001033	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
1151116001034	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1151116001035	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
1151116001036	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
1151116001037	type II secretion system protein F; Region: GspF; TIGR02120
1151116001038	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1151116001039	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1151116001040	type II secretion system protein E; Region: type_II_gspE; TIGR02533
1151116001041	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1151116001042	Walker A motif; other site
1151116001043	ATP binding site [chemical binding]; other site
1151116001044	Walker B motif; other site
1151116001045	type II secretion system protein D; Region: type_II_gspD; TIGR02517
1151116001046	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1151116001047	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1151116001048	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1151116001049	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1151116001050	type II secretion system protein C; Region: typeII_sec_gspC; TIGR01713
1151116001051	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
1151116001052	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1151116001053	putative secretion ATPase, PEP-CTERM locus subfamily; Region: pepcterm_ATPase; TIGR03015
1151116001054	AAA ATPase domain; Region: AAA_16; pfam13191
1151116001055	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1151116001056	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1151116001057	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1151116001058	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1151116001059	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1151116001060	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1151116001061	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1151116001062	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1151116001063	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1151116001064	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1151116001065	protein-rRNA interface [nucleotide binding]; other site
1151116001066	putative translocon binding site; other site
1151116001067	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1151116001068	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1151116001069	G-X-X-G motif; other site
1151116001070	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1151116001071	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1151116001072	23S rRNA interface [nucleotide binding]; other site
1151116001073	5S rRNA interface [nucleotide binding]; other site
1151116001074	putative antibiotic binding site [chemical binding]; other site
1151116001075	L25 interface [polypeptide binding]; other site
1151116001076	L27 interface [polypeptide binding]; other site
1151116001077	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1151116001078	23S rRNA interface [nucleotide binding]; other site
1151116001079	putative translocon interaction site; other site
1151116001080	signal recognition particle (SRP54) interaction site; other site
1151116001081	L23 interface [polypeptide binding]; other site
1151116001082	trigger factor interaction site; other site
1151116001083	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1151116001084	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1151116001085	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1151116001086	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1151116001087	RNA binding site [nucleotide binding]; other site
1151116001088	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1151116001089	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1151116001090	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1151116001091	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1151116001092	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1151116001093	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1151116001094	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1151116001095	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1151116001096	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1151116001097	23S rRNA interface [nucleotide binding]; other site
1151116001098	5S rRNA interface [nucleotide binding]; other site
1151116001099	L27 interface [polypeptide binding]; other site
1151116001100	L5 interface [polypeptide binding]; other site
1151116001101	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1151116001102	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1151116001103	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1151116001104	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1151116001105	23S rRNA binding site [nucleotide binding]; other site
1151116001106	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1151116001107	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1151116001108	SecY translocase; Region: SecY; pfam00344
1151116001109	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1151116001110	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1151116001111	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1151116001112	30S ribosomal protein S11; Validated; Region: PRK05309
1151116001113	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1151116001114	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1151116001115	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1151116001116	RNA binding surface [nucleotide binding]; other site
1151116001117	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1151116001118	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1151116001119	alphaNTD homodimer interface [polypeptide binding]; other site
1151116001120	alphaNTD - beta interaction site [polypeptide binding]; other site
1151116001121	alphaNTD - beta' interaction site [polypeptide binding]; other site
1151116001122	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1151116001123	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1151116001124	hypothetical protein; Provisional; Region: PRK10203
1151116001125	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1151116001126	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1151116001127	DNA binding residues [nucleotide binding]
1151116001128	dimer interface [polypeptide binding]; other site
1151116001129	metal binding site [ion binding]; metal-binding site
1151116001130	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1151116001131	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1151116001132	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1151116001133	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1151116001134	TrkA-N domain; Region: TrkA_N; pfam02254
1151116001135	TrkA-C domain; Region: TrkA_C; pfam02080
1151116001136	TrkA-N domain; Region: TrkA_N; pfam02254
1151116001137	TrkA-C domain; Region: TrkA_C; pfam02080
1151116001138	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1151116001139	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1151116001140	putative RNA binding site [nucleotide binding]; other site
1151116001141	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116001142	S-adenosylmethionine binding site [chemical binding]; other site
1151116001143	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1151116001144	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1151116001145	putative active site [active]
1151116001146	substrate binding site [chemical binding]; other site
1151116001147	putative cosubstrate binding site; other site
1151116001148	catalytic site [active]
1151116001149	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1151116001150	substrate binding site [chemical binding]; other site
1151116001151	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1151116001152	active site
1151116001153	catalytic residues [active]
1151116001154	metal binding site [ion binding]; metal-binding site
1151116001155	hypothetical protein; Provisional; Region: PRK10736
1151116001156	DNA protecting protein DprA; Region: dprA; TIGR00732
1151116001157	hypothetical protein; Validated; Region: PRK03430
1151116001158	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1151116001159	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1151116001160	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1151116001161	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1151116001162	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1151116001163	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1151116001164	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1151116001165	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1151116001166	shikimate binding site; other site
1151116001167	NAD(P) binding site [chemical binding]; other site
1151116001168	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1151116001169	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1151116001170	trimer interface [polypeptide binding]; other site
1151116001171	putative metal binding site [ion binding]; other site
1151116001172	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1151116001173	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1151116001174	Na binding site [ion binding]; other site
1151116001175	Predicted membrane protein [Function unknown]; Region: COG3162
1151116001176	acetyl-CoA synthetase; Provisional; Region: PRK00174
1151116001177	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1151116001178	active site
1151116001179	CoA binding site [chemical binding]; other site
1151116001180	acyl-activating enzyme (AAE) consensus motif; other site
1151116001181	AMP binding site [chemical binding]; other site
1151116001182	acetate binding site [chemical binding]; other site
1151116001183	Fimbrial protein; Region: Fimbrial; cl01416
1151116001184	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
1151116001185	PapC N-terminal domain; Region: PapC_N; pfam13954
1151116001186	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1151116001187	PapC C-terminal domain; Region: PapC_C; pfam13953
1151116001188	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1151116001189	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1151116001190	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1151116001191	Fimbrial protein; Region: Fimbrial; pfam00419
1151116001192	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116001193	non-specific DNA binding site [nucleotide binding]; other site
1151116001194	salt bridge; other site
1151116001195	sequence-specific DNA binding site [nucleotide binding]; other site
1151116001196	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1151116001197	DNA binding site [nucleotide binding]
1151116001198	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1151116001199	putative dimer interface [polypeptide binding]; other site
1151116001200	catalytic triad [active]
1151116001201	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116001202	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116001203	putative substrate translocation pore; other site
1151116001204	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1151116001205	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1151116001206	active site pocket [active]
1151116001207	putative transcriptional regulator; Provisional; Region: PRK11640
1151116001208	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1151116001209	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1151116001210	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1151116001211	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1151116001212	DsbD alpha interface [polypeptide binding]; other site
1151116001213	catalytic residues [active]
1151116001214	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1151116001215	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1151116001216	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1151116001217	Aspartase; Region: Aspartase; cd01357
1151116001218	active sites [active]
1151116001219	tetramer interface [polypeptide binding]; other site
1151116001220	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1151116001221	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1151116001222	oligomerisation interface [polypeptide binding]; other site
1151116001223	mobile loop; other site
1151116001224	roof hairpin; other site
1151116001225	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1151116001226	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1151116001227	ring oligomerisation interface [polypeptide binding]; other site
1151116001228	ATP/Mg binding site [chemical binding]; other site
1151116001229	stacking interactions; other site
1151116001230	hinge regions; other site
1151116001231	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1151116001232	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1151116001233	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116001234	FeS/SAM binding site; other site
1151116001235	elongation factor P; Validated; Region: PRK00529
1151116001236	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1151116001237	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1151116001238	RNA binding site [nucleotide binding]; other site
1151116001239	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1151116001240	RNA binding site [nucleotide binding]; other site
1151116001241	entericidin A; Provisional; Region: PRK09810
1151116001242	Entericidin EcnA/B family; Region: Entericidin; cl02322
1151116001243	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1151116001244	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1151116001245	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1151116001246	Iron-sulfur protein interface; other site
1151116001247	proximal quinone binding site [chemical binding]; other site
1151116001248	C-subunit interface; other site
1151116001249	distal quinone binding site; other site
1151116001250	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1151116001251	D-subunit interface [polypeptide binding]; other site
1151116001252	Iron-sulfur protein interface; other site
1151116001253	proximal quinone binding site [chemical binding]; other site
1151116001254	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1151116001255	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1151116001256	catalytic loop [active]
1151116001257	iron binding site [ion binding]; other site
1151116001258	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1151116001259	L-aspartate oxidase; Provisional; Region: PRK06175
1151116001260	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1151116001261	poxB regulator PoxA; Provisional; Region: PRK09350
1151116001262	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1151116001263	motif 1; other site
1151116001264	dimer interface [polypeptide binding]; other site
1151116001265	active site
1151116001266	motif 2; other site
1151116001267	motif 3; other site
1151116001268	xanthine permease; Region: pbuX; TIGR03173
1151116001269	hydroxydechloroatrazine ethylaminohydrolase; Reviewed; Region: PRK08203
1151116001270	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1151116001271	active site
1151116001272	putative substrate binding pocket [chemical binding]; other site
1151116001273	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1151116001274	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1151116001275	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1151116001276	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1151116001277	GTPase RsgA; Reviewed; Region: PRK12288
1151116001278	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1151116001279	RNA binding site [nucleotide binding]; other site
1151116001280	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1151116001281	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1151116001282	GTP/Mg2+ binding site [chemical binding]; other site
1151116001283	G4 box; other site
1151116001284	G5 box; other site
1151116001285	G1 box; other site
1151116001286	Switch I region; other site
1151116001287	G2 box; other site
1151116001288	G3 box; other site
1151116001289	Switch II region; other site
1151116001290	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1151116001291	catalytic site [active]
1151116001292	putative active site [active]
1151116001293	putative substrate binding site [chemical binding]; other site
1151116001294	dimer interface [polypeptide binding]; other site
1151116001295	epoxyqueuosine reductase; Region: TIGR00276
1151116001296	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1151116001297	putative carbohydrate kinase; Provisional; Region: PRK10565
1151116001298	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1151116001299	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1151116001300	putative substrate binding site [chemical binding]; other site
1151116001301	putative ATP binding site [chemical binding]; other site
1151116001302	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; cl00520
1151116001303	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1151116001304	AMIN domain; Region: AMIN; pfam11741
1151116001305	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1151116001306	active site
1151116001307	metal binding site [ion binding]; metal-binding site
1151116001308	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1151116001309	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1151116001310	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1151116001311	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116001312	ATP binding site [chemical binding]; other site
1151116001313	Mg2+ binding site [ion binding]; other site
1151116001314	G-X-G motif; other site
1151116001315	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1151116001316	ATP binding site [chemical binding]; other site
1151116001317	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1151116001318	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1151116001319	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1151116001320	bacterial Hfq-like; Region: Hfq; cd01716
1151116001321	hexamer interface [polypeptide binding]; other site
1151116001322	Sm1 motif; other site
1151116001323	RNA binding site [nucleotide binding]; other site
1151116001324	Sm2 motif; other site
1151116001325	GTPase HflX; Provisional; Region: PRK11058
1151116001326	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1151116001327	HflX GTPase family; Region: HflX; cd01878
1151116001328	G1 box; other site
1151116001329	GTP/Mg2+ binding site [chemical binding]; other site
1151116001330	Switch I region; other site
1151116001331	G2 box; other site
1151116001332	G3 box; other site
1151116001333	Switch II region; other site
1151116001334	G4 box; other site
1151116001335	G5 box; other site
1151116001336	FtsH protease regulator HflK; Provisional; Region: PRK10930
1151116001337	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1151116001338	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1151116001339	FtsH protease regulator HflC; Provisional; Region: PRK11029
1151116001340	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1151116001341	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1151116001342	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1151116001343	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1151116001344	GDP-binding site [chemical binding]; other site
1151116001345	ACT binding site; other site
1151116001346	IMP binding site; other site
1151116001347	transcriptional repressor NsrR; Provisional; Region: PRK11014
1151116001348	Rrf2 family protein; Region: rrf2_super; TIGR00738
1151116001349	exoribonuclease R; Provisional; Region: PRK11642
1151116001350	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
1151116001351	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1151116001352	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1151116001353	RNB domain; Region: RNB; pfam00773
1151116001354	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1151116001355	RNA binding site [nucleotide binding]; other site
1151116001356	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1151116001357	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1151116001358	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1151116001359	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1151116001360	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1151116001361	FAD binding site [chemical binding]; other site
1151116001362	substrate binding site [chemical binding]; other site
1151116001363	catalytic residues [active]
1151116001364	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1151116001365	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116001366	dimerization interface [polypeptide binding]; other site
1151116001367	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1151116001368	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116001369	dimer interface [polypeptide binding]; other site
1151116001370	putative CheW interface [polypeptide binding]; other site
1151116001371	esterase; Provisional; Region: PRK10566
1151116001372	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1151116001373	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1151116001374	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1151116001375	dimer interface [polypeptide binding]; other site
1151116001376	ssDNA binding site [nucleotide binding]; other site
1151116001377	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1151116001378	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1151116001379	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1151116001380	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1151116001381	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1151116001382	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1151116001383	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1151116001384	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1151116001385	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1151116001386	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1151116001387	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1151116001388	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1151116001389	Hemerythrin-like domain; Region: Hr-like; cd12108
1151116001390	Fe binding site [ion binding]; other site
1151116001391	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1151116001392	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1151116001393	active site
1151116001394	metal binding site [ion binding]; metal-binding site
1151116001395	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1151116001396	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1151116001397	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1151116001398	active site
1151116001399	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; cl17398
1151116001400	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1151116001401	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1151116001402	Domain of unknown function DUF21; Region: DUF21; pfam01595
1151116001403	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1151116001404	Transporter associated domain; Region: CorC_HlyC; smart01091
1151116001405	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1151116001406	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1151116001407	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116001408	Surface antigen; Region: Bac_surface_Ag; pfam01103
1151116001409	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1151116001410	Family of unknown function (DUF490); Region: DUF490; pfam04357
1151116001411	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1151116001412	putative active site pocket [active]
1151116001413	dimerization interface [polypeptide binding]; other site
1151116001414	putative catalytic residue [active]
1151116001415	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1151116001416	dimer interface [polypeptide binding]; other site
1151116001417	substrate binding site [chemical binding]; other site
1151116001418	metal binding sites [ion binding]; metal-binding site
1151116001419	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1151116001420	dimer interface [polypeptide binding]; other site
1151116001421	ligand binding site [chemical binding]; other site
1151116001422	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1151116001423	HAMP domain; Region: HAMP; pfam00672
1151116001424	dimerization interface [polypeptide binding]; other site
1151116001425	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116001426	dimer interface [polypeptide binding]; other site
1151116001427	putative CheW interface [polypeptide binding]; other site
1151116001428	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1151116001429	AMP binding site [chemical binding]; other site
1151116001430	metal binding site [ion binding]; metal-binding site
1151116001431	active site
1151116001432	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1151116001433	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1151116001434	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1151116001435	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1151116001436	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116001437	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116001438	arginine repressor; Provisional; Region: PRK05066
1151116001439	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1151116001440	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1151116001441	malate dehydrogenase; Provisional; Region: PRK05086
1151116001442	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1151116001443	NAD binding site [chemical binding]; other site
1151116001444	dimerization interface [polypeptide binding]; other site
1151116001445	Substrate binding site [chemical binding]; other site
1151116001446	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1151116001447	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
1151116001448	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1151116001449	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1151116001450	substrate binding pocket [chemical binding]; other site
1151116001451	chain length determination region; other site
1151116001452	substrate-Mg2+ binding site; other site
1151116001453	catalytic residues [active]
1151116001454	aspartate-rich region 1; other site
1151116001455	active site lid residues [active]
1151116001456	aspartate-rich region 2; other site
1151116001457	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1151116001458	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1151116001459	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1151116001460	EamA-like transporter family; Region: EamA; pfam00892
1151116001461	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1151116001462	GTP1/OBG; Region: GTP1_OBG; pfam01018
1151116001463	Obg GTPase; Region: Obg; cd01898
1151116001464	G1 box; other site
1151116001465	GTP/Mg2+ binding site [chemical binding]; other site
1151116001466	Switch I region; other site
1151116001467	G2 box; other site
1151116001468	G3 box; other site
1151116001469	Switch II region; other site
1151116001470	G4 box; other site
1151116001471	G5 box; other site
1151116001472	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116001473	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116001474	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116001475	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1151116001476	HAMP domain; Region: HAMP; pfam00672
1151116001477	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116001478	dimer interface [polypeptide binding]; other site
1151116001479	phosphorylation site [posttranslational modification]
1151116001480	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116001481	ATP binding site [chemical binding]; other site
1151116001482	Mg2+ binding site [ion binding]; other site
1151116001483	G-X-G motif; other site
1151116001484	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1151116001485	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116001486	active site
1151116001487	phosphorylation site [posttranslational modification]
1151116001488	intermolecular recognition site; other site
1151116001489	dimerization interface [polypeptide binding]; other site
1151116001490	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116001491	DNA binding site [nucleotide binding]
1151116001492	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1151116001493	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1151116001494	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1151116001495	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1151116001496	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1151116001497	RNA-binding protein YhbY; Provisional; Region: PRK10343
1151116001498	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1151116001499	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116001500	S-adenosylmethionine binding site [chemical binding]; other site
1151116001501	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1151116001502	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116001503	Walker A motif; other site
1151116001504	ATP binding site [chemical binding]; other site
1151116001505	Walker B motif; other site
1151116001506	arginine finger; other site
1151116001507	Peptidase family M41; Region: Peptidase_M41; pfam01434
1151116001508	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1151116001509	dihydropteroate synthase; Region: DHPS; TIGR01496
1151116001510	substrate binding pocket [chemical binding]; other site
1151116001511	dimer interface [polypeptide binding]; other site
1151116001512	inhibitor binding site; inhibition site
1151116001513	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1151116001514	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1151116001515	active site
1151116001516	substrate binding site [chemical binding]; other site
1151116001517	metal binding site [ion binding]; metal-binding site
1151116001518	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1151116001519	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1151116001520	Sm and related proteins; Region: Sm_like; cl00259
1151116001521	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1151116001522	putative oligomer interface [polypeptide binding]; other site
1151116001523	putative RNA binding site [nucleotide binding]; other site
1151116001524	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1151116001525	NusA N-terminal domain; Region: NusA_N; pfam08529
1151116001526	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1151116001527	RNA binding site [nucleotide binding]; other site
1151116001528	homodimer interface [polypeptide binding]; other site
1151116001529	NusA-like KH domain; Region: KH_5; pfam13184
1151116001530	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1151116001531	G-X-X-G motif; other site
1151116001532	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1151116001533	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1151116001534	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1151116001535	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1151116001536	translation initiation factor IF-2; Validated; Region: infB; PRK05306
1151116001537	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1151116001538	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1151116001539	G1 box; other site
1151116001540	putative GEF interaction site [polypeptide binding]; other site
1151116001541	GTP/Mg2+ binding site [chemical binding]; other site
1151116001542	Switch I region; other site
1151116001543	G2 box; other site
1151116001544	G3 box; other site
1151116001545	Switch II region; other site
1151116001546	G4 box; other site
1151116001547	G5 box; other site
1151116001548	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1151116001549	Translation-initiation factor 2; Region: IF-2; pfam11987
1151116001550	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1151116001551	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1151116001552	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1151116001553	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1151116001554	RNA binding site [nucleotide binding]; other site
1151116001555	active site
1151116001556	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1151116001557	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1151116001558	16S/18S rRNA binding site [nucleotide binding]; other site
1151116001559	S13e-L30e interaction site [polypeptide binding]; other site
1151116001560	25S rRNA binding site [nucleotide binding]; other site
1151116001561	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1151116001562	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1151116001563	RNase E interface [polypeptide binding]; other site
1151116001564	trimer interface [polypeptide binding]; other site
1151116001565	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1151116001566	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1151116001567	RNase E interface [polypeptide binding]; other site
1151116001568	trimer interface [polypeptide binding]; other site
1151116001569	active site
1151116001570	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1151116001571	putative nucleic acid binding region [nucleotide binding]; other site
1151116001572	G-X-X-G motif; other site
1151116001573	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1151116001574	RNA binding site [nucleotide binding]; other site
1151116001575	domain interface; other site
1151116001576	lipoprotein NlpI; Provisional; Region: PRK11189
1151116001577	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1151116001578	binding surface
1151116001579	TPR motif; other site
1151116001580	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1151116001581	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1151116001582	ATP binding site [chemical binding]; other site
1151116001583	Mg++ binding site [ion binding]; other site
1151116001584	motif III; other site
1151116001585	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116001586	nucleotide binding region [chemical binding]; other site
1151116001587	ATP-binding site [chemical binding]; other site
1151116001588	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1151116001589	putative RNA binding site [nucleotide binding]; other site
1151116001590	hypothetical protein; Provisional; Region: PRK10508
1151116001591	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
1151116001592	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1151116001593	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1151116001594	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116001595	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116001596	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1151116001597	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1151116001598	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1151116001599	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1151116001600	putative protease; Provisional; Region: PRK15447
1151116001601	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1151116001602	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1151116001603	Peptidase family U32; Region: Peptidase_U32; pfam01136
1151116001604	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1151116001605	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116001606	Coenzyme A binding pocket [chemical binding]; other site
1151116001607	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1151116001608	putative active site [active]
1151116001609	GIY-YIG motif/motif A; other site
1151116001610	putative metal binding site [ion binding]; other site
1151116001611	hypothetical protein; Provisional; Region: PRK03467
1151116001612	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1151116001613	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1151116001614	NAD binding site [chemical binding]; other site
1151116001615	active site
1151116001616	phosphonate metabolim protein, transferase hexapeptide repeat family; Region: phn_thr-fam; TIGR03308
1151116001617	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1151116001618	trimer interface [polypeptide binding]; other site
1151116001619	active site
1151116001620	substrate binding site [chemical binding]; other site
1151116001621	CoA binding site [chemical binding]; other site
1151116001622	Guanylate kinase; Region: Guanylate_kin; pfam00625
1151116001623	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1151116001624	active site
1151116001625	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
1151116001626	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1151116001627	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
1151116001628	active site
1151116001629	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
1151116001630	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1151116001631	Walker A/P-loop; other site
1151116001632	ATP binding site [chemical binding]; other site
1151116001633	Q-loop/lid; other site
1151116001634	ABC transporter signature motif; other site
1151116001635	Walker B; other site
1151116001636	D-loop; other site
1151116001637	H-loop/switch region; other site
1151116001638	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
1151116001639	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116001640	Walker A/P-loop; other site
1151116001641	ATP binding site [chemical binding]; other site
1151116001642	Q-loop/lid; other site
1151116001643	ABC transporter signature motif; other site
1151116001644	Walker B; other site
1151116001645	D-loop; other site
1151116001646	H-loop/switch region; other site
1151116001647	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116001648	Phosphonate metabolism protein PhnJ; Region: PhnJ; pfam06007
1151116001649	Bacterial phosphonate metabolism protein (PhnI); Region: PhnI; pfam05861
1151116001650	carbon-phosphorus lyase complex subunit; Validated; Region: phnH; PRK10147
1151116001651	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
1151116001652	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
1151116001653	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116001654	DNA-binding site [nucleotide binding]; DNA binding site
1151116001655	UTRA domain; Region: UTRA; pfam07702
1151116001656	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1151116001657	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116001658	non-specific DNA binding site [nucleotide binding]; other site
1151116001659	salt bridge; other site
1151116001660	sequence-specific DNA binding site [nucleotide binding]; other site
1151116001661	Post-segregation antitoxin CcdA; Region: CcdA; cl02188
1151116001662	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; PRK11121
1151116001663	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
1151116001664	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1151116001665	ATP cone domain; Region: ATP-cone; pfam03477
1151116001666	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1151116001667	effector binding site; other site
1151116001668	active site
1151116001669	Zn binding site [ion binding]; other site
1151116001670	glycine loop; other site
1151116001671	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1151116001672	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1151116001673	Ca binding site [ion binding]; other site
1151116001674	active site
1151116001675	catalytic site [active]
1151116001676	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1151116001677	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1151116001678	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116001679	active site turn [active]
1151116001680	phosphorylation site [posttranslational modification]
1151116001681	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116001682	trehalose repressor; Provisional; Region: treR; PRK09492
1151116001683	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116001684	DNA binding site [nucleotide binding]
1151116001685	domain linker motif; other site
1151116001686	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1151116001687	dimerization interface [polypeptide binding]; other site
1151116001688	ligand binding site [chemical binding]; other site
1151116001689	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1151116001690	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1151116001691	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1151116001692	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1151116001693	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1151116001694	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1151116001695	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1151116001696	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1151116001697	catalytic triad [active]
1151116001698	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1151116001699	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1151116001700	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1151116001701	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1151116001702	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1151116001703	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116001704	S-adenosylmethionine binding site [chemical binding]; other site
1151116001705	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1151116001706	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1151116001707	active site
1151116001708	FMN binding site [chemical binding]; other site
1151116001709	2,4-decadienoyl-CoA binding site; other site
1151116001710	catalytic residue [active]
1151116001711	4Fe-4S cluster binding site [ion binding]; other site
1151116001712	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1151116001713	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1151116001714	enoyl-CoA hydratase; Validated; Region: PRK08788
1151116001715	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1151116001716	substrate binding site [chemical binding]; other site
1151116001717	oxyanion hole (OAH) forming residues; other site
1151116001718	trimer interface [polypeptide binding]; other site
1151116001719	RNase II stability modulator; Provisional; Region: PRK10060
1151116001720	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116001721	putative active site [active]
1151116001722	heme pocket [chemical binding]; other site
1151116001723	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116001724	metal binding site [ion binding]; metal-binding site
1151116001725	active site
1151116001726	I-site; other site
1151116001727	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116001728	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1151116001729	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1151116001730	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1151116001731	transcriptional regulator MalT; Provisional; Region: PRK04841
1151116001732	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116001733	DNA binding residues [nucleotide binding]
1151116001734	dimerization interface [polypeptide binding]; other site
1151116001735	maltodextrin phosphorylase; Provisional; Region: PRK14985
1151116001736	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1151116001737	active site pocket [active]
1151116001738	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1151116001739	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1151116001740	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116001741	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116001742	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116001743	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116001744	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116001745	dimer interface [polypeptide binding]; other site
1151116001746	conserved gate region; other site
1151116001747	putative PBP binding loops; other site
1151116001748	ABC-ATPase subunit interface; other site
1151116001749	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116001750	dimer interface [polypeptide binding]; other site
1151116001751	conserved gate region; other site
1151116001752	putative PBP binding loops; other site
1151116001753	ABC-ATPase subunit interface; other site
1151116001754	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1151116001755	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1151116001756	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1151116001757	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1151116001758	Walker A/P-loop; other site
1151116001759	ATP binding site [chemical binding]; other site
1151116001760	Q-loop/lid; other site
1151116001761	ABC transporter signature motif; other site
1151116001762	Walker B; other site
1151116001763	D-loop; other site
1151116001764	H-loop/switch region; other site
1151116001765	TOBE domain; Region: TOBE_2; pfam08402
1151116001766	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1151116001767	trimer interface; other site
1151116001768	sugar binding site [chemical binding]; other site
1151116001769	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1151116001770	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1151116001771	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116001772	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116001773	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116001774	Protein of unknown function (DUF2000); Region: DUF2000; cl02074
1151116001775	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1151116001776	active site
1151116001777	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1151116001778	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1151116001779	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1151116001780	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1151116001781	DNA binding site [nucleotide binding]
1151116001782	active site
1151116001783	glutamate dehydrogenase; Provisional; Region: PRK09414
1151116001784	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1151116001785	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1151116001786	NAD(P) binding site [chemical binding]; other site
1151116001787	outer membrane receptor FepA; Provisional; Region: PRK13524
1151116001788	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116001789	N-terminal plug; other site
1151116001790	ligand-binding site [chemical binding]; other site
1151116001791	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1151116001792	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1151116001793	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1151116001794	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1151116001795	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1151116001796	Walker A/P-loop; other site
1151116001797	ATP binding site [chemical binding]; other site
1151116001798	Q-loop/lid; other site
1151116001799	ABC transporter signature motif; other site
1151116001800	Walker B; other site
1151116001801	D-loop; other site
1151116001802	H-loop/switch region; other site
1151116001803	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1151116001804	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116001805	ABC-ATPase subunit  interface; other site
1151116001806	dimer interface [polypeptide binding]; other site
1151116001807	putative PBP binding regions; other site
1151116001808	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1151116001809	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1151116001810	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116001811	ABC-ATPase subunit  interface; other site
1151116001812	dimer interface [polypeptide binding]; other site
1151116001813	putative PBP binding regions; other site
1151116001814	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1151116001815	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1151116001816	siderophore binding site; other site
1151116001817	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1151116001818	active site
1151116001819	SUMO-1 interface [polypeptide binding]; other site
1151116001820	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1151116001821	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1151116001822	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1151116001823	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1151116001824	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1151116001825	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1151116001826	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1151116001827	DNA binding residues [nucleotide binding]
1151116001828	DNA primase; Validated; Region: dnaG; PRK05667
1151116001829	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1151116001830	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1151116001831	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1151116001832	active site
1151116001833	metal binding site [ion binding]; metal-binding site
1151116001834	interdomain interaction site; other site
1151116001835	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1151116001836	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1151116001837	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1151116001838	UGMP family protein; Validated; Region: PRK09604
1151116001839	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1151116001840	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1151116001841	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1151116001842	homooctamer interface [polypeptide binding]; other site
1151116001843	active site
1151116001844	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1151116001845	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1151116001846	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1151116001847	active site
1151116001848	NTP binding site [chemical binding]; other site
1151116001849	metal binding triad [ion binding]; metal-binding site
1151116001850	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1151116001851	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1151116001852	Zn2+ binding site [ion binding]; other site
1151116001853	Mg2+ binding site [ion binding]; other site
1151116001854	SH3 domain-containing protein; Provisional; Region: PRK10884
1151116001855	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1151116001856	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1151116001857	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1151116001858	putative active site [active]
1151116001859	putative metal binding residues [ion binding]; other site
1151116001860	signature motif; other site
1151116001861	putative triphosphate binding site [ion binding]; other site
1151116001862	The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family; Region: CHAD; smart00880
1151116001863	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1151116001864	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1151116001865	metal binding triad; other site
1151116001866	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1151116001867	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1151116001868	metal binding triad; other site
1151116001869	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1151116001870	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116001871	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1151116001872	putative ribose interaction site [chemical binding]; other site
1151116001873	putative ADP binding site [chemical binding]; other site
1151116001874	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1151116001875	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1151116001876	active site
1151116001877	nucleotide binding site [chemical binding]; other site
1151116001878	HIGH motif; other site
1151116001879	KMSKS motif; other site
1151116001880	putative transporter; Provisional; Region: PRK11021
1151116001881	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1151116001882	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1151116001883	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1151116001884	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1151116001885	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1151116001886	putative active site [active]
1151116001887	metal binding site [ion binding]; metal-binding site
1151116001888	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1151116001889	hypothetical protein; Provisional; Region: PRK11653
1151116001890	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1151116001891	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1151116001892	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1151116001893	dimer interface [polypeptide binding]; other site
1151116001894	ADP-ribose binding site [chemical binding]; other site
1151116001895	active site
1151116001896	nudix motif; other site
1151116001897	metal binding site [ion binding]; metal-binding site
1151116001898	putative dehydrogenase; Provisional; Region: PRK11039
1151116001899	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1151116001900	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1151116001901	active site
1151116001902	metal binding site [ion binding]; metal-binding site
1151116001903	hexamer interface [polypeptide binding]; other site
1151116001904	esterase YqiA; Provisional; Region: PRK11071
1151116001905	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1151116001906	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116001907	ATP binding site [chemical binding]; other site
1151116001908	Mg2+ binding site [ion binding]; other site
1151116001909	G-X-G motif; other site
1151116001910	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1151116001911	anchoring element; other site
1151116001912	dimer interface [polypeptide binding]; other site
1151116001913	ATP binding site [chemical binding]; other site
1151116001914	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1151116001915	active site
1151116001916	metal binding site [ion binding]; metal-binding site
1151116001917	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1151116001918	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1151116001919	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1151116001920	potential frameshift: common BLAST hit: gi|322831366|ref|YP_004211393.1| DNA topoisomerase IV subunit A
1151116001921	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1151116001922	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1151116001923	putative acyl-acceptor binding pocket; other site
1151116001924	FtsI repressor; Provisional; Region: PRK10883
1151116001925	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1151116001926	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1151116001927	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116001928	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116001929	active site
1151116001930	catalytic tetrad [active]
1151116001931	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1151116001932	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1151116001933	putative NAD(P) binding site [chemical binding]; other site
1151116001934	putative substrate binding site [chemical binding]; other site
1151116001935	catalytic Zn binding site [ion binding]; other site
1151116001936	structural Zn binding site [ion binding]; other site
1151116001937	dimer interface [polypeptide binding]; other site
1151116001938	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1151116001939	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1151116001940	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116001941	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116001942	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1151116001943	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1151116001944	cystathionine beta-lyase; Provisional; Region: PRK08114
1151116001945	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1151116001946	homodimer interface [polypeptide binding]; other site
1151116001947	substrate-cofactor binding pocket; other site
1151116001948	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116001949	catalytic residue [active]
1151116001950	DctM-like transporters; Region: DctM; pfam06808
1151116001951	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1151116001952	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1151116001953	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1151116001954	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1151116001955	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1151116001956	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
1151116001957	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1151116001958	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116001959	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116001960	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116001961	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1151116001962	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1151116001963	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1151116001964	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116001965	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116001966	putative substrate translocation pore; other site
1151116001967	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1151116001968	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1151116001969	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1151116001970	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1151116001971	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
1151116001972	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase; Region: PLPDE_III_cryptic_DSD; cd06818
1151116001973	dimer interface [polypeptide binding]; other site
1151116001974	active site
1151116001975	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1151116001976	substrate binding site [chemical binding]; other site
1151116001977	catalytic residue [active]
1151116001978	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1151116001979	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1151116001980	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116001981	dimerization interface [polypeptide binding]; other site
1151116001982	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116001983	dimer interface [polypeptide binding]; other site
1151116001984	phosphorylation site [posttranslational modification]
1151116001985	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116001986	ATP binding site [chemical binding]; other site
1151116001987	Mg2+ binding site [ion binding]; other site
1151116001988	G-X-G motif; other site
1151116001989	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1151116001990	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116001991	active site
1151116001992	phosphorylation site [posttranslational modification]
1151116001993	intermolecular recognition site; other site
1151116001994	dimerization interface [polypeptide binding]; other site
1151116001995	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1151116001996	putative binding surface; other site
1151116001997	active site
1151116001998	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1151116001999	TRAM domain; Region: TRAM; pfam01938
1151116002000	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116002001	S-adenosylmethionine binding site [chemical binding]; other site
1151116002002	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1151116002003	HD domain; Region: HD_4; pfam13328
1151116002004	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1151116002005	synthetase active site [active]
1151116002006	NTP binding site [chemical binding]; other site
1151116002007	metal binding site [ion binding]; metal-binding site
1151116002008	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1151116002009	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1151116002010	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1151116002011	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1151116002012	homodimer interface [polypeptide binding]; other site
1151116002013	metal binding site [ion binding]; metal-binding site
1151116002014	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1151116002015	homodimer interface [polypeptide binding]; other site
1151116002016	active site
1151116002017	putative chemical substrate binding site [chemical binding]; other site
1151116002018	metal binding site [ion binding]; metal-binding site
1151116002019	CTP synthetase; Validated; Region: pyrG; PRK05380
1151116002020	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1151116002021	Catalytic site [active]
1151116002022	active site
1151116002023	UTP binding site [chemical binding]; other site
1151116002024	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1151116002025	active site
1151116002026	putative oxyanion hole; other site
1151116002027	catalytic triad [active]
1151116002028	enolase; Provisional; Region: eno; PRK00077
1151116002029	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1151116002030	dimer interface [polypeptide binding]; other site
1151116002031	metal binding site [ion binding]; metal-binding site
1151116002032	substrate binding pocket [chemical binding]; other site
1151116002033	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116002034	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116002035	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116002036	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116002037	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1151116002038	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1151116002039	putative active site [active]
1151116002040	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1151116002041	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116002042	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116002043	active site turn [active]
1151116002044	phosphorylation site [posttranslational modification]
1151116002045	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1151116002046	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1151116002047	putative active site cavity [active]
1151116002048	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1151116002049	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1151116002050	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1151116002051	active site
1151116002052	esterase, PHB depolymerase family; Region: esterase_phb; TIGR01840
1151116002053	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1151116002054	Flavodoxin; Region: Flavodoxin_1; pfam00258
1151116002055	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1151116002056	FAD binding pocket [chemical binding]; other site
1151116002057	FAD binding motif [chemical binding]; other site
1151116002058	catalytic residues [active]
1151116002059	NAD binding pocket [chemical binding]; other site
1151116002060	phosphate binding motif [ion binding]; other site
1151116002061	beta-alpha-beta structure motif; other site
1151116002062	sulfite reductase subunit beta; Provisional; Region: PRK13504
1151116002063	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1151116002064	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1151116002065	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1151116002066	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1151116002067	Active Sites [active]
1151116002068	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1151116002069	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1151116002070	metal binding site [ion binding]; metal-binding site
1151116002071	siroheme synthase; Provisional; Region: cysG; PRK10637
1151116002072	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1151116002073	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1151116002074	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1151116002075	active site
1151116002076	SAM binding site [chemical binding]; other site
1151116002077	homodimer interface [polypeptide binding]; other site
1151116002078	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1151116002079	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1151116002080	Active Sites [active]
1151116002081	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1151116002082	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1151116002083	CysD dimerization site [polypeptide binding]; other site
1151116002084	G1 box; other site
1151116002085	putative GEF interaction site [polypeptide binding]; other site
1151116002086	GTP/Mg2+ binding site [chemical binding]; other site
1151116002087	Switch I region; other site
1151116002088	G2 box; other site
1151116002089	G3 box; other site
1151116002090	Switch II region; other site
1151116002091	G4 box; other site
1151116002092	G5 box; other site
1151116002093	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1151116002094	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1151116002095	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1151116002096	ligand-binding site [chemical binding]; other site
1151116002097	hypothetical protein; Provisional; Region: PRK10726
1151116002098	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1151116002099	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1151116002100	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1151116002101	substrate binding site; other site
1151116002102	dimer interface; other site
1151116002103	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1151116002104	homotrimer interaction site [polypeptide binding]; other site
1151116002105	zinc binding site [ion binding]; other site
1151116002106	CDP-binding sites; other site
1151116002107	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1151116002108	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1151116002109	Permutation of conserved domain; other site
1151116002110	active site
1151116002111	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1151116002112	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1151116002113	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116002114	S-adenosylmethionine binding site [chemical binding]; other site
1151116002115	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1151116002116	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1151116002117	Peptidase family M23; Region: Peptidase_M23; pfam01551
1151116002118	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1151116002119	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1151116002120	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1151116002121	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1151116002122	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1151116002123	DNA binding residues [nucleotide binding]
1151116002124	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1151116002125	MutS domain I; Region: MutS_I; pfam01624
1151116002126	MutS domain II; Region: MutS_II; pfam05188
1151116002127	MutS domain III; Region: MutS_III; pfam05192
1151116002128	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1151116002129	Walker A/P-loop; other site
1151116002130	ATP binding site [chemical binding]; other site
1151116002131	Q-loop/lid; other site
1151116002132	ABC transporter signature motif; other site
1151116002133	Walker B; other site
1151116002134	D-loop; other site
1151116002135	H-loop/switch region; other site
1151116002136	Membrane-bound lytic murein transglycosylase B [Cell envelope biogenesis, outer membrane]; Region: MltB; COG2951
1151116002137	putative lipoprotein; Provisional; Region: PRK10533
1151116002138	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116002139	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116002140	catalytic residue [active]
1151116002141	hypothetical protein; Validated; Region: PRK03661
1151116002142	recombinase A; Provisional; Region: recA; PRK09354
1151116002143	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1151116002144	hexamer interface [polypeptide binding]; other site
1151116002145	Walker A motif; other site
1151116002146	ATP binding site [chemical binding]; other site
1151116002147	Walker B motif; other site
1151116002148	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1151116002149	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1151116002150	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1151116002151	motif 1; other site
1151116002152	active site
1151116002153	motif 2; other site
1151116002154	motif 3; other site
1151116002155	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1151116002156	DHHA1 domain; Region: DHHA1; pfam02272
1151116002157	carbon storage regulator; Provisional; Region: PRK01712
1151116002158	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1151116002159	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116002160	motif II; other site
1151116002161	Predicted membrane protein [Function unknown]; Region: COG1238
1151116002162	glutamate--cysteine ligase; Provisional; Region: PRK02107
1151116002163	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1151116002164	hypothetical protein; Provisional; Region: PRK11573
1151116002165	Domain of unknown function DUF21; Region: DUF21; pfam01595
1151116002166	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1151116002167	Transporter associated domain; Region: CorC_HlyC; smart01091
1151116002168	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1151116002169	signal recognition particle protein; Provisional; Region: PRK10867
1151116002170	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1151116002171	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1151116002172	P loop; other site
1151116002173	GTP binding site [chemical binding]; other site
1151116002174	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1151116002175	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1151116002176	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1151116002177	RimM N-terminal domain; Region: RimM; pfam01782
1151116002178	PRC-barrel domain; Region: PRC; pfam05239
1151116002179	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1151116002180	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1151116002181	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1151116002182	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
1151116002183	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1151116002184	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1151116002185	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1151116002186	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1151116002187	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1151116002188	major tail tube protein; Provisional; Region: FII; PHA02600
1151116002189	major tail sheath protein; Provisional; Region: FI; PHA02560
1151116002190	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1151116002191	Phage Tail Collar Domain; Region: Collar; pfam07484
1151116002192	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1151116002193	baseplate assembly protein; Provisional; Region: J; PHA02568
1151116002194	baseplate wedge subunit; Provisional; Region: W; PHA02516
1151116002195	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1151116002196	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1151116002197	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1151116002198	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1151116002199	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1151116002200	catalytic residues [active]
1151116002201	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; cl02059
1151116002202	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1151116002203	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1151116002204	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1151116002205	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1151116002206	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1151116002207	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1151116002208	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1151116002209	Chorismate mutase type II; Region: CM_2; cl00693
1151116002210	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1151116002211	prephenate dehydrogenase; Validated; Region: PRK08507
1151116002212	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1151116002213	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1151116002214	Prephenate dehydratase; Region: PDT; pfam00800
1151116002215	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1151116002216	putative L-Phe binding site [chemical binding]; other site
1151116002217	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1151116002218	30S subunit binding site; other site
1151116002219	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1151116002220	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1151116002221	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1151116002222	RNA binding surface [nucleotide binding]; other site
1151116002223	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1151116002224	active site
1151116002225	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650
1151116002226	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1151116002227	potential frameshift: common BLAST hit: gi|322831464|ref|YP_004211491.1| ATP-dependent chaperone ClpB
1151116002228	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1151116002229	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002230	putative substrate translocation pore; other site
1151116002231	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1151116002232	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1151116002233	domain interface [polypeptide binding]; other site
1151116002234	putative active site [active]
1151116002235	catalytic site [active]
1151116002236	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1151116002237	domain interface [polypeptide binding]; other site
1151116002238	putative active site [active]
1151116002239	catalytic site [active]
1151116002240	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1151116002241	CoA binding domain; Region: CoA_binding_2; pfam13380
1151116002242	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1151116002243	Recombinase Flp protein; Region: Flp_C; pfam05202
1151116002244	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1151116002245	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1151116002246	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1151116002247	thioredoxin 2; Provisional; Region: PRK10996
1151116002248	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1151116002249	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1151116002250	catalytic residues [active]
1151116002251	putative methyltransferase; Provisional; Region: PRK10864
1151116002252	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1151116002253	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1151116002254	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1151116002255	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002256	putative substrate translocation pore; other site
1151116002257	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002258	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1151116002259	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116002260	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116002261	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1151116002262	transcriptional repressor MprA; Provisional; Region: PRK10870
1151116002263	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1151116002264	putative L-valine exporter; Provisional; Region: PRK10408
1151116002265	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1151116002266	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1151116002267	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002268	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
1151116002269	YcfA-like protein; Region: YcfA; pfam07927
1151116002270	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1151116002271	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1151116002272	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1151116002273	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1151116002274	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1151116002275	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116002276	dimer interface [polypeptide binding]; other site
1151116002277	conserved gate region; other site
1151116002278	putative PBP binding loops; other site
1151116002279	ABC-ATPase subunit interface; other site
1151116002280	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1151116002281	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1151116002282	Walker A/P-loop; other site
1151116002283	ATP binding site [chemical binding]; other site
1151116002284	Q-loop/lid; other site
1151116002285	ABC transporter signature motif; other site
1151116002286	Walker B; other site
1151116002287	D-loop; other site
1151116002288	H-loop/switch region; other site
1151116002289	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1151116002290	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1151116002291	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116002292	active site
1151116002293	phosphorylation site [posttranslational modification]
1151116002294	intermolecular recognition site; other site
1151116002295	dimerization interface [polypeptide binding]; other site
1151116002296	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1151116002297	PAS domain; Region: PAS; smart00091
1151116002298	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116002299	ATP binding site [chemical binding]; other site
1151116002300	Mg2+ binding site [ion binding]; other site
1151116002301	G-X-G motif; other site
1151116002302	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1151116002303	NlpC/P60 family; Region: NLPC_P60; pfam00877
1151116002304	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116002305	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116002306	active site
1151116002307	catalytic tetrad [active]
1151116002308	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1151116002309	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1151116002310	dimer interface [polypeptide binding]; other site
1151116002311	putative radical transfer pathway; other site
1151116002312	diiron center [ion binding]; other site
1151116002313	tyrosyl radical; other site
1151116002314	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1151116002315	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1151116002316	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1151116002317	active site
1151116002318	dimer interface [polypeptide binding]; other site
1151116002319	catalytic residues [active]
1151116002320	effector binding site; other site
1151116002321	R2 peptide binding site; other site
1151116002322	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1151116002323	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1151116002324	catalytic residues [active]
1151116002325	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1151116002326	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1151116002327	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1151116002328	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116002329	DNA-binding site [nucleotide binding]; DNA binding site
1151116002330	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116002331	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116002332	homodimer interface [polypeptide binding]; other site
1151116002333	catalytic residue [active]
1151116002334	alpha-mannosidase; Provisional; Region: PRK09819
1151116002335	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1151116002336	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002337	major facilitator superfamily transporter; Provisional; Region: PRK05122
1151116002338	putative substrate translocation pore; other site
1151116002339	hypothetical protein; Provisional; Region: PRK10556
1151116002340	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116002341	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116002342	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116002343	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1151116002344	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1151116002345	6-phosphofructokinase 2; Provisional; Region: PRK10294
1151116002346	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1151116002347	putative substrate binding site [chemical binding]; other site
1151116002348	putative ATP binding site [chemical binding]; other site
1151116002349	Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890
1151116002350	putative active site [active]
1151116002351	putative metal binding residues [ion binding]; other site
1151116002352	signature motif; other site
1151116002353	putative triphosphate binding site [ion binding]; other site
1151116002354	dimer interface [polypeptide binding]; other site
1151116002355	putative global regulator; Reviewed; Region: PRK09559
1151116002356	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1151116002357	hypothetical protein; Provisional; Region: PRK10878
1151116002358	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1151116002359	flavodoxin FldB; Provisional; Region: PRK12359
1151116002360	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1151116002361	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1151116002362	active site
1151116002363	Int/Topo IB signature motif; other site
1151116002364	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1151116002365	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1151116002366	dimerization domain [polypeptide binding]; other site
1151116002367	dimer interface [polypeptide binding]; other site
1151116002368	catalytic residues [active]
1151116002369	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1151116002370	DHH family; Region: DHH; pfam01368
1151116002371	DHHA1 domain; Region: DHHA1; pfam02272
1151116002372	peptide chain release factor 2; Provisional; Region: PRK08787
1151116002373	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1151116002374	RF-1 domain; Region: RF-1; pfam00472
1151116002375	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1151116002376	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1151116002377	dimer interface [polypeptide binding]; other site
1151116002378	putative anticodon binding site; other site
1151116002379	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1151116002380	motif 1; other site
1151116002381	active site
1151116002382	motif 2; other site
1151116002383	motif 3; other site
1151116002384	potential protein location (hypothetical protein Q7S_03665 [Rahnella aquatilis HX2]) that overlaps RNA (tRNA-G)
1151116002385	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1151116002386	argininosuccinate synthase; Validated; Region: PRK05370
1151116002387	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116002388	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116002389	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116002390	dimerization interface [polypeptide binding]; other site
1151116002391	glutamate carboxypeptidase; Reviewed; Region: PRK06133
1151116002392	M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme; Region: M20_CPDG2; cd03885
1151116002393	metal binding site [ion binding]; metal-binding site
1151116002394	dimer interface [polypeptide binding]; other site
1151116002395	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1151116002396	Nucleoside recognition; Region: Gate; pfam07670
1151116002397	hypothetical protein; Provisional; Region: PRK10519
1151116002398	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1151116002399	M20 Peptidase Aminoacylase 1 amhX_like subfamily; Region: M20_Acy1_amhX_like; cd08018
1151116002400	metal binding site [ion binding]; metal-binding site
1151116002401	putative dimer interface [polypeptide binding]; other site
1151116002402	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1151116002403	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116002404	putative DNA binding site [nucleotide binding]; other site
1151116002405	putative Zn2+ binding site [ion binding]; other site
1151116002406	AsnC family; Region: AsnC_trans_reg; pfam01037
1151116002407	Protein of unknown function (DUF2000); Region: DUF2000; cl02074
1151116002408	putative arabinose transporter; Provisional; Region: PRK03545
1151116002409	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002410	putative substrate translocation pore; other site
1151116002411	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1151116002412	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1151116002413	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1151116002414	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1151116002415	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1151116002416	catalytic triad [active]
1151116002417	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1151116002418	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116002419	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1151116002420	Protein export membrane protein; Region: SecD_SecF; cl14618
1151116002421	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1151116002422	Protein export membrane protein; Region: SecD_SecF; cl14618
1151116002423	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1151116002424	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
1151116002425	putative active site [active]
1151116002426	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1151116002427	RelB antitoxin; Region: RelB; cl01171
1151116002428	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
1151116002429	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1151116002430	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1151116002431	Protein export membrane protein; Region: SecD_SecF; cl14618
1151116002432	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
1151116002433	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116002434	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116002435	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1151116002436	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116002437	Phosphotransferase system IIB components [Carbohydrate transport and metabolism]; Region: PtsG; COG1264
1151116002438	active site turn [active]
1151116002439	phosphorylation site [posttranslational modification]
1151116002440	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1151116002441	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116002442	DNA-binding site [nucleotide binding]; DNA binding site
1151116002443	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1151116002444	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
1151116002445	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
1151116002446	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
1151116002447	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1151116002448	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1151116002449	TPR motif; other site
1151116002450	binding surface
1151116002451	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1151116002452	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116002453	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116002454	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116002455	putative effector binding pocket; other site
1151116002456	dimerization interface [polypeptide binding]; other site
1151116002457	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1151116002458	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002459	putative substrate translocation pore; other site
1151116002460	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1151116002461	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116002462	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116002463	dimerization interface [polypeptide binding]; other site
1151116002464	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1151116002465	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1151116002466	active site
1151116002467	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1151116002468	substrate binding site [chemical binding]; other site
1151116002469	catalytic residues [active]
1151116002470	dimer interface [polypeptide binding]; other site
1151116002471	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1151116002472	methionine cluster; other site
1151116002473	active site
1151116002474	phosphorylation site [posttranslational modification]
1151116002475	metal binding site [ion binding]; metal-binding site
1151116002476	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1151116002477	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1151116002478	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1151116002479	beta-galactosidase; Region: BGL; TIGR03356
1151116002480	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1151116002481	active site
1151116002482	P-loop; other site
1151116002483	phosphorylation site [posttranslational modification]
1151116002484	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1151116002485	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116002486	DNA-binding site [nucleotide binding]; DNA binding site
1151116002487	FCD domain; Region: FCD; pfam07729
1151116002488	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116002489	Coenzyme A binding pocket [chemical binding]; other site
1151116002490	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1151116002491	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116002492	DNA binding site [nucleotide binding]
1151116002493	domain linker motif; other site
1151116002494	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1151116002495	dimerization interface (closed form) [polypeptide binding]; other site
1151116002496	ligand binding site [chemical binding]; other site
1151116002497	potential frameshift: common BLAST hit: gi|322831551|ref|YP_004211578.1| trimethylamine-N-oxide reductase (cytochrome c)
1151116002498	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1151116002499	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1151116002500	putative acyl-acceptor binding pocket; other site
1151116002501	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1151116002502	acyl-activating enzyme (AAE) consensus motif; other site
1151116002503	putative AMP binding site [chemical binding]; other site
1151116002504	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1151116002505	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002506	putative substrate translocation pore; other site
1151116002507	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116002508	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116002509	active site
1151116002510	catalytic tetrad [active]
1151116002511	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1151116002512	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1151116002513	putative DNA-binding cleft [nucleotide binding]; other site
1151116002514	putative DNA clevage site; other site
1151116002515	molecular lever; other site
1151116002516	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1151116002517	putative active site [active]
1151116002518	Ap4A binding site [chemical binding]; other site
1151116002519	nudix motif; other site
1151116002520	putative metal binding site [ion binding]; other site
1151116002521	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1151116002522	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1151116002523	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1151116002524	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1151116002525	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1151116002526	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1151116002527	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1151116002528	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1151116002529	dimerization interface [polypeptide binding]; other site
1151116002530	active site
1151116002531	hypothetical protein; Provisional; Region: PRK10506
1151116002532	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1151116002533	hypothetical protein; Provisional; Region: PRK10557
1151116002534	Protein of unknown function (DUF2509); Region: DUF2509; cl11672
1151116002535	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1151116002536	protease3; Provisional; Region: PRK15101
1151116002537	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1151116002538	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1151116002539	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1151116002540	N-acetylglutamate synthase; Validated; Region: PRK05279
1151116002541	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1151116002542	putative feedback inhibition sensing region; other site
1151116002543	putative nucleotide binding site [chemical binding]; other site
1151116002544	putative substrate binding site [chemical binding]; other site
1151116002545	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116002546	Coenzyme A binding pocket [chemical binding]; other site
1151116002547	AMIN domain; Region: AMIN; pfam11741
1151116002548	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1151116002549	active site
1151116002550	metal binding site [ion binding]; metal-binding site
1151116002551	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1151116002552	MltA specific insert domain; Region: MltA; smart00925
1151116002553	3D domain; Region: 3D; pfam06725
1151116002554	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1151116002555	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1151116002556	putative ATP binding site [chemical binding]; other site
1151116002557	putative substrate interface [chemical binding]; other site
1151116002558	cysteine desulfurase, sulfur acceptor subunit CsdE; Region: FeS_syn_CsdE; TIGR03391
1151116002559	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1151116002560	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1151116002561	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116002562	catalytic residue [active]
1151116002563	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1151116002564	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1151116002565	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116002566	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1151116002567	dimerization interface [polypeptide binding]; other site
1151116002568	substrate binding pocket [chemical binding]; other site
1151116002569	hypothetical protein; Provisional; Region: PRK10873
1151116002570	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1151116002571	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1151116002572	flap endonuclease-like protein; Provisional; Region: PRK09482
1151116002573	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1151116002574	active site
1151116002575	metal binding site 1 [ion binding]; metal-binding site
1151116002576	putative 5' ssDNA interaction site; other site
1151116002577	metal binding site 3; metal-binding site
1151116002578	metal binding site 2 [ion binding]; metal-binding site
1151116002579	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1151116002580	putative DNA binding site [nucleotide binding]; other site
1151116002581	putative metal binding site [ion binding]; other site
1151116002582	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1151116002583	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1151116002584	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1151116002585	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1151116002586	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1151116002587	SecY interacting protein Syd; Provisional; Region: PRK04968
1151116002588	benzoate transport; Region: 2A0115; TIGR00895
1151116002589	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002590	putative substrate translocation pore; other site
1151116002591	tRNA pseudouridine synthase C; Region: DUF446; pfam04287
1151116002592	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1151116002593	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1151116002594	probable active site [active]
1151116002595	flavodoxin; Provisional; Region: PRK08105
1151116002596	hypothetical protein; Provisional; Region: PRK13677
1151116002597	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1151116002598	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1151116002599	trimer interface [polypeptide binding]; other site
1151116002600	active site
1151116002601	substrate binding site [chemical binding]; other site
1151116002602	CoA binding site [chemical binding]; other site
1151116002603	PII uridylyl-transferase; Provisional; Region: PRK05007
1151116002604	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1151116002605	metal binding triad; other site
1151116002606	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1151116002607	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1151116002608	Zn2+ binding site [ion binding]; other site
1151116002609	Mg2+ binding site [ion binding]; other site
1151116002610	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1151116002611	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1151116002612	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1151116002613	active site
1151116002614	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1151116002615	rRNA interaction site [nucleotide binding]; other site
1151116002616	S8 interaction site; other site
1151116002617	putative laminin-1 binding site; other site
1151116002618	elongation factor Ts; Provisional; Region: tsf; PRK09377
1151116002619	UBA/TS-N domain; Region: UBA; pfam00627
1151116002620	Elongation factor TS; Region: EF_TS; pfam00889
1151116002621	Elongation factor TS; Region: EF_TS; pfam00889
1151116002622	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1151116002623	putative nucleotide binding site [chemical binding]; other site
1151116002624	uridine monophosphate binding site [chemical binding]; other site
1151116002625	homohexameric interface [polypeptide binding]; other site
1151116002626	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1151116002627	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1151116002628	hinge region; other site
1151116002629	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1151116002630	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1151116002631	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1151116002632	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1151116002633	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1151116002634	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1151116002635	catalytic residue [active]
1151116002636	putative FPP diphosphate  binding site; other site
1151116002637	putative FPP binding hydrophobic cleft; other site
1151116002638	dimer interface [polypeptide binding]; other site
1151116002639	putative IPP diphosphate binding site; other site
1151116002640	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1151116002641	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1151116002642	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1151116002643	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1151116002644	active site
1151116002645	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1151116002646	protein binding site [polypeptide binding]; other site
1151116002647	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1151116002648	protein binding site [polypeptide binding]; other site
1151116002649	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1151116002650	putative substrate binding region [chemical binding]; other site
1151116002651	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1151116002652	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116002653	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116002654	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116002655	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116002656	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116002657	Surface antigen; Region: Bac_surface_Ag; pfam01103
1151116002658	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: HlpA; COG2825
1151116002659	periplasmic chaperone; Provisional; Region: PRK10780
1151116002660	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1151116002661	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1151116002662	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1151116002663	trimer interface [polypeptide binding]; other site
1151116002664	active site
1151116002665	UDP-GlcNAc binding site [chemical binding]; other site
1151116002666	lipid binding site [chemical binding]; lipid-binding site
1151116002667	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1151116002668	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1151116002669	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1151116002670	active site
1151116002671	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1151116002672	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1151116002673	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1151116002674	RNA/DNA hybrid binding site [nucleotide binding]; other site
1151116002675	active site
1151116002676	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1151116002677	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1151116002678	putative active site [active]
1151116002679	putative PHP Thumb interface [polypeptide binding]; other site
1151116002680	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1151116002681	generic binding surface II; other site
1151116002682	generic binding surface I; other site
1151116002683	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1151116002684	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1151116002685	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1151116002686	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1151116002687	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1151116002688	homodimer interface [polypeptide binding]; other site
1151116002689	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116002690	catalytic residue [active]
1151116002691	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1151116002692	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1151116002693	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1151116002694	putative metal binding site [ion binding]; other site
1151116002695	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1151116002696	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1151116002697	Ligand Binding Site [chemical binding]; other site
1151116002698	TilS substrate binding domain; Region: TilS; pfam09179
1151116002699	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1151116002700	Cytochrome c553 [Energy production and conversion]; Region: COG2863
1151116002701	Rho-binding antiterminator; Provisional; Region: PRK11625
1151116002702	hypothetical protein; Provisional; Region: PRK04964
1151116002703	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1151116002704	hypothetical protein; Provisional; Region: PRK09256
1151116002705	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1151116002706	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1151116002707	NlpE N-terminal domain; Region: NlpE; pfam04170
1151116002708	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1151116002709	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1151116002710	dimer interface [polypeptide binding]; other site
1151116002711	motif 1; other site
1151116002712	active site
1151116002713	motif 2; other site
1151116002714	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1151116002715	putative deacylase active site [active]
1151116002716	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1151116002717	active site
1151116002718	motif 3; other site
1151116002719	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1151116002720	anticodon binding site; other site
1151116002721	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1151116002722	homodimer interaction site [polypeptide binding]; other site
1151116002723	cofactor binding site; other site
1151116002724	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1151116002725	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1151116002726	lipoprotein, YaeC family; Region: TIGR00363
1151116002727	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116002728	dimer interface [polypeptide binding]; other site
1151116002729	conserved gate region; other site
1151116002730	ABC-ATPase subunit interface; other site
1151116002731	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1151116002732	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1151116002733	Walker A/P-loop; other site
1151116002734	ATP binding site [chemical binding]; other site
1151116002735	Q-loop/lid; other site
1151116002736	ABC transporter signature motif; other site
1151116002737	Walker B; other site
1151116002738	D-loop; other site
1151116002739	H-loop/switch region; other site
1151116002740	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1151116002741	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
1151116002742	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116002743	active site
1151116002744	motif I; other site
1151116002745	motif II; other site
1151116002746	Beta-ketoacyl synthase, N-terminal domain; Region: Ketoacyl-synt_2; pfam13723
1151116002747	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1151116002748	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1151116002749	putative acyl-acceptor binding pocket; other site
1151116002750	Phosphopantetheine attachment site; Region: PP-binding; cl09936
1151116002751	acyl carrier protein; Provisional; Region: PRK05350
1151116002752	Predicted membrane protein [Function unknown]; Region: COG4648
1151116002753	AMP-binding enzyme; Region: AMP-binding; pfam00501
1151116002754	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1151116002755	acyl-activating enzyme (AAE) consensus motif; other site
1151116002756	AMP binding site [chemical binding]; other site
1151116002757	active site
1151116002758	CoA binding site [chemical binding]; other site
1151116002759	FabA/Z, beta-hydroxyacyl-acyl carrier protein (ACP)-dehydratases: One of several distinct enzyme types of the dissociative, type II, fatty acid synthase system (found in bacteria and plants) required to complete successive cycles of fatty acid elongation; Region: FabA_FabZ; cd00493
1151116002760	active site 2 [active]
1151116002761	dimer interface [polypeptide binding]; other site
1151116002762	active site 1 [active]
1151116002763	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1151116002764	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1151116002765	Ligand binding site; other site
1151116002766	Putative Catalytic site; other site
1151116002767	DXD motif; other site
1151116002768	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1151116002769	putative acyl-acceptor binding pocket; other site
1151116002770	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1151116002771	active site
1151116002772	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1151116002773	Predicted exporter [General function prediction only]; Region: COG4258
1151116002774	Protein of unknown function (DUF3261); Region: DUF3261; pfam11659
1151116002775	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK09185
1151116002776	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1151116002777	dimer interface [polypeptide binding]; other site
1151116002778	active site
1151116002779	Domain of unknown function, appears to be related to a diverse group of beta-hydroxydecanoyl ACP dehydratases (FabA) and beta-hydroxyacyl ACP dehydratases (FabZ). This group appears to lack the conserved active site histidine of FabA and FabZ; Region: FabA_like; cd01289
1151116002780	putative active site 1 [active]
1151116002781	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116002782	3-oxoacyl-(acyl-carrier-protein) reductase, putative; Region: fabG_rel; TIGR01831
1151116002783	NAD(P) binding site [chemical binding]; other site
1151116002784	active site
1151116002785	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK09116
1151116002786	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1151116002787	dimer interface [polypeptide binding]; other site
1151116002788	active site
1151116002789	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1151116002790	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1151116002791	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116002792	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116002793	active site
1151116002794	catalytic tetrad [active]
1151116002795	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116002796	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116002797	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116002798	dimerization interface [polypeptide binding]; other site
1151116002799	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1151116002800	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116002801	putative substrate translocation pore; other site
1151116002802	hypothetical protein; Provisional; Region: PRK05421
1151116002803	putative catalytic site [active]
1151116002804	putative metal binding site [ion binding]; other site
1151116002805	putative phosphate binding site [ion binding]; other site
1151116002806	putative catalytic site [active]
1151116002807	putative phosphate binding site [ion binding]; other site
1151116002808	putative metal binding site [ion binding]; other site
1151116002809	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1151116002810	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116002811	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116002812	catalytic residue [active]
1151116002813	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1151116002814	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1151116002815	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1151116002816	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1151116002817	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
1151116002818	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116002819	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1151116002820	RNA/DNA hybrid binding site [nucleotide binding]; other site
1151116002821	active site
1151116002822	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
1151116002823	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
1151116002824	putative active site; other site
1151116002825	catalytic triad [active]
1151116002826	putative dimer interface [polypeptide binding]; other site
1151116002827	agmatine deiminase; Provisional; Region: PRK13551
1151116002828	agmatine deiminase; Region: agmatine_aguA; TIGR03380
1151116002829	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1151116002830	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1151116002831	active site
1151116002832	catalytic site [active]
1151116002833	substrate binding site [chemical binding]; other site
1151116002834	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555
1151116002835	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1151116002836	Na binding site [ion binding]; other site
1151116002837	putative substrate binding site [chemical binding]; other site
1151116002838	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116002839	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116002840	DNA-binding site [nucleotide binding]; DNA binding site
1151116002841	FCD domain; Region: FCD; pfam07729
1151116002842	Hydantoin racemase [Amino acid transport and metabolism]; Region: COG4126
1151116002843	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
1151116002844	Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977
1151116002845	active site
1151116002846	catalytic site [active]
1151116002847	tetramer interface [polypeptide binding]; other site
1151116002848	Protein of unknown function (DUF3225); Region: DUF3225; pfam11533
1151116002849	SnoaL-like domain; Region: SnoaL_3; pfam13474
1151116002850	amidase; Provisional; Region: PRK09201
1151116002851	Amidase; Region: Amidase; cl11426
1151116002852	Protein of unknown function (DUF4089); Region: DUF4089; pfam13318
1151116002853	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1151116002854	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1151116002855	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1151116002856	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116002857	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1151116002858	putative active site [active]
1151116002859	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116002860	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116002861	substrate binding pocket [chemical binding]; other site
1151116002862	membrane-bound complex binding site; other site
1151116002863	hinge residues; other site
1151116002864	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116002865	dimer interface [polypeptide binding]; other site
1151116002866	conserved gate region; other site
1151116002867	putative PBP binding loops; other site
1151116002868	ABC-ATPase subunit interface; other site
1151116002869	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116002870	ABC-ATPase subunit interface; other site
1151116002871	putative PBP binding loops; other site
1151116002872	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116002873	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116002874	Walker A/P-loop; other site
1151116002875	ATP binding site [chemical binding]; other site
1151116002876	Q-loop/lid; other site
1151116002877	ABC transporter signature motif; other site
1151116002878	Walker B; other site
1151116002879	D-loop; other site
1151116002880	H-loop/switch region; other site
1151116002881	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1151116002882	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116002883	catalytic residue [active]
1151116002884	allantoate amidohydrolase; Reviewed; Region: PRK09290
1151116002885	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1151116002886	active site
1151116002887	metal binding site [ion binding]; metal-binding site
1151116002888	dimer interface [polypeptide binding]; other site
1151116002889	OHCU decarboxylase; Region: UraD_2; TIGR03180
1151116002890	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1151116002891	active site
1151116002892	homotetramer interface [polypeptide binding]; other site
1151116002893	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1151116002894	conserved cys residue [active]
1151116002895	Domain of unknown function (DUF1993); Region: DUF1993; pfam09351
1151116002896	C-N hydrolase family amidase; Provisional; Region: PRK10438
1151116002897	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1151116002898	putative active site [active]
1151116002899	catalytic triad [active]
1151116002900	dimer interface [polypeptide binding]; other site
1151116002901	multimer interface [polypeptide binding]; other site
1151116002902	methionine aminotransferase; Validated; Region: PRK09082
1151116002903	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116002904	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116002905	homodimer interface [polypeptide binding]; other site
1151116002906	catalytic residue [active]
1151116002907	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
1151116002908	intersubunit interface [polypeptide binding]; other site
1151116002909	active site
1151116002910	Zn2+ binding site [ion binding]; other site
1151116002911	2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Region: enolase-ppase; TIGR01691
1151116002912	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
1151116002913	Cupin domain; Region: Cupin_2; cl17218
1151116002914	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
1151116002915	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1151116002916	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
1151116002917	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1151116002918	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1151116002919	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1151116002920	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1151116002921	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1151116002922	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1151116002923	active site
1151116002924	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1151116002925	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1151116002926	dimer interface [polypeptide binding]; other site
1151116002927	active site
1151116002928	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1151116002929	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1151116002930	putative active site [active]
1151116002931	putative dimer interface [polypeptide binding]; other site
1151116002932	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1151116002933	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1151116002934	active site
1151116002935	DNA polymerase IV; Validated; Region: PRK02406
1151116002936	DNA binding site [nucleotide binding]
1151116002937	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1151116002938	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1151116002939	metal binding site [ion binding]; metal-binding site
1151116002940	dimer interface [polypeptide binding]; other site
1151116002941	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1151116002942	active site
1151116002943	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1151116002944	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1151116002945	gamma-glutamyl kinase; Provisional; Region: PRK05429
1151116002946	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1151116002947	nucleotide binding site [chemical binding]; other site
1151116002948	homotetrameric interface [polypeptide binding]; other site
1151116002949	putative phosphate binding site [ion binding]; other site
1151116002950	putative allosteric binding site; other site
1151116002951	PUA domain; Region: PUA; pfam01472
1151116002952	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1151116002953	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1151116002954	putative catalytic cysteine [active]
1151116002955	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116002956	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116002957	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116002958	dimerization interface [polypeptide binding]; other site
1151116002959	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1151116002960	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1151116002961	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1151116002962	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1151116002963	Bacterial self-protective colicin-like immunity; Region: Colicin_immun; pfam09204
1151116002964	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
1151116002965	PAAR motif; Region: PAAR_motif; pfam05488
1151116002966	S-type Pyocin; Region: Pyocin_S; pfam06958
1151116002967	Cytotoxic; Region: Cytotoxic; pfam09000
1151116002968	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
1151116002969	S-type Pyocin; Region: Pyocin_S; pfam06958
1151116002970	NIPSNAP; Region: NIPSNAP; pfam07978
1151116002971	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116002972	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116002973	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1151116002974	putative effector binding pocket; other site
1151116002975	putative dimerization interface [polypeptide binding]; other site
1151116002976	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116002977	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116002978	active site
1151116002979	catalytic tetrad [active]
1151116002980	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116002981	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116002982	active site
1151116002983	catalytic tetrad [active]
1151116002984	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116002985	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1151116002986	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1151116002987	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1151116002988	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
1151116002989	metal binding site [ion binding]; metal-binding site
1151116002990	putative dimer interface [polypeptide binding]; other site
1151116002991	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1151116002992	active site
1151116002993	substrate binding site [chemical binding]; other site
1151116002994	trimer interface [polypeptide binding]; other site
1151116002995	CoA binding site [chemical binding]; other site
1151116002996	Cache domain; Region: Cache_1; pfam02743
1151116002997	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116002998	dimerization interface [polypeptide binding]; other site
1151116002999	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1151116003000	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116003001	dimer interface [polypeptide binding]; other site
1151116003002	putative CheW interface [polypeptide binding]; other site
1151116003003	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1151116003004	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1151116003005	Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Region: PBP1_allose_binding; cd06320
1151116003006	ligand binding site [chemical binding]; other site
1151116003007	dimerization interface [polypeptide binding]; other site
1151116003008	zinc binding site [ion binding]; other site
1151116003009	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1151116003010	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116003011	Walker A/P-loop; other site
1151116003012	ATP binding site [chemical binding]; other site
1151116003013	Q-loop/lid; other site
1151116003014	ABC transporter signature motif; other site
1151116003015	Walker B; other site
1151116003016	D-loop; other site
1151116003017	H-loop/switch region; other site
1151116003018	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116003019	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116003020	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116003021	TM-ABC transporter signature motif; other site
1151116003022	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
1151116003023	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116003024	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1151116003025	putative active site [active]
1151116003026	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116003027	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1151116003028	substrate binding site [chemical binding]; other site
1151116003029	dimer interface [polypeptide binding]; other site
1151116003030	ATP binding site [chemical binding]; other site
1151116003031	Rdx family; Region: Rdx; cl01407
1151116003032	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1151116003033	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1151116003034	active site
1151116003035	FMN binding site [chemical binding]; other site
1151116003036	substrate binding site [chemical binding]; other site
1151116003037	homotetramer interface [polypeptide binding]; other site
1151116003038	catalytic residue [active]
1151116003039	potential frameshift: common BLAST hit: gi|322831717|ref|YP_004211744.1| exodeoxyribonuclease V subunit gamma
1151116003040	potential frameshift: common BLAST hit: gi|322831718|ref|YP_004211745.1| exodeoxyribonuclease V subunit beta
1151116003041	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1151116003042	AAA domain; Region: AAA_30; pfam13604
1151116003043	Family description; Region: UvrD_C_2; pfam13538
1151116003044	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1151116003045	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116003046	putative substrate translocation pore; other site
1151116003047	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1151116003048	Beta-lactamase; Region: Beta-lactamase; pfam00144
1151116003049	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116003050	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116003051	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_7; cd08476
1151116003052	putative effector binding pocket; other site
1151116003053	putative dimerization interface [polypeptide binding]; other site
1151116003054	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1151116003055	Coenzyme A binding pocket [chemical binding]; other site
1151116003056	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116003057	non-specific DNA binding site [nucleotide binding]; other site
1151116003058	salt bridge; other site
1151116003059	sequence-specific DNA binding site [nucleotide binding]; other site
1151116003060	2TM domain; Region: 2TM; pfam13239
1151116003061	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1151116003062	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116003063	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116003064	metal binding site [ion binding]; metal-binding site
1151116003065	active site
1151116003066	I-site; other site
1151116003067	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1151116003068	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1151116003069	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1151116003070	DNA-binding site [nucleotide binding]; DNA binding site
1151116003071	RNA-binding motif; other site
1151116003072	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116003073	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116003074	putative substrate translocation pore; other site
1151116003075	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1151116003076	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1151116003077	active site
1151116003078	tetramer interface [polypeptide binding]; other site
1151116003079	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1151116003080	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116003081	putative substrate translocation pore; other site
1151116003082	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1151116003083	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1151116003084	catalytic site [active]
1151116003085	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116003086	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116003087	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116003088	penicillin-binding protein 2; Provisional; Region: PRK10795
1151116003089	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1151116003090	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1151116003091	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1151116003092	HAMP domain; Region: HAMP; pfam00672
1151116003093	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116003094	dimer interface [polypeptide binding]; other site
1151116003095	phosphorylation site [posttranslational modification]
1151116003096	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116003097	ATP binding site [chemical binding]; other site
1151116003098	Mg2+ binding site [ion binding]; other site
1151116003099	G-X-G motif; other site
1151116003100	hypothetical protein; Provisional; Region: PRK10722
1151116003101	response regulator GlrR; Provisional; Region: PRK15115
1151116003102	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116003103	active site
1151116003104	phosphorylation site [posttranslational modification]
1151116003105	intermolecular recognition site; other site
1151116003106	dimerization interface [polypeptide binding]; other site
1151116003107	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116003108	Walker A motif; other site
1151116003109	ATP binding site [chemical binding]; other site
1151116003110	Walker B motif; other site
1151116003111	arginine finger; other site
1151116003112	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1151116003113	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1151116003114	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
1151116003115	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1151116003116	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1151116003117	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1151116003118	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1151116003119	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1151116003120	Cytochrome c; Region: Cytochrom_C; pfam00034
1151116003121	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1151116003122	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1151116003123	heme-binding site [chemical binding]; other site
1151116003124	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1151116003125	FAD binding pocket [chemical binding]; other site
1151116003126	FAD binding motif [chemical binding]; other site
1151116003127	phosphate binding motif [ion binding]; other site
1151116003128	beta-alpha-beta structure motif; other site
1151116003129	NAD binding pocket [chemical binding]; other site
1151116003130	Heme binding  pocket [chemical binding]; other site
1151116003131	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1151116003132	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1151116003133	dimer interface [polypeptide binding]; other site
1151116003134	active site
1151116003135	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1151116003136	folate binding site [chemical binding]; other site
1151116003137	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1151116003138	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116003139	putative substrate translocation pore; other site
1151116003140	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1151116003141	PRD domain; Region: PRD; pfam00874
1151116003142	Protein of unknown function (DUF1007); Region: DUF1007; pfam06226
1151116003143	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1151116003144	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1151116003145	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1151116003146	active site
1151116003147	dimerization interface [polypeptide binding]; other site
1151116003148	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1151116003149	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1151116003150	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1151116003151	Rrf2 family protein; Region: rrf2_super; TIGR00738
1151116003152	cysteine desulfurase; Provisional; Region: PRK14012
1151116003153	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1151116003154	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116003155	catalytic residue [active]
1151116003156	aminopeptidase B; Provisional; Region: PRK05015
1151116003157	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1151116003158	interface (dimer of trimers) [polypeptide binding]; other site
1151116003159	Substrate-binding/catalytic site; other site
1151116003160	Zn-binding sites [ion binding]; other site
1151116003161	SseB protein; Region: SseB; pfam07179
1151116003162	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1151116003163	active site
1151116003164	multimer interface [polypeptide binding]; other site
1151116003165	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1151116003166	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116003167	FeS/SAM binding site; other site
1151116003168	Tfp pilus assembly protein PilF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilF; COG3063
1151116003169	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1151116003170	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1151116003171	binding surface
1151116003172	TPR motif; other site
1151116003173	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1151116003174	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116003175	non-specific DNA binding site [nucleotide binding]; other site
1151116003176	salt bridge; other site
1151116003177	sequence-specific DNA binding site [nucleotide binding]; other site
1151116003178	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1151116003179	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1151116003180	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1151116003181	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1151116003182	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1151116003183	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1151116003184	dimer interface [polypeptide binding]; other site
1151116003185	motif 1; other site
1151116003186	active site
1151116003187	motif 2; other site
1151116003188	motif 3; other site
1151116003189	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1151116003190	anticodon binding site; other site
1151116003191	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1151116003192	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1151116003193	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1151116003194	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1151116003195	Trp docking motif [polypeptide binding]; other site
1151116003196	GTP-binding protein Der; Reviewed; Region: PRK00093
1151116003197	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1151116003198	G1 box; other site
1151116003199	GTP/Mg2+ binding site [chemical binding]; other site
1151116003200	Switch I region; other site
1151116003201	G2 box; other site
1151116003202	Switch II region; other site
1151116003203	G3 box; other site
1151116003204	G4 box; other site
1151116003205	G5 box; other site
1151116003206	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1151116003207	G1 box; other site
1151116003208	GTP/Mg2+ binding site [chemical binding]; other site
1151116003209	Switch I region; other site
1151116003210	G2 box; other site
1151116003211	G3 box; other site
1151116003212	Switch II region; other site
1151116003213	G4 box; other site
1151116003214	G5 box; other site
1151116003215	Predicted permeases [General function prediction only]; Region: COG0679
1151116003216	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1151116003217	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1151116003218	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1151116003219	active site
1151116003220	Zn binding site [ion binding]; other site
1151116003221	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116003222	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116003223	DNA binding site [nucleotide binding]
1151116003224	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1151116003225	ligand binding site [chemical binding]; other site
1151116003226	dimerization interface [polypeptide binding]; other site
1151116003227	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116003228	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116003229	putative substrate translocation pore; other site
1151116003230	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1151116003231	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1151116003232	Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599
1151116003233	putative active site [active]
1151116003234	putative catalytic site [active]
1151116003235	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1151116003236	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1151116003237	generic binding surface II; other site
1151116003238	generic binding surface I; other site
1151116003239	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1151116003240	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1151116003241	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1151116003242	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1151116003243	active site
1151116003244	GMP synthase; Reviewed; Region: guaA; PRK00074
1151116003245	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1151116003246	AMP/PPi binding site [chemical binding]; other site
1151116003247	candidate oxyanion hole; other site
1151116003248	catalytic triad [active]
1151116003249	potential glutamine specificity residues [chemical binding]; other site
1151116003250	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1151116003251	ATP Binding subdomain [chemical binding]; other site
1151116003252	Ligand Binding sites [chemical binding]; other site
1151116003253	Dimerization subdomain; other site
1151116003254	PAS domain S-box; Region: sensory_box; TIGR00229
1151116003255	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116003256	putative active site [active]
1151116003257	heme pocket [chemical binding]; other site
1151116003258	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1151116003259	GAF domain; Region: GAF; pfam01590
1151116003260	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116003261	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116003262	metal binding site [ion binding]; metal-binding site
1151116003263	active site
1151116003264	I-site; other site
1151116003265	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1151116003266	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1151116003267	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116003268	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116003269	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116003270	dimerization interface [polypeptide binding]; other site
1151116003271	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1151116003272	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1151116003273	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116003274	Coenzyme A binding pocket [chemical binding]; other site
1151116003275	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1151116003276	substrate binding site [chemical binding]; other site
1151116003277	multimerization interface [polypeptide binding]; other site
1151116003278	ATP binding site [chemical binding]; other site
1151116003279	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1151116003280	dimer interface [polypeptide binding]; other site
1151116003281	substrate binding site [chemical binding]; other site
1151116003282	ATP binding site [chemical binding]; other site
1151116003283	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1151116003284	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116003285	DNA-binding site [nucleotide binding]; DNA binding site
1151116003286	FCD domain; Region: FCD; pfam07729
1151116003287	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1151116003288	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1151116003289	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116003290	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1151116003291	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1151116003292	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1151116003293	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1151116003294	chorismate mutase; Provisional; Region: PRK08055
1151116003295	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116003296	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116003297	putative substrate translocation pore; other site
1151116003298	putative oxidoreductase; Provisional; Region: PRK10083
1151116003299	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1151116003300	putative NAD(P) binding site [chemical binding]; other site
1151116003301	catalytic Zn binding site [ion binding]; other site
1151116003302	structural Zn binding site [ion binding]; other site
1151116003303	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1151116003304	metal binding site [ion binding]; metal-binding site
1151116003305	substrate binding pocket [chemical binding]; other site
1151116003306	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1151116003307	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
1151116003308	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1151116003309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116003310	putative substrate translocation pore; other site
1151116003311	lipid kinase; Reviewed; Region: PRK13054
1151116003312	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1151116003313	putative protease; Provisional; Region: PRK15452
1151116003314	Peptidase family U32; Region: Peptidase_U32; pfam01136
1151116003315	Uncharacterized conserved protein [Function unknown]; Region: COG3422
1151116003316	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
1151116003317	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1151116003318	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116003319	active site
1151116003320	phosphorylation site [posttranslational modification]
1151116003321	intermolecular recognition site; other site
1151116003322	dimerization interface [polypeptide binding]; other site
1151116003323	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116003324	DNA binding site [nucleotide binding]
1151116003325	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1151116003326	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116003327	dimerization interface [polypeptide binding]; other site
1151116003328	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116003329	dimer interface [polypeptide binding]; other site
1151116003330	phosphorylation site [posttranslational modification]
1151116003331	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116003332	ATP binding site [chemical binding]; other site
1151116003333	Mg2+ binding site [ion binding]; other site
1151116003334	G-X-G motif; other site
1151116003335	putative transporter; Provisional; Region: PRK10504
1151116003336	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116003337	putative substrate translocation pore; other site
1151116003338	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116003339	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116003340	active site
1151116003341	catalytic tetrad [active]
1151116003342	putative chaperone; Provisional; Region: PRK11678
1151116003343	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1151116003344	nucleotide binding site [chemical binding]; other site
1151116003345	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1151116003346	SBD interface [polypeptide binding]; other site
1151116003347	transketolase; Reviewed; Region: PRK12753
1151116003348	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1151116003349	TPP-binding site [chemical binding]; other site
1151116003350	dimer interface [polypeptide binding]; other site
1151116003351	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1151116003352	PYR/PP interface [polypeptide binding]; other site
1151116003353	dimer interface [polypeptide binding]; other site
1151116003354	TPP binding site [chemical binding]; other site
1151116003355	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1151116003356	transaldolase-like protein; Provisional; Region: PTZ00411
1151116003357	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1151116003358	active site
1151116003359	dimer interface [polypeptide binding]; other site
1151116003360	catalytic residue [active]
1151116003361	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1151116003362	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1151116003363	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1151116003364	putative NAD(P) binding site [chemical binding]; other site
1151116003365	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1151116003366	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1151116003367	active site
1151116003368	tetramer interface [polypeptide binding]; other site
1151116003369	hypothetical protein; Validated; Region: PRK00124
1151116003370	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1151116003371	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1151116003372	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1151116003373	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1151116003374	active site
1151116003375	metal binding site [ion binding]; metal-binding site
1151116003376	putative acetyltransferase; Provisional; Region: PRK03624
1151116003377	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116003378	Coenzyme A binding pocket [chemical binding]; other site
1151116003379	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1151116003380	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1151116003381	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1151116003382	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1151116003383	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1151116003384	thiosulfate transporter subunit; Provisional; Region: PRK10852
1151116003385	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1151116003386	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1151116003387	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116003388	dimer interface [polypeptide binding]; other site
1151116003389	conserved gate region; other site
1151116003390	putative PBP binding loops; other site
1151116003391	ABC-ATPase subunit interface; other site
1151116003392	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1151116003393	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116003394	dimer interface [polypeptide binding]; other site
1151116003395	conserved gate region; other site
1151116003396	putative PBP binding loops; other site
1151116003397	ABC-ATPase subunit interface; other site
1151116003398	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1151116003399	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1151116003400	Walker A/P-loop; other site
1151116003401	ATP binding site [chemical binding]; other site
1151116003402	Q-loop/lid; other site
1151116003403	ABC transporter signature motif; other site
1151116003404	Walker B; other site
1151116003405	D-loop; other site
1151116003406	H-loop/switch region; other site
1151116003407	TOBE-like domain; Region: TOBE_3; pfam12857
1151116003408	cysteine synthase B; Region: cysM; TIGR01138
1151116003409	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1151116003410	dimer interface [polypeptide binding]; other site
1151116003411	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116003412	catalytic residue [active]
1151116003413	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1151116003414	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116003415	active site
1151116003416	phosphorylation site [posttranslational modification]
1151116003417	intermolecular recognition site; other site
1151116003418	dimerization interface [polypeptide binding]; other site
1151116003419	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116003420	DNA binding site [nucleotide binding]
1151116003421	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116003422	dimerization interface [polypeptide binding]; other site
1151116003423	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116003424	dimer interface [polypeptide binding]; other site
1151116003425	phosphorylation site [posttranslational modification]
1151116003426	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116003427	ATP binding site [chemical binding]; other site
1151116003428	Mg2+ binding site [ion binding]; other site
1151116003429	G-X-G motif; other site
1151116003430	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1151116003431	HPr interaction site; other site
1151116003432	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1151116003433	active site
1151116003434	phosphorylation site [posttranslational modification]
1151116003435	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1151116003436	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1151116003437	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1151116003438	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1151116003439	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1151116003440	dimerization domain swap beta strand [polypeptide binding]; other site
1151116003441	regulatory protein interface [polypeptide binding]; other site
1151116003442	active site
1151116003443	regulatory phosphorylation site [posttranslational modification]; other site
1151116003444	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1151116003445	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1151116003446	dimer interface [polypeptide binding]; other site
1151116003447	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116003448	catalytic residue [active]
1151116003449	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1151116003450	cell division protein ZipA; Provisional; Region: PRK03427
1151116003451	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1151116003452	FtsZ protein binding site [polypeptide binding]; other site
1151116003453	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1151116003454	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1151116003455	nucleotide binding pocket [chemical binding]; other site
1151116003456	K-X-D-G motif; other site
1151116003457	catalytic site [active]
1151116003458	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1151116003459	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1151116003460	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
1151116003461	DNA binding site [nucleotide binding]
1151116003462	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1151116003463	Dimer interface [polypeptide binding]; other site
1151116003464	BRCT sequence motif; other site
1151116003465	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
1151116003466	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1151116003467	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1151116003468	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116003469	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116003470	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1151116003471	putative dimerization interface [polypeptide binding]; other site
1151116003472	Bacterial protein of unknown function (DUF925); Region: DUF925; pfam06042
1151116003473	ethanolamine permease; Region: 2A0305; TIGR00908
1151116003474	ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067
1151116003475	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1151116003476	ethanolamine ammonia-lyase small subunit; Provisional; Region: PRK05465
1151116003477	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1151116003478	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1151116003479	active site
1151116003480	HIGH motif; other site
1151116003481	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1151116003482	active site
1151116003483	KMSKS motif; other site
1151116003484	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1151116003485	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116003486	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116003487	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116003488	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1151116003489	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1151116003490	Nucleoside recognition; Region: Gate; pfam07670
1151116003491	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1151116003492	manganese transport protein MntH; Reviewed; Region: PRK00701
1151116003493	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1151116003494	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1151116003495	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116003496	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116003497	active site
1151116003498	catalytic tetrad [active]
1151116003499	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
1151116003500	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1151116003501	dimer interface [polypeptide binding]; other site
1151116003502	PYR/PP interface [polypeptide binding]; other site
1151116003503	TPP binding site [chemical binding]; other site
1151116003504	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1151116003505	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1151116003506	TPP-binding site [chemical binding]; other site
1151116003507	dimer interface [polypeptide binding]; other site
1151116003508	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116003509	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116003510	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116003511	dimerization interface [polypeptide binding]; other site
1151116003512	Predicted membrane protein [Function unknown]; Region: COG4125
1151116003513	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1151116003514	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1151116003515	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1151116003516	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1151116003517	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1151116003518	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1151116003519	Cl- selectivity filter; other site
1151116003520	Cl- binding residues [ion binding]; other site
1151116003521	pore gating glutamate residue; other site
1151116003522	dimer interface [polypeptide binding]; other site
1151116003523	glucokinase, proteobacterial type; Region: glk; TIGR00749
1151116003524	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116003525	nucleotide binding site [chemical binding]; other site
1151116003526	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1151116003527	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116003528	active site
1151116003529	phosphorylation site [posttranslational modification]
1151116003530	intermolecular recognition site; other site
1151116003531	dimerization interface [polypeptide binding]; other site
1151116003532	LytTr DNA-binding domain; Region: LytTR; pfam04397
1151116003533	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1151116003534	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1151116003535	Histidine kinase; Region: His_kinase; pfam06580
1151116003536	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116003537	ATP binding site [chemical binding]; other site
1151116003538	Mg2+ binding site [ion binding]; other site
1151116003539	G-X-G motif; other site
1151116003540	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1151116003541	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1151116003542	Coenzyme A binding pocket [chemical binding]; other site
1151116003543	aminotransferase; Validated; Region: PRK08175
1151116003544	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116003545	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116003546	homodimer interface [polypeptide binding]; other site
1151116003547	catalytic residue [active]
1151116003548	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116003549	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116003550	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1151116003551	substrate binding site [chemical binding]; other site
1151116003552	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1151116003553	SnoaL-like domain; Region: SnoaL_2; pfam12680
1151116003554	Curli production assembly/transport component CsgG; Region: CsgG; cl17434
1151116003555	Type VIII secretion system (T8SS), CsgF protein; Region: CsgF; cl08082
1151116003556	Curli assembly protein CsgE; Region: CsgE; cl08115
1151116003557	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1151116003558	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116003559	DNA binding residues [nucleotide binding]
1151116003560	dimerization interface [polypeptide binding]; other site
1151116003561	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1151116003562	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1151116003563	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1151116003564	major curlin subunit; Provisional; Region: csgA; PRK10051
1151116003565	Thin aggregative fimbriae synthesis protein; Region: Tafi-CsgC; cl11667
1151116003566	High-affinity nickel-transport protein; Region: NicO; cl00964
1151116003567	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1151116003568	Acylphosphatase; Region: Acylphosphatase; pfam00708
1151116003569	HypF finger; Region: zf-HYPF; pfam07503
1151116003570	HypF finger; Region: zf-HYPF; pfam07503
1151116003571	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1151116003572	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
1151116003573	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1151116003574	[4Fe-4S] binding site [ion binding]; other site
1151116003575	molybdopterin cofactor binding site; other site
1151116003576	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1151116003577	molybdopterin cofactor binding site; other site
1151116003578	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1151116003579	4Fe-4S binding domain; Region: Fer4; cl02805
1151116003580	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1151116003581	nickel binding site [ion binding]; other site
1151116003582	Formate hydrogenlyase maturation protein HycH; Region: HycH; pfam07450
1151116003583	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1151116003584	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1151116003585	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1151116003586	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1151116003587	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1151116003588	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1151116003589	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1151116003590	NADH dehydrogenase; Region: NADHdh; cl00469
1151116003591	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1151116003592	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1151116003593	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1151116003594	Transcriptional repressor of hyc and hyp operons; Region: HycA_repressor; cl08095
1151116003595	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1151116003596	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1151116003597	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1151116003598	HupF/HypC family; Region: HupF_HypC; cl00394
1151116003599	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1151116003600	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1151116003601	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1151116003602	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1151116003603	dimerization interface [polypeptide binding]; other site
1151116003604	ATP binding site [chemical binding]; other site
1151116003605	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1151116003606	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1151116003607	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1151116003608	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116003609	Walker A motif; other site
1151116003610	ATP binding site [chemical binding]; other site
1151116003611	Walker B motif; other site
1151116003612	arginine finger; other site
1151116003613	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1151116003614	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1151116003615	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1151116003616	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1151116003617	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116003618	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116003619	dimerization interface [polypeptide binding]; other site
1151116003620	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; cl11635
1151116003621	potential frameshift: common BLAST hit: gi|322831895|ref|YP_004211922.1| Carboxymethylenebutenolidase
1151116003622	putative S-transferase; Provisional; Region: PRK11752
1151116003623	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1151116003624	C-terminal domain interface [polypeptide binding]; other site
1151116003625	GSH binding site (G-site) [chemical binding]; other site
1151116003626	dimer interface [polypeptide binding]; other site
1151116003627	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1151116003628	dimer interface [polypeptide binding]; other site
1151116003629	N-terminal domain interface [polypeptide binding]; other site
1151116003630	active site
1151116003631	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116003632	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116003633	DNA binding site [nucleotide binding]
1151116003634	domain linker motif; other site
1151116003635	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1151116003636	ligand binding site [chemical binding]; other site
1151116003637	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1151116003638	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1151116003639	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1151116003640	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1151116003641	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1151116003642	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1151116003643	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1151116003644	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1151116003645	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1151116003646	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1151116003647	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1151116003648	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116003649	Coenzyme A binding pocket [chemical binding]; other site
1151116003650	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
1151116003651	lipoprotein, YaeC family; Region: TIGR00363
1151116003652	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1151116003653	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1151116003654	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
1151116003655	Walker A/P-loop; other site
1151116003656	ATP binding site [chemical binding]; other site
1151116003657	Q-loop/lid; other site
1151116003658	ABC transporter signature motif; other site
1151116003659	Walker B; other site
1151116003660	D-loop; other site
1151116003661	H-loop/switch region; other site
1151116003662	heme exporter protein CcmB; Region: ccmB; TIGR01190
1151116003663	heme exporter protein CcmC; Region: ccmC; TIGR01191
1151116003664	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1151116003665	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
1151116003666	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
1151116003667	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
1151116003668	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1151116003669	Cytochrome C biogenesis protein; Region: CcmH; pfam03918
1151116003670	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
1151116003671	cytochrome c-type biogenesis protein CcmI; Region: cytochro_ccmI; TIGR03142
1151116003672	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1151116003673	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116003674	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116003675	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116003676	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1151116003677	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1151116003678	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1151116003679	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1151116003680	dimer interface [polypeptide binding]; other site
1151116003681	active site
1151116003682	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1151116003683	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1151116003684	substrate binding site [chemical binding]; other site
1151116003685	oxyanion hole (OAH) forming residues; other site
1151116003686	trimer interface [polypeptide binding]; other site
1151116003687	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1151116003688	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1151116003689	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1151116003690	catalytic core [active]
1151116003691	hypothetical protein; Provisional; Region: PRK04946
1151116003692	Smr domain; Region: Smr; pfam01713
1151116003693	HemK family putative methylases; Region: hemK_fam; TIGR00536
1151116003694	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116003695	S-adenosylmethionine binding site [chemical binding]; other site
1151116003696	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1151116003697	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1151116003698	Tetramer interface [polypeptide binding]; other site
1151116003699	active site
1151116003700	FMN-binding site [chemical binding]; other site
1151116003701	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1151116003702	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1151116003703	hypothetical protein; Provisional; Region: PRK10621
1151116003704	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1151116003705	Protein of unknown function, DUF462; Region: DUF462; cl01190
1151116003706	YfcL protein; Region: YfcL; pfam08891
1151116003707	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1151116003708	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1151116003709	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1151116003710	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1151116003711	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1151116003712	dimer interface [polypeptide binding]; other site
1151116003713	active site
1151116003714	Protein of unknown function (DUF2946); Region: DUF2946; pfam11162
1151116003715	potential frameshift: common BLAST hit: gi|322831942|ref|YP_004211969.1| iron-regulated membrane protein
1151116003716	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1151116003717	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1151116003718	transmembrane helices; other site
1151116003719	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116003720	DNA-binding site [nucleotide binding]; DNA binding site
1151116003721	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1151116003722	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116003723	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116003724	homodimer interface [polypeptide binding]; other site
1151116003725	catalytic residue [active]
1151116003726	Member of the Rhodanese Homology Domain superfamily. This CD includes the putative rhodanese-like protein, Psp2, of Yersinia pestis biovar Medievalis and other similar uncharacterized proteins; Region: RHOD_PspE2; cd01521
1151116003727	active site residue [active]
1151116003728	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1151116003729	EamA-like transporter family; Region: EamA; pfam00892
1151116003730	Cupin domain; Region: Cupin_2; pfam07883
1151116003731	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116003732	Helix-turn-helix domain; Region: HTH_18; pfam12833
1151116003733	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116003734	potential frameshift: common BLAST hit: gi|322831949|ref|YP_004211976.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein
1151116003735	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1151116003736	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1151116003737	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1151116003738	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1151116003739	dimerization interface 3.5A [polypeptide binding]; other site
1151116003740	active site
1151116003741	hypothetical protein; Provisional; Region: PRK10847
1151116003742	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1151116003743	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1151116003744	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1151116003745	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1151116003746	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1151116003747	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1151116003748	cell division protein DedD; Provisional; Region: PRK11633
1151116003749	Sporulation related domain; Region: SPOR; pfam05036
1151116003750	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1151116003751	colicin V production protein; Provisional; Region: PRK10845
1151116003752	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1151116003753	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1151116003754	active site
1151116003755	tetramer interface [polypeptide binding]; other site
1151116003756	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1151116003757	active site
1151116003758	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1151116003759	Flavoprotein; Region: Flavoprotein; pfam02441
1151116003760	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1151116003761	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116003762	substrate binding pocket [chemical binding]; other site
1151116003763	membrane-bound complex binding site; other site
1151116003764	hinge residues; other site
1151116003765	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116003766	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116003767	dimer interface [polypeptide binding]; other site
1151116003768	conserved gate region; other site
1151116003769	putative PBP binding loops; other site
1151116003770	ABC-ATPase subunit interface; other site
1151116003771	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116003772	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116003773	dimer interface [polypeptide binding]; other site
1151116003774	conserved gate region; other site
1151116003775	putative PBP binding loops; other site
1151116003776	ABC-ATPase subunit interface; other site
1151116003777	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1151116003778	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116003779	Walker A/P-loop; other site
1151116003780	ATP binding site [chemical binding]; other site
1151116003781	Q-loop/lid; other site
1151116003782	ABC transporter signature motif; other site
1151116003783	Walker B; other site
1151116003784	D-loop; other site
1151116003785	H-loop/switch region; other site
1151116003786	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1151116003787	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1151116003788	metal binding site [ion binding]; metal-binding site
1151116003789	dimer interface [polypeptide binding]; other site
1151116003790	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116003791	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1151116003792	peptide binding site [polypeptide binding]; other site
1151116003793	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1151116003794	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1151116003795	putative NAD(P) binding site [chemical binding]; other site
1151116003796	putative active site [active]
1151116003797	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1151116003798	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1151116003799	C-terminal domain interface [polypeptide binding]; other site
1151116003800	GSH binding site (G-site) [chemical binding]; other site
1151116003801	dimer interface [polypeptide binding]; other site
1151116003802	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1151116003803	N-terminal domain interface [polypeptide binding]; other site
1151116003804	putative dimer interface [polypeptide binding]; other site
1151116003805	active site
1151116003806	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1151116003807	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1151116003808	nudix motif; other site
1151116003809	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116003810	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116003811	DNA binding site [nucleotide binding]
1151116003812	domain linker motif; other site
1151116003813	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1151116003814	putative dimerization interface [polypeptide binding]; other site
1151116003815	putative ligand binding site [chemical binding]; other site
1151116003816	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1151116003817	active site
1151116003818	phosphorylation site [posttranslational modification]
1151116003819	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1151116003820	active site
1151116003821	P-loop; other site
1151116003822	phosphorylation site [posttranslational modification]
1151116003823	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1151116003824	transketolase; Reviewed; Region: PRK05899
1151116003825	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1151116003826	TPP-binding site [chemical binding]; other site
1151116003827	dimer interface [polypeptide binding]; other site
1151116003828	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1151116003829	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1151116003830	PYR/PP interface [polypeptide binding]; other site
1151116003831	dimer interface [polypeptide binding]; other site
1151116003832	TPP binding site [chemical binding]; other site
1151116003833	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1151116003834	phosphate acetyltransferase; Reviewed; Region: PRK05632
1151116003835	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1151116003836	DRTGG domain; Region: DRTGG; pfam07085
1151116003837	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
1151116003838	propionate/acetate kinase; Provisional; Region: PRK12379
1151116003839	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1151116003840	hypothetical protein; Provisional; Region: PRK01816
1151116003841	hypothetical protein; Validated; Region: PRK05445
1151116003842	putative phosphatase; Provisional; Region: PRK11587
1151116003843	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116003844	motif II; other site
1151116003845	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1151116003846	transmembrane helices; other site
1151116003847	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1151116003848	TrkA-C domain; Region: TrkA_C; pfam02080
1151116003849	TrkA-C domain; Region: TrkA_C; pfam02080
1151116003850	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1151116003851	5'-nucleotidase; Provisional; Region: PRK03826
1151116003852	aminotransferase AlaT; Validated; Region: PRK09265
1151116003853	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116003854	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116003855	homodimer interface [polypeptide binding]; other site
1151116003856	catalytic residue [active]
1151116003857	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1151116003858	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116003859	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1151116003860	putative dimerization interface [polypeptide binding]; other site
1151116003861	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1151116003862	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1151116003863	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1151116003864	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1151116003865	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1151116003866	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1151116003867	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1151116003868	putative dimer interface [polypeptide binding]; other site
1151116003869	[2Fe-2S] cluster binding site [ion binding]; other site
1151116003870	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1151116003871	SLBB domain; Region: SLBB; pfam10531
1151116003872	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1151116003873	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1151116003874	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1151116003875	catalytic loop [active]
1151116003876	iron binding site [ion binding]; other site
1151116003877	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1151116003878	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1151116003879	[4Fe-4S] binding site [ion binding]; other site
1151116003880	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1151116003881	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1151116003882	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1151116003883	4Fe-4S binding domain; Region: Fer4; pfam00037
1151116003884	4Fe-4S binding domain; Region: Fer4; pfam00037
1151116003885	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
1151116003886	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1151116003887	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1151116003888	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1151116003889	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1151116003890	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1151116003891	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1151116003892	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1151116003893	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1151116003894	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1151116003895	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1151116003896	hypothetical protein; Provisional; Region: PRK10404
1151116003897	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1151116003898	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1151116003899	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1151116003900	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1151116003901	dimer interface [polypeptide binding]; other site
1151116003902	tetramer interface [polypeptide binding]; other site
1151116003903	PYR/PP interface [polypeptide binding]; other site
1151116003904	TPP binding site [chemical binding]; other site
1151116003905	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1151116003906	TPP-binding site; other site
1151116003907	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1151116003908	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1151116003909	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1151116003910	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1151116003911	substrate binding site [chemical binding]; other site
1151116003912	oxyanion hole (OAH) forming residues; other site
1151116003913	trimer interface [polypeptide binding]; other site
1151116003914	O-succinylbenzoate synthase; Provisional; Region: PRK05105
1151116003915	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1151116003916	active site
1151116003917	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1151116003918	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1151116003919	acyl-activating enzyme (AAE) consensus motif; other site
1151116003920	putative AMP binding site [chemical binding]; other site
1151116003921	putative active site [active]
1151116003922	putative CoA binding site [chemical binding]; other site
1151116003923	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1151116003924	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1151116003925	tetramer interface [polypeptide binding]; other site
1151116003926	heme binding pocket [chemical binding]; other site
1151116003927	NADPH binding site [chemical binding]; other site
1151116003928	YfaZ precursor; Region: YfaZ; pfam07437
1151116003929	hypothetical protein; Provisional; Region: PRK03673
1151116003930	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1151116003931	putative MPT binding site; other site
1151116003932	Competence-damaged protein; Region: CinA; cl00666
1151116003933	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1151116003934	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1151116003935	catalytic loop [active]
1151116003936	iron binding site [ion binding]; other site
1151116003937	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1151116003938	dimer interface [polypeptide binding]; other site
1151116003939	putative radical transfer pathway; other site
1151116003940	diiron center [ion binding]; other site
1151116003941	tyrosyl radical; other site
1151116003942	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1151116003943	ATP cone domain; Region: ATP-cone; pfam03477
1151116003944	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1151116003945	active site
1151116003946	dimer interface [polypeptide binding]; other site
1151116003947	catalytic residues [active]
1151116003948	effector binding site; other site
1151116003949	R2 peptide binding site; other site
1151116003950	adhesin; Provisional; Region: PRK09752
1151116003951	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1151116003952	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1151116003953	Autotransporter beta-domain; Region: Autotransporter; smart00869
1151116003954	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1151116003955	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116003956	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1151116003957	DNA gyrase subunit A; Validated; Region: PRK05560
1151116003958	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1151116003959	CAP-like domain; other site
1151116003960	active site
1151116003961	primary dimer interface [polypeptide binding]; other site
1151116003962	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1151116003963	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1151116003964	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1151116003965	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1151116003966	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1151116003967	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1151116003968	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1151116003969	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116003970	dimer interface [polypeptide binding]; other site
1151116003971	phosphorylation site [posttranslational modification]
1151116003972	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116003973	ATP binding site [chemical binding]; other site
1151116003974	Mg2+ binding site [ion binding]; other site
1151116003975	G-X-G motif; other site
1151116003976	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1151116003977	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116003978	active site
1151116003979	phosphorylation site [posttranslational modification]
1151116003980	intermolecular recognition site; other site
1151116003981	dimerization interface [polypeptide binding]; other site
1151116003982	transcriptional regulator RcsB; Provisional; Region: PRK10840
1151116003983	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116003984	active site
1151116003985	phosphorylation site [posttranslational modification]
1151116003986	intermolecular recognition site; other site
1151116003987	dimerization interface [polypeptide binding]; other site
1151116003988	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116003989	DNA binding residues [nucleotide binding]
1151116003990	dimerization interface [polypeptide binding]; other site
1151116003991	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1151116003992	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116003993	ATP binding site [chemical binding]; other site
1151116003994	Mg2+ binding site [ion binding]; other site
1151116003995	G-X-G motif; other site
1151116003996	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1151116003997	putative binding surface; other site
1151116003998	active site
1151116003999	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004000	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1151116004001	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004002	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004003	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1151116004004	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1151116004005	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004006	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1151116004007	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004008	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004009	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1151116004010	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004011	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1151116004012	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004013	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1151116004014	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004015	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004016	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1151116004017	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1151116004018	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1151116004019	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1151116004020	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1151116004021	ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245
1151116004022	Walker A/P-loop; other site
1151116004023	ATP binding site [chemical binding]; other site
1151116004024	Q-loop/lid; other site
1151116004025	ABC transporter signature motif; other site
1151116004026	Walker B; other site
1151116004027	D-loop; other site
1151116004028	H-loop/switch region; other site
1151116004029	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1151116004030	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116004031	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
1151116004032	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1151116004033	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1151116004034	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1151116004035	trimer interface [polypeptide binding]; other site
1151116004036	eyelet of channel; other site
1151116004037	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1151116004038	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116004039	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1151116004040	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1151116004041	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1151116004042	DinI-like family; Region: DinI; pfam06183
1151116004043	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1151116004044	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1151116004045	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1151116004046	putative dimer interface [polypeptide binding]; other site
1151116004047	N-terminal domain interface [polypeptide binding]; other site
1151116004048	putative substrate binding pocket (H-site) [chemical binding]; other site
1151116004049	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1151116004050	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1151116004051	Sulfatase; Region: Sulfatase; cl17466
1151116004052	hypothetical protein; Provisional; Region: PRK13689
1151116004053	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1151116004054	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1151116004055	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1151116004056	5S rRNA interface [nucleotide binding]; other site
1151116004057	CTC domain interface [polypeptide binding]; other site
1151116004058	L16 interface [polypeptide binding]; other site
1151116004059	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1151116004060	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116004061	ATP binding site [chemical binding]; other site
1151116004062	putative Mg++ binding site [ion binding]; other site
1151116004063	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116004064	nucleotide binding region [chemical binding]; other site
1151116004065	ATP-binding site [chemical binding]; other site
1151116004066	Double zinc ribbon; Region: DZR; pfam12773
1151116004067	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1151116004068	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1151116004069	RNA binding surface [nucleotide binding]; other site
1151116004070	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1151116004071	active site
1151116004072	uracil binding [chemical binding]; other site
1151116004073	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116004074	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1151116004075	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116004076	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116004077	putative substrate translocation pore; other site
1151116004078	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1151116004079	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116004080	DNA binding site [nucleotide binding]
1151116004081	domain linker motif; other site
1151116004082	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1151116004083	putative ligand binding site [chemical binding]; other site
1151116004084	putative dimerization interface [polypeptide binding]; other site
1151116004085	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1151116004086	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1151116004087	NADP binding site [chemical binding]; other site
1151116004088	homodimer interface [polypeptide binding]; other site
1151116004089	active site
1151116004090	classical (c) SDRs; Region: SDR_c; cd05233
1151116004091	NAD(P) binding site [chemical binding]; other site
1151116004092	active site
1151116004093	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1151116004094	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1151116004095	Cytochrome c; Region: Cytochrom_C; pfam00034
1151116004096	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1151116004097	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1151116004098	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
1151116004099	hypothetical protein; Provisional; Region: PRK11835
1151116004100	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1151116004101	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116004102	Walker A/P-loop; other site
1151116004103	ATP binding site [chemical binding]; other site
1151116004104	Q-loop/lid; other site
1151116004105	ABC transporter signature motif; other site
1151116004106	Walker B; other site
1151116004107	D-loop; other site
1151116004108	H-loop/switch region; other site
1151116004109	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116004110	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116004111	Walker A/P-loop; other site
1151116004112	ATP binding site [chemical binding]; other site
1151116004113	Q-loop/lid; other site
1151116004114	ABC transporter signature motif; other site
1151116004115	Walker B; other site
1151116004116	D-loop; other site
1151116004117	H-loop/switch region; other site
1151116004118	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116004119	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
1151116004120	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004121	dimer interface [polypeptide binding]; other site
1151116004122	conserved gate region; other site
1151116004123	ABC-ATPase subunit interface; other site
1151116004124	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1151116004125	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004126	dimer interface [polypeptide binding]; other site
1151116004127	conserved gate region; other site
1151116004128	putative PBP binding loops; other site
1151116004129	ABC-ATPase subunit interface; other site
1151116004130	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1151116004131	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1151116004132	phage resistance protein; Provisional; Region: PRK10551
1151116004133	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1151116004134	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116004135	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1151116004136	NlpC/P60 family; Region: NLPC_P60; pfam00877
1151116004137	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1151116004138	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1151116004139	active site
1151116004140	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1151116004141	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1151116004142	Domain of unknown function (DUF3536); Region: DUF3536; pfam12055
1151116004143	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1151116004144	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116004145	DNA-binding site [nucleotide binding]; DNA binding site
1151116004146	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1151116004147	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1151116004148	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1151116004149	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1151116004150	elongation factor P; Provisional; Region: PRK04542
1151116004151	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1151116004152	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1151116004153	RNA binding site [nucleotide binding]; other site
1151116004154	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1151116004155	RNA binding site [nucleotide binding]; other site
1151116004156	Flagellin N-methylase; Region: FliB; cl00497
1151116004157	sugar efflux transporter B; Provisional; Region: PRK15011
1151116004158	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116004159	putative substrate translocation pore; other site
1151116004160	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1151116004161	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1151116004162	active site
1151116004163	phosphorylation site [posttranslational modification]
1151116004164	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
1151116004165	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1151116004166	dimerization domain swap beta strand [polypeptide binding]; other site
1151116004167	regulatory protein interface [polypeptide binding]; other site
1151116004168	active site
1151116004169	regulatory phosphorylation site [posttranslational modification]; other site
1151116004170	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1151116004171	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1151116004172	putative substrate binding site [chemical binding]; other site
1151116004173	putative ATP binding site [chemical binding]; other site
1151116004174	potential frameshift: common BLAST hit: gi|322832060|ref|YP_004212087.1| PTS system fructose subfamily transporter subunit IIC
1151116004175	endonuclease IV; Provisional; Region: PRK01060
1151116004176	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1151116004177	AP (apurinic/apyrimidinic) site pocket; other site
1151116004178	DNA interaction; other site
1151116004179	Metal-binding active site; metal-binding site
1151116004180	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1151116004181	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1151116004182	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116004183	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1151116004184	putative dimerization interface [polypeptide binding]; other site
1151116004185	lysine transporter; Provisional; Region: PRK10836
1151116004186	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1151116004187	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1151116004188	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116004189	ABC-ATPase subunit  interface; other site
1151116004190	dimer interface [polypeptide binding]; other site
1151116004191	putative PBP binding regions; other site
1151116004192	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1151116004193	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1151116004194	Walker A/P-loop; other site
1151116004195	ATP binding site [chemical binding]; other site
1151116004196	Q-loop/lid; other site
1151116004197	ABC transporter signature motif; other site
1151116004198	Walker B; other site
1151116004199	D-loop; other site
1151116004200	H-loop/switch region; other site
1151116004201	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116004202	active site
1151116004203	motif I; other site
1151116004204	motif II; other site
1151116004205	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1151116004206	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1151116004207	trimer interface [polypeptide binding]; other site
1151116004208	eyelet of channel; other site
1151116004209	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1151116004210	DEAD_2; Region: DEAD_2; pfam06733
1151116004211	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1151116004212	glycosyl transferase family protein; Provisional; Region: PRK08136
1151116004213	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1151116004214	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1151116004215	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1151116004216	PhnA protein; Region: PhnA; pfam03831
1151116004217	Peptidase M3-like family, a zincin metallopeptidase, includes M3 and M32 families; Region: M3_like; cd06258
1151116004218	active site
1151116004219	Zn binding site [ion binding]; other site
1151116004220	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1151116004221	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1151116004222	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116004223	S-adenosylmethionine binding site [chemical binding]; other site
1151116004224	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116004225	PAS domain; Region: PAS_9; pfam13426
1151116004226	putative active site [active]
1151116004227	heme pocket [chemical binding]; other site
1151116004228	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116004229	PAS domain; Region: PAS_9; pfam13426
1151116004230	putative active site [active]
1151116004231	heme pocket [chemical binding]; other site
1151116004232	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1151116004233	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116004234	dimer interface [polypeptide binding]; other site
1151116004235	putative CheW interface [polypeptide binding]; other site
1151116004236	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1151116004237	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116004238	Walker A/P-loop; other site
1151116004239	ATP binding site [chemical binding]; other site
1151116004240	Q-loop/lid; other site
1151116004241	ABC transporter signature motif; other site
1151116004242	Walker B; other site
1151116004243	D-loop; other site
1151116004244	H-loop/switch region; other site
1151116004245	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116004246	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004247	dimer interface [polypeptide binding]; other site
1151116004248	conserved gate region; other site
1151116004249	putative PBP binding loops; other site
1151116004250	ABC-ATPase subunit interface; other site
1151116004251	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1151116004252	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116004253	substrate binding pocket [chemical binding]; other site
1151116004254	membrane-bound complex binding site; other site
1151116004255	hinge residues; other site
1151116004256	hypothetical protein; Provisional; Region: PRK11019
1151116004257	polysaccharide export inner-membrane protein, BexC/CtrB/KpsE family; Region: BexC_CtrB_KpsE; TIGR01010
1151116004258	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1151116004259	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
1151116004260	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsC; COG3563
1151116004261	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
1151116004262	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
1151116004263	Right handed beta helix region; Region: Beta_helix; pfam13229
1151116004264	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
1151116004265	accessory Sec system protein Asp2; Region: acc_sec_asp2; TIGR03712
1151116004266	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1151116004267	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1151116004268	Protein of unknown function (DUF3184); Region: DUF3184; pfam11380
1151116004269	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1151116004270	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1151116004271	Walker A/P-loop; other site
1151116004272	ATP binding site [chemical binding]; other site
1151116004273	Q-loop/lid; other site
1151116004274	ABC transporter signature motif; other site
1151116004275	Walker B; other site
1151116004276	D-loop; other site
1151116004277	H-loop/switch region; other site
1151116004278	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1151116004279	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1151116004280	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1151116004281	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1151116004282	dimerization interface [polypeptide binding]; other site
1151116004283	DPS ferroxidase diiron center [ion binding]; other site
1151116004284	ion pore; other site
1151116004285	putative anti-sigmaE protein; Provisional; Region: PRK13920
1151116004286	Anti-sigma-K factor rskA; Region: RskA; pfam10099
1151116004287	RNA polymerase sigma factor; Provisional; Region: PRK11924
1151116004288	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1151116004289	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1151116004290	DNA binding residues [nucleotide binding]
1151116004291	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
1151116004292	Fasciclin domain; Region: Fasciclin; pfam02469
1151116004293	threonine and homoserine efflux system; Provisional; Region: PRK10532
1151116004294	EamA-like transporter family; Region: EamA; pfam00892
1151116004295	outer membrane protein X; Provisional; Region: ompX; PRK09408
1151116004296	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
1151116004297	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1151116004298	Moco binding site; other site
1151116004299	metal coordination site [ion binding]; other site
1151116004300	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1151116004301	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
1151116004302	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116004303	active site
1151116004304	phosphorylation site [posttranslational modification]
1151116004305	intermolecular recognition site; other site
1151116004306	dimerization interface [polypeptide binding]; other site
1151116004307	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116004308	DNA binding site [nucleotide binding]
1151116004309	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1151116004310	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116004311	dimerization interface [polypeptide binding]; other site
1151116004312	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116004313	dimer interface [polypeptide binding]; other site
1151116004314	phosphorylation site [posttranslational modification]
1151116004315	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116004316	ATP binding site [chemical binding]; other site
1151116004317	Mg2+ binding site [ion binding]; other site
1151116004318	G-X-G motif; other site
1151116004319	phosphoethanolamine transferase; Provisional; Region: PRK11560
1151116004320	Sulfatase; Region: Sulfatase; pfam00884
1151116004321	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1151116004322	putative catalytic site [active]
1151116004323	putative metal binding site [ion binding]; other site
1151116004324	putative phosphate binding site [ion binding]; other site
1151116004325	transcriptional activator TtdR; Provisional; Region: PRK09801
1151116004326	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116004327	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1151116004328	putative effector binding pocket; other site
1151116004329	putative dimerization interface [polypeptide binding]; other site
1151116004330	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1151116004331	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1151116004332	substrate binding site [chemical binding]; other site
1151116004333	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1151116004334	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1151116004335	substrate binding site [chemical binding]; other site
1151116004336	ligand binding site [chemical binding]; other site
1151116004337	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1151116004338	choline transport protein BetT; Provisional; Region: PRK09928
1151116004339	transcriptional regulator BetI; Validated; Region: PRK00767
1151116004340	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116004341	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1151116004342	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
1151116004343	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
1151116004344	tetrameric interface [polypeptide binding]; other site
1151116004345	NAD binding site [chemical binding]; other site
1151116004346	catalytic residues [active]
1151116004347	choline dehydrogenase; Validated; Region: PRK02106
1151116004348	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1151116004349	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116004350	Coenzyme A binding pocket [chemical binding]; other site
1151116004351	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116004352	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116004353	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116004354	putative effector binding pocket; other site
1151116004355	dimerization interface [polypeptide binding]; other site
1151116004356	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1151116004357	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1151116004358	RES domain; Region: RES; cl02411
1151116004359	Protein of unknown function (DUF2384); Region: DUF2384; cl17718
1151116004360	putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293
1151116004361	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1151116004362	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1151116004363	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116004364	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116004365	Walker A/P-loop; other site
1151116004366	ATP binding site [chemical binding]; other site
1151116004367	ABC transporter signature motif; other site
1151116004368	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116004369	Walker B; other site
1151116004370	ABC transporter; Region: ABC_tran_2; pfam12848
1151116004371	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116004372	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1151116004373	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1151116004374	ATP binding site [chemical binding]; other site
1151116004375	substrate interface [chemical binding]; other site
1151116004376	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1151116004377	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1151116004378	dimer interface [polypeptide binding]; other site
1151116004379	putative functional site; other site
1151116004380	putative MPT binding site; other site
1151116004381	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1151116004382	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1151116004383	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
1151116004384	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1151116004385	Autotransporter beta-domain; Region: Autotransporter; smart00869
1151116004386	putative transporter; Provisional; Region: PRK03699
1151116004387	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116004388	putative substrate translocation pore; other site
1151116004389	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1151116004390	catalytic nucleophile [active]
1151116004391	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1151116004392	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116004393	Walker A/P-loop; other site
1151116004394	ATP binding site [chemical binding]; other site
1151116004395	Q-loop/lid; other site
1151116004396	ABC transporter signature motif; other site
1151116004397	Walker B; other site
1151116004398	D-loop; other site
1151116004399	H-loop/switch region; other site
1151116004400	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116004401	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116004402	Walker A/P-loop; other site
1151116004403	ATP binding site [chemical binding]; other site
1151116004404	Q-loop/lid; other site
1151116004405	ABC transporter signature motif; other site
1151116004406	Walker B; other site
1151116004407	D-loop; other site
1151116004408	H-loop/switch region; other site
1151116004409	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116004410	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1151116004411	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1151116004412	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1151116004413	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004414	dimer interface [polypeptide binding]; other site
1151116004415	conserved gate region; other site
1151116004416	putative PBP binding loops; other site
1151116004417	ABC-ATPase subunit interface; other site
1151116004418	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1151116004419	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1151116004420	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004421	dimer interface [polypeptide binding]; other site
1151116004422	conserved gate region; other site
1151116004423	putative PBP binding loops; other site
1151116004424	ABC-ATPase subunit interface; other site
1151116004425	S-formylglutathione hydrolase; Region: PLN02442
1151116004426	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1151116004427	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1151116004428	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1151116004429	substrate binding site [chemical binding]; other site
1151116004430	catalytic Zn binding site [ion binding]; other site
1151116004431	NAD binding site [chemical binding]; other site
1151116004432	structural Zn binding site [ion binding]; other site
1151116004433	dimer interface [polypeptide binding]; other site
1151116004434	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116004435	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116004436	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1151116004437	putative dimerization interface [polypeptide binding]; other site
1151116004438	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116004439	putative substrate translocation pore; other site
1151116004440	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
1151116004441	active site
1151116004442	Predicted membrane protein [Function unknown]; Region: COG2311
1151116004443	hypothetical protein; Provisional; Region: PRK10835
1151116004444	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1151116004445	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116004446	DNA binding site [nucleotide binding]
1151116004447	domain linker motif; other site
1151116004448	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1151116004449	dimerization interface (closed form) [polypeptide binding]; other site
1151116004450	ligand binding site [chemical binding]; other site
1151116004451	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1151116004452	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1151116004453	ligand binding site [chemical binding]; other site
1151116004454	calcium binding site [ion binding]; other site
1151116004455	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116004456	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1151116004457	Walker A/P-loop; other site
1151116004458	ATP binding site [chemical binding]; other site
1151116004459	Q-loop/lid; other site
1151116004460	ABC transporter signature motif; other site
1151116004461	Walker B; other site
1151116004462	D-loop; other site
1151116004463	H-loop/switch region; other site
1151116004464	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116004465	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116004466	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116004467	TM-ABC transporter signature motif; other site
1151116004468	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1151116004469	putative active site [active]
1151116004470	malate dehydrogenase; Provisional; Region: PRK13529
1151116004471	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1151116004472	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1151116004473	NAD(P) binding site [chemical binding]; other site
1151116004474	cytidine deaminase; Provisional; Region: PRK09027
1151116004475	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1151116004476	active site
1151116004477	catalytic motif [active]
1151116004478	Zn binding site [ion binding]; other site
1151116004479	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1151116004480	active site
1151116004481	catalytic motif [active]
1151116004482	Zn binding site [ion binding]; other site
1151116004483	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1151116004484	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116004485	substrate binding pocket [chemical binding]; other site
1151116004486	membrane-bound complex binding site; other site
1151116004487	hinge residues; other site
1151116004488	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004489	dimer interface [polypeptide binding]; other site
1151116004490	conserved gate region; other site
1151116004491	putative PBP binding loops; other site
1151116004492	ABC-ATPase subunit interface; other site
1151116004493	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116004494	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004495	dimer interface [polypeptide binding]; other site
1151116004496	conserved gate region; other site
1151116004497	putative PBP binding loops; other site
1151116004498	ABC-ATPase subunit interface; other site
1151116004499	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1151116004500	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116004501	substrate binding pocket [chemical binding]; other site
1151116004502	membrane-bound complex binding site; other site
1151116004503	hinge residues; other site
1151116004504	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1151116004505	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116004506	Walker A/P-loop; other site
1151116004507	ATP binding site [chemical binding]; other site
1151116004508	Q-loop/lid; other site
1151116004509	ABC transporter signature motif; other site
1151116004510	Walker B; other site
1151116004511	D-loop; other site
1151116004512	H-loop/switch region; other site
1151116004513	putative lipoprotein; Provisional; Region: PRK10533
1151116004514	hypothetical protein; Provisional; Region: PRK02877
1151116004515	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1151116004516	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1151116004517	amidase catalytic site [active]
1151116004518	Zn binding residues [ion binding]; other site
1151116004519	substrate binding site [chemical binding]; other site
1151116004520	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1151116004521	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116004522	NAD(P) binding site [chemical binding]; other site
1151116004523	active site
1151116004524	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1151116004525	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1151116004526	putative NAD(P) binding site [chemical binding]; other site
1151116004527	putative active site [active]
1151116004528	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1151116004529	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1151116004530	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1151116004531	tetramer interface [polypeptide binding]; other site
1151116004532	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116004533	catalytic residue [active]
1151116004534	pyruvate dehydrogenase; Provisional; Region: PRK09124
1151116004535	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1151116004536	PYR/PP interface [polypeptide binding]; other site
1151116004537	dimer interface [polypeptide binding]; other site
1151116004538	tetramer interface [polypeptide binding]; other site
1151116004539	TPP binding site [chemical binding]; other site
1151116004540	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1151116004541	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1151116004542	TPP-binding site [chemical binding]; other site
1151116004543	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1151116004544	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1151116004545	FAD binding pocket [chemical binding]; other site
1151116004546	FAD binding motif [chemical binding]; other site
1151116004547	phosphate binding motif [ion binding]; other site
1151116004548	beta-alpha-beta structure motif; other site
1151116004549	NAD binding pocket [chemical binding]; other site
1151116004550	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1151116004551	catalytic loop [active]
1151116004552	iron binding site [ion binding]; other site
1151116004553	hybrid cluster protein; Provisional; Region: PRK05290
1151116004554	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1151116004555	ACS interaction site; other site
1151116004556	CODH interaction site; other site
1151116004557	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1151116004558	hybrid metal cluster; other site
1151116004559	Predicted membrane protein [Function unknown]; Region: COG2431
1151116004560	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1151116004561	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1151116004562	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1151116004563	putative active site [active]
1151116004564	putative metal-binding site [ion binding]; other site
1151116004565	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1151116004566	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1151116004567	DNA-binding site [nucleotide binding]; DNA binding site
1151116004568	RNA-binding motif; other site
1151116004569	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1151116004570	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1151116004571	Clp amino terminal domain; Region: Clp_N; pfam02861
1151116004572	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116004573	Walker A motif; other site
1151116004574	ATP binding site [chemical binding]; other site
1151116004575	Walker B motif; other site
1151116004576	arginine finger; other site
1151116004577	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116004578	Walker A motif; other site
1151116004579	ATP binding site [chemical binding]; other site
1151116004580	Walker B motif; other site
1151116004581	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1151116004582	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1151116004583	rRNA binding site [nucleotide binding]; other site
1151116004584	predicted 30S ribosome binding site; other site
1151116004585	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1151116004586	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1151116004587	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1151116004588	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116004589	Walker A/P-loop; other site
1151116004590	ATP binding site [chemical binding]; other site
1151116004591	Q-loop/lid; other site
1151116004592	ABC transporter signature motif; other site
1151116004593	Walker B; other site
1151116004594	D-loop; other site
1151116004595	H-loop/switch region; other site
1151116004596	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1151116004597	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1151116004598	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116004599	Walker A/P-loop; other site
1151116004600	ATP binding site [chemical binding]; other site
1151116004601	Q-loop/lid; other site
1151116004602	ABC transporter signature motif; other site
1151116004603	Walker B; other site
1151116004604	D-loop; other site
1151116004605	H-loop/switch region; other site
1151116004606	thioredoxin reductase; Provisional; Region: PRK10262
1151116004607	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1151116004608	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1151116004609	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1151116004610	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116004611	putative DNA binding site [nucleotide binding]; other site
1151116004612	putative Zn2+ binding site [ion binding]; other site
1151116004613	AsnC family; Region: AsnC_trans_reg; pfam01037
1151116004614	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1151116004615	DNA translocase FtsK; Provisional; Region: PRK10263
1151116004616	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1151116004617	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1151116004618	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1151116004619	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1151116004620	recombination factor protein RarA; Reviewed; Region: PRK13342
1151116004621	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116004622	Walker A motif; other site
1151116004623	ATP binding site [chemical binding]; other site
1151116004624	Walker B motif; other site
1151116004625	arginine finger; other site
1151116004626	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1151116004627	seryl-tRNA synthetase; Provisional; Region: PRK05431
1151116004628	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1151116004629	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1151116004630	dimer interface [polypeptide binding]; other site
1151116004631	active site
1151116004632	motif 1; other site
1151116004633	motif 2; other site
1151116004634	motif 3; other site
1151116004635	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116004636	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116004637	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116004638	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1151116004639	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1151116004640	putative [Fe4-S4] binding site [ion binding]; other site
1151116004641	putative molybdopterin cofactor binding site [chemical binding]; other site
1151116004642	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1151116004643	putative molybdopterin cofactor binding site; other site
1151116004644	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1151116004645	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1151116004646	putative [Fe4-S4] binding site [ion binding]; other site
1151116004647	putative molybdopterin cofactor binding site [chemical binding]; other site
1151116004648	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1151116004649	putative molybdopterin cofactor binding site; other site
1151116004650	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1151116004651	4Fe-4S binding domain; Region: Fer4; cl02805
1151116004652	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1151116004653	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1151116004654	ferredoxin-type protein NapF; Region: napF; TIGR00402
1151116004655	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1151116004656	putative MFS family transporter protein; Provisional; Region: PRK03633
1151116004657	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116004658	putative substrate translocation pore; other site
1151116004659	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1151116004660	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116004661	FeS/SAM binding site; other site
1151116004662	integrase; Provisional; Region: int; PHA02601
1151116004663	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1151116004664	active site
1151116004665	DNA binding site [nucleotide binding]
1151116004666	Int/Topo IB signature motif; other site
1151116004667	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116004668	non-specific DNA binding site [nucleotide binding]; other site
1151116004669	salt bridge; other site
1151116004670	sequence-specific DNA binding site [nucleotide binding]; other site
1151116004671	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
1151116004672	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1151116004673	DksA-like zinc finger domain containing protein; Region: PHA00080
1151116004674	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1151116004675	Beta protein; Region: Beta_protein; pfam14350
1151116004676	portal vertex protein; Provisional; Region: Q; PHA02536
1151116004677	Phage portal protein; Region: Phage_portal; pfam04860
1151116004678	terminase ATPase subunit; Provisional; Region: P; PHA02535
1151116004679	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1151116004680	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1151116004681	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1151116004682	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1151116004683	capsid protein; Provisional; Region: N; PHA02538
1151116004684	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1151116004685	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1151116004686	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1151116004687	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1151116004688	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1151116004689	catalytic residues [active]
1151116004690	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1151116004691	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1151116004692	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1151116004693	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116004694	AAA domain; Region: AAA_22; pfam13401
1151116004695	Walker A motif; other site
1151116004696	ATP binding site [chemical binding]; other site
1151116004697	Walker B motif; other site
1151116004698	arginine finger; other site
1151116004699	Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain [Function unknown]; Region: COG4916
1151116004700	TIR domain; Region: TIR_2; pfam13676
1151116004701	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1151116004702	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1151116004703	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1151116004704	baseplate assembly protein; Provisional; Region: J; PHA02568
1151116004705	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684
1151116004706	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1151116004707	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1151116004708	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1151116004709	major tail sheath protein; Provisional; Region: FI; PHA02560
1151116004710	major tail tube protein; Provisional; Region: FII; PHA02600
1151116004711	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1151116004712	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1151116004713	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1151116004714	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1151116004715	tail protein; Provisional; Region: D; PHA02561
1151116004716	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1151116004717	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1151116004718	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1151116004719	Pyruvate formate lyase 1; Region: PFL1; cd01678
1151116004720	coenzyme A binding site [chemical binding]; other site
1151116004721	active site
1151116004722	catalytic residues [active]
1151116004723	glycine loop; other site
1151116004724	formate transporter; Provisional; Region: PRK10805
1151116004725	uncharacterized domain; Region: TIGR00702
1151116004726	YcaO-like family; Region: YcaO; pfam02624
1151116004727	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1151116004728	homodimer interface [polypeptide binding]; other site
1151116004729	substrate-cofactor binding pocket; other site
1151116004730	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116004731	catalytic residue [active]
1151116004732	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1151116004733	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1151116004734	hinge; other site
1151116004735	active site
1151116004736	cytidylate kinase; Provisional; Region: cmk; PRK00023
1151116004737	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1151116004738	CMP-binding site; other site
1151116004739	The sites determining sugar specificity; other site
1151116004740	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1151116004741	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1151116004742	RNA binding site [nucleotide binding]; other site
1151116004743	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1151116004744	RNA binding site [nucleotide binding]; other site
1151116004745	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1151116004746	RNA binding site [nucleotide binding]; other site
1151116004747	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1151116004748	RNA binding site [nucleotide binding]; other site
1151116004749	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1151116004750	RNA binding site [nucleotide binding]; other site
1151116004751	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1151116004752	RNA binding site [nucleotide binding]; other site
1151116004753	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1151116004754	IHF dimer interface [polypeptide binding]; other site
1151116004755	IHF - DNA interface [nucleotide binding]; other site
1151116004756	ComEC family competence protein; Provisional; Region: PRK11539
1151116004757	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1151116004758	Competence protein; Region: Competence; pfam03772
1151116004759	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1151116004760	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1151116004761	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1151116004762	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1151116004763	Walker A/P-loop; other site
1151116004764	ATP binding site [chemical binding]; other site
1151116004765	Q-loop/lid; other site
1151116004766	ABC transporter signature motif; other site
1151116004767	Walker B; other site
1151116004768	D-loop; other site
1151116004769	H-loop/switch region; other site
1151116004770	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1151116004771	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1151116004772	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1151116004773	DNA-binding site [nucleotide binding]; DNA binding site
1151116004774	RNA-binding motif; other site
1151116004775	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1151116004776	DNA-binding site [nucleotide binding]; DNA binding site
1151116004777	RNA-binding motif; other site
1151116004778	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1151116004779	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1151116004780	Trm112p-like protein; Region: Trm112p; cl01066
1151116004781	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1151116004782	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1151116004783	Ligand binding site; other site
1151116004784	oligomer interface; other site
1151116004785	hypothetical protein; Provisional; Region: PRK10593
1151116004786	Phosphotransferase enzyme family; Region: APH; pfam01636
1151116004787	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1151116004788	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1151116004789	putative active site [active]
1151116004790	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1151116004791	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116004792	S-adenosylmethionine binding site [chemical binding]; other site
1151116004793	condesin subunit F; Provisional; Region: PRK05260
1151116004794	condesin subunit E; Provisional; Region: PRK05256
1151116004795	cell division protein MukB; Provisional; Region: mukB; PRK04863
1151116004796	MukB N-terminal; Region: MukB; pfam04310
1151116004797	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1151116004798	murein L,D-transpeptidase; Provisional; Region: PRK10594
1151116004799	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1151116004800	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1151116004801	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1151116004802	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1151116004803	Peptidase M15; Region: Peptidase_M15_3; cl01194
1151116004804	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1151116004805	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1151116004806	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116004807	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116004808	homodimer interface [polypeptide binding]; other site
1151116004809	catalytic residue [active]
1151116004810	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1151116004811	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1151116004812	trimer interface [polypeptide binding]; other site
1151116004813	eyelet of channel; other site
1151116004814	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1151116004815	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1151116004816	putative dimer interface [polypeptide binding]; other site
1151116004817	putative anticodon binding site; other site
1151116004818	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1151116004819	homodimer interface [polypeptide binding]; other site
1151116004820	motif 1; other site
1151116004821	motif 2; other site
1151116004822	active site
1151116004823	motif 3; other site
1151116004824	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1151116004825	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1151116004826	active site
1151116004827	aminopeptidase N; Provisional; Region: pepN; PRK14015
1151116004828	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1151116004829	active site
1151116004830	Zn binding site [ion binding]; other site
1151116004831	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1151116004832	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1151116004833	Walker A/P-loop; other site
1151116004834	ATP binding site [chemical binding]; other site
1151116004835	Q-loop/lid; other site
1151116004836	ABC transporter signature motif; other site
1151116004837	Walker B; other site
1151116004838	D-loop; other site
1151116004839	H-loop/switch region; other site
1151116004840	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1151116004841	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004842	dimer interface [polypeptide binding]; other site
1151116004843	conserved gate region; other site
1151116004844	putative PBP binding loops; other site
1151116004845	ABC-ATPase subunit interface; other site
1151116004846	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
1151116004847	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1151116004848	active site
1151116004849	dimer interface [polypeptide binding]; other site
1151116004850	non-prolyl cis peptide bond; other site
1151116004851	insertion regions; other site
1151116004852	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1151116004853	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116004854	substrate binding pocket [chemical binding]; other site
1151116004855	membrane-bound complex binding site; other site
1151116004856	hinge residues; other site
1151116004857	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
1151116004858	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1151116004859	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1151116004860	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1151116004861	quinone interaction residues [chemical binding]; other site
1151116004862	active site
1151116004863	catalytic residues [active]
1151116004864	FMN binding site [chemical binding]; other site
1151116004865	substrate binding site [chemical binding]; other site
1151116004866	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1151116004867	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1151116004868	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1151116004869	MOSC domain; Region: MOSC; pfam03473
1151116004870	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1151116004871	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1151116004872	catalytic loop [active]
1151116004873	iron binding site [ion binding]; other site
1151116004874	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1151116004875	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1151116004876	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1151116004877	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116004878	S-adenosylmethionine binding site [chemical binding]; other site
1151116004879	ABC transporter ATPase component; Reviewed; Region: PRK11147
1151116004880	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116004881	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116004882	ABC transporter; Region: ABC_tran_2; pfam12848
1151116004883	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116004884	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1151116004885	Paraquat-inducible protein A; Region: PqiA; pfam04403
1151116004886	Paraquat-inducible protein A; Region: PqiA; pfam04403
1151116004887	paraquat-inducible protein B; Provisional; Region: PRK10807
1151116004888	mce related protein; Region: MCE; pfam02470
1151116004889	mce related protein; Region: MCE; pfam02470
1151116004890	mce related protein; Region: MCE; pfam02470
1151116004891	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1151116004892	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1151116004893	ribosome modulation factor; Provisional; Region: PRK14563
1151116004894	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1151116004895	active site 1 [active]
1151116004896	dimer interface [polypeptide binding]; other site
1151116004897	active site 2 [active]
1151116004898	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1151116004899	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1151116004900	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1151116004901	outer membrane protein A; Reviewed; Region: PRK10808
1151116004902	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1151116004903	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1151116004904	ligand binding site [chemical binding]; other site
1151116004905	SOS cell division inhibitor; Provisional; Region: PRK10595
1151116004906	TfoX N-terminal domain; Region: TfoX_N; pfam04993
1151116004907	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1151116004908	TIGR01666 family membrane protein; Region: YCCS
1151116004909	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1151116004910	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1151116004911	Predicted membrane protein [Function unknown]; Region: COG3304
1151116004912	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1151116004913	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1151116004914	DNA helicase IV; Provisional; Region: helD; PRK11054
1151116004915	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1151116004916	Part of AAA domain; Region: AAA_19; pfam13245
1151116004917	Family description; Region: UvrD_C_2; pfam13538
1151116004918	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1151116004919	active site
1151116004920	dimer interfaces [polypeptide binding]; other site
1151116004921	catalytic residues [active]
1151116004922	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
1151116004923	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1151116004924	heat shock protein HspQ; Provisional; Region: PRK14129
1151116004925	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1151116004926	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1151116004927	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1151116004928	putative RNA binding site [nucleotide binding]; other site
1151116004929	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116004930	S-adenosylmethionine binding site [chemical binding]; other site
1151116004931	acylphosphatase; Provisional; Region: PRK14426
1151116004932	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1151116004933	sulfur relay protein, TusE/DsrC/DsvC family; Region: dsrC_tusE_dsvC; TIGR03342
1151116004934	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1151116004935	YccA-like proteins; Region: YccA_like; cd10433
1151116004936	Cupin; Region: Cupin_6; pfam12852
1151116004937	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116004938	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116004939	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116004940	atypical (a) SDRs, subgroup 7; Region: SDR_a7; cd05262
1151116004941	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1151116004942	putative NAD(P) binding site [chemical binding]; other site
1151116004943	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1151116004944	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1151116004945	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1151116004946	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004947	dimer interface [polypeptide binding]; other site
1151116004948	conserved gate region; other site
1151116004949	ABC-ATPase subunit interface; other site
1151116004950	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116004951	dimer interface [polypeptide binding]; other site
1151116004952	conserved gate region; other site
1151116004953	putative PBP binding loops; other site
1151116004954	ABC-ATPase subunit interface; other site
1151116004955	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1151116004956	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1151116004957	Walker A/P-loop; other site
1151116004958	ATP binding site [chemical binding]; other site
1151116004959	Q-loop/lid; other site
1151116004960	ABC transporter signature motif; other site
1151116004961	Walker B; other site
1151116004962	D-loop; other site
1151116004963	H-loop/switch region; other site
1151116004964	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1151116004965	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1151116004966	dimer interface [polypeptide binding]; other site
1151116004967	ligand binding site [chemical binding]; other site
1151116004968	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116004969	dimerization interface [polypeptide binding]; other site
1151116004970	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116004971	dimer interface [polypeptide binding]; other site
1151116004972	putative CheW interface [polypeptide binding]; other site
1151116004973	Uncharacterized protein containing double-stranded beta helix domain [Function unknown]; Region: COG4297
1151116004974	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1151116004975	potassium/proton antiporter; Reviewed; Region: PRK05326
1151116004976	TrkA-C domain; Region: TrkA_C; pfam02080
1151116004977	Transporter associated domain; Region: CorC_HlyC; smart01091
1151116004978	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1151116004979	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1151116004980	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1151116004981	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116004982	non-specific DNA binding site [nucleotide binding]; other site
1151116004983	salt bridge; other site
1151116004984	sequence-specific DNA binding site [nucleotide binding]; other site
1151116004985	Cupin domain; Region: Cupin_2; pfam07883
1151116004986	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
1151116004987	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1151116004988	catalytic triad [active]
1151116004989	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1151116004990	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1151116004991	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1151116004992	exonuclease I; Provisional; Region: sbcB; PRK11779
1151116004993	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1151116004994	active site
1151116004995	catalytic site [active]
1151116004996	substrate binding site [chemical binding]; other site
1151116004997	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1151116004998	hypothetical protein; Provisional; Region: PRK05423
1151116004999	Putative D-3-Phosphoglycerate Dehydrogenases; Region: PGDH_like_1; cd12169
1151116005000	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1151116005001	dimerization interface [polypeptide binding]; other site
1151116005002	NAD binding site [chemical binding]; other site
1151116005003	ligand binding site [chemical binding]; other site
1151116005004	catalytic site [active]
1151116005005	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1151116005006	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1151116005007	Walker A/P-loop; other site
1151116005008	ATP binding site [chemical binding]; other site
1151116005009	Q-loop/lid; other site
1151116005010	ABC transporter signature motif; other site
1151116005011	Walker B; other site
1151116005012	D-loop; other site
1151116005013	H-loop/switch region; other site
1151116005014	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
1151116005015	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1151116005016	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005017	dimer interface [polypeptide binding]; other site
1151116005018	conserved gate region; other site
1151116005019	ABC-ATPase subunit interface; other site
1151116005020	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116005021	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005022	dimer interface [polypeptide binding]; other site
1151116005023	conserved gate region; other site
1151116005024	putative PBP binding loops; other site
1151116005025	ABC-ATPase subunit interface; other site
1151116005026	Arabinogalactan endo-1,4-beta-galactosidase [Carbohydrate transport and metabolism]; Region: COG3867
1151116005027	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1151116005028	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1151116005029	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1151116005030	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1151116005031	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116005032	active site turn [active]
1151116005033	phosphorylation site [posttranslational modification]
1151116005034	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1151116005035	trimer interface; other site
1151116005036	sugar binding site [chemical binding]; other site
1151116005037	lac repressor; Reviewed; Region: lacI; PRK09526
1151116005038	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116005039	DNA binding site [nucleotide binding]
1151116005040	domain linker motif; other site
1151116005041	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1151116005042	ligand binding site [chemical binding]; other site
1151116005043	dimerization interface (open form) [polypeptide binding]; other site
1151116005044	dimerization interface (closed form) [polypeptide binding]; other site
1151116005045	Protein of unknown function (DUF805); Region: DUF805; pfam05656
1151116005046	Serine hydrolase; Region: Ser_hydrolase; pfam06821
1151116005047	ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768
1151116005048	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; pfam03802
1151116005049	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1151116005050	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1151116005051	citrate lyase subunit gamma; Provisional; Region: PRK13253
1151116005052	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1151116005053	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1151116005054	putative active site [active]
1151116005055	(T/H)XGH motif; other site
1151116005056	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303
1151116005057	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1151116005058	2-hydroxycarboxylate transporter family; Region: 2HCT; pfam03390
1151116005059	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1151116005060	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116005061	putative active site [active]
1151116005062	heme pocket [chemical binding]; other site
1151116005063	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116005064	ATP binding site [chemical binding]; other site
1151116005065	Mg2+ binding site [ion binding]; other site
1151116005066	G-X-G motif; other site
1151116005067	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1151116005068	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116005069	active site
1151116005070	phosphorylation site [posttranslational modification]
1151116005071	intermolecular recognition site; other site
1151116005072	dimerization interface [polypeptide binding]; other site
1151116005073	Transcriptional regulator; Region: CitT; pfam12431
1151116005074	MATE family multidrug exporter; Provisional; Region: PRK10189
1151116005075	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1151116005076	AMP nucleosidase; Provisional; Region: PRK08292
1151116005077	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1151116005078	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1151116005079	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1151116005080	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1151116005081	putative C-terminal domain interface [polypeptide binding]; other site
1151116005082	putative GSH binding site (G-site) [chemical binding]; other site
1151116005083	putative dimer interface [polypeptide binding]; other site
1151116005084	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1151116005085	putative N-terminal domain interface [polypeptide binding]; other site
1151116005086	putative dimer interface [polypeptide binding]; other site
1151116005087	putative substrate binding pocket (H-site) [chemical binding]; other site
1151116005088	shikimate transporter; Provisional; Region: PRK09952
1151116005089	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116005090	putative substrate translocation pore; other site
1151116005091	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1151116005092	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1151116005093	active site
1151116005094	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116005095	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005096	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1151116005097	putative effector binding pocket; other site
1151116005098	putative dimerization interface [polypeptide binding]; other site
1151116005099	short chain dehydrogenase; Provisional; Region: PRK12744
1151116005100	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116005101	NAD(P) binding site [chemical binding]; other site
1151116005102	active site
1151116005103	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116005104	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116005105	DNA binding site [nucleotide binding]
1151116005106	domain linker motif; other site
1151116005107	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
1151116005108	putative dimerization interface [polypeptide binding]; other site
1151116005109	putative ligand binding site [chemical binding]; other site
1151116005110	galactoside permease; Reviewed; Region: lacY; PRK09528
1151116005111	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116005112	putative substrate translocation pore; other site
1151116005113	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
1151116005114	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1151116005115	substrate binding [chemical binding]; other site
1151116005116	active site
1151116005117	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1151116005118	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1151116005119	MltA-interacting protein MipA; Region: MipA; cl01504
1151116005120	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1151116005121	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116005122	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1151116005123	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1151116005124	Glycosyl hydrolase family 68, includes levansucrase, beta-fructofuranosidase and inulosucrase; Region: GH68; cd08997
1151116005125	active site
1151116005126	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116005127	putative substrate translocation pore; other site
1151116005128	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116005129	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005130	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1151116005131	dimerization interface [polypeptide binding]; other site
1151116005132	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116005133	Coenzyme A binding pocket [chemical binding]; other site
1151116005134	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116005135	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005136	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1151116005137	putative effector binding pocket; other site
1151116005138	putative dimerization interface [polypeptide binding]; other site
1151116005139	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1151116005140	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116005141	putative substrate translocation pore; other site
1151116005142	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1151116005143	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1151116005144	Uncharacterized conserved protein [Function unknown]; Region: COG4925
1151116005145	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116005146	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005147	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116005148	putative effector binding pocket; other site
1151116005149	dimerization interface [polypeptide binding]; other site
1151116005150	progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs; Region: 5beta-POR_like_SDR_a; cd08948
1151116005151	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1151116005152	NAD(P) binding site [chemical binding]; other site
1151116005153	active site
1151116005154	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
1151116005155	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1151116005156	MarR family; Region: MarR; pfam01047
1151116005157	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1151116005158	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1151116005159	putative NAD(P) binding site [chemical binding]; other site
1151116005160	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116005161	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005162	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116005163	dimerization interface [polypeptide binding]; other site
1151116005164	Flavodoxin-like fold; Region: Flavodoxin_2; pfam02525
1151116005165	YCII-related domain; Region: YCII; cl00999
1151116005166	Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion]; Region: Tas; COG0667
1151116005167	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1151116005168	PPOX class probable FMN-dependent enzyme, DR_2398 family; Region: PPOX_FMN_DR2398; TIGR04025
1151116005169	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1151116005170	Chorismate mutase type II; Region: CM_2; smart00830
1151116005171	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1151116005172	Thymidylate kinase; Region: Thymidylate_kin; pfam02223
1151116005173	TMP-binding site; other site
1151116005174	ATP-binding site [chemical binding]; other site
1151116005175	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1151116005176	catalytic residues [active]
1151116005177	dimer interface [polypeptide binding]; other site
1151116005178	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1151116005179	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1151116005180	Walker A/P-loop; other site
1151116005181	ATP binding site [chemical binding]; other site
1151116005182	Q-loop/lid; other site
1151116005183	ABC transporter signature motif; other site
1151116005184	Walker B; other site
1151116005185	D-loop; other site
1151116005186	H-loop/switch region; other site
1151116005187	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1151116005188	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005189	dimer interface [polypeptide binding]; other site
1151116005190	conserved gate region; other site
1151116005191	putative PBP binding loops; other site
1151116005192	ABC-ATPase subunit interface; other site
1151116005193	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005194	dimer interface [polypeptide binding]; other site
1151116005195	conserved gate region; other site
1151116005196	putative PBP binding loops; other site
1151116005197	ABC-ATPase subunit interface; other site
1151116005198	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1151116005199	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1151116005200	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116005201	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116005202	metal binding site [ion binding]; metal-binding site
1151116005203	active site
1151116005204	I-site; other site
1151116005205	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1151116005206	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116005207	non-specific DNA binding site [nucleotide binding]; other site
1151116005208	salt bridge; other site
1151116005209	sequence-specific DNA binding site [nucleotide binding]; other site
1151116005210	Cupin domain; Region: Cupin_2; pfam07883
1151116005211	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1151116005212	B3/4 domain; Region: B3_4; pfam03483
1151116005213	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116005214	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116005215	DNA-binding site [nucleotide binding]; DNA binding site
1151116005216	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1151116005217	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116005218	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116005219	Walker A/P-loop; other site
1151116005220	ATP binding site [chemical binding]; other site
1151116005221	Q-loop/lid; other site
1151116005222	ABC transporter signature motif; other site
1151116005223	Walker B; other site
1151116005224	D-loop; other site
1151116005225	H-loop/switch region; other site
1151116005226	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116005227	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116005228	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005229	dimer interface [polypeptide binding]; other site
1151116005230	conserved gate region; other site
1151116005231	putative PBP binding loops; other site
1151116005232	ABC-ATPase subunit interface; other site
1151116005233	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116005234	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116005235	Walker A/P-loop; other site
1151116005236	ATP binding site [chemical binding]; other site
1151116005237	Q-loop/lid; other site
1151116005238	ABC transporter signature motif; other site
1151116005239	Walker B; other site
1151116005240	D-loop; other site
1151116005241	H-loop/switch region; other site
1151116005242	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116005243	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116005244	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005245	dimer interface [polypeptide binding]; other site
1151116005246	conserved gate region; other site
1151116005247	putative PBP binding loops; other site
1151116005248	ABC-ATPase subunit interface; other site
1151116005249	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116005250	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1151116005251	peptide binding site [polypeptide binding]; other site
1151116005252	Family of unknown function (DUF1028); Region: DUF1028; pfam06267
1151116005253	aspartate aminotransferase; Provisional; Region: PRK05764
1151116005254	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116005255	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116005256	homodimer interface [polypeptide binding]; other site
1151116005257	catalytic residue [active]
1151116005258	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1151116005259	conserved cys residue [active]
1151116005260	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1151116005261	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1151116005262	inhibitor site; inhibition site
1151116005263	active site
1151116005264	dimer interface [polypeptide binding]; other site
1151116005265	catalytic residue [active]
1151116005266	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1151116005267	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1151116005268	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1151116005269	active site
1151116005270	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1151116005271	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1151116005272	metal binding site [ion binding]; metal-binding site
1151116005273	substrate binding pocket [chemical binding]; other site
1151116005274	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
1151116005275	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1151116005276	metal binding site [ion binding]; metal-binding site
1151116005277	dimer interface [polypeptide binding]; other site
1151116005278	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116005279	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116005280	Walker A/P-loop; other site
1151116005281	ATP binding site [chemical binding]; other site
1151116005282	Q-loop/lid; other site
1151116005283	ABC transporter signature motif; other site
1151116005284	Walker B; other site
1151116005285	D-loop; other site
1151116005286	H-loop/switch region; other site
1151116005287	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116005288	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005289	dimer interface [polypeptide binding]; other site
1151116005290	conserved gate region; other site
1151116005291	putative PBP binding loops; other site
1151116005292	ABC-ATPase subunit interface; other site
1151116005293	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116005294	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116005295	substrate binding pocket [chemical binding]; other site
1151116005296	membrane-bound complex binding site; other site
1151116005297	hinge residues; other site
1151116005298	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1151116005299	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116005300	DNA-binding site [nucleotide binding]; DNA binding site
1151116005301	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116005302	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1151116005303	DNA-binding site [nucleotide binding]; DNA binding site
1151116005304	FCD domain; Region: FCD; pfam07729
1151116005305	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116005306	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1151116005307	NAD(P) binding site [chemical binding]; other site
1151116005308	active site
1151116005309	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1151116005310	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005311	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1151116005312	putative dimerization interface [polypeptide binding]; other site
1151116005313	Uncharacterized small protein [Function unknown]; Region: COG2879
1151116005314	carbon starvation protein A; Provisional; Region: PRK15015
1151116005315	Carbon starvation protein CstA; Region: CstA; pfam02554
1151116005316	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1151116005317	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1151116005318	dimer interface [polypeptide binding]; other site
1151116005319	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1151116005320	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116005321	DNA-binding site [nucleotide binding]; DNA binding site
1151116005322	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116005323	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116005324	homodimer interface [polypeptide binding]; other site
1151116005325	catalytic residue [active]
1151116005326	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1151116005327	putative active site [active]
1151116005328	Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069
1151116005329	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
1151116005330	N- and C-terminal domain interface [polypeptide binding]; other site
1151116005331	active site
1151116005332	MgATP binding site [chemical binding]; other site
1151116005333	catalytic site [active]
1151116005334	metal binding site [ion binding]; metal-binding site
1151116005335	carbohydrate binding site [chemical binding]; other site
1151116005336	putative homodimer interface [polypeptide binding]; other site
1151116005337	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116005338	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116005339	TM-ABC transporter signature motif; other site
1151116005340	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116005341	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116005342	TM-ABC transporter signature motif; other site
1151116005343	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1151116005344	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116005345	Walker A/P-loop; other site
1151116005346	ATP binding site [chemical binding]; other site
1151116005347	Q-loop/lid; other site
1151116005348	ABC transporter signature motif; other site
1151116005349	Walker B; other site
1151116005350	D-loop; other site
1151116005351	H-loop/switch region; other site
1151116005352	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116005353	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1151116005354	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1151116005355	ligand binding site [chemical binding]; other site
1151116005356	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1151116005357	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1151116005358	inhibitor-cofactor binding pocket; inhibition site
1151116005359	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116005360	catalytic residue [active]
1151116005361	Arginine N-succinyltransferase beta subunit; Region: AstA; cl11440
1151116005362	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
1151116005363	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1151116005364	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1151116005365	NAD(P) binding site [chemical binding]; other site
1151116005366	catalytic residues [active]
1151116005367	succinylarginine dihydrolase; Provisional; Region: PRK13281
1151116005368	succinylglutamate desuccinylase; Provisional; Region: PRK05324
1151116005369	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1151116005370	active site
1151116005371	Zn binding site [ion binding]; other site
1151116005372	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1151116005373	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116005374	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116005375	putative substrate translocation pore; other site
1151116005376	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1151116005377	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1151116005378	putative ligand binding site [chemical binding]; other site
1151116005379	NAD binding site [chemical binding]; other site
1151116005380	dimerization interface [polypeptide binding]; other site
1151116005381	catalytic site [active]
1151116005382	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1151116005383	DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481
1151116005384	active site
1151116005385	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1151116005386	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1151116005387	catalytic residues [active]
1151116005388	catalytic nucleophile [active]
1151116005389	Recombinase; Region: Recombinase; pfam07508
1151116005390	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1151116005391	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116005392	Walker A/P-loop; other site
1151116005393	ATP binding site [chemical binding]; other site
1151116005394	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1151116005395	ABC transporter signature motif; other site
1151116005396	Walker B; other site
1151116005397	D-loop; other site
1151116005398	H-loop/switch region; other site
1151116005399	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1151116005400	Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient...; Region: SR_Res_par; cd03767
1151116005401	catalytic residues [active]
1151116005402	catalytic nucleophile [active]
1151116005403	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1151116005404	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1151116005405	lipoprotein; Provisional; Region: PRK10598
1151116005406	glutaredoxin 2; Provisional; Region: PRK10387
1151116005407	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1151116005408	C-terminal domain interface [polypeptide binding]; other site
1151116005409	GSH binding site (G-site) [chemical binding]; other site
1151116005410	catalytic residues [active]
1151116005411	putative dimer interface [polypeptide binding]; other site
1151116005412	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1151116005413	N-terminal domain interface [polypeptide binding]; other site
1151116005414	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1151116005415	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116005416	putative substrate translocation pore; other site
1151116005417	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1151116005418	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1151116005419	hypothetical protein; Provisional; Region: PRK11239
1151116005420	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1151116005421	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1151116005422	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1151116005423	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1151116005424	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1151116005425	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1151116005426	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1151116005427	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1151116005428	active site
1151116005429	HIGH motif; other site
1151116005430	KMSK motif region; other site
1151116005431	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1151116005432	tRNA binding surface [nucleotide binding]; other site
1151116005433	anticodon binding site; other site
1151116005434	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1151116005435	putative metal binding site [ion binding]; other site
1151116005436	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
1151116005437	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116005438	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116005439	homodimer interface [polypeptide binding]; other site
1151116005440	catalytic residue [active]
1151116005441	copper homeostasis protein CutC; Provisional; Region: PRK11572
1151116005442	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116005443	S-adenosylmethionine binding site [chemical binding]; other site
1151116005444	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116005445	S-adenosylmethionine binding site [chemical binding]; other site
1151116005446	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1151116005447	Protein of unknown function DUF72; Region: DUF72; cl00777
1151116005448	Isochorismatase family; Region: Isochorismatase; pfam00857
1151116005449	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1151116005450	catalytic triad [active]
1151116005451	conserved cis-peptide bond; other site
1151116005452	potential frameshift: common BLAST hit: gi|322832431|ref|YP_004212458.1| aspartyl-tRNA synthetase
1151116005453	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1151116005454	nudix motif; other site
1151116005455	hypothetical protein; Validated; Region: PRK00110
1151116005456	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1151116005457	active site
1151116005458	putative DNA-binding cleft [nucleotide binding]; other site
1151116005459	dimer interface [polypeptide binding]; other site
1151116005460	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1151116005461	RuvA N terminal domain; Region: RuvA_N; pfam01330
1151116005462	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1151116005463	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1151116005464	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116005465	Walker A motif; other site
1151116005466	ATP binding site [chemical binding]; other site
1151116005467	Walker B motif; other site
1151116005468	arginine finger; other site
1151116005469	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1151116005470	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1151116005471	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1151116005472	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1151116005473	putative symporter YagG; Provisional; Region: PRK09669
1151116005474	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1151116005475	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116005476	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005477	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1151116005478	putative effector binding pocket; other site
1151116005479	putative dimerization interface [polypeptide binding]; other site
1151116005480	short chain dehydrogenase; Provisional; Region: PRK06172
1151116005481	classical (c) SDRs; Region: SDR_c; cd05233
1151116005482	NAD(P) binding site [chemical binding]; other site
1151116005483	active site
1151116005484	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
1151116005485	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116005486	active site turn [active]
1151116005487	phosphorylation site [posttranslational modification]
1151116005488	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116005489	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1151116005490	HPr interaction site; other site
1151116005491	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1151116005492	active site
1151116005493	phosphorylation site [posttranslational modification]
1151116005494	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1151116005495	beta-galactosidase; Region: BGL; TIGR03356
1151116005496	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1151116005497	CAT RNA binding domain; Region: CAT_RBD; smart01061
1151116005498	PRD domain; Region: PRD; pfam00874
1151116005499	PRD domain; Region: PRD; pfam00874
1151116005500	L-asparagine permease; Provisional; Region: PRK15049
1151116005501	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1151116005502	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1151116005503	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1151116005504	classical (c) SDRs; Region: SDR_c; cd05233
1151116005505	NAD(P) binding site [chemical binding]; other site
1151116005506	active site
1151116005507	Predicted transcriptional regulators [Transcription]; Region: COG1733
1151116005508	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1151116005509	X-Pro dipeptidyl-peptidase (S15 family); Region: Peptidase_S15; pfam02129
1151116005510	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1151116005511	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
1151116005512	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1151116005513	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116005514	Walker A/P-loop; other site
1151116005515	ATP binding site [chemical binding]; other site
1151116005516	Q-loop/lid; other site
1151116005517	ABC transporter signature motif; other site
1151116005518	Walker B; other site
1151116005519	D-loop; other site
1151116005520	H-loop/switch region; other site
1151116005521	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116005522	Walker A/P-loop; other site
1151116005523	ATP binding site [chemical binding]; other site
1151116005524	Q-loop/lid; other site
1151116005525	ABC transporter signature motif; other site
1151116005526	Walker B; other site
1151116005527	D-loop; other site
1151116005528	H-loop/switch region; other site
1151116005529	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116005530	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116005531	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005532	dimer interface [polypeptide binding]; other site
1151116005533	conserved gate region; other site
1151116005534	putative PBP binding loops; other site
1151116005535	ABC-ATPase subunit interface; other site
1151116005536	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116005537	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005538	dimer interface [polypeptide binding]; other site
1151116005539	conserved gate region; other site
1151116005540	ABC-ATPase subunit interface; other site
1151116005541	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116005542	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_17; cd08503
1151116005543	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1151116005544	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005545	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116005546	dimerization interface [polypeptide binding]; other site
1151116005547	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1151116005548	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116005549	DNA-binding site [nucleotide binding]; DNA binding site
1151116005550	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116005551	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116005552	homodimer interface [polypeptide binding]; other site
1151116005553	catalytic residue [active]
1151116005554	Domain of unknown function (DUF1127); Region: DUF1127; pfam06568
1151116005555	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1151116005556	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1151116005557	active site
1151116005558	HIGH motif; other site
1151116005559	KMSKS motif; other site
1151116005560	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1151116005561	tRNA binding surface [nucleotide binding]; other site
1151116005562	anticodon binding site; other site
1151116005563	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1151116005564	dimer interface [polypeptide binding]; other site
1151116005565	putative tRNA-binding site [nucleotide binding]; other site
1151116005566	antiporter inner membrane protein; Provisional; Region: PRK11670
1151116005567	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1151116005568	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1151116005569	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1151116005570	ATP-binding site [chemical binding]; other site
1151116005571	Sugar specificity; other site
1151116005572	Pyrimidine base specificity; other site
1151116005573	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1151116005574	trimer interface [polypeptide binding]; other site
1151116005575	active site
1151116005576	putative assembly protein; Provisional; Region: PRK10833
1151116005577	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1151116005578	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1151116005579	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1151116005580	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1151116005581	Transporter associated domain; Region: CorC_HlyC; smart01091
1151116005582	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1151116005583	active site
1151116005584	tetramer interface; other site
1151116005585	GtrA-like protein; Region: GtrA; pfam04138
1151116005586	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1151116005587	Ligand binding site; other site
1151116005588	Putative Catalytic site; other site
1151116005589	DXD motif; other site
1151116005590	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1151116005591	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1151116005592	substrate binding site; other site
1151116005593	tetramer interface; other site
1151116005594	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1151116005595	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1151116005596	NAD binding site [chemical binding]; other site
1151116005597	substrate binding site [chemical binding]; other site
1151116005598	homodimer interface [polypeptide binding]; other site
1151116005599	active site
1151116005600	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
1151116005601	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
1151116005602	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1151116005603	NADP binding site [chemical binding]; other site
1151116005604	active site
1151116005605	putative substrate binding site [chemical binding]; other site
1151116005606	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1151116005607	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1151116005608	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1151116005609	Walker A/P-loop; other site
1151116005610	ATP binding site [chemical binding]; other site
1151116005611	Q-loop/lid; other site
1151116005612	ABC transporter signature motif; other site
1151116005613	Walker B; other site
1151116005614	D-loop; other site
1151116005615	H-loop/switch region; other site
1151116005616	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
1151116005617	putative carbohydrate binding site [chemical binding]; other site
1151116005618	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1151116005619	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116005620	S-adenosylmethionine binding site [chemical binding]; other site
1151116005621	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1151116005622	Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; Region: GT2_RfbC_Mx_like; cd04184
1151116005623	Probable Catalytic site; other site
1151116005624	metal-binding site
1151116005625	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1151116005626	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1151116005627	Probable Catalytic site; other site
1151116005628	metal-binding site
1151116005629	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1151116005630	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
1151116005631	Probable Catalytic site; other site
1151116005632	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1151116005633	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1151116005634	Probable Catalytic site; other site
1151116005635	metal-binding site
1151116005636	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1151116005637	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1151116005638	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1151116005639	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1151116005640	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1151116005641	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1151116005642	metal binding site [ion binding]; metal-binding site
1151116005643	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1151116005644	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1151116005645	substrate binding site [chemical binding]; other site
1151116005646	glutamase interaction surface [polypeptide binding]; other site
1151116005647	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1151116005648	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1151116005649	catalytic residues [active]
1151116005650	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1151116005651	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1151116005652	putative active site [active]
1151116005653	oxyanion strand; other site
1151116005654	catalytic triad [active]
1151116005655	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1151116005656	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116005657	active site
1151116005658	motif I; other site
1151116005659	motif II; other site
1151116005660	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1151116005661	putative active site pocket [active]
1151116005662	4-fold oligomerization interface [polypeptide binding]; other site
1151116005663	metal binding residues [ion binding]; metal-binding site
1151116005664	3-fold/trimer interface [polypeptide binding]; other site
1151116005665	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1151116005666	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116005667	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116005668	homodimer interface [polypeptide binding]; other site
1151116005669	catalytic residue [active]
1151116005670	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1151116005671	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1151116005672	NAD binding site [chemical binding]; other site
1151116005673	dimerization interface [polypeptide binding]; other site
1151116005674	product binding site; other site
1151116005675	substrate binding site [chemical binding]; other site
1151116005676	zinc binding site [ion binding]; other site
1151116005677	catalytic residues [active]
1151116005678	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1151116005679	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1151116005680	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1151116005681	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1151116005682	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1151116005683	putative NAD(P) binding site [chemical binding]; other site
1151116005684	transcriptional activator FlhD; Provisional; Region: PRK02909
1151116005685	transcriptional activator FlhC; Provisional; Region: PRK12722
1151116005686	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1151116005687	flagellar motor protein MotA; Validated; Region: PRK09110
1151116005688	flagellar motor protein MotB; Validated; Region: motB; PRK09041
1151116005689	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1151116005690	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1151116005691	ligand binding site [chemical binding]; other site
1151116005692	chemotaxis protein CheA; Provisional; Region: PRK10547
1151116005693	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1151116005694	putative binding surface; other site
1151116005695	active site
1151116005696	CheY binding; Region: CheY-binding; pfam09078
1151116005697	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1151116005698	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116005699	ATP binding site [chemical binding]; other site
1151116005700	Mg2+ binding site [ion binding]; other site
1151116005701	G-X-G motif; other site
1151116005702	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1151116005703	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1151116005704	putative CheA interaction surface; other site
1151116005705	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1151116005706	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1151116005707	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1151116005708	dimer interface [polypeptide binding]; other site
1151116005709	active site
1151116005710	Int/Topo IB signature motif; other site
1151116005711	Excisionase-like protein; Region: Exc; pfam07825
1151116005712	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
1151116005713	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116005714	non-specific DNA binding site [nucleotide binding]; other site
1151116005715	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1151116005716	salt bridge; other site
1151116005717	sequence-specific DNA binding site [nucleotide binding]; other site
1151116005718	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1151116005719	Catalytic site [active]
1151116005720	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
1151116005721	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1151116005722	Helix-turn-helix domain; Region: HTH_36; pfam13730
1151116005723	Conserved phage C-terminus (Phg_2220_C); Region: Phg_2220_C; pfam09524
1151116005724	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
1151116005725	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
1151116005726	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
1151116005727	Phage antirepressor protein KilAC domain; Region: ANT; cl01462
1151116005728	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1151116005729	active site
1151116005730	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1151116005731	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1151116005732	Bacillus subtilis YydB and related proteins, metallophosphatase domain; Region: MPP_YydB; cd07400
1151116005733	putative active site [active]
1151116005734	putative metal binding site [ion binding]; other site
1151116005735	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1151116005736	Protein of unknown function (DUF754); Region: DUF754; pfam05449
1151116005737	Predicted chitinase [General function prediction only]; Region: COG3179
1151116005738	catalytic residue [active]
1151116005739	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1151116005740	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1151116005741	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1151116005742	potential frameshift: common BLAST hit: gi|322835205|ref|YP_004215231.1| phage portal protein, lambda family
1151116005743	Clp protease; Region: CLP_protease; pfam00574
1151116005744	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1151116005745	oligomer interface [polypeptide binding]; other site
1151116005746	active site residues [active]
1151116005747	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
1151116005748	Uncharacterized conserved protein (DUF2190); Region: DUF2190; cl02289
1151116005749	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
1151116005750	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1151116005751	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1151116005752	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1151116005753	Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629
1151116005754	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; cl06106
1151116005755	Minor tail protein T; Region: Phage_tail_T; cl05636
1151116005756	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1151116005757	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
1151116005758	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1151116005759	Phage minor tail protein; Region: Phage_min_tail; cl01940
1151116005760	Phage minor tail protein L; Region: Phage_tail_L; cl01908
1151116005761	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1151116005762	MPN+ (JAMM) motif; other site
1151116005763	Zinc-binding site [ion binding]; other site
1151116005764	NlpC/P60 family; Region: NLPC_P60; cl17555
1151116005765	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1151116005766	Phage-related protein, tail component [Function unknown]; Region: COG4723
1151116005767	Phage-related protein, tail component [Function unknown]; Region: COG4733
1151116005768	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1151116005769	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1151116005770	Interdomain contacts; other site
1151116005771	Cytokine receptor motif; other site
1151116005772	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1151116005773	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1151116005774	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1151116005775	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1151116005776	Catalytic site [active]
1151116005777	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1151116005778	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1151116005779	active site
1151116005780	DNA binding site [nucleotide binding]
1151116005781	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1151116005782	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
1151116005783	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
1151116005784	RES domain; Region: RES; pfam08808
1151116005785	Helix-turn-helix domain; Region: HTH_19; pfam12844
1151116005786	non-specific DNA binding site [nucleotide binding]; other site
1151116005787	salt bridge; other site
1151116005788	sequence-specific DNA binding site [nucleotide binding]; other site
1151116005789	transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393
1151116005790	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1151116005791	conserved cys residue [active]
1151116005792	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116005793	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116005794	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116005795	putative substrate translocation pore; other site
1151116005796	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1151116005797	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1151116005798	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1151116005799	dimer interface [polypeptide binding]; other site
1151116005800	ligand binding site [chemical binding]; other site
1151116005801	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116005802	dimerization interface [polypeptide binding]; other site
1151116005803	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116005804	dimer interface [polypeptide binding]; other site
1151116005805	putative CheW interface [polypeptide binding]; other site
1151116005806	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1151116005807	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1151116005808	dimer interface [polypeptide binding]; other site
1151116005809	ligand binding site [chemical binding]; other site
1151116005810	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1151116005811	dimerization interface [polypeptide binding]; other site
1151116005812	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116005813	dimer interface [polypeptide binding]; other site
1151116005814	putative CheW interface [polypeptide binding]; other site
1151116005815	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1151116005816	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1151116005817	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116005818	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1151116005819	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116005820	active site
1151116005821	phosphorylation site [posttranslational modification]
1151116005822	intermolecular recognition site; other site
1151116005823	dimerization interface [polypeptide binding]; other site
1151116005824	CheB methylesterase; Region: CheB_methylest; pfam01339
1151116005825	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1151116005826	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116005827	active site
1151116005828	phosphorylation site [posttranslational modification]
1151116005829	intermolecular recognition site; other site
1151116005830	dimerization interface [polypeptide binding]; other site
1151116005831	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1151116005832	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK12468
1151116005833	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1151116005834	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1151116005835	FHIPEP family; Region: FHIPEP; pfam00771
1151116005836	Flagellar protein FlhE; Region: FlhE; pfam06366
1151116005837	PAAR motif; Region: PAAR_motif; pfam05488
1151116005838	FlgN protein; Region: FlgN; cl09176
1151116005839	Anti-sigma-28 factor, FlgM; Region: FlgM; cl01052
1151116005840	SAF-like; Region: SAF_2; pfam13144
1151116005841	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1151116005842	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1151116005843	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1151116005844	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1151116005845	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1151116005846	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1151116005847	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1151116005848	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
1151116005849	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1151116005850	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1151116005851	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1151116005852	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1151116005853	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1151116005854	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1151116005855	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
1151116005856	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1151116005857	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1151116005858	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1151116005859	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1151116005860	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1151116005861	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1151116005862	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1151116005863	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1151116005864	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1151116005865	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1151116005866	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1151116005867	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1151116005868	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1151116005869	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1151116005870	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1151116005871	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1151116005872	hypothetical protein; Provisional; Region: PRK10711
1151116005873	hypothetical protein; Provisional; Region: PRK01821
1151116005874	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116005875	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116005876	Walker A/P-loop; other site
1151116005877	ATP binding site [chemical binding]; other site
1151116005878	Q-loop/lid; other site
1151116005879	ABC transporter signature motif; other site
1151116005880	Walker B; other site
1151116005881	D-loop; other site
1151116005882	H-loop/switch region; other site
1151116005883	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005884	dimer interface [polypeptide binding]; other site
1151116005885	conserved gate region; other site
1151116005886	putative PBP binding loops; other site
1151116005887	ABC-ATPase subunit interface; other site
1151116005888	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1151116005889	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116005890	Coenzyme A binding pocket [chemical binding]; other site
1151116005891	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116005892	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116005893	substrate binding pocket [chemical binding]; other site
1151116005894	membrane-bound complex binding site; other site
1151116005895	hinge residues; other site
1151116005896	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1151116005897	M20 Peptidase Aminoacyclase-1 YxeP-like proteins, including YxeP, YtnL, YjiB and HipO2; Region: M20_Acy1_YxeP_like; cd05669
1151116005898	metal binding site [ion binding]; metal-binding site
1151116005899	dimer interface [polypeptide binding]; other site
1151116005900	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1151116005901	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1151116005902	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1151116005903	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1151116005904	active site
1151116005905	non-prolyl cis peptide bond; other site
1151116005906	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116005907	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116005908	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1151116005909	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1151116005910	NADP binding site [chemical binding]; other site
1151116005911	dimer interface [polypeptide binding]; other site
1151116005912	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1151116005913	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1151116005914	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116005915	active site
1151116005916	phosphorylation site [posttranslational modification]
1151116005917	intermolecular recognition site; other site
1151116005918	dimerization interface [polypeptide binding]; other site
1151116005919	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
1151116005920	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1151116005921	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1151116005922	active site
1151116005923	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1151116005924	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1151116005925	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116005926	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005927	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116005928	dimerization interface [polypeptide binding]; other site
1151116005929	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1151116005930	HTH-like domain; Region: HTH_21; pfam13276
1151116005931	Integrase core domain; Region: rve; pfam00665
1151116005932	Integrase core domain; Region: rve_3; pfam13683
1151116005933	Transposase; Region: HTH_Tnp_1; pfam01527
1151116005934	potential frameshift: common BLAST hit: gi|322832591|ref|YP_004212618.1| 2-methylcitrate dehydratase
1151116005935	Phosphotransferase enzyme family; Region: APH; pfam01636
1151116005936	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116005937	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116005938	putative substrate translocation pore; other site
1151116005939	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1151116005940	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116005941	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116005942	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1151116005943	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1151116005944	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1151116005945	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1151116005946	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116005947	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1151116005948	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
1151116005949	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1151116005950	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1151116005951	heme binding site [chemical binding]; other site
1151116005952	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1151116005953	heme binding site [chemical binding]; other site
1151116005954	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1151116005955	FAD binding domain; Region: FAD_binding_4; pfam01565
1151116005956	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1151116005957	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116005958	dimer interface [polypeptide binding]; other site
1151116005959	conserved gate region; other site
1151116005960	putative PBP binding loops; other site
1151116005961	ABC-ATPase subunit interface; other site
1151116005962	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1151116005963	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1151116005964	Walker A/P-loop; other site
1151116005965	ATP binding site [chemical binding]; other site
1151116005966	Q-loop/lid; other site
1151116005967	ABC transporter signature motif; other site
1151116005968	Walker B; other site
1151116005969	D-loop; other site
1151116005970	H-loop/switch region; other site
1151116005971	NMT1/THI5 like; Region: NMT1; pfam09084
1151116005972	Creatinine amidohydrolase; Region: Creatininase; pfam02633
1151116005973	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1151116005974	homotrimer interaction site [polypeptide binding]; other site
1151116005975	putative active site [active]
1151116005976	cytosine deaminase-like protein; Validated; Region: PRK07583
1151116005977	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1151116005978	active site
1151116005979	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
1151116005980	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
1151116005981	FMN-binding pocket [chemical binding]; other site
1151116005982	flavin binding motif; other site
1151116005983	phosphate binding motif [ion binding]; other site
1151116005984	beta-alpha-beta structure motif; other site
1151116005985	NAD binding pocket [chemical binding]; other site
1151116005986	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1151116005987	catalytic loop [active]
1151116005988	iron binding site [ion binding]; other site
1151116005989	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116005990	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116005991	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116005992	dimerization interface [polypeptide binding]; other site
1151116005993	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1151116005994	amidohydrolase; Provisional; Region: PRK12393
1151116005995	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1151116005996	active site
1151116005997	putative substrate binding pocket [chemical binding]; other site
1151116005998	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
1151116005999	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
1151116006000	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
1151116006001	Putative motility protein; Region: YjfB_motility; pfam14070
1151116006002	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1151116006003	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116006004	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1151116006005	substrate binding site [chemical binding]; other site
1151116006006	ATP binding site [chemical binding]; other site
1151116006007	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1151116006008	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1151116006009	putative active site [active]
1151116006010	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1151116006011	dimer interface [polypeptide binding]; other site
1151116006012	active site
1151116006013	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1151116006014	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116006015	substrate binding pocket [chemical binding]; other site
1151116006016	membrane-bound complex binding site; other site
1151116006017	hinge residues; other site
1151116006018	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1151116006019	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116006020	DNA-binding site [nucleotide binding]; DNA binding site
1151116006021	UTRA domain; Region: UTRA; pfam07702
1151116006022	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116006023	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116006024	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1151116006025	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1151116006026	FMN binding site [chemical binding]; other site
1151116006027	active site
1151116006028	substrate binding site [chemical binding]; other site
1151116006029	catalytic residue [active]
1151116006030	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1151116006031	classical (c) SDRs; Region: SDR_c; cd05233
1151116006032	NAD(P) binding site [chemical binding]; other site
1151116006033	active site
1151116006034	short chain dehydrogenase; Provisional; Region: PRK06179
1151116006035	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1151116006036	NADP binding site [chemical binding]; other site
1151116006037	active site
1151116006038	steroid binding site; other site
1151116006039	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1151116006040	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1151116006041	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116006042	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116006043	YsiA-like protein, C-terminal region; Region: TetR_C_4; pfam08359
1151116006044	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1151116006045	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116006046	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116006047	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1151116006048	short chain dehydrogenase; Provisional; Region: PRK06500
1151116006049	classical (c) SDRs; Region: SDR_c; cd05233
1151116006050	NAD(P) binding site [chemical binding]; other site
1151116006051	active site
1151116006052	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
1151116006053	Domain of unknown function (DUF955); Region: DUF955; pfam06114
1151116006054	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1151116006055	Part of AAA domain; Region: AAA_19; pfam13245
1151116006056	Family description; Region: UvrD_C_2; pfam13538
1151116006057	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1151116006058	Bacterial multiubiquitin; Region: Bac_multiUb; pfam14452
1151116006059	Bacterial multiubiquitin; Region: Bac_multiUb; pfam14452
1151116006060	hypothetical protein; Provisional; Region: PRK06153
1151116006061	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
1151116006062	ATP binding site [chemical binding]; other site
1151116006063	substrate interface [chemical binding]; other site
1151116006064	Lhr-like helicases [General function prediction only]; Region: Lhr; COG1201
1151116006065	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116006066	ATP binding site [chemical binding]; other site
1151116006067	putative Mg++ binding site [ion binding]; other site
1151116006068	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116006069	nucleotide binding region [chemical binding]; other site
1151116006070	ATP-binding site [chemical binding]; other site
1151116006071	P-loop Domain of unknown function (DUF2791); Region: DUF2791; pfam10923
1151116006072	AAA ATPase domain; Region: AAA_16; pfam13191
1151116006073	Domain of unknown function (DUF4016); Region: DUF4016; pfam13208
1151116006074	tellurite resistance protein terB; Region: terB; cd07176
1151116006075	putative metal binding site [ion binding]; other site
1151116006076	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
1151116006077	Protein of unknown function, DUF462; Region: DUF462; cl01190
1151116006078	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1151116006079	HTH-like domain; Region: HTH_21; pfam13276
1151116006080	Integrase core domain; Region: rve; pfam00665
1151116006081	Integrase core domain; Region: rve_3; pfam13683
1151116006082	Transposase; Region: HTH_Tnp_1; pfam01527
1151116006083	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
1151116006084	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1151116006085	Ion channel; Region: Ion_trans_2; pfam07885
1151116006086	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1151116006087	active site
1151116006088	DNA binding site [nucleotide binding]
1151116006089	Int/Topo IB signature motif; other site
1151116006090	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116006091	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116006092	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116006093	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
1151116006094	Mg2+ binding site [ion binding]; other site
1151116006095	G-X-G motif; other site
1151116006096	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1151116006097	dGTP triphosphohydrolase [Nucleotide transport and metabolism]; Region: Dgt; COG0232
1151116006098	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1151116006099	Zn2+ binding site [ion binding]; other site
1151116006100	Mg2+ binding site [ion binding]; other site
1151116006101	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1151116006102	potential frameshift: common BLAST hit: gi|50120542|ref|YP_049709.1| mobilization protein
1151116006103	conjugal transfer protein TrbM; Provisional; Region: PRK13893
1151116006104	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
1151116006105	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1151116006106	Walker A motif; other site
1151116006107	hexamer interface [polypeptide binding]; other site
1151116006108	ATP binding site [chemical binding]; other site
1151116006109	Walker B motif; other site
1151116006110	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
1151116006111	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1151116006112	VirB7 interaction site; other site
1151116006113	VirB8 protein; Region: VirB8; pfam04335
1151116006114	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
1151116006115	P-type DNA transfer protein VirB5; Region: VirB5; TIGR02791
1151116006116	Type IV secretion system proteins; Region: T4SS; pfam07996
1151116006117	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
1151116006118	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1151116006119	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1151116006120	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
1151116006121	TrbC/VIRB2 family; Region: TrbC; cl01583
1151116006122	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116006123	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116006124	catalytic residue [active]
1151116006125	phage/conjugal plasmid C-4 type zinc finger protein, TraR family; Region: C4_traR_proteo; TIGR02419
1151116006126	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
1151116006127	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1151116006128	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1151116006129	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006130	putative substrate translocation pore; other site
1151116006131	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
1151116006132	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1151116006133	potential catalytic triad [active]
1151116006134	conserved cys residue [active]
1151116006135	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116006136	transcriptional activator TtdR; Provisional; Region: PRK09801
1151116006137	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116006138	putative effector binding pocket; other site
1151116006139	dimerization interface [polypeptide binding]; other site
1151116006140	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116006141	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116006142	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116006143	dimerization interface [polypeptide binding]; other site
1151116006144	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1151116006145	active site
1151116006146	catalytic site [active]
1151116006147	Zn binding site [ion binding]; other site
1151116006148	tetramer interface [polypeptide binding]; other site
1151116006149	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1151116006150	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1151116006151	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1151116006152	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1151116006153	proposed catalytic triad [active]
1151116006154	conserved cys residue [active]
1151116006155	Cupin domain; Region: Cupin_2; cl17218
1151116006156	ASCH domain; Region: ASCH; pfam04266
1151116006157	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1151116006158	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116006159	Coenzyme A binding pocket [chemical binding]; other site
1151116006160	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
1151116006161	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
1151116006162	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1151116006163	putative di-iron ligands [ion binding]; other site
1151116006164	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1151116006165	EamA-like transporter family; Region: EamA; pfam00892
1151116006166	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1151116006167	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
1151116006168	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1151116006169	inhibitor-cofactor binding pocket; inhibition site
1151116006170	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116006171	catalytic residue [active]
1151116006172	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1151116006173	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1151116006174	acyl-activating enzyme (AAE) consensus motif; other site
1151116006175	AMP binding site [chemical binding]; other site
1151116006176	active site
1151116006177	CoA binding site [chemical binding]; other site
1151116006178	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1151116006179	Phosphopantetheine attachment site; Region: PP-binding; cl09936
1151116006180	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292
1151116006181	active site
1151116006182	Condensation domain; Region: Condensation; pfam00668
1151116006183	HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745
1151116006184	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1151116006185	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1151116006186	acyl-activating enzyme (AAE) consensus motif; other site
1151116006187	AMP binding site [chemical binding]; other site
1151116006188	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1151116006189	Thioesterase domain; Region: Thioesterase; pfam00975
1151116006190	Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntD; COG2977
1151116006191	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1151116006192	short chain dehydrogenase; Provisional; Region: PRK08309
1151116006193	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1151116006194	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1151116006195	active site
1151116006196	Int/Topo IB signature motif; other site
1151116006197	Phosphoenolpyruvate:glucose-phosphotransferase regulator; Region: MtfA; cl01267
1151116006198	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1151116006199	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116006200	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
1151116006201	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1151116006202	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1151116006203	Protein of unknown function (DUF3450); Region: DUF3450; pfam11932
1151116006204	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
1151116006205	Family description; Region: VCBS; pfam13517
1151116006206	Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256
1151116006207	Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255
1151116006208	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1151116006209	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1151116006210	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1151116006211	amphipathic channel; other site
1151116006212	Asn-Pro-Ala signature motifs; other site
1151116006213	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1151116006214	Phenolic acid decarboxylase (PAD); Region: PA_decarbox; cl01382
1151116006215	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116006216	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116006217	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116006218	dimerization interface [polypeptide binding]; other site
1151116006219	putative metal dependent hydrolase; Provisional; Region: PRK11598
1151116006220	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1151116006221	Sulfatase; Region: Sulfatase; pfam00884
1151116006222	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1151116006223	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1151116006224	putative trimer interface [polypeptide binding]; other site
1151116006225	putative CoA binding site [chemical binding]; other site
1151116006226	Protein of unknown function (DUF2891); Region: DUF2891; pfam11199
1151116006227	Predicted membrane protein [Function unknown]; Region: COG3817
1151116006228	Protein of unknown function (DUF979); Region: DUF979; pfam06166
1151116006229	Protein of unknown function (DUF969); Region: DUF969; pfam06149
1151116006230	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
1151116006231	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1151116006232	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1151116006233	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1151116006234	putative NAD(P) binding site [chemical binding]; other site
1151116006235	putative substrate binding site [chemical binding]; other site
1151116006236	catalytic Zn binding site [ion binding]; other site
1151116006237	structural Zn binding site [ion binding]; other site
1151116006238	dimer interface [polypeptide binding]; other site
1151116006239	Ion transport protein; Region: Ion_trans; pfam00520
1151116006240	Ion channel; Region: Ion_trans_2; pfam07885
1151116006241	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1151116006242	DNA-binding site [nucleotide binding]; DNA binding site
1151116006243	RNA-binding motif; other site
1151116006244	hypothetical protein; Provisional; Region: PRK10708
1151116006245	Tar ligand binding domain homologue; Region: TarH; pfam02203
1151116006246	dimer interface [polypeptide binding]; other site
1151116006247	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116006248	dimerization interface [polypeptide binding]; other site
1151116006249	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116006250	dimer interface [polypeptide binding]; other site
1151116006251	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1151116006252	putative CheW interface [polypeptide binding]; other site
1151116006253	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1151116006254	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116006255	DNA binding residues [nucleotide binding]
1151116006256	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
1151116006257	galactoside permease; Reviewed; Region: lacY; PRK09528
1151116006258	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006259	putative substrate translocation pore; other site
1151116006260	Uncharacterized protein conserved in bacteria (DUF2264); Region: DUF2264; pfam10022
1151116006261	Cupin domain; Region: Cupin_2; pfam07883
1151116006262	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116006263	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116006264	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116006265	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
1151116006266	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1151116006267	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1151116006268	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1151116006269	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1151116006270	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1151116006271	dimer interface [polypeptide binding]; other site
1151116006272	active site
1151116006273	metal binding site [ion binding]; metal-binding site
1151116006274	Predicted membrane protein [Function unknown]; Region: COG2733
1151116006275	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116006276	dimerization interface [polypeptide binding]; other site
1151116006277	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116006278	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1151116006279	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1151116006280	Walker A/P-loop; other site
1151116006281	ATP binding site [chemical binding]; other site
1151116006282	Q-loop/lid; other site
1151116006283	ABC transporter signature motif; other site
1151116006284	Walker B; other site
1151116006285	D-loop; other site
1151116006286	H-loop/switch region; other site
1151116006287	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264
1151116006288	Protein of unknown function (DUF3772); Region: DUF3772; pfam12607
1151116006289	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1151116006290	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1151116006291	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1151116006292	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116006293	Outer membrane efflux protein; Region: OEP; pfam02321
1151116006294	Outer membrane efflux protein; Region: OEP; pfam02321
1151116006295	Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604
1151116006296	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1151116006297	Mycobacterium tuberculosis CorA-like subfamily; Region: MtCorA-like; cd12830
1151116006298	oligomer interface [polypeptide binding]; other site
1151116006299	metal binding site [ion binding]; metal-binding site
1151116006300	metal binding site [ion binding]; metal-binding site
1151116006301	putative Cl binding site [ion binding]; other site
1151116006302	basic sphincter; other site
1151116006303	hydrophobic gate; other site
1151116006304	periplasmic entrance; other site
1151116006305	short chain dehydrogenase; Provisional; Region: PRK06180
1151116006306	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1151116006307	NADP binding site [chemical binding]; other site
1151116006308	active site
1151116006309	steroid binding site; other site
1151116006310	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1151116006311	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1151116006312	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116006313	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1151116006314	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006315	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1151116006316	putative substrate translocation pore; other site
1151116006317	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006318	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1151116006319	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116006320	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116006321	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1151116006322	Cation efflux family; Region: Cation_efflux; cl00316
1151116006323	alkaline phosphatase; Provisional; Region: PRK10518
1151116006324	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1151116006325	dimer interface [polypeptide binding]; other site
1151116006326	active site
1151116006327	L,D-transpeptidase; Provisional; Region: PRK10260
1151116006328	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
1151116006329	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1151116006330	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1151116006331	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006332	putative substrate translocation pore; other site
1151116006333	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1151116006334	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116006335	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116006336	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116006337	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116006338	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1151116006339	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116006340	N-terminal plug; other site
1151116006341	ligand-binding site [chemical binding]; other site
1151116006342	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1151116006343	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116006344	S-adenosylmethionine binding site [chemical binding]; other site
1151116006345	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1151116006346	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1151116006347	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1151116006348	Chromate transporter; Region: Chromate_transp; pfam02417
1151116006349	Chromate transporter; Region: Chromate_transp; pfam02417
1151116006350	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116006351	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116006352	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1151116006353	putative dimerization interface [polypeptide binding]; other site
1151116006354	putative substrate binding pocket [chemical binding]; other site
1151116006355	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116006356	dimerization interface [polypeptide binding]; other site
1151116006357	putative DNA binding site [nucleotide binding]; other site
1151116006358	putative Zn2+ binding site [ion binding]; other site
1151116006359	elongation factor G; Reviewed; Region: PRK00007
1151116006360	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1151116006361	G1 box; other site
1151116006362	putative GEF interaction site [polypeptide binding]; other site
1151116006363	GTP/Mg2+ binding site [chemical binding]; other site
1151116006364	Switch I region; other site
1151116006365	G2 box; other site
1151116006366	G3 box; other site
1151116006367	Switch II region; other site
1151116006368	G4 box; other site
1151116006369	G5 box; other site
1151116006370	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1151116006371	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1151116006372	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1151116006373	Post-segregation antitoxin CcdA; Region: CcdA; cl02188
1151116006374	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1151116006375	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1151116006376	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1151116006377	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1151116006378	DNA binding site [nucleotide binding]
1151116006379	active site
1151116006380	Int/Topo IB signature motif; other site
1151116006381	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
1151116006382	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1151116006383	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1151116006384	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1151116006385	Periplasmic pectate lyase; Region: Pectate_lyase_2; pfam06917
1151116006386	YadA-like C-terminal region; Region: YadA; pfam03895
1151116006387	EthD domain; Region: EthD; cl17553
1151116006388	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1151116006389	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1151116006390	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1151116006391	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116006392	ABC-ATPase subunit  interface; other site
1151116006393	dimer interface [polypeptide binding]; other site
1151116006394	putative PBP binding regions; other site
1151116006395	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1151116006396	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1151116006397	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1151116006398	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1151116006399	metal binding site [ion binding]; metal-binding site
1151116006400	putative peptidase; Provisional; Region: PRK11649
1151116006401	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1151116006402	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1151116006403	Peptidase family M23; Region: Peptidase_M23; pfam01551
1151116006404	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1151116006405	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1151116006406	putative acyl-acceptor binding pocket; other site
1151116006407	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1151116006408	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006409	putative substrate translocation pore; other site
1151116006410	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1151116006411	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
1151116006412	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
1151116006413	IucA / IucC family; Region: IucA_IucC; pfam04183
1151116006414	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1151116006415	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
1151116006416	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1151116006417	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1151116006418	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116006419	catalytic residue [active]
1151116006420	pyruvate kinase; Provisional; Region: PRK05826
1151116006421	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1151116006422	domain interfaces; other site
1151116006423	active site
1151116006424	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1151116006425	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116006426	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1151116006427	putative active site [active]
1151116006428	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1151116006429	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1151116006430	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1151116006431	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1151116006432	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1151116006433	active site
1151116006434	intersubunit interface [polypeptide binding]; other site
1151116006435	catalytic residue [active]
1151116006436	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1151116006437	homotrimer interaction site [polypeptide binding]; other site
1151116006438	putative active site [active]
1151116006439	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1151116006440	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1151116006441	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1151116006442	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1151116006443	Glycoprotease family; Region: Peptidase_M22; pfam00814
1151116006444	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
1151116006445	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1151116006446	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1151116006447	acyl-activating enzyme (AAE) consensus motif; other site
1151116006448	putative AMP binding site [chemical binding]; other site
1151116006449	putative active site [active]
1151116006450	putative CoA binding site [chemical binding]; other site
1151116006451	ribonuclease D; Provisional; Region: PRK10829
1151116006452	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1151116006453	catalytic site [active]
1151116006454	putative active site [active]
1151116006455	putative substrate binding site [chemical binding]; other site
1151116006456	HRDC domain; Region: HRDC; pfam00570
1151116006457	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1151116006458	cell division inhibitor MinD; Provisional; Region: PRK10818
1151116006459	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1151116006460	Switch I; other site
1151116006461	Switch II; other site
1151116006462	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1151116006463	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1151116006464	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1151116006465	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1151116006466	lytic murein transglycosylase; Region: MltB_2; TIGR02283
1151116006467	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116006468	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116006469	hypothetical protein; Provisional; Region: PRK10691
1151116006470	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1151116006471	hypothetical protein; Provisional; Region: PRK05170
1151116006472	anti-RssB factor; Provisional; Region: PRK10244
1151116006473	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1151116006474	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1151116006475	disulfide bond formation protein B; Provisional; Region: PRK01749
1151116006476	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
1151116006477	fatty acid metabolism regulator; Provisional; Region: PRK04984
1151116006478	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116006479	DNA-binding site [nucleotide binding]; DNA binding site
1151116006480	FadR C-terminal domain; Region: FadR_C; pfam07840
1151116006481	SpoVR family protein; Provisional; Region: PRK11767
1151116006482	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1151116006483	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1151116006484	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1151116006485	YdfZ protein; Region: YdfZ; cl11878
1151116006486	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1151116006487	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1151116006488	alanine racemase; Reviewed; Region: dadX; PRK03646
1151116006489	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1151116006490	active site
1151116006491	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1151116006492	substrate binding site [chemical binding]; other site
1151116006493	catalytic residues [active]
1151116006494	dimer interface [polypeptide binding]; other site
1151116006495	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006496	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1151116006497	putative substrate translocation pore; other site
1151116006498	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1151116006499	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1151116006500	homodimer interface [polypeptide binding]; other site
1151116006501	NAD binding pocket [chemical binding]; other site
1151116006502	ATP binding pocket [chemical binding]; other site
1151116006503	Mg binding site [ion binding]; other site
1151116006504	active-site loop [active]
1151116006505	Protein of unknown function, DUF481; Region: DUF481; cl01213
1151116006506	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116006507	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116006508	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116006509	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1151116006510	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1151116006511	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1151116006512	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1151116006513	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116006514	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116006515	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116006516	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
1151116006517	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
1151116006518	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116006519	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116006520	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116006521	Disulfide bond isomerase protein N-terminus; Region: DsbC_N; pfam10411
1151116006522	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1151116006523	hypothetical protein; Provisional; Region: PRK05325
1151116006524	PrkA family serine protein kinase; Provisional; Region: PRK15455
1151116006525	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116006526	Walker A motif; other site
1151116006527	ATP binding site [chemical binding]; other site
1151116006528	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1151116006529	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1151116006530	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116006531	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116006532	active site
1151116006533	catalytic tetrad [active]
1151116006534	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1151116006535	active site
1151116006536	phosphate binding residues; other site
1151116006537	catalytic residues [active]
1151116006538	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1151116006539	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1151116006540	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1151116006541	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1151116006542	SelR domain; Region: SelR; pfam01641
1151116006543	Protein of unknown function (DUF1315); Region: DUF1315; pfam07023
1151116006544	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1151116006545	Isochorismatase family; Region: Isochorismatase; pfam00857
1151116006546	catalytic triad [active]
1151116006547	metal binding site [ion binding]; metal-binding site
1151116006548	conserved cis-peptide bond; other site
1151116006549	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1151116006550	active site
1151116006551	homodimer interface [polypeptide binding]; other site
1151116006552	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
1151116006553	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1151116006554	tandem repeat interface [polypeptide binding]; other site
1151116006555	oligomer interface [polypeptide binding]; other site
1151116006556	active site residues [active]
1151116006557	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
1151116006558	active site
1151116006559	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1151116006560	putative FMN binding site [chemical binding]; other site
1151116006561	DNA topoisomerase III; Provisional; Region: PRK07726
1151116006562	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1151116006563	active site
1151116006564	putative interdomain interaction site [polypeptide binding]; other site
1151116006565	putative metal-binding site [ion binding]; other site
1151116006566	putative nucleotide binding site [chemical binding]; other site
1151116006567	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1151116006568	domain I; other site
1151116006569	DNA binding groove [nucleotide binding]
1151116006570	phosphate binding site [ion binding]; other site
1151116006571	domain II; other site
1151116006572	domain III; other site
1151116006573	nucleotide binding site [chemical binding]; other site
1151116006574	catalytic site [active]
1151116006575	domain IV; other site
1151116006576	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1151116006577	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1151116006578	active site
1151116006579	8-oxo-dGMP binding site [chemical binding]; other site
1151116006580	nudix motif; other site
1151116006581	metal binding site [ion binding]; metal-binding site
1151116006582	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1151116006583	putative catalytic site [active]
1151116006584	putative phosphate binding site [ion binding]; other site
1151116006585	active site
1151116006586	metal binding site A [ion binding]; metal-binding site
1151116006587	DNA binding site [nucleotide binding]
1151116006588	putative AP binding site [nucleotide binding]; other site
1151116006589	putative metal binding site B [ion binding]; other site
1151116006590	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1151116006591	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1151116006592	PAS domain; Region: PAS; smart00091
1151116006593	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116006594	Walker A motif; other site
1151116006595	ATP binding site [chemical binding]; other site
1151116006596	Walker B motif; other site
1151116006597	arginine finger; other site
1151116006598	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1151116006599	dimer interface [polypeptide binding]; other site
1151116006600	catalytic triad [active]
1151116006601	peroxidatic and resolving cysteines [active]
1151116006602	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1151116006603	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1151116006604	active site
1151116006605	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1151116006606	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1151116006607	peptide binding site [polypeptide binding]; other site
1151116006608	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006609	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116006610	putative substrate translocation pore; other site
1151116006611	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116006612	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116006613	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116006614	putative effector binding pocket; other site
1151116006615	dimerization interface [polypeptide binding]; other site
1151116006616	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1151116006617	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1151116006618	Cl binding site [ion binding]; other site
1151116006619	oligomer interface [polypeptide binding]; other site
1151116006620	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1151116006621	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1151116006622	Ligand Binding Site [chemical binding]; other site
1151116006623	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1151116006624	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1151116006625	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u1; cd11477
1151116006626	Na binding site [ion binding]; other site
1151116006627	Alginate lyase; Region: Alginate_lyase; pfam05426
1151116006628	active site
1151116006629	Alginate Lyase A1-III; enzymatically depolymerizes alginate, a complex copolymer of beta-D-mannuronate and alpha-L-guluronate, by cleaving the beta-(1,4) glycosidic bond; Region: AlgLyase; cl00179
1151116006630	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
1151116006631	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1151116006632	classical (c) SDRs; Region: SDR_c; cd05233
1151116006633	NAD(P) binding site [chemical binding]; other site
1151116006634	active site
1151116006635	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116006636	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116006637	DNA-binding site [nucleotide binding]; DNA binding site
1151116006638	FCD domain; Region: FCD; pfam07729
1151116006639	transcriptional activator RhaS; Provisional; Region: PRK13503
1151116006640	Cupin domain; Region: Cupin_2; cl17218
1151116006641	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116006642	benzoate transport; Region: 2A0115; TIGR00895
1151116006643	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006644	putative substrate translocation pore; other site
1151116006645	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
1151116006646	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
1151116006647	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1151116006648	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1151116006649	dimer interface [polypeptide binding]; other site
1151116006650	PYR/PP interface [polypeptide binding]; other site
1151116006651	TPP binding site [chemical binding]; other site
1151116006652	substrate binding site [chemical binding]; other site
1151116006653	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1151116006654	Domain of unknown function; Region: EKR; smart00890
1151116006655	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1151116006656	4Fe-4S binding domain; Region: Fer4; pfam00037
1151116006657	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1151116006658	TPP-binding site [chemical binding]; other site
1151116006659	dimer interface [polypeptide binding]; other site
1151116006660	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1151116006661	META domain; Region: META; cl01245
1151116006662	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1151116006663	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116006664	Walker A/P-loop; other site
1151116006665	ATP binding site [chemical binding]; other site
1151116006666	Q-loop/lid; other site
1151116006667	ABC transporter signature motif; other site
1151116006668	Walker B; other site
1151116006669	D-loop; other site
1151116006670	H-loop/switch region; other site
1151116006671	TOBE domain; Region: TOBE_2; pfam08402
1151116006672	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1151116006673	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1151116006674	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116006675	dimer interface [polypeptide binding]; other site
1151116006676	conserved gate region; other site
1151116006677	putative PBP binding loops; other site
1151116006678	ABC-ATPase subunit interface; other site
1151116006679	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116006680	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116006681	dimer interface [polypeptide binding]; other site
1151116006682	conserved gate region; other site
1151116006683	putative PBP binding loops; other site
1151116006684	ABC-ATPase subunit interface; other site
1151116006685	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1151116006686	active site
1151116006687	metal binding site [ion binding]; metal-binding site
1151116006688	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1151116006689	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1151116006690	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1151116006691	putative ligand binding site [chemical binding]; other site
1151116006692	putative NAD binding site [chemical binding]; other site
1151116006693	catalytic site [active]
1151116006694	hypothetical protein; Provisional; Region: PRK10695
1151116006695	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1151116006696	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1151116006697	azoreductase; Reviewed; Region: PRK00170
1151116006698	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1151116006699	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1151116006700	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116006701	ATP binding site [chemical binding]; other site
1151116006702	putative Mg++ binding site [ion binding]; other site
1151116006703	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116006704	nucleotide binding region [chemical binding]; other site
1151116006705	ATP-binding site [chemical binding]; other site
1151116006706	Helicase associated domain (HA2); Region: HA2; pfam04408
1151116006707	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1151116006708	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1151116006709	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1151116006710	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1151116006711	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1151116006712	active site
1151116006713	Zn binding site [ion binding]; other site
1151116006714	sensor protein RstB; Provisional; Region: PRK10604
1151116006715	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116006716	dimerization interface [polypeptide binding]; other site
1151116006717	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116006718	dimer interface [polypeptide binding]; other site
1151116006719	phosphorylation site [posttranslational modification]
1151116006720	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116006721	ATP binding site [chemical binding]; other site
1151116006722	Mg2+ binding site [ion binding]; other site
1151116006723	G-X-G motif; other site
1151116006724	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1151116006725	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116006726	active site
1151116006727	phosphorylation site [posttranslational modification]
1151116006728	intermolecular recognition site; other site
1151116006729	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116006730	DNA binding site [nucleotide binding]
1151116006731	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1151116006732	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1151116006733	Cytochrome c; Region: Cytochrom_C; pfam00034
1151116006734	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1151116006735	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1151116006736	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
1151116006737	putative invasin; Provisional; Region: PRK10177
1151116006738	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1151116006739	transcriptional regulator NarL; Provisional; Region: PRK10651
1151116006740	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116006741	active site
1151116006742	phosphorylation site [posttranslational modification]
1151116006743	intermolecular recognition site; other site
1151116006744	dimerization interface [polypeptide binding]; other site
1151116006745	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116006746	DNA binding residues [nucleotide binding]
1151116006747	dimerization interface [polypeptide binding]; other site
1151116006748	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1151116006749	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1151116006750	HAMP domain; Region: HAMP; pfam00672
1151116006751	Histidine kinase; Region: HisKA_3; pfam07730
1151116006752	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116006753	ATP binding site [chemical binding]; other site
1151116006754	Mg2+ binding site [ion binding]; other site
1151116006755	G-X-G motif; other site
1151116006756	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1151116006757	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1151116006758	putative metal binding site [ion binding]; other site
1151116006759	putative homodimer interface [polypeptide binding]; other site
1151116006760	putative homotetramer interface [polypeptide binding]; other site
1151116006761	putative homodimer-homodimer interface [polypeptide binding]; other site
1151116006762	putative allosteric switch controlling residues; other site
1151116006763	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1151116006764	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1151116006765	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1151116006766	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116006767	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116006768	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116006769	dimerization interface [polypeptide binding]; other site
1151116006770	hypothetical protein; Provisional; Region: PRK11667
1151116006771	endonuclease III; Provisional; Region: PRK10702
1151116006772	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1151116006773	minor groove reading motif; other site
1151116006774	helix-hairpin-helix signature motif; other site
1151116006775	substrate binding pocket [chemical binding]; other site
1151116006776	active site
1151116006777	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1151116006778	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1151116006779	electron transport complex protein RnfG; Validated; Region: PRK01908
1151116006780	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1151116006781	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
1151116006782	SLBB domain; Region: SLBB; pfam10531
1151116006783	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1151116006784	electron transport complex protein RnfB; Provisional; Region: PRK05113
1151116006785	Putative Fe-S cluster; Region: FeS; cl17515
1151116006786	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1151116006787	electron transport complex protein RsxA; Provisional; Region: PRK05151
1151116006788	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1151116006789	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1151116006790	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1151116006791	hypothetical protein; Provisional; Region: PRK06185
1151116006792	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1151116006793	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1151116006794	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116006795	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116006796	DNA-binding site [nucleotide binding]; DNA binding site
1151116006797	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1151116006798	hypothetical protein; Provisional; Region: PRK05968
1151116006799	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1151116006800	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116006801	catalytic residue [active]
1151116006802	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1151116006803	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1151116006804	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116006805	dimer interface [polypeptide binding]; other site
1151116006806	conserved gate region; other site
1151116006807	putative PBP binding loops; other site
1151116006808	ABC-ATPase subunit interface; other site
1151116006809	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116006810	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116006811	dimer interface [polypeptide binding]; other site
1151116006812	conserved gate region; other site
1151116006813	putative PBP binding loops; other site
1151116006814	ABC-ATPase subunit interface; other site
1151116006815	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1151116006816	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1151116006817	Walker A/P-loop; other site
1151116006818	ATP binding site [chemical binding]; other site
1151116006819	Q-loop/lid; other site
1151116006820	ABC transporter signature motif; other site
1151116006821	Walker B; other site
1151116006822	D-loop; other site
1151116006823	H-loop/switch region; other site
1151116006824	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1151116006825	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006826	putative substrate translocation pore; other site
1151116006827	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116006828	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116006829	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1151116006830	dimerization interface [polypeptide binding]; other site
1151116006831	substrate binding pocket [chemical binding]; other site
1151116006832	MarR family; Region: MarR_2; cl17246
1151116006833	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1151116006834	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116006835	nucleotide binding site [chemical binding]; other site
1151116006836	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1151116006837	AAA domain; Region: AAA_26; pfam13500
1151116006838	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116006839	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116006840	putative substrate translocation pore; other site
1151116006841	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1151116006842	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116006843	dimer interface [polypeptide binding]; other site
1151116006844	conserved gate region; other site
1151116006845	putative PBP binding loops; other site
1151116006846	ABC-ATPase subunit interface; other site
1151116006847	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116006848	dimer interface [polypeptide binding]; other site
1151116006849	conserved gate region; other site
1151116006850	putative PBP binding loops; other site
1151116006851	ABC-ATPase subunit interface; other site
1151116006852	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1151116006853	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1151116006854	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116006855	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1151116006856	Walker A/P-loop; other site
1151116006857	ATP binding site [chemical binding]; other site
1151116006858	Q-loop/lid; other site
1151116006859	ABC transporter signature motif; other site
1151116006860	Walker B; other site
1151116006861	D-loop; other site
1151116006862	H-loop/switch region; other site
1151116006863	L-arabinose isomerase; Provisional; Region: PRK02929
1151116006864	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1151116006865	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1151116006866	trimer interface [polypeptide binding]; other site
1151116006867	putative substrate binding site [chemical binding]; other site
1151116006868	putative metal binding site [ion binding]; other site
1151116006869	ribulokinase; Provisional; Region: PRK04123
1151116006870	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1151116006871	N- and C-terminal domain interface [polypeptide binding]; other site
1151116006872	active site
1151116006873	MgATP binding site [chemical binding]; other site
1151116006874	catalytic site [active]
1151116006875	metal binding site [ion binding]; metal-binding site
1151116006876	carbohydrate binding site [chemical binding]; other site
1151116006877	homodimer interface [polypeptide binding]; other site
1151116006878	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
1151116006879	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
1151116006880	ligand binding site [chemical binding]; other site
1151116006881	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
1151116006882	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116006883	Walker A/P-loop; other site
1151116006884	ATP binding site [chemical binding]; other site
1151116006885	Q-loop/lid; other site
1151116006886	ABC transporter signature motif; other site
1151116006887	Walker B; other site
1151116006888	D-loop; other site
1151116006889	H-loop/switch region; other site
1151116006890	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116006891	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116006892	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116006893	TM-ABC transporter signature motif; other site
1151116006894	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1151116006895	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1151116006896	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116006897	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116006898	mannonate dehydratase; Provisional; Region: PRK03906
1151116006899	mannonate dehydratase; Region: uxuA; TIGR00695
1151116006900	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116006901	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116006902	DNA-binding site [nucleotide binding]; DNA binding site
1151116006903	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1151116006904	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
1151116006905	Protein of unknown function (DUF2636); Region: DUF2636; cl11897
1151116006906	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1151116006907	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1151116006908	YhjQ protein; Region: YhjQ; pfam06564
1151116006909	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1151116006910	potential frameshift: common BLAST hit: gi|322832863|ref|YP_004212890.1| cellulose synthase catalytic subunit
1151116006911	cellulose synthase regulator protein; Provisional; Region: PRK11114
1151116006912	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1151116006913	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1151116006914	TPR motif; other site
1151116006915	binding surface
1151116006916	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1151116006917	binding surface
1151116006918	TPR motif; other site
1151116006919	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1151116006920	N-formylglutamate amidohydrolase; Region: FGase; cl01522
1151116006921	imidazolonepropionase; Validated; Region: PRK09356
1151116006922	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1151116006923	active site
1151116006924	histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018
1151116006925	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116006926	DNA-binding site [nucleotide binding]; DNA binding site
1151116006927	UTRA domain; Region: UTRA; pfam07702
1151116006928	N-formimino-L-glutamate deiminase; Validated; Region: PRK09229
1151116006929	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_E; cd01313
1151116006930	active site
1151116006931	HutD; Region: HutD; pfam05962
1151116006932	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1151116006933	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116006934	substrate binding pocket [chemical binding]; other site
1151116006935	membrane-bound complex binding site; other site
1151116006936	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1151116006937	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116006938	dimer interface [polypeptide binding]; other site
1151116006939	conserved gate region; other site
1151116006940	putative PBP binding loops; other site
1151116006941	ABC-ATPase subunit interface; other site
1151116006942	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1151116006943	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1151116006944	Walker A/P-loop; other site
1151116006945	ATP binding site [chemical binding]; other site
1151116006946	Q-loop/lid; other site
1151116006947	ABC transporter signature motif; other site
1151116006948	Walker B; other site
1151116006949	D-loop; other site
1151116006950	H-loop/switch region; other site
1151116006951	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1151116006952	active sites [active]
1151116006953	tetramer interface [polypeptide binding]; other site
1151116006954	urocanate hydratase; Provisional; Region: PRK05414
1151116006955	histidinol-phosphate aminotransferase; Provisional; Region: PRK05166
1151116006956	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116006957	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116006958	homodimer interface [polypeptide binding]; other site
1151116006959	catalytic residue [active]
1151116006960	Isopentenyl diphosphate isomerase (BS_ypgA, MTH48 and related proteins) [Coenzyme transport and metabolism]; Region: idi; COG1304
1151116006961	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1151116006962	phosphate binding site [ion binding]; other site
1151116006963	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1151116006964	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1151116006965	active site
1151116006966	NAD binding site [chemical binding]; other site
1151116006967	metal binding site [ion binding]; metal-binding site
1151116006968	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1151116006969	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116006970	NAD(P) binding site [chemical binding]; other site
1151116006971	active site
1151116006972	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1151116006973	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1151116006974	NAD binding site [chemical binding]; other site
1151116006975	dimerization interface [polypeptide binding]; other site
1151116006976	product binding site; other site
1151116006977	substrate binding site [chemical binding]; other site
1151116006978	zinc binding site [ion binding]; other site
1151116006979	catalytic residues [active]
1151116006980	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1151116006981	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1151116006982	Walker A/P-loop; other site
1151116006983	ATP binding site [chemical binding]; other site
1151116006984	Q-loop/lid; other site
1151116006985	ABC transporter signature motif; other site
1151116006986	Walker B; other site
1151116006987	D-loop; other site
1151116006988	H-loop/switch region; other site
1151116006989	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1151116006990	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116006991	dimer interface [polypeptide binding]; other site
1151116006992	conserved gate region; other site
1151116006993	putative PBP binding loops; other site
1151116006994	ABC-ATPase subunit interface; other site
1151116006995	potential frameshift: common BLAST hit: gi|317053651|ref|YP_004118785.1| NMT1/THI5 like domain-containing protein
1151116006996	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116006997	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116006998	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116006999	dimerization interface [polypeptide binding]; other site
1151116007000	argininosuccinate lyase; Provisional; Region: PRK00855
1151116007001	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1151116007002	active sites [active]
1151116007003	tetramer interface [polypeptide binding]; other site
1151116007004	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116007005	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007006	dimer interface [polypeptide binding]; other site
1151116007007	conserved gate region; other site
1151116007008	putative PBP binding loops; other site
1151116007009	ABC-ATPase subunit interface; other site
1151116007010	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116007011	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116007012	Walker A/P-loop; other site
1151116007013	ATP binding site [chemical binding]; other site
1151116007014	Q-loop/lid; other site
1151116007015	ABC transporter signature motif; other site
1151116007016	Walker B; other site
1151116007017	D-loop; other site
1151116007018	H-loop/switch region; other site
1151116007019	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116007020	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116007021	substrate binding pocket [chemical binding]; other site
1151116007022	membrane-bound complex binding site; other site
1151116007023	hinge residues; other site
1151116007024	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1151116007025	active site
1151116007026	catalytic site [active]
1151116007027	Zn binding site [ion binding]; other site
1151116007028	tetramer interface [polypeptide binding]; other site
1151116007029	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
1151116007030	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1151116007031	active site
1151116007032	catalytic site [active]
1151116007033	Zn binding site [ion binding]; other site
1151116007034	tetramer interface [polypeptide binding]; other site
1151116007035	Uncharacterized protein involved in propionate catabolism [General function prediction only]; Region: PrpD; COG2079
1151116007036	putative oxidoreductase; Provisional; Region: PRK11579
1151116007037	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1151116007038	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1151116007039	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1151116007040	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1151116007041	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1151116007042	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1151116007043	active site
1151116007044	purine riboside binding site [chemical binding]; other site
1151116007045	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1151116007046	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116007047	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116007048	homodimer interface [polypeptide binding]; other site
1151116007049	catalytic residue [active]
1151116007050	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1151116007051	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1151116007052	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116007053	active site turn [active]
1151116007054	phosphorylation site [posttranslational modification]
1151116007055	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1151116007056	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116007057	DNA binding site [nucleotide binding]
1151116007058	domain linker motif; other site
1151116007059	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1151116007060	YebF-like protein; Region: YebF; cl10126
1151116007061	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1151116007062	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1151116007063	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
1151116007064	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
1151116007065	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
1151116007066	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1151116007067	MarR family; Region: MarR_2; pfam12802
1151116007068	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1151116007069	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_10; cd07251
1151116007070	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1151116007071	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1151116007072	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1151116007073	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
1151116007074	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1151116007075	conserved cys residue [active]
1151116007076	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116007077	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1151116007078	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116007079	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116007080	catalytic residue [active]
1151116007081	Cupin domain; Region: Cupin_2; cl17218
1151116007082	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1151116007083	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1151116007084	active site
1151116007085	metal binding site [ion binding]; metal-binding site
1151116007086	hexamer interface [polypeptide binding]; other site
1151116007087	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
1151116007088	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137
1151116007089	conserved cys residue [active]
1151116007090	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116007091	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1151116007092	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1151116007093	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1151116007094	Class II fumarases; Region: Fumarase_classII; cd01362
1151116007095	active site
1151116007096	tetramer interface [polypeptide binding]; other site
1151116007097	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1151116007098	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1151116007099	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1151116007100	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1151116007101	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1151116007102	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1151116007103	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1151116007104	Walker A/P-loop; other site
1151116007105	ATP binding site [chemical binding]; other site
1151116007106	Q-loop/lid; other site
1151116007107	ABC transporter signature motif; other site
1151116007108	Walker B; other site
1151116007109	D-loop; other site
1151116007110	H-loop/switch region; other site
1151116007111	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1151116007112	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1151116007113	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116007114	DNA-binding site [nucleotide binding]; DNA binding site
1151116007115	FCD domain; Region: FCD; pfam07729
1151116007116	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1151116007117	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007118	dimer interface [polypeptide binding]; other site
1151116007119	conserved gate region; other site
1151116007120	putative PBP binding loops; other site
1151116007121	ABC-ATPase subunit interface; other site
1151116007122	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007123	dimer interface [polypeptide binding]; other site
1151116007124	conserved gate region; other site
1151116007125	putative PBP binding loops; other site
1151116007126	ABC-ATPase subunit interface; other site
1151116007127	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1151116007128	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1151116007129	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1151116007130	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116007131	Walker A/P-loop; other site
1151116007132	ATP binding site [chemical binding]; other site
1151116007133	Q-loop/lid; other site
1151116007134	ABC transporter signature motif; other site
1151116007135	Walker B; other site
1151116007136	D-loop; other site
1151116007137	H-loop/switch region; other site
1151116007138	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1151116007139	xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964
1151116007140	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1151116007141	xanthine dehydrogenase, molybdopterin binding subunit; Region: xanthine_xdhB; TIGR02965
1151116007142	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1151116007143	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1151116007144	xanthine dehydrogenase, small subunit; Region: xanthine_xdhA; TIGR02963
1151116007145	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1151116007146	catalytic loop [active]
1151116007147	iron binding site [ion binding]; other site
1151116007148	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1151116007149	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1151116007150	pyrimidine utilization regulatory protein R; Region: RutR; TIGR03613
1151116007151	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116007152	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1151116007153	guanine deaminase; Provisional; Region: PRK09228
1151116007154	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
1151116007155	active site
1151116007156	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1151116007157	non-specific DNA interactions [nucleotide binding]; other site
1151116007158	DNA binding site [nucleotide binding]
1151116007159	sequence specific DNA binding site [nucleotide binding]; other site
1151116007160	putative cAMP binding site [chemical binding]; other site
1151116007161	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1151116007162	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116007163	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1151116007164	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1151116007165	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007166	dimer interface [polypeptide binding]; other site
1151116007167	conserved gate region; other site
1151116007168	putative PBP binding loops; other site
1151116007169	ABC-ATPase subunit interface; other site
1151116007170	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116007171	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007172	dimer interface [polypeptide binding]; other site
1151116007173	conserved gate region; other site
1151116007174	putative PBP binding loops; other site
1151116007175	ABC-ATPase subunit interface; other site
1151116007176	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116007177	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1151116007178	substrate binding site [chemical binding]; other site
1151116007179	ATP binding site [chemical binding]; other site
1151116007180	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1151116007181	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116007182	Walker A/P-loop; other site
1151116007183	ATP binding site [chemical binding]; other site
1151116007184	Q-loop/lid; other site
1151116007185	ABC transporter signature motif; other site
1151116007186	Walker B; other site
1151116007187	D-loop; other site
1151116007188	H-loop/switch region; other site
1151116007189	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116007190	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116007191	active site
1151116007192	catalytic tetrad [active]
1151116007193	malonic semialdehyde reductase; Provisional; Region: PRK10538
1151116007194	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1151116007195	putative NAD(P) binding site [chemical binding]; other site
1151116007196	homodimer interface [polypeptide binding]; other site
1151116007197	homotetramer interface [polypeptide binding]; other site
1151116007198	active site
1151116007199	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1151116007200	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116007201	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116007202	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116007203	dimerization interface [polypeptide binding]; other site
1151116007204	hypothetical protein; Provisional; Region: PRK02237
1151116007205	hypothetical protein; Provisional; Region: PRK13659
1151116007206	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1151116007207	hypothetical protein; Provisional; Region: PRK10515
1151116007208	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1151116007209	active site residue [active]
1151116007210	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1151116007211	active site residue [active]
1151116007212	Member of the Rhodanese Homology Domain superfamily, repeat 3. This CD includes putative rhodanese-related sulfurtransferases which contain 4 copies of the Rhodanese Homology Domain. This CD aligns the 3rd repeat which does not contain the putative...; Region: 4RHOD_Repeat_3; cd01534
1151116007213	active site residue [active]
1151116007214	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1151116007215	active site residue [active]
1151116007216	Predicted metal-dependent enzyme of the double-stranded beta helix superfamily [General function prediction only]; Region: COG5553
1151116007217	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116007218	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116007219	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116007220	dimerization interface [polypeptide binding]; other site
1151116007221	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1151116007222	alkanesulfonate monooxygenase, FMNH(2)-dependent; Region: alk_sulf_monoox; TIGR03565
1151116007223	dimer interface [polypeptide binding]; other site
1151116007224	active site
1151116007225	non-prolyl cis peptide bond; other site
1151116007226	insertion regions; other site
1151116007227	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1151116007228	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116007229	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1151116007230	membrane-bound complex binding site; other site
1151116007231	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1151116007232	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
1151116007233	conserved cys residue [active]
1151116007234	oxalate/formate antiporter; Region: oxa_formateAnti; TIGR04259
1151116007235	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116007236	putative substrate translocation pore; other site
1151116007237	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1151116007238	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1151116007239	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1151116007240	oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701
1151116007241	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
1151116007242	putative molybdopterin cofactor binding site [chemical binding]; other site
1151116007243	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
1151116007244	putative molybdopterin cofactor binding site; other site
1151116007245	exoribonuclease II; Provisional; Region: PRK05054
1151116007246	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1151116007247	RNB domain; Region: RNB; pfam00773
1151116007248	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1151116007249	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
1151116007250	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116007251	The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413
1151116007252	substrate binding site [chemical binding]; other site
1151116007253	dimerization interface [polypeptide binding]; other site
1151116007254	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1151116007255	Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase; Region: HPPR; cd12156
1151116007256	putative ligand binding site [chemical binding]; other site
1151116007257	NAD binding site [chemical binding]; other site
1151116007258	catalytic site [active]
1151116007259	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1151116007260	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1151116007261	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1151116007262	active site
1151116007263	catalytic site [active]
1151116007264	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1151116007265	ApbE family; Region: ApbE; pfam02424
1151116007266	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1151116007267	Smr domain; Region: Smr; pfam01713
1151116007268	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1151116007269	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116007270	active site
1151116007271	motif I; other site
1151116007272	motif II; other site
1151116007273	putative glucosyl-3-phosphoglycerate synthase; Provisional; Region: PRK13915
1151116007274	Integral membrane protein TerC family; Region: TerC; cl10468
1151116007275	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1151116007276	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1151116007277	ligand binding site [chemical binding]; other site
1151116007278	flexible hinge region; other site
1151116007279	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1151116007280	putative switch regulator; other site
1151116007281	non-specific DNA interactions [nucleotide binding]; other site
1151116007282	DNA binding site [nucleotide binding]
1151116007283	sequence specific DNA binding site [nucleotide binding]; other site
1151116007284	putative cAMP binding site [chemical binding]; other site
1151116007285	universal stress protein UspE; Provisional; Region: PRK11175
1151116007286	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1151116007287	Ligand Binding Site [chemical binding]; other site
1151116007288	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1151116007289	Ligand Binding Site [chemical binding]; other site
1151116007290	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1151116007291	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1151116007292	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1151116007293	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1151116007294	ligand binding site [chemical binding]; other site
1151116007295	homodimer interface [polypeptide binding]; other site
1151116007296	NAD(P) binding site [chemical binding]; other site
1151116007297	trimer interface B [polypeptide binding]; other site
1151116007298	trimer interface A [polypeptide binding]; other site
1151116007299	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1151116007300	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116007301	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116007302	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116007303	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
1151116007304	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
1151116007305	active site
1151116007306	dimer interface [polypeptide binding]; other site
1151116007307	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1151116007308	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1151116007309	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116007310	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007311	putative PBP binding loops; other site
1151116007312	dimer interface [polypeptide binding]; other site
1151116007313	ABC-ATPase subunit interface; other site
1151116007314	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116007315	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1151116007316	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007317	dimer interface [polypeptide binding]; other site
1151116007318	conserved gate region; other site
1151116007319	putative PBP binding loops; other site
1151116007320	ABC-ATPase subunit interface; other site
1151116007321	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116007322	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007323	Walker A/P-loop; other site
1151116007324	ATP binding site [chemical binding]; other site
1151116007325	Q-loop/lid; other site
1151116007326	ABC transporter signature motif; other site
1151116007327	Walker B; other site
1151116007328	D-loop; other site
1151116007329	H-loop/switch region; other site
1151116007330	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116007331	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116007332	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007333	Walker A/P-loop; other site
1151116007334	ATP binding site [chemical binding]; other site
1151116007335	Q-loop/lid; other site
1151116007336	ABC transporter signature motif; other site
1151116007337	Walker B; other site
1151116007338	D-loop; other site
1151116007339	H-loop/switch region; other site
1151116007340	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1151116007341	Beta-lactamase; Region: Beta-lactamase; pfam00144
1151116007342	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1151116007343	4Fe-4S binding domain; Region: Fer4; pfam00037
1151116007344	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1151116007345	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1151116007346	Domain of unknown function (DUF336); Region: DUF336; pfam03928
1151116007347	Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318
1151116007348	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1151116007349	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1151116007350	Cytochrome c; Region: Cytochrom_C; pfam00034
1151116007351	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1151116007352	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116007353	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116007354	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116007355	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1151116007356	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1151116007357	putative transporter; Provisional; Region: PRK11660
1151116007358	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1151116007359	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1151116007360	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1151116007361	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1151116007362	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1151116007363	hypothetical protein; Provisional; Region: PRK10941
1151116007364	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1151116007365	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1151116007366	binding surface
1151116007367	TPR motif; other site
1151116007368	Invasion gene expression up-regulator, SirB; Region: SirB; pfam04247
1151116007369	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1151116007370	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116007371	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1151116007372	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1151116007373	RF-1 domain; Region: RF-1; pfam00472
1151116007374	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1151116007375	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1151116007376	tRNA; other site
1151116007377	putative tRNA binding site [nucleotide binding]; other site
1151116007378	putative NADP binding site [chemical binding]; other site
1151116007379	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1151116007380	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
1151116007381	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1151116007382	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1151116007383	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1151116007384	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1151116007385	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1151116007386	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1151116007387	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1151116007388	active site
1151116007389	hypothetical protein; Provisional; Region: PRK10692
1151116007390	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1151116007391	putative active site [active]
1151116007392	catalytic residue [active]
1151116007393	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
1151116007394	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1151116007395	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1151116007396	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1151116007397	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1151116007398	HflC protein; Region: hflC; TIGR01932
1151116007399	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1151116007400	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1151116007401	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1151116007402	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1151116007403	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1151116007404	GTP-binding protein YchF; Reviewed; Region: PRK09601
1151116007405	YchF GTPase; Region: YchF; cd01900
1151116007406	G1 box; other site
1151116007407	GTP/Mg2+ binding site [chemical binding]; other site
1151116007408	Switch I region; other site
1151116007409	G2 box; other site
1151116007410	Switch II region; other site
1151116007411	G3 box; other site
1151116007412	G4 box; other site
1151116007413	G5 box; other site
1151116007414	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1151116007415	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1151116007416	active site
1151116007417	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1151116007418	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116007419	N-terminal plug; other site
1151116007420	ligand-binding site [chemical binding]; other site
1151116007421	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116007422	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116007423	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116007424	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1151116007425	HAMP domain; Region: HAMP; pfam00672
1151116007426	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116007427	dimer interface [polypeptide binding]; other site
1151116007428	phosphorylation site [posttranslational modification]
1151116007429	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116007430	ATP binding site [chemical binding]; other site
1151116007431	Mg2+ binding site [ion binding]; other site
1151116007432	G-X-G motif; other site
1151116007433	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1151116007434	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116007435	active site
1151116007436	phosphorylation site [posttranslational modification]
1151116007437	intermolecular recognition site; other site
1151116007438	dimerization interface [polypeptide binding]; other site
1151116007439	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116007440	DNA binding site [nucleotide binding]
1151116007441	potential frameshift: common BLAST hit: gi|322833004|ref|YP_004213031.1| glycosyltransferase 36 associated
1151116007442	potential frameshift: common BLAST hit: gi|322833004|ref|YP_004213031.1| glycosyltransferase 36 associated
1151116007443	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1151116007444	FMN binding site [chemical binding]; other site
1151116007445	dimer interface [polypeptide binding]; other site
1151116007446	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116007447	metal binding site [ion binding]; metal-binding site
1151116007448	active site
1151116007449	I-site; other site
1151116007450	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116007451	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1151116007452	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1151116007453	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116007454	Coenzyme A binding pocket [chemical binding]; other site
1151116007455	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1151116007456	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116007457	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1151116007458	putative active site [active]
1151116007459	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116007460	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116007461	substrate binding pocket [chemical binding]; other site
1151116007462	membrane-bound complex binding site; other site
1151116007463	hinge residues; other site
1151116007464	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1151116007465	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
1151116007466	urea carboxylase-associated protein 1; Region: urea_degr_1; TIGR03424
1151116007467	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
1151116007468	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007469	dimer interface [polypeptide binding]; other site
1151116007470	conserved gate region; other site
1151116007471	putative PBP binding loops; other site
1151116007472	ABC-ATPase subunit interface; other site
1151116007473	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007474	dimer interface [polypeptide binding]; other site
1151116007475	conserved gate region; other site
1151116007476	putative PBP binding loops; other site
1151116007477	ABC-ATPase subunit interface; other site
1151116007478	Domain of unknown function (DUF1989); Region: DUF1989; pfam09347
1151116007479	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
1151116007480	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
1151116007481	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116007482	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116007483	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116007484	dimerization interface [polypeptide binding]; other site
1151116007485	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116007486	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116007487	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116007488	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1151116007489	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1151116007490	putative active site [active]
1151116007491	putative FMN binding site [chemical binding]; other site
1151116007492	putative substrate binding site [chemical binding]; other site
1151116007493	putative catalytic residue [active]
1151116007494	FMN-binding domain; Region: FMN_bind; cl01081
1151116007495	fumarate reductase flavoprotein subunit; Validated; Region: PRK06481
1151116007496	L-aspartate oxidase; Provisional; Region: PRK06175
1151116007497	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1151116007498	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1151116007499	transmembrane helices; other site
1151116007500	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1151116007501	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116007502	DNA-binding site [nucleotide binding]; DNA binding site
1151116007503	FCD domain; Region: FCD; pfam07729
1151116007504	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116007505	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_2; cd08498
1151116007506	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116007507	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007508	dimer interface [polypeptide binding]; other site
1151116007509	conserved gate region; other site
1151116007510	putative PBP binding loops; other site
1151116007511	ABC-ATPase subunit interface; other site
1151116007512	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116007513	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007514	dimer interface [polypeptide binding]; other site
1151116007515	conserved gate region; other site
1151116007516	putative PBP binding loops; other site
1151116007517	ABC-ATPase subunit interface; other site
1151116007518	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
1151116007519	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1151116007520	metal binding site [ion binding]; metal-binding site
1151116007521	D-cysteine desulfhydrase; Validated; Region: PRK03910
1151116007522	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1151116007523	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116007524	catalytic residue [active]
1151116007525	2,3-diaminopropionate biosynthesis protein SbnB; Region: dehyd_SbnB_fam; TIGR03944
1151116007526	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
1151116007527	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1151116007528	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1151116007529	active site residue [active]
1151116007530	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1151116007531	active site residue [active]
1151116007532	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1151116007533	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007534	Walker A/P-loop; other site
1151116007535	ATP binding site [chemical binding]; other site
1151116007536	Q-loop/lid; other site
1151116007537	ABC transporter signature motif; other site
1151116007538	Walker B; other site
1151116007539	D-loop; other site
1151116007540	H-loop/switch region; other site
1151116007541	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116007542	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007543	Walker A/P-loop; other site
1151116007544	ATP binding site [chemical binding]; other site
1151116007545	Q-loop/lid; other site
1151116007546	ABC transporter signature motif; other site
1151116007547	Walker B; other site
1151116007548	D-loop; other site
1151116007549	H-loop/switch region; other site
1151116007550	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116007551	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N; pfam00033
1151116007552	glutathionine S-transferase; Provisional; Region: PRK10542
1151116007553	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1151116007554	C-terminal domain interface [polypeptide binding]; other site
1151116007555	GSH binding site (G-site) [chemical binding]; other site
1151116007556	dimer interface [polypeptide binding]; other site
1151116007557	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1151116007558	dimer interface [polypeptide binding]; other site
1151116007559	N-terminal domain interface [polypeptide binding]; other site
1151116007560	substrate binding pocket (H-site) [chemical binding]; other site
1151116007561	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116007562	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116007563	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116007564	dimerization interface [polypeptide binding]; other site
1151116007565	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1151116007566	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1151116007567	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116007568	potential frameshift: common BLAST hit: gi|322833034|ref|YP_004213061.1| short-chain dehydrogenase/reductase SDR
1151116007569	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1151116007570	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1151116007571	catalytic site [active]
1151116007572	Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545
1151116007573	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1151116007574	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
1151116007575	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116007576	dimerization interface [polypeptide binding]; other site
1151116007577	putative DNA binding site [nucleotide binding]; other site
1151116007578	putative Zn2+ binding site [ion binding]; other site
1151116007579	AsnC family; Region: AsnC_trans_reg; pfam01037
1151116007580	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1151116007581	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116007582	dimer interface [polypeptide binding]; other site
1151116007583	phosphorylation site [posttranslational modification]
1151116007584	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116007585	ATP binding site [chemical binding]; other site
1151116007586	Mg2+ binding site [ion binding]; other site
1151116007587	G-X-G motif; other site
1151116007588	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1151116007589	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116007590	active site
1151116007591	phosphorylation site [posttranslational modification]
1151116007592	intermolecular recognition site; other site
1151116007593	dimerization interface [polypeptide binding]; other site
1151116007594	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116007595	DNA binding site [nucleotide binding]
1151116007596	MltA-interacting protein MipA; Region: MipA; cl01504
1151116007597	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
1151116007598	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116007599	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1151116007600	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116007601	putative substrate translocation pore; other site
1151116007602	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116007603	Coenzyme A binding pocket [chemical binding]; other site
1151116007604	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1151116007605	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1151116007606	formate dehydrogenase region TAT target; Region: formate_TAT; TIGR02811
1151116007607	Dyp-type peroxidase family; Region: Dyp_perox; cl01067
1151116007608	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
1151116007609	Imelysin; Region: Peptidase_M75; pfam09375
1151116007610	Iron permease FTR1 family; Region: FTR1; cl00475
1151116007611	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1151116007612	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1151116007613	Ligand binding site; other site
1151116007614	Putative Catalytic site; other site
1151116007615	DXD motif; other site
1151116007616	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1151116007617	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1151116007618	Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; Region: Glucosylceramide_synthase; cd02520
1151116007619	ligand binding site; other site
1151116007620	Glycosyl transferase family 21; Region: Glyco_transf_21; pfam13506
1151116007621	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1151116007622	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1151116007623	active site
1151116007624	intersubunit interface [polypeptide binding]; other site
1151116007625	catalytic residue [active]
1151116007626	phosphogluconate dehydratase; Validated; Region: PRK09054
1151116007627	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1151116007628	low affinity gluconate transporter; Provisional; Region: PRK10472
1151116007629	GntP family permease; Region: GntP_permease; pfam02447
1151116007630	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1151116007631	ATP-binding site [chemical binding]; other site
1151116007632	Gluconate-6-phosphate binding site [chemical binding]; other site
1151116007633	Shikimate kinase; Region: SKI; pfam01202
1151116007634	hypothetical protein; Provisional; Region: PRK09929
1151116007635	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
1151116007636	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116007637	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116007638	EamA-like transporter family; Region: EamA; pfam00892
1151116007639	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1151116007640	EamA-like transporter family; Region: EamA; pfam00892
1151116007641	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1151116007642	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1151116007643	putative NAD(P) binding site [chemical binding]; other site
1151116007644	putative substrate binding site [chemical binding]; other site
1151116007645	catalytic Zn binding site [ion binding]; other site
1151116007646	structural Zn binding site [ion binding]; other site
1151116007647	dimer interface [polypeptide binding]; other site
1151116007648	histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018
1151116007649	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116007650	DNA-binding site [nucleotide binding]; DNA binding site
1151116007651	UTRA domain; Region: UTRA; pfam07702
1151116007652	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
1151116007653	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1151116007654	substrate binding site [chemical binding]; other site
1151116007655	oxyanion hole (OAH) forming residues; other site
1151116007656	trimer interface [polypeptide binding]; other site
1151116007657	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1151116007658	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1151116007659	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1151116007660	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
1151116007661	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1151116007662	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1151116007663	active sites [active]
1151116007664	tetramer interface [polypeptide binding]; other site
1151116007665	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1151116007666	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
1151116007667	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007668	dimer interface [polypeptide binding]; other site
1151116007669	conserved gate region; other site
1151116007670	ABC-ATPase subunit interface; other site
1151116007671	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1151116007672	glycine betaine/L-proline transport ATP binding subunit; Region: proV; TIGR01186
1151116007673	Walker A/P-loop; other site
1151116007674	ATP binding site [chemical binding]; other site
1151116007675	Q-loop/lid; other site
1151116007676	ABC transporter signature motif; other site
1151116007677	Walker B; other site
1151116007678	D-loop; other site
1151116007679	H-loop/switch region; other site
1151116007680	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1151116007681	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116007682	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
1151116007683	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116007684	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116007685	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116007686	putative effector binding pocket; other site
1151116007687	dimerization interface [polypeptide binding]; other site
1151116007688	Pirin-related protein [General function prediction only]; Region: COG1741
1151116007689	Pirin; Region: Pirin; pfam02678
1151116007690	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
1151116007691	Adenylosuccinate lyase C-terminus; Region: ADSL_C; cl17237
1151116007692	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1151116007693	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116007694	Coenzyme A binding pocket [chemical binding]; other site
1151116007695	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1151116007696	Coenzyme A binding pocket [chemical binding]; other site
1151116007697	nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095
1151116007698	FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860
1151116007699	active site
1151116007700	non-prolyl cis peptide bond; other site
1151116007701	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116007702	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116007703	Walker A/P-loop; other site
1151116007704	ATP binding site [chemical binding]; other site
1151116007705	Q-loop/lid; other site
1151116007706	ABC transporter signature motif; other site
1151116007707	Walker B; other site
1151116007708	D-loop; other site
1151116007709	H-loop/switch region; other site
1151116007710	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007711	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116007712	dimer interface [polypeptide binding]; other site
1151116007713	conserved gate region; other site
1151116007714	putative PBP binding loops; other site
1151116007715	ABC-ATPase subunit interface; other site
1151116007716	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116007717	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116007718	substrate binding pocket [chemical binding]; other site
1151116007719	membrane-bound complex binding site; other site
1151116007720	hinge residues; other site
1151116007721	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1151116007722	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007723	dimer interface [polypeptide binding]; other site
1151116007724	conserved gate region; other site
1151116007725	putative PBP binding loops; other site
1151116007726	ABC-ATPase subunit interface; other site
1151116007727	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007728	dimer interface [polypeptide binding]; other site
1151116007729	conserved gate region; other site
1151116007730	putative PBP binding loops; other site
1151116007731	ABC-ATPase subunit interface; other site
1151116007732	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116007733	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116007734	Walker A/P-loop; other site
1151116007735	ATP binding site [chemical binding]; other site
1151116007736	Q-loop/lid; other site
1151116007737	ABC transporter signature motif; other site
1151116007738	Walker B; other site
1151116007739	D-loop; other site
1151116007740	H-loop/switch region; other site
1151116007741	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116007742	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116007743	substrate binding pocket [chemical binding]; other site
1151116007744	membrane-bound complex binding site; other site
1151116007745	hinge residues; other site
1151116007746	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1151116007747	active site
1151116007748	SAM binding site [chemical binding]; other site
1151116007749	homodimer interface [polypeptide binding]; other site
1151116007750	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1151116007751	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1151116007752	[4Fe-4S] binding site [ion binding]; other site
1151116007753	molybdopterin cofactor binding site; other site
1151116007754	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1151116007755	molybdopterin cofactor binding site; other site
1151116007756	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1151116007757	potential frameshift: common BLAST hit: gi|322833095|ref|YP_004213122.1| nitrite reductase (NAD(P)H) large subunit
1151116007758	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1151116007759	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1151116007760	Walker A/P-loop; other site
1151116007761	ATP binding site [chemical binding]; other site
1151116007762	Q-loop/lid; other site
1151116007763	ABC transporter signature motif; other site
1151116007764	Walker B; other site
1151116007765	D-loop; other site
1151116007766	H-loop/switch region; other site
1151116007767	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1151116007768	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007769	dimer interface [polypeptide binding]; other site
1151116007770	conserved gate region; other site
1151116007771	putative PBP binding loops; other site
1151116007772	ABC-ATPase subunit interface; other site
1151116007773	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1151116007774	NMT1-like family; Region: NMT1_2; pfam13379
1151116007775	Nitrate and nitrite sensing; Region: NIT; pfam08376
1151116007776	ANTAR domain; Region: ANTAR; pfam03861
1151116007777	Flagellin N-methylase; Region: FliB; pfam03692
1151116007778	Predicted transcriptional regulator [Transcription]; Region: COG2378
1151116007779	HTH domain; Region: HTH_11; cl17392
1151116007780	WYL domain; Region: WYL; pfam13280
1151116007781	Sugar-binding cellulase-like; Region: Cellulase-like; pfam12876
1151116007782	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
1151116007783	beta-galactosidase; Region: BGL; TIGR03356
1151116007784	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
1151116007785	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116007786	active site turn [active]
1151116007787	phosphorylation site [posttranslational modification]
1151116007788	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1151116007789	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116007790	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116007791	DNA binding site [nucleotide binding]
1151116007792	domain linker motif; other site
1151116007793	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1151116007794	dimerization interface (closed form) [polypeptide binding]; other site
1151116007795	ligand binding site [chemical binding]; other site
1151116007796	Protein of unknown function (DUF3274); Region: DUF3274; pfam11678
1151116007797	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116007798	PAS domain; Region: PAS_9; pfam13426
1151116007799	putative active site [active]
1151116007800	heme pocket [chemical binding]; other site
1151116007801	PAS domain; Region: PAS_9; pfam13426
1151116007802	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116007803	metal binding site [ion binding]; metal-binding site
1151116007804	active site
1151116007805	I-site; other site
1151116007806	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116007807	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116007808	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116007809	DNA-binding site [nucleotide binding]; DNA binding site
1151116007810	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1151116007811	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1151116007812	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007813	Walker A/P-loop; other site
1151116007814	ATP binding site [chemical binding]; other site
1151116007815	Q-loop/lid; other site
1151116007816	ABC transporter signature motif; other site
1151116007817	Walker B; other site
1151116007818	D-loop; other site
1151116007819	H-loop/switch region; other site
1151116007820	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1151116007821	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1151116007822	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007823	Walker A/P-loop; other site
1151116007824	ATP binding site [chemical binding]; other site
1151116007825	Q-loop/lid; other site
1151116007826	ABC transporter signature motif; other site
1151116007827	Walker B; other site
1151116007828	D-loop; other site
1151116007829	H-loop/switch region; other site
1151116007830	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1151116007831	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116007832	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_5; cd08511
1151116007833	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116007834	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007835	dimer interface [polypeptide binding]; other site
1151116007836	conserved gate region; other site
1151116007837	ABC-ATPase subunit interface; other site
1151116007838	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116007839	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1151116007840	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007841	dimer interface [polypeptide binding]; other site
1151116007842	conserved gate region; other site
1151116007843	putative PBP binding loops; other site
1151116007844	ABC-ATPase subunit interface; other site
1151116007845	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1151116007846	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1151116007847	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1151116007848	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1151116007849	inhibitor site; inhibition site
1151116007850	active site
1151116007851	dimer interface [polypeptide binding]; other site
1151116007852	catalytic residue [active]
1151116007853	siderophore-iron reductase FhuF; Region: Fe_III_red_FhuF; TIGR03951
1151116007854	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1151116007855	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1151116007856	metabolite-proton symporter; Region: 2A0106; TIGR00883
1151116007857	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116007858	putative substrate translocation pore; other site
1151116007859	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1151116007860	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116007861	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1151116007862	putative active site [active]
1151116007863	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1151116007864	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1151116007865	active site
1151116007866	NAD binding site [chemical binding]; other site
1151116007867	metal binding site [ion binding]; metal-binding site
1151116007868	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1151116007869	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1151116007870	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1151116007871	active site
1151116007872	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
1151116007873	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1151116007874	metal binding site [ion binding]; metal-binding site
1151116007875	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1151116007876	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007877	Walker A/P-loop; other site
1151116007878	ATP binding site [chemical binding]; other site
1151116007879	Q-loop/lid; other site
1151116007880	ABC transporter signature motif; other site
1151116007881	Walker B; other site
1151116007882	D-loop; other site
1151116007883	H-loop/switch region; other site
1151116007884	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116007885	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007886	Walker A/P-loop; other site
1151116007887	ATP binding site [chemical binding]; other site
1151116007888	Q-loop/lid; other site
1151116007889	ABC transporter signature motif; other site
1151116007890	Walker B; other site
1151116007891	D-loop; other site
1151116007892	H-loop/switch region; other site
1151116007893	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116007894	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007895	dimer interface [polypeptide binding]; other site
1151116007896	conserved gate region; other site
1151116007897	putative PBP binding loops; other site
1151116007898	ABC-ATPase subunit interface; other site
1151116007899	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116007900	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007901	dimer interface [polypeptide binding]; other site
1151116007902	conserved gate region; other site
1151116007903	putative PBP binding loops; other site
1151116007904	ABC-ATPase subunit interface; other site
1151116007905	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116007906	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_17; cd08503
1151116007907	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
1151116007908	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1151116007909	metal binding site [ion binding]; metal-binding site
1151116007910	dimer interface [polypeptide binding]; other site
1151116007911	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1151116007912	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116007913	DNA-binding site [nucleotide binding]; DNA binding site
1151116007914	UTRA domain; Region: UTRA; pfam07702
1151116007915	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116007916	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116007917	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116007918	dimerization interface [polypeptide binding]; other site
1151116007919	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA_1; cd08663
1151116007920	SxDxEG motif; other site
1151116007921	active site
1151116007922	metal binding site [ion binding]; metal-binding site
1151116007923	homopentamer interface [polypeptide binding]; other site
1151116007924	L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active...; Region: DmpA; cd02253
1151116007925	homodimer interface [polypeptide binding]; other site
1151116007926	homotetramer interface [polypeptide binding]; other site
1151116007927	active site pocket [active]
1151116007928	cleavage site
1151116007929	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1151116007930	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007931	dimer interface [polypeptide binding]; other site
1151116007932	conserved gate region; other site
1151116007933	putative PBP binding loops; other site
1151116007934	ABC-ATPase subunit interface; other site
1151116007935	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1151116007936	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116007937	dimer interface [polypeptide binding]; other site
1151116007938	conserved gate region; other site
1151116007939	putative PBP binding loops; other site
1151116007940	ABC-ATPase subunit interface; other site
1151116007941	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1151116007942	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1151116007943	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1151116007944	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007945	Walker A/P-loop; other site
1151116007946	ATP binding site [chemical binding]; other site
1151116007947	Q-loop/lid; other site
1151116007948	ABC transporter signature motif; other site
1151116007949	Walker B; other site
1151116007950	D-loop; other site
1151116007951	H-loop/switch region; other site
1151116007952	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1151116007953	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116007954	Walker A/P-loop; other site
1151116007955	ATP binding site [chemical binding]; other site
1151116007956	Q-loop/lid; other site
1151116007957	ABC transporter signature motif; other site
1151116007958	Walker B; other site
1151116007959	D-loop; other site
1151116007960	H-loop/switch region; other site
1151116007961	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1151116007962	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1151116007963	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1151116007964	active site
1151116007965	Protein of unknown function (DUF1611); Region: DUF1611; pfam07755
1151116007966	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1151116007967	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1151116007968	trimer interface [polypeptide binding]; other site
1151116007969	eyelet of channel; other site
1151116007970	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1151116007971	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1151116007972	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1151116007973	Walker A/P-loop; other site
1151116007974	ATP binding site [chemical binding]; other site
1151116007975	Q-loop/lid; other site
1151116007976	ABC transporter signature motif; other site
1151116007977	Walker B; other site
1151116007978	D-loop; other site
1151116007979	H-loop/switch region; other site
1151116007980	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1151116007981	D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558
1151116007982	homodimer interface [polypeptide binding]; other site
1151116007983	substrate-cofactor binding pocket; other site
1151116007984	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116007985	catalytic residue [active]
1151116007986	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1151116007987	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1151116007988	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1151116007989	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1151116007990	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1151116007991	[4Fe-4S] binding site [ion binding]; other site
1151116007992	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1151116007993	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1151116007994	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1151116007995	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1151116007996	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1151116007997	molybdopterin cofactor binding site; other site
1151116007998	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1151116007999	Uncharacterized bacterial subgroup of the Salmonella typhimurium Zn2+ transporter ZntB-like subfamily; Region: ZntB_u1; cd12834
1151116008000	Cl binding site [ion binding]; other site
1151116008001	oligomer interface [polypeptide binding]; other site
1151116008002	putative voltage-gated ClC-type chloride channel ClcB; Provisional; Region: PRK01862
1151116008003	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1151116008004	Cl- selectivity filter; other site
1151116008005	Cl- binding residues [ion binding]; other site
1151116008006	pore gating glutamate residue; other site
1151116008007	dimer interface [polypeptide binding]; other site
1151116008008	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1151116008009	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
1151116008010	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1151116008011	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116008012	non-specific DNA binding site [nucleotide binding]; other site
1151116008013	salt bridge; other site
1151116008014	sequence-specific DNA binding site [nucleotide binding]; other site
1151116008015	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116008016	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1151116008017	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1151116008018	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116008019	Walker A/P-loop; other site
1151116008020	ATP binding site [chemical binding]; other site
1151116008021	Q-loop/lid; other site
1151116008022	ABC transporter signature motif; other site
1151116008023	Walker B; other site
1151116008024	D-loop; other site
1151116008025	H-loop/switch region; other site
1151116008026	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116008027	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116008028	Walker A/P-loop; other site
1151116008029	ATP binding site [chemical binding]; other site
1151116008030	Q-loop/lid; other site
1151116008031	ABC transporter signature motif; other site
1151116008032	Walker B; other site
1151116008033	D-loop; other site
1151116008034	H-loop/switch region; other site
1151116008035	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1151116008036	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008037	dimer interface [polypeptide binding]; other site
1151116008038	conserved gate region; other site
1151116008039	putative PBP binding loops; other site
1151116008040	ABC-ATPase subunit interface; other site
1151116008041	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116008042	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008043	putative PBP binding loops; other site
1151116008044	dimer interface [polypeptide binding]; other site
1151116008045	ABC-ATPase subunit interface; other site
1151116008046	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116008047	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1151116008048	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
1151116008049	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1151116008050	putative active site pocket [active]
1151116008051	dimerization interface [polypeptide binding]; other site
1151116008052	putative catalytic residue [active]
1151116008053	cation transport regulator; Reviewed; Region: chaB; PRK09582
1151116008054	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1151116008055	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1151116008056	hypothetical protein; Provisional; Region: PRK10536
1151116008057	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1151116008058	AMIN domain; Region: AMIN; pfam11741
1151116008059	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1151116008060	active site
1151116008061	metal binding site [ion binding]; metal-binding site
1151116008062	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1151116008063	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1151116008064	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
1151116008065	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1151116008066	Imelysin; Region: Peptidase_M75; pfam09375
1151116008067	FTR1 family protein; Region: TIGR00145
1151116008068	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1151116008069	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1151116008070	Na binding site [ion binding]; other site
1151116008071	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1151116008072	Predicted transcriptional regulator [Transcription]; Region: COG3905
1151116008073	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1151116008074	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1151116008075	Glutamate binding site [chemical binding]; other site
1151116008076	NAD binding site [chemical binding]; other site
1151116008077	catalytic residues [active]
1151116008078	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1151116008079	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116008080	Walker A/P-loop; other site
1151116008081	ATP binding site [chemical binding]; other site
1151116008082	Q-loop/lid; other site
1151116008083	ABC transporter signature motif; other site
1151116008084	Walker B; other site
1151116008085	D-loop; other site
1151116008086	H-loop/switch region; other site
1151116008087	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116008088	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116008089	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008090	dimer interface [polypeptide binding]; other site
1151116008091	conserved gate region; other site
1151116008092	putative PBP binding loops; other site
1151116008093	ABC-ATPase subunit interface; other site
1151116008094	cystine transporter subunit; Provisional; Region: PRK11260
1151116008095	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116008096	substrate binding pocket [chemical binding]; other site
1151116008097	membrane-bound complex binding site; other site
1151116008098	hinge residues; other site
1151116008099	D-cysteine desulfhydrase; Validated; Region: PRK03910
1151116008100	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1151116008101	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116008102	catalytic residue [active]
1151116008103	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1151116008104	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1151116008105	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1151116008106	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1151116008107	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1151116008108	DNA binding residues [nucleotide binding]
1151116008109	flagellin; Validated; Region: PRK06819
1151116008110	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1151116008111	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1151116008112	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1151116008113	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1151116008114	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1151116008115	flagellar protein FliS; Validated; Region: fliS; PRK05685
1151116008116	Flagellar protein FliT; Region: FliT; cl05125
1151116008117	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116008118	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116008119	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1151116008120	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1151116008121	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1151116008122	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116008123	Coenzyme A binding pocket [chemical binding]; other site
1151116008124	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; cl01544
1151116008125	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1151116008126	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1151116008127	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1151116008128	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1151116008129	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1151116008130	FliG C-terminal domain; Region: FliG_C; pfam01706
1151116008131	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1151116008132	Flagellar assembly protein FliH; Region: FliH; pfam02108
1151116008133	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1151116008134	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1151116008135	Walker A motif/ATP binding site; other site
1151116008136	Walker B motif; other site
1151116008137	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1151116008138	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1151116008139	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
1151116008140	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1151116008141	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1151116008142	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1151116008143	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1151116008144	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1151116008145	Flagellar biosynthesis protein, FliO; Region: FliO; cl01247
1151116008146	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1151116008147	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1151116008148	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1151116008149	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1151116008150	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116008151	S-adenosylmethionine binding site [chemical binding]; other site
1151116008152	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1151116008153	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1151116008154	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008155	dimer interface [polypeptide binding]; other site
1151116008156	conserved gate region; other site
1151116008157	putative PBP binding loops; other site
1151116008158	ABC-ATPase subunit interface; other site
1151116008159	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008160	dimer interface [polypeptide binding]; other site
1151116008161	conserved gate region; other site
1151116008162	putative PBP binding loops; other site
1151116008163	ABC-ATPase subunit interface; other site
1151116008164	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1151116008165	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116008166	Walker A/P-loop; other site
1151116008167	ATP binding site [chemical binding]; other site
1151116008168	Q-loop/lid; other site
1151116008169	ABC transporter signature motif; other site
1151116008170	Walker B; other site
1151116008171	D-loop; other site
1151116008172	H-loop/switch region; other site
1151116008173	TOBE domain; Region: TOBE_2; pfam08402
1151116008174	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1151116008175	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1151116008176	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1151116008177	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1151116008178	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1151116008179	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1151116008180	dimer interface [polypeptide binding]; other site
1151116008181	FMN binding site [chemical binding]; other site
1151116008182	NADPH bind site [chemical binding]; other site
1151116008183	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1151116008184	GSH binding site [chemical binding]; other site
1151116008185	catalytic residues [active]
1151116008186	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1151116008187	putative transporter; Provisional; Region: PRK04972
1151116008188	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1151116008189	TrkA-C domain; Region: TrkA_C; pfam02080
1151116008190	TrkA-C domain; Region: TrkA_C; pfam02080
1151116008191	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1151116008192	Protein of unknown function (DUF796); Region: DUF796; cl01226
1151116008193	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
1151116008194	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1151116008195	active site
1151116008196	metal binding site [ion binding]; metal-binding site
1151116008197	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1151116008198	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1151116008199	trimer interface [polypeptide binding]; other site
1151116008200	eyelet of channel; other site
1151116008201	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1151116008202	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1151116008203	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1151116008204	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1151116008205	active site
1151116008206	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1151116008207	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1151116008208	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1151116008209	GlpM protein; Region: GlpM; pfam06942
1151116008210	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1151116008211	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1151116008212	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116008213	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116008214	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116008215	dimerization interface [polypeptide binding]; other site
1151116008216	hypothetical protein; Provisional; Region: PRK07079
1151116008217	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_2; cd05679
1151116008218	metal binding site [ion binding]; metal-binding site
1151116008219	putative dimer interface [polypeptide binding]; other site
1151116008220	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116008221	metabolite-proton symporter; Region: 2A0106; TIGR00883
1151116008222	putative substrate translocation pore; other site
1151116008223	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1151116008224	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1151116008225	Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305
1151116008226	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1151116008227	putative ligand binding site [chemical binding]; other site
1151116008228	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1151116008229	putative transporter; Provisional; Region: PRK11462
1151116008230	putative alpha-glucosidase; Provisional; Region: PRK10658
1151116008231	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1151116008232	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1151116008233	active site
1151116008234	homotrimer interface [polypeptide binding]; other site
1151116008235	catalytic site [active]
1151116008236	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1151116008237	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1151116008238	putative dimerization interface [polypeptide binding]; other site
1151116008239	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116008240	putative ligand binding site [chemical binding]; other site
1151116008241	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116008242	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116008243	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116008244	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116008245	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116008246	TM-ABC transporter signature motif; other site
1151116008247	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
1151116008248	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116008249	Walker A/P-loop; other site
1151116008250	ATP binding site [chemical binding]; other site
1151116008251	Q-loop/lid; other site
1151116008252	ABC transporter signature motif; other site
1151116008253	Walker B; other site
1151116008254	D-loop; other site
1151116008255	H-loop/switch region; other site
1151116008256	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116008257	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
1151116008258	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
1151116008259	putative ligand binding site [chemical binding]; other site
1151116008260	xylose isomerase; Provisional; Region: PRK05474
1151116008261	xylose isomerase; Region: xylose_isom_A; TIGR02630
1151116008262	xylulokinase; Provisional; Region: PRK15027
1151116008263	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1151116008264	N- and C-terminal domain interface [polypeptide binding]; other site
1151116008265	active site
1151116008266	MgATP binding site [chemical binding]; other site
1151116008267	catalytic site [active]
1151116008268	metal binding site [ion binding]; metal-binding site
1151116008269	xylulose binding site [chemical binding]; other site
1151116008270	homodimer interface [polypeptide binding]; other site
1151116008271	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1151116008272	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1151116008273	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1151116008274	putative active site; other site
1151116008275	catalytic residue [active]
1151116008276	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1151116008277	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1151116008278	ligand binding site [chemical binding]; other site
1151116008279	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116008280	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116008281	TM-ABC transporter signature motif; other site
1151116008282	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116008283	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116008284	TM-ABC transporter signature motif; other site
1151116008285	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1151116008286	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116008287	Walker A/P-loop; other site
1151116008288	ATP binding site [chemical binding]; other site
1151116008289	Q-loop/lid; other site
1151116008290	ABC transporter signature motif; other site
1151116008291	Walker B; other site
1151116008292	D-loop; other site
1151116008293	H-loop/switch region; other site
1151116008294	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116008295	transcriptional regulator LsrR; Provisional; Region: PRK15418
1151116008296	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1151116008297	non-specific DNA interactions [nucleotide binding]; other site
1151116008298	DNA binding site [nucleotide binding]
1151116008299	sequence specific DNA binding site [nucleotide binding]; other site
1151116008300	putative cAMP binding site [chemical binding]; other site
1151116008301	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1151116008302	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1151116008303	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1151116008304	putative N- and C-terminal domain interface [polypeptide binding]; other site
1151116008305	putative active site [active]
1151116008306	putative MgATP binding site [chemical binding]; other site
1151116008307	catalytic site [active]
1151116008308	metal binding site [ion binding]; metal-binding site
1151116008309	putative carbohydrate binding site [chemical binding]; other site
1151116008310	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
1151116008311	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1151116008312	active site
1151116008313	intersubunit interactions; other site
1151116008314	catalytic residue [active]
1151116008315	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1151116008316	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116008317	FeS/SAM binding site; other site
1151116008318	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1151116008319	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1151116008320	dimer interface [polypeptide binding]; other site
1151116008321	active site
1151116008322	glycine loop; other site
1151116008323	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1151116008324	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1151116008325	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1151116008326	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1151116008327	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1151116008328	intersubunit interface [polypeptide binding]; other site
1151116008329	active site
1151116008330	Zn2+ binding site [ion binding]; other site
1151116008331	lipoprotein; Provisional; Region: PRK10540
1151116008332	translation initiation factor Sui1; Validated; Region: PRK06824
1151116008333	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1151116008334	putative rRNA binding site [nucleotide binding]; other site
1151116008335	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1151116008336	active site
1151116008337	dimer interface [polypeptide binding]; other site
1151116008338	tetratricopeptide repeat protein; Provisional; Region: PRK11788
1151116008339	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1151116008340	TPR motif; other site
1151116008341	binding surface
1151116008342	Predicted membrane protein [Function unknown]; Region: COG3771
1151116008343	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1151116008344	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1151116008345	active site
1151116008346	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1151116008347	dimerization interface [polypeptide binding]; other site
1151116008348	active site
1151116008349	aconitate hydratase; Validated; Region: PRK09277
1151116008350	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1151116008351	substrate binding site [chemical binding]; other site
1151116008352	ligand binding site [chemical binding]; other site
1151116008353	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1151116008354	substrate binding site [chemical binding]; other site
1151116008355	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1151116008356	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116008357	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1151116008358	substrate binding site [chemical binding]; other site
1151116008359	putative dimerization interface [polypeptide binding]; other site
1151116008360	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1151116008361	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1151116008362	active site
1151116008363	interdomain interaction site; other site
1151116008364	putative metal-binding site [ion binding]; other site
1151116008365	nucleotide binding site [chemical binding]; other site
1151116008366	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1151116008367	domain I; other site
1151116008368	DNA binding groove [nucleotide binding]
1151116008369	phosphate binding site [ion binding]; other site
1151116008370	domain II; other site
1151116008371	domain III; other site
1151116008372	nucleotide binding site [chemical binding]; other site
1151116008373	catalytic site [active]
1151116008374	domain IV; other site
1151116008375	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1151116008376	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1151116008377	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1151116008378	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1151116008379	hypothetical protein; Provisional; Region: PRK11037
1151116008380	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1151116008381	putative inner membrane peptidase; Provisional; Region: PRK11778
1151116008382	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1151116008383	tandem repeat interface [polypeptide binding]; other site
1151116008384	oligomer interface [polypeptide binding]; other site
1151116008385	active site residues [active]
1151116008386	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1151116008387	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116008388	NAD(P) binding site [chemical binding]; other site
1151116008389	active site
1151116008390	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1151116008391	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
1151116008392	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1151116008393	homodimer interface [polypeptide binding]; other site
1151116008394	Walker A motif; other site
1151116008395	ATP binding site [chemical binding]; other site
1151116008396	hydroxycobalamin binding site [chemical binding]; other site
1151116008397	Walker B motif; other site
1151116008398	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1151116008399	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1151116008400	putative dimer interface [polypeptide binding]; other site
1151116008401	active site pocket [active]
1151116008402	putative cataytic base [active]
1151116008403	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1151116008404	catalytic core [active]
1151116008405	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1151116008406	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1151116008407	homotrimer interface [polypeptide binding]; other site
1151116008408	Walker A motif; other site
1151116008409	GTP binding site [chemical binding]; other site
1151116008410	Walker B motif; other site
1151116008411	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1151116008412	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1151116008413	RNA binding surface [nucleotide binding]; other site
1151116008414	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1151116008415	probable active site [active]
1151116008416	hypothetical protein; Provisional; Region: PRK11630
1151116008417	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1151116008418	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1151116008419	active site
1151116008420	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1151116008421	anthranilate synthase component I; Provisional; Region: PRK13564
1151116008422	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1151116008423	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1151116008424	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1151116008425	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1151116008426	glutamine binding [chemical binding]; other site
1151116008427	catalytic triad [active]
1151116008428	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1151116008429	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1151116008430	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1151116008431	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1151116008432	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1151116008433	active site
1151116008434	ribulose/triose binding site [chemical binding]; other site
1151116008435	phosphate binding site [ion binding]; other site
1151116008436	substrate (anthranilate) binding pocket [chemical binding]; other site
1151116008437	product (indole) binding pocket [chemical binding]; other site
1151116008438	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1151116008439	active site
1151116008440	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1151116008441	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1151116008442	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116008443	catalytic residue [active]
1151116008444	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1151116008445	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1151116008446	substrate binding site [chemical binding]; other site
1151116008447	active site
1151116008448	catalytic residues [active]
1151116008449	heterodimer interface [polypeptide binding]; other site
1151116008450	BON domain; Region: BON; pfam04972
1151116008451	outer membrane protein W; Provisional; Region: PRK10959
1151116008452	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1151116008453	hypothetical protein; Provisional; Region: PRK02868
1151116008454	intracellular septation protein A; Reviewed; Region: PRK00259
1151116008455	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1151116008456	transport protein TonB; Provisional; Region: PRK10819
1151116008457	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1151116008458	YciI-like protein; Reviewed; Region: PRK11370
1151116008459	Transcription factor zinc-finger; Region: zf-TFIIB; cl01565
1151116008460	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1151116008461	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1151116008462	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1151116008463	putative active site [active]
1151116008464	catalytic site [active]
1151116008465	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1151116008466	putative active site [active]
1151116008467	catalytic site [active]
1151116008468	dsDNA-mimic protein; Reviewed; Region: PRK05094
1151116008469	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1151116008470	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116008471	Walker A/P-loop; other site
1151116008472	ATP binding site [chemical binding]; other site
1151116008473	Q-loop/lid; other site
1151116008474	ABC transporter signature motif; other site
1151116008475	Walker B; other site
1151116008476	D-loop; other site
1151116008477	H-loop/switch region; other site
1151116008478	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1151116008479	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1151116008480	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116008481	Walker A/P-loop; other site
1151116008482	ATP binding site [chemical binding]; other site
1151116008483	Q-loop/lid; other site
1151116008484	ABC transporter signature motif; other site
1151116008485	Walker B; other site
1151116008486	D-loop; other site
1151116008487	H-loop/switch region; other site
1151116008488	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116008489	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1151116008490	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1151116008491	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008492	dimer interface [polypeptide binding]; other site
1151116008493	conserved gate region; other site
1151116008494	putative PBP binding loops; other site
1151116008495	ABC-ATPase subunit interface; other site
1151116008496	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1151116008497	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008498	dimer interface [polypeptide binding]; other site
1151116008499	conserved gate region; other site
1151116008500	putative PBP binding loops; other site
1151116008501	ABC-ATPase subunit interface; other site
1151116008502	potential frameshift: common BLAST hit: gi|322833347|ref|YP_004213374.1| family 5 extracellular solute-binding protein
1151116008503	hypothetical protein; Provisional; Region: PRK11111
1151116008504	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1151116008505	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1151116008506	putative catalytic cysteine [active]
1151116008507	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1151116008508	putative active site [active]
1151116008509	metal binding site [ion binding]; metal-binding site
1151116008510	thymidine kinase; Provisional; Region: PRK04296
1151116008511	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1151116008512	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1151116008513	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1151116008514	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
1151116008515	putative NAD(P) binding site [chemical binding]; other site
1151116008516	active site
1151116008517	putative substrate binding site [chemical binding]; other site
1151116008518	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1151116008519	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1151116008520	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1151116008521	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1151116008522	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116008523	active site
1151116008524	response regulator of RpoS; Provisional; Region: PRK10693
1151116008525	phosphorylation site [posttranslational modification]
1151116008526	intermolecular recognition site; other site
1151116008527	dimerization interface [polypeptide binding]; other site
1151116008528	hypothetical protein; Provisional; Region: PRK10279
1151116008529	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1151116008530	active site
1151116008531	nucleophile elbow; other site
1151116008532	hypothetical protein; Provisional; Region: PRK01617
1151116008533	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1151116008534	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1151116008535	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1151116008536	putative active site [active]
1151116008537	putative substrate binding site [chemical binding]; other site
1151116008538	putative cosubstrate binding site; other site
1151116008539	catalytic site [active]
1151116008540	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1151116008541	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116008542	Walker A/P-loop; other site
1151116008543	ATP binding site [chemical binding]; other site
1151116008544	Q-loop/lid; other site
1151116008545	ABC transporter signature motif; other site
1151116008546	Walker B; other site
1151116008547	D-loop; other site
1151116008548	H-loop/switch region; other site
1151116008549	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116008550	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116008551	Walker A/P-loop; other site
1151116008552	ATP binding site [chemical binding]; other site
1151116008553	Q-loop/lid; other site
1151116008554	ABC transporter signature motif; other site
1151116008555	Walker B; other site
1151116008556	D-loop; other site
1151116008557	H-loop/switch region; other site
1151116008558	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1151116008559	Uncharacterized conserved protein [Function unknown]; Region: COG5476
1151116008560	Protein of unknown function (DUF1485); Region: DUF1485; pfam07364
1151116008561	MlrC C-terminus; Region: MlrC_C; pfam07171
1151116008562	MarR family; Region: MarR_2; pfam12802
1151116008563	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
1151116008564	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116008565	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1151116008566	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1151116008567	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116008568	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116008569	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008570	dimer interface [polypeptide binding]; other site
1151116008571	conserved gate region; other site
1151116008572	putative PBP binding loops; other site
1151116008573	ABC-ATPase subunit interface; other site
1151116008574	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116008575	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008576	dimer interface [polypeptide binding]; other site
1151116008577	conserved gate region; other site
1151116008578	putative PBP binding loops; other site
1151116008579	ABC-ATPase subunit interface; other site
1151116008580	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1151116008581	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116008582	nucleotide binding site [chemical binding]; other site
1151116008583	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1151116008584	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1151116008585	diaminopimelate epimerase; Provisional; Region: PRK13577
1151116008586	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1151116008587	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1151116008588	benzoate transport; Region: 2A0115; TIGR00895
1151116008589	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116008590	putative substrate translocation pore; other site
1151116008591	protocatechuate 4,5-dioxygenase; Provisional; Region: PRK13367
1151116008592	The N-terminal domain of the Class III extradiol dioxygenase, Gallate Dioxygenase, which catalyzes the oxidization and subsequent ring-opening of gallate; Region: Gallate_Doxase_N; cd07950
1151116008593	putative active site [active]
1151116008594	Fe(II) binding site [ion binding]; other site
1151116008595	putative dimer interface [polypeptide binding]; other site
1151116008596	The C-terminal domain of Gallate Dioxygenase, which catalyzes the oxidization and subsequent ring-opening of gallate; Region: Gallate_dioxygenase_C; cd07923
1151116008597	putative dimer interface [polypeptide binding]; other site
1151116008598	putative N- and C-terminal domain interface [polypeptide binding]; other site
1151116008599	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
1151116008600	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1151116008601	active site
1151116008602	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1151116008603	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1151116008604	trimer interface [polypeptide binding]; other site
1151116008605	active site
1151116008606	dimer interface [polypeptide binding]; other site
1151116008607	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1151116008608	O-Antigen ligase; Region: Wzy_C; pfam04932
1151116008609	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
1151116008610	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1151116008611	putative ADP-binding pocket [chemical binding]; other site
1151116008612	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116008613	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116008614	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1151116008615	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116008616	The C-terminal substrate binding domain of galactose-binding protein regulator contains the type 2 periplasmic binding fold; Region: PBP2_GbpR; cd08435
1151116008617	putative dimerization interface [polypeptide binding]; other site
1151116008618	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
1151116008619	hypothetical protein; Provisional; Region: PRK09262
1151116008620	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2828
1151116008621	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1151116008622	Domain of unknown function (DUF1932); Region: DUF1932; pfam09130
1151116008623	potential frameshift: common BLAST hit: gi|322833378|ref|YP_004213405.1| oligopeptide/dipeptide ABC transporter ATPase
1151116008624	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1151116008625	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116008626	Walker A/P-loop; other site
1151116008627	ATP binding site [chemical binding]; other site
1151116008628	Q-loop/lid; other site
1151116008629	ABC transporter signature motif; other site
1151116008630	Walker B; other site
1151116008631	D-loop; other site
1151116008632	H-loop/switch region; other site
1151116008633	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116008634	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
1151116008635	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1151116008636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008637	dimer interface [polypeptide binding]; other site
1151116008638	conserved gate region; other site
1151116008639	putative PBP binding loops; other site
1151116008640	ABC-ATPase subunit interface; other site
1151116008641	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116008642	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008643	dimer interface [polypeptide binding]; other site
1151116008644	conserved gate region; other site
1151116008645	putative PBP binding loops; other site
1151116008646	ABC-ATPase subunit interface; other site
1151116008647	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116008648	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1151116008649	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
1151116008650	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1151116008651	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116008652	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1151116008653	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1151116008654	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1151116008655	Ca binding site [ion binding]; other site
1151116008656	active site
1151116008657	catalytic site [active]
1151116008658	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1151116008659	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1151116008660	Ca binding site [ion binding]; other site
1151116008661	active site
1151116008662	catalytic site [active]
1151116008663	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1151116008664	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1151116008665	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1151116008666	Walker A/P-loop; other site
1151116008667	ATP binding site [chemical binding]; other site
1151116008668	Q-loop/lid; other site
1151116008669	ABC transporter signature motif; other site
1151116008670	Walker B; other site
1151116008671	D-loop; other site
1151116008672	H-loop/switch region; other site
1151116008673	TOBE domain; Region: TOBE_2; pfam08402
1151116008674	alpha-galactosidase; Provisional; Region: PRK15076
1151116008675	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1151116008676	NAD(P) binding site [chemical binding]; other site
1151116008677	LDH/MDH dimer interface [polypeptide binding]; other site
1151116008678	substrate binding site [chemical binding]; other site
1151116008679	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116008680	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008681	dimer interface [polypeptide binding]; other site
1151116008682	conserved gate region; other site
1151116008683	putative PBP binding loops; other site
1151116008684	ABC-ATPase subunit interface; other site
1151116008685	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008686	dimer interface [polypeptide binding]; other site
1151116008687	conserved gate region; other site
1151116008688	putative PBP binding loops; other site
1151116008689	ABC-ATPase subunit interface; other site
1151116008690	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1151116008691	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1151116008692	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116008693	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116008694	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1151116008695	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
1151116008696	active site turn [active]
1151116008697	phosphorylation site [posttranslational modification]
1151116008698	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1151116008699	Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase; Region: HPPR; cd12156
1151116008700	putative ligand binding site [chemical binding]; other site
1151116008701	NAD binding site [chemical binding]; other site
1151116008702	catalytic site [active]
1151116008703	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1151116008704	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116008705	putative substrate translocation pore; other site
1151116008706	galactonate dehydratase; Provisional; Region: PRK14017
1151116008707	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1151116008708	putative active site pocket [active]
1151116008709	putative metal binding site [ion binding]; other site
1151116008710	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1151116008711	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1151116008712	active site
1151116008713	intersubunit interface [polypeptide binding]; other site
1151116008714	catalytic residue [active]
1151116008715	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1151116008716	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1151116008717	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116008718	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116008719	DNA-binding site [nucleotide binding]; DNA binding site
1151116008720	FCD domain; Region: FCD; pfam07729
1151116008721	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116008722	Coenzyme A binding pocket [chemical binding]; other site
1151116008723	potential frameshift: common BLAST hit: gi|322833401|ref|YP_004213428.1| transposase IS116/IS110/IS902 family protein
1151116008724	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1151116008725	active site
1151116008726	Int/Topo IB signature motif; other site
1151116008727	DNA binding site [nucleotide binding]
1151116008728	LysE type translocator; Region: LysE; cl00565
1151116008729	GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs; Region: GIY-YIG_COG3680; cd10440
1151116008730	GIY-YIG motif/motif A; other site
1151116008731	putative active site [active]
1151116008732	putative metal binding site [ion binding]; other site
1151116008733	N-acetyltransferase; Region: Acetyltransf_2; pfam00797
1151116008734	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1151116008735	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116008736	DNA-binding site [nucleotide binding]; DNA binding site
1151116008737	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116008738	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116008739	homodimer interface [polypeptide binding]; other site
1151116008740	catalytic residue [active]
1151116008741	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1151116008742	EamA-like transporter family; Region: EamA; pfam00892
1151116008743	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116008744	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116008745	substrate binding pocket [chemical binding]; other site
1151116008746	membrane-bound complex binding site; other site
1151116008747	hinge residues; other site
1151116008748	Allophanate hydrolase subunit 1; Region: AHS1; smart00796
1151116008749	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
1151116008750	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1151116008751	aspartate aminotransferase; Provisional; Region: PRK05764
1151116008752	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116008753	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116008754	homodimer interface [polypeptide binding]; other site
1151116008755	catalytic residue [active]
1151116008756	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
1151116008757	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116008758	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1151116008759	putative dimerization interface [polypeptide binding]; other site
1151116008760	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1151116008761	carboxyltransferase (CT) interaction site; other site
1151116008762	biotinylation site [posttranslational modification]; other site
1151116008763	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
1151116008764	putative active site [active]
1151116008765	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1151116008766	classical (c) SDRs; Region: SDR_c; cd05233
1151116008767	NAD(P) binding site [chemical binding]; other site
1151116008768	active site
1151116008769	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008770	dimer interface [polypeptide binding]; other site
1151116008771	conserved gate region; other site
1151116008772	putative PBP binding loops; other site
1151116008773	ABC-ATPase subunit interface; other site
1151116008774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008775	dimer interface [polypeptide binding]; other site
1151116008776	conserved gate region; other site
1151116008777	putative PBP binding loops; other site
1151116008778	ABC-ATPase subunit interface; other site
1151116008779	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116008780	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116008781	Walker A/P-loop; other site
1151116008782	ATP binding site [chemical binding]; other site
1151116008783	Q-loop/lid; other site
1151116008784	ABC transporter signature motif; other site
1151116008785	Walker B; other site
1151116008786	D-loop; other site
1151116008787	H-loop/switch region; other site
1151116008788	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1151116008789	NmrA-like family; Region: NmrA; pfam05368
1151116008790	NmrA (a transcriptional regulator) and HSCARG (an NADPH sensor) like proteins, atypical (a) SDRs; Region: NmrA_like_SDR_a; cd05251
1151116008791	NADP binding site [chemical binding]; other site
1151116008792	active site
1151116008793	regulatory binding site [polypeptide binding]; other site
1151116008794	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1151116008795	LysR family transcriptional regulator; Provisional; Region: PRK14997
1151116008796	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116008797	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116008798	putative effector binding pocket; other site
1151116008799	dimerization interface [polypeptide binding]; other site
1151116008800	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1151116008801	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1151116008802	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008803	dimer interface [polypeptide binding]; other site
1151116008804	conserved gate region; other site
1151116008805	ABC-ATPase subunit interface; other site
1151116008806	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1151116008807	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1151116008808	Walker A/P-loop; other site
1151116008809	ATP binding site [chemical binding]; other site
1151116008810	Q-loop/lid; other site
1151116008811	ABC transporter signature motif; other site
1151116008812	Walker B; other site
1151116008813	D-loop; other site
1151116008814	H-loop/switch region; other site
1151116008815	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1151116008816	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1151116008817	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1151116008818	potential frameshift: common BLAST hit: gi|322833431|ref|YP_004213458.1| Phosphatidylglycerol--membrane-oligosaccharide
1151116008819	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1151116008820	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1151116008821	Walker A/P-loop; other site
1151116008822	ATP binding site [chemical binding]; other site
1151116008823	Q-loop/lid; other site
1151116008824	ABC transporter signature motif; other site
1151116008825	Walker B; other site
1151116008826	D-loop; other site
1151116008827	H-loop/switch region; other site
1151116008828	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1151116008829	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1151116008830	Walker A/P-loop; other site
1151116008831	ATP binding site [chemical binding]; other site
1151116008832	Q-loop/lid; other site
1151116008833	ABC transporter signature motif; other site
1151116008834	Walker B; other site
1151116008835	D-loop; other site
1151116008836	H-loop/switch region; other site
1151116008837	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1151116008838	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1151116008839	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1151116008840	TM-ABC transporter signature motif; other site
1151116008841	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116008842	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1151116008843	TM-ABC transporter signature motif; other site
1151116008844	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1151116008845	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1151116008846	dimerization interface [polypeptide binding]; other site
1151116008847	ligand binding site [chemical binding]; other site
1151116008848	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1151116008849	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1151116008850	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116008851	dimerization interface [polypeptide binding]; other site
1151116008852	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116008853	dimer interface [polypeptide binding]; other site
1151116008854	putative CheW interface [polypeptide binding]; other site
1151116008855	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1151116008856	dimer interface [polypeptide binding]; other site
1151116008857	active site
1151116008858	Schiff base residues; other site
1151116008859	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1151116008860	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
1151116008861	putative active site [active]
1151116008862	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1151116008863	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
1151116008864	Walker A/P-loop; other site
1151116008865	ATP binding site [chemical binding]; other site
1151116008866	Q-loop/lid; other site
1151116008867	ABC transporter signature motif; other site
1151116008868	Walker B; other site
1151116008869	D-loop; other site
1151116008870	H-loop/switch region; other site
1151116008871	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1151116008872	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116008873	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116008874	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1151116008875	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1151116008876	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1151116008877	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1151116008878	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
1151116008879	This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990
1151116008880	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
1151116008881	hypothetical protein; Provisional; Region: PRK05415
1151116008882	Domain of unknown function (DUF697); Region: DUF697; cl12064
1151116008883	Predicted ATPase [General function prediction only]; Region: COG3106
1151116008884	Phage shock protein PspD (Phageshock_PspD); Region: Phageshock_PspD; cl11512
1151116008885	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1151116008886	phage shock protein C; Region: phageshock_pspC; TIGR02978
1151116008887	phage shock protein B; Provisional; Region: pspB; PRK09458
1151116008888	phage shock protein PspA; Provisional; Region: PRK10698
1151116008889	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1151116008890	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116008891	Walker A motif; other site
1151116008892	ATP binding site [chemical binding]; other site
1151116008893	Walker B motif; other site
1151116008894	arginine finger; other site
1151116008895	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1151116008896	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1151116008897	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1151116008898	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1151116008899	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1151116008900	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1151116008901	peptide binding site [polypeptide binding]; other site
1151116008902	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1151116008903	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008904	dimer interface [polypeptide binding]; other site
1151116008905	conserved gate region; other site
1151116008906	putative PBP binding loops; other site
1151116008907	ABC-ATPase subunit interface; other site
1151116008908	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1151116008909	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116008910	dimer interface [polypeptide binding]; other site
1151116008911	conserved gate region; other site
1151116008912	putative PBP binding loops; other site
1151116008913	ABC-ATPase subunit interface; other site
1151116008914	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1151116008915	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116008916	Walker A/P-loop; other site
1151116008917	ATP binding site [chemical binding]; other site
1151116008918	Q-loop/lid; other site
1151116008919	ABC transporter signature motif; other site
1151116008920	Walker B; other site
1151116008921	D-loop; other site
1151116008922	H-loop/switch region; other site
1151116008923	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116008924	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1151116008925	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116008926	Walker A/P-loop; other site
1151116008927	ATP binding site [chemical binding]; other site
1151116008928	Q-loop/lid; other site
1151116008929	ABC transporter signature motif; other site
1151116008930	Walker B; other site
1151116008931	D-loop; other site
1151116008932	H-loop/switch region; other site
1151116008933	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116008934	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950; cl17731
1151116008935	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
1151116008936	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
1151116008937	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1151116008938	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116008939	putative substrate translocation pore; other site
1151116008940	POT family; Region: PTR2; pfam00854
1151116008941	putative acyl transferase; Provisional; Region: PRK10191
1151116008942	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1151116008943	trimer interface [polypeptide binding]; other site
1151116008944	active site
1151116008945	substrate binding site [chemical binding]; other site
1151116008946	CoA binding site [chemical binding]; other site
1151116008947	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1151116008948	GAF domain; Region: GAF; pfam01590
1151116008949	PAS domain S-box; Region: sensory_box; TIGR00229
1151116008950	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116008951	putative active site [active]
1151116008952	heme pocket [chemical binding]; other site
1151116008953	PAS domain S-box; Region: sensory_box; TIGR00229
1151116008954	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116008955	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116008956	metal binding site [ion binding]; metal-binding site
1151116008957	active site
1151116008958	I-site; other site
1151116008959	Helix-turn-helix domain; Region: HTH_18; pfam12833
1151116008960	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116008961	PAS domain; Region: PAS_9; pfam13426
1151116008962	putative active site [active]
1151116008963	heme pocket [chemical binding]; other site
1151116008964	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116008965	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116008966	metal binding site [ion binding]; metal-binding site
1151116008967	active site
1151116008968	I-site; other site
1151116008969	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116008970	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1151116008971	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1151116008972	dimer interface [polypeptide binding]; other site
1151116008973	active site
1151116008974	catalytic residue [active]
1151116008975	glutathionine S-transferase; Provisional; Region: PRK10542
1151116008976	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1151116008977	C-terminal domain interface [polypeptide binding]; other site
1151116008978	GSH binding site (G-site) [chemical binding]; other site
1151116008979	dimer interface [polypeptide binding]; other site
1151116008980	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1151116008981	dimer interface [polypeptide binding]; other site
1151116008982	N-terminal domain interface [polypeptide binding]; other site
1151116008983	substrate binding pocket (H-site) [chemical binding]; other site
1151116008984	pyridoxamine kinase; Validated; Region: PRK05756
1151116008985	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1151116008986	dimer interface [polypeptide binding]; other site
1151116008987	pyridoxal binding site [chemical binding]; other site
1151116008988	ATP binding site [chemical binding]; other site
1151116008989	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1151116008990	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1151116008991	active site
1151116008992	HIGH motif; other site
1151116008993	dimer interface [polypeptide binding]; other site
1151116008994	KMSKS motif; other site
1151116008995	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1151116008996	RNA binding surface [nucleotide binding]; other site
1151116008997	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1151116008998	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1151116008999	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1151116009000	lysozyme inhibitor; Provisional; Region: PRK11372
1151116009001	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1151116009002	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1151116009003	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1151116009004	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
1151116009005	transcriptional regulator SlyA; Provisional; Region: PRK03573
1151116009006	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1151116009007	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1151116009008	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1151116009009	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116009010	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116009011	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1151116009012	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1151116009013	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116009014	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116009015	active site
1151116009016	catalytic tetrad [active]
1151116009017	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1151116009018	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1151116009019	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1151116009020	FMN binding site [chemical binding]; other site
1151116009021	active site
1151116009022	substrate binding site [chemical binding]; other site
1151116009023	catalytic residue [active]
1151116009024	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1151116009025	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1151116009026	dimer interface [polypeptide binding]; other site
1151116009027	active site
1151116009028	metal binding site [ion binding]; metal-binding site
1151116009029	glutathione binding site [chemical binding]; other site
1151116009030	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1151116009031	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1151116009032	dimer interface [polypeptide binding]; other site
1151116009033	catalytic site [active]
1151116009034	putative active site [active]
1151116009035	putative substrate binding site [chemical binding]; other site
1151116009036	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1151116009037	putative GSH binding site [chemical binding]; other site
1151116009038	catalytic residues [active]
1151116009039	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1151116009040	NlpC/P60 family; Region: NLPC_P60; pfam00877
1151116009041	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1151116009042	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116009043	DNA binding site [nucleotide binding]
1151116009044	domain linker motif; other site
1151116009045	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1151116009046	dimerization interface [polypeptide binding]; other site
1151116009047	ligand binding site [chemical binding]; other site
1151116009048	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1151116009049	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116009050	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116009051	dimerization interface [polypeptide binding]; other site
1151116009052	putative transporter; Provisional; Region: PRK11043
1151116009053	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116009054	putative substrate translocation pore; other site
1151116009055	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1151116009056	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1151116009057	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116009058	S-adenosylmethionine binding site [chemical binding]; other site
1151116009059	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1151116009060	Lumazine binding domain; Region: Lum_binding; pfam00677
1151116009061	Lumazine binding domain; Region: Lum_binding; pfam00677
1151116009062	multidrug efflux protein; Reviewed; Region: PRK01766
1151116009063	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1151116009064	cation binding site [ion binding]; other site
1151116009065	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1151116009066	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1151116009067	pyruvate kinase; Provisional; Region: PTZ00300
1151116009068	domain interfaces; other site
1151116009069	active site
1151116009070	murein lipoprotein; Provisional; Region: PRK15396
1151116009071	L,D-transpeptidase; Provisional; Region: PRK10190
1151116009072	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1151116009073	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1151116009074	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1151116009075	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1151116009076	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1151116009077	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116009078	catalytic residue [active]
1151116009079	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1151116009080	FeS assembly protein SufD; Region: sufD; TIGR01981
1151116009081	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1151116009082	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1151116009083	Walker A/P-loop; other site
1151116009084	ATP binding site [chemical binding]; other site
1151116009085	Q-loop/lid; other site
1151116009086	ABC transporter signature motif; other site
1151116009087	Walker B; other site
1151116009088	D-loop; other site
1151116009089	H-loop/switch region; other site
1151116009090	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1151116009091	putative ABC transporter; Region: ycf24; CHL00085
1151116009092	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1151116009093	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1151116009094	CoenzymeA binding site [chemical binding]; other site
1151116009095	subunit interaction site [polypeptide binding]; other site
1151116009096	PHB binding site; other site
1151116009097	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1151116009098	FAD binding domain; Region: FAD_binding_4; pfam01565
1151116009099	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1151116009100	putative inner membrane protein; Provisional; Region: PRK10983
1151116009101	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1151116009102	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1151116009103	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1151116009104	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1151116009105	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1151116009106	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1151116009107	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1151116009108	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1151116009109	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
1151116009110	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1151116009111	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
1151116009112	ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ChuT; COG4558
1151116009113	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
1151116009114	putative hemin binding site; other site
1151116009115	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1151116009116	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116009117	ABC-ATPase subunit  interface; other site
1151116009118	dimer interface [polypeptide binding]; other site
1151116009119	putative PBP binding regions; other site
1151116009120	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
1151116009121	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1151116009122	Walker A/P-loop; other site
1151116009123	ATP binding site [chemical binding]; other site
1151116009124	Q-loop/lid; other site
1151116009125	ABC transporter signature motif; other site
1151116009126	Walker B; other site
1151116009127	D-loop; other site
1151116009128	H-loop/switch region; other site
1151116009129	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1151116009130	hypothetical protein; Validated; Region: PRK00029
1151116009131	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1151116009132	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1151116009133	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1151116009134	Uncharacterized protein conserved in bacteria (DUF2188); Region: DUF2188; pfam09954
1151116009135	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116009136	S-adenosylmethionine binding site [chemical binding]; other site
1151116009137	Predicted P-loop ATPase [General function prediction only]; Region: COG4928
1151116009138	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
1151116009139	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
1151116009140	GIY-YIG motif/motif A; other site
1151116009141	active site
1151116009142	catalytic site [active]
1151116009143	metal binding site [ion binding]; metal-binding site
1151116009144	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1151116009145	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1151116009146	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1151116009147	Interdomain contacts; other site
1151116009148	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1151116009149	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
1151116009150	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
1151116009151	Phage capsid family; Region: Phage_capsid; pfam05065
1151116009152	Phage portal protein, lambda family; Region: Phage_portal_2; pfam05136
1151116009153	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1151116009154	Phage terminase large subunit (GpA); Region: Terminase_GpA; pfam05876
1151116009155	Phage DNA packaging protein Nu1; Region: Phage_Nu1; cl01720
1151116009156	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_1; cd10446
1151116009157	GIY-YIG motif/motif A; other site
1151116009158	putative active site [active]
1151116009159	putative metal binding site [ion binding]; other site
1151116009160	NUMOD4 motif; Region: NUMOD4; pfam07463
1151116009161	HNH endonuclease; Region: HNH_3; pfam13392
1151116009162	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1151116009163	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1151116009164	catalytic residues [active]
1151116009165	catalytic nucleophile [active]
1151116009166	Recombinase; Region: Recombinase; pfam07508
1151116009167	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1151116009168	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1151116009169	NlpC/P60 family; Region: NLPC_P60; pfam00877
1151116009170	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1151116009171	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1151116009172	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1151116009173	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1151116009174	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1151116009175	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1151116009176	putative active site [active]
1151116009177	putative catalytic site [active]
1151116009178	putative Zn binding site [ion binding]; other site
1151116009179	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1151116009180	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1151116009181	active site
1151116009182	substrate binding site [chemical binding]; other site
1151116009183	cosubstrate binding site; other site
1151116009184	catalytic site [active]
1151116009185	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1151116009186	active site
1151116009187	hexamer interface [polypeptide binding]; other site
1151116009188	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1151116009189	NAD binding site [chemical binding]; other site
1151116009190	substrate binding site [chemical binding]; other site
1151116009191	active site
1151116009192	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1151116009193	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1151116009194	Ligand binding site; other site
1151116009195	Putative Catalytic site; other site
1151116009196	DXD motif; other site
1151116009197	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1151116009198	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1151116009199	inhibitor-cofactor binding pocket; inhibition site
1151116009200	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116009201	catalytic residue [active]
1151116009202	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
1151116009203	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1151116009204	Walker A/P-loop; other site
1151116009205	ATP binding site [chemical binding]; other site
1151116009206	Q-loop/lid; other site
1151116009207	ABC transporter signature motif; other site
1151116009208	Walker B; other site
1151116009209	D-loop; other site
1151116009210	H-loop/switch region; other site
1151116009211	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1151116009212	catalytic residues [active]
1151116009213	dimer interface [polypeptide binding]; other site
1151116009214	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1151116009215	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116009216	ABC-ATPase subunit  interface; other site
1151116009217	dimer interface [polypeptide binding]; other site
1151116009218	putative PBP binding regions; other site
1151116009219	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1151116009220	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1151116009221	IHF dimer interface [polypeptide binding]; other site
1151116009222	IHF - DNA interface [nucleotide binding]; other site
1151116009223	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1151116009224	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1151116009225	putative tRNA-binding site [nucleotide binding]; other site
1151116009226	B3/4 domain; Region: B3_4; pfam03483
1151116009227	tRNA synthetase B5 domain; Region: B5; smart00874
1151116009228	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1151116009229	dimer interface [polypeptide binding]; other site
1151116009230	motif 1; other site
1151116009231	motif 3; other site
1151116009232	motif 2; other site
1151116009233	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1151116009234	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1151116009235	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1151116009236	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1151116009237	dimer interface [polypeptide binding]; other site
1151116009238	motif 1; other site
1151116009239	active site
1151116009240	motif 2; other site
1151116009241	motif 3; other site
1151116009242	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1151116009243	23S rRNA binding site [nucleotide binding]; other site
1151116009244	L21 binding site [polypeptide binding]; other site
1151116009245	L13 binding site [polypeptide binding]; other site
1151116009246	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1151116009247	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1151116009248	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1151116009249	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1151116009250	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1151116009251	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1151116009252	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1151116009253	active site
1151116009254	dimer interface [polypeptide binding]; other site
1151116009255	motif 1; other site
1151116009256	motif 2; other site
1151116009257	motif 3; other site
1151116009258	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1151116009259	anticodon binding site; other site
1151116009260	inner membrane protein; Provisional; Region: PRK10995
1151116009261	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1151116009262	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116009263	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116009264	catalytic residue [active]
1151116009265	Phosphotransferase enzyme family; Region: APH; pfam01636
1151116009266	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1151116009267	active site
1151116009268	ATP binding site [chemical binding]; other site
1151116009269	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1151116009270	YniB-like protein; Region: YniB; pfam14002
1151116009271	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1151116009272	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1151116009273	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116009274	motif II; other site
1151116009275	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1151116009276	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1151116009277	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1151116009278	NADP binding site [chemical binding]; other site
1151116009279	homodimer interface [polypeptide binding]; other site
1151116009280	active site
1151116009281	inner membrane protein; Provisional; Region: PRK11648
1151116009282	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1151116009283	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1151116009284	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1151116009285	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116009286	dimerization interface [polypeptide binding]; other site
1151116009287	putative Zn2+ binding site [ion binding]; other site
1151116009288	putative DNA binding site [nucleotide binding]; other site
1151116009289	Bacterial transcriptional regulator; Region: IclR; pfam01614
1151116009290	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1151116009291	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116009292	putative substrate translocation pore; other site
1151116009293	heat shock protein HtpX; Provisional; Region: PRK05457
1151116009294	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116009295	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116009296	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116009297	carboxy-terminal protease; Provisional; Region: PRK11186
1151116009298	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1151116009299	protein binding site [polypeptide binding]; other site
1151116009300	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1151116009301	Catalytic dyad [active]
1151116009302	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1151116009303	ProP expression regulator; Provisional; Region: PRK04950
1151116009304	ProQ/FINO family; Region: ProQ; pfam04352
1151116009305	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1151116009306	GAF domain; Region: GAF_2; pfam13185
1151116009307	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1151116009308	Paraquat-inducible protein A; Region: PqiA; pfam04403
1151116009309	Paraquat-inducible protein A; Region: PqiA; pfam04403
1151116009310	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1151116009311	mce related protein; Region: MCE; pfam02470
1151116009312	mce related protein; Region: MCE; pfam02470
1151116009313	mce related protein; Region: MCE; pfam02470
1151116009314	mce related protein; Region: MCE; pfam02470
1151116009315	mce related protein; Region: MCE; pfam02470
1151116009316	mce related protein; Region: MCE; pfam02470
1151116009317	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1151116009318	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116009319	S-adenosylmethionine binding site [chemical binding]; other site
1151116009320	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1151116009321	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116009322	PAS domain; Region: PAS_9; pfam13426
1151116009323	putative active site [active]
1151116009324	heme pocket [chemical binding]; other site
1151116009325	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116009326	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1151116009327	putative active site [active]
1151116009328	heme pocket [chemical binding]; other site
1151116009329	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116009330	putative active site [active]
1151116009331	heme pocket [chemical binding]; other site
1151116009332	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116009333	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116009334	metal binding site [ion binding]; metal-binding site
1151116009335	active site
1151116009336	I-site; other site
1151116009337	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1151116009338	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1151116009339	KWG Leptospira; Region: KWG; pfam07656
1151116009340	KWG Leptospira; Region: KWG; pfam07656
1151116009341	Domain of unknown function (DUF1883); Region: DUF1883; pfam08980
1151116009342	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1151116009343	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
1151116009344	metal binding site [ion binding]; metal-binding site
1151116009345	putative dimer interface [polypeptide binding]; other site
1151116009346	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1151116009347	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1151116009348	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1151116009349	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1151116009350	HAMP domain; Region: HAMP; pfam00672
1151116009351	dimerization interface [polypeptide binding]; other site
1151116009352	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116009353	dimer interface [polypeptide binding]; other site
1151116009354	putative CheW interface [polypeptide binding]; other site
1151116009355	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1151116009356	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1151116009357	Transposase; Region: HTH_Tnp_1; pfam01527
1151116009358	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1151116009359	HTH-like domain; Region: HTH_21; pfam13276
1151116009360	Integrase core domain; Region: rve; pfam00665
1151116009361	Integrase core domain; Region: rve_3; pfam13683
1151116009362	Divergent AAA domain; Region: AAA_4; pfam04326
1151116009363	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1151116009364	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1151116009365	HTH-like domain; Region: HTH_21; pfam13276
1151116009366	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1151116009367	Integrase core domain; Region: rve; pfam00665
1151116009368	Integrase core domain; Region: rve_3; pfam13683
1151116009369	Transposase; Region: HTH_Tnp_1; pfam01527
1151116009370	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1151116009371	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116009372	Coenzyme A binding pocket [chemical binding]; other site
1151116009373	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1151116009374	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1151116009375	Protein of unknown function (DUF3316); Region: DUF3316; pfam11777
1151116009376	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1151116009377	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1151116009378	CopC domain; Region: CopC; cl01012
1151116009379	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1151116009380	Ferritin-like domain; Region: Ferritin; pfam00210
1151116009381	ferroxidase diiron center [ion binding]; other site
1151116009382	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1151116009383	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
1151116009384	protease 2; Provisional; Region: PRK10115
1151116009385	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1151116009386	YebF-like protein; Region: YebF; cl10126
1151116009387	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1151116009388	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1151116009389	ATP binding site [chemical binding]; other site
1151116009390	putative Mg++ binding site [ion binding]; other site
1151116009391	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116009392	nucleotide binding region [chemical binding]; other site
1151116009393	ATP-binding site [chemical binding]; other site
1151116009394	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1151116009395	putative RNA binding site [nucleotide binding]; other site
1151116009396	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1151116009397	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116009398	ATP-grasp domain; Region: ATP-grasp; pfam02222
1151116009399	hypothetical protein; Provisional; Region: PRK05114
1151116009400	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1151116009401	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1151116009402	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1151116009403	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1151116009404	putative active site [active]
1151116009405	putative CoA binding site [chemical binding]; other site
1151116009406	nudix motif; other site
1151116009407	metal binding site [ion binding]; metal-binding site
1151116009408	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1151116009409	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1151116009410	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1151116009411	phage resistance protein; Provisional; Region: PRK10551
1151116009412	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1151116009413	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116009414	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1151116009415	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1151116009416	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1151116009417	Transporter associated domain; Region: CorC_HlyC; smart01091
1151116009418	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1151116009419	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1151116009420	active pocket/dimerization site; other site
1151116009421	active site
1151116009422	phosphorylation site [posttranslational modification]
1151116009423	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1151116009424	active site
1151116009425	phosphorylation site [posttranslational modification]
1151116009426	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1151116009427	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1151116009428	hypothetical protein; Provisional; Region: PRK02913
1151116009429	hypothetical protein; Provisional; Region: PRK11469
1151116009430	Domain of unknown function DUF; Region: DUF204; pfam02659
1151116009431	Domain of unknown function DUF; Region: DUF204; pfam02659
1151116009432	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1151116009433	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116009434	S-adenosylmethionine binding site [chemical binding]; other site
1151116009435	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1151116009436	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1151116009437	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1151116009438	DNA-binding site [nucleotide binding]; DNA binding site
1151116009439	RNA-binding motif; other site
1151116009440	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1151116009441	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1151116009442	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
1151116009443	Protein of unknown function (DUF2591); Region: DUF2591; cl11584
1151116009444	YebO-like protein; Region: YebO; pfam13974
1151116009445	MgrB protein; Region: MgrB; pfam13998
1151116009446	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1151116009447	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1151116009448	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1151116009449	YobH-like protein; Region: YobH; pfam13996
1151116009450	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
1151116009451	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1151116009452	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1151116009453	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1151116009454	peptide binding site [polypeptide binding]; other site
1151116009455	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
1151116009456	isocitrate dehydrogenase; Validated; Region: PRK06451
1151116009457	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1151116009458	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1151116009459	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1151116009460	probable active site [active]
1151116009461	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1151116009462	nudix motif; other site
1151116009463	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1151116009464	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1151116009465	putative lysogenization regulator; Reviewed; Region: PRK00218
1151116009466	adenylosuccinate lyase; Provisional; Region: PRK09285
1151116009467	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1151116009468	tetramer interface [polypeptide binding]; other site
1151116009469	active site
1151116009470	potential frameshift: common BLAST hit: gi|322833620|ref|YP_004213647.1| transposase IS4 family protein
1151116009471	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116009472	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116009473	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116009474	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1151116009475	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116009476	active site
1151116009477	phosphorylation site [posttranslational modification]
1151116009478	intermolecular recognition site; other site
1151116009479	dimerization interface [polypeptide binding]; other site
1151116009480	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116009481	DNA binding site [nucleotide binding]
1151116009482	sensor protein PhoQ; Provisional; Region: PRK10815
1151116009483	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1151116009484	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1151116009485	dimer interface [polypeptide binding]; other site
1151116009486	phosphorylation site [posttranslational modification]
1151116009487	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116009488	ATP binding site [chemical binding]; other site
1151116009489	Mg2+ binding site [ion binding]; other site
1151116009490	G-X-G motif; other site
1151116009491	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1151116009492	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116009493	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116009494	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116009495	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1151116009496	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1151116009497	metal binding site [ion binding]; metal-binding site
1151116009498	dimer interface [polypeptide binding]; other site
1151116009499	NAD-dependent deacetylase; Provisional; Region: PRK00481
1151116009500	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1151116009501	NAD+ binding site [chemical binding]; other site
1151116009502	substrate binding site [chemical binding]; other site
1151116009503	Zn binding site [ion binding]; other site
1151116009504	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1151116009505	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1151116009506	FtsX-like permease family; Region: FtsX; pfam02687
1151116009507	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1151116009508	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1151116009509	Walker A/P-loop; other site
1151116009510	ATP binding site [chemical binding]; other site
1151116009511	Q-loop/lid; other site
1151116009512	ABC transporter signature motif; other site
1151116009513	Walker B; other site
1151116009514	D-loop; other site
1151116009515	H-loop/switch region; other site
1151116009516	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1151116009517	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1151116009518	FtsX-like permease family; Region: FtsX; pfam02687
1151116009519	transcription-repair coupling factor; Provisional; Region: PRK10689
1151116009520	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1151116009521	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116009522	ATP binding site [chemical binding]; other site
1151116009523	putative Mg++ binding site [ion binding]; other site
1151116009524	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116009525	nucleotide binding region [chemical binding]; other site
1151116009526	ATP-binding site [chemical binding]; other site
1151116009527	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1151116009528	hypothetical protein; Provisional; Region: PRK11280
1151116009529	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1151116009530	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1151116009531	hypothetical protein; Provisional; Region: PRK04940
1151116009532	beta-hexosaminidase; Provisional; Region: PRK05337
1151116009533	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1151116009534	thiamine kinase; Region: ycfN_thiK; TIGR02721
1151116009535	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1151116009536	active site
1151116009537	substrate binding site [chemical binding]; other site
1151116009538	ATP binding site [chemical binding]; other site
1151116009539	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1151116009540	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1151116009541	putative dimer interface [polypeptide binding]; other site
1151116009542	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1151116009543	nucleotide binding site/active site [active]
1151116009544	HIT family signature motif; other site
1151116009545	catalytic residue [active]
1151116009546	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116009547	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116009548	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116009549	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1151116009550	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116009551	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116009552	active site turn [active]
1151116009553	phosphorylation site [posttranslational modification]
1151116009554	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1151116009555	active site
1151116009556	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1151116009557	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1151116009558	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1151116009559	thymidylate kinase; Validated; Region: tmk; PRK00698
1151116009560	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1151116009561	TMP-binding site; other site
1151116009562	ATP-binding site [chemical binding]; other site
1151116009563	YceG-like family; Region: YceG; pfam02618
1151116009564	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1151116009565	dimerization interface [polypeptide binding]; other site
1151116009566	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1151116009567	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1151116009568	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116009569	catalytic residue [active]
1151116009570	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1151116009571	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1151116009572	dimer interface [polypeptide binding]; other site
1151116009573	active site
1151116009574	acyl carrier protein; Provisional; Region: acpP; PRK00982
1151116009575	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1151116009576	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1151116009577	NAD(P) binding site [chemical binding]; other site
1151116009578	homotetramer interface [polypeptide binding]; other site
1151116009579	homodimer interface [polypeptide binding]; other site
1151116009580	active site
1151116009581	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1151116009582	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1151116009583	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1151116009584	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1151116009585	dimer interface [polypeptide binding]; other site
1151116009586	active site
1151116009587	CoA binding pocket [chemical binding]; other site
1151116009588	putative phosphate acyltransferase; Provisional; Region: PRK05331
1151116009589	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1151116009590	hypothetical protein; Provisional; Region: PRK11193
1151116009591	Maf-like protein; Region: Maf; pfam02545
1151116009592	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1151116009593	active site
1151116009594	dimer interface [polypeptide binding]; other site
1151116009595	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1151116009596	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1151116009597	RNA binding surface [nucleotide binding]; other site
1151116009598	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1151116009599	active site
1151116009600	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
1151116009601	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1151116009602	homodimer interface [polypeptide binding]; other site
1151116009603	oligonucleotide binding site [chemical binding]; other site
1151116009604	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1151116009605	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1151116009606	active site
1151116009607	substrate binding pocket [chemical binding]; other site
1151116009608	dimer interface [polypeptide binding]; other site
1151116009609	DNA damage-inducible protein I; Provisional; Region: PRK10597
1151116009610	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1151116009611	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1151116009612	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1151116009613	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116009614	DNA binding residues [nucleotide binding]
1151116009615	dimerization interface [polypeptide binding]; other site
1151116009616	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1151116009617	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1151116009618	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1151116009619	Protein export membrane protein; Region: SecD_SecF; cl14618
1151116009620	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1151116009621	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116009622	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116009623	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1151116009624	hypothetical protein; Provisional; Region: PRK03757
1151116009625	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1151116009626	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1151116009627	active site residue [active]
1151116009628	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1151116009629	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1151116009630	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1151116009631	phosphate binding site [ion binding]; other site
1151116009632	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1151116009633	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1151116009634	putative acyl-acceptor binding pocket; other site
1151116009635	DoxX; Region: DoxX; pfam07681
1151116009636	drug efflux system protein MdtG; Provisional; Region: PRK09874
1151116009637	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116009638	putative substrate translocation pore; other site
1151116009639	Animal heme peroxidases and related proteins; Region: An_peroxidase_like; cl14561
1151116009640	MsyB protein; Region: MsyB; cl08181
1151116009641	lipoprotein; Provisional; Region: PRK10175
1151116009642	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1151116009643	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1151116009644	Ligand binding site; other site
1151116009645	DXD motif; other site
1151116009646	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1151116009647	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; cl15433
1151116009648	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1151116009649	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1151116009650	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1151116009651	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116009652	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116009653	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1151116009654	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116009655	putative substrate translocation pore; other site
1151116009656	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1151116009657	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116009658	putative DNA binding site [nucleotide binding]; other site
1151116009659	putative Zn2+ binding site [ion binding]; other site
1151116009660	Bacterial transcriptional regulator; Region: IclR; pfam01614
1151116009661	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1151116009662	Ligand Binding Site [chemical binding]; other site
1151116009663	YccJ-like protein; Region: YccJ; cl08091
1151116009664	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1151116009665	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1151116009666	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1151116009667	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1151116009668	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1151116009669	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1151116009670	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1151116009671	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1151116009672	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1151116009673	active site
1151116009674	catalytic site [active]
1151116009675	putative DNA binding site [nucleotide binding]; other site
1151116009676	GIY-YIG motif/motif A; other site
1151116009677	metal binding site [ion binding]; metal-binding site
1151116009678	UvrB/uvrC motif; Region: UVR; pfam02151
1151116009679	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1151116009680	response regulator; Provisional; Region: PRK09483
1151116009681	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116009682	active site
1151116009683	phosphorylation site [posttranslational modification]
1151116009684	intermolecular recognition site; other site
1151116009685	dimerization interface [polypeptide binding]; other site
1151116009686	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116009687	DNA binding residues [nucleotide binding]
1151116009688	dimerization interface [polypeptide binding]; other site
1151116009689	hypothetical protein; Provisional; Region: PRK10613
1151116009690	Cupin domain; Region: Cupin_2; cl17218
1151116009691	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116009692	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116009693	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116009694	2-isopropylmalate synthase; Validated; Region: PRK03739
1151116009695	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
1151116009696	active site
1151116009697	catalytic residues [active]
1151116009698	metal binding site [ion binding]; metal-binding site
1151116009699	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1151116009700	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1151116009701	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1151116009702	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1151116009703	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
1151116009704	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
1151116009705	Putative glucoamylase; Region: Glycoamylase; pfam10091
1151116009706	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
1151116009707	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1151116009708	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116009709	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1151116009710	pyrimidine utilization protein A; Region: RutA; TIGR03612
1151116009711	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1151116009712	active site
1151116009713	dimer interface [polypeptide binding]; other site
1151116009714	non-prolyl cis peptide bond; other site
1151116009715	insertion regions; other site
1151116009716	Isochorismatase family; Region: Isochorismatase; pfam00857
1151116009717	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1151116009718	catalytic triad [active]
1151116009719	conserved cis-peptide bond; other site
1151116009720	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1151116009721	homotrimer interaction site [polypeptide binding]; other site
1151116009722	putative active site [active]
1151116009723	pyrimidine utilization protein D; Region: RutD; TIGR03611
1151116009724	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
1151116009725	putative FMN binding site [chemical binding]; other site
1151116009726	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
1151116009727	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
1151116009728	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116009729	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_15; cd08492
1151116009730	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116009731	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116009732	dimer interface [polypeptide binding]; other site
1151116009733	conserved gate region; other site
1151116009734	putative PBP binding loops; other site
1151116009735	ABC-ATPase subunit interface; other site
1151116009736	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116009737	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116009738	putative PBP binding loops; other site
1151116009739	ABC-ATPase subunit interface; other site
1151116009740	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1151116009741	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116009742	Walker A/P-loop; other site
1151116009743	ATP binding site [chemical binding]; other site
1151116009744	Q-loop/lid; other site
1151116009745	ABC transporter signature motif; other site
1151116009746	Walker B; other site
1151116009747	D-loop; other site
1151116009748	H-loop/switch region; other site
1151116009749	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116009750	Walker A/P-loop; other site
1151116009751	ATP binding site [chemical binding]; other site
1151116009752	Q-loop/lid; other site
1151116009753	ABC transporter signature motif; other site
1151116009754	Walker B; other site
1151116009755	D-loop; other site
1151116009756	H-loop/switch region; other site
1151116009757	putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family; Region: LLM_KPN_01858; TIGR04027
1151116009758	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1151116009759	CMD domain protein, Avi_7170 family; Region: CMD_Avi_7170; TIGR04029
1151116009760	alkylhydroperoxidase domain protein, Avi_7169 family; Region: perox_Avi_7169; TIGR04030
1151116009761	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
1151116009762	Glyoxalase-like domain; Region: Glyoxalase_3; pfam13468
1151116009763	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1151116009764	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116009765	Walker A/P-loop; other site
1151116009766	ATP binding site [chemical binding]; other site
1151116009767	Q-loop/lid; other site
1151116009768	ABC transporter signature motif; other site
1151116009769	Walker B; other site
1151116009770	D-loop; other site
1151116009771	H-loop/switch region; other site
1151116009772	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116009773	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116009774	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116009775	TM-ABC transporter signature motif; other site
1151116009776	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1151116009777	Sec-independent protein translocase protein (TatC); Region: TatC; cl00521
1151116009778	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116009779	Coenzyme A binding pocket [chemical binding]; other site
1151116009780	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1151116009781	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116009782	sequence-specific DNA binding site [nucleotide binding]; other site
1151116009783	salt bridge; other site
1151116009784	Cupin domain; Region: Cupin_2; cl17218
1151116009785	transcriptional regulator MirA; Provisional; Region: PRK15043
1151116009786	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1151116009787	DNA binding residues [nucleotide binding]
1151116009788	SnoaL-like domain; Region: SnoaL_2; pfam12680
1151116009789	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116009790	NAD(P) binding site [chemical binding]; other site
1151116009791	active site
1151116009792	Predicted NAD/FAD-binding protein [General function prediction only]; Region: COG2907
1151116009793	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1151116009794	Protein of unknown function (DUF1365); Region: DUF1365; pfam07103
1151116009795	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
1151116009796	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116009797	S-adenosylmethionine binding site [chemical binding]; other site
1151116009798	Protein of unknown function (DUF2878); Region: DUF2878; pfam11086
1151116009799	Protein of unknown function (DUF3833); Region: DUF3833; pfam12915
1151116009800	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1151116009801	EamA-like transporter family; Region: EamA; pfam00892
1151116009802	EamA-like transporter family; Region: EamA; pfam00892
1151116009803	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116009804	putative PBP binding loops; other site
1151116009805	dimer interface [polypeptide binding]; other site
1151116009806	ABC-ATPase subunit interface; other site
1151116009807	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1151116009808	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1151116009809	Walker A/P-loop; other site
1151116009810	ATP binding site [chemical binding]; other site
1151116009811	Q-loop/lid; other site
1151116009812	ABC transporter signature motif; other site
1151116009813	Walker B; other site
1151116009814	D-loop; other site
1151116009815	H-loop/switch region; other site
1151116009816	CBS domain; Region: CBS; pfam00571
1151116009817	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116009818	dimer interface [polypeptide binding]; other site
1151116009819	conserved gate region; other site
1151116009820	ABC-ATPase subunit interface; other site
1151116009821	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1151116009822	benzoate transport; Region: 2A0115; TIGR00895
1151116009823	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116009824	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116009825	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
1151116009826	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
1151116009827	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116009828	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116009829	dimerization interface [polypeptide binding]; other site
1151116009830	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
1151116009831	amidohydrolase; Region: amidohydrolases; TIGR01891
1151116009832	putative metal binding site [ion binding]; other site
1151116009833	dimer interface [polypeptide binding]; other site
1151116009834	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
1151116009835	amidohydrolase; Region: amidohydrolases; TIGR01891
1151116009836	putative metal binding site [ion binding]; other site
1151116009837	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
1151116009838	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1151116009839	Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; cl01472
1151116009840	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116009841	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116009842	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116009843	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116009844	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116009845	H+ Antiporter protein; Region: 2A0121; TIGR00900
1151116009846	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1151116009847	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
1151116009848	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1151116009849	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1151116009850	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1151116009851	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1151116009852	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1151116009853	NAD(P) binding site [chemical binding]; other site
1151116009854	catalytic residues [active]
1151116009855	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1151116009856	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1151116009857	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116009858	dimer interface [polypeptide binding]; other site
1151116009859	conserved gate region; other site
1151116009860	putative PBP binding loops; other site
1151116009861	ABC-ATPase subunit interface; other site
1151116009862	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1151116009863	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116009864	dimer interface [polypeptide binding]; other site
1151116009865	conserved gate region; other site
1151116009866	putative PBP binding loops; other site
1151116009867	ABC-ATPase subunit interface; other site
1151116009868	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
1151116009869	Transferrin; Region: Transferrin; cl02460
1151116009870	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
1151116009871	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1151116009872	Walker A/P-loop; other site
1151116009873	ATP binding site [chemical binding]; other site
1151116009874	Q-loop/lid; other site
1151116009875	ABC transporter signature motif; other site
1151116009876	Walker B; other site
1151116009877	D-loop; other site
1151116009878	H-loop/switch region; other site
1151116009879	D-lactate dehydrogenase; Provisional; Region: PRK11183
1151116009880	FAD binding domain; Region: FAD_binding_4; pfam01565
1151116009881	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1151116009882	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1151116009883	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1151116009884	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1151116009885	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1151116009886	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1151116009887	FMN binding site [chemical binding]; other site
1151116009888	active site
1151116009889	catalytic residues [active]
1151116009890	substrate binding site [chemical binding]; other site
1151116009891	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116009892	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116009893	putative substrate translocation pore; other site
1151116009894	Predicted transcriptional regulator [Transcription]; Region: COG2345
1151116009895	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1151116009896	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1151116009897	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1151116009898	ATP binding site [chemical binding]; other site
1151116009899	Mg++ binding site [ion binding]; other site
1151116009900	motif III; other site
1151116009901	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116009902	nucleotide binding region [chemical binding]; other site
1151116009903	ATP-binding site [chemical binding]; other site
1151116009904	drug efflux system protein MdtG; Provisional; Region: PRK09874
1151116009905	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116009906	putative substrate translocation pore; other site
1151116009907	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1151116009908	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1151116009909	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1151116009910	MoaE homodimer interface [polypeptide binding]; other site
1151116009911	MoaD interaction [polypeptide binding]; other site
1151116009912	active site residues [active]
1151116009913	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1151116009914	MoaE interaction surface [polypeptide binding]; other site
1151116009915	MoeB interaction surface [polypeptide binding]; other site
1151116009916	thiocarboxylated glycine; other site
1151116009917	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1151116009918	trimer interface [polypeptide binding]; other site
1151116009919	dimer interface [polypeptide binding]; other site
1151116009920	putative active site [active]
1151116009921	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1151116009922	MPT binding site; other site
1151116009923	trimer interface [polypeptide binding]; other site
1151116009924	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1151116009925	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116009926	FeS/SAM binding site; other site
1151116009927	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1151116009928	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1151116009929	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1151116009930	phosphate binding site [ion binding]; other site
1151116009931	putative substrate binding pocket [chemical binding]; other site
1151116009932	dimer interface [polypeptide binding]; other site
1151116009933	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1151116009934	Isochorismatase family; Region: Isochorismatase; pfam00857
1151116009935	catalytic triad [active]
1151116009936	conserved cis-peptide bond; other site
1151116009937	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
1151116009938	excinuclease ABC subunit B; Provisional; Region: PRK05298
1151116009939	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116009940	ATP binding site [chemical binding]; other site
1151116009941	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116009942	nucleotide binding region [chemical binding]; other site
1151116009943	ATP-binding site [chemical binding]; other site
1151116009944	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1151116009945	UvrB/uvrC motif; Region: UVR; pfam02151
1151116009946	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
1151116009947	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1151116009948	Walker A/P-loop; other site
1151116009949	ATP binding site [chemical binding]; other site
1151116009950	Q-loop/lid; other site
1151116009951	ABC transporter signature motif; other site
1151116009952	Walker B; other site
1151116009953	D-loop; other site
1151116009954	H-loop/switch region; other site
1151116009955	AAA domain; Region: AAA_26; pfam13500
1151116009956	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1151116009957	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
1151116009958	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1151116009959	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116009960	S-adenosylmethionine binding site [chemical binding]; other site
1151116009961	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
1151116009962	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
1151116009963	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116009964	catalytic residue [active]
1151116009965	biotin synthase; Provisional; Region: PRK15108
1151116009966	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116009967	FeS/SAM binding site; other site
1151116009968	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1151116009969	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1151116009970	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1151116009971	inhibitor-cofactor binding pocket; inhibition site
1151116009972	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116009973	catalytic residue [active]
1151116009974	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1151116009975	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116009976	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1151116009977	dimerization interface [polypeptide binding]; other site
1151116009978	substrate binding pocket [chemical binding]; other site
1151116009979	putative aminotransferase; Provisional; Region: PRK12414
1151116009980	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116009981	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116009982	homodimer interface [polypeptide binding]; other site
1151116009983	catalytic residue [active]
1151116009984	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1151116009985	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116009986	substrate binding pocket [chemical binding]; other site
1151116009987	membrane-bound complex binding site; other site
1151116009988	hinge residues; other site
1151116009989	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116009990	active site
1151116009991	motif I; other site
1151116009992	motif II; other site
1151116009993	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1151116009994	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1151116009995	NAD(P) binding site [chemical binding]; other site
1151116009996	substrate binding site [chemical binding]; other site
1151116009997	dimer interface [polypeptide binding]; other site
1151116009998	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
1151116009999	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1151116010000	potential catalytic triad [active]
1151116010001	conserved cys residue [active]
1151116010002	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1151116010003	substrate binding site [chemical binding]; other site
1151116010004	acyl-CoA thioesterase; Provisional; Region: PRK10531
1151116010005	putative pectinesterase; Region: PLN02432; cl01911
1151116010006	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116010007	dimerization interface [polypeptide binding]; other site
1151116010008	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1151116010009	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116010010	dimer interface [polypeptide binding]; other site
1151116010011	putative CheW interface [polypeptide binding]; other site
1151116010012	6-phosphogluconolactonase; Provisional; Region: PRK11028
1151116010013	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1151116010014	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116010015	active site
1151116010016	motif I; other site
1151116010017	motif II; other site
1151116010018	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116010019	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
1151116010020	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1151116010021	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116010022	non-specific DNA binding site [nucleotide binding]; other site
1151116010023	salt bridge; other site
1151116010024	sequence-specific DNA binding site [nucleotide binding]; other site
1151116010025	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1151116010026	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116010027	Walker A/P-loop; other site
1151116010028	ATP binding site [chemical binding]; other site
1151116010029	Q-loop/lid; other site
1151116010030	ABC transporter signature motif; other site
1151116010031	Walker B; other site
1151116010032	D-loop; other site
1151116010033	H-loop/switch region; other site
1151116010034	TOBE domain; Region: TOBE; pfam03459
1151116010035	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1151116010036	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116010037	dimer interface [polypeptide binding]; other site
1151116010038	conserved gate region; other site
1151116010039	putative PBP binding loops; other site
1151116010040	ABC-ATPase subunit interface; other site
1151116010041	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1151116010042	molybdenum ABC transporter, periplasmic molybdate-binding protein; Region: modA; TIGR01256
1151116010043	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1151116010044	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1151116010045	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1151116010046	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1151116010047	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
1151116010048	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1151116010049	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116010050	Walker A/P-loop; other site
1151116010051	ATP binding site [chemical binding]; other site
1151116010052	Q-loop/lid; other site
1151116010053	ABC transporter signature motif; other site
1151116010054	Walker B; other site
1151116010055	D-loop; other site
1151116010056	H-loop/switch region; other site
1151116010057	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116010058	Walker A/P-loop; other site
1151116010059	ATP binding site [chemical binding]; other site
1151116010060	Q-loop/lid; other site
1151116010061	ABC transporter signature motif; other site
1151116010062	Walker B; other site
1151116010063	D-loop; other site
1151116010064	H-loop/switch region; other site
1151116010065	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1151116010066	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1151116010067	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116010068	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116010069	dimerization interface [polypeptide binding]; other site
1151116010070	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1151116010071	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1151116010072	NAD binding site [chemical binding]; other site
1151116010073	homodimer interface [polypeptide binding]; other site
1151116010074	active site
1151116010075	substrate binding site [chemical binding]; other site
1151116010076	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1151116010077	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1151116010078	dimer interface [polypeptide binding]; other site
1151116010079	active site
1151116010080	galactokinase; Provisional; Region: PRK05101
1151116010081	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1151116010082	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1151116010083	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1151116010084	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1151116010085	active site
1151116010086	catalytic residues [active]
1151116010087	psiF repeat; Region: PsiF_repeat; pfam07769
1151116010088	psiF repeat; Region: PsiF_repeat; pfam07769
1151116010089	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1151116010090	catalytic core [active]
1151116010091	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1151116010092	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1151116010093	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1151116010094	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116010095	Coenzyme A binding pocket [chemical binding]; other site
1151116010096	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1151116010097	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1151116010098	YbgS-like protein; Region: YbgS; pfam13985
1151116010099	Cation efflux family; Region: Cation_efflux; cl00316
1151116010100	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1151116010101	quinolinate synthetase; Provisional; Region: PRK09375
1151116010102	tol-pal system protein YbgF; Provisional; Region: PRK10803
1151116010103	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1151116010104	binding surface
1151116010105	TPR motif; other site
1151116010106	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1151116010107	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1151116010108	ligand binding site [chemical binding]; other site
1151116010109	translocation protein TolB; Provisional; Region: tolB; PRK03629
1151116010110	TolB amino-terminal domain; Region: TolB_N; pfam04052
1151116010111	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1151116010112	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1151116010113	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1151116010114	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1151116010115	TolA C-terminal; Region: TolA; pfam06519
1151116010116	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1151116010117	colicin uptake protein TolR; Provisional; Region: PRK11024
1151116010118	colicin uptake protein TolQ; Provisional; Region: PRK10801
1151116010119	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1151116010120	active site
1151116010121	hypothetical protein; Provisional; Region: PRK10588
1151116010122	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1151116010123	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1151116010124	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1151116010125	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1151116010126	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1151116010127	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116010128	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116010129	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116010130	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1151116010131	CoA binding domain; Region: CoA_binding; smart00881
1151116010132	CoA-ligase; Region: Ligase_CoA; pfam00549
1151116010133	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1151116010134	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1151116010135	CoA-ligase; Region: Ligase_CoA; pfam00549
1151116010136	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1151116010137	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1151116010138	E3 interaction surface; other site
1151116010139	lipoyl attachment site [posttranslational modification]; other site
1151116010140	e3 binding domain; Region: E3_binding; pfam02817
1151116010141	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1151116010142	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1151116010143	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1151116010144	TPP-binding site [chemical binding]; other site
1151116010145	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1151116010146	dimer interface [polypeptide binding]; other site
1151116010147	PYR/PP interface [polypeptide binding]; other site
1151116010148	TPP binding site [chemical binding]; other site
1151116010149	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1151116010150	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1151116010151	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1151116010152	L-aspartate oxidase; Provisional; Region: PRK06175
1151116010153	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1151116010154	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1151116010155	SdhC subunit interface [polypeptide binding]; other site
1151116010156	proximal heme binding site [chemical binding]; other site
1151116010157	cardiolipin binding site; other site
1151116010158	Iron-sulfur protein interface; other site
1151116010159	proximal quinone binding site [chemical binding]; other site
1151116010160	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1151116010161	Iron-sulfur protein interface; other site
1151116010162	proximal quinone binding site [chemical binding]; other site
1151116010163	SdhD (CybS) interface [polypeptide binding]; other site
1151116010164	proximal heme binding site [chemical binding]; other site
1151116010165	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1151116010166	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1151116010167	dimer interface [polypeptide binding]; other site
1151116010168	active site
1151116010169	citrylCoA binding site [chemical binding]; other site
1151116010170	NADH binding [chemical binding]; other site
1151116010171	cationic pore residues; other site
1151116010172	oxalacetate/citrate binding site [chemical binding]; other site
1151116010173	coenzyme A binding site [chemical binding]; other site
1151116010174	catalytic triad [active]
1151116010175	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1151116010176	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1151116010177	Autotransporter beta-domain; Region: Autotransporter; smart00869
1151116010178	endonuclease VIII; Provisional; Region: PRK10445
1151116010179	N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei (endonuclease VIII) base-excision repair DNA glycosylases; Region: FpgNei_N; cl03119
1151116010180	DNA binding site [nucleotide binding]
1151116010181	catalytic residue [active]
1151116010182	H2TH interface [polypeptide binding]; other site
1151116010183	putative catalytic residues [active]
1151116010184	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1151116010185	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1151116010186	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
1151116010187	putative substrate binding pocket [chemical binding]; other site
1151116010188	AC domain interface; other site
1151116010189	catalytic triad [active]
1151116010190	AB domain interface; other site
1151116010191	interchain disulfide; other site
1151116010192	LamB/YcsF family protein; Provisional; Region: PRK05406
1151116010193	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1151116010194	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1151116010195	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
1151116010196	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116010197	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116010198	putative substrate translocation pore; other site
1151116010199	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1151116010200	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
1151116010201	cAMP phosphodiesterases class-II; Region: PDEase_II; cl17776
1151116010202	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1151116010203	DNA photolyase; Region: DNA_photolyase; pfam00875
1151116010204	Protein of unknown function (DUF523); Region: DUF523; pfam04463
1151116010205	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1151116010206	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1151116010207	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1151116010208	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1151116010209	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1151116010210	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1151116010211	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1151116010212	sensor protein KdpD; Provisional; Region: PRK10490
1151116010213	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1151116010214	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1151116010215	Ligand Binding Site [chemical binding]; other site
1151116010216	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1151116010217	GAF domain; Region: GAF_3; pfam13492
1151116010218	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116010219	dimer interface [polypeptide binding]; other site
1151116010220	phosphorylation site [posttranslational modification]
1151116010221	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116010222	ATP binding site [chemical binding]; other site
1151116010223	Mg2+ binding site [ion binding]; other site
1151116010224	G-X-G motif; other site
1151116010225	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1151116010226	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116010227	active site
1151116010228	phosphorylation site [posttranslational modification]
1151116010229	intermolecular recognition site; other site
1151116010230	dimerization interface [polypeptide binding]; other site
1151116010231	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116010232	DNA binding site [nucleotide binding]
1151116010233	Predicted transcriptional regulators [Transcription]; Region: COG1695
1151116010234	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1151116010235	phosphoglucomutase; Validated; Region: PRK07564
1151116010236	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1151116010237	active site
1151116010238	substrate binding site [chemical binding]; other site
1151116010239	metal binding site [ion binding]; metal-binding site
1151116010240	replication initiation regulator SeqA; Provisional; Region: PRK11187
1151116010241	acyl-CoA esterase; Provisional; Region: PRK10673
1151116010242	PGAP1-like protein; Region: PGAP1; pfam07819
1151116010243	LexA regulated protein; Provisional; Region: PRK11675
1151116010244	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1151116010245	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
1151116010246	dimer interface [polypeptide binding]; other site
1151116010247	ligand binding site [chemical binding]; other site
1151116010248	HAMP domain; Region: HAMP; pfam00672
1151116010249	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116010250	dimer interface [polypeptide binding]; other site
1151116010251	putative CheW interface [polypeptide binding]; other site
1151116010252	flavodoxin FldA; Validated; Region: PRK09267
1151116010253	ferric uptake regulator; Provisional; Region: fur; PRK09462
1151116010254	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1151116010255	metal binding site 2 [ion binding]; metal-binding site
1151116010256	putative DNA binding helix; other site
1151116010257	metal binding site 1 [ion binding]; metal-binding site
1151116010258	dimer interface [polypeptide binding]; other site
1151116010259	structural Zn2+ binding site [ion binding]; other site
1151116010260	YbfN-like lipoprotein; Region: YbfN; pfam13982
1151116010261	outer membrane porin, OprD family; Region: OprD; pfam03573
1151116010262	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1151116010263	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1151116010264	active site
1151116010265	HIGH motif; other site
1151116010266	nucleotide binding site [chemical binding]; other site
1151116010267	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1151116010268	KMSKS motif; other site
1151116010269	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1151116010270	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1151116010271	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116010272	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116010273	active site turn [active]
1151116010274	phosphorylation site [posttranslational modification]
1151116010275	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1151116010276	HPr interaction site; other site
1151116010277	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1151116010278	active site
1151116010279	phosphorylation site [posttranslational modification]
1151116010280	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1151116010281	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1151116010282	active site
1151116010283	trimer interface [polypeptide binding]; other site
1151116010284	allosteric site; other site
1151116010285	active site lid [active]
1151116010286	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1151116010287	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1151116010288	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1151116010289	active site
1151116010290	dimer interface [polypeptide binding]; other site
1151116010291	MarR family; Region: MarR; pfam01047
1151116010292	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1151116010293	ROK family; Region: ROK; pfam00480
1151116010294	UMP phosphatase; Provisional; Region: PRK10444
1151116010295	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116010296	active site
1151116010297	motif I; other site
1151116010298	motif II; other site
1151116010299	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116010300	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1151116010301	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1151116010302	active site
1151116010303	dimer interface [polypeptide binding]; other site
1151116010304	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1151116010305	Ligand Binding Site [chemical binding]; other site
1151116010306	Molecular Tunnel; other site
1151116010307	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1151116010308	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1151116010309	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1151116010310	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1151116010311	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116010312	FeS/SAM binding site; other site
1151116010313	TRAM domain; Region: TRAM; pfam01938
1151116010314	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1151116010315	PhoH-like protein; Region: PhoH; pfam02562
1151116010316	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1151116010317	metal-binding heat shock protein; Provisional; Region: PRK00016
1151116010318	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1151116010319	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1151116010320	Transporter associated domain; Region: CorC_HlyC; smart01091
1151116010321	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1151116010322	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1151116010323	putative active site [active]
1151116010324	catalytic triad [active]
1151116010325	putative dimer interface [polypeptide binding]; other site
1151116010326	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1151116010327	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116010328	substrate binding pocket [chemical binding]; other site
1151116010329	membrane-bound complex binding site; other site
1151116010330	hinge residues; other site
1151116010331	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116010332	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116010333	dimer interface [polypeptide binding]; other site
1151116010334	conserved gate region; other site
1151116010335	putative PBP binding loops; other site
1151116010336	ABC-ATPase subunit interface; other site
1151116010337	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116010338	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116010339	dimer interface [polypeptide binding]; other site
1151116010340	conserved gate region; other site
1151116010341	putative PBP binding loops; other site
1151116010342	ABC-ATPase subunit interface; other site
1151116010343	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116010344	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116010345	Walker A/P-loop; other site
1151116010346	ATP binding site [chemical binding]; other site
1151116010347	Q-loop/lid; other site
1151116010348	ABC transporter signature motif; other site
1151116010349	Walker B; other site
1151116010350	D-loop; other site
1151116010351	H-loop/switch region; other site
1151116010352	hypothetical protein; Provisional; Region: PRK11032
1151116010353	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1151116010354	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1151116010355	HIGH motif; other site
1151116010356	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1151116010357	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1151116010358	active site
1151116010359	KMSKS motif; other site
1151116010360	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1151116010361	tRNA binding surface [nucleotide binding]; other site
1151116010362	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1151116010363	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1151116010364	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1151116010365	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1151116010366	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1151116010367	active site
1151116010368	(T/H)XGH motif; other site
1151116010369	ribosome-associated protein; Provisional; Region: PRK11538
1151116010370	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1151116010371	penicillin-binding protein 2; Provisional; Region: PRK10795
1151116010372	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1151116010373	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1151116010374	cell wall shape-determining protein; Provisional; Region: PRK10794
1151116010375	rare lipoprotein A; Provisional; Region: PRK10672
1151116010376	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1151116010377	Sporulation related domain; Region: SPOR; pfam05036
1151116010378	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1151116010379	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1151116010380	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1151116010381	hypothetical protein; Provisional; Region: PRK04998
1151116010382	lipoate-protein ligase B; Provisional; Region: PRK14342
1151116010383	lipoyl synthase; Provisional; Region: PRK05481
1151116010384	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116010385	FeS/SAM binding site; other site
1151116010386	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1151116010387	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116010388	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116010389	Walker A/P-loop; other site
1151116010390	ATP binding site [chemical binding]; other site
1151116010391	Q-loop/lid; other site
1151116010392	ABC transporter signature motif; other site
1151116010393	Walker B; other site
1151116010394	D-loop; other site
1151116010395	H-loop/switch region; other site
1151116010396	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116010397	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116010398	dimer interface [polypeptide binding]; other site
1151116010399	conserved gate region; other site
1151116010400	putative PBP binding loops; other site
1151116010401	ABC-ATPase subunit interface; other site
1151116010402	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116010403	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116010404	substrate binding pocket [chemical binding]; other site
1151116010405	membrane-bound complex binding site; other site
1151116010406	hinge residues; other site
1151116010407	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1151116010408	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1151116010409	putative active site [active]
1151116010410	catalytic triad [active]
1151116010411	putative dimer interface [polypeptide binding]; other site
1151116010412	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
1151116010413	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116010414	DNA-binding site [nucleotide binding]; DNA binding site
1151116010415	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116010416	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116010417	homodimer interface [polypeptide binding]; other site
1151116010418	catalytic residue [active]
1151116010419	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1151116010420	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116010421	Coenzyme A binding pocket [chemical binding]; other site
1151116010422	chromosome condensation membrane protein; Provisional; Region: PRK14196
1151116010423	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116010424	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116010425	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1151116010426	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116010427	putative substrate translocation pore; other site
1151116010428	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1151116010429	DNA-binding site [nucleotide binding]; DNA binding site
1151116010430	RNA-binding motif; other site
1151116010431	Uncharacterized protein conserved in bacteria (DUF2076); Region: DUF2076; pfam09849
1151116010432	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
1151116010433	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1151116010434	intersubunit interface [polypeptide binding]; other site
1151116010435	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
1151116010436	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1151116010437	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1151116010438	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1151116010439	anti-adapter protein IraM; Provisional; Region: PRK09919
1151116010440	Cupin domain; Region: Cupin_2; cl17218
1151116010441	MASE2 domain; Region: MASE2; pfam05230
1151116010442	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116010443	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116010444	metal binding site [ion binding]; metal-binding site
1151116010445	active site
1151116010446	I-site; other site
1151116010447	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1151116010448	maltose O-acetyltransferase; Provisional; Region: PRK10092
1151116010449	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1151116010450	active site
1151116010451	substrate binding site [chemical binding]; other site
1151116010452	trimer interface [polypeptide binding]; other site
1151116010453	CoA binding site [chemical binding]; other site
1151116010454	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1151116010455	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116010456	putative substrate translocation pore; other site
1151116010457	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116010458	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
1151116010459	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
1151116010460	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
1151116010461	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1151116010462	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1151116010463	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1151116010464	Surface antigen; Region: Bac_surface_Ag; pfam01103
1151116010465	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1151116010466	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1151116010467	active site
1151116010468	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1151116010469	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1151116010470	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
1151116010471	NAD binding site [chemical binding]; other site
1151116010472	dimer interface [polypeptide binding]; other site
1151116010473	substrate binding site [chemical binding]; other site
1151116010474	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1151116010475	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1151116010476	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1151116010477	homodimer interface [polypeptide binding]; other site
1151116010478	NADP binding site [chemical binding]; other site
1151116010479	substrate binding site [chemical binding]; other site
1151116010480	S4 domain; Region: S4_2; cl17325
1151116010481	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1151116010482	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1151116010483	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1151116010484	dimer interface [polypeptide binding]; other site
1151116010485	ADP-ribose binding site [chemical binding]; other site
1151116010486	active site
1151116010487	nudix motif; other site
1151116010488	metal binding site [ion binding]; metal-binding site
1151116010489	Uncharacterized protein conserved in bacteria (DUF2131); Region: DUF2131; cl11547
1151116010490	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1151116010491	Protein export membrane protein; Region: SecD_SecF; cl14618
1151116010492	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1151116010493	ArsC family; Region: ArsC; pfam03960
1151116010494	putative catalytic residues [active]
1151116010495	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1151116010496	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1151116010497	metal binding site [ion binding]; metal-binding site
1151116010498	dimer interface [polypeptide binding]; other site
1151116010499	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
1151116010500	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1151116010501	Uncharacterized protein family (UPF0370); Region: UPF0370; pfam13980
1151116010502	alpha-L-glutamate ligases, RimK family; Region: rimK_fam; TIGR00768
1151116010503	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1151116010504	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1151116010505	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116010506	catalytic residue [active]
1151116010507	putative hydrolase; Provisional; Region: PRK11460
1151116010508	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
1151116010509	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1151116010510	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
1151116010511	Helicase; Region: Helicase_RecD; pfam05127
1151116010512	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116010513	Coenzyme A binding pocket [chemical binding]; other site
1151116010514	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1151116010515	Predicted membrane protein [Function unknown]; Region: COG2707
1151116010516	Predicted metalloprotease [General function prediction only]; Region: COG2321
1151116010517	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1151116010518	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1151116010519	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1151116010520	ATP binding site [chemical binding]; other site
1151116010521	active site
1151116010522	substrate binding site [chemical binding]; other site
1151116010523	lipoprotein; Provisional; Region: PRK11679
1151116010524	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1151116010525	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1151116010526	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1151116010527	dimer interface [polypeptide binding]; other site
1151116010528	active site
1151116010529	catalytic residue [active]
1151116010530	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1151116010531	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1151116010532	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1151116010533	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1151116010534	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1151116010535	catalytic triad [active]
1151116010536	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1151116010537	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1151116010538	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1151116010539	Peptidase family M48; Region: Peptidase_M48; pfam01435
1151116010540	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1151116010541	ArsC family; Region: ArsC; pfam03960
1151116010542	catalytic residues [active]
1151116010543	DNA replication initiation factor; Provisional; Region: PRK08084
1151116010544	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1151116010545	uracil transporter; Provisional; Region: PRK10720
1151116010546	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1151116010547	active site
1151116010548	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1151116010549	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1151116010550	dimerization interface [polypeptide binding]; other site
1151116010551	putative ATP binding site [chemical binding]; other site
1151116010552	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1151116010553	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1151116010554	active site
1151116010555	substrate binding site [chemical binding]; other site
1151116010556	cosubstrate binding site; other site
1151116010557	catalytic site [active]
1151116010558	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1151116010559	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116010560	Coenzyme A binding pocket [chemical binding]; other site
1151116010561	polyphosphate kinase; Provisional; Region: PRK05443
1151116010562	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1151116010563	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1151116010564	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
1151116010565	domain interface [polypeptide binding]; other site
1151116010566	active site
1151116010567	catalytic site [active]
1151116010568	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1151116010569	domain interface [polypeptide binding]; other site
1151116010570	active site
1151116010571	catalytic site [active]
1151116010572	exopolyphosphatase; Provisional; Region: PRK10854
1151116010573	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116010574	nucleotide binding site [chemical binding]; other site
1151116010575	MASE1; Region: MASE1; cl17823
1151116010576	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116010577	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1151116010578	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116010579	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1151116010580	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1151116010581	MgtE intracellular N domain; Region: MgtE_N; smart00924
1151116010582	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1151116010583	Divalent cation transporter; Region: MgtE; cl00786
1151116010584	MASE1; Region: MASE1; cl17823
1151116010585	PAS domain S-box; Region: sensory_box; TIGR00229
1151116010586	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116010587	putative active site [active]
1151116010588	heme pocket [chemical binding]; other site
1151116010589	PAS fold; Region: PAS; pfam00989
1151116010590	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116010591	putative active site [active]
1151116010592	heme pocket [chemical binding]; other site
1151116010593	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116010594	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116010595	metal binding site [ion binding]; metal-binding site
1151116010596	active site
1151116010597	I-site; other site
1151116010598	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1151116010599	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1151116010600	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1151116010601	minor groove reading motif; other site
1151116010602	helix-hairpin-helix signature motif; other site
1151116010603	substrate binding pocket [chemical binding]; other site
1151116010604	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1151116010605	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1151116010606	active site
1151116010607	HIGH motif; other site
1151116010608	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1151116010609	KMSKS motif; other site
1151116010610	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1151116010611	tRNA binding surface [nucleotide binding]; other site
1151116010612	anticodon binding site; other site
1151116010613	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1151116010614	substrate binding site [chemical binding]; other site
1151116010615	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1151116010616	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1151116010617	putative active site [active]
1151116010618	putative metal binding site [ion binding]; other site
1151116010619	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1151116010620	active site
1151116010621	dinuclear metal binding site [ion binding]; other site
1151116010622	dimerization interface [polypeptide binding]; other site
1151116010623	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1151116010624	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1151116010625	ATP-grasp domain; Region: ATP-grasp; pfam02222
1151116010626	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1151116010627	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1151116010628	FtsX-like permease family; Region: FtsX; pfam02687
1151116010629	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1151116010630	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1151116010631	Walker A/P-loop; other site
1151116010632	ATP binding site [chemical binding]; other site
1151116010633	Q-loop/lid; other site
1151116010634	ABC transporter signature motif; other site
1151116010635	Walker B; other site
1151116010636	D-loop; other site
1151116010637	H-loop/switch region; other site
1151116010638	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1151116010639	active site
1151116010640	catalytic triad [active]
1151116010641	oxyanion hole [active]
1151116010642	switch loop; other site
1151116010643	oxidoreductase; Provisional; Region: PRK08017
1151116010644	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1151116010645	NADP binding site [chemical binding]; other site
1151116010646	active site
1151116010647	steroid binding site; other site
1151116010648	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1151116010649	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1151116010650	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1151116010651	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1151116010652	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1151116010653	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1151116010654	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1151116010655	DNA binding residues [nucleotide binding]
1151116010656	dimer interface [polypeptide binding]; other site
1151116010657	copper binding site [ion binding]; other site
1151116010658	copper exporting ATPase; Provisional; Region: copA; PRK10671
1151116010659	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1151116010660	metal-binding site [ion binding]
1151116010661	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1151116010662	metal-binding site [ion binding]
1151116010663	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1151116010664	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116010665	motif II; other site
1151116010666	TraB family; Region: TraB; cl12050
1151116010667	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1151116010668	putative deacylase active site [active]
1151116010669	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116010670	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116010671	putative substrate translocation pore; other site
1151116010672	putative cation:proton antiport protein; Provisional; Region: PRK10669
1151116010673	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1151116010674	TrkA-N domain; Region: TrkA_N; pfam02254
1151116010675	inosine/guanosine kinase; Provisional; Region: PRK15074
1151116010676	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116010677	substrate binding site [chemical binding]; other site
1151116010678	ATP binding site [chemical binding]; other site
1151116010679	ferrochelatase; Reviewed; Region: hemH; PRK00035
1151116010680	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1151116010681	C-terminal domain interface [polypeptide binding]; other site
1151116010682	active site
1151116010683	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1151116010684	active site
1151116010685	N-terminal domain interface [polypeptide binding]; other site
1151116010686	adenylate kinase; Reviewed; Region: adk; PRK00279
1151116010687	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1151116010688	AMP-binding site [chemical binding]; other site
1151116010689	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1151116010690	heat shock protein 90; Provisional; Region: PRK05218
1151116010691	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116010692	ATP binding site [chemical binding]; other site
1151116010693	Mg2+ binding site [ion binding]; other site
1151116010694	G-X-G motif; other site
1151116010695	recombination protein RecR; Reviewed; Region: recR; PRK00076
1151116010696	RecR protein; Region: RecR; pfam02132
1151116010697	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1151116010698	putative active site [active]
1151116010699	putative metal-binding site [ion binding]; other site
1151116010700	tetramer interface [polypeptide binding]; other site
1151116010701	hypothetical protein; Validated; Region: PRK00153
1151116010702	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14961
1151116010703	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116010704	Walker A motif; other site
1151116010705	ATP binding site [chemical binding]; other site
1151116010706	Walker B motif; other site
1151116010707	arginine finger; other site
1151116010708	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1151116010709	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1151116010710	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1151116010711	alpha-amylase; Reviewed; Region: malS; PRK09505
1151116010712	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1151116010713	active site
1151116010714	catalytic site [active]
1151116010715	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1151116010716	active site
1151116010717	hypothetical protein; Provisional; Region: PRK10527
1151116010718	Primosomal replication protein priB and priC; Region: priB_priC; pfam07445
1151116010719	hypothetical protein; Provisional; Region: PRK11038
1151116010720	hypothetical protein; Provisional; Region: PRK11281
1151116010721	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1151116010722	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1151116010723	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1151116010724	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116010725	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1151116010726	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1151116010727	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116010728	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116010729	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1151116010730	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1151116010731	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1151116010732	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1151116010733	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1151116010734	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1151116010735	metal binding site [ion binding]; metal-binding site
1151116010736	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1151116010737	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116010738	ABC-ATPase subunit  interface; other site
1151116010739	dimer interface [polypeptide binding]; other site
1151116010740	putative PBP binding regions; other site
1151116010741	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1151116010742	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1151116010743	Hha toxicity attenuator; Provisional; Region: PRK10667
1151116010744	gene expression modulator; Provisional; Region: PRK10945
1151116010745	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116010746	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116010747	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116010748	dimerization interface [polypeptide binding]; other site
1151116010749	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1151116010750	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1151116010751	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1151116010752	active site
1151116010753	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1151116010754	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1151116010755	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1151116010756	DNA binding site [nucleotide binding]
1151116010757	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1151116010758	active site
1151116010759	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1151116010760	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1151116010761	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1151116010762	active site
1151116010763	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1151116010764	catalytic triad [active]
1151116010765	dimer interface [polypeptide binding]; other site
1151116010766	ammonium transporter; Provisional; Region: PRK10666
1151116010767	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1151116010768	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1151116010769	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1151116010770	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1151116010771	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1151116010772	Walker A/P-loop; other site
1151116010773	ATP binding site [chemical binding]; other site
1151116010774	Q-loop/lid; other site
1151116010775	ABC transporter signature motif; other site
1151116010776	Walker B; other site
1151116010777	D-loop; other site
1151116010778	H-loop/switch region; other site
1151116010779	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1151116010780	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1151116010781	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116010782	Walker A/P-loop; other site
1151116010783	ATP binding site [chemical binding]; other site
1151116010784	Q-loop/lid; other site
1151116010785	ABC transporter signature motif; other site
1151116010786	Walker B; other site
1151116010787	D-loop; other site
1151116010788	H-loop/switch region; other site
1151116010789	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1151116010790	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116010791	putative DNA binding site [nucleotide binding]; other site
1151116010792	putative Zn2+ binding site [ion binding]; other site
1151116010793	AsnC family; Region: AsnC_trans_reg; pfam01037
1151116010794	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1151116010795	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1151116010796	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116010797	catalytic residue [active]
1151116010798	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1151116010799	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116010800	active site
1151116010801	motif I; other site
1151116010802	motif II; other site
1151116010803	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1151116010804	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1151116010805	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1151116010806	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1151116010807	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1151116010808	Ligand Binding Site [chemical binding]; other site
1151116010809	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1151116010810	active site
1151116010811	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1151116010812	periplasmic folding chaperone; Provisional; Region: PRK10788
1151116010813	SurA N-terminal domain; Region: SurA_N_3; cl07813
1151116010814	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1151116010815	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1151116010816	IHF dimer interface [polypeptide binding]; other site
1151116010817	IHF - DNA interface [nucleotide binding]; other site
1151116010818	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1151116010819	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1151116010820	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1151116010821	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116010822	Walker A motif; other site
1151116010823	ATP binding site [chemical binding]; other site
1151116010824	Walker B motif; other site
1151116010825	arginine finger; other site
1151116010826	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1151116010827	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1151116010828	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1151116010829	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116010830	Walker A motif; other site
1151116010831	ATP binding site [chemical binding]; other site
1151116010832	Walker B motif; other site
1151116010833	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1151116010834	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1151116010835	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1151116010836	oligomer interface [polypeptide binding]; other site
1151116010837	active site residues [active]
1151116010838	trigger factor; Provisional; Region: tig; PRK01490
1151116010839	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1151116010840	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1151116010841	transcriptional regulator BolA; Provisional; Region: PRK11628
1151116010842	hypothetical protein; Provisional; Region: PRK11627
1151116010843	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1151116010844	Acetyl-coenzyme A transporter 1; Region: Acatn; pfam13000
1151116010845	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116010846	putative substrate translocation pore; other site
1151116010847	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1151116010848	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1151116010849	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1151116010850	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1151116010851	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1151116010852	D-pathway; other site
1151116010853	Putative ubiquinol binding site [chemical binding]; other site
1151116010854	Low-spin heme (heme b) binding site [chemical binding]; other site
1151116010855	Putative water exit pathway; other site
1151116010856	Binuclear center (heme o3/CuB) [ion binding]; other site
1151116010857	K-pathway; other site
1151116010858	Putative proton exit pathway; other site
1151116010859	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1151116010860	Subunit I/III interface [polypeptide binding]; other site
1151116010861	Subunit III/IV interface [polypeptide binding]; other site
1151116010862	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1151116010863	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1151116010864	UbiA prenyltransferase family; Region: UbiA; pfam01040
1151116010865	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116010866	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116010867	putative substrate translocation pore; other site
1151116010868	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1151116010869	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1151116010870	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1151116010871	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1151116010872	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1151116010873	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1151116010874	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1151116010875	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1151116010876	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1151116010877	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1151116010878	conserved cys residue [active]
1151116010879	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1151116010880	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1151116010881	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1151116010882	Ligand Binding Site [chemical binding]; other site
1151116010883	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1151116010884	active site residue [active]
1151116010885	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1151116010886	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1151116010887	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1151116010888	substrate binding pocket [chemical binding]; other site
1151116010889	chain length determination region; other site
1151116010890	substrate-Mg2+ binding site; other site
1151116010891	catalytic residues [active]
1151116010892	aspartate-rich region 1; other site
1151116010893	active site lid residues [active]
1151116010894	aspartate-rich region 2; other site
1151116010895	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1151116010896	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1151116010897	TPP-binding site; other site
1151116010898	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1151116010899	PYR/PP interface [polypeptide binding]; other site
1151116010900	dimer interface [polypeptide binding]; other site
1151116010901	TPP binding site [chemical binding]; other site
1151116010902	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1151116010903	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116010904	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116010905	active site
1151116010906	catalytic tetrad [active]
1151116010907	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1151116010908	tetramer interfaces [polypeptide binding]; other site
1151116010909	binuclear metal-binding site [ion binding]; other site
1151116010910	thiamine monophosphate kinase; Provisional; Region: PRK05731
1151116010911	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1151116010912	ATP binding site [chemical binding]; other site
1151116010913	dimerization interface [polypeptide binding]; other site
1151116010914	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1151116010915	putative RNA binding site [nucleotide binding]; other site
1151116010916	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1151116010917	homopentamer interface [polypeptide binding]; other site
1151116010918	active site
1151116010919	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1151116010920	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1151116010921	catalytic motif [active]
1151116010922	Zn binding site [ion binding]; other site
1151116010923	RibD C-terminal domain; Region: RibD_C; cl17279
1151116010924	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1151116010925	ATP cone domain; Region: ATP-cone; pfam03477
1151116010926	hypothetical protein; Provisional; Region: PRK11530
1151116010927	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1151116010928	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1151116010929	Protein export membrane protein; Region: SecD_SecF; pfam02355
1151116010930	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1151116010931	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1151116010932	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1151116010933	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1151116010934	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1151116010935	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1151116010936	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1151116010937	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1151116010938	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1151116010939	Protein of unknown function, DUF479; Region: DUF479; cl01203
1151116010940	peroxidase; Provisional; Region: PRK15000
1151116010941	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1151116010942	dimer interface [polypeptide binding]; other site
1151116010943	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1151116010944	catalytic triad [active]
1151116010945	peroxidatic and resolving cysteines [active]
1151116010946	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1151116010947	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1151116010948	putative proline-specific permease; Provisional; Region: proY; PRK10580
1151116010949	Spore germination protein; Region: Spore_permease; cl17796
1151116010950	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
1151116010951	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1151116010952	substrate binding site [chemical binding]; other site
1151116010953	THF binding site; other site
1151116010954	zinc-binding site [ion binding]; other site
1151116010955	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1151116010956	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116010957	non-specific DNA binding site [nucleotide binding]; other site
1151116010958	salt bridge; other site
1151116010959	sequence-specific DNA binding site [nucleotide binding]; other site
1151116010960	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1151116010961	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1151116010962	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116010963	putative active site [active]
1151116010964	heme pocket [chemical binding]; other site
1151116010965	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116010966	dimer interface [polypeptide binding]; other site
1151116010967	phosphorylation site [posttranslational modification]
1151116010968	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116010969	ATP binding site [chemical binding]; other site
1151116010970	Mg2+ binding site [ion binding]; other site
1151116010971	G-X-G motif; other site
1151116010972	transcriptional regulator PhoB; Provisional; Region: PRK10161
1151116010973	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116010974	active site
1151116010975	phosphorylation site [posttranslational modification]
1151116010976	intermolecular recognition site; other site
1151116010977	dimerization interface [polypeptide binding]; other site
1151116010978	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116010979	DNA binding site [nucleotide binding]
1151116010980	exonuclease subunit SbcD; Provisional; Region: PRK10966
1151116010981	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1151116010982	active site
1151116010983	metal binding site [ion binding]; metal-binding site
1151116010984	DNA binding site [nucleotide binding]
1151116010985	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1151116010986	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116010987	AAA domain; Region: AAA_23; pfam13476
1151116010988	Walker A/P-loop; other site
1151116010989	ATP binding site [chemical binding]; other site
1151116010990	Q-loop/lid; other site
1151116010991	exonuclease subunit SbcC; Provisional; Region: PRK10246
1151116010992	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116010993	ABC transporter signature motif; other site
1151116010994	Walker B; other site
1151116010995	D-loop; other site
1151116010996	H-loop/switch region; other site
1151116010997	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116010998	Walker B; other site
1151116010999	D-loop; other site
1151116011000	H-loop/switch region; other site
1151116011001	HNH endonuclease; Region: HNH_2; pfam13391
1151116011002	fructokinase; Reviewed; Region: PRK09557
1151116011003	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116011004	nucleotide binding site [chemical binding]; other site
1151116011005	recombination associated protein; Reviewed; Region: rdgC; PRK00321
1151116011006	Protein of unknown function (DUF1255); Region: DUF1255; cl01202
1151116011007	hypothetical protein; Provisional; Region: PRK10481
1151116011008	Protein of unknown function (DUF1177); Region: DUF1177; pfam06675
1151116011009	OPT oligopeptide transporter protein; Region: OPT; cl14607
1151116011010	OPT oligopeptide transporter protein; Region: OPT; cl14607
1151116011011	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1151116011012	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116011013	putative DNA binding site [nucleotide binding]; other site
1151116011014	putative Zn2+ binding site [ion binding]; other site
1151116011015	Bacterial transcriptional regulator; Region: IclR; pfam01614
1151116011016	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1151116011017	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1151116011018	ADP binding site [chemical binding]; other site
1151116011019	magnesium binding site [ion binding]; other site
1151116011020	putative shikimate binding site; other site
1151116011021	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1151116011022	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116011023	Protein of unknown function (DUF808); Region: DUF808; pfam05661
1151116011024	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1151116011025	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116011026	S-adenosylmethionine binding site [chemical binding]; other site
1151116011027	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116011028	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1151116011029	salt bridge; other site
1151116011030	non-specific DNA binding site [nucleotide binding]; other site
1151116011031	sequence-specific DNA binding site [nucleotide binding]; other site
1151116011032	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116011033	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116011034	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116011035	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1151116011036	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1151116011037	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1151116011038	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1151116011039	active site residue [active]
1151116011040	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1151116011041	active site residue [active]
1151116011042	ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221
1151116011043	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
1151116011044	Fatty acid desaturase protein family subgroup, a delta-12 acyl-lipid desaturase-like, DesA-like, yet uncharacterized subgroup of membrane fatty acid desaturase proteins found in alpha-, beta-, and gamma-proteobacteria. Sequences of this domain family...; Region: DesA_FADS-like; cd03509
1151116011045	putative di-iron ligands [ion binding]; other site
1151116011046	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1151116011047	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1151116011048	catalytic core [active]
1151116011049	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1151116011050	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1151116011051	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1151116011052	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1151116011053	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1151116011054	dimerization interface [polypeptide binding]; other site
1151116011055	ATP binding site [chemical binding]; other site
1151116011056	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1151116011057	dimerization interface [polypeptide binding]; other site
1151116011058	ATP binding site [chemical binding]; other site
1151116011059	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1151116011060	putative active site [active]
1151116011061	catalytic triad [active]
1151116011062	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1151116011063	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116011064	substrate binding pocket [chemical binding]; other site
1151116011065	membrane-bound complex binding site; other site
1151116011066	hinge residues; other site
1151116011067	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116011068	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116011069	catalytic residue [active]
1151116011070	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1151116011071	nucleoside/Zn binding site; other site
1151116011072	dimer interface [polypeptide binding]; other site
1151116011073	catalytic motif [active]
1151116011074	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1151116011075	hypothetical protein; Provisional; Region: PRK11590
1151116011076	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1151116011077	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116011078	active site turn [active]
1151116011079	phosphorylation site [posttranslational modification]
1151116011080	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116011081	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1151116011082	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1151116011083	putative active site [active]
1151116011084	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1151116011085	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116011086	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1151116011087	putative active site [active]
1151116011088	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1151116011089	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1151116011090	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1151116011091	active site
1151116011092	hydrophilic channel; other site
1151116011093	dimerization interface [polypeptide binding]; other site
1151116011094	catalytic residues [active]
1151116011095	active site lid [active]
1151116011096	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1151116011097	Recombination protein O N terminal; Region: RecO_N; pfam11967
1151116011098	Recombination protein O C terminal; Region: RecO_C; pfam02565
1151116011099	GTPase Era; Reviewed; Region: era; PRK00089
1151116011100	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1151116011101	G1 box; other site
1151116011102	GTP/Mg2+ binding site [chemical binding]; other site
1151116011103	Switch I region; other site
1151116011104	G2 box; other site
1151116011105	Switch II region; other site
1151116011106	G3 box; other site
1151116011107	G4 box; other site
1151116011108	G5 box; other site
1151116011109	KH domain; Region: KH_2; pfam07650
1151116011110	ribonuclease III; Reviewed; Region: rnc; PRK00102
1151116011111	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1151116011112	dimerization interface [polypeptide binding]; other site
1151116011113	active site
1151116011114	metal binding site [ion binding]; metal-binding site
1151116011115	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1151116011116	dsRNA binding site [nucleotide binding]; other site
1151116011117	signal peptidase I; Provisional; Region: PRK10861
1151116011118	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1151116011119	Catalytic site [active]
1151116011120	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1151116011121	GTP-binding protein LepA; Provisional; Region: PRK05433
1151116011122	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1151116011123	G1 box; other site
1151116011124	putative GEF interaction site [polypeptide binding]; other site
1151116011125	GTP/Mg2+ binding site [chemical binding]; other site
1151116011126	Switch I region; other site
1151116011127	G2 box; other site
1151116011128	G3 box; other site
1151116011129	Switch II region; other site
1151116011130	G4 box; other site
1151116011131	G5 box; other site
1151116011132	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1151116011133	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1151116011134	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1151116011135	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; cl01178
1151116011136	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1151116011137	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1151116011138	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1151116011139	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1151116011140	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1151116011141	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1151116011142	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1151116011143	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1151116011144	DNA binding residues [nucleotide binding]
1151116011145	L-aspartate oxidase; Provisional; Region: PRK09077
1151116011146	L-aspartate oxidase; Provisional; Region: PRK06175
1151116011147	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1151116011148	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1151116011149	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116011150	S-adenosylmethionine binding site [chemical binding]; other site
1151116011151	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1151116011152	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1151116011153	ATP binding site [chemical binding]; other site
1151116011154	Mg++ binding site [ion binding]; other site
1151116011155	motif III; other site
1151116011156	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116011157	nucleotide binding region [chemical binding]; other site
1151116011158	ATP-binding site [chemical binding]; other site
1151116011159	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1151116011160	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1151116011161	ligand binding site [chemical binding]; other site
1151116011162	active site
1151116011163	UGI interface [polypeptide binding]; other site
1151116011164	catalytic site [active]
1151116011165	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1151116011166	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1151116011167	dimer interface [polypeptide binding]; other site
1151116011168	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1151116011169	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1151116011170	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1151116011171	recombination and repair protein; Provisional; Region: PRK10869
1151116011172	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1151116011173	Walker A/P-loop; other site
1151116011174	ATP binding site [chemical binding]; other site
1151116011175	Q-loop/lid; other site
1151116011176	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1151116011177	Q-loop/lid; other site
1151116011178	ABC transporter signature motif; other site
1151116011179	Walker B; other site
1151116011180	D-loop; other site
1151116011181	H-loop/switch region; other site
1151116011182	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1151116011183	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1151116011184	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116011185	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116011186	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116011187	hypothetical protein; Validated; Region: PRK01777
1151116011188	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1151116011189	putative coenzyme Q binding site [chemical binding]; other site
1151116011190	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1151116011191	SmpB-tmRNA interface; other site
1151116011192	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1151116011193	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116011194	dimerization interface [polypeptide binding]; other site
1151116011195	putative DNA binding site [nucleotide binding]; other site
1151116011196	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1151116011197	putative Zn2+ binding site [ion binding]; other site
1151116011198	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1151116011199	active site residue [active]
1151116011200	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1151116011201	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1151116011202	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1151116011203	Glyco_18 domain; Region: Glyco_18; smart00636
1151116011204	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1151116011205	active site
1151116011206	Beta/Gamma crystallin; Region: Crystall; cl02528
1151116011207	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1151116011208	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116011209	substrate binding pocket [chemical binding]; other site
1151116011210	membrane-bound complex binding site; other site
1151116011211	hinge residues; other site
1151116011212	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1151116011213	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1151116011214	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1151116011215	Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; cl09211
1151116011216	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1151116011217	active site
1151116011218	phosphorylation site [posttranslational modification]
1151116011219	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1151116011220	active site
1151116011221	P-loop; other site
1151116011222	phosphorylation site [posttranslational modification]
1151116011223	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1151116011224	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1151116011225	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1151116011226	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1151116011227	putative NAD(P) binding site [chemical binding]; other site
1151116011228	catalytic Zn binding site [ion binding]; other site
1151116011229	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1151116011230	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1151116011231	intersubunit interface [polypeptide binding]; other site
1151116011232	active site
1151116011233	zinc binding site [ion binding]; other site
1151116011234	Na+ binding site [ion binding]; other site
1151116011235	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1151116011236	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1151116011237	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1151116011238	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116011239	Coenzyme A binding pocket [chemical binding]; other site
1151116011240	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1151116011241	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1151116011242	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116011243	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1151116011244	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1151116011245	DNA binding site [nucleotide binding]
1151116011246	active site
1151116011247	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1151116011248	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116011249	Coenzyme A binding pocket [chemical binding]; other site
1151116011250	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1151116011251	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1151116011252	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116011253	non-specific DNA binding site [nucleotide binding]; other site
1151116011254	salt bridge; other site
1151116011255	sequence-specific DNA binding site [nucleotide binding]; other site
1151116011256	Cupin domain; Region: Cupin_2; pfam07883
1151116011257	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
1151116011258	Predicted aminopeptidases [General function prediction only]; Region: Iap; COG2234
1151116011259	PA/protease or protease-like domain interface [polypeptide binding]; other site
1151116011260	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1151116011261	Peptidase family M28; Region: Peptidase_M28; pfam04389
1151116011262	metal binding site [ion binding]; metal-binding site
1151116011263	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1151116011264	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116011265	substrate binding pocket [chemical binding]; other site
1151116011266	membrane-bound complex binding site; other site
1151116011267	hinge residues; other site
1151116011268	M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672
1151116011269	amidohydrolase; Region: amidohydrolases; TIGR01891
1151116011270	metal binding site [ion binding]; metal-binding site
1151116011271	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116011272	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116011273	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116011274	dimerization interface [polypeptide binding]; other site
1151116011275	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1151116011276	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
1151116011277	L-lysine 6-monooxygenase (NADPH-requiring); Region: K_oxygenase; pfam13434
1151116011278	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1151116011279	hemolysin; Provisional; Region: PRK15087
1151116011280	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1151116011281	HD domain; Region: HD_3; pfam13023
1151116011282	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1151116011283	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1151116011284	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1151116011285	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1151116011286	Walker A/P-loop; other site
1151116011287	ATP binding site [chemical binding]; other site
1151116011288	Q-loop/lid; other site
1151116011289	ABC transporter signature motif; other site
1151116011290	Walker B; other site
1151116011291	D-loop; other site
1151116011292	H-loop/switch region; other site
1151116011293	TOBE domain; Region: TOBE_2; pfam08402
1151116011294	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1151116011295	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1151116011296	active site
1151116011297	metal binding site [ion binding]; metal-binding site
1151116011298	hexamer interface [polypeptide binding]; other site
1151116011299	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116011300	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116011301	dimer interface [polypeptide binding]; other site
1151116011302	conserved gate region; other site
1151116011303	putative PBP binding loops; other site
1151116011304	ABC-ATPase subunit interface; other site
1151116011305	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116011306	dimer interface [polypeptide binding]; other site
1151116011307	conserved gate region; other site
1151116011308	putative PBP binding loops; other site
1151116011309	ABC-ATPase subunit interface; other site
1151116011310	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116011311	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1151116011312	substrate binding site [chemical binding]; other site
1151116011313	dimer interface [polypeptide binding]; other site
1151116011314	ATP binding site [chemical binding]; other site
1151116011315	D-allose kinase; Provisional; Region: PRK09698
1151116011316	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116011317	nucleotide binding site [chemical binding]; other site
1151116011318	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1151116011319	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1151116011320	substrate binding site [chemical binding]; other site
1151116011321	hexamer interface [polypeptide binding]; other site
1151116011322	metal binding site [ion binding]; metal-binding site
1151116011323	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116011324	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116011325	TM-ABC transporter signature motif; other site
1151116011326	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116011327	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116011328	TM-ABC transporter signature motif; other site
1151116011329	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1151116011330	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116011331	Walker A/P-loop; other site
1151116011332	ATP binding site [chemical binding]; other site
1151116011333	Q-loop/lid; other site
1151116011334	ABC transporter signature motif; other site
1151116011335	Walker B; other site
1151116011336	D-loop; other site
1151116011337	H-loop/switch region; other site
1151116011338	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116011339	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1151116011340	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1151116011341	ligand binding site [chemical binding]; other site
1151116011342	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1151116011343	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1151116011344	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1151116011345	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
1151116011346	classical (c) SDRs; Region: SDR_c; cd05233
1151116011347	NAD(P) binding site [chemical binding]; other site
1151116011348	active site
1151116011349	glycine dehydrogenase; Provisional; Region: PRK05367
1151116011350	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1151116011351	tetramer interface [polypeptide binding]; other site
1151116011352	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116011353	catalytic residue [active]
1151116011354	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1151116011355	tetramer interface [polypeptide binding]; other site
1151116011356	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116011357	catalytic residue [active]
1151116011358	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1151116011359	lipoyl attachment site [posttranslational modification]; other site
1151116011360	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1151116011361	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1151116011362	oxidoreductase; Provisional; Region: PRK08013
1151116011363	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1151116011364	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1151116011365	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
1151116011366	proline aminopeptidase P II; Provisional; Region: PRK10879
1151116011367	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1151116011368	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1151116011369	active site
1151116011370	hypothetical protein; Reviewed; Region: PRK01736
1151116011371	Z-ring-associated protein; Provisional; Region: PRK10972
1151116011372	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1151116011373	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
1151116011374	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1151116011375	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1151116011376	L-serine binding site [chemical binding]; other site
1151116011377	ACT domain interface; other site
1151116011378	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1151116011379	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
1151116011380	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1151116011381	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1151116011382	ligand binding site [chemical binding]; other site
1151116011383	NAD binding site [chemical binding]; other site
1151116011384	tetramer interface [polypeptide binding]; other site
1151116011385	catalytic site [active]
1151116011386	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1151116011387	L-serine binding site [chemical binding]; other site
1151116011388	ACT domain interface; other site
1151116011389	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1151116011390	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1151116011391	active site
1151116011392	dimer interface [polypeptide binding]; other site
1151116011393	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1151116011394	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116011395	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1151116011396	putative dimerization interface [polypeptide binding]; other site
1151116011397	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116011398	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116011399	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1151116011400	putative effector binding pocket; other site
1151116011401	putative dimerization interface [polypeptide binding]; other site
1151116011402	short chain dehydrogenase; Provisional; Region: PRK06482
1151116011403	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1151116011404	NADP binding site [chemical binding]; other site
1151116011405	active site
1151116011406	steroid binding site; other site
1151116011407	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1151116011408	oxidative stress defense protein; Provisional; Region: PRK11087
1151116011409	arginine exporter protein; Provisional; Region: PRK09304
1151116011410	mechanosensitive channel MscS; Provisional; Region: PRK10334
1151116011411	Conserved TM helix; Region: TM_helix; pfam05552
1151116011412	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1151116011413	galactoside permease; Reviewed; Region: lacY; PRK09528
1151116011414	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116011415	putative substrate translocation pore; other site
1151116011416	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
1151116011417	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1151116011418	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1151116011419	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1151116011420	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
1151116011421	lac repressor; Reviewed; Region: lacI; PRK09526
1151116011422	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116011423	DNA binding site [nucleotide binding]
1151116011424	domain linker motif; other site
1151116011425	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
1151116011426	ligand binding site [chemical binding]; other site
1151116011427	dimerization interface (open form) [polypeptide binding]; other site
1151116011428	dimerization interface (closed form) [polypeptide binding]; other site
1151116011429	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1151116011430	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1151116011431	active site
1151116011432	intersubunit interface [polypeptide binding]; other site
1151116011433	zinc binding site [ion binding]; other site
1151116011434	Na+ binding site [ion binding]; other site
1151116011435	Phosphoglycerate kinase; Region: PGK; pfam00162
1151116011436	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1151116011437	substrate binding site [chemical binding]; other site
1151116011438	hinge regions; other site
1151116011439	ADP binding site [chemical binding]; other site
1151116011440	catalytic site [active]
1151116011441	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1151116011442	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1151116011443	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1151116011444	transketolase; Reviewed; Region: PRK12753
1151116011445	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1151116011446	TPP-binding site [chemical binding]; other site
1151116011447	dimer interface [polypeptide binding]; other site
1151116011448	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1151116011449	PYR/PP interface [polypeptide binding]; other site
1151116011450	dimer interface [polypeptide binding]; other site
1151116011451	TPP binding site [chemical binding]; other site
1151116011452	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1151116011453	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1151116011454	Fimbrial protein; Region: Fimbrial; cl01416
1151116011455	putative chaperone protein EcpD; Provisional; Region: PRK09926
1151116011456	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1151116011457	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1151116011458	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
1151116011459	PapC N-terminal domain; Region: PapC_N; pfam13954
1151116011460	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1151116011461	PapC C-terminal domain; Region: PapC_C; pfam13953
1151116011462	Fimbrial protein; Region: Fimbrial; cl01416
1151116011463	putative fimbrial protein StaE; Provisional; Region: PRK15263
1151116011464	Fimbrial protein; Region: Fimbrial; cl01416
1151116011465	Fimbrial protein; Region: Fimbrial; cl01416
1151116011466	arginine decarboxylase; Provisional; Region: PRK05354
1151116011467	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1151116011468	dimer interface [polypeptide binding]; other site
1151116011469	active site
1151116011470	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1151116011471	catalytic residues [active]
1151116011472	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1151116011473	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1151116011474	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1151116011475	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1151116011476	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1151116011477	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1151116011478	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; cl04524
1151116011479	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
1151116011480	CblD like pilus biogenesis initiator; Region: CblD; cl06460
1151116011481	CblD like pilus biogenesis initiator; Region: CblD; cl06460
1151116011482	putative fimbrial protein TcfA; Provisional; Region: PRK15308
1151116011483	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1151116011484	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116011485	putative substrate translocation pore; other site
1151116011486	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116011487	SprT-like family; Region: SprT-like; pfam10263
1151116011488	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1151116011489	DNA-specific endonuclease I; Provisional; Region: PRK15137
1151116011490	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1151116011491	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1151116011492	RNA methyltransferase, RsmE family; Region: TIGR00046
1151116011493	glutathione synthetase; Provisional; Region: PRK05246
1151116011494	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1151116011495	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1151116011496	hypothetical protein; Validated; Region: PRK00228
1151116011497	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1151116011498	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1151116011499	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1151116011500	Walker A motif; other site
1151116011501	ATP binding site [chemical binding]; other site
1151116011502	Walker B motif; other site
1151116011503	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1151116011504	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1151116011505	catalytic residue [active]
1151116011506	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1151116011507	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1151116011508	YGGT family; Region: YGGT; pfam02325
1151116011509	YGGT family; Region: YGGT; pfam02325
1151116011510	hypothetical protein; Validated; Region: PRK05090
1151116011511	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1151116011512	active site
1151116011513	dimerization interface [polypeptide binding]; other site
1151116011514	HemN family oxidoreductase; Provisional; Region: PRK05660
1151116011515	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116011516	FeS/SAM binding site; other site
1151116011517	HemN C-terminal domain; Region: HemN_C; pfam06969
1151116011518	hypothetical protein; Provisional; Region: PRK10626
1151116011519	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1151116011520	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1151116011521	glutaminase; Provisional; Region: PRK00971
1151116011522	hypothetical protein; Provisional; Region: PRK11702
1151116011523	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116011524	S-adenosylmethionine binding site [chemical binding]; other site
1151116011525	adenine DNA glycosylase; Provisional; Region: PRK10880
1151116011526	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1151116011527	minor groove reading motif; other site
1151116011528	helix-hairpin-helix signature motif; other site
1151116011529	substrate binding pocket [chemical binding]; other site
1151116011530	active site
1151116011531	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1151116011532	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1151116011533	DNA binding and oxoG recognition site [nucleotide binding]
1151116011534	oxidative damage protection protein; Provisional; Region: PRK05408
1151116011535	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1151116011536	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1151116011537	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116011538	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116011539	catalytic residue [active]
1151116011540	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1151116011541	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1151116011542	putative ADP-binding pocket [chemical binding]; other site
1151116011543	Pectate lyase; Region: Pec_lyase_C; cl01593
1151116011544	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1151116011545	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1151116011546	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
1151116011547	trimer interface [polypeptide binding]; other site
1151116011548	active site
1151116011549	substrate binding site [chemical binding]; other site
1151116011550	CoA binding site [chemical binding]; other site
1151116011551	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1151116011552	This family is most closely related to the GT1 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1); Region: GT1_CapH_like; cd03812
1151116011553	putative ADP-binding pocket [chemical binding]; other site
1151116011554	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1151116011555	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1151116011556	tyrosine kinase; Provisional; Region: PRK11519
1151116011557	Chain length determinant protein; Region: Wzz; pfam02706
1151116011558	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1151116011559	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1151116011560	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1151116011561	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1151116011562	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
1151116011563	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1151116011564	SLBB domain; Region: SLBB; pfam10531
1151116011565	SLBB domain; Region: SLBB; pfam10531
1151116011566	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1151116011567	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1151116011568	Mg++ binding site [ion binding]; other site
1151116011569	putative catalytic motif [active]
1151116011570	substrate binding site [chemical binding]; other site
1151116011571	ornithine decarboxylase; Provisional; Region: PRK13578
1151116011572	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1151116011573	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1151116011574	homodimer interface [polypeptide binding]; other site
1151116011575	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116011576	catalytic residue [active]
1151116011577	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1151116011578	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116011579	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116011580	putative substrate translocation pore; other site
1151116011581	Domain of unknown function (DUF386); Region: DUF386; cl01047
1151116011582	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1151116011583	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1151116011584	inhibitor site; inhibition site
1151116011585	active site
1151116011586	dimer interface [polypeptide binding]; other site
1151116011587	catalytic residue [active]
1151116011588	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1151116011589	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1151116011590	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116011591	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1151116011592	substrate binding site [chemical binding]; other site
1151116011593	dimer interface [polypeptide binding]; other site
1151116011594	ATP binding site [chemical binding]; other site
1151116011595	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1151116011596	putative catalytic site [active]
1151116011597	putative metal binding site [ion binding]; other site
1151116011598	putative phosphate binding site [ion binding]; other site
1151116011599	cardiolipin synthase 2; Provisional; Region: PRK11263
1151116011600	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1151116011601	putative active site [active]
1151116011602	catalytic site [active]
1151116011603	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1151116011604	putative active site [active]
1151116011605	catalytic site [active]
1151116011606	Predicted integral membrane protein [Function unknown]; Region: COG0392
1151116011607	manganese transport protein MntH; Reviewed; Region: PRK00701
1151116011608	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1151116011609	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1151116011610	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116011611	dimer interface [polypeptide binding]; other site
1151116011612	putative CheW interface [polypeptide binding]; other site
1151116011613	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1151116011614	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1151116011615	ligand binding site [chemical binding]; other site
1151116011616	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1151116011617	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1151116011618	NADP-binding site; other site
1151116011619	homotetramer interface [polypeptide binding]; other site
1151116011620	homodimer interface [polypeptide binding]; other site
1151116011621	active site
1151116011622	substrate binding site [chemical binding]; other site
1151116011623	This family is most closely related to the GT1 family of glycosyltransferases.  wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804
1151116011624	Glycosyltransferase Family 4; Region: Glyco_transf_4; pfam13439
1151116011625	putative ADP-binding pocket [chemical binding]; other site
1151116011626	phosphomannomutase CpsG; Provisional; Region: PRK15414
1151116011627	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1151116011628	active site
1151116011629	substrate binding site [chemical binding]; other site
1151116011630	metal binding site [ion binding]; metal-binding site
1151116011631	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1151116011632	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1151116011633	Substrate binding site; other site
1151116011634	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1151116011635	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1151116011636	active site
1151116011637	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1151116011638	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1151116011639	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
1151116011640	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1151116011641	putative ADP-binding pocket [chemical binding]; other site
1151116011642	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1151116011643	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1151116011644	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1151116011645	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1151116011646	This family is most closely related to the GT1 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II); Region: GT1_ExpE7_like; cd03823
1151116011647	tyrosine kinase; Provisional; Region: PRK11519
1151116011648	Chain length determinant protein; Region: Wzz; pfam02706
1151116011649	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1151116011650	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1151116011651	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1151116011652	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1151116011653	polysaccharide export protein Wza; Provisional; Region: PRK15078
1151116011654	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1151116011655	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1151116011656	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1151116011657	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1151116011658	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1151116011659	potential frameshift: common BLAST hit: gi|322834292|ref|YP_004214319.1| lipoprotein YmcC
1151116011660	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1151116011661	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1151116011662	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116011663	DNA binding residues [nucleotide binding]
1151116011664	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1151116011665	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1151116011666	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1151116011667	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1151116011668	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1151116011669	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1151116011670	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1151116011671	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116011672	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116011673	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1151116011674	Protein export membrane protein; Region: SecD_SecF; cl14618
1151116011675	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1151116011676	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1151116011677	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116011678	non-specific DNA binding site [nucleotide binding]; other site
1151116011679	salt bridge; other site
1151116011680	sequence-specific DNA binding site [nucleotide binding]; other site
1151116011681	Cupin domain; Region: Cupin_2; pfam07883
1151116011682	AzlC protein; Region: AzlC; cl00570
1151116011683	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1151116011684	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1151116011685	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1151116011686	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1151116011687	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116011688	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116011689	LysE type translocator; Region: LysE; pfam01810
1151116011690	Protein of unknown function (DUF1345); Region: DUF1345; pfam07077
1151116011691	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116011692	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116011693	substrate binding pocket [chemical binding]; other site
1151116011694	membrane-bound complex binding site; other site
1151116011695	hinge residues; other site
1151116011696	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1151116011697	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116011698	dimer interface [polypeptide binding]; other site
1151116011699	conserved gate region; other site
1151116011700	putative PBP binding loops; other site
1151116011701	ABC-ATPase subunit interface; other site
1151116011702	transaminase; Validated; Region: PRK07324
1151116011703	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116011704	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116011705	homodimer interface [polypeptide binding]; other site
1151116011706	catalytic residue [active]
1151116011707	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1151116011708	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
1151116011709	putative sugar binding site [chemical binding]; other site
1151116011710	catalytic residues [active]
1151116011711	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
1151116011712	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1151116011713	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1151116011714	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116011715	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116011716	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1151116011717	dimerization interface [polypeptide binding]; other site
1151116011718	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1151116011719	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1151116011720	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1151116011721	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1151116011722	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
1151116011723	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1151116011724	active site
1151116011725	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1151116011726	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1151116011727	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1151116011728	transcriptional regulator; Provisional; Region: PRK10632
1151116011729	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116011730	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_7; cd08476
1151116011731	putative effector binding pocket; other site
1151116011732	putative dimerization interface [polypeptide binding]; other site
1151116011733	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1151116011734	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116011735	putative substrate translocation pore; other site
1151116011736	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116011737	Spore Coat Protein U domain; Region: SCPU; pfam05229
1151116011738	Spore Coat Protein U domain; Region: SCPU; pfam05229
1151116011739	Spore Coat Protein U domain; Region: SCPU; pfam05229
1151116011740	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1151116011741	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1151116011742	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1151116011743	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1151116011744	PapC C-terminal domain; Region: PapC_C; pfam13953
1151116011745	Spore Coat Protein U domain; Region: SCPU; pfam05229
1151116011746	Uncharacterized secreted protein [Function unknown]; Region: COG5430
1151116011747	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1151116011748	DNA-binding site [nucleotide binding]; DNA binding site
1151116011749	RNA-binding motif; other site
1151116011750	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1151116011751	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
1151116011752	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1151116011753	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1151116011754	shikimate binding site; other site
1151116011755	NAD(P) binding site [chemical binding]; other site
1151116011756	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1151116011757	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1151116011758	active site
1151116011759	tetramer interface [polypeptide binding]; other site
1151116011760	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1151116011761	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1151116011762	active site
1151116011763	tetramer interface [polypeptide binding]; other site
1151116011764	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116011765	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116011766	putative substrate translocation pore; other site
1151116011767	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1151116011768	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1151116011769	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1151116011770	serine endoprotease; Provisional; Region: PRK10942
1151116011771	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1151116011772	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1151116011773	protein binding site [polypeptide binding]; other site
1151116011774	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1151116011775	protein binding site [polypeptide binding]; other site
1151116011776	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1151116011777	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1151116011778	Zn2+ binding site [ion binding]; other site
1151116011779	Mg2+ binding site [ion binding]; other site
1151116011780	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1151116011781	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1151116011782	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1151116011783	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1151116011784	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1151116011785	cobalamin binding residues [chemical binding]; other site
1151116011786	putative BtuC binding residues; other site
1151116011787	dimer interface [polypeptide binding]; other site
1151116011788	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1151116011789	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1151116011790	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1151116011791	Cl- selectivity filter; other site
1151116011792	Cl- binding residues [ion binding]; other site
1151116011793	pore gating glutamate residue; other site
1151116011794	dimer interface [polypeptide binding]; other site
1151116011795	H+/Cl- coupling transport residue; other site
1151116011796	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1151116011797	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1151116011798	inhibitor-cofactor binding pocket; inhibition site
1151116011799	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116011800	catalytic residue [active]
1151116011801	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1151116011802	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116011803	ABC-ATPase subunit  interface; other site
1151116011804	dimer interface [polypeptide binding]; other site
1151116011805	putative PBP binding regions; other site
1151116011806	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116011807	ABC-ATPase subunit  interface; other site
1151116011808	dimer interface [polypeptide binding]; other site
1151116011809	putative PBP binding regions; other site
1151116011810	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1151116011811	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1151116011812	siderophore binding site; other site
1151116011813	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1151116011814	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1151116011815	Walker A/P-loop; other site
1151116011816	ATP binding site [chemical binding]; other site
1151116011817	Q-loop/lid; other site
1151116011818	ABC transporter signature motif; other site
1151116011819	Walker B; other site
1151116011820	D-loop; other site
1151116011821	H-loop/switch region; other site
1151116011822	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1151116011823	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116011824	N-terminal plug; other site
1151116011825	ligand-binding site [chemical binding]; other site
1151116011826	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1151116011827	Transglycosylase; Region: Transgly; pfam00912
1151116011828	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1151116011829	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1151116011830	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116011831	ATP binding site [chemical binding]; other site
1151116011832	putative Mg++ binding site [ion binding]; other site
1151116011833	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116011834	nucleotide binding region [chemical binding]; other site
1151116011835	ATP-binding site [chemical binding]; other site
1151116011836	Helicase associated domain (HA2); Region: HA2; pfam04408
1151116011837	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1151116011838	2'-5' RNA ligase; Provisional; Region: PRK15124
1151116011839	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1151116011840	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1151116011841	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1151116011842	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1151116011843	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1151116011844	active site
1151116011845	nucleotide binding site [chemical binding]; other site
1151116011846	HIGH motif; other site
1151116011847	KMSKS motif; other site
1151116011848	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1151116011849	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1151116011850	active site
1151116011851	NTP binding site [chemical binding]; other site
1151116011852	metal binding triad [ion binding]; metal-binding site
1151116011853	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1151116011854	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1151116011855	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1151116011856	catalytic center binding site [active]
1151116011857	ATP binding site [chemical binding]; other site
1151116011858	sensor protein QseC; Provisional; Region: PRK10337
1151116011859	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116011860	dimer interface [polypeptide binding]; other site
1151116011861	phosphorylation site [posttranslational modification]
1151116011862	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116011863	ATP binding site [chemical binding]; other site
1151116011864	Mg2+ binding site [ion binding]; other site
1151116011865	G-X-G motif; other site
1151116011866	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1151116011867	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116011868	active site
1151116011869	phosphorylation site [posttranslational modification]
1151116011870	intermolecular recognition site; other site
1151116011871	dimerization interface [polypeptide binding]; other site
1151116011872	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116011873	DNA binding site [nucleotide binding]
1151116011874	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1151116011875	oligomerization interface [polypeptide binding]; other site
1151116011876	active site
1151116011877	metal binding site [ion binding]; metal-binding site
1151116011878	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1151116011879	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1151116011880	active site
1151116011881	ATP-binding site [chemical binding]; other site
1151116011882	pantoate-binding site; other site
1151116011883	HXXH motif; other site
1151116011884	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1151116011885	tetramerization interface [polypeptide binding]; other site
1151116011886	active site
1151116011887	inner membrane transport permease; Provisional; Region: PRK15066
1151116011888	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1151116011889	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1151116011890	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1151116011891	Walker A/P-loop; other site
1151116011892	ATP binding site [chemical binding]; other site
1151116011893	Q-loop/lid; other site
1151116011894	ABC transporter signature motif; other site
1151116011895	Walker B; other site
1151116011896	D-loop; other site
1151116011897	H-loop/switch region; other site
1151116011898	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1151116011899	active site clefts [active]
1151116011900	zinc binding site [ion binding]; other site
1151116011901	dimer interface [polypeptide binding]; other site
1151116011902	integrase; Provisional; Region: int; PHA02601
1151116011903	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1151116011904	dimer interface [polypeptide binding]; other site
1151116011905	active site
1151116011906	catalytic residues [active]
1151116011907	Int/Topo IB signature motif; other site
1151116011908	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1151116011909	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116011910	non-specific DNA binding site [nucleotide binding]; other site
1151116011911	salt bridge; other site
1151116011912	sequence-specific DNA binding site [nucleotide binding]; other site
1151116011913	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
1151116011914	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
1151116011915	A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; cl17448
1151116011916	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1151116011917	DksA-like zinc finger domain containing protein; Region: PHA00080
1151116011918	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1151116011919	Protein of unknown function (DUF2806); Region: DUF2806; cl12560
1151116011920	portal vertex protein; Provisional; Region: Q; PHA02536
1151116011921	Phage portal protein; Region: Phage_portal; pfam04860
1151116011922	terminase ATPase subunit; Provisional; Region: P; PHA02535
1151116011923	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1151116011924	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
1151116011925	capsid protein; Provisional; Region: N; PHA02538
1151116011926	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1151116011927	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1151116011928	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1151116011929	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1151116011930	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1151116011931	catalytic residues [active]
1151116011932	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1151116011933	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1151116011934	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1151116011935	Uncharacterized conserved protein [Function unknown]; Region: COG1432
1151116011936	Uncharacterized subfamily of N-terminal LabA-like domains; Region: LabA_like_N_1; cd11297
1151116011937	putative metal binding site [ion binding]; other site
1151116011938	C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146
1151116011939	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1151116011940	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1151116011941	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1151116011942	baseplate assembly protein; Provisional; Region: J; PHA02568
1151116011943	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1151116011944	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1151116011945	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1151116011946	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1151116011947	major tail sheath protein; Provisional; Region: FI; PHA02560
1151116011948	major tail tube protein; Provisional; Region: FII; PHA02600
1151116011949	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1151116011950	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1151116011951	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1151116011952	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1151116011953	potential frameshift: common BLAST hit: gi|322831331|ref|YP_004211358.1| D protein bacteriophage 186 and P2
1151116011954	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1151116011955	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1151116011956	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1151116011957	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
1151116011958	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1151116011959	active site
1151116011960	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1151116011961	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1151116011962	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1151116011963	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1151116011964	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1151116011965	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1151116011966	putative NAD(P) binding site [chemical binding]; other site
1151116011967	active site
1151116011968	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; cl01516
1151116011969	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
1151116011970	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1151116011971	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1151116011972	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
1151116011973	multicopper oxidase; Provisional; Region: PRK10965
1151116011974	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1151116011975	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1151116011976	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1151116011977	spermidine synthase; Provisional; Region: PRK00811
1151116011978	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116011979	S-adenosylmethionine binding site [chemical binding]; other site
1151116011980	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1151116011981	aromatic amino acid exporter; Provisional; Region: PRK11689
1151116011982	EamA-like transporter family; Region: EamA; pfam00892
1151116011983	hypothetical protein; Provisional; Region: PRK05248
1151116011984	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1151116011985	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1151116011986	substrate binding site [chemical binding]; other site
1151116011987	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1151116011988	substrate binding site [chemical binding]; other site
1151116011989	ligand binding site [chemical binding]; other site
1151116011990	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1151116011991	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1151116011992	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
1151116011993	hypothetical protein; Provisional; Region: PRK11622
1151116011994	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1151116011995	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116011996	dimer interface [polypeptide binding]; other site
1151116011997	conserved gate region; other site
1151116011998	putative PBP binding loops; other site
1151116011999	ABC-ATPase subunit interface; other site
1151116012000	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116012001	dimer interface [polypeptide binding]; other site
1151116012002	conserved gate region; other site
1151116012003	putative PBP binding loops; other site
1151116012004	ABC-ATPase subunit interface; other site
1151116012005	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1151116012006	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116012007	Walker A/P-loop; other site
1151116012008	ATP binding site [chemical binding]; other site
1151116012009	Q-loop/lid; other site
1151116012010	ABC transporter signature motif; other site
1151116012011	Walker B; other site
1151116012012	D-loop; other site
1151116012013	H-loop/switch region; other site
1151116012014	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1151116012015	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1151116012016	active site
1151116012017	catalytic site [active]
1151116012018	MarR family; Region: MarR_2; pfam12802
1151116012019	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1151116012020	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116012021	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1151116012022	active site
1151116012023	catalytic site [active]
1151116012024	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1151116012025	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1151116012026	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1151116012027	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1151116012028	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1151116012029	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1151116012030	E3 interaction surface; other site
1151116012031	lipoyl attachment site [posttranslational modification]; other site
1151116012032	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1151116012033	E3 interaction surface; other site
1151116012034	lipoyl attachment site [posttranslational modification]; other site
1151116012035	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1151116012036	E3 interaction surface; other site
1151116012037	lipoyl attachment site [posttranslational modification]; other site
1151116012038	e3 binding domain; Region: E3_binding; pfam02817
1151116012039	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1151116012040	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1151116012041	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1151116012042	dimer interface [polypeptide binding]; other site
1151116012043	TPP-binding site [chemical binding]; other site
1151116012044	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1151116012045	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116012046	DNA-binding site [nucleotide binding]; DNA binding site
1151116012047	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1151116012048	aromatic amino acid transporter; Provisional; Region: PRK10238
1151116012049	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1151116012050	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116012051	putative substrate translocation pore; other site
1151116012052	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1151116012053	active site
1151116012054	regulatory protein AmpE; Provisional; Region: PRK10987
1151116012055	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1151116012056	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1151116012057	amidase catalytic site [active]
1151116012058	Zn binding residues [ion binding]; other site
1151116012059	substrate binding site [chemical binding]; other site
1151116012060	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1151116012061	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1151116012062	dimerization interface [polypeptide binding]; other site
1151116012063	active site
1151116012064	putative major pilin subunit; Provisional; Region: PRK10574
1151116012065	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1151116012066	hypothetical protein; Provisional; Region: PRK10436
1151116012067	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1151116012068	Walker A motif; other site
1151116012069	ATP binding site [chemical binding]; other site
1151116012070	Walker B motif; other site
1151116012071	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1151116012072	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1151116012073	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1151116012074	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1151116012075	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1151116012076	active site
1151116012077	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1151116012078	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1151116012079	CoA-binding site [chemical binding]; other site
1151116012080	ATP-binding [chemical binding]; other site
1151116012081	hypothetical protein; Provisional; Region: PRK05287
1151116012082	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1151116012083	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116012084	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116012085	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116012086	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1151116012087	active site
1151116012088	8-oxo-dGMP binding site [chemical binding]; other site
1151116012089	nudix motif; other site
1151116012090	metal binding site [ion binding]; metal-binding site
1151116012091	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1151116012092	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1151116012093	SEC-C motif; Region: SEC-C; pfam02810
1151116012094	SecA regulator SecM; Provisional; Region: PRK02943
1151116012095	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4701
1151116012096	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1151116012097	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1151116012098	cell division protein FtsZ; Validated; Region: PRK09330
1151116012099	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1151116012100	nucleotide binding site [chemical binding]; other site
1151116012101	SulA interaction site; other site
1151116012102	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1151116012103	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1151116012104	Cell division protein FtsA; Region: FtsA; pfam14450
1151116012105	cell division protein FtsQ; Provisional; Region: PRK10775
1151116012106	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1151116012107	Cell division protein FtsQ; Region: FtsQ; pfam03799
1151116012108	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1151116012109	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1151116012110	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1151116012111	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1151116012112	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1151116012113	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1151116012114	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1151116012115	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1151116012116	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1151116012117	active site
1151116012118	homodimer interface [polypeptide binding]; other site
1151116012119	cell division protein FtsW; Provisional; Region: PRK10774
1151116012120	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1151116012121	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1151116012122	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1151116012123	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1151116012124	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1151116012125	Mg++ binding site [ion binding]; other site
1151116012126	putative catalytic motif [active]
1151116012127	putative substrate binding site [chemical binding]; other site
1151116012128	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1151116012129	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1151116012130	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1151116012131	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1151116012132	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1151116012133	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1151116012134	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1151116012135	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1151116012136	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1151116012137	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1151116012138	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1151116012139	cell division protein FtsL; Provisional; Region: PRK10772
1151116012140	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1151116012141	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1151116012142	cell division protein MraZ; Reviewed; Region: PRK00326
1151116012143	MraZ protein; Region: MraZ; pfam02381
1151116012144	MraZ protein; Region: MraZ; pfam02381
1151116012145	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1151116012146	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116012147	DNA binding site [nucleotide binding]
1151116012148	domain linker motif; other site
1151116012149	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1151116012150	dimerization interface [polypeptide binding]; other site
1151116012151	ligand binding site [chemical binding]; other site
1151116012152	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1151116012153	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1151116012154	putative valine binding site [chemical binding]; other site
1151116012155	dimer interface [polypeptide binding]; other site
1151116012156	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1151116012157	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1151116012158	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1151116012159	PYR/PP interface [polypeptide binding]; other site
1151116012160	dimer interface [polypeptide binding]; other site
1151116012161	TPP binding site [chemical binding]; other site
1151116012162	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1151116012163	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1151116012164	TPP-binding site [chemical binding]; other site
1151116012165	dimer interface [polypeptide binding]; other site
1151116012166	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1151116012167	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1151116012168	acyl-activating enzyme (AAE) consensus motif; other site
1151116012169	putative AMP binding site [chemical binding]; other site
1151116012170	putative active site [active]
1151116012171	putative CoA binding site [chemical binding]; other site
1151116012172	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1151116012173	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116012174	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1151116012175	putative substrate binding pocket [chemical binding]; other site
1151116012176	putative dimerization interface [polypeptide binding]; other site
1151116012177	2-isopropylmalate synthase; Validated; Region: PRK00915
1151116012178	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1151116012179	active site
1151116012180	catalytic residues [active]
1151116012181	metal binding site [ion binding]; metal-binding site
1151116012182	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1151116012183	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1151116012184	tartrate dehydrogenase; Region: TTC; TIGR02089
1151116012185	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1151116012186	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1151116012187	substrate binding site [chemical binding]; other site
1151116012188	ligand binding site [chemical binding]; other site
1151116012189	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1151116012190	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1151116012191	substrate binding site [chemical binding]; other site
1151116012192	Yersinia/Haemophilus virulence surface antigen; Region: Peptidase_C58; cl04145
1151116012193	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116012194	sugar efflux transporter; Region: 2A0120; TIGR00899
1151116012195	putative substrate translocation pore; other site
1151116012196	transcriptional regulator SgrR; Provisional; Region: PRK13626
1151116012197	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1151116012198	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1151116012199	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1151116012200	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1151116012201	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1151116012202	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116012203	dimer interface [polypeptide binding]; other site
1151116012204	conserved gate region; other site
1151116012205	putative PBP binding loops; other site
1151116012206	ABC-ATPase subunit interface; other site
1151116012207	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116012208	dimer interface [polypeptide binding]; other site
1151116012209	conserved gate region; other site
1151116012210	putative PBP binding loops; other site
1151116012211	ABC-ATPase subunit interface; other site
1151116012212	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1151116012213	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1151116012214	Walker A/P-loop; other site
1151116012215	ATP binding site [chemical binding]; other site
1151116012216	Q-loop/lid; other site
1151116012217	ABC transporter signature motif; other site
1151116012218	Walker B; other site
1151116012219	D-loop; other site
1151116012220	H-loop/switch region; other site
1151116012221	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1151116012222	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1151116012223	DNA polymerase II; Reviewed; Region: PRK05762
1151116012224	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1151116012225	active site
1151116012226	catalytic site [active]
1151116012227	substrate binding site [chemical binding]; other site
1151116012228	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1151116012229	active site
1151116012230	metal-binding site
1151116012231	ATP-dependent helicase HepA; Validated; Region: PRK04914
1151116012232	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116012233	ATP binding site [chemical binding]; other site
1151116012234	putative Mg++ binding site [ion binding]; other site
1151116012235	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116012236	nucleotide binding region [chemical binding]; other site
1151116012237	ATP-binding site [chemical binding]; other site
1151116012238	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1151116012239	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1151116012240	active site
1151116012241	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
1151116012242	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1151116012243	Autotransporter beta-domain; Region: Autotransporter; smart00869
1151116012244	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1151116012245	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1151116012246	putative metal binding site [ion binding]; other site
1151116012247	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1151116012248	HSP70 interaction site [polypeptide binding]; other site
1151116012249	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1151116012250	OstA-like protein; Region: OstA; pfam03968
1151116012251	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1151116012252	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1151116012253	SurA N-terminal domain; Region: SurA_N; pfam09312
1151116012254	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1151116012255	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1151116012256	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1151116012257	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1151116012258	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1151116012259	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1151116012260	S-adenosylmethionine binding site [chemical binding]; other site
1151116012261	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1151116012262	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
1151116012263	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1151116012264	active site
1151116012265	metal binding site [ion binding]; metal-binding site
1151116012266	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1151116012267	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1151116012268	folate binding site [chemical binding]; other site
1151116012269	NADP+ binding site [chemical binding]; other site
1151116012270	hypothetical protein; Provisional; Region: PRK09917
1151116012271	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1151116012272	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1151116012273	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1151116012274	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1151116012275	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1151116012276	TrkA-N domain; Region: TrkA_N; pfam02254
1151116012277	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1151116012278	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1151116012279	N-terminal Early set domain associated with the catalytic domain of chitinase; Region: E_set_Chitinase_N; cd02848
1151116012280	Glyco_18 domain; Region: Glyco_18; smart00636
1151116012281	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1151116012282	active site
1151116012283	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1151116012284	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1151116012285	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
1151116012286	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1151116012287	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1151116012288	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1151116012289	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1151116012290	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1151116012291	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1151116012292	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1151116012293	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1151116012294	IMP binding site; other site
1151116012295	dimer interface [polypeptide binding]; other site
1151116012296	interdomain contacts; other site
1151116012297	partial ornithine binding site; other site
1151116012298	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1151116012299	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1151116012300	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1151116012301	catalytic site [active]
1151116012302	subunit interface [polypeptide binding]; other site
1151116012303	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1151116012304	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1151116012305	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1151116012306	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1151116012307	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1151116012308	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1151116012309	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1151116012310	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1151116012311	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1151116012312	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1151116012313	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1151116012314	lipoprotein signal peptidase; Provisional; Region: PRK14787
1151116012315	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1151116012316	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1151116012317	active site
1151116012318	HIGH motif; other site
1151116012319	nucleotide binding site [chemical binding]; other site
1151116012320	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1151116012321	active site
1151116012322	KMSKS motif; other site
1151116012323	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1151116012324	tRNA binding surface [nucleotide binding]; other site
1151116012325	anticodon binding site; other site
1151116012326	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1151116012327	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1151116012328	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1151116012329	active site
1151116012330	Riboflavin kinase; Region: Flavokinase; smart00904
1151116012331	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1151116012332	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1151116012333	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116012334	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1151116012335	putative dimerization interface [polypeptide binding]; other site
1151116012336	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1151116012337	chaperone protein DnaJ; Provisional; Region: PRK10767
1151116012338	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1151116012339	HSP70 interaction site [polypeptide binding]; other site
1151116012340	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1151116012341	substrate binding site [polypeptide binding]; other site
1151116012342	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1151116012343	Zn binding sites [ion binding]; other site
1151116012344	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1151116012345	dimer interface [polypeptide binding]; other site
1151116012346	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1151116012347	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1151116012348	nucleotide binding site [chemical binding]; other site
1151116012349	hypothetical protein; Provisional; Region: PRK10659
1151116012350	metabolite-proton symporter; Region: 2A0106; TIGR00883
1151116012351	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116012352	putative substrate translocation pore; other site
1151116012353	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1151116012354	MPT binding site; other site
1151116012355	trimer interface [polypeptide binding]; other site
1151116012356	transaldolase-like protein; Provisional; Region: PTZ00411
1151116012357	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1151116012358	active site
1151116012359	dimer interface [polypeptide binding]; other site
1151116012360	catalytic residue [active]
1151116012361	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1151116012362	amino acid carrier protein; Region: agcS; TIGR00835
1151116012363	hypothetical protein; Validated; Region: PRK02101
1151116012364	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1151116012365	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1151116012366	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116012367	catalytic residue [active]
1151116012368	homoserine kinase; Provisional; Region: PRK01212
1151116012369	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1151116012370	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1151116012371	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1151116012372	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1151116012373	putative catalytic residues [active]
1151116012374	putative nucleotide binding site [chemical binding]; other site
1151116012375	putative aspartate binding site [chemical binding]; other site
1151116012376	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1151116012377	dimer interface [polypeptide binding]; other site
1151116012378	putative threonine allosteric regulatory site; other site
1151116012379	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1151116012380	putative threonine allosteric regulatory site; other site
1151116012381	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1151116012382	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1151116012383	putative RNA methyltransferase; Provisional; Region: PRK10433
1151116012384	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
1151116012385	two-component response regulator; Provisional; Region: PRK11173
1151116012386	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116012387	active site
1151116012388	phosphorylation site [posttranslational modification]
1151116012389	intermolecular recognition site; other site
1151116012390	dimerization interface [polypeptide binding]; other site
1151116012391	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116012392	DNA binding site [nucleotide binding]
1151116012393	hypothetical protein; Provisional; Region: PRK10756
1151116012394	CreA protein; Region: CreA; pfam05981
1151116012395	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1151116012396	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116012397	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1151116012398	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1151116012399	catalytic core [active]
1151116012400	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1151116012401	Trp operon repressor; Provisional; Region: PRK01381
1151116012402	lytic murein transglycosylase; Provisional; Region: PRK11619
1151116012403	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116012404	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116012405	catalytic residue [active]
1151116012406	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1151116012407	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1151116012408	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1151116012409	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1151116012410	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116012411	motif II; other site
1151116012412	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1151116012413	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1151116012414	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116012415	DNA binding residues [nucleotide binding]
1151116012416	dimerization interface [polypeptide binding]; other site
1151116012417	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1151116012418	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116012419	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116012420	ABC transporter; Region: ABC_tran_2; pfam12848
1151116012421	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116012422	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116012423	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116012424	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116012425	putative effector binding pocket; other site
1151116012426	dimerization interface [polypeptide binding]; other site
1151116012427	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
1151116012428	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
1151116012429	putative NAD(P) binding site [chemical binding]; other site
1151116012430	dimer interface [polypeptide binding]; other site
1151116012431	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1151116012432	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1151116012433	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116012434	non-specific DNA binding site [nucleotide binding]; other site
1151116012435	salt bridge; other site
1151116012436	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1151116012437	sequence-specific DNA binding site [nucleotide binding]; other site
1151116012438	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1151116012439	active site
1151116012440	(T/H)XGH motif; other site
1151116012441	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1151116012442	DNA repair protein RadA; Region: sms; TIGR00416
1151116012443	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1151116012444	Walker A motif/ATP binding site; other site
1151116012445	ATP binding site [chemical binding]; other site
1151116012446	Walker B motif; other site
1151116012447	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1151116012448	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1151116012449	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116012450	motif II; other site
1151116012451	hypothetical protein; Provisional; Region: PRK11246
1151116012452	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09775
1151116012453	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116012454	putative Zn2+ binding site [ion binding]; other site
1151116012455	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1151116012456	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1151116012457	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1151116012458	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1151116012459	phosphopentomutase; Provisional; Region: PRK05362
1151116012460	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1151116012461	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1151116012462	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1151116012463	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1151116012464	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
1151116012465	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1151116012466	intersubunit interface [polypeptide binding]; other site
1151116012467	active site
1151116012468	catalytic residue [active]
1151116012469	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1151116012470	active site
1151116012471	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1151116012472	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1151116012473	active site
1151116012474	nucleophile elbow; other site
1151116012475	periplasmic protein; Provisional; Region: PRK10568
1151116012476	BON domain; Region: BON; pfam04972
1151116012477	BON domain; Region: BON; pfam04972
1151116012478	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1151116012479	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1151116012480	PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain.  Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543
1151116012481	active site
1151116012482	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1151116012483	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1151116012484	G1 box; other site
1151116012485	putative GEF interaction site [polypeptide binding]; other site
1151116012486	GTP/Mg2+ binding site [chemical binding]; other site
1151116012487	Switch I region; other site
1151116012488	G2 box; other site
1151116012489	G3 box; other site
1151116012490	Switch II region; other site
1151116012491	G4 box; other site
1151116012492	G5 box; other site
1151116012493	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1151116012494	HipA N-terminal domain; Region: Couple_hipA; pfam13657
1151116012495	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1151116012496	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1151116012497	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116012498	non-specific DNA binding site [nucleotide binding]; other site
1151116012499	salt bridge; other site
1151116012500	sequence-specific DNA binding site [nucleotide binding]; other site
1151116012501	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116012502	Coenzyme A binding pocket [chemical binding]; other site
1151116012503	DNA polymerase III subunit psi; Validated; Region: PRK06856
1151116012504	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1151116012505	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1151116012506	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116012507	S-adenosylmethionine binding site [chemical binding]; other site
1151116012508	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116012509	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116012510	active site
1151116012511	catalytic tetrad [active]
1151116012512	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116012513	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116012514	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116012515	dimerization interface [polypeptide binding]; other site
1151116012516	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1151116012517	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116012518	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116012519	metal binding site [ion binding]; metal-binding site
1151116012520	active site
1151116012521	I-site; other site
1151116012522	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
1151116012523	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1151116012524	transcriptional activator RhaR; Provisional; Region: PRK13501
1151116012525	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1151116012526	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116012527	transcriptional activator RhaS; Provisional; Region: PRK13503
1151116012528	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1151116012529	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116012530	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1151116012531	N- and C-terminal domain interface [polypeptide binding]; other site
1151116012532	active site
1151116012533	putative catalytic site [active]
1151116012534	metal binding site [ion binding]; metal-binding site
1151116012535	ATP binding site [chemical binding]; other site
1151116012536	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1151116012537	carbohydrate binding site [chemical binding]; other site
1151116012538	L-rhamnose isomerase; Provisional; Region: PRK01076
1151116012539	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
1151116012540	intersubunit interface [polypeptide binding]; other site
1151116012541	active site
1151116012542	Zn2+ binding site [ion binding]; other site
1151116012543	lactaldehyde reductase; Region: lactal_redase; TIGR02638
1151116012544	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1151116012545	dimer interface [polypeptide binding]; other site
1151116012546	active site
1151116012547	metal binding site [ion binding]; metal-binding site
1151116012548	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1151116012549	hypothetical protein; Provisional; Region: PRK01254
1151116012550	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1151116012551	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1151116012552	dihydroxyacetone kinase, ATP-dependent; Region: dak_ATP; TIGR02361
1151116012553	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
1151116012554	DAK2 domain; Region: Dak2; pfam02734
1151116012555	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1151116012556	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1151116012557	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1151116012558	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1151116012559	serine transporter; Region: stp; TIGR00814
1151116012560	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1151116012561	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1151116012562	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1151116012563	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116012564	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116012565	metal binding site [ion binding]; metal-binding site
1151116012566	active site
1151116012567	I-site; other site
1151116012568	putative outer membrane lipoprotein; Provisional; Region: PRK09967
1151116012569	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1151116012570	ligand binding site [chemical binding]; other site
1151116012571	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1151116012572	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116012573	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1151116012574	putative dimerization interface [polypeptide binding]; other site
1151116012575	putative substrate binding pocket [chemical binding]; other site
1151116012576	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
1151116012577	acetolactate synthase; Reviewed; Region: PRK08617
1151116012578	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1151116012579	PYR/PP interface [polypeptide binding]; other site
1151116012580	dimer interface [polypeptide binding]; other site
1151116012581	TPP binding site [chemical binding]; other site
1151116012582	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1151116012583	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
1151116012584	TPP-binding site [chemical binding]; other site
1151116012585	dimer interface [polypeptide binding]; other site
1151116012586	Domain of unknown function (DUF3578); Region: DUF3578; pfam12102
1151116012587	5-methylcytosine-specific restriction enzyme subunit McrB; Provisional; Region: PRK11331
1151116012588	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
1151116012589	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
1151116012590	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1151116012591	trimer interface [polypeptide binding]; other site
1151116012592	eyelet of channel; other site
1151116012593	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1151116012594	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1151116012595	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1151116012596	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1151116012597	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1151116012598	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1151116012599	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1151116012600	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1151116012601	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1151116012602	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1151116012603	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1151116012604	interface (dimer of trimers) [polypeptide binding]; other site
1151116012605	Substrate-binding/catalytic site; other site
1151116012606	Zn-binding sites [ion binding]; other site
1151116012607	DNA polymerase III subunit chi; Validated; Region: PRK05728
1151116012608	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1151116012609	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1151116012610	HIGH motif; other site
1151116012611	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1151116012612	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1151116012613	active site
1151116012614	KMSKS motif; other site
1151116012615	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1151116012616	tRNA binding surface [nucleotide binding]; other site
1151116012617	anticodon binding site; other site
1151116012618	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1151116012619	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1151116012620	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116012621	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116012622	dimerization interface [polypeptide binding]; other site
1151116012623	Fimbrial protein; Region: Fimbrial; pfam00419
1151116012624	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1151116012625	PapC N-terminal domain; Region: PapC_N; pfam13954
1151116012626	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1151116012627	PapC C-terminal domain; Region: PapC_C; pfam13953
1151116012628	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1151116012629	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1151116012630	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1151116012631	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1151116012632	Fimbrial protein; Region: Fimbrial; pfam00419
1151116012633	Peptidase family M48; Region: Peptidase_M48; cl12018
1151116012634	Bacterial protein of unknown function (DUF898); Region: DUF898; pfam05987
1151116012635	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1151116012636	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116012637	Coenzyme A binding pocket [chemical binding]; other site
1151116012638	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1151116012639	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116012640	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1151116012641	putative active site [active]
1151116012642	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1151116012643	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116012644	active site turn [active]
1151116012645	phosphorylation site [posttranslational modification]
1151116012646	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116012647	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1151116012648	beta-galactosidase; Region: BGL; TIGR03356
1151116012649	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
1151116012650	RNase E inhibitor protein; Provisional; Region: PRK11191
1151116012651	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1151116012652	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1151116012653	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1151116012654	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
1151116012655	active site
1151116012656	homodimer interface [polypeptide binding]; other site
1151116012657	catalytic site [active]
1151116012658	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1151116012659	arginine deiminase; Provisional; Region: PRK01388
1151116012660	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1151116012661	putative substrate binding site [chemical binding]; other site
1151116012662	homodimer interface [polypeptide binding]; other site
1151116012663	nucleotide binding site [chemical binding]; other site
1151116012664	nucleotide binding site [chemical binding]; other site
1151116012665	ornithine carbamoyltransferase; Validated; Region: PRK02102
1151116012666	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1151116012667	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1151116012668	Predicted membrane protein [Function unknown]; Region: COG1288
1151116012669	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1151116012670	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1151116012671	arginine repressor; Provisional; Region: argR; PRK00441
1151116012672	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1151116012673	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1151116012674	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1151116012675	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1151116012676	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1151116012677	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1151116012678	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1151116012679	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1151116012680	homotrimer interaction site [polypeptide binding]; other site
1151116012681	putative active site [active]
1151116012682	Peptidase family M23; Region: Peptidase_M23; pfam01551
1151116012683	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1151116012684	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1151116012685	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1151116012686	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1151116012687	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
1151116012688	Uncharacterized conserved protein [Function unknown]; Region: COG2308
1151116012689	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
1151116012690	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
1151116012691	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1151116012692	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
1151116012693	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1151116012694	Predicted proteasome-type protease [Posttranslational modification, protein turnover, chaperones]; Region: COG3484
1151116012695	Bacterial proteasome, beta subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that...; Region: proteasome_beta_bacterial; cd03765
1151116012696	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116012697	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116012698	DNA binding site [nucleotide binding]
1151116012699	domain linker motif; other site
1151116012700	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
1151116012701	putative dimerization interface [polypeptide binding]; other site
1151116012702	putative ligand binding site [chemical binding]; other site
1151116012703	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
1151116012704	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1151116012705	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1151116012706	Walker A/P-loop; other site
1151116012707	ATP binding site [chemical binding]; other site
1151116012708	Q-loop/lid; other site
1151116012709	ABC transporter signature motif; other site
1151116012710	Walker B; other site
1151116012711	D-loop; other site
1151116012712	H-loop/switch region; other site
1151116012713	TOBE domain; Region: TOBE_2; pfam08402
1151116012714	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1151116012715	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116012716	motif II; other site
1151116012717	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
1151116012718	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1151116012719	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1151116012720	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1151116012721	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1151116012722	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1151116012723	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1151116012724	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1151116012725	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1151116012726	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
1151116012727	putative NAD(P) binding site [chemical binding]; other site
1151116012728	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116012729	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116012730	dimer interface [polypeptide binding]; other site
1151116012731	conserved gate region; other site
1151116012732	putative PBP binding loops; other site
1151116012733	ABC-ATPase subunit interface; other site
1151116012734	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1151116012735	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116012736	dimer interface [polypeptide binding]; other site
1151116012737	conserved gate region; other site
1151116012738	putative PBP binding loops; other site
1151116012739	ABC-ATPase subunit interface; other site
1151116012740	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1151116012741	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1151116012742	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
1151116012743	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
1151116012744	active site
1151116012745	homodimer interface [polypeptide binding]; other site
1151116012746	catalytic site [active]
1151116012747	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
1151116012748	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1151116012749	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1151116012750	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1151116012751	altronate oxidoreductase; Provisional; Region: PRK03643
1151116012752	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1151116012753	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1151116012754	Glucuronate isomerase; Region: UxaC; pfam02614
1151116012755	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1151116012756	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116012757	D-galactonate transporter; Region: 2A0114; TIGR00893
1151116012758	putative substrate translocation pore; other site
1151116012759	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
1151116012760	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116012761	DNA-binding site [nucleotide binding]; DNA binding site
1151116012762	FCD domain; Region: FCD; pfam07729
1151116012763	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1151116012764	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1151116012765	SecD export protein N-terminal TM region; Region: SecD-TM1; cl08136
1151116012766	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1151116012767	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1151116012768	Predicted membrane protein [Function unknown]; Region: COG5393
1151116012769	YqjK-like protein; Region: YqjK; pfam13997
1151116012770	Predicted membrane protein [Function unknown]; Region: COG2259
1151116012771	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1151116012772	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1151116012773	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1151116012774	putative dimer interface [polypeptide binding]; other site
1151116012775	N-terminal domain interface [polypeptide binding]; other site
1151116012776	putative substrate binding pocket (H-site) [chemical binding]; other site
1151116012777	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116012778	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1151116012779	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116012780	dimerization interface [polypeptide binding]; other site
1151116012781	Pirin-related protein [General function prediction only]; Region: COG1741
1151116012782	Pirin; Region: Pirin; pfam02678
1151116012783	Toxin-coregulated pilus subunit TcpA; Region: TcpA; pfam05946
1151116012784	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
1151116012785	type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520
1151116012786	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1151116012787	Type II/IV secretion system protein; Region: T2SE; pfam00437
1151116012788	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1151116012789	Walker A motif; other site
1151116012790	ATP binding site [chemical binding]; other site
1151116012791	Walker B motif; other site
1151116012792	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1151116012793	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1151116012794	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1151116012795	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1151116012796	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1151116012797	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1151116012798	Peptidase family M23; Region: Peptidase_M23; pfam01551
1151116012799	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1151116012800	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1151116012801	putative SAM binding site [chemical binding]; other site
1151116012802	putative homodimer interface [polypeptide binding]; other site
1151116012803	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1151116012804	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1151116012805	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1151116012806	putative ligand binding site [chemical binding]; other site
1151116012807	hypothetical protein; Reviewed; Region: PRK12497
1151116012808	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1151116012809	dimer interface [polypeptide binding]; other site
1151116012810	active site
1151116012811	outer membrane lipoprotein; Provisional; Region: PRK11023
1151116012812	BON domain; Region: BON; pfam04972
1151116012813	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116012814	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116012815	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116012816	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1151116012817	Transglycosylase; Region: Transgly; cl17702
1151116012818	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1151116012819	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116012820	putative active site [active]
1151116012821	heme pocket [chemical binding]; other site
1151116012822	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116012823	dimer interface [polypeptide binding]; other site
1151116012824	phosphorylation site [posttranslational modification]
1151116012825	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116012826	ATP binding site [chemical binding]; other site
1151116012827	Mg2+ binding site [ion binding]; other site
1151116012828	G-X-G motif; other site
1151116012829	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116012830	active site
1151116012831	phosphorylation site [posttranslational modification]
1151116012832	intermolecular recognition site; other site
1151116012833	dimerization interface [polypeptide binding]; other site
1151116012834	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1151116012835	putative binding surface; other site
1151116012836	active site
1151116012837	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1151116012838	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1151116012839	active site
1151116012840	dimer interface [polypeptide binding]; other site
1151116012841	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1151116012842	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1151116012843	active site
1151116012844	FMN binding site [chemical binding]; other site
1151116012845	substrate binding site [chemical binding]; other site
1151116012846	3Fe-4S cluster binding site [ion binding]; other site
1151116012847	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1151116012848	domain interface; other site
1151116012849	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1151116012850	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1151116012851	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1151116012852	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1151116012853	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
1151116012854	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1151116012855	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1151116012856	C-terminal domain interface [polypeptide binding]; other site
1151116012857	putative GSH binding site (G-site) [chemical binding]; other site
1151116012858	dimer interface [polypeptide binding]; other site
1151116012859	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1151116012860	dimer interface [polypeptide binding]; other site
1151116012861	N-terminal domain interface [polypeptide binding]; other site
1151116012862	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1151116012863	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1151116012864	23S rRNA interface [nucleotide binding]; other site
1151116012865	L3 interface [polypeptide binding]; other site
1151116012866	Predicted ATPase [General function prediction only]; Region: COG1485
1151116012867	hypothetical protein; Provisional; Region: PRK11677
1151116012868	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1151116012869	serine endoprotease; Provisional; Region: PRK10139
1151116012870	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1151116012871	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1151116012872	protein binding site [polypeptide binding]; other site
1151116012873	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1151116012874	protein binding site [polypeptide binding]; other site
1151116012875	serine endoprotease; Provisional; Region: PRK10898
1151116012876	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1151116012877	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1151116012878	protein binding site [polypeptide binding]; other site
1151116012879	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1151116012880	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1151116012881	hinge; other site
1151116012882	active site
1151116012883	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1151116012884	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1151116012885	anti sigma factor interaction site; other site
1151116012886	regulatory phosphorylation site [posttranslational modification]; other site
1151116012887	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1151116012888	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1151116012889	mce related protein; Region: MCE; pfam02470
1151116012890	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1151116012891	conserved hypothetical integral membrane protein; Region: TIGR00056
1151116012892	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1151116012893	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1151116012894	Walker A/P-loop; other site
1151116012895	ATP binding site [chemical binding]; other site
1151116012896	Q-loop/lid; other site
1151116012897	ABC transporter signature motif; other site
1151116012898	Walker B; other site
1151116012899	D-loop; other site
1151116012900	H-loop/switch region; other site
1151116012901	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1151116012902	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1151116012903	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1151116012904	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1151116012905	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1151116012906	putative active site [active]
1151116012907	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1151116012908	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1151116012909	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1151116012910	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1151116012911	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1151116012912	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1151116012913	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1151116012914	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1151116012915	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1151116012916	Walker A/P-loop; other site
1151116012917	ATP binding site [chemical binding]; other site
1151116012918	Q-loop/lid; other site
1151116012919	ABC transporter signature motif; other site
1151116012920	Walker B; other site
1151116012921	D-loop; other site
1151116012922	H-loop/switch region; other site
1151116012923	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1151116012924	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1151116012925	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1151116012926	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1151116012927	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1151116012928	30S subunit binding site; other site
1151116012929	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1151116012930	active site
1151116012931	phosphorylation site [posttranslational modification]
1151116012932	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
1151116012933	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1151116012934	dimerization domain swap beta strand [polypeptide binding]; other site
1151116012935	regulatory protein interface [polypeptide binding]; other site
1151116012936	active site
1151116012937	regulatory phosphorylation site [posttranslational modification]; other site
1151116012938	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1151116012939	HTH domain; Region: HTH_11; pfam08279
1151116012940	Mga helix-turn-helix domain; Region: Mga; pfam05043
1151116012941	PRD domain; Region: PRD; pfam00874
1151116012942	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1151116012943	active site
1151116012944	P-loop; other site
1151116012945	phosphorylation site [posttranslational modification]
1151116012946	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1151116012947	active site
1151116012948	phosphorylation site [posttranslational modification]
1151116012949	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1151116012950	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1151116012951	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116012952	catalytic residue [active]
1151116012953	dihydroorotase; Provisional; Region: PRK09237
1151116012954	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1151116012955	active site
1151116012956	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
1151116012957	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1151116012958	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
1151116012959	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; cl11916
1151116012960	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1151116012961	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1151116012962	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1151116012963	Cytochrome b562; Region: Cytochrom_B562; cl01546
1151116012964	peptidase PmbA; Provisional; Region: PRK11040
1151116012965	hypothetical protein; Provisional; Region: PRK05255
1151116012966	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1151116012967	RNAase interaction site [polypeptide binding]; other site
1151116012968	microbial_RNases. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential  for both non-specific RNA degradation and for numerous forms of RNA processing. The alignment contains fungal RNases (U2, T1, F1, Th,  Pb, N1, and Ms) and...; Region: microbial_RNases; cl00212
1151116012969	active site
1151116012970	succinic semialdehyde dehydrogenase; Region: PLN02278
1151116012971	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1151116012972	tetramerization interface [polypeptide binding]; other site
1151116012973	NAD(P) binding site [chemical binding]; other site
1151116012974	catalytic residues [active]
1151116012975	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
1151116012976	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1151116012977	active site
1151116012978	substrate binding site [chemical binding]; other site
1151116012979	trimer interface [polypeptide binding]; other site
1151116012980	CoA binding site [chemical binding]; other site
1151116012981	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1151116012982	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1151116012983	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
1151116012984	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1151116012985	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116012986	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116012987	efflux system membrane protein; Provisional; Region: PRK11594
1151116012988	transcriptional regulator; Provisional; Region: PRK10632
1151116012989	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116012990	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116012991	putative effector binding pocket; other site
1151116012992	dimerization interface [polypeptide binding]; other site
1151116012993	protease TldD; Provisional; Region: tldD; PRK10735
1151116012994	hypothetical protein; Provisional; Region: PRK10899
1151116012995	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1151116012996	ribonuclease G; Provisional; Region: PRK11712
1151116012997	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1151116012998	homodimer interface [polypeptide binding]; other site
1151116012999	oligonucleotide binding site [chemical binding]; other site
1151116013000	Maf-like protein; Region: Maf; pfam02545
1151116013001	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1151116013002	active site
1151116013003	dimer interface [polypeptide binding]; other site
1151116013004	rod shape-determining protein MreD; Provisional; Region: PRK11060
1151116013005	rod shape-determining protein MreC; Region: mreC; TIGR00219
1151116013006	rod shape-determining protein MreC; Region: MreC; pfam04085
1151116013007	rod shape-determining protein MreB; Provisional; Region: PRK13927
1151116013008	MreB and similar proteins; Region: MreB_like; cd10225
1151116013009	nucleotide binding site [chemical binding]; other site
1151116013010	Mg binding site [ion binding]; other site
1151116013011	putative protofilament interaction site [polypeptide binding]; other site
1151116013012	RodZ interaction site [polypeptide binding]; other site
1151116013013	regulatory protein CsrD; Provisional; Region: PRK11059
1151116013014	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116013015	metal binding site [ion binding]; metal-binding site
1151116013016	active site
1151116013017	I-site; other site
1151116013018	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116013019	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1151116013020	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1151116013021	Moco binding site; other site
1151116013022	metal coordination site [ion binding]; other site
1151116013023	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1151116013024	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1151116013025	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1151116013026	active site
1151116013027	trimer interface [polypeptide binding]; other site
1151116013028	dimer interface [polypeptide binding]; other site
1151116013029	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1151116013030	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1151116013031	carboxyltransferase (CT) interaction site; other site
1151116013032	biotinylation site [posttranslational modification]; other site
1151116013033	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1151116013034	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1151116013035	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1151116013036	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1151116013037	hypothetical protein; Provisional; Region: PRK10633
1151116013038	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1151116013039	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1151116013040	Na binding site [ion binding]; other site
1151116013041	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1151116013042	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116013043	S-adenosylmethionine binding site [chemical binding]; other site
1151116013044	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
1151116013045	active site
1151116013046	zinc binding site [ion binding]; other site
1151116013047	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1151116013048	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1151116013049	FMN binding site [chemical binding]; other site
1151116013050	active site
1151116013051	catalytic residues [active]
1151116013052	substrate binding site [chemical binding]; other site
1151116013053	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1151116013054	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1151116013055	Predicted membrane protein [Function unknown]; Region: COG2259
1151116013056	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1151116013057	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1151116013058	putative acyl-acceptor binding pocket; other site
1151116013059	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1151116013060	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116013061	substrate binding pocket [chemical binding]; other site
1151116013062	membrane-bound complex binding site; other site
1151116013063	hinge residues; other site
1151116013064	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
1151116013065	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116013066	conserved gate region; other site
1151116013067	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116013068	dimer interface [polypeptide binding]; other site
1151116013069	conserved gate region; other site
1151116013070	putative PBP binding loops; other site
1151116013071	ABC-ATPase subunit interface; other site
1151116013072	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116013073	dimer interface [polypeptide binding]; other site
1151116013074	conserved gate region; other site
1151116013075	putative PBP binding loops; other site
1151116013076	ABC-ATPase subunit interface; other site
1151116013077	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1151116013078	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1151116013079	Walker A/P-loop; other site
1151116013080	ATP binding site [chemical binding]; other site
1151116013081	Q-loop/lid; other site
1151116013082	ABC transporter signature motif; other site
1151116013083	Walker B; other site
1151116013084	D-loop; other site
1151116013085	H-loop/switch region; other site
1151116013086	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1151116013087	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1151116013088	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116013089	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116013090	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116013091	dimerization interface [polypeptide binding]; other site
1151116013092	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1151116013093	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1151116013094	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1151116013095	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1151116013096	putative C-terminal domain interface [polypeptide binding]; other site
1151116013097	putative GSH binding site (G-site) [chemical binding]; other site
1151116013098	putative dimer interface [polypeptide binding]; other site
1151116013099	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1151116013100	putative N-terminal domain interface [polypeptide binding]; other site
1151116013101	putative dimer interface [polypeptide binding]; other site
1151116013102	putative substrate binding pocket (H-site) [chemical binding]; other site
1151116013103	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1151116013104	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1151116013105	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116013106	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116013107	metal binding site [ion binding]; metal-binding site
1151116013108	active site
1151116013109	I-site; other site
1151116013110	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116013111	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1151116013112	HAMP domain; Region: HAMP; pfam00672
1151116013113	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1151116013114	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116013115	dimer interface [polypeptide binding]; other site
1151116013116	putative CheW interface [polypeptide binding]; other site
1151116013117	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1151116013118	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
1151116013119	active site
1151116013120	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1151116013121	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1151116013122	putative ligand binding residues [chemical binding]; other site
1151116013123	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1151116013124	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1151116013125	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
1151116013126	Serine/threonine protein kinase involved in cell cycle control [Signal transduction mechanisms / Cell division and chromosome partitioning]; Region: RIO1; COG1718
1151116013127	RIO kinase family; RIO1, RIO3 and similar proteins, catalytic domain. The RIO kinase catalytic domain family is part of a larger superfamily, that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; Region: RIO1_like; cd05145
1151116013128	ATP binding site [chemical binding]; other site
1151116013129	Male sterility protein; Region: NAD_binding_4; pfam07993
1151116013130	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1151116013131	NAD(P) binding site [chemical binding]; other site
1151116013132	active site
1151116013133	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1151116013134	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1151116013135	putative C-terminal domain interface [polypeptide binding]; other site
1151116013136	putative GSH binding site (G-site) [chemical binding]; other site
1151116013137	putative dimer interface [polypeptide binding]; other site
1151116013138	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1151116013139	putative N-terminal domain interface [polypeptide binding]; other site
1151116013140	putative dimer interface [polypeptide binding]; other site
1151116013141	putative substrate binding pocket (H-site) [chemical binding]; other site
1151116013142	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1151116013143	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1151116013144	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1151116013145	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116013146	EamA-like transporter family; Region: EamA; pfam00892
1151116013147	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1151116013148	active site 1 [active]
1151116013149	dimer interface [polypeptide binding]; other site
1151116013150	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1151116013151	hexamer interface [polypeptide binding]; other site
1151116013152	active site 2 [active]
1151116013153	PemK-like protein; Region: PemK; cl00995
1151116013154	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1151116013155	short chain dehydrogenase; Provisional; Region: PRK12937
1151116013156	tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs; Region: THN_reductase-like_SDR_c; cd05362
1151116013157	NADP binding site [chemical binding]; other site
1151116013158	homodimer interface [polypeptide binding]; other site
1151116013159	active site
1151116013160	substrate binding site [chemical binding]; other site
1151116013161	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116013162	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116013163	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1151116013164	putative effector binding pocket; other site
1151116013165	putative dimerization interface [polypeptide binding]; other site
1151116013166	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
1151116013167	salicylate hydroxylase; Provisional; Region: PRK08163
1151116013168	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1151116013169	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1151116013170	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1151116013171	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116013172	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116013173	dimerization interface [polypeptide binding]; other site
1151116013174	putative deaminase; Validated; Region: PRK06846
1151116013175	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1151116013176	active site
1151116013177	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1151116013178	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1151116013179	dimer interface [polypeptide binding]; other site
1151116013180	ssDNA binding site [nucleotide binding]; other site
1151116013181	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1151116013182	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1151116013183	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1151116013184	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116013185	ABC transporter signature motif; other site
1151116013186	Walker B; other site
1151116013187	D-loop; other site
1151116013188	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1151116013189	Helix-turn-helix domain; Region: HTH_36; pfam13730
1151116013190	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
1151116013191	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1151116013192	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1151116013193	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116013194	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116013195	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_2; cd08471
1151116013196	putative effector binding pocket; other site
1151116013197	putative dimerization interface [polypeptide binding]; other site
1151116013198	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1151116013199	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1151116013200	C-terminal, alpha helical domain of an unknown subfamily 7 of Glutathione S-transferases; Region: GST_C_7; cd03206
1151116013201	putative N-terminal domain interface [polypeptide binding]; other site
1151116013202	putative dimer interface [polypeptide binding]; other site
1151116013203	putative substrate binding pocket (H-site) [chemical binding]; other site
1151116013204	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1151116013205	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1151116013206	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1151116013207	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1151116013208	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1151116013209	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1151116013210	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1151116013211	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116013212	alpha-glucosidase; Provisional; Region: PRK10426
1151116013213	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1151116013214	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
1151116013215	putative active site [active]
1151116013216	putative catalytic site [active]
1151116013217	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
1151116013218	dimerization interface [polypeptide binding]; other site
1151116013219	putative active cleft [active]
1151116013220	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
1151116013221	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1151116013222	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1151116013223	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116013224	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1151116013225	substrate binding site [chemical binding]; other site
1151116013226	ATP binding site [chemical binding]; other site
1151116013227	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1151116013228	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116013229	putative DNA binding site [nucleotide binding]; other site
1151116013230	putative Zn2+ binding site [ion binding]; other site
1151116013231	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1151116013232	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1151116013233	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116013234	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116013235	homodimer interface [polypeptide binding]; other site
1151116013236	catalytic residue [active]
1151116013237	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116013238	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1151116013239	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1151116013240	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1151116013241	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1151116013242	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
1151116013243	AsnC family; Region: AsnC_trans_reg; pfam01037
1151116013244	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116013245	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1151116013246	substrate binding pocket [chemical binding]; other site
1151116013247	membrane-bound complex binding site; other site
1151116013248	hinge residues; other site
1151116013249	alanine racemase; Reviewed; Region: alr; PRK00053
1151116013250	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1151116013251	active site
1151116013252	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1151116013253	substrate binding site [chemical binding]; other site
1151116013254	catalytic residues [active]
1151116013255	dimer interface [polypeptide binding]; other site
1151116013256	replicative DNA helicase; Provisional; Region: PRK08006
1151116013257	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1151116013258	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1151116013259	Walker A motif; other site
1151116013260	ATP binding site [chemical binding]; other site
1151116013261	Walker B motif; other site
1151116013262	DNA binding loops [nucleotide binding]
1151116013263	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1151116013264	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1151116013265	NADP binding site [chemical binding]; other site
1151116013266	dimer interface [polypeptide binding]; other site
1151116013267	Phage shock protein G (Phageshock_PspG); Region: Phageshock_PspG; cl11511
1151116013268	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1151116013269	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1151116013270	FMN binding site [chemical binding]; other site
1151116013271	active site
1151116013272	catalytic residues [active]
1151116013273	substrate binding site [chemical binding]; other site
1151116013274	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1151116013275	metal binding site 2 [ion binding]; metal-binding site
1151116013276	putative DNA binding helix; other site
1151116013277	metal binding site 1 [ion binding]; metal-binding site
1151116013278	structural Zn2+ binding site [ion binding]; other site
1151116013279	hypothetical protein; Provisional; Region: PRK10428
1151116013280	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1151116013281	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1151116013282	LexA repressor; Validated; Region: PRK00215
1151116013283	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1151116013284	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1151116013285	Catalytic site [active]
1151116013286	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1151116013287	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1151116013288	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1151116013289	putative acyl-acceptor binding pocket; other site
1151116013290	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1151116013291	UbiA prenyltransferase family; Region: UbiA; pfam01040
1151116013292	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1151116013293	Chorismate lyase; Region: Chor_lyase; cl01230
1151116013294	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
1151116013295	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1151116013296	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1151116013297	active site
1151116013298	dimer interface [polypeptide binding]; other site
1151116013299	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1151116013300	dimer interface [polypeptide binding]; other site
1151116013301	active site
1151116013302	aspartate kinase III; Validated; Region: PRK09084
1151116013303	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1151116013304	nucleotide binding site [chemical binding]; other site
1151116013305	substrate binding site [chemical binding]; other site
1151116013306	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1151116013307	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1151116013308	dimer interface [polypeptide binding]; other site
1151116013309	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1151116013310	Sodium Bile acid symporter family; Region: SBF; pfam01758
1151116013311	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1151116013312	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1151116013313	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1151116013314	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1151116013315	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1151116013316	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1151116013317	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116013318	Walker A/P-loop; other site
1151116013319	ATP binding site [chemical binding]; other site
1151116013320	Q-loop/lid; other site
1151116013321	ABC transporter signature motif; other site
1151116013322	Walker B; other site
1151116013323	D-loop; other site
1151116013324	H-loop/switch region; other site
1151116013325	TOBE domain; Region: TOBE_2; pfam08402
1151116013326	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1151116013327	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116013328	dimer interface [polypeptide binding]; other site
1151116013329	conserved gate region; other site
1151116013330	putative PBP binding loops; other site
1151116013331	ABC-ATPase subunit interface; other site
1151116013332	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1151116013333	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116013334	putative PBP binding loops; other site
1151116013335	ABC-ATPase subunit interface; other site
1151116013336	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
1151116013337	Sulfatase; Region: Sulfatase; cl17466
1151116013338	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1151116013339	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1151116013340	transcriptional regulator protein; Region: phnR; TIGR03337
1151116013341	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116013342	DNA-binding site [nucleotide binding]; DNA binding site
1151116013343	UTRA domain; Region: UTRA; pfam07702
1151116013344	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1151116013345	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1151116013346	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1151116013347	substrate binding pocket [chemical binding]; other site
1151116013348	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1151116013349	B12 binding site [chemical binding]; other site
1151116013350	cobalt ligand [ion binding]; other site
1151116013351	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1151116013352	transcriptional repressor IclR; Provisional; Region: PRK11569
1151116013353	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1151116013354	Bacterial transcriptional regulator; Region: IclR; pfam01614
1151116013355	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1151116013356	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1151116013357	isocitrate lyase; Provisional; Region: PRK15063
1151116013358	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1151116013359	tetramer interface [polypeptide binding]; other site
1151116013360	active site
1151116013361	Mg2+/Mn2+ binding site [ion binding]; other site
1151116013362	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1151116013363	malate synthase A; Region: malate_syn_A; TIGR01344
1151116013364	active site
1151116013365	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1151116013366	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1151116013367	proposed active site lysine [active]
1151116013368	conserved cys residue [active]
1151116013369	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1151116013370	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1151116013371	purine monophosphate binding site [chemical binding]; other site
1151116013372	dimer interface [polypeptide binding]; other site
1151116013373	putative catalytic residues [active]
1151116013374	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1151116013375	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1151116013376	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1151116013377	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1151116013378	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1151116013379	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1151116013380	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1151116013381	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1151116013382	IHF dimer interface [polypeptide binding]; other site
1151116013383	IHF - DNA interface [nucleotide binding]; other site
1151116013384	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1151116013385	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1151116013386	Active_site [active]
1151116013387	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1151116013388	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1151116013389	substrate binding site [chemical binding]; other site
1151116013390	active site
1151116013391	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1151116013392	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1151116013393	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1151116013394	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1151116013395	putative NADH binding site [chemical binding]; other site
1151116013396	putative active site [active]
1151116013397	nudix motif; other site
1151116013398	putative metal binding site [ion binding]; other site
1151116013399	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1151116013400	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1151116013401	ThiC-associated domain; Region: ThiC-associated; pfam13667
1151116013402	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1151116013403	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1151116013404	thiamine phosphate binding site [chemical binding]; other site
1151116013405	active site
1151116013406	pyrophosphate binding site [ion binding]; other site
1151116013407	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1151116013408	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1151116013409	ATP binding site [chemical binding]; other site
1151116013410	substrate interface [chemical binding]; other site
1151116013411	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1151116013412	thiS-thiF/thiG interaction site; other site
1151116013413	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1151116013414	ThiS interaction site; other site
1151116013415	putative active site [active]
1151116013416	tetramer interface [polypeptide binding]; other site
1151116013417	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1151116013418	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116013419	FeS/SAM binding site; other site
1151116013420	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1151116013421	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1151116013422	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1151116013423	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1151116013424	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1151116013425	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1151116013426	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1151116013427	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1151116013428	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1151116013429	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1151116013430	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1151116013431	DNA binding site [nucleotide binding]
1151116013432	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1151116013433	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1151116013434	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1151116013435	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1151116013436	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1151116013437	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1151116013438	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1151116013439	RPB3 interaction site [polypeptide binding]; other site
1151116013440	RPB1 interaction site [polypeptide binding]; other site
1151116013441	RPB11 interaction site [polypeptide binding]; other site
1151116013442	RPB10 interaction site [polypeptide binding]; other site
1151116013443	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1151116013444	core dimer interface [polypeptide binding]; other site
1151116013445	peripheral dimer interface [polypeptide binding]; other site
1151116013446	L10 interface [polypeptide binding]; other site
1151116013447	L11 interface [polypeptide binding]; other site
1151116013448	putative EF-Tu interaction site [polypeptide binding]; other site
1151116013449	putative EF-G interaction site [polypeptide binding]; other site
1151116013450	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1151116013451	23S rRNA interface [nucleotide binding]; other site
1151116013452	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1151116013453	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1151116013454	mRNA/rRNA interface [nucleotide binding]; other site
1151116013455	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1151116013456	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1151116013457	23S rRNA interface [nucleotide binding]; other site
1151116013458	L7/L12 interface [polypeptide binding]; other site
1151116013459	putative thiostrepton binding site; other site
1151116013460	L25 interface [polypeptide binding]; other site
1151116013461	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1151116013462	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1151116013463	putative homodimer interface [polypeptide binding]; other site
1151116013464	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1151116013465	heterodimer interface [polypeptide binding]; other site
1151116013466	homodimer interface [polypeptide binding]; other site
1151116013467	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1151116013468	elongation factor Tu; Reviewed; Region: PRK00049
1151116013469	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1151116013470	G1 box; other site
1151116013471	GEF interaction site [polypeptide binding]; other site
1151116013472	GTP/Mg2+ binding site [chemical binding]; other site
1151116013473	Switch I region; other site
1151116013474	G2 box; other site
1151116013475	G3 box; other site
1151116013476	Switch II region; other site
1151116013477	G4 box; other site
1151116013478	G5 box; other site
1151116013479	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1151116013480	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1151116013481	Antibiotic Binding Site [chemical binding]; other site
1151116013482	pantothenate kinase; Provisional; Region: PRK05439
1151116013483	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1151116013484	ATP-binding site [chemical binding]; other site
1151116013485	CoA-binding site [chemical binding]; other site
1151116013486	Mg2+-binding site [ion binding]; other site
1151116013487	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1151116013488	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1151116013489	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1151116013490	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1151116013491	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1151116013492	FAD binding domain; Region: FAD_binding_4; pfam01565
1151116013493	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1151116013494	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1151116013495	potassium transporter; Provisional; Region: PRK10750
1151116013496	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1151116013497	hypothetical protein; Provisional; Region: PRK11568
1151116013498	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1151116013499	proline dipeptidase; Provisional; Region: PRK13607
1151116013500	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1151116013501	active site
1151116013502	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1151116013503	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1151116013504	substrate binding site [chemical binding]; other site
1151116013505	oxyanion hole (OAH) forming residues; other site
1151116013506	trimer interface [polypeptide binding]; other site
1151116013507	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1151116013508	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1151116013509	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1151116013510	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1151116013511	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1151116013512	dimer interface [polypeptide binding]; other site
1151116013513	active site
1151116013514	potential frameshift: common BLAST hit: gi|322834839|ref|YP_004214866.1| oxidoreductase FAD/NAD(P)-binding domain-containing protein
1151116013515	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1151116013516	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1151116013517	active site pocket [active]
1151116013518	oxyanion hole [active]
1151116013519	catalytic triad [active]
1151116013520	active site nucleophile [active]
1151116013521	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1151116013522	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1151116013523	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1151116013524	active site
1151116013525	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1151116013526	sec-independent translocase; Provisional; Region: PRK01770
1151116013527	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
1151116013528	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1151116013529	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1151116013530	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1151116013531	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1151116013532	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1151116013533	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116013534	S-adenosylmethionine binding site [chemical binding]; other site
1151116013535	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1151116013536	DNA recombination protein RmuC; Provisional; Region: PRK10361
1151116013537	RmuC family; Region: RmuC; pfam02646
1151116013538	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1151116013539	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1151116013540	uridine phosphorylase; Provisional; Region: PRK11178
1151116013541	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1151116013542	hydroperoxidase II; Provisional; Region: katE; PRK11249
1151116013543	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1151116013544	tetramer interface [polypeptide binding]; other site
1151116013545	heme binding pocket [chemical binding]; other site
1151116013546	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1151116013547	domain interactions; other site
1151116013548	Dienelactone hydrolase family; Region: DLH; pfam01738
1151116013549	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1151116013550	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1151116013551	active site
1151116013552	intersubunit interactions; other site
1151116013553	catalytic residue [active]
1151116013554	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1151116013555	dimerization domain swap beta strand [polypeptide binding]; other site
1151116013556	regulatory protein interface [polypeptide binding]; other site
1151116013557	active site
1151116013558	regulatory phosphorylation site [posttranslational modification]; other site
1151116013559	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1151116013560	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1151116013561	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1151116013562	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1151116013563	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1151116013564	active site
1151116013565	phosphorylation site [posttranslational modification]
1151116013566	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1151116013567	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1151116013568	active site
1151116013569	P-loop; other site
1151116013570	phosphorylation site [posttranslational modification]
1151116013571	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1151116013572	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1151116013573	dimer interface [polypeptide binding]; other site
1151116013574	active site
1151116013575	glycine loop; other site
1151116013576	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116013577	FeS/SAM binding site; other site
1151116013578	pyruvate formate lyase II activase; Provisional; Region: PRK10076
1151116013579	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1151116013580	active site
1151116013581	P-loop; other site
1151116013582	phosphorylation site [posttranslational modification]
1151116013583	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1151116013584	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116013585	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1151116013586	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1151116013587	THF binding site; other site
1151116013588	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1151116013589	substrate binding site [chemical binding]; other site
1151116013590	THF binding site; other site
1151116013591	zinc-binding site [ion binding]; other site
1151116013592	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1151116013593	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116013594	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1151116013595	putative dimerization interface [polypeptide binding]; other site
1151116013596	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1151116013597	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1151116013598	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1151116013599	putative active site [active]
1151116013600	catalytic site [active]
1151116013601	putative metal binding site [ion binding]; other site
1151116013602	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1151116013603	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1151116013604	Walker A/P-loop; other site
1151116013605	ATP binding site [chemical binding]; other site
1151116013606	Q-loop/lid; other site
1151116013607	ABC transporter signature motif; other site
1151116013608	Walker B; other site
1151116013609	D-loop; other site
1151116013610	H-loop/switch region; other site
1151116013611	TOBE domain; Region: TOBE_2; pfam08402
1151116013612	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116013613	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116013614	dimer interface [polypeptide binding]; other site
1151116013615	conserved gate region; other site
1151116013616	putative PBP binding loops; other site
1151116013617	ABC-ATPase subunit interface; other site
1151116013618	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1151116013619	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116013620	dimer interface [polypeptide binding]; other site
1151116013621	conserved gate region; other site
1151116013622	putative PBP binding loops; other site
1151116013623	ABC-ATPase subunit interface; other site
1151116013624	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1151116013625	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1151116013626	Protein of unknown function (DUF796); Region: DUF796; cl01226
1151116013627	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1151116013628	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116013629	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116013630	homodimer interface [polypeptide binding]; other site
1151116013631	catalytic residue [active]
1151116013632	potential frameshift: common BLAST hit: gi|322834877|ref|YP_004214904.1| ABC transporter
1151116013633	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1151116013634	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1151116013635	Walker A/P-loop; other site
1151116013636	ATP binding site [chemical binding]; other site
1151116013637	Q-loop/lid; other site
1151116013638	ABC transporter signature motif; other site
1151116013639	Walker B; other site
1151116013640	D-loop; other site
1151116013641	H-loop/switch region; other site
1151116013642	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1151116013643	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1151116013644	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1151116013645	TM-ABC transporter signature motif; other site
1151116013646	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116013647	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1151116013648	TM-ABC transporter signature motif; other site
1151116013649	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1151116013650	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1151116013651	dimerization interface [polypeptide binding]; other site
1151116013652	ligand binding site [chemical binding]; other site
1151116013653	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1151116013654	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116013655	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116013656	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116013657	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116013658	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116013659	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116013660	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1151116013661	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1151116013662	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1151116013663	DNA binding residues [nucleotide binding]
1151116013664	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1151116013665	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1151116013666	cell division protein FtsE; Provisional; Region: PRK10908
1151116013667	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116013668	Walker A/P-loop; other site
1151116013669	ATP binding site [chemical binding]; other site
1151116013670	Q-loop/lid; other site
1151116013671	ABC transporter signature motif; other site
1151116013672	Walker B; other site
1151116013673	D-loop; other site
1151116013674	H-loop/switch region; other site
1151116013675	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1151116013676	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1151116013677	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1151116013678	P loop; other site
1151116013679	GTP binding site [chemical binding]; other site
1151116013680	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1151116013681	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116013682	S-adenosylmethionine binding site [chemical binding]; other site
1151116013683	hypothetical protein; Provisional; Region: PRK10910
1151116013684	Predicted membrane protein [Function unknown]; Region: COG3714
1151116013685	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1151116013686	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1151116013687	metal-binding site [ion binding]
1151116013688	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1151116013689	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1151116013690	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1151116013691	CPxP  motif; other site
1151116013692	hypothetical protein; Provisional; Region: PRK11212
1151116013693	hypothetical protein; Provisional; Region: PRK11615
1151116013694	Protein of unknown function (DUF796); Region: DUF796; cl01226
1151116013695	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1151116013696	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116013697	putative substrate translocation pore; other site
1151116013698	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1151116013699	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1151116013700	Walker A/P-loop; other site
1151116013701	ATP binding site [chemical binding]; other site
1151116013702	Q-loop/lid; other site
1151116013703	ABC transporter signature motif; other site
1151116013704	Walker B; other site
1151116013705	D-loop; other site
1151116013706	H-loop/switch region; other site
1151116013707	phosphomannomutase CpsG; Provisional; Region: PRK15414
1151116013708	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1151116013709	active site
1151116013710	substrate binding site [chemical binding]; other site
1151116013711	metal binding site [ion binding]; metal-binding site
1151116013712	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116013713	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116013714	DNA binding site [nucleotide binding]
1151116013715	domain linker motif; other site
1151116013716	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_3; cd06279
1151116013717	putative dimerization interface [polypeptide binding]; other site
1151116013718	putative ligand binding site [chemical binding]; other site
1151116013719	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1151116013720	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1151116013721	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1151116013722	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116013723	dimer interface [polypeptide binding]; other site
1151116013724	putative PBP binding loops; other site
1151116013725	ABC-ATPase subunit interface; other site
1151116013726	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1151116013727	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116013728	dimer interface [polypeptide binding]; other site
1151116013729	conserved gate region; other site
1151116013730	putative PBP binding loops; other site
1151116013731	ABC-ATPase subunit interface; other site
1151116013732	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1151116013733	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1151116013734	active site
1151116013735	catalytic site [active]
1151116013736	Predicted glycosylase [Carbohydrate transport and metabolism]; Region: COG2152
1151116013737	active site
1151116013738	Protein of unknown function (DUF1861); Region: DUF1861; pfam08950
1151116013739	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1151116013740	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1151116013741	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
1151116013742	haemagglutination activity domain; Region: Haemagg_act; pfam05860
1151116013743	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116013744	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116013745	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116013746	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116013747	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116013748	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
1151116013749	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116013750	non-specific DNA binding site [nucleotide binding]; other site
1151116013751	salt bridge; other site
1151116013752	sequence-specific DNA binding site [nucleotide binding]; other site
1151116013753	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
1151116013754	putative hydrolase; Provisional; Region: PRK10976
1151116013755	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116013756	active site
1151116013757	motif I; other site
1151116013758	motif II; other site
1151116013759	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116013760	lysophospholipase L2; Provisional; Region: PRK10749
1151116013761	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1151116013762	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1151116013763	threonine efflux system; Provisional; Region: PRK10229
1151116013764	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1151116013765	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116013766	ATP binding site [chemical binding]; other site
1151116013767	putative Mg++ binding site [ion binding]; other site
1151116013768	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116013769	nucleotide binding region [chemical binding]; other site
1151116013770	ATP-binding site [chemical binding]; other site
1151116013771	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1151116013772	HRDC domain; Region: HRDC; pfam00570
1151116013773	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1151116013774	dimerization interface [polypeptide binding]; other site
1151116013775	substrate binding site [chemical binding]; other site
1151116013776	active site
1151116013777	calcium binding site [ion binding]; other site
1151116013778	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1151116013779	CoenzymeA binding site [chemical binding]; other site
1151116013780	subunit interaction site [polypeptide binding]; other site
1151116013781	PHB binding site; other site
1151116013782	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1151116013783	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1151116013784	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1151116013785	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1151116013786	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1151116013787	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1151116013788	Cl binding site [ion binding]; other site
1151116013789	oligomer interface [polypeptide binding]; other site
1151116013790	cupin fold metalloprotein, WbuC family; Region: cupin_WbuC; TIGR04366
1151116013791	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1151116013792	Part of AAA domain; Region: AAA_19; pfam13245
1151116013793	Family description; Region: UvrD_C_2; pfam13538
1151116013794	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1151116013795	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116013796	motif II; other site
1151116013797	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1151116013798	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1151116013799	active site
1151116013800	Int/Topo IB signature motif; other site
1151116013801	hypothetical protein; Provisional; Region: PRK10963
1151116013802	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1151116013803	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1151116013804	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1151116013805	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1151116013806	adenylate cyclase; Provisional; Region: cyaA; PRK09450
1151116013807	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1151116013808	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1151116013809	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1151116013810	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1151116013811	domain interfaces; other site
1151116013812	active site
1151116013813	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1151116013814	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1151116013815	active site
1151116013816	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1151116013817	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1151116013818	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1151116013819	HemY protein N-terminus; Region: HemY_N; pfam07219
1151116013820	putative transport protein YifK; Provisional; Region: PRK10746
1151116013821	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1151116013822	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1151116013823	putative common antigen polymerase; Provisional; Region: PRK02975
1151116013824	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; cl07929
1151116013825	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1151116013826	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1151116013827	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1151116013828	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1151116013829	inhibitor-cofactor binding pocket; inhibition site
1151116013830	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116013831	catalytic residue [active]
1151116013832	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116013833	Coenzyme A binding pocket [chemical binding]; other site
1151116013834	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1151116013835	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1151116013836	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1151116013837	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1151116013838	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1151116013839	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1151116013840	active site
1151116013841	homodimer interface [polypeptide binding]; other site
1151116013842	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1151116013843	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1151116013844	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1151116013845	Mg++ binding site [ion binding]; other site
1151116013846	putative catalytic motif [active]
1151116013847	substrate binding site [chemical binding]; other site
1151116013848	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1151116013849	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1151116013850	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1151116013851	RNA binding site [nucleotide binding]; other site
1151116013852	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1151116013853	multimer interface [polypeptide binding]; other site
1151116013854	Walker A motif; other site
1151116013855	ATP binding site [chemical binding]; other site
1151116013856	Walker B motif; other site
1151116013857	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1151116013858	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1151116013859	catalytic residues [active]
1151116013860	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1151116013861	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1151116013862	ATP binding site [chemical binding]; other site
1151116013863	Mg++ binding site [ion binding]; other site
1151116013864	motif III; other site
1151116013865	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116013866	nucleotide binding region [chemical binding]; other site
1151116013867	ATP-binding site [chemical binding]; other site
1151116013868	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1151116013869	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1151116013870	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1151116013871	Part of AAA domain; Region: AAA_19; pfam13245
1151116013872	Family description; Region: UvrD_C_2; pfam13538
1151116013873	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
1151116013874	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1151116013875	ketol-acid reductoisomerase; Validated; Region: PRK05225
1151116013876	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1151116013877	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1151116013878	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1151116013879	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116013880	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1151116013881	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1151116013882	putative dimerization interface [polypeptide binding]; other site
1151116013883	threonine dehydratase; Reviewed; Region: PRK09224
1151116013884	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1151116013885	tetramer interface [polypeptide binding]; other site
1151116013886	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116013887	catalytic residue [active]
1151116013888	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1151116013889	putative Ile/Val binding site [chemical binding]; other site
1151116013890	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1151116013891	putative Ile/Val binding site [chemical binding]; other site
1151116013892	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1151116013893	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1151116013894	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1151116013895	homodimer interface [polypeptide binding]; other site
1151116013896	substrate-cofactor binding pocket; other site
1151116013897	catalytic residue [active]
1151116013898	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1151116013899	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1151116013900	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1151116013901	PYR/PP interface [polypeptide binding]; other site
1151116013902	dimer interface [polypeptide binding]; other site
1151116013903	TPP binding site [chemical binding]; other site
1151116013904	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1151116013905	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1151116013906	TPP-binding site [chemical binding]; other site
1151116013907	dimer interface [polypeptide binding]; other site
1151116013908	putative sialic acid transporter; Region: 2A0112; TIGR00891
1151116013909	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116013910	putative substrate translocation pore; other site
1151116013911	putative ATP-dependent protease; Provisional; Region: PRK09862
1151116013912	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1151116013913	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116013914	Walker A motif; other site
1151116013915	ATP binding site [chemical binding]; other site
1151116013916	Walker B motif; other site
1151116013917	arginine finger; other site
1151116013918	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1151116013919	hypothetical protein; Provisional; Region: PRK11027
1151116013920	transcriptional regulator HdfR; Provisional; Region: PRK03601
1151116013921	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116013922	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116013923	dimerization interface [polypeptide binding]; other site
1151116013924	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116013925	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116013926	TM-ABC transporter signature motif; other site
1151116013927	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116013928	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116013929	TM-ABC transporter signature motif; other site
1151116013930	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1151116013931	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116013932	Walker A/P-loop; other site
1151116013933	ATP binding site [chemical binding]; other site
1151116013934	Q-loop/lid; other site
1151116013935	ABC transporter signature motif; other site
1151116013936	Walker B; other site
1151116013937	D-loop; other site
1151116013938	H-loop/switch region; other site
1151116013939	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116013940	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
1151116013941	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1151116013942	putative ligand binding site [chemical binding]; other site
1151116013943	Transposase; Region: HTH_Tnp_1; pfam01527
1151116013944	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1151116013945	HTH-like domain; Region: HTH_21; pfam13276
1151116013946	Integrase core domain; Region: rve; pfam00665
1151116013947	Integrase core domain; Region: rve_3; pfam13683
1151116013948	glutamate racemase; Provisional; Region: PRK00865
1151116013949	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1151116013950	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116013951	N-terminal plug; other site
1151116013952	ligand-binding site [chemical binding]; other site
1151116013953	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1151116013954	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116013955	S-adenosylmethionine binding site [chemical binding]; other site
1151116013956	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1151116013957	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1151116013958	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1151116013959	hypothetical protein; Provisional; Region: PRK11056
1151116013960	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1151116013961	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116013962	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1151116013963	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1151116013964	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1151116013965	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1151116013966	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116013967	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1151116013968	dimerization interface [polypeptide binding]; other site
1151116013969	Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013
1151116013970	catalytic triad [active]
1151116013971	dimer interface [polypeptide binding]; other site
1151116013972	Glutaredoxin (GRX) family, PRX5 hybrid subfamily; composed of hybrid proteins containing peroxiredoxin (PRX) and GRX domains, which is found in some pathogenic bacteria and cyanobacteria. PRXs are thiol-specific antioxidant (TSA) proteins that confer a...; Region: GRX_hybridPRX5; cd03029
1151116013973	GSH binding site [chemical binding]; other site
1151116013974	catalytic residues [active]
1151116013975	argininosuccinate lyase; Provisional; Region: PRK04833
1151116013976	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1151116013977	active sites [active]
1151116013978	tetramer interface [polypeptide binding]; other site
1151116013979	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1151116013980	nucleotide binding site [chemical binding]; other site
1151116013981	N-acetyl-L-glutamate binding site [chemical binding]; other site
1151116013982	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1151116013983	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1151116013984	acetylornithine deacetylase; Provisional; Region: PRK05111
1151116013985	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1151116013986	metal binding site [ion binding]; metal-binding site
1151116013987	putative dimer interface [polypeptide binding]; other site
1151116013988	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1151116013989	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1151116013990	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1151116013991	FAD binding site [chemical binding]; other site
1151116013992	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1151116013993	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1151116013994	putative catalytic residues [active]
1151116013995	putative nucleotide binding site [chemical binding]; other site
1151116013996	putative aspartate binding site [chemical binding]; other site
1151116013997	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1151116013998	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1151116013999	cystathionine gamma-synthase; Provisional; Region: PRK08045
1151116014000	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1151116014001	homodimer interface [polypeptide binding]; other site
1151116014002	substrate-cofactor binding pocket; other site
1151116014003	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116014004	catalytic residue [active]
1151116014005	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1151116014006	dimerization interface [polypeptide binding]; other site
1151116014007	DNA binding site [nucleotide binding]
1151116014008	corepressor binding sites; other site
1151116014009	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1151116014010	primosome assembly protein PriA; Validated; Region: PRK05580
1151116014011	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116014012	ATP binding site [chemical binding]; other site
1151116014013	putative Mg++ binding site [ion binding]; other site
1151116014014	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1151116014015	ATP-binding site [chemical binding]; other site
1151116014016	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116014017	DNA binding site [nucleotide binding]
1151116014018	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1151116014019	domain linker motif; other site
1151116014020	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1151116014021	dimerization interface [polypeptide binding]; other site
1151116014022	ligand binding site [chemical binding]; other site
1151116014023	cell division protein FtsN; Provisional; Region: PRK12757
1151116014024	Sporulation related domain; Region: SPOR; cl10051
1151116014025	Sporulation related domain; Region: SPOR; cl10051
1151116014026	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1151116014027	active site
1151116014028	HslU subunit interaction site [polypeptide binding]; other site
1151116014029	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1151116014030	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116014031	Walker A motif; other site
1151116014032	ATP binding site [chemical binding]; other site
1151116014033	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1151116014034	Walker B motif; other site
1151116014035	arginine finger; other site
1151116014036	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1151116014037	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1151116014038	UbiA prenyltransferase family; Region: UbiA; pfam01040
1151116014039	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1151116014040	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3074
1151116014041	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1151116014042	amphipathic channel; other site
1151116014043	Asn-Pro-Ala signature motifs; other site
1151116014044	glycerol kinase; Provisional; Region: glpK; PRK00047
1151116014045	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1151116014046	N- and C-terminal domain interface [polypeptide binding]; other site
1151116014047	active site
1151116014048	MgATP binding site [chemical binding]; other site
1151116014049	catalytic site [active]
1151116014050	metal binding site [ion binding]; metal-binding site
1151116014051	glycerol binding site [chemical binding]; other site
1151116014052	homotetramer interface [polypeptide binding]; other site
1151116014053	homodimer interface [polypeptide binding]; other site
1151116014054	FBP binding site [chemical binding]; other site
1151116014055	protein IIAGlc interface [polypeptide binding]; other site
1151116014056	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1151116014057	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1151116014058	putative active site [active]
1151116014059	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1151116014060	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116014061	putative substrate translocation pore; other site
1151116014062	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1151116014063	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1151116014064	FAD binding pocket [chemical binding]; other site
1151116014065	FAD binding motif [chemical binding]; other site
1151116014066	phosphate binding motif [ion binding]; other site
1151116014067	beta-alpha-beta structure motif; other site
1151116014068	NAD binding pocket [chemical binding]; other site
1151116014069	Predicted membrane protein [Function unknown]; Region: COG3152
1151116014070	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1151116014071	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1151116014072	triosephosphate isomerase; Provisional; Region: PRK14567
1151116014073	substrate binding site [chemical binding]; other site
1151116014074	dimer interface [polypeptide binding]; other site
1151116014075	catalytic triad [active]
1151116014076	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1151116014077	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116014078	substrate binding pocket [chemical binding]; other site
1151116014079	membrane-bound complex binding site; other site
1151116014080	6-phosphofructokinase; Provisional; Region: PRK03202
1151116014081	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1151116014082	active site
1151116014083	ADP/pyrophosphate binding site [chemical binding]; other site
1151116014084	dimerization interface [polypeptide binding]; other site
1151116014085	allosteric effector site; other site
1151116014086	fructose-1,6-bisphosphate binding site; other site
1151116014087	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1151116014088	dimer interface [polypeptide binding]; other site
1151116014089	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1151116014090	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116014091	active site
1151116014092	phosphorylation site [posttranslational modification]
1151116014093	intermolecular recognition site; other site
1151116014094	dimerization interface [polypeptide binding]; other site
1151116014095	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116014096	DNA binding site [nucleotide binding]
1151116014097	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1151116014098	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1151116014099	dimerization interface [polypeptide binding]; other site
1151116014100	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116014101	dimer interface [polypeptide binding]; other site
1151116014102	phosphorylation site [posttranslational modification]
1151116014103	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116014104	ATP binding site [chemical binding]; other site
1151116014105	Mg2+ binding site [ion binding]; other site
1151116014106	G-X-G motif; other site
1151116014107	putative rRNA methylase; Provisional; Region: PRK10358
1151116014108	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1151116014109	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1151116014110	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1151116014111	trimer interface [polypeptide binding]; other site
1151116014112	active site
1151116014113	substrate binding site [chemical binding]; other site
1151116014114	CoA binding site [chemical binding]; other site
1151116014115	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1151116014116	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1151116014117	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1151116014118	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1151116014119	SecA binding site; other site
1151116014120	Preprotein binding site; other site
1151116014121	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1151116014122	GSH binding site [chemical binding]; other site
1151116014123	catalytic residues [active]
1151116014124	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1151116014125	active site residue [active]
1151116014126	phosphoglyceromutase; Provisional; Region: PRK05434
1151116014127	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1151116014128	AmiB activator; Provisional; Region: PRK11637
1151116014129	Peptidase family M23; Region: Peptidase_M23; pfam01551
1151116014130	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1151116014131	putative active site [active]
1151116014132	NodB motif; other site
1151116014133	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1151116014134	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1151116014135	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1151116014136	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1151116014137	NAD(P) binding site [chemical binding]; other site
1151116014138	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1151116014139	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1151116014140	substrate-cofactor binding pocket; other site
1151116014141	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116014142	catalytic residue [active]
1151116014143	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1151116014144	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1151116014145	NADP binding site [chemical binding]; other site
1151116014146	homopentamer interface [polypeptide binding]; other site
1151116014147	substrate binding site [chemical binding]; other site
1151116014148	active site
1151116014149	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1151116014150	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1151116014151	putative active site [active]
1151116014152	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1151116014153	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1151116014154	putative active site [active]
1151116014155	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1151116014156	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1151116014157	putative active site [active]
1151116014158	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1151116014159	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1151116014160	Ligand binding site; other site
1151116014161	metal-binding site
1151116014162	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1151116014163	O-Antigen ligase; Region: Wzy_C; pfam04932
1151116014164	putative glycosyl transferase; Provisional; Region: PRK10073
1151116014165	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1151116014166	active site
1151116014167	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1151116014168	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1151116014169	putative active site [active]
1151116014170	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1151116014171	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1151116014172	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1151116014173	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1151116014174	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1151116014175	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1151116014176	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1151116014177	putative metal binding site; other site
1151116014178	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1151116014179	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1151116014180	active site
1151116014181	(T/H)XGH motif; other site
1151116014182	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1151116014183	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1151116014184	DNA binding site [nucleotide binding]
1151116014185	catalytic residue [active]
1151116014186	H2TH interface [polypeptide binding]; other site
1151116014187	putative catalytic residues [active]
1151116014188	turnover-facilitating residue; other site
1151116014189	intercalation triad [nucleotide binding]; other site
1151116014190	8OG recognition residue [nucleotide binding]; other site
1151116014191	putative reading head residues; other site
1151116014192	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1151116014193	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1151116014194	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1151116014195	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1151116014196	hypothetical protein; Reviewed; Region: PRK00024
1151116014197	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1151116014198	MPN+ (JAMM) motif; other site
1151116014199	Zinc-binding site [ion binding]; other site
1151116014200	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1151116014201	Flavoprotein; Region: Flavoprotein; pfam02441
1151116014202	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1151116014203	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1151116014204	trimer interface [polypeptide binding]; other site
1151116014205	active site
1151116014206	division inhibitor protein; Provisional; Region: slmA; PRK09480
1151116014207	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116014208	GDYXXLXY protein; Region: GDYXXLXY; pfam14345
1151116014209	Predicted membrane protein (DUF2157); Region: DUF2157; pfam09925
1151116014210	Predicted membrane protein [Function unknown]; Region: COG4984
1151116014211	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1151116014212	active site
1151116014213	ribonuclease PH; Reviewed; Region: rph; PRK00173
1151116014214	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1151116014215	hexamer interface [polypeptide binding]; other site
1151116014216	active site
1151116014217	hypothetical protein; Provisional; Region: PRK11820
1151116014218	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1151116014219	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1151116014220	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK06333
1151116014221	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1151116014222	dimer interface [polypeptide binding]; other site
1151116014223	active site
1151116014224	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116014225	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116014226	Predicted membrane protein [Function unknown]; Region: COG2860
1151116014227	UPF0126 domain; Region: UPF0126; pfam03458
1151116014228	UPF0126 domain; Region: UPF0126; pfam03458
1151116014229	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1151116014230	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1151116014231	nucleotide binding pocket [chemical binding]; other site
1151116014232	K-X-D-G motif; other site
1151116014233	catalytic site [active]
1151116014234	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1151116014235	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1151116014236	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1151116014237	catalytic site [active]
1151116014238	G-X2-G-X-G-K; other site
1151116014239	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1151116014240	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1151116014241	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1151116014242	Zn2+ binding site [ion binding]; other site
1151116014243	Mg2+ binding site [ion binding]; other site
1151116014244	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1151116014245	synthetase active site [active]
1151116014246	NTP binding site [chemical binding]; other site
1151116014247	metal binding site [ion binding]; metal-binding site
1151116014248	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1151116014249	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1151116014250	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1151116014251	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1151116014252	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1151116014253	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1151116014254	Y-family of DNA polymerases; Region: PolY; cl12025
1151116014255	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1151116014256	generic binding surface II; other site
1151116014257	ssDNA binding site; other site
1151116014258	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1151116014259	ATP binding site [chemical binding]; other site
1151116014260	putative Mg++ binding site [ion binding]; other site
1151116014261	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1151116014262	nucleotide binding region [chemical binding]; other site
1151116014263	ATP-binding site [chemical binding]; other site
1151116014264	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1151116014265	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1151116014266	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1151116014267	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1151116014268	AsmA family; Region: AsmA; pfam05170
1151116014269	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116014270	Coenzyme A binding pocket [chemical binding]; other site
1151116014271	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1151116014272	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1151116014273	putative active site [active]
1151116014274	dimerization interface [polypeptide binding]; other site
1151116014275	putative tRNAtyr binding site [nucleotide binding]; other site
1151116014276	hypothetical protein; Reviewed; Region: PRK01637
1151116014277	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1151116014278	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116014279	motif II; other site
1151116014280	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1151116014281	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1151116014282	G1 box; other site
1151116014283	putative GEF interaction site [polypeptide binding]; other site
1151116014284	GTP/Mg2+ binding site [chemical binding]; other site
1151116014285	Switch I region; other site
1151116014286	G2 box; other site
1151116014287	G3 box; other site
1151116014288	Switch II region; other site
1151116014289	G4 box; other site
1151116014290	G5 box; other site
1151116014291	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1151116014292	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1151116014293	glutamine synthetase; Provisional; Region: glnA; PRK09469
1151116014294	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1151116014295	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1151116014296	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1151116014297	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116014298	dimer interface [polypeptide binding]; other site
1151116014299	phosphorylation site [posttranslational modification]
1151116014300	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116014301	ATP binding site [chemical binding]; other site
1151116014302	Mg2+ binding site [ion binding]; other site
1151116014303	G-X-G motif; other site
1151116014304	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1151116014305	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116014306	active site
1151116014307	phosphorylation site [posttranslational modification]
1151116014308	intermolecular recognition site; other site
1151116014309	dimerization interface [polypeptide binding]; other site
1151116014310	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116014311	Walker A motif; other site
1151116014312	ATP binding site [chemical binding]; other site
1151116014313	Walker B motif; other site
1151116014314	arginine finger; other site
1151116014315	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1151116014316	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1151116014317	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116014318	FeS/SAM binding site; other site
1151116014319	HemN C-terminal domain; Region: HemN_C; pfam06969
1151116014320	Der GTPase activator; Provisional; Region: PRK05244
1151116014321	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1151116014322	G1 box; other site
1151116014323	GTP/Mg2+ binding site [chemical binding]; other site
1151116014324	Switch I region; other site
1151116014325	G2 box; other site
1151116014326	G3 box; other site
1151116014327	Switch II region; other site
1151116014328	G4 box; other site
1151116014329	G5 box; other site
1151116014330	DNA polymerase I; Provisional; Region: PRK05755
1151116014331	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1151116014332	active site
1151116014333	metal binding site 1 [ion binding]; metal-binding site
1151116014334	putative 5' ssDNA interaction site; other site
1151116014335	metal binding site 3; metal-binding site
1151116014336	metal binding site 2 [ion binding]; metal-binding site
1151116014337	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1151116014338	putative DNA binding site [nucleotide binding]; other site
1151116014339	putative metal binding site [ion binding]; other site
1151116014340	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1151116014341	active site
1151116014342	catalytic site [active]
1151116014343	substrate binding site [chemical binding]; other site
1151116014344	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1151116014345	active site
1151116014346	DNA binding site [nucleotide binding]
1151116014347	catalytic site [active]
1151116014348	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1151116014349	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1151116014350	catalytic residues [active]
1151116014351	hinge region; other site
1151116014352	alpha helical domain; other site
1151116014353	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1151116014354	serine/threonine protein kinase; Provisional; Region: PRK11768
1151116014355	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1151116014356	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1151116014357	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1151116014358	GTP binding site; other site
1151116014359	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1151116014360	Walker A motif; other site
1151116014361	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116014362	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116014363	DNA-binding site [nucleotide binding]; DNA binding site
1151116014364	FCD domain; Region: FCD; pfam07729
1151116014365	transcriptional repressor RbsR; Provisional; Region: PRK10423
1151116014366	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116014367	DNA binding site [nucleotide binding]
1151116014368	domain linker motif; other site
1151116014369	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1151116014370	dimerization interface [polypeptide binding]; other site
1151116014371	ligand binding site [chemical binding]; other site
1151116014372	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116014373	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1151116014374	substrate binding site [chemical binding]; other site
1151116014375	dimer interface [polypeptide binding]; other site
1151116014376	ATP binding site [chemical binding]; other site
1151116014377	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1151116014378	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1151116014379	ligand binding site [chemical binding]; other site
1151116014380	dimerization interface [polypeptide binding]; other site
1151116014381	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116014382	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116014383	TM-ABC transporter signature motif; other site
1151116014384	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1151116014385	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116014386	Walker A/P-loop; other site
1151116014387	ATP binding site [chemical binding]; other site
1151116014388	Q-loop/lid; other site
1151116014389	ABC transporter signature motif; other site
1151116014390	Walker B; other site
1151116014391	D-loop; other site
1151116014392	H-loop/switch region; other site
1151116014393	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116014394	D-ribose pyranase; Provisional; Region: PRK11797
1151116014395	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1151116014396	potassium uptake protein; Region: kup; TIGR00794
1151116014397	regulatory ATPase RavA; Provisional; Region: PRK13531
1151116014398	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116014399	Walker A motif; other site
1151116014400	ATP binding site [chemical binding]; other site
1151116014401	Walker B motif; other site
1151116014402	arginine finger; other site
1151116014403	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1151116014404	hypothetical protein; Provisional; Region: yieM; PRK10997
1151116014405	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1151116014406	metal ion-dependent adhesion site (MIDAS); other site
1151116014407	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1151116014408	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116014409	putative DNA binding site [nucleotide binding]; other site
1151116014410	putative Zn2+ binding site [ion binding]; other site
1151116014411	AsnC family; Region: AsnC_trans_reg; pfam01037
1151116014412	FMN-binding protein MioC; Provisional; Region: PRK09004
1151116014413	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1151116014414	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
1151116014415	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1151116014416	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1151116014417	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1151116014418	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116014419	S-adenosylmethionine binding site [chemical binding]; other site
1151116014420	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1151116014421	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1151116014422	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1151116014423	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1151116014424	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1151116014425	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1151116014426	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1151116014427	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1151116014428	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1151116014429	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1151116014430	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1151116014431	beta subunit interaction interface [polypeptide binding]; other site
1151116014432	Walker A motif; other site
1151116014433	ATP binding site [chemical binding]; other site
1151116014434	Walker B motif; other site
1151116014435	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1151116014436	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1151116014437	core domain interface [polypeptide binding]; other site
1151116014438	delta subunit interface [polypeptide binding]; other site
1151116014439	epsilon subunit interface [polypeptide binding]; other site
1151116014440	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1151116014441	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1151116014442	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1151116014443	alpha subunit interaction interface [polypeptide binding]; other site
1151116014444	Walker A motif; other site
1151116014445	ATP binding site [chemical binding]; other site
1151116014446	Walker B motif; other site
1151116014447	inhibitor binding site; inhibition site
1151116014448	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1151116014449	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1151116014450	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1151116014451	gamma subunit interface [polypeptide binding]; other site
1151116014452	epsilon subunit interface [polypeptide binding]; other site
1151116014453	LBP interface [polypeptide binding]; other site
1151116014454	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1151116014455	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1151116014456	Substrate binding site; other site
1151116014457	Mg++ binding site; other site
1151116014458	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1151116014459	active site
1151116014460	substrate binding site [chemical binding]; other site
1151116014461	CoA binding site [chemical binding]; other site
1151116014462	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1151116014463	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1151116014464	glutaminase active site [active]
1151116014465	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1151116014466	dimer interface [polypeptide binding]; other site
1151116014467	active site
1151116014468	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1151116014469	dimer interface [polypeptide binding]; other site
1151116014470	active site
1151116014471	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1151116014472	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1151116014473	RNA binding surface [nucleotide binding]; other site
1151116014474	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1151116014475	probable active site [active]
1151116014476	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1151116014477	substrate binding pocket [chemical binding]; other site
1151116014478	membrane-bound complex binding site; other site
1151116014479	hinge residues; other site
1151116014480	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1151116014481	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116014482	dimer interface [polypeptide binding]; other site
1151116014483	conserved gate region; other site
1151116014484	putative PBP binding loops; other site
1151116014485	ABC-ATPase subunit interface; other site
1151116014486	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1151116014487	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116014488	dimer interface [polypeptide binding]; other site
1151116014489	conserved gate region; other site
1151116014490	putative PBP binding loops; other site
1151116014491	ABC-ATPase subunit interface; other site
1151116014492	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1151116014493	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1151116014494	Walker A/P-loop; other site
1151116014495	ATP binding site [chemical binding]; other site
1151116014496	Q-loop/lid; other site
1151116014497	ABC transporter signature motif; other site
1151116014498	Walker B; other site
1151116014499	D-loop; other site
1151116014500	H-loop/switch region; other site
1151116014501	transcriptional regulator PhoU; Provisional; Region: PRK11115
1151116014502	PhoU domain; Region: PhoU; pfam01895
1151116014503	PhoU domain; Region: PhoU; pfam01895
1151116014504	pyrimidine utilization regulatory protein R; Region: RutR; TIGR03613
1151116014505	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116014506	YsiA-like protein, C-terminal region; Region: TetR_C_4; pfam08359
1151116014507	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1151116014508	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1151116014509	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1151116014510	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116014511	motif II; other site
1151116014512	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1151116014513	Predicted flavoprotein [General function prediction only]; Region: COG0431
1151116014514	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1151116014515	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1151116014516	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1151116014517	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116014518	dimer interface [polypeptide binding]; other site
1151116014519	putative CheW interface [polypeptide binding]; other site
1151116014520	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116014521	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116014522	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_8; cd08477
1151116014523	putative effector binding pocket; other site
1151116014524	putative dimerization interface [polypeptide binding]; other site
1151116014525	Lin1944 and related proteins, classical (c) SDRs; Region: Lin1944_like_SDR_c; cd11731
1151116014526	putative NAD(P) binding site [chemical binding]; other site
1151116014527	homodimer interface [polypeptide binding]; other site
1151116014528	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1151116014529	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1151116014530	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1151116014531	G1 box; other site
1151116014532	GTP/Mg2+ binding site [chemical binding]; other site
1151116014533	Switch I region; other site
1151116014534	G2 box; other site
1151116014535	Switch II region; other site
1151116014536	G3 box; other site
1151116014537	G4 box; other site
1151116014538	G5 box; other site
1151116014539	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1151116014540	membrane protein insertase; Provisional; Region: PRK01318
1151116014541	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1151116014542	hypothetical protein; Validated; Region: PRK00041
1151116014543	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1151116014544	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1151116014545	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
1151116014546	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1151116014547	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1151116014548	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116014549	N-terminal plug; other site
1151116014550	ligand-binding site [chemical binding]; other site
1151116014551	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1151116014552	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
1151116014553	active site
1151116014554	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1151116014555	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1151116014556	ligand binding site [chemical binding]; other site
1151116014557	flexible hinge region; other site
1151116014558	YebG protein; Region: YebG; pfam07130
1151116014559	potential frameshift: common BLAST hit: gi|322835132|ref|YP_004215158.1| GCN5-related N-acetyltransferase
1151116014560	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116014561	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116014562	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1151116014563	dimerization interface [polypeptide binding]; other site
1151116014564	substrate binding pocket [chemical binding]; other site
1151116014565	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1151116014566	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_7; cd07585
1151116014567	putative active site [active]
1151116014568	catalytic triad [active]
1151116014569	putative dimer interface [polypeptide binding]; other site
1151116014570	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1151116014571	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1151116014572	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1151116014573	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116014574	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116014575	dimerization interface [polypeptide binding]; other site
1151116014576	trehalase; Provisional; Region: treF; PRK13270
1151116014577	Trehalase; Region: Trehalase; cl17346
1151116014578	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1151116014579	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1151116014580	active site
1151116014581	homotetramer interface [polypeptide binding]; other site
1151116014582	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105
1151116014583	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1151116014584	Protein of unknown function (DUF2493); Region: DUF2493; pfam10686
1151116014585	Arginosuccinate synthase; Region: Arginosuc_synth; cl17227
1151116014586	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1151116014587	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1151116014588	PhoU domain; Region: PhoU; pfam01895
1151116014589	PhoU domain; Region: PhoU; pfam01895
1151116014590	magnesium-transporting ATPase; Provisional; Region: PRK15122
1151116014591	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1151116014592	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1151116014593	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1151116014594	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1151116014595	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1151116014596	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
1151116014597	Right handed beta helix region; Region: Beta_helix; pfam13229
1151116014598	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1151116014599	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1151116014600	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1151116014601	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1151116014602	active site
1151116014603	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1151116014604	Protein of unknown function (DUF796); Region: DUF796; cl01226
1151116014605	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
1151116014606	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1151116014607	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1151116014608	putative active site [active]
1151116014609	metal binding site [ion binding]; metal-binding site
1151116014610	Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305
1151116014611	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1151116014612	putative ligand binding site [chemical binding]; other site
1151116014613	Uncharacterized conserved protein [Function unknown]; Region: COG5276
1151116014614	potential frameshift: common BLAST hit: gi|117621377|ref|YP_856515.1| transporter
1151116014615	2-phosphosulpholactate phosphatase; Region: 2-ph_phosp; cl00895
1151116014616	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116014617	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116014618	putative substrate translocation pore; other site
1151116014619	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116014620	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1151116014621	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1151116014622	inhibitor site; inhibition site
1151116014623	active site
1151116014624	dimer interface [polypeptide binding]; other site
1151116014625	catalytic residue [active]
1151116014626	Virulence factor SrfB; Region: SrfB; pfam07520
1151116014627	Putative bacterial virulence factor; Region: Virul_Fac; pfam10139
1151116014628	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1151116014629	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1151116014630	putative active site; other site
1151116014631	catalytic residue [active]
1151116014632	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1151116014633	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
1151116014634	potential catalytic triad [active]
1151116014635	conserved cys residue [active]
1151116014636	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116014637	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116014638	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
1151116014639	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
1151116014640	nucleotide binding site [chemical binding]; other site
1151116014641	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1151116014642	SBD interface [polypeptide binding]; other site
1151116014643	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
1151116014644	HSP70 interaction site [polypeptide binding]; other site
1151116014645	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
1151116014646	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1151116014647	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1151116014648	active site
1151116014649	Na/Ca binding site [ion binding]; other site
1151116014650	catalytic site [active]
1151116014651	proline/glycine betaine transporter; Provisional; Region: PRK10642
1151116014652	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116014653	putative substrate translocation pore; other site
1151116014654	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1151116014655	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
1151116014656	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1151116014657	hypothetical protein; Provisional; Region: PRK09273
1151116014658	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
1151116014659	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
1151116014660	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1151116014661	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1151116014662	NADP binding site [chemical binding]; other site
1151116014663	homodimer interface [polypeptide binding]; other site
1151116014664	active site
1151116014665	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1151116014666	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116014667	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116014668	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1151116014669	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116014670	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1151116014671	Predicted transcriptional regulator [Transcription]; Region: COG1959
1151116014672	Transcriptional regulator; Region: Rrf2; pfam02082
1151116014673	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1151116014674	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1151116014675	Phosphoinositide 3-kinase (PI3K)-like family, catalytic domain; The PI3K-like catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs); Region: PI3Kc_like; cl00119
1151116014676	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1151116014677	active site
1151116014678	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1151116014679	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1151116014680	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1151116014681	Domain of unknown function (DUF1833); Region: DUF1833; pfam08875
1151116014682	Phage-related minor tail protein [Function unknown]; Region: COG5281
1151116014683	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1151116014684	Minor tail protein T; Region: Phage_tail_T; cl05636
1151116014685	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; cl06106
1151116014686	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1151116014687	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1151116014688	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
1151116014689	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; cl05094
1151116014690	Clp protease; Region: CLP_protease; pfam00574
1151116014691	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1151116014692	oligomer interface [polypeptide binding]; other site
1151116014693	active site residues [active]
1151116014694	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
1151116014695	potential frameshift: common BLAST hit: gi|322835205|ref|YP_004215231.1| phage portal protein, lambda family
1151116014696	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1151116014697	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1151116014698	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1151116014699	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1151116014700	catalytic residues [active]
1151116014701	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
1151116014702	Predicted ATPase [General function prediction only]; Region: COG4637
1151116014703	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116014704	Walker A/P-loop; other site
1151116014705	ATP binding site [chemical binding]; other site
1151116014706	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
1151116014707	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1151116014708	active site
1151116014709	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
1151116014710	Replication protein P; Region: Phage_lambda_P; pfam06992
1151116014711	Helix-turn-helix domain; Region: HTH_36; pfam13730
1151116014712	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
1151116014713	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116014714	non-specific DNA binding site [nucleotide binding]; other site
1151116014715	salt bridge; other site
1151116014716	sequence-specific DNA binding site [nucleotide binding]; other site
1151116014717	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116014718	non-specific DNA binding site [nucleotide binding]; other site
1151116014719	salt bridge; other site
1151116014720	sequence-specific DNA binding site [nucleotide binding]; other site
1151116014721	Predicted transcriptional regulator [Transcription]; Region: COG2932
1151116014722	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1151116014723	Catalytic site [active]
1151116014724	Excisionase-like protein; Region: Exc; pfam07825
1151116014725	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1151116014726	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1151116014727	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1151116014728	dimer interface [polypeptide binding]; other site
1151116014729	active site
1151116014730	Int/Topo IB signature motif; other site
1151116014731	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1151116014732	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1151116014733	trimer interface [polypeptide binding]; other site
1151116014734	eyelet of channel; other site
1151116014735	acetoin reductase; Validated; Region: PRK08643
1151116014736	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
1151116014737	NAD binding site [chemical binding]; other site
1151116014738	homotetramer interface [polypeptide binding]; other site
1151116014739	homodimer interface [polypeptide binding]; other site
1151116014740	active site
1151116014741	substrate binding site [chemical binding]; other site
1151116014742	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1151116014743	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116014744	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1151116014745	Tannase and feruloyl esterase; Region: Tannase; pfam07519
1151116014746	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1151116014747	5-histidylcysteine sulfoxide synthase; Region: ovoA_Nterm; TIGR04344
1151116014748	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
1151116014749	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1151116014750	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116014751	S-adenosylmethionine binding site [chemical binding]; other site
1151116014752	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1151116014753	active site
1151116014754	DNA binding site [nucleotide binding]
1151116014755	Int/Topo IB signature motif; other site
1151116014756	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116014757	PAS domain; Region: PAS_9; pfam13426
1151116014758	putative active site [active]
1151116014759	heme pocket [chemical binding]; other site
1151116014760	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1151116014761	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116014762	dimer interface [polypeptide binding]; other site
1151116014763	putative CheW interface [polypeptide binding]; other site
1151116014764	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1151116014765	ligand binding site [chemical binding]; other site
1151116014766	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1151116014767	dimerization interface [polypeptide binding]; other site
1151116014768	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116014769	dimer interface [polypeptide binding]; other site
1151116014770	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1151116014771	putative CheW interface [polypeptide binding]; other site
1151116014772	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1151116014773	type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355
1151116014774	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1151116014775	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1151116014776	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1151116014777	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1151116014778	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1151116014779	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1151116014780	ligand binding site [chemical binding]; other site
1151116014781	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1151116014782	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1151116014783	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116014784	Walker A motif; other site
1151116014785	ATP binding site [chemical binding]; other site
1151116014786	Walker B motif; other site
1151116014787	arginine finger; other site
1151116014788	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116014789	Walker A motif; other site
1151116014790	ATP binding site [chemical binding]; other site
1151116014791	Walker B motif; other site
1151116014792	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1151116014793	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1151116014794	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1151116014795	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1151116014796	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1151116014797	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
1151116014798	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1151116014799	PAAR motif; Region: PAAR_motif; pfam05488
1151116014800	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1151116014801	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1151116014802	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1151116014803	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1151116014804	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1151116014805	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1151116014806	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1151116014807	potential frameshift: common BLAST hit: gi|322835264|ref|YP_004215290.1| Rhs element Vgr protein
1151116014808	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1151116014809	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1151116014810	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1151116014811	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
1151116014812	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1151116014813	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1151116014814	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1151116014815	ImpA domain protein; Region: DUF3702; pfam12486
1151116014816	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1151116014817	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1151116014818	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1151116014819	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1151116014820	Protein of unknown function (DUF2474); Region: DUF2474; pfam10617
1151116014821	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116014822	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116014823	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1151116014824	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1151116014825	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116014826	putative substrate translocation pore; other site
1151116014827	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116014828	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1151116014829	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
1151116014830	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116014831	Walker A/P-loop; other site
1151116014832	ATP binding site [chemical binding]; other site
1151116014833	Q-loop/lid; other site
1151116014834	ABC transporter signature motif; other site
1151116014835	Walker B; other site
1151116014836	D-loop; other site
1151116014837	H-loop/switch region; other site
1151116014838	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1151116014839	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1151116014840	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116014841	Walker A/P-loop; other site
1151116014842	ATP binding site [chemical binding]; other site
1151116014843	Q-loop/lid; other site
1151116014844	ABC transporter signature motif; other site
1151116014845	Walker B; other site
1151116014846	D-loop; other site
1151116014847	H-loop/switch region; other site
1151116014848	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116014849	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116014850	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116014851	dimer interface [polypeptide binding]; other site
1151116014852	conserved gate region; other site
1151116014853	putative PBP binding loops; other site
1151116014854	ABC-ATPase subunit interface; other site
1151116014855	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116014856	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116014857	dimer interface [polypeptide binding]; other site
1151116014858	conserved gate region; other site
1151116014859	putative PBP binding loops; other site
1151116014860	ABC-ATPase subunit interface; other site
1151116014861	LuxR family transcriptional regulatory, chaperone HchA-associated; Region: reg_near_HchA; TIGR03541
1151116014862	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1151116014863	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1151116014864	DNA binding residues [nucleotide binding]
1151116014865	dimerization interface [polypeptide binding]; other site
1151116014866	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1151116014867	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1151116014868	Cupin; Region: Cupin_6; pfam12852
1151116014869	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116014870	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116014871	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116014872	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1151116014873	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116014874	putative substrate translocation pore; other site
1151116014875	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1151116014876	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1151116014877	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1151116014878	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1151116014879	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116014880	DNA-binding site [nucleotide binding]; DNA binding site
1151116014881	FCD domain; Region: FCD; pfam07729
1151116014882	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1151116014883	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1151116014884	NAD binding site [chemical binding]; other site
1151116014885	homotetramer interface [polypeptide binding]; other site
1151116014886	homodimer interface [polypeptide binding]; other site
1151116014887	active site
1151116014888	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1151116014889	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1151116014890	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1151116014891	Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to...; Region: rTSbeta_L-fuconate_dehydratase; cd03324
1151116014892	putative active site pocket [active]
1151116014893	metal binding site [ion binding]; metal-binding site
1151116014894	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
1151116014895	Amidohydrolase; Region: Amidohydro_2; pfam04909
1151116014896	short chain dehydrogenase; Provisional; Region: PRK08628
1151116014897	classical (c) SDRs; Region: SDR_c; cd05233
1151116014898	NAD(P) binding site [chemical binding]; other site
1151116014899	active site
1151116014900	Domain of unknown function (DUF718); Region: DUF718; pfam05336
1151116014901	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1151116014902	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116014903	putative substrate translocation pore; other site
1151116014904	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1151116014905	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116014906	dimerization interface [polypeptide binding]; other site
1151116014907	putative DNA binding site [nucleotide binding]; other site
1151116014908	putative Zn2+ binding site [ion binding]; other site
1151116014909	ACT domain-containing protein [General function prediction only]; Region: COG4747
1151116014910	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1151116014911	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1151116014912	Domain of unknown function (DUF1852); Region: DUF1852; pfam08908
1151116014913	methionine synthase; Provisional; Region: PRK01207
1151116014914	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1151116014915	substrate binding site [chemical binding]; other site
1151116014916	THF binding site; other site
1151116014917	zinc-binding site [ion binding]; other site
1151116014918	YceI-like domain; Region: YceI; pfam04264
1151116014919	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1151116014920	Zn2+ binding site [ion binding]; other site
1151116014921	Mg2+ binding site [ion binding]; other site
1151116014922	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1151116014923	DNA binding site [nucleotide binding]
1151116014924	YfaZ precursor; Region: YfaZ; pfam07437
1151116014925	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1151116014926	methionine sulfoxide reductase A; Provisional; Region: PRK13014
1151116014927	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1151116014928	SelR domain; Region: SelR; pfam01641
1151116014929	alpha-glucosidase; Provisional; Region: PRK10426
1151116014930	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1151116014931	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
1151116014932	putative active site [active]
1151116014933	putative catalytic site [active]
1151116014934	putative symporter YagG; Provisional; Region: PRK09669
1151116014935	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1151116014936	MarR family; Region: MarR_2; cl17246
1151116014937	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1151116014938	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1151116014939	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
1151116014940	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1151116014941	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1151116014942	active site
1151116014943	metal binding site [ion binding]; metal-binding site
1151116014944	nudix motif; other site
1151116014945	Adenylate kinase and related kinases [Nucleotide transport and metabolism]; Region: Adk; COG0563
1151116014946	AAA domain; Region: AAA_17; pfam13207
1151116014947	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1151116014948	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1151116014949	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1151116014950	NADP binding site [chemical binding]; other site
1151116014951	Predicted transcriptional regulators [Transcription]; Region: COG1733
1151116014952	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1151116014953	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3224
1151116014954	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1151116014955	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1151116014956	active site
1151116014957	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1151116014958	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116014959	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1151116014960	dimerization interface [polypeptide binding]; other site
1151116014961	substrate binding pocket [chemical binding]; other site
1151116014962	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1151116014963	EamA-like transporter family; Region: EamA; cl17759
1151116014964	EamA-like transporter family; Region: EamA; pfam00892
1151116014965	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1151116014966	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1151116014967	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1151116014968	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1151116014969	putative active site [active]
1151116014970	YdjC motif; other site
1151116014971	Mg binding site [ion binding]; other site
1151116014972	putative homodimer interface [polypeptide binding]; other site
1151116014973	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1151116014974	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1151116014975	NAD binding site [chemical binding]; other site
1151116014976	sugar binding site [chemical binding]; other site
1151116014977	divalent metal binding site [ion binding]; other site
1151116014978	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1151116014979	dimer interface [polypeptide binding]; other site
1151116014980	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1151116014981	Cupin domain; Region: Cupin_2; pfam07883
1151116014982	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116014983	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1151116014984	methionine cluster; other site
1151116014985	active site
1151116014986	phosphorylation site [posttranslational modification]
1151116014987	metal binding site [ion binding]; metal-binding site
1151116014988	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1151116014989	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1151116014990	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
1151116014991	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116014992	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116014993	DNA binding site [nucleotide binding]
1151116014994	domain linker motif; other site
1151116014995	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1151116014996	putative dimerization interface [polypeptide binding]; other site
1151116014997	putative ligand binding site [chemical binding]; other site
1151116014998	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
1151116014999	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1151116015000	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1151116015001	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1151116015002	Cytochrome c; Region: Cytochrom_C; cl11414
1151116015003	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1151116015004	Cytochrome c; Region: Cytochrom_C; pfam00034
1151116015005	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1151116015006	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116015007	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116015008	putative substrate translocation pore; other site
1151116015009	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116015010	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116015011	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116015012	putative effector binding pocket; other site
1151116015013	dimerization interface [polypeptide binding]; other site
1151116015014	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1151116015015	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1151116015016	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1151116015017	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1151116015018	Sensors of blue-light using FAD; Region: BLUF; smart01034
1151116015019	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1151116015020	tellurite resistance protein TehB; Provisional; Region: PRK11207
1151116015021	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1151116015022	S-adenosylmethionine binding site [chemical binding]; other site
1151116015023	CsbD-like; Region: CsbD; pfam05532
1151116015024	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1151116015025	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1151116015026	Uncharacterized small protein (DUF2158); Region: DUF2158; cl02293
1151116015027	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1151116015028	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1151116015029	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1151116015030	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1151116015031	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1151116015032	pyridoxal-dependent decarboxylase, exosortase A system-associated; Region: dCO2ase_PEP1; TIGR03099
1151116015033	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Btrk Decarboxylase; Region: PLPDE_III_Btrk_like; cd06839
1151116015034	dimer interface [polypeptide binding]; other site
1151116015035	active site
1151116015036	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1151116015037	catalytic residues [active]
1151116015038	substrate binding site [chemical binding]; other site
1151116015039	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
1151116015040	active site
1151116015041	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1151116015042	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1151116015043	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1151116015044	acyl-activating enzyme (AAE) consensus motif; other site
1151116015045	AMP binding site [chemical binding]; other site
1151116015046	active site
1151116015047	CoA binding site [chemical binding]; other site
1151116015048	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
1151116015049	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
1151116015050	acyl-activating enzyme (AAE) consensus motif; other site
1151116015051	AMP binding site [chemical binding]; other site
1151116015052	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1151116015053	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
1151116015054	acyl-activating enzyme (AAE) consensus motif; other site
1151116015055	AMP binding site [chemical binding]; other site
1151116015056	active site
1151116015057	CoA binding site [chemical binding]; other site
1151116015058	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1151116015059	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1151116015060	active site
1151116015061	metal binding site [ion binding]; metal-binding site
1151116015062	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1151116015063	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1151116015064	active site
1151116015065	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1151116015066	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
1151116015067	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; Region: ACP_syn_III_C; pfam08541
1151116015068	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1151116015069	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1151116015070	active site
1151116015071	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1151116015072	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
1151116015073	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1151116015074	Cytochrome P450; Region: p450; cl12078
1151116015075	natural product biosynthesis luciferase-like monooxygenase domain; Region: seco_metab_LLM; TIGR04020
1151116015076	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1151116015077	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1151116015078	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1151116015079	PAS domain; Region: PAS; smart00091
1151116015080	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1151116015081	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1151116015082	dimer interface [polypeptide binding]; other site
1151116015083	phosphorylation site [posttranslational modification]
1151116015084	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116015085	ATP binding site [chemical binding]; other site
1151116015086	Mg2+ binding site [ion binding]; other site
1151116015087	G-X-G motif; other site
1151116015088	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1151116015089	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116015090	active site
1151116015091	phosphorylation site [posttranslational modification]
1151116015092	intermolecular recognition site; other site
1151116015093	dimerization interface [polypeptide binding]; other site
1151116015094	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116015095	Walker A motif; other site
1151116015096	ATP binding site [chemical binding]; other site
1151116015097	Walker B motif; other site
1151116015098	arginine finger; other site
1151116015099	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1151116015100	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
1151116015101	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1151116015102	FtsX-like permease family; Region: FtsX; pfam02687
1151116015103	FtsX-like permease family; Region: FtsX; pfam02687
1151116015104	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1151116015105	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1151116015106	Walker A/P-loop; other site
1151116015107	ATP binding site [chemical binding]; other site
1151116015108	Q-loop/lid; other site
1151116015109	ABC transporter signature motif; other site
1151116015110	Walker B; other site
1151116015111	D-loop; other site
1151116015112	H-loop/switch region; other site
1151116015113	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1151116015114	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116015115	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116015116	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116015117	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116015118	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1151116015119	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1151116015120	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1151116015121	putative efflux protein, MATE family; Region: matE; TIGR00797
1151116015122	acyl carrier protein; Provisional; Region: PRK07639
1151116015123	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; Region: ACP_syn_III_C; pfam08541
1151116015124	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1151116015125	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015126	Walker A/P-loop; other site
1151116015127	ATP binding site [chemical binding]; other site
1151116015128	Q-loop/lid; other site
1151116015129	ABC transporter signature motif; other site
1151116015130	Walker B; other site
1151116015131	D-loop; other site
1151116015132	H-loop/switch region; other site
1151116015133	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1151116015134	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015135	Walker A/P-loop; other site
1151116015136	ATP binding site [chemical binding]; other site
1151116015137	Q-loop/lid; other site
1151116015138	ABC transporter signature motif; other site
1151116015139	Walker B; other site
1151116015140	D-loop; other site
1151116015141	H-loop/switch region; other site
1151116015142	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1151116015143	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1151116015144	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015145	dimer interface [polypeptide binding]; other site
1151116015146	conserved gate region; other site
1151116015147	putative PBP binding loops; other site
1151116015148	ABC-ATPase subunit interface; other site
1151116015149	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116015150	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015151	dimer interface [polypeptide binding]; other site
1151116015152	conserved gate region; other site
1151116015153	putative PBP binding loops; other site
1151116015154	ABC-ATPase subunit interface; other site
1151116015155	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1151116015156	active site
1151116015157	tetramer interface [polypeptide binding]; other site
1151116015158	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1151116015159	active site
1151116015160	tetramer interface [polypeptide binding]; other site
1151116015161	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1151116015162	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1151116015163	inhibitor site; inhibition site
1151116015164	active site
1151116015165	dimer interface [polypeptide binding]; other site
1151116015166	catalytic residue [active]
1151116015167	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116015168	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_2; cd08498
1151116015169	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1151116015170	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116015171	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116015172	dimerization interface [polypeptide binding]; other site
1151116015173	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1151116015174	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1151116015175	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1151116015176	Trp docking motif [polypeptide binding]; other site
1151116015177	putative active site [active]
1151116015178	HipA N-terminal domain; Region: couple_hipA; TIGR03071
1151116015179	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
1151116015180	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1151116015181	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1151116015182	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1151116015183	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116015184	non-specific DNA binding site [nucleotide binding]; other site
1151116015185	salt bridge; other site
1151116015186	sequence-specific DNA binding site [nucleotide binding]; other site
1151116015187	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1151116015188	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116015189	DNA-binding site [nucleotide binding]; DNA binding site
1151116015190	UTRA domain; Region: UTRA; pfam07702
1151116015191	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1151116015192	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1151116015193	metal binding site [ion binding]; metal-binding site
1151116015194	substrate binding pocket [chemical binding]; other site
1151116015195	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1151116015196	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116015197	active site turn [active]
1151116015198	phosphorylation site [posttranslational modification]
1151116015199	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116015200	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1151116015201	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1151116015202	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116015203	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116015204	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116015205	dimerization interface [polypeptide binding]; other site
1151116015206	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1151116015207	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015208	Walker A/P-loop; other site
1151116015209	ATP binding site [chemical binding]; other site
1151116015210	Q-loop/lid; other site
1151116015211	ABC transporter signature motif; other site
1151116015212	Walker B; other site
1151116015213	D-loop; other site
1151116015214	H-loop/switch region; other site
1151116015215	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1151116015216	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1151116015217	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015218	Walker A/P-loop; other site
1151116015219	ATP binding site [chemical binding]; other site
1151116015220	Q-loop/lid; other site
1151116015221	ABC transporter signature motif; other site
1151116015222	Walker B; other site
1151116015223	D-loop; other site
1151116015224	H-loop/switch region; other site
1151116015225	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1151116015226	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116015227	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1151116015228	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015229	dimer interface [polypeptide binding]; other site
1151116015230	conserved gate region; other site
1151116015231	putative PBP binding loops; other site
1151116015232	ABC-ATPase subunit interface; other site
1151116015233	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116015234	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015235	dimer interface [polypeptide binding]; other site
1151116015236	conserved gate region; other site
1151116015237	putative PBP binding loops; other site
1151116015238	ABC-ATPase subunit interface; other site
1151116015239	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116015240	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
1151116015241	Initiator Replication protein; Region: Rep_3; pfam01051
1151116015242	ParG; Region: ParG; pfam09274
1151116015243	ParA-like protein; Provisional; Region: PHA02518
1151116015244	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1151116015245	Magnesium ion binding site [ion binding]; other site
1151116015246	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1151116015247	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1151116015248	Walker A/P-loop; other site
1151116015249	ATP binding site [chemical binding]; other site
1151116015250	Q-loop/lid; other site
1151116015251	ABC transporter signature motif; other site
1151116015252	Walker B; other site
1151116015253	D-loop; other site
1151116015254	H-loop/switch region; other site
1151116015255	TOBE domain; Region: TOBE_2; pfam08402
1151116015256	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1151116015257	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116015258	DNA-binding site [nucleotide binding]; DNA binding site
1151116015259	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1151116015260	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116015261	homodimer interface [polypeptide binding]; other site
1151116015262	catalytic residue [active]
1151116015263	4-aminobutyrate aminotransferase; Provisional; Region: PRK06777
1151116015264	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1151116015265	inhibitor-cofactor binding pocket; inhibition site
1151116015266	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116015267	catalytic residue [active]
1151116015268	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1151116015269	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1151116015270	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015271	dimer interface [polypeptide binding]; other site
1151116015272	conserved gate region; other site
1151116015273	putative PBP binding loops; other site
1151116015274	ABC-ATPase subunit interface; other site
1151116015275	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1151116015276	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015277	dimer interface [polypeptide binding]; other site
1151116015278	conserved gate region; other site
1151116015279	putative PBP binding loops; other site
1151116015280	ABC-ATPase subunit interface; other site
1151116015281	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1151116015282	classical (c) SDRs; Region: SDR_c; cd05233
1151116015283	NAD(P) binding site [chemical binding]; other site
1151116015284	active site
1151116015285	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1151116015286	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1151116015287	active site
1151116015288	ATP binding site [chemical binding]; other site
1151116015289	substrate binding site [chemical binding]; other site
1151116015290	4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160
1151116015291	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1151116015292	inhibitor-cofactor binding pocket; inhibition site
1151116015293	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116015294	catalytic residue [active]
1151116015295	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116015296	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116015297	metal binding site [ion binding]; metal-binding site
1151116015298	active site
1151116015299	I-site; other site
1151116015300	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1151116015301	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116015302	DNA-binding site [nucleotide binding]; DNA binding site
1151116015303	FCD domain; Region: FCD; pfam07729
1151116015304	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1151116015305	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116015306	putative substrate translocation pore; other site
1151116015307	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116015308	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1151116015309	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1151116015310	putative [Fe4-S4] binding site [ion binding]; other site
1151116015311	putative molybdopterin cofactor binding site [chemical binding]; other site
1151116015312	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1151116015313	putative molybdopterin cofactor binding site; other site
1151116015314	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1151116015315	4Fe-4S binding domain; Region: Fer4; pfam00037
1151116015316	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1151116015317	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1151116015318	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1151116015319	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1151116015320	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
1151116015321	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
1151116015322	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
1151116015323	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
1151116015324	zinc-ribbon domain; Region: zf-ribbon_3; cl11198
1151116015325	TM2 domain; Region: TM2; pfam05154
1151116015326	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1151116015327	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1151116015328	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1151116015329	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1151116015330	NAD(P) binding site [chemical binding]; other site
1151116015331	catalytic residues [active]
1151116015332	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116015333	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116015334	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1151116015335	putative dimerization interface [polypeptide binding]; other site
1151116015336	H-NS histone family; Region: Histone_HNS; pfam00816
1151116015337	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1151116015338	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1151116015339	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1151116015340	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1151116015341	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1151116015342	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1151116015343	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1151116015344	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1151116015345	Fic/DOC family; Region: Fic; pfam02661
1151116015346	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116015347	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116015348	TM-ABC transporter signature motif; other site
1151116015349	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116015350	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1151116015351	TM-ABC transporter signature motif; other site
1151116015352	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1151116015353	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1151116015354	Walker A/P-loop; other site
1151116015355	ATP binding site [chemical binding]; other site
1151116015356	Q-loop/lid; other site
1151116015357	ABC transporter signature motif; other site
1151116015358	Walker B; other site
1151116015359	D-loop; other site
1151116015360	H-loop/switch region; other site
1151116015361	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1151116015362	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1151116015363	rhamnose ABC transporter, rhamnose-binding protein; Region: RhaS; TIGR02637
1151116015364	ligand binding site [chemical binding]; other site
1151116015365	transcriptional activator RhaS; Provisional; Region: PRK13503
1151116015366	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1151116015367	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116015368	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
1151116015369	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1151116015370	NAD binding site [chemical binding]; other site
1151116015371	catalytic residues [active]
1151116015372	substrate binding site [chemical binding]; other site
1151116015373	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1151116015374	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1151116015375	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
1151116015376	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
1151116015377	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1151116015378	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1151116015379	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116015380	N-terminal plug; other site
1151116015381	ligand-binding site [chemical binding]; other site
1151116015382	Predicted integral membrane protein (DUF2269); Region: DUF2269; cl02335
1151116015383	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1151116015384	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1151116015385	Trp docking motif [polypeptide binding]; other site
1151116015386	putative active site [active]
1151116015387	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1151116015388	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1151116015389	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116015390	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116015391	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1151116015392	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116015393	NAD(P) binding site [chemical binding]; other site
1151116015394	active site
1151116015395	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
1151116015396	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1151116015397	Uncharacterized conserved protein [Function unknown]; Region: COG3268
1151116015398	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1151116015399	NAD(P) binding site [chemical binding]; other site
1151116015400	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1151116015401	dimerization interface [polypeptide binding]; other site
1151116015402	substrate binding pocket [chemical binding]; other site
1151116015403	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1151116015404	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3813
1151116015405	Protein of unknown function (DUF1272); Region: DUF1272; pfam06906
1151116015406	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1151116015407	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_11; cd07261
1151116015408	putative dimer interface [polypeptide binding]; other site
1151116015409	HTH domain; Region: HTH_11; pfam08279
1151116015410	Predicted transcriptional regulator [Transcription]; Region: COG2378
1151116015411	WYL domain; Region: WYL; pfam13280
1151116015412	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116015413	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116015414	putative substrate translocation pore; other site
1151116015415	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116015416	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116015417	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_1; cd08460
1151116015418	putative substrate binding pocket [chemical binding]; other site
1151116015419	putative dimerization interface [polypeptide binding]; other site
1151116015420	exodeoxyribonuclease X; Provisional; Region: PRK07983
1151116015421	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1151116015422	active site
1151116015423	catalytic site [active]
1151116015424	substrate binding site [chemical binding]; other site
1151116015425	Protein of unknown function (DUF3820); Region: DUF3820; cl01411
1151116015426	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1151116015427	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 4. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_4; cd03329
1151116015428	putative active site pocket [active]
1151116015429	metal binding site [ion binding]; metal-binding site
1151116015430	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116015431	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
1151116015432	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116015433	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015434	dimer interface [polypeptide binding]; other site
1151116015435	conserved gate region; other site
1151116015436	putative PBP binding loops; other site
1151116015437	ABC-ATPase subunit interface; other site
1151116015438	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116015439	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1151116015440	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015441	dimer interface [polypeptide binding]; other site
1151116015442	conserved gate region; other site
1151116015443	ABC-ATPase subunit interface; other site
1151116015444	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116015445	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015446	Walker A/P-loop; other site
1151116015447	ATP binding site [chemical binding]; other site
1151116015448	Q-loop/lid; other site
1151116015449	ABC transporter signature motif; other site
1151116015450	Walker B; other site
1151116015451	D-loop; other site
1151116015452	H-loop/switch region; other site
1151116015453	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116015454	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116015455	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015456	Walker A/P-loop; other site
1151116015457	ATP binding site [chemical binding]; other site
1151116015458	Q-loop/lid; other site
1151116015459	ABC transporter signature motif; other site
1151116015460	Walker B; other site
1151116015461	D-loop; other site
1151116015462	H-loop/switch region; other site
1151116015463	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1151116015464	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1151116015465	Bacterial protein of unknown function (DUF879); Region: DUF879; cl15462
1151116015466	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1151116015467	potential frameshift: common BLAST hit: gi|322835481|ref|YP_004215507.1| ImcF domain protein
1151116015468	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1151116015469	PAAR motif; Region: PAAR_motif; pfam05488
1151116015470	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1151116015471	Sel1-like repeats; Region: SEL1; smart00671
1151116015472	Sel1-like repeats; Region: SEL1; smart00671
1151116015473	Sel1-like repeats; Region: SEL1; smart00671
1151116015474	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1151116015475	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1151116015476	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1151116015477	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1151116015478	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
1151116015479	MarR family; Region: MarR_2; pfam12802
1151116015480	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116015481	Coenzyme A binding pocket [chemical binding]; other site
1151116015482	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116015483	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1151116015484	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_3; cd08490
1151116015485	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1151116015486	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116015487	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1151116015488	putative substrate translocation pore; other site
1151116015489	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116015490	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015491	Walker A/P-loop; other site
1151116015492	ATP binding site [chemical binding]; other site
1151116015493	Q-loop/lid; other site
1151116015494	ABC transporter signature motif; other site
1151116015495	Walker B; other site
1151116015496	D-loop; other site
1151116015497	H-loop/switch region; other site
1151116015498	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
1151116015499	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015500	Walker A/P-loop; other site
1151116015501	ATP binding site [chemical binding]; other site
1151116015502	Q-loop/lid; other site
1151116015503	ABC transporter signature motif; other site
1151116015504	Walker B; other site
1151116015505	D-loop; other site
1151116015506	H-loop/switch region; other site
1151116015507	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1151116015508	D-fructose-responsive transcription factor; Region: fruct_sucro_rep; TIGR02417
1151116015509	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116015510	DNA binding site [nucleotide binding]
1151116015511	domain linker motif; other site
1151116015512	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1151116015513	dimerization interface [polypeptide binding]; other site
1151116015514	ligand binding site [chemical binding]; other site
1151116015515	potential frameshift: common BLAST hit: gi|322835496|ref|YP_004215522.1| sucrose-6-phosphate hydrolase
1151116015516	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1151116015517	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1151116015518	active site turn [active]
1151116015519	phosphorylation site [posttranslational modification]
1151116015520	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1151116015521	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1151116015522	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1151116015523	trimer interface; other site
1151116015524	sugar binding site [chemical binding]; other site
1151116015525	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116015526	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1151116015527	putative substrate binding site [chemical binding]; other site
1151116015528	putative ATP binding site [chemical binding]; other site
1151116015529	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1151116015530	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116015531	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116015532	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116015533	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116015534	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1151116015535	Surface antigen; Region: Bac_surface_Ag; pfam01103
1151116015536	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
1151116015537	methionine sulfoxide reductase B; Provisional; Region: PRK05508
1151116015538	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1151116015539	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
1151116015540	Protein export membrane protein; Region: SecD_SecF; cl14618
1151116015541	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1151116015542	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116015543	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116015544	Predicted transcriptional regulators [Transcription]; Region: COG1695
1151116015545	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1151116015546	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1151116015547	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1151116015548	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1151116015549	mce related protein; Region: MCE; pfam02470
1151116015550	mce related protein; Region: MCE; pfam02470
1151116015551	mce related protein; Region: MCE; pfam02470
1151116015552	Paraquat-inducible protein A; Region: PqiA; pfam04403
1151116015553	Paraquat-inducible protein A; Region: PqiA; pfam04403
1151116015554	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1151116015555	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1151116015556	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116015557	N-terminal plug; other site
1151116015558	ligand-binding site [chemical binding]; other site
1151116015559	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116015560	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116015561	AefR-like transcriptional repressor, C-terminal region; Region: TetR_C_7; pfam14246
1151116015562	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1151116015563	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1151116015564	FAD binding pocket [chemical binding]; other site
1151116015565	FAD binding motif [chemical binding]; other site
1151116015566	phosphate binding motif [ion binding]; other site
1151116015567	NAD binding pocket [chemical binding]; other site
1151116015568	Predicted transcriptional regulators [Transcription]; Region: COG1695
1151116015569	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1151116015570	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1151116015571	active site
1151116015572	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
1151116015573	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
1151116015574	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1151116015575	Moco binding site; other site
1151116015576	metal coordination site [ion binding]; other site
1151116015577	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1151116015578	Cytochrome b(N-terminal)/b6/petB; Region: Cytochrom_B_N; pfam00033
1151116015579	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1151116015580	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116015581	active site
1151116015582	phosphorylation site [posttranslational modification]
1151116015583	intermolecular recognition site; other site
1151116015584	dimerization interface [polypeptide binding]; other site
1151116015585	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1151116015586	DNA binding site [nucleotide binding]
1151116015587	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1151116015588	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1151116015589	dimer interface [polypeptide binding]; other site
1151116015590	phosphorylation site [posttranslational modification]
1151116015591	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116015592	ATP binding site [chemical binding]; other site
1151116015593	Mg2+ binding site [ion binding]; other site
1151116015594	G-X-G motif; other site
1151116015595	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; pfam01977
1151116015596	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116015597	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116015598	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116015599	dimerization interface [polypeptide binding]; other site
1151116015600	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1151116015601	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1151116015602	non-specific DNA binding site [nucleotide binding]; other site
1151116015603	salt bridge; other site
1151116015604	sequence-specific DNA binding site [nucleotide binding]; other site
1151116015605	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
1151116015606	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1151116015607	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1151116015608	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
1151116015609	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1151116015610	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1151116015611	NAD(P) binding site [chemical binding]; other site
1151116015612	putative active site [active]
1151116015613	putative heme utilization carrier protein HutX; Region: HutX; TIGR04108
1151116015614	coproporphyrinogen III oxidase; Provisional; Region: PRK09058
1151116015615	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116015616	FeS/SAM binding site; other site
1151116015617	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1151116015618	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116015619	Walker B; other site
1151116015620	D-loop; other site
1151116015621	H-loop/switch region; other site
1151116015622	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1151116015623	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1151116015624	phosphate binding site [ion binding]; other site
1151116015625	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116015626	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116015627	metal binding site [ion binding]; metal-binding site
1151116015628	active site
1151116015629	I-site; other site
1151116015630	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1151116015631	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1151116015632	pyrroloquinoline quinone biosynthesis protein PqqE; Provisional; Region: PRK05301
1151116015633	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116015634	FeS/SAM binding site; other site
1151116015635	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1151116015636	pyrroloquinoline quinone biosynthesis protein PqqD; Provisional; Region: PRK02079
1151116015637	pyrroloquinoline quinone biosynthesis protein PqqC; Provisional; Region: PRK05157
1151116015638	pyrroloquinoline quinone biosynthesis protein PqqB; Provisional; Region: PRK05184
1151116015639	coenzyme PQQ biosynthesis protein B; Region: PQQ_syn_pqqB; TIGR02108
1151116015640	coenzyme PQQ synthesis protein PqqA; Provisional; Region: pqqA; PRK00284
1151116015641	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
1151116015642	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
1151116015643	active site
1151116015644	dimer interface [polypeptide binding]; other site
1151116015645	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1151116015646	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116015647	N-terminal plug; other site
1151116015648	ligand-binding site [chemical binding]; other site
1151116015649	Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) [Amino acid transport and metabolism]; Region: MHT1; COG2040
1151116015650	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1151116015651	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1151116015652	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_17; cd08503
1151116015653	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1151116015654	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015655	dimer interface [polypeptide binding]; other site
1151116015656	conserved gate region; other site
1151116015657	putative PBP binding loops; other site
1151116015658	ABC-ATPase subunit interface; other site
1151116015659	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1151116015660	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1151116015661	dimer interface [polypeptide binding]; other site
1151116015662	conserved gate region; other site
1151116015663	ABC-ATPase subunit interface; other site
1151116015664	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015665	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1151116015666	Walker A/P-loop; other site
1151116015667	ATP binding site [chemical binding]; other site
1151116015668	Q-loop/lid; other site
1151116015669	ABC transporter signature motif; other site
1151116015670	Walker B; other site
1151116015671	D-loop; other site
1151116015672	H-loop/switch region; other site
1151116015673	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1151116015674	Walker A/P-loop; other site
1151116015675	ATP binding site [chemical binding]; other site
1151116015676	Q-loop/lid; other site
1151116015677	ABC transporter signature motif; other site
1151116015678	Walker B; other site
1151116015679	D-loop; other site
1151116015680	H-loop/switch region; other site
1151116015681	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1151116015682	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1151116015683	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1151116015684	dimerization interface [polypeptide binding]; other site
1151116015685	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1151116015686	dimer interface [polypeptide binding]; other site
1151116015687	putative CheW interface [polypeptide binding]; other site
1151116015688	beta-lactamase TEM; Provisional; Region: PRK15442
1151116015689	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1151116015690	diaminobutyrate--2-oxoglutarate aminotransferase; Provisional; Region: PRK06931
1151116015691	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1151116015692	inhibitor-cofactor binding pocket; inhibition site
1151116015693	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116015694	catalytic residue [active]
1151116015695	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
1151116015696	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1151116015697	catalytic residue [active]
1151116015698	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1151116015699	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1151116015700	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
1151116015701	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1151116015702	active site
1151116015703	catalytic site [active]
1151116015704	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
1151116015705	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
1151116015706	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
1151116015707	catalytic site [active]
1151116015708	active site
1151116015709	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1151116015710	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1151116015711	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1151116015712	intersubunit interface [polypeptide binding]; other site
1151116015713	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1151116015714	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1151116015715	C-terminal domain interface [polypeptide binding]; other site
1151116015716	GSH binding site (G-site) [chemical binding]; other site
1151116015717	dimer interface [polypeptide binding]; other site
1151116015718	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1151116015719	dimer interface [polypeptide binding]; other site
1151116015720	N-terminal domain interface [polypeptide binding]; other site
1151116015721	putative substrate binding pocket (H-site) [chemical binding]; other site
1151116015722	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1151116015723	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1151116015724	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116015725	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116015726	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1151116015727	dimerization interface [polypeptide binding]; other site
1151116015728	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1151116015729	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1151116015730	GAF domain; Region: GAF; cl17456
1151116015731	Histidine kinase; Region: His_kinase; pfam06580
1151116015732	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116015733	ATP binding site [chemical binding]; other site
1151116015734	Mg2+ binding site [ion binding]; other site
1151116015735	G-X-G motif; other site
1151116015736	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1151116015737	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116015738	active site
1151116015739	phosphorylation site [posttranslational modification]
1151116015740	intermolecular recognition site; other site
1151116015741	dimerization interface [polypeptide binding]; other site
1151116015742	LytTr DNA-binding domain; Region: LytTR; smart00850
1151116015743	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1151116015744	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1151116015745	P-loop, Walker A motif; other site
1151116015746	Base recognition motif; other site
1151116015747	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1151116015748	Uncharacterized small protein [Function unknown]; Region: COG2879
1151116015749	carbon starvation protein A; Provisional; Region: PRK15015
1151116015750	Carbon starvation protein CstA; Region: CstA; pfam02554
1151116015751	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1151116015752	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1151116015753	beta-galactosidase; Region: BGL; TIGR03356
1151116015754	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1151116015755	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1151116015756	active site
1151116015757	DNA binding site [nucleotide binding]
1151116015758	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1151116015759	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1151116015760	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1151116015761	Catalytic site [active]
1151116015762	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1151116015763	Glyoxalase-like domain; Region: Glyoxalase_3; pfam13468
1151116015764	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1151116015765	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1151116015766	Walker A/P-loop; other site
1151116015767	ATP binding site [chemical binding]; other site
1151116015768	Q-loop/lid; other site
1151116015769	ABC transporter signature motif; other site
1151116015770	Walker B; other site
1151116015771	D-loop; other site
1151116015772	H-loop/switch region; other site
1151116015773	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1151116015774	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1151116015775	Walker A/P-loop; other site
1151116015776	ATP binding site [chemical binding]; other site
1151116015777	Q-loop/lid; other site
1151116015778	ABC transporter signature motif; other site
1151116015779	Walker B; other site
1151116015780	D-loop; other site
1151116015781	H-loop/switch region; other site
1151116015782	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1151116015783	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1151116015784	TM-ABC transporter signature motif; other site
1151116015785	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1151116015786	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1151116015787	TM-ABC transporter signature motif; other site
1151116015788	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1151116015789	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
1151116015790	ligand binding site [chemical binding]; other site
1151116015791	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1151116015792	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116015793	DNA-binding site [nucleotide binding]; DNA binding site
1151116015794	FCD domain; Region: FCD; pfam07729
1151116015795	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1151116015796	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
1151116015797	metal binding site [ion binding]; metal-binding site
1151116015798	putative dimer interface [polypeptide binding]; other site
1151116015799	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1151116015800	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1151116015801	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1151116015802	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1151116015803	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1151116015804	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1151116015805	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1151116015806	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1151116015807	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1151116015808	Walker A/P-loop; other site
1151116015809	ATP binding site [chemical binding]; other site
1151116015810	Q-loop/lid; other site
1151116015811	ABC transporter signature motif; other site
1151116015812	Walker B; other site
1151116015813	D-loop; other site
1151116015814	H-loop/switch region; other site
1151116015815	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1151116015816	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1151116015817	Walker A/P-loop; other site
1151116015818	ATP binding site [chemical binding]; other site
1151116015819	Q-loop/lid; other site
1151116015820	ABC transporter signature motif; other site
1151116015821	Walker B; other site
1151116015822	D-loop; other site
1151116015823	H-loop/switch region; other site
1151116015824	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1151116015825	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1151116015826	HlyD family secretion protein; Region: HlyD_3; pfam13437
1151116015827	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1151116015828	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116015829	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1151116015830	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1151116015831	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1151116015832	dimer interface [polypeptide binding]; other site
1151116015833	active site
1151116015834	metal binding site [ion binding]; metal-binding site
1151116015835	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1151116015836	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
1151116015837	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1151116015838	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116015839	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1151116015840	substrate binding pocket [chemical binding]; other site
1151116015841	dimerization interface [polypeptide binding]; other site
1151116015842	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116015843	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116015844	active site
1151116015845	catalytic tetrad [active]
1151116015846	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1151116015847	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1151116015848	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1151116015849	putative active site [active]
1151116015850	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1151116015851	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1151116015852	putative active site [active]
1151116015853	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116015854	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116015855	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1151116015856	putative effector binding pocket; other site
1151116015857	putative dimerization interface [polypeptide binding]; other site
1151116015858	putative sporulation protein YtaF; Region: spore_YtaF; TIGR02840
1151116015859	Domain of unknown function DUF; Region: DUF204; pfam02659
1151116015860	Domain of unknown function DUF; Region: DUF204; pfam02659
1151116015861	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1151116015862	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1151116015863	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1151116015864	Protein of unknown function (DUF796); Region: DUF796; pfam05638
1151116015865	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
1151116015866	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1151116015867	type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359
1151116015868	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
1151116015869	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1151116015870	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1151116015871	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1151116015872	PAAR motif; Region: PAAR_motif; pfam05488
1151116015873	type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363
1151116015874	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1151116015875	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
1151116015876	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
1151116015877	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1151116015878	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
1151116015879	ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331
1151116015880	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1151116015881	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116015882	Walker A motif; other site
1151116015883	ATP binding site [chemical binding]; other site
1151116015884	Walker B motif; other site
1151116015885	arginine finger; other site
1151116015886	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116015887	Walker A motif; other site
1151116015888	ATP binding site [chemical binding]; other site
1151116015889	Walker B motif; other site
1151116015890	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1151116015891	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1151116015892	ImpA domain protein; Region: DUF3702; pfam12486
1151116015893	K+ potassium transporter; Region: K_trans; cl15781
1151116015894	potassium uptake protein; Region: kup; TIGR00794
1151116015895	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1151116015896	Beta-lactamase; Region: Beta-lactamase; pfam00144
1151116015897	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262
1151116015898	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1151116015899	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1151116015900	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1151116015901	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116015902	active site
1151116015903	motif I; other site
1151116015904	motif II; other site
1151116015905	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1151116015906	Glycine-zipper containing OmpA-like membrane domain; Region: Gly-zipper_OmpA; pfam13436
1151116015907	manganese transport regulator MntR; Provisional; Region: PRK11050
1151116015908	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1151116015909	DNA-binding site [nucleotide binding]; DNA binding site
1151116015910	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1151116015911	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1151116015912	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1151116015913	metal binding site [ion binding]; metal-binding site
1151116015914	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1151116015915	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1151116015916	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1151116015917	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116015918	ABC-ATPase subunit  interface; other site
1151116015919	dimer interface [polypeptide binding]; other site
1151116015920	putative PBP binding regions; other site
1151116015921	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1151116015922	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1151116015923	ABC-ATPase subunit  interface; other site
1151116015924	dimer interface [polypeptide binding]; other site
1151116015925	putative PBP binding regions; other site
1151116015926	tryptophan permease; Provisional; Region: PRK10483
1151116015927	aromatic amino acid transport protein; Region: araaP; TIGR00837
1151116015928	Pirin-related protein [General function prediction only]; Region: COG1741
1151116015929	Pirin; Region: Pirin; pfam02678
1151116015930	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1151116015931	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116015932	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1151116015933	H+ Antiporter protein; Region: 2A0121; TIGR00900
1151116015934	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116015935	putative substrate translocation pore; other site
1151116015936	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1151116015937	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1151116015938	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1151116015939	C factor cell-cell signaling protein; Provisional; Region: PRK09009
1151116015940	carbonyl reductase sniffer-like, classical (c) SDRs; Region: carb_red_sniffer_like_SDR_c; cd05325
1151116015941	NADP binding site [chemical binding]; other site
1151116015942	homodimer interface [polypeptide binding]; other site
1151116015943	active site
1151116015944	Protein of unknown function (DUF3750); Region: DUF3750; pfam12570
1151116015945	malate dehydrogenase; Provisional; Region: PRK13529
1151116015946	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1151116015947	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1151116015948	NAD(P) binding site [chemical binding]; other site
1151116015949	Predicted permeases [General function prediction only]; Region: COG0679
1151116015950	fumarate hydratase; Provisional; Region: PRK15389
1151116015951	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1151116015952	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1151116015953	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1151116015954	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1151116015955	transmembrane helices; other site
1151116015956	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1151116015957	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1151116015958	putative active site [active]
1151116015959	putative FMN binding site [chemical binding]; other site
1151116015960	putative substrate binding site [chemical binding]; other site
1151116015961	putative catalytic residue [active]
1151116015962	FMN-binding domain; Region: FMN_bind; cl01081
1151116015963	L-aspartate oxidase; Provisional; Region: PRK06175
1151116015964	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1151116015965	ApbE family; Region: ApbE; pfam02424
1151116015966	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1151116015967	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1151116015968	active site
1151116015969	phosphorylation site [posttranslational modification]
1151116015970	intermolecular recognition site; other site
1151116015971	dimerization interface [polypeptide binding]; other site
1151116015972	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1151116015973	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116015974	ATP binding site [chemical binding]; other site
1151116015975	Mg2+ binding site [ion binding]; other site
1151116015976	G-X-G motif; other site
1151116015977	Domain of unknown function (DUF3315); Region: DUF3315; cl02275
1151116015978	oxidoreductase; Provisional; Region: PRK06128
1151116015979	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1151116015980	NAD binding site [chemical binding]; other site
1151116015981	metal binding site [ion binding]; metal-binding site
1151116015982	active site
1151116015983	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1151116015984	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1151116015985	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1151116015986	putative active site [active]
1151116015987	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1151116015988	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1151116015989	N-terminal plug; other site
1151116015990	ligand-binding site [chemical binding]; other site
1151116015991	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1151116015992	intersubunit interface [polypeptide binding]; other site
1151116015993	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1151116015994	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116015995	putative substrate translocation pore; other site
1151116015996	POT family; Region: PTR2; cl17359
1151116015997	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1151116015998	ArsC family; Region: ArsC; pfam03960
1151116015999	catalytic residues [active]
1151116016000	arsenical pump membrane protein; Provisional; Region: PRK15445
1151116016001	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1151116016002	transmembrane helices; other site
1151116016003	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1151116016004	dimerization interface [polypeptide binding]; other site
1151116016005	putative DNA binding site [nucleotide binding]; other site
1151116016006	putative Zn2+ binding site [ion binding]; other site
1151116016007	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116016008	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116016009	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116016010	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116016011	Cupin; Region: Cupin_6; pfam12852
1151116016012	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1151116016013	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1151116016014	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1151116016015	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1151116016016	active site
1151116016017	catalytic tetrad [active]
1151116016018	Protein of unknown function (DUF3443); Region: DUF3443; pfam11925
1151116016019	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
1151116016020	putative trimer interface [polypeptide binding]; other site
1151116016021	putative active site [active]
1151116016022	putative substrate binding site [chemical binding]; other site
1151116016023	putative CoA binding site [chemical binding]; other site
1151116016024	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1151116016025	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116016026	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116016027	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1151116016028	putative effector binding pocket; other site
1151116016029	dimerization interface [polypeptide binding]; other site
1151116016030	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1151116016031	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1151116016032	putative NAD(P) binding site [chemical binding]; other site
1151116016033	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1151116016034	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1151116016035	Coenzyme A binding pocket [chemical binding]; other site
1151116016036	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1151116016037	nudix motif; other site
1151116016038	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1151116016039	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
1151116016040	dimer interface [polypeptide binding]; other site
1151116016041	ligand binding site [chemical binding]; other site
1151116016042	Colicin pore forming domain; Region: Colicin; pfam01024
1151116016043	Colicin immunity protein; Region: Colicin_im; pfam03857
1151116016044	multiple promoter invertase; Provisional; Region: mpi; PRK13413
1151116016045	Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient...; Region: SR_Res_par; cd03767
1151116016046	catalytic residues [active]
1151116016047	catalytic nucleophile [active]
1151116016048	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1151116016049	DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481
1151116016050	active site
1151116016051	AAA domain; Region: AAA_23; pfam13476
1151116016052	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1151116016053	Walker A/P-loop; other site
1151116016054	ATP binding site [chemical binding]; other site
1151116016055	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1151116016056	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1151116016057	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1151116016058	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1151116016059	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1151116016060	catalytic residues [active]
1151116016061	catalytic nucleophile [active]
1151116016062	Presynaptic Site I dimer interface [polypeptide binding]; other site
1151116016063	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1151116016064	Synaptic Flat tetramer interface [polypeptide binding]; other site
1151116016065	Synaptic Site I dimer interface [polypeptide binding]; other site
1151116016066	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1151116016067	DNA-binding interface [nucleotide binding]; DNA binding site
1151116016068	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1151116016069	Transposase; Region: HTH_Tnp_1; pfam01527
1151116016070	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1151116016071	HTH-like domain; Region: HTH_21; pfam13276
1151116016072	Integrase core domain; Region: rve; pfam00665
1151116016073	Integrase core domain; Region: rve_3; pfam13683
1151116016074	NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the...; Region: NifH; cd02040
1151116016075	nitrogenase iron protein; Region: nifH; TIGR01287
1151116016076	Nucleotide-binding sites [chemical binding]; other site
1151116016077	Walker A motif; other site
1151116016078	Switch I region of nucleotide binding site; other site
1151116016079	Fe4S4 binding sites [ion binding]; other site
1151116016080	Switch II region of nucleotide binding site; other site
1151116016081	Nitrogenase molybdenum-iron protein, alpha and beta chains [Energy production and conversion]; Region: NifD; COG2710
1151116016082	Nitrogenase_MoFe_alpha_II: Nitrogenase MoFe protein, beta subunit. A group of proteins similar to the alpha subunit of the MoFe protein of the molybdenum (Mo-) nitrogenase. The nitrogenase enzyme catalyzes the ATP-dependent reduction of dinitrogen to...; Region: Nitrogenase_MoFe_alpha; cd01976
1151116016083	MoFe protein alpha/beta subunit interactions; other site
1151116016084	Alpha subunit P cluster binding residues; other site
1151116016085	FeMoco binding residues [chemical binding]; other site
1151116016086	MoFe protein alpha subunit/Fe protein contacts; other site
1151116016087	MoFe protein dimer/ dimer interactions; other site
1151116016088	nitrogenase molybdenum-iron protein beta chain; Region: nifK; TIGR01286
1151116016089	Domain of unknown function (DUF3364); Region: DUF3364; pfam11844
1151116016090	Nitrogenase_MoFe_beta: Nitrogenase MoFe protein, beta subunit. The nitrogenase enzyme catalyzes the ATP-dependent reduction of dinitrogen to ammonia. The Molybdenum (Mo-) nitrogenase is the most widespread and best characterized of these systems; Region: Nitrogenase_MoFe_beta; cd01974
1151116016091	MoFe protein beta/alpha subunit interactions; other site
1151116016092	Beta subunit P cluster binding residues; other site
1151116016093	MoFe protein beta subunit/Fe protein contacts; other site
1151116016094	MoFe protein dimer/ dimer interactions; other site
1151116016095	NifT/FixU protein; Region: NifT; pfam06988
1151116016096	NifX belongs to a family of iron-molybdenum cluster-binding proteins that includes NifB,  and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  The protein...; Region: NifX; cd00853
1151116016097	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
1151116016098	nitrogenase molybdenum-iron cofactor biosynthesis protein NifE; Region: nifE; TIGR01283
1151116016099	Nitrogenase_nifN1: A subgroup of the NifN subunit of the NifEN complex: NifN forms an alpha2beta2 tetramer with NifE.  NifN and nifE are structurally homologous to nitrogenase MoFe protein beta and alpha subunits respectively.  NifEN participates in the...; Region: Nitrogenase_NifN_1; cd01966
1151116016100	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
1151116016101	NifX belongs to a family of iron-molybdenum cluster-binding proteins that includes NifB,  and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  The protein...; Region: NifX; cd00853
1151116016102	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
1151116016103	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1151116016104	trimerization site [polypeptide binding]; other site
1151116016105	active site
1151116016106	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1151116016107	NifU-like domain; Region: NifU; pfam01106
1151116016108	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1151116016109	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1151116016110	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1151116016111	catalytic residue [active]
1151116016112	homocitrate synthase NifV; Region: nifV_homocitr; TIGR02660
1151116016113	Streptomyces rubellomurinus FrbC and related proteins, catalytic TIM barrel domain; Region: DRE_TIM_NifV; cd07939
1151116016114	active site
1151116016115	catalytic residues [active]
1151116016116	metal binding site [ion binding]; metal-binding site
1151116016117	Nitrogen fixation protein NifW; Region: NifW; pfam03206
1151116016118	NifZ domain; Region: NifZ; pfam04319
1151116016119	nitrogen fixation protein NifM; Region: nifM_nitrog; TIGR02933
1151116016120	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1151116016121	nitrogen fixation negative regulator NifL; Region: nifL_nitrog; TIGR02938
1151116016122	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1151116016123	putative active site [active]
1151116016124	heme pocket [chemical binding]; other site
1151116016125	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1151116016126	ATP binding site [chemical binding]; other site
1151116016127	Mg2+ binding site [ion binding]; other site
1151116016128	G-X-G motif; other site
1151116016129	Nif-specific regulatory protein; Region: nifA; TIGR01817
1151116016130	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1151116016131	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1151116016132	Walker A motif; other site
1151116016133	ATP binding site [chemical binding]; other site
1151116016134	Walker B motif; other site
1151116016135	arginine finger; other site
1151116016136	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1151116016137	nitrogenase cofactor biosynthesis protein NifB; Region: nifB; TIGR01290
1151116016138	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1151116016139	FeS/SAM binding site; other site
1151116016140	NifB belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme as part of...; Region: NifB; cd00852
1151116016141	NifQ; Region: NifQ; pfam04891
1151116016142	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
1151116016143	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1151116016144	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
1151116016145	flavodoxin FldA; Validated; Region: PRK09267
1151116016146	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1151116016147	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1151116016148	dimer interface [polypeptide binding]; other site
1151116016149	PYR/PP interface [polypeptide binding]; other site
1151116016150	TPP binding site [chemical binding]; other site
1151116016151	substrate binding site [chemical binding]; other site
1151116016152	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1151116016153	Domain of unknown function; Region: EKR; pfam10371
1151116016154	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1151116016155	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1151116016156	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1151116016157	TPP-binding site [chemical binding]; other site
1151116016158	dimer interface [polypeptide binding]; other site
1151116016159	Cache domain; Region: Cache_1; pfam02743
1151116016160	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1151116016161	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1151116016162	metal binding site [ion binding]; metal-binding site
1151116016163	active site
1151116016164	I-site; other site
1151116016165	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1151116016166	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1151116016167	Cre recombinase, C-terminal catalytic domain. Cre-like recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The bacteriophage P1 Cre...; Region: INT_Cre; cd00799
1151116016168	DNA binding site [nucleotide binding]
1151116016169	dimer interface [polypeptide binding]; other site
1151116016170	active site
1151116016171	Int/Topo IB signature motif; other site
1151116016172	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1151116016173	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
1151116016174	Protein of unknown function (DUF1018); Region: DUF1018; cl01815
1151116016175	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1151116016176	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1151116016177	putative substrate binding site [chemical binding]; other site
1151116016178	putative ATP binding site [chemical binding]; other site
1151116016179	Glycosyl hydrolase family 32; Region: GH32_Aec43_like; cd08995
1151116016180	active site
1151116016181	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
1151116016182	potential frameshift: common BLAST hit: gi|365968802|ref|YP_004950363.1| sucrose-6-phosphate hydrolase
1151116016183	galactoside permease; Reviewed; Region: lacY; PRK09528
1151116016184	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116016185	putative substrate translocation pore; other site
1151116016186	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1151116016187	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1151116016188	DNA binding site [nucleotide binding]
1151116016189	domain linker motif; other site
1151116016190	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
1151116016191	putative dimerization interface [polypeptide binding]; other site
1151116016192	putative ligand binding site [chemical binding]; other site
1151116016193	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1151116016194	DNA helicase TraI; Region: TraI; pfam07057
1151116016195	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
1151116016196	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1151116016197	potential catalytic triad [active]
1151116016198	conserved cys residue [active]
1151116016199	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116016200	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116016201	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
1151116016202	putative effector binding pocket; other site
1151116016203	putative dimerization interface [polypeptide binding]; other site
1151116016204	Colicin immunity protein; Region: Colicin_im; pfam03857
1151116016205	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1151116016206	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1151116016207	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1151116016208	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1151116016209	catalytic residue [active]
1151116016210	TraM protein; Region: Tra_M; cl11621
1151116016211	TraA; Region: TraA; cl11503
1151116016212	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
1151116016213	TraE protein; Region: TraE; cl05060
1151116016214	conjugal transfer protein TraK; Provisional; Region: PRK13736; cl05878
1151116016215	TraK protein; Region: TraK; pfam06586
1151116016216	conjugal transfer pilus assembly protein TraB; Provisional; Region: PRK13729
1151116016217	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
1151116016218	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1151116016219	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1151116016220	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1151116016221	heterodimer interface [polypeptide binding]; other site
1151116016222	homodimer interface [polypeptide binding]; other site
1151116016223	conjugal transfer protein TraV; Provisional; Region: PRK13733
1151116016224	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
1151116016225	conjugal transfer ATP-binding protein TraC; Provisional; Region: PRK13721
1151116016226	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
1151116016227	Type-F conjugative transfer system protein (TrbI_Ftype); Region: TrbI_Ftype; pfam09677
1151116016228	Sex factor F TraW protein N terminal; Region: TraW_N; cl10149
1151116016229	conjugal transfer pilus assembly protein TraU; Provisional; Region: PRK13737
1151116016230	Type-F conjugative transfer system pilin assembly protein; Region: TrbC_Ftype; cl09883
1151116016231	conjugal transfer mating pair stabilization protein TraN; Reviewed; Region: PRK12355
1151116016232	conjugal pilus assembly protein TraF; Provisional; Region: PRK13703
1151116016233	F plasmid transfer operon protein; Region: TraF; pfam13728
1151116016234	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
1151116016235	conjugal transfer pilus assembly protein TraH; Provisional; Region: PRK13723
1151116016236	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
1151116016237	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
1151116016238	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
1151116016239	type IV conjugative transfer system coupling protein TraD; Region: TraD_Ftype; TIGR02759
1151116016240	F sex factor protein N terminal; Region: TraD_N; pfam12615
1151116016241	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1151116016242	Walker A motif; other site
1151116016243	ATP binding site [chemical binding]; other site
1151116016244	Walker B motif; other site
1151116016245	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
1151116016246	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK13709
1151116016247	AAA domain; Region: AAA_30; pfam13604
1151116016248	DNA helicase TraI; Region: TraI; pfam07057
1151116016249	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1151116016250	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1151116016251	catalytic residues [active]
1151116016252	Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170
1151116016253	PLD-like domain; Region: PLDc_2; pfam13091
1151116016254	putative active site [active]
1151116016255	catalytic site [active]
1151116016256	Abi-like protein; Region: Abi_2; pfam07751
1151116016257	3D domain; Region: 3D; cl01439
1151116016258	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1151116016259	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1151116016260	putative substrate translocation pore; other site
1151116016261	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1151116016262	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1151116016263	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1151116016264	dimerization interface [polypeptide binding]; other site