-- dump date 20140620_024309 -- class Genbank::CDS -- table cds_note -- id note YP_001976182.1 yhch00001 YP_001976183.1 yhch00002 YP_001976184.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001976185.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001976186.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001976187.1 3'-5' exonuclease of DNA polymerase III YP_001976188.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001976189.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_001976190.1 ypch00002 YP_001976192.1 ypch00003 YP_001976193.1 ypch00004 YP_001976194.1 negatively supercoils closed circular double-stranded DNA YP_001976195.1 ypch00005 YP_001976196.1 yhch00004 YP_001976197.1 ypch00006 YP_001976198.1 bifunctional ypch00007 YP_001976199.1 ypch00008 YP_001976200.1 yhch00005 YP_001976201.1 ypch00009 YP_001976202.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_001976203.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001976204.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001976205.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001976206.1 bifunctional folC YP_001976208.1 ypch00010 YP_001976209.1 yhch00006 YP_001976210.1 ypch00011 YP_001976211.1 yhch00007 YP_001976212.1 ypch00012 YP_001976213.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001976214.1 ypch00013 YP_001976215.1 ypch00014 YP_001976216.1 yhch00008 YP_001976219.1 yhch00009 YP_001976220.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001976221.1 ypch00015 YP_001976223.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001976224.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001976225.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001976226.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001976227.1 yhch00010 YP_001976228.1 yhch00011 YP_001976229.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001976230.1 yhch00012 YP_001976231.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001976232.1 heat shock protein involved in degradation of misfolded proteins YP_001976233.1 heat shock protein involved in degradation of misfolded proteins YP_001976234.1 yhch00013 YP_001976235.1 ypch00016 YP_001976236.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001976237.1 yhch00014 YP_001976238.1 yhch00015 YP_001976242.1 catalyzes the formation of L-proline from L-ornithine YP_001976243.1 yhch00016 YP_001976244.1 yhch00017 YP_001976245.1 ypch00017 YP_001976246.1 yhch00018 YP_001976247.1 ypch00018 YP_001976249.1 ypch00019 YP_001976250.1 yhch00019 YP_001976251.1 ypch00020 YP_001976252.1 ypch00021 YP_001976253.1 ypch00022 YP_001976254.1 yhch00020 YP_001976255.1 ypch00023 YP_001976256.1 ypch00024 YP_001976257.1 ypch00025 YP_001976258.1 yhch00021 YP_001976259.1 ypch00026 YP_001976260.1 ypch00027 YP_001976261.1 ypch00028 YP_001976262.1 ypch00029 YP_001976263.1 ypch00030 YP_001976264.1 ypch00031 YP_001976265.1 ypch00032 YP_001976266.1 ypch00033 YP_001976267.1 ypch00034 YP_001976269.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_001976270.1 yhch00022 YP_001976272.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001976273.1 ypch00035 YP_001976275.1 yhch00023 YP_001976276.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001976277.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001976278.1 yhch00024 YP_001976279.1 ypch00036 YP_001976280.1 yhch00025 YP_001976281.1 ypch00037; fusion protein: hypothetical conserved protein (RL2865) and adenylate cyclase (Smed_2780) protein YP_001976282.1 yhch00026 YP_001976283.1 yhch00027 YP_001976284.1 yhch00028 YP_001976285.1 yhch00029 YP_001976286.1 ypch00038 YP_001976287.1 ypch00039 YP_001976288.1 ypch00040 YP_001976289.1 yhch00030 YP_001976290.1 yhch00031 YP_001976291.1 yhch00032 YP_001976292.1 ypch00041 YP_001976293.1 ypch00042 YP_001976294.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001976295.1 ypch00044 YP_001976296.1 ypch00045 YP_001976297.1 ypch00046 YP_001976298.1 yhch00033 YP_001976299.1 ypch00047 YP_001976300.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001976301.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_001976302.1 catalyzes the degradation of arginine to citruline and ammonia YP_001976303.1 yhch00034 YP_001976306.1 yhch00035 YP_001976307.1 yhch00036 YP_001976308.1 ypch00048 YP_001976309.1 yhch00037 YP_001976310.1 ypch00049 YP_001976311.1 yhch00038 YP_001976312.1 yhch00039 YP_001976313.1 yhch00040 YP_001976314.1 yhch00041 YP_001976315.1 yhch00042 YP_001976317.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001976318.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001976319.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001976320.1 ypch00050 YP_001976322.1 yhch00043 YP_001976323.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001976324.1 ypch00051 YP_001976325.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001976326.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001976327.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001976328.1 yhch00044 YP_001976329.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001976330.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001976331.1 ypch00052 YP_001976332.1 ypch00053 YP_001976333.1 ypch00054 YP_001976334.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001976335.1 yhch00046 YP_001976336.1 yhch00047 YP_001976337.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001976338.1 yhch00048 YP_001976339.1 ypch00055 YP_001976340.1 ypch00056 YP_001976341.1 yhch00049 YP_001976342.1 ypch00057 YP_001976343.1 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001976344.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001976346.1 ypch00058 YP_001976347.1 ypch00059 YP_001976348.1 yhch00050 YP_001976349.1 ypch00060 YP_001976350.1 ypch00061 YP_001976351.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001976352.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001976353.1 yhch00051 YP_001976354.1 ypch00062 YP_001976355.1 yhch00052 YP_001976356.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001976357.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001976358.1 ypch00063 YP_001976359.1 yhch00053 YP_001976360.1 yhch00054 YP_001976362.1 ypch00064 YP_001976363.1 ypch00065 YP_001976364.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001976366.1 ypch00066 YP_001976367.1 ypch00067 YP_001976368.1 ypch00068 YP_001976369.1 ypch00069 YP_001976370.1 ypch00070 YP_001976371.1 yhch00055 YP_001976374.1 yhch00056 YP_001976375.1 ypch00071 YP_001976376.1 ypch00072 YP_001976377.1 ypch00073 YP_001976378.1 ypch00074 YP_001976379.1 ypch00075 YP_001976380.1 ypch00076 YP_001976381.1 ypch00077 YP_001976386.1 ypch00078 YP_001976387.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001976388.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001976389.1 ypch00079 YP_001976390.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001976391.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001976392.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001976393.1 ypch00080 YP_001976394.1 ypch00081 YP_001976395.1 ypch00082 YP_001976396.1 ypch00083 YP_001976397.1 ypch00084 YP_001976398.1 yhch00057 YP_001976399.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001976400.1 yhch00058 YP_001976401.1 yhch00059 YP_001976402.1 yhch00060 YP_001976403.1 yhch00061 YP_001976404.1 yhch00062 YP_001976405.1 ypch00085 YP_001976406.1 ypch00086 YP_001976407.1 ypch00087 YP_001976408.1 ypch00088 YP_001976409.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001976410.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001976411.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001976412.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001976413.1 yhch00063 YP_001976414.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001976415.1 catalyzes the formation of inosine from adenosine YP_001976416.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001976417.1 yhch00064 YP_001976418.1 yhch00065 YP_001976427.1 ypch00089 YP_001976429.1 ypch00090 YP_001976430.1 ypch00091 YP_001976431.1 ypch00092 YP_001976432.1 ypch00093 YP_001976433.1 ypch00094 YP_001976434.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001976435.1 ypch00095 YP_001976436.1 ypch00096 YP_001976437.1 ypch00097 YP_001976438.1 ypch00098 YP_001976439.1 yhch00066 YP_001976440.1 ypch00099 YP_001976441.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001976443.1 ypch00100 YP_001976444.1 ypch00101 YP_001976445.1 ypch00102 YP_001976446.1 yhch00067 YP_001976447.1 yhch00068 YP_001976448.1 yhch00069 YP_001976449.1 yhch00070 YP_001976450.1 ypch00103 YP_001976452.1 ypch00104 YP_001976453.1 yhch00071 YP_001976454.1 yhch00072 YP_001976455.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001976456.1 ypch00105 YP_001976457.1 ypch00106 YP_001976458.1 ypch00107 YP_001976459.1 ypch00108 YP_001976461.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001976462.1 ypch00109 YP_001976463.1 yhch00073 YP_001976464.1 yhch00074 YP_001976465.1 ypch00110 YP_001976466.1 ypch00111 YP_001976467.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001976468.1 yhch00075 YP_001976470.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001976471.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001976472.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001976473.1 yhch00076 YP_001976474.1 ypch00112 YP_001976475.1 ypch00113 YP_001976476.1 yhch00077 YP_001976477.1 yhch00078 YP_001976478.1 ypch00114 YP_001976479.1 ypch00115 YP_001976480.1 ypch00116 YP_001976481.1 yhch00079 YP_001976482.1 ypch00117 YP_001976483.1 yhch00080 YP_001976484.1 yhch00081 YP_001976485.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001976486.1 ypch00118 YP_001976487.1 ypch00119 YP_001976488.1 ypch00120 YP_001976489.1 ypch00121 YP_001976491.1 ypch00122 YP_001976492.1 yhch00082 YP_001976493.1 ypch00123 YP_001976494.1 ypch00124 YP_001976495.1 ypch00125 YP_001976496.1 ypch00126 YP_001976497.1 yhch00083 YP_001976498.1 yhch00084 YP_001976499.1 ypch00127 YP_001976500.1 ypch00128 YP_001976501.1 ypch00129 YP_001976502.1 ypch00130 YP_001976503.1 ypch00131 YP_001976504.1 yhch00085 YP_001976505.1 yhch00086 YP_001976506.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001976507.1 Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001976508.1 ypch00132 YP_001976509.1 yhch00087 YP_001976510.1 yhch00088 YP_001976511.1 yhch00089 YP_001976512.1 yhch00090 YP_001976513.1 yhch00091 YP_001976515.1 ypch00133 YP_001976516.1 yhch00092 YP_001976517.1 ypch00134 YP_001976518.1 ypch00135 YP_001976520.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001976521.1 yhch00093 YP_001976522.1 ypch00136 YP_001976523.1 yhch00094 YP_001976524.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001976525.1 ypch00137 YP_001976527.1 yhch00095 YP_001976528.1 binds the polymerase to DNA and acts as a sliding clamp YP_001976529.1 ypch00138 YP_001976530.1 yhch00096 YP_001976531.1 yhch00097 YP_001976532.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001976533.1 ypch00139 YP_001976534.1 yhch00098 YP_001976535.1 yhch00099 YP_001976537.1 ypch00140 YP_001976538.1 ypch00141 YP_001976539.1 ypch00142 YP_001976540.1 ypch00143 YP_001976541.1 catalyzes the formation of dUMP from dUTP YP_001976543.1 ypch00144 YP_001976544.1 ypch00145 YP_001976545.1 yhch00100 YP_001976546.1 ypch00146 YP_001976547.1 ypch00147 YP_001976548.1 ypch00148 YP_001976549.1 ypch00149 YP_001976550.1 ypch00150 YP_001976551.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001976552.1 ypch00151 YP_001976553.1 ypch00152 YP_001976554.1 ypch00153 YP_001976555.1 ypch00154 YP_001976556.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001976557.1 yhch00101 YP_001976558.1 yhch00102 YP_001976559.1 yhch00103 YP_001976560.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001976564.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001976565.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001976566.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001976567.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001976568.1 yhch00104 YP_001976569.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001976570.1 ypch00156 YP_001976571.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001976572.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001976573.1 ypch00158 YP_001976574.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001976575.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001976576.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001976579.1 yhch00105 YP_001976580.1 yhch00106 YP_001976581.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001976582.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001976583.1 ypch00160 YP_001976584.1 Transfers the fatty acyl group on membrane lipoproteins YP_001976585.1 ypch00161 YP_001976586.1 yhch00107 YP_001976588.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001976592.1 ypch00163 YP_001976594.1 ypch00164 YP_001976595.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001976596.1 ypch00165 YP_001976597.1 yhch00108 YP_001976599.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001976600.1 yhch00109 YP_001976601.1 This protein performs the mismatch recognition step during the DNA repair process YP_001976602.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001976603.1 ypch00166 YP_001976604.1 yhch00110 YP_001976605.1 ypch00167 YP_001976606.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001976608.1 ypch00168 YP_001976609.1 ypch00169 YP_001976610.1 yhch00111 YP_001976611.1 ypch00170 YP_001976612.1 yhch00112 YP_001976613.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001976615.1 yhch00113 YP_001976616.1 yhch00114 YP_001976617.1 ypch00171 YP_001976618.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001976619.1 ypch00172 YP_001976620.1 ypch00173 YP_001976622.1 ypch00174 YP_001976624.1 ypch00175 YP_001976625.1 ypch00176 YP_001976626.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001976627.1 ypch00177 YP_001976629.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001976630.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001976631.1 yhch00115 YP_001976632.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001976633.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001976634.1 yhch00116 YP_001976635.1 yhch00117 YP_001976636.1 ypch00178 YP_001976639.1 ypch00179 YP_001976641.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001976643.1 yhch00118 YP_001976644.1 ypch00180 YP_001976645.1 ypch00181 YP_001976646.1 yhch00119 YP_001976647.1 yhch00120 YP_001976648.1 ypch00182 YP_001976649.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001976650.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001976651.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001976652.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001976655.1 yhch00121 YP_001976656.1 yhch00122 YP_001976657.1 yhch00123 YP_001976658.1 yhch00124 YP_001976659.1 yhch00125 YP_001976660.1 yhch00126 YP_001976661.1 yhch00127 YP_001976662.1 yhch00128 YP_001976663.1 yhch00129 YP_001976664.1 yhch00130 YP_001976665.1 yhch00131 YP_001976666.1 yhch00132 YP_001976667.1 yhch00133 YP_001976668.1 yhch00134 YP_001976669.1 yhch00135 YP_001976670.1 yhch00136 YP_001976671.1 yhch00137 YP_001976672.1 yhch00138 YP_001976673.1 yhch00139 YP_001976674.1 yhch00140 YP_001976675.1 yhch00141 YP_001976676.1 yhch00142 YP_001976677.1 yhch00143 YP_001976678.1 yhch00144 YP_001976679.1 ypch00183 YP_001976680.1 yhch00145 YP_001976681.1 yhch00146 YP_001976682.1 yhch00147 YP_001976683.1 yhch00148 YP_001976684.1 yhch00149 YP_001976686.1 ypch00184 YP_001976687.1 yhch00150 YP_001976688.1 yhch00151 YP_001976689.1 ypch00185 YP_001976690.1 ypch00186 YP_001976691.1 yhch00152 YP_001976692.1 yhch00153 YP_001976693.1 yhch00154 YP_001976694.1 ypch00187 YP_001976695.1 ypch00188 YP_001976696.1 yhch00155 YP_001976697.1 yhch00156 YP_001976698.1 ypch00189 YP_001976699.1 yhch00157 YP_001976700.1 ypch00190 YP_001976701.1 ypch00191 YP_001976702.1 yhch00158 YP_001976703.1 ypch00192 YP_001976704.1 yhch00159 YP_001976711.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001976712.1 ypch00193 YP_001976713.1 ypch00194 YP_001976714.1 yhch00160 YP_001976715.1 ypch00195 YP_001976716.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001976719.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001976720.1 activates fatty acids by binding to coenzyme A YP_001976721.1 yhch00161 YP_001976724.1 ypch00196 YP_001976725.1 ypch00197 YP_001976726.1 ypch00198 YP_001976727.1 ypch00199 YP_001976728.1 yhch00162 YP_001976729.1 ypch00200 YP_001976731.1 ypch00201 YP_001976732.1 ypch00202 YP_001976733.1 ypch00203 YP_001976734.1 ypch00204 YP_001976736.1 ypch00205 YP_001976737.1 ypch00206 YP_001976738.1 ypch00207 YP_001976739.1 yhch00163 YP_001976740.1 yhch00164 YP_001976741.1 ypch00208 YP_001976742.1 ypch00209 YP_001976743.1 yhch00165 YP_001976744.1 yhch00166 YP_001976745.1 yhch00167 YP_001976746.1 yhch00168 YP_001976747.1 yhch00169 YP_001976748.1 ypch00210 YP_001976749.1 yhch00170 YP_001976750.1 ypch00211 YP_001976751.1 ypch00212 YP_001976753.1 yhch00171 YP_001976757.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001976760.1 yhch00172 YP_001976761.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001976762.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001976763.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001976764.1 yhch00173 YP_001976765.1 protein associated with Co2+ and Mg2+ efflux YP_001976766.1 catalyzes the conversion of O-succinylhomoserine and sulfide to homocysteine; second step in methionine biosynthesis YP_001976767.1 Catalyzes the deamination of dCTP to form dUTP YP_001976768.1 yhch00174 YP_001976769.1 ypch00213 YP_001976771.1 yhch00175 YP_001976772.1 ypch00214 YP_001976773.1 yhch00176 YP_001976774.1 yhch00177 YP_001976775.1 ypch00215 YP_001976776.1 ypch00216 YP_001976777.1 yhch00178 YP_001976778.1 yhch00179 YP_001976779.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001976781.1 yhch00180 YP_001976782.1 yhch00181 YP_001976783.1 ypch00217 YP_001976784.1 yhch00182 YP_001976785.1 yhch00183 YP_001976786.1 yhch00184 YP_001976787.1 ypch00218 YP_001976788.1 yhch00185 YP_001976790.1 ypch00219 YP_001976791.1 yhch00186 YP_001976792.1 ypch00220 YP_001976793.1 yhch00187 YP_001976794.1 ypch00221 YP_001976795.1 yhch00188 YP_001976796.1 ypch00222 YP_001976797.1 ypch00223 YP_001976798.1 ypch00224 YP_001976800.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001976803.1 ypch00225 YP_001976804.1 yhch00189 YP_001976805.1 yhch00190 YP_001976806.1 ypch00226 YP_001976807.1 ypch00227 YP_001976808.1 ypch00228 YP_001976809.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001976810.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001976812.1 ypch00229 YP_001976813.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_001976814.1 ypch00231 YP_001976816.1 yhch00191 YP_001976817.1 yhch00192 YP_001976818.1 yhch00193 YP_001976819.1 yhch00194 YP_001976820.1 yhch00195 YP_001976821.1 yhch00196 YP_001976822.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001976823.1 yhch00197 YP_001976824.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001976825.1 yhch00198 YP_001976826.1 ypch00232 YP_001976827.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001976828.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001976829.1 yhch00199 YP_001976830.1 yhch00200 YP_001976831.1 yhch00201 YP_001976832.1 ypch00233 YP_001976833.1 yhch00202 YP_001976834.1 ypch00234 YP_001976835.1 ypch00235 YP_001976836.1 yhch00203 YP_001976837.1 yhch00204 YP_001976838.1 ypch00236 YP_001976839.1 ypch00237 YP_001976840.1 yhch00205 YP_001976841.1 ypch00238 YP_001976842.1 yhch00206 YP_001976843.1 ypch00239 YP_001976844.1 ypch00240 YP_001976845.1 ypch00241 YP_001976852.1 ypch00242 YP_001976853.1 ypch00243 YP_001976857.1 ypch00244 YP_001976858.1 ypch00245 YP_001976859.1 ypch00246 YP_001976860.1 ypch00247 YP_001976861.1 yhch00207 YP_001976862.1 yhch00208 YP_001976863.1 ypch00248 YP_001976864.1 ypch00249 YP_001976865.1 ypch00250 YP_001976866.1 ypch00251 YP_001976867.1 ypch00252 YP_001976868.1 ypch00253 YP_001976869.1 ypch00254 YP_001976870.1 ypch00255 YP_001976871.1 ypch00256 YP_001976872.1 ypch00257 YP_001976873.1 ypch00258 YP_001976874.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001976875.1 yhch00209 YP_001976876.1 ypch00259 YP_001976877.1 yhch00210 YP_001976878.1 yhch00211 YP_001976879.1 yhch00212 YP_001976886.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001976888.1 catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors YP_001976889.1 yhch00213 YP_001976890.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001976891.1 ypch00260 YP_001976892.1 ypch00261 YP_001976893.1 yhch00214 YP_001976894.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001976895.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001976898.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001976899.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001976900.1 involved in type III protein export during flagellum assembly YP_001976901.1 yhch00215 YP_001976902.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella YP_001976903.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001976904.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001976905.1 makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella YP_001976906.1 required for the assembly of the flagellar basal body P-ring; Bradyrhizobium japonicum has two types of flagella, a single thick flagella and a few thin flagella; the protein in this cluster is associated with the thin flagella YP_001976907.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001976908.1 ypch00262 YP_001976909.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001976911.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001976912.1 yhch00216 YP_001976913.1 yhch00217 YP_001976918.1 yhch00218 YP_001976919.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001976920.1 a periplasmic protein that interacts with and stabilizes MotB; in Rhizobium, interactions between MotB and MotC at the periplasmic surface of the motor control the energy flux or the energy coupling that drives flagellar rotation YP_001976922.1 ypch00263 YP_001976923.1 ypch00264 YP_001976924.1 the hook connects flagellar basal body to the flagellar filament YP_001976925.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001976926.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella YP_001976927.1 acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001976928.1 post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001976929.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella YP_001976930.1 FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum YP_001976931.1 membrane protein involved in the flagellar export apparatus YP_001976932.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001976933.1 yhch00219 YP_001976934.1 yhch00220 YP_001976935.1 yhch00221 YP_001976936.1 yhch00222 YP_001976938.1 ypch00265 YP_001976939.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001976941.1 yhch00223 YP_001976947.1 yhch00224 YP_001976948.1 yhch00225 YP_001976949.1 ypch00266 YP_001976950.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001976952.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001976955.1 yhch00226 YP_001976956.1 yhch00227 YP_001976959.1 yhch00228 YP_001976960.1 ypch00267 YP_001976961.1 yhch00229 YP_001976963.1 ypch00268 YP_001976968.1 yhch00230 YP_001976969.1 yhch00231 YP_001976970.1 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase YP_001976971.1 ypch00269 YP_001976972.1 yhch00232 YP_001976973.1 ypch00270 YP_001976974.1 yhch00234 YP_001976975.1 yhch00235 YP_001976976.1 ypch00271 YP_001976977.1 ypch00272 YP_001976979.1 rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons YP_001976984.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001976986.1 ypch00273 YP_001976987.1 ypch00274 YP_001976988.1 ypch00275 YP_001976989.1 yhch00236 YP_001976991.1 yhch00237 YP_001976992.1 ypch00276 YP_001976993.1 ypch00277 YP_001976994.1 yhch00238 YP_001976995.1 ypch00278 YP_001976996.1 ypch00279 YP_001976997.1 ypch00280 YP_001976998.1 ypch00281 YP_001976999.1 ypch00282 YP_001977000.1 ypch00283 YP_001977001.1 yhch00239 YP_001977002.1 ypch00284 YP_001977003.1 ypch00285 YP_001977004.1 ypch00286 YP_001977005.1 yhch00240 YP_001977006.1 yhch00241 YP_001977007.1 yhch00242 YP_001977008.1 yhch00243 YP_001977009.1 ypch00287; fusion protein: glycosyltransferase (Rleg2DRAFT_5721) and acetyltransferase (AmucDRAFT_1456) YP_001977010.1 yhch00244 YP_001977011.1 yhch00245 YP_001977012.1 yhch00246 YP_001977013.1 ypch00288 YP_001977015.1 ypch00289 YP_001977016.1 ypch00290 YP_001977017.1 yhch00247 YP_001977018.1 yhch00248 YP_001977019.1 yhch00249 YP_001977020.1 yhch00250 YP_001977021.1 yhch00251 YP_001977022.1 yhch00252 YP_001977023.1 yhch00253 YP_001977024.1 yhch00254 YP_001977025.1 yhch00255 YP_001977026.1 yhch00257 YP_001977027.1 yhch00258 YP_001977028.1 yhch00259 YP_001977029.1 ypch00291 YP_001977030.1 ypch00292 YP_001977031.1 ypch00293 YP_001977032.1 yhch00260 YP_001977033.1 yhch00261 YP_001977034.1 ypch00294 YP_001977035.1 yhch00262 YP_001977036.1 yhch00263 YP_001977039.1 ypch00295 YP_001977040.1 ypch00296 YP_001977041.1 ypch00297 YP_001977042.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001977043.1 yhch00264 YP_001977044.1 ypch00298 YP_001977045.1 ypch00299 YP_001977046.1 yhch00265 YP_001977047.1 ypch00300 YP_001977048.1 ypch00301 YP_001977049.1 yhch00266 YP_001977050.1 yhch00267 YP_001977052.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001977053.1 ypch00302 YP_001977054.1 ypch00303 YP_001977055.1 ypch00304 YP_001977059.1 yhch00269 YP_001977061.1 yhch00270 YP_001977062.1 yhch00271 YP_001977064.1 yhch00272 YP_001977065.1 ypch00305 YP_001977066.1 ypch00306 YP_001977067.1 yhch00273 YP_001977068.1 yhch00274 YP_001977069.1 yhch00275 YP_001977070.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001977071.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001977072.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001977073.1 yhch00276 YP_001977075.1 yhch00277 YP_001977076.1 yhch00278 YP_001977077.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_001977078.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001977079.1 ypch00307 YP_001977080.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001977081.1 ypch00308 YP_001977082.1 yhch00279 YP_001977083.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme YP_001977084.1 yhch00280 YP_001977086.1 ypch00309 YP_001977087.1 ypch00310 YP_001977088.1 ypch00311 YP_001977089.1 yhch00281 YP_001977090.1 ypch00312 YP_001977093.1 ypch00313 YP_001977094.1 yhch00282 YP_001977095.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001977096.1 ypch00314 YP_001977097.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001977098.1 yhch00283 YP_001977099.1 yhch00284 YP_001977100.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001977101.1 ypch00315 YP_001977102.1 ypch00316 YP_001977103.1 yhch00285 YP_001977104.1 ypch00317 YP_001977105.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001977108.1 ypch00318 YP_001977109.1 yhch00286 YP_001977110.1 ypch00319 YP_001977111.1 yhch00287 YP_001977112.1 yhch00288 YP_001977115.1 ypch00320 YP_001977117.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001977118.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001977119.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel. YP_001977120.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001977121.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001977122.1 ypch00321 YP_001977123.1 ypch00322 YP_001977124.1 yhch00289 YP_001977126.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001977127.1 yhch00290 YP_001977129.1 yhch00291 YP_001977130.1 ypch00323 YP_001977133.1 yhch00292 YP_001977134.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001977135.1 yhch00293 YP_001977136.1 yhch00294 YP_001977137.1 yhch00295 YP_001977139.1 yhch00296 YP_001977140.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001977141.1 yhch00297 YP_001977142.1 yhch00298 YP_001977143.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001977144.1 ypch00324 YP_001977146.1 ypch00325 YP_001977147.1 ypch00326 YP_001977148.1 yhch00299 YP_001977149.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin YP_001977150.1 yhch00300 YP_001977151.1 yhch00301 YP_001977152.1 ypch00327 YP_001977153.1 ypch00328 YP_001977154.1 yhch00302 YP_001977155.1 yhch00303 YP_001977156.1 ypch00329 YP_001977157.1 yhch00304 YP_001977158.1 yhch00305 YP_001977159.1 ypch00330 YP_001977160.1 ypch00331 YP_001977161.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001977162.1 yhch00306 YP_001977163.1 ypch00333 YP_001977164.1 ypch00334 YP_001977168.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001977169.1 yhch00307 YP_001977170.1 yhch00308 YP_001977171.1 ypch00335 YP_001977172.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001977173.1 ypch00336 YP_001977174.1 ypch00337 YP_001977177.1 catalyzes the formation of malonyl-CoA from malonate and CoA YP_001977179.1 ypch00338 YP_001977180.1 ypch00339 YP_001977181.1 ypch00340 YP_001977182.1 ypch00341 YP_001977183.1 yhch00309 YP_001977184.1 yhch00310 YP_001977185.1 N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid YP_001977186.1 ypch00342 YP_001977187.1 yhch00311 YP_001977189.1 ypch00343 YP_001977190.1 ypch00344 YP_001977191.1 yhch00312 YP_001977192.1 yhch00313 YP_001977194.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001977195.1 yhch00314 YP_001977196.1 yhch00315 YP_001977198.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001977200.1 yhch00316 YP_001977201.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001977202.1 ypch00345 YP_001977204.1 yhch00317 YP_001977206.1 ypch00346 YP_001977207.1 ypch00347 YP_001977209.1 yhch00318 YP_001977212.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001977213.1 yhch00319 YP_001977214.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001977216.1 ypch00348 YP_001977217.1 yhch00320 YP_001977218.1 ypch00349 YP_001977219.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001977220.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_001977221.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001977222.1 yhch00321 YP_001977223.1 yhch00322 YP_001977224.1 ypch00350 YP_001977225.1 yhch00323 YP_001977226.1 ypch00351 YP_001977227.1 yhch00324 YP_001977228.1 yhch00325 YP_001977229.1 ypch00352 YP_001977230.1 ypch00353 YP_001977231.1 ypch00354 YP_001977232.1 yhch00326 YP_001977233.1 yhch00327 YP_001977234.1 ypch00355 YP_001977236.1 ypch00356 YP_001977237.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001977238.1 yhch00328 YP_001977239.1 yhch00329 YP_001977240.1 ypch00357 YP_001977241.1 yhch00330 YP_001977242.1 yhch00331 YP_001977243.1 yhch00332 YP_001977244.1 ypch00358 YP_001977245.1 yhch00333 YP_001977246.1 ypch00359 YP_001977248.1 yhch00334 YP_001977249.1 ypch00360 YP_001977251.1 yhch00335 YP_001977252.1 yhch00336 YP_001977253.1 yhch00337 YP_001977254.1 yhch00338 YP_001977255.1 yhch00339 YP_001977256.1 ypch00361 YP_001977258.1 yhch00340 YP_001977259.1 ypch00362 YP_001977260.1 yhch00341 YP_001977261.1 ypch00363 YP_001977262.1 yhch00342 YP_001977263.1 yhch00343 YP_001977264.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001977265.1 yhch00344 YP_001977266.1 yhch00345 YP_001977267.1 yhch00346 YP_001977268.1 yhch00347 YP_001977269.1 yhch00348 YP_001977270.1 yhch00349 YP_001977271.1 yhch00350 YP_001977272.1 yhch00351 YP_001977273.1 ypch00364 YP_001977274.1 ypch00365 YP_001977275.1 yhch00352 YP_001977276.1 ypch00367 YP_001977277.1 yhch00353 YP_001977278.1 yhch00354 YP_001977279.1 ypch00368 YP_001977280.1 ypch00369 YP_001977281.1 yhch00355 YP_001977282.1 Synthesizes thioester adducts of fatty acids enzymatically to the phosphopantetheine group of acyl carrier protein YP_001977283.1 yhch00356 YP_001977285.1 yhch00357 YP_001977286.1 ypch00370 YP_001977287.1 yhch00358 YP_001977288.1 yhch00359 YP_001977289.1 yhch00360 YP_001977290.1 yhch00361 YP_001977291.1 yhch00362 YP_001977292.1 yhch00363 YP_001977293.1 yhch00364 YP_001977294.1 yhch00365 YP_001977295.1 yhch00366 YP_001977296.1 yhch00367 YP_001977297.1 yhch00368 YP_001977298.1 yhch00369 YP_001977299.1 yhch00370 YP_001977300.1 yhch00371 YP_001977301.1 yhch00372 YP_001977302.1 yhch00373 YP_001977303.1 ypch00372 YP_001977304.1 ypch00373 YP_001977305.1 ypch00374 YP_001977306.1 ypch00375 YP_001977307.1 ypch00376 YP_001977308.1 yhch00374 YP_001977309.1 yhch00375 YP_001977310.1 yhch00376 YP_001977311.1 ypch00377 YP_001977312.1 ypch00378 YP_001977313.1 yhch00377 YP_001977314.1 yhch00378 YP_001977315.1 yhch00379 YP_001977316.1 yhch00380 YP_001977317.1 ypch00379 YP_001977318.1 ypch00380 YP_001977319.1 yhch00381 YP_001977320.1 yhch00382 YP_001977321.1 ypch00381 YP_001977322.1 ypch00382 YP_001977323.1 yhch00383 YP_001977324.1 ypch00383 YP_001977325.1 ypch00384 YP_001977326.1 yhch00384 YP_001977327.1 yhch00385 YP_001977328.1 yhch00386 YP_001977329.1 yhch00387 YP_001977330.1 yhch00388 YP_001977331.1 yhch00389 YP_001977332.1 yhch00390 YP_001977333.1 ypch00385 YP_001977334.1 ypch00386 YP_001977335.1 yhch00391 YP_001977336.1 yhch00392 YP_001977337.1 yhch00393 YP_001977338.1 yhch00394 YP_001977339.1 ypch00387 YP_001977341.1 yhch00395 YP_001977342.1 yhch00396 YP_001977343.1 ypch00388 YP_001977344.1 yhch00397 YP_001977345.1 ypch00389 YP_001977346.1 yhch00398 YP_001977347.1 ypch00390 YP_001977348.1 yhch00399 YP_001977349.1 yhch00400 YP_001977350.1 yhch00401 YP_001977351.1 yhch00402 YP_001977352.1 yhch00403 YP_001977353.1 yhch00404 YP_001977354.1 yhch00405 YP_001977356.1 yhch00406 YP_001977357.1 ypch00391 YP_001977358.1 ypch00392 YP_001977359.1 yhch00407 YP_001977361.1 ypch00393 YP_001977362.1 yhch00408 YP_001977363.1 yhch00409 YP_001977364.1 ypch00394 YP_001977365.1 yhch00410 YP_001977366.1 ypch00395 YP_001977367.1 yhch00411 YP_001977368.1 yhch00412 YP_001977369.1 yhch00413 YP_001977370.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001977371.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001977373.1 ypch00396 YP_001977374.1 yhch00414 YP_001977375.1 yhch00415 YP_001977376.1 yhch00416 YP_001977377.1 ypch00397 YP_001977378.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001977379.1 catalyzes the formation of betaine from betaine aldehyde YP_001977380.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001977381.1 yhch00417 YP_001977382.1 yhch00418 YP_001977383.1 ypch00398 YP_001977384.1 ypch00399 YP_001977385.1 ypch00400 YP_001977386.1 ypch00401 YP_001977387.1 ypch00402 YP_001977388.1 ypch00403 YP_001977390.1 ypch00404 YP_001977391.1 yhch00419 YP_001977393.1 ypch00405 YP_001977394.1 yhch00420 YP_001977395.1 yhch00421 YP_001977396.1 yhch00422 YP_001977397.1 ypch00406 YP_001977399.1 yhch00423 YP_001977400.1 yhch00424 YP_001977401.1 ypch00407 YP_001977402.1 yhch00425 YP_001977403.1 ypch00408 YP_001977404.1 ypch00409 YP_001977406.1 ypch00410 YP_001977407.1 ypch00411 YP_001977408.1 ypch00412 YP_001977409.1 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA YP_001977410.1 ypch00414 YP_001977411.1 yhch00426 YP_001977412.1 yhch00427 YP_001977413.1 yhch00428 YP_001977414.1 yhch00429 YP_001977416.1 ypch00415 YP_001977417.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001977418.1 yhch00430 YP_001977419.1 ypch00416 YP_001977420.1 ypch00417 YP_001977421.1 ypch00418 YP_001977422.1 yhch00431 YP_001977423.1 yhch00432 YP_001977424.1 ypch00419 YP_001977425.1 ypch00420 YP_001977426.1 ypch00421 YP_001977427.1 yhch00433 YP_001977428.1 ypch00422 YP_001977429.1 yhch00434 YP_001977430.1 ypch00423 YP_001977431.1 yhch00435 YP_001977432.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001977433.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_001977435.1 yhch00436 YP_001977436.1 yhch00437 YP_001977437.1 ypch00424 YP_001977438.1 ypch00425 YP_001977439.1 ypch00426 YP_001977441.1 yhch00438 YP_001977442.1 ypch00427 YP_001977443.1 ypch00428 YP_001977444.1 ypch00429 YP_001977445.1 ypch00430 YP_001977446.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001977447.1 ypch00432 YP_001977448.1 ypch00433 YP_001977449.1 ypch00434 YP_001977450.1 yhch00439 YP_001977451.1 yhch00440 YP_001977452.1 ypch00435 YP_001977453.1 yhch00441 YP_001977455.1 ypch00436 YP_001977456.1 ypch00437 YP_001977457.1 ypch00438 YP_001977458.1 ypch00439 YP_001977459.1 ypch00440 YP_001977460.1 ypch00441 YP_001977461.1 ypch00442 YP_001977464.1 ypch00443 YP_001977465.1 yhch00442 YP_001977466.1 ypch00444 YP_001977469.1 yhch00443 YP_001977470.1 ypch00445 YP_001977471.1 yhch00444 YP_001977473.1 yhch00445 YP_001977474.1 ypch00446 YP_001977475.1 ypch00447 YP_001977476.1 ypch00448 YP_001977477.1 yhch00446 YP_001977478.1 ypch00449 YP_001977479.1 ypch00450 YP_001977480.1 ypch00451 YP_001977481.1 ypch00452 YP_001977482.1 yhch00447 YP_001977485.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_001977486.1 yhch00448 YP_001977487.1 ypch00453 YP_001977488.1 ypch00454 YP_001977489.1 yhch00449 YP_001977490.1 ypch00455 YP_001977491.1 ypch00456 YP_001977492.1 yhch00450 YP_001977493.1 yhch00451 YP_001977494.1 yhch00452 YP_001977495.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001977496.1 yhch00453 YP_001977497.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_001977498.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport YP_001977499.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001977500.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport YP_001977501.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001977502.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001977503.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_001977505.1 ypch00457 YP_001977506.1 yhch00454 YP_001977507.1 ypch00458 YP_001977508.1 ypch00459 YP_001977509.1 ypch00460 YP_001977510.1 yhch00455 YP_001977511.1 yhch00456 YP_001977512.1 yhch00457 YP_001977513.1 yhch00458 YP_001977514.1 yhch00459 YP_001977515.1 yhch00460 YP_001977517.1 yhch00461 YP_001977518.1 ypch00461 YP_001977519.1 ypch00463 YP_001977520.1 yhch00462 YP_001977521.1 yhch00463 YP_001977522.1 yhch00464 YP_001977523.1 yhch00465 YP_001977524.1 ypch00464 YP_001977525.1 ypch00465 YP_001977526.1 ypch00466 YP_001977527.1 yhch00466 YP_001977530.1 ypch00467 YP_001977531.1 yhch00467 YP_001977532.1 ypch00468 YP_001977533.1 yhch00468 YP_001977534.1 yhch00469 YP_001977535.1 yhch00470 YP_001977536.1 ypch00469 YP_001977537.1 yhch00471 YP_001977538.1 yhch00472 YP_001977543.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001977549.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001977550.1 ypch00470 YP_001977552.1 yhch00473 YP_001977553.1 ypch00471 YP_001977554.1 yhch00474 YP_001977555.1 yhch00475 YP_001977556.1 ypch00472 YP_001977558.1 ypch00473 YP_001977559.1 ypch00474 YP_001977560.1 ypch00475 YP_001977561.1 ypch00476 YP_001977563.1 yhch00476 YP_001977564.1 ypch00477 YP_001977565.1 ypch00478 YP_001977567.1 ypch00479 YP_001977568.1 yhch00477 YP_001977569.1 ypch00480 YP_001977570.1 ypch00481 YP_001977572.1 yhch00478 YP_001977573.1 ypch00482 YP_001977574.1 ypch00483 YP_001977575.1 ypch00484 YP_001977576.1 ypch00485 YP_001977577.1 yhch00479 YP_001977578.1 ypch00486 YP_001977579.1 yhch00480 YP_001977580.1 yhch00481 YP_001977581.1 yhch00482 YP_001977582.1 yhch00483 YP_001977583.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001977584.1 yhch00484 YP_001977585.1 yhch00485 YP_001977586.1 yhch00486 YP_001977587.1 catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate YP_001977588.1 yhch00487 YP_001977589.1 yhch00488 YP_001977590.1 yhch00489 YP_001977591.1 ypch00487 YP_001977592.1 yhch00490 YP_001977593.1 yhch00491 YP_001977594.1 yhch00492 YP_001977595.1 ypch00488 YP_001977600.1 ypch00489 YP_001977601.1 ypch00490 YP_001977602.1 ypch00491 YP_001977604.1 ypch00492 YP_001977605.1 ypch00493 YP_001977606.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001977607.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001977608.1 yhch00493 YP_001977609.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001977611.1 yhch00494 YP_001977612.1 yhch00495 YP_001977613.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001977615.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001977616.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001977617.1 ypch00494 YP_001977618.1 ypch00495 YP_001977619.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001977620.1 ypch00496 YP_001977621.1 ypch00497 YP_001977622.1 ypch00498 YP_001977623.1 ypch00499 YP_001977624.1 yhch00496 YP_001977626.1 ypch00500 YP_001977627.1 yhch00497 YP_001977628.1 ypch00501 YP_001977629.1 ypch00502 YP_001977630.1 yhch00498 YP_001977631.1 yhch00499 YP_001977632.1 yhch00500 YP_001977633.1 ypch00503 YP_001977634.1 yhch00501 YP_001977635.1 yhch00502 YP_001977637.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001977638.1 ypch00504 YP_001977639.1 ypch00505 YP_001977640.1 yhch00503 YP_001977641.1 ypch00506 YP_001977642.1 ypch00508 YP_001977643.1 yhch00504 YP_001977644.1 ypch00509 YP_001977647.1 ypch00510 YP_001977648.1 ypch00511 YP_001977649.1 ypch00512 YP_001977650.1 yhch00505 YP_001977651.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001977652.1 yhch00506 YP_001977653.1 ypch00513 YP_001977654.1 ypch00514 YP_001977655.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001977657.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001977658.1 ypch00515 YP_001977660.1 unwinds double stranded DNA YP_001977661.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001977662.1 yhch00507 YP_001977663.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001977664.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001977665.1 ypch00516 YP_001977667.1 catalyzes the formation of 3-hydroxyacyl-ACP from 3-keto-acyl-ACP; in the rhizobia this protein interacts with NodF to allow for the synthesis of highly polyunsaturated fatty acids necessary for nodulation YP_001977668.1 carries the fatty acid chain in fatty acid biosynthesis YP_001977669.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001977671.1 yhch00508 YP_001977672.1 Essential for recycling GMP and indirectly, cGMP YP_001977673.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001977674.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001977675.1 ypch00517 YP_001977677.1 ypch00518 YP_001977678.1 ypch00519 YP_001977679.1 ypch00520 YP_001977680.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001977681.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001977683.1 ypch00522 YP_001977684.1 ypch00523 YP_001977685.1 yhch00509 YP_001977686.1 ypch00524 YP_001977687.1 ypch00525 YP_001977688.1 ypch00526 YP_001977689.1 ypch00527 YP_001977690.1 ypch00528 YP_001977691.1 ypch00529 YP_001977692.1 ypch00530 YP_001977693.1 ypch00531 YP_001977694.1 yhch00510 YP_001977696.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001977697.1 yhch00511 YP_001977698.1 yhch00512 YP_001977699.1 ypch00532 YP_001977703.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001977704.1 ypch00533 YP_001977707.1 yhch00513 YP_001977708.1 ypch00534 YP_001977711.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001977712.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001977713.1 ypch00535 YP_001977714.1 yhch00514 YP_001977715.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001977717.1 yhch00515 YP_001977720.1 ypch00536 YP_001977721.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001977722.1 yhch00516 YP_001977723.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001977724.1 yhch00517 YP_001977725.1 ypch00537 YP_001977726.1 ypch00538 YP_001977727.1 ypch00539 YP_001977728.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001977729.1 yhch00518 YP_001977730.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001977731.1 yhch00519 YP_001977732.1 ypch00540 YP_001977733.1 ypch00541 YP_001977734.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001977735.1 yhch00520 YP_001977737.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001977742.1 yhch00521 YP_001977743.1 ypch00542 YP_001977744.1 ypch00543 YP_001977745.1 ypch00544 YP_001977746.1 ypch00545 YP_001977747.1 ypch00546 YP_001977748.1 ypch00547 YP_001977749.1 yhch00522 YP_001977750.1 yhch00523 YP_001977751.1 yhch00524 YP_001977752.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001977753.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001977754.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_001977755.1 ypch00548 YP_001977756.1 yhch00525 YP_001977757.1 yhch00526 YP_001977758.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001977759.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001977760.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001977761.1 ypch00549 YP_001977762.1 ypch00550 YP_001977763.1 ypch00551 YP_001977764.1 yhch00527 YP_001977765.1 yhch00528 YP_001977769.1 yhch00529 YP_001977770.1 ypch00552 YP_001977771.1 ypch00553 YP_001977772.1 yhch00530 YP_001977773.1 yhch00531 YP_001977774.1 yhch00532 YP_001977775.1 yhch00533 YP_001977776.1 ypch00554 YP_001977777.1 yhch00534 YP_001977778.1 ypch00555 YP_001977779.1 ypch00556 YP_001977780.1 ypch00557 YP_001977781.1 ypch00558 YP_001977782.1 yhch00535 YP_001977783.1 ypch00559 YP_001977784.1 ypch00560 YP_001977785.1 ypch00561 YP_001977787.1 yhch00536 YP_001977788.1 yhch00537 YP_001977789.1 ypch00562 YP_001977790.1 yhch00538 YP_001977791.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_001977792.1 catalyzes the formation of putrescine from agmatine YP_001977793.1 forms a direct contact with the tRNA during translation YP_001977794.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001977795.1 ypch00563 YP_001977796.1 yhch00539 YP_001977797.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001977798.1 ypch00565 YP_001977799.1 yhch00540 YP_001977800.1 yhch00541 YP_001977801.1 ypch00566 YP_001977802.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol YP_001977803.1 yhch00542 YP_001977804.1 ypch00568 YP_001977805.1 yhch00543 YP_001977806.1 yhch00544 YP_001977807.1 ypch00569 YP_001977808.1 yhch00545 YP_001977809.1 ypch00570 YP_001977810.1 yhch00546 YP_001977811.1 ypch00571 YP_001977812.1 ypch00572 YP_001977813.1 ypch00573 YP_001977814.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001977815.1 binds and unfolds substrates as part of the ClpXP protease YP_001977818.1 ypch00574 YP_001977819.1 yhch00547 YP_001977820.1 ypch00575 YP_001977821.1 yhch00548 YP_001977822.1 yhch00549 YP_001977823.1 yhch00550 YP_001977825.1 yhch00551 YP_001977826.1 yhch00552 YP_001977827.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977828.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001977829.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977830.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977831.1 yhch00553 YP_001977832.1 catalyzes the transfer of electrons from NADH to ubiquinone YP_001977833.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001977834.1 ypch00576 YP_001977835.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977836.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977837.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977838.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977839.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977840.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001977841.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977842.1 Catalyzes the transfer of electrons from NADH to quinone YP_001977844.1 ypch00577 YP_001977845.1 ypch00578 YP_001977846.1 yhch00554 YP_001977847.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001977848.1 ypch00579 YP_001977849.1 ypch00580 YP_001977850.1 yhch00555 YP_001977851.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001977852.1 yhch00556 YP_001977853.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001977854.1 ypch00581 YP_001977855.1 yhch00557 YP_001977856.1 yhch00558 YP_001977858.1 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP YP_001977859.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001977860.1 ypch00582 YP_001977861.1 yhch00559 YP_001977863.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001977865.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001977866.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001977867.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001977869.1 ypch00584 YP_001977870.1 yhch00561 YP_001977873.1 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA YP_001977874.1 yhch00562 YP_001977875.1 yhch00563 YP_001977876.1 catalyzes the phosphorylation of NAD to NADP YP_001977877.1 yhch00564 YP_001977878.1 yhch00565 YP_001977879.1 yhch00566 YP_001977881.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001977882.1 ypch00586 YP_001977883.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001977884.1 Modulates Rho-dependent transcription termination YP_001977885.1 binds directly to 23S ribosomal RNA YP_001977886.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001977887.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001977888.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001977889.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001977890.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001977891.1 yhch00567 YP_001977892.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001977893.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001977894.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001977895.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001977896.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001977897.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001977898.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001977899.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001977900.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001977901.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001977902.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001977903.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001977904.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001977905.1 one of the stabilizing components for the large ribosomal subunit YP_001977906.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001977907.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001977908.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001977909.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001977910.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001977911.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001977912.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001977913.1 binds 5S rRNA along with protein L5 and L25 YP_001977914.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001977915.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001977916.1 late assembly protein YP_001977917.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001977918.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001977919.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001977920.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001977921.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001977922.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001977923.1 ypch00587 YP_001977924.1 yhch00568 YP_001977925.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001977926.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001977927.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001977928.1 yhch00569 YP_001977929.1 yhch00570 YP_001977931.1 related to helicase; ypch00590 YP_001977932.1 yhch00571 YP_001977933.1 yhch00572 YP_001977934.1 yhch00573 YP_001977935.1 ypch00591 YP_001977936.1 ypch00592 YP_001977937.1 ypch00593 YP_001977938.1 ypch00594 YP_001977939.1 yhch00574 YP_001977940.1 ypch00595 YP_001977941.1 yhch00575 YP_001977942.1 ypch00596 YP_001977943.1 ypch00597 YP_001977944.1 ypch00598 YP_001977945.1 ypch00599 YP_001977946.1 ypch00600 YP_001977947.1 ypch00601 YP_001977948.1 ypch00602 YP_001977949.1 ypch00603 YP_001977950.1 ypch00604 YP_001977951.1 ypch00605 YP_001977952.1 ypch00606 YP_001977953.1 ypch00607 YP_001977954.1 yhch00576 YP_001977955.1 yhch00577 YP_001977957.1 ypch00608 YP_001977958.1 yhch00578 YP_001977959.1 yhch00579 YP_001977960.1 ypch00609 YP_001977961.1 ypch00610 YP_001977962.1 yhch00580 YP_001977963.1 ypch00611 YP_001977964.1 yhch00581 YP_001977965.1 yhch00582 YP_001977966.1 yhch00583 YP_001977967.1 yhch00584 YP_001977968.1 yhch00585 YP_001977969.1 yhch00586 YP_001977970.1 yhch00587 YP_001977971.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_001977972.1 ypch00612 YP_001977973.1 ypch00613 YP_001977974.1 ypch00614 YP_001977975.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine YP_001977976.1 ypch00615 YP_001977978.1 yhch00588 YP_001977979.1 yhch00589 YP_001977980.1 yhch00590 YP_001977981.1 ypch00616 YP_001977982.1 ypch00617 YP_001977983.1 ypch00618 YP_001977984.1 ypch00619 YP_001977985.1 yhch00591 YP_001977986.1 yhch00592 YP_001977987.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001977988.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001977989.1 ypch00621 YP_001977990.1 related to molybdopterin-biosynthesis enzyme MoeA YP_001977991.1 yhch00593 YP_001977992.1 yhch00594 YP_001977993.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_001977994.1 yhch00595 YP_001977995.1 ypch00622 YP_001977996.1 ypch00623 YP_001977997.1 ypch00624 YP_001977998.1 ypch00625 YP_001978000.1 ypch00626 YP_001978001.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001978002.1 yhch00596 YP_001978003.1 yhch00597 YP_001978006.1 yhch00598 YP_001978007.1 ypch00627 YP_001978010.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001978012.1 ypch00628 YP_001978014.1 yhch00599 YP_001978015.1 ypch00629 YP_001978017.1 yhch00600 YP_001978018.1 ypch00630 YP_001978022.1 ypch00631 YP_001978025.1 yhch00601 YP_001978026.1 ypch00632 YP_001978027.1 ypch00633 YP_001978028.1 yhch00602 YP_001978030.1 yhch00603 YP_001978031.1 yhch00604 YP_001978032.1 yhch00605 YP_001978033.1 yhch00606 YP_001978034.1 yhch00607 YP_001978035.1 yhch00608 YP_001978036.1 yhch00609 YP_001978037.1 yhch00610 YP_001978038.1 yhch00611 YP_001978039.1 yhch00612 YP_001978041.1 yhch00613 YP_001978042.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001978043.1 ypch00634 YP_001978044.1 yhch00614 YP_001978047.1 yhch00615 YP_001978048.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001978049.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001978050.1 yhch00616 YP_001978051.1 ypch00635 YP_001978054.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001978055.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_001978057.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001978058.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001978059.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001978061.1 yhch00617 YP_001978063.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001978064.1 yhch00618 YP_001978066.1 yhch00619 YP_001978067.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_001978068.1 yhch00620 YP_001978069.1 yhch00621 YP_001978070.1 yhch00622 YP_001978071.1 yhch00623 YP_001978072.1 yhch00624 YP_001978073.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001978074.1 yhch00625 YP_001978075.1 yhch00626 YP_001978076.1 yhch00627 YP_001978077.1 catalyzes the conversion of NADPH to NADH YP_001978079.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001978080.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001978081.1 ypch00636 YP_001978082.1 yhch00628 YP_001978083.1 yhch00629 YP_001978084.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001978085.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins YP_001978086.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001978087.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001978088.1 yhch00630 YP_001978089.1 yhch00631 YP_001978090.1 ypch00638 YP_001978091.1 ypch00639 YP_001978092.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001978093.1 ypch00640 YP_001978094.1 ypch00641 YP_001978095.1 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis YP_001978096.1 yhch00632 YP_001978097.1 yhch00633 YP_001978098.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001978099.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001978100.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001978101.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001978102.1 ypch00643 YP_001978104.1 yhch00634 YP_001978106.1 yhch00635 YP_001978108.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001978109.1 yhch00636 YP_001978111.1 yhch00637 YP_001978114.1 yhch00638 YP_001978115.1 yhch00639 YP_001978116.1 ypch00644 YP_001978117.1 yhch00640 YP_001978118.1 yhch00641 YP_001978119.1 ypch00645 YP_001978120.1 yhch00642 YP_001978121.1 yhch00643 YP_001978122.1 yhch00644 YP_001978123.1 yhch00645 YP_001978124.1 yhch00646 YP_001978125.1 yhch00647 YP_001978130.1 yhch00648 YP_001978131.1 catalyzes the formation of L-homocysteine from cystathionine YP_001978132.1 ypch00646 YP_001978133.1 yhch00649 YP_001978134.1 ypch00647 YP_001978136.1 yhch00650 YP_001978137.1 yhch00651 YP_001978138.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001978140.1 ypch00648 YP_001978141.1 yhch00652 YP_001978142.1 ypch00649 YP_001978143.1 ypch00650 YP_001978144.1 yhch00653 YP_001978145.1 ypch00651 YP_001978146.1 yhch00654 YP_001978147.1 yhch00655 YP_001978148.1 yhch00656 YP_001978149.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001978150.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001978151.1 Catalyzes the phosphorylation of UMP to UDP YP_001978152.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001978157.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001978158.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001978159.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001978160.1 yhch00657 YP_001978161.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001978162.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001978163.1 yhch00658 YP_001978164.1 Represses a number of genes involved in the response to DNA damage YP_001978165.1 yhch00659 YP_001978166.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001978167.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001978168.1 ypch00652 YP_001978170.1 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase YP_001978172.1 ypch00653 YP_001978173.1 ypch00654 YP_001978174.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001978175.1 yhch00660 YP_001978176.1 ypch00655 YP_001978177.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001978178.1 yhch00661 YP_001978179.1 ypch00657 YP_001978180.1 related to molybdopterin-biosynthesis enzyme MoeA YP_001978181.1 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations YP_001978185.1 yhch00662 YP_001978186.1 yhch00663 YP_001978187.1 yhch00664 YP_001978188.1 ypch00658 YP_001978189.1 ypch00659 YP_001978190.1 yhch00665 YP_001978191.1 ypch00660 YP_001978192.1 catalyzes the formation of pyruvate from serine YP_001978193.1 ypch00662 YP_001978194.1 ypch00663 YP_001978195.1 ypch00664 YP_001978196.1 ypch00665 YP_001978197.1 ypch00666 YP_001978199.1 bifunctional folD2 YP_001978200.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001978203.1 catalyzes the transamination of D-amino acids and their alpha-keto acids YP_001978204.1 Stimulates the elongation of poly(A) tails YP_001978206.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era YP_001978207.1 ypch00668 YP_001978208.1 yhch00666 YP_001978210.1 yhch00667 YP_001978212.1 yhch00668 YP_001978216.1 yhch00669 YP_001978217.1 yhch00670 YP_001978218.1 yhch00671 YP_001978219.1 yhch00672 YP_001978221.1 yhch00673 YP_001978222.1 ypch00669 YP_001978223.1 yhch00674 YP_001978225.1 ypch00670 YP_001978226.1 ypch00671 YP_001978227.1 ypch00672 YP_001978228.1 yhch00675 YP_001978229.1 yhch00676 YP_001978230.1 ypch00673 YP_001978231.1 yhch00677 YP_001978232.1 yhch00678 YP_001978233.1 yhch00679 YP_001978234.1 yhch00680 YP_001978235.1 ypch00674 YP_001978236.1 ypch00675 YP_001978237.1 ypch00676 YP_001978238.1 ypch00677 YP_001978239.1 ypch00678 YP_001978240.1 ypch00679 YP_001978241.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate YP_001978243.1 ypch00680 YP_001978249.1 ypch00681 YP_001978250.1 ypch00682 YP_001978251.1 ypch00683 YP_001978252.1 ypch00684 YP_001978253.1 ypch00685 YP_001978254.1 ypch00686 YP_001978255.1 yhch00682 YP_001978256.1 yhch00683 YP_001978257.1 yhch00684 YP_001978258.1 yhch00685 YP_001978259.1 ypch00687 YP_001978260.1 ypch00688 YP_001978261.1 ypch00689 YP_001978262.1 yhch00686 YP_001978263.1 ypch00690 YP_001978267.1 ypch00691 YP_001978268.1 ypch00692 YP_001978269.1 ypch00693 YP_001978270.1 ypch00694 YP_001978271.1 ypch00695 YP_001978272.1 ypch00696 YP_001978273.1 ypch00697 YP_001978274.1 membrane component of a sugar ABC transporter system YP_001978275.1 ypch00699 YP_001978276.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001978277.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001978278.1 yhch00687 YP_001978279.1 catalyzes branch migration in Holliday junction intermediates YP_001978280.1 yhch00688 YP_001978282.1 ypch00700 YP_001978283.1 yhch00689 YP_001978284.1 yhch00690 YP_001978285.1 ypch00701 YP_001978286.1 ypch00702 YP_001978287.1 ypch00703 YP_001978288.1 yhch00691 YP_001978291.1 ypch00704 YP_001978292.1 yhch00692 YP_001978293.1 ypch00705 YP_001978294.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001978295.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_001978296.1 ypch00706 YP_001978297.1 negatively supercoils closed circular double-stranded DNA YP_001978298.1 yhch00693 YP_001978299.1 yhch00694 YP_001978300.1 yhch00695 YP_001978301.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001978304.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001978305.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001978306.1 ypch00707 YP_001978307.1 yhch00696 YP_001978308.1 FabF, beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. YP_001978309.1 ypch00708 YP_001978310.1 ypch00709 YP_001978311.1 ypch00710 YP_001978317.1 ypch00711 YP_001978318.1 yhch00697 YP_001978319.1 yhch00698 YP_001978320.1 yhch00699 YP_001978321.1 yhch00700 YP_001978322.1 ypch00712 YP_001978323.1 ypch00713 YP_001978324.1 ypch00714 YP_001978325.1 ypch00715 YP_001978326.1 ypch00717 YP_001978327.1 ypch00718 YP_001978328.1 ypch00719 YP_001978329.1 ypch00720 YP_001978330.1 ypch00721 YP_001978331.1 ypch00722 YP_001978335.1 ypch00723 YP_001978338.1 ypch00724 YP_001978340.1 ypch00725 YP_001978341.1 ypch00726 YP_001978342.1 yhch00701 YP_001978343.1 yhch00702 YP_001978344.1 yhch00703 YP_001978345.1 yhch00704 YP_001978346.1 yhch00705 YP_001978347.1 yhch00706 YP_001978348.1 yhch00707 YP_001978349.1 ypch00727 YP_001978350.1 ypch00728 YP_001978351.1 yhch00708 YP_001978352.1 ypch00729 YP_001978353.1 yhch00709 YP_001978354.1 ypch00730 YP_001978355.1 ypch00731 YP_001978356.1 yhch00710 YP_001978357.1 yhch00711 YP_001978358.1 yhch00712 YP_001978359.1 yhch00713 YP_001978360.1 ypch00732 YP_001978361.1 yhch00714 YP_001978362.1 yhch00715 YP_001978363.1 yhch00716 YP_001978364.1 yhch00717 YP_001978365.1 yhch00718 YP_001978366.1 ypch00734 YP_001978367.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001978368.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001978369.1 ypch00737 YP_001978370.1 yhch00719 YP_001978371.1 yhch00720 YP_001978372.1 yhch00721 YP_001978373.1 ypch00738 YP_001978374.1 ypch00739 YP_001978375.1 ypch00740 YP_001978376.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001978377.1 yhch00722 YP_001978378.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001978379.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001978383.1 ypch00741 YP_001978384.1 ypch00742 YP_001978385.1 ypch00743 YP_001978386.1 ypch00744 YP_001978388.1 ypch00745 YP_001978389.1 ypch00746 YP_001978390.1 yhch00723 YP_001978391.1 yhch00724 YP_001978392.1 yhch00725 YP_001978394.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001978395.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001978398.1 ypch00747 YP_001978401.1 yhch00726 YP_001978403.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle YP_001978404.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001978405.1 ypch00748 YP_001978406.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001978407.1 yhch00727 YP_001978408.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001978409.1 yhch00728 YP_001978410.1 ypch00749 YP_001978411.1 ypch00750 YP_001978412.1 yhch00729 YP_001978413.1 yhch00730 YP_001978414.1 yhch00731 YP_001978415.1 ypch00751 YP_001978416.1 yhch00732 YP_001978417.1 yhch00733 YP_001978418.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001978419.1 yhch00734 YP_001978420.1 yhch00735 YP_001978422.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001978423.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_001978424.1 ypch00752 YP_001978425.1 ypch00753 YP_001978426.1 ypch00754 YP_001978427.1 yhch00736 YP_001978428.1 yhch00737 YP_001978429.1 yhch00738 YP_001978431.1 ypch00755 YP_001978432.1 yhch00739 YP_001978433.1 ypch00756 YP_001978434.1 yhch00740 YP_001978435.1 yhch00741 YP_001978437.1 ypch00757 YP_001978441.1 ypch00758 YP_001978442.1 ypch00759 YP_001978443.1 ypch00760 YP_001978444.1 ypch00761 YP_001978445.1 ypch00762 YP_001978446.1 ypch00763 YP_001978447.1 ypch00764 YP_001978448.1 ypch00765 YP_001978449.1 ypch00766 YP_001978450.1 yhch00742 YP_001978451.1 ypch00767 YP_001978452.1 ypch00768 YP_001978453.1 ypch00769 YP_001978454.1 ypch00770 YP_001978455.1 ypch00771 YP_001978456.1 ypch00772 YP_001978457.1 yhch00743 YP_001978458.1 yhch00744 YP_001978459.1 ypch00773 YP_001978460.1 ypch00774 YP_001978461.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001978462.1 yhch00745 YP_001978463.1 yhch00746 YP_001978464.1 yhch00747 YP_001978465.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001978466.1 ypch00775 YP_001978467.1 yhch00748 YP_001978470.1 ypch00776; fusion protein: acetyltransferase (RHE_CH02228) and hypothetical conserved protein (RL2560) YP_001978472.1 yhch00749 YP_001978474.1 yhch00750 YP_001978475.1 ypch00777 YP_001978478.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001978479.1 yhch00751 YP_001978480.1 yhch00752 YP_001978481.1 yhch00753 YP_001978482.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001978483.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001978484.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001978485.1 similar to muramidase (lysozyme) protein YP_001978486.1 ypch00779 YP_001978487.1 yhch00754 YP_001978488.1 yhch00755 YP_001978489.1 yhch00756 YP_001978490.1 ypch00780 YP_001978493.1 yhch00757 YP_001978494.1 with SufCD activates cysteine desulfurase SufS YP_001978496.1 ypch00781 YP_001978498.1 ypch00782 YP_001978499.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001978500.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001978501.1 yhch00758 YP_001978502.1 ypch00783 YP_001978503.1 yhch00759 YP_001978505.1 yhch00760 YP_001978506.1 ypch00784 YP_001978508.1 ypch00785 YP_001978509.1 ypch00786 YP_001978510.1 ypch00787 YP_001978511.1 ypch00788 YP_001978513.1 yhch00761 YP_001978514.1 yhch00762 YP_001978515.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001978516.1 yhch00763 YP_001978517.1 yhch00764 YP_001978518.1 yhch00765 YP_001978519.1 ypch00789 YP_001978520.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001978521.1 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway YP_001978522.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown YP_001978523.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001978524.1 yhch00766 YP_001978525.1 yhch00767 YP_001978526.1 ypch00790 YP_001978527.1 yhch00768 YP_001978528.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001978529.1 ypch00791 YP_001978530.1 yhch00769 YP_001978531.1 yhch00770 YP_001978533.1 ypch00792 YP_001978534.1 ypch00793 YP_001978535.1 ypch00794 YP_001978536.1 ypch00795 YP_001978537.1 ypch00796 YP_001978538.1 yhch00771 YP_001978539.1 catalyzes the formation of glutamate from glutamine YP_001978540.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001978541.1 yhch00772 YP_001978542.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001978543.1 ypch00797 YP_001978544.1 yhch00773 YP_001978545.1 yhch00774 YP_001978546.1 Converts isocitrate to alpha ketoglutarate YP_001978547.1 ypch00798 YP_001978549.1 ypch00799 YP_001978550.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001978551.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001978553.1 yhch00775 YP_001978554.1 ypch00801 YP_001978555.1 yhch00776 YP_001978556.1 yhch00777 YP_001978558.1 yhch00778 YP_001978559.1 ypch00802 YP_001978560.1 yhch00779 YP_001978561.1 yhch00780 YP_001978562.1 yhch00781 YP_001978566.1 yhch00782 YP_001978568.1 yhch00783 YP_001978569.1 yhch00784 YP_001978570.1 ypch00803 YP_001978571.1 yhch00785 YP_001978572.1 ypch00804 YP_001978573.1 ypch00805 YP_001978574.1 ypch00806 YP_001978575.1 ypch00807 YP_001978576.1 ypch00808 YP_001978577.1 ypch00809 YP_001978578.1 ypch00810 YP_001978579.1 ypch00811 YP_001978581.1 ypch00812 YP_001978582.1 ypch00813 YP_001978583.1 yhch00786 YP_001978584.1 NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate YP_001978585.1 yhch00787 YP_001978586.1 ypch00814 YP_001978587.1 yhch00788 YP_001978588.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001978589.1 yhch00789 YP_001978590.1 ypch00815 YP_001978591.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001978592.1 yhch00790 YP_001978593.1 ypch00816 YP_001978594.1 yhch00791 YP_001978596.1 yhch00792 YP_001978597.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001978598.1 yhch00793 YP_001978599.1 catalyzes the hydrolysis of acylphosphate YP_001978600.1 yhch00794 YP_001978601.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001978602.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001978603.1 yhch00795 YP_001978604.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001978605.1 ypch00819 YP_001978608.1 yhch00796 YP_001978609.1 ypch00820 YP_001978610.1 ypch00821 YP_001978611.1 yhch00797 YP_001978612.1 ypch00822 YP_001978613.1 yhch00798 YP_001978614.1 yhch00799 YP_001978615.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001978616.1 ypch00823 YP_001978617.1 ypch00824 YP_001978618.1 ypch00825 YP_001978619.1 ypch00826 YP_001978620.1 ypch00827 YP_001978627.1 ypch00828 YP_001978628.1 ypch00829 YP_001978629.1 ypch00830 YP_001978630.1 yhch00800 YP_001978631.1 yhch00801 YP_001978634.1 ypch00831 YP_001978635.1 ypch00832 YP_001978636.1 ypch00833 YP_001978637.1 yhch00802 YP_001978638.1 ypch00834 YP_001978639.1 ypch00835 YP_001978640.1 ypch00836 YP_001978641.1 ypch00837 YP_001978642.1 ypch00838 YP_001978643.1 ypch00839 YP_001978644.1 ypch00840 YP_001978645.1 ypch00841 YP_001978646.1 ypch00842 YP_001978647.1 ypch00843 YP_001978648.1 ypch00844 YP_001978649.1 ypch00845 YP_001978650.1 ypch00846 YP_001978651.1 yhch00803 YP_001978652.1 ypch00847 YP_001978654.1 ypch00848 YP_001978655.1 yhch00804 YP_001978656.1 yhch00805 YP_001978657.1 yhch00806 YP_001978658.1 yhch00807 YP_001978659.1 ypch00849 YP_001978660.1 yhch00808 YP_001978661.1 ypch00850 YP_001978662.1 yhch00809 YP_001978663.1 yhch00810 YP_001978664.1 ypch00851 YP_001978665.1 yhch00811 YP_001978666.1 ypch00852 YP_001978668.1 yhch00812 YP_001978669.1 ypch00853 YP_001978670.1 ypch00854 YP_001978671.1 ypch00855 YP_001978672.1 ypch00856 YP_001978674.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001978675.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001978676.1 yhch00813 YP_001978677.1 yhch00814 YP_001978678.1 ypch00857 YP_001978679.1 yhch00815 YP_001978680.1 yhch00816 YP_001978681.1 ypch00858 YP_001978682.1 ypch00859 YP_001978685.1 ypch00860 YP_001978687.1 ypch00861 YP_001978688.1 ypch00862 YP_001978689.1 ypch00863 YP_001978691.1 ypch00864 YP_001978692.1 ypch00865 YP_001978693.1 ypch00866 YP_001978694.1 ypch00867 YP_001978695.1 ypch00868 YP_001978696.1 yhch00817 YP_001978697.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001978698.1 yhch00818 YP_001978699.1 yhch00819 YP_001978700.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001978701.1 ypch00869 YP_001978702.1 yhch00820 YP_001978703.1 ypch00870 YP_001978704.1 yhch00821 YP_001978705.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001978706.1 ypch00871 YP_001978707.1 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. YP_001978708.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001978709.1 ypch00874 YP_001978710.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_001978712.1 yhch00822 YP_001978713.1 yhch00823 YP_001978714.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_001978716.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001978719.1 ypch00875 YP_001978720.1 yhch00824 YP_001978721.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001978722.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_001978724.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_001978725.1 yhch00825 YP_001978727.1 ypch00876 YP_001978728.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001978729.1 yhch00826 YP_001978730.1 ypch00877 YP_001978731.1 yhch00827 YP_001978733.1 ypch00878 YP_001978734.1 yhch00828 YP_001978735.1 ypch00879 YP_001978736.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001978737.1 activates RNA polymerase to cleave back-tracked RNA during elongational pausing YP_001978738.1 ypch00881 YP_001978739.1 yhch00829 YP_001978740.1 yhch00830 YP_001978741.1 yhch00831 YP_001978742.1 yhch00832 YP_001978743.1 ypch00882 YP_001978744.1 yhch00833 YP_001978745.1 yhch00834 YP_001978746.1 ypch00883 YP_001978747.1 ypch00884 YP_001978749.1 yhch00835 YP_001978750.1 ypch00885 YP_001978751.1 ypch00886 YP_001978752.1 ypch00887 YP_001978754.1 yhch00836 YP_001978755.1 ypch00888 YP_001978756.1 yhch00837 YP_001978757.1 ypch00889 YP_001978758.1 ypch00890 YP_001978759.1 ypch00891 YP_001978760.1 ypch00892 YP_001978761.1 ypch00893 YP_001978762.1 yhch00838 YP_001978763.1 ypch00894 YP_001978764.1 ypch00895 YP_001978766.1 ypch00896 YP_001978767.1 ypch00897 YP_001978768.1 ypch00898 YP_001978770.1 yhch00839 YP_001978771.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_001978772.1 yhch00840 YP_001978773.1 ypch00900 YP_001978774.1 ypch00901 YP_001978775.1 yhch00841 YP_001978776.1 yhch00842 YP_001978777.1 yhch00843 YP_001978778.1 ypch00902 YP_001978779.1 ypch00903 YP_001978782.1 yhch00844 YP_001978783.1 yhch00845 YP_001978784.1 yhch00846 YP_001978786.1 ypch00904 YP_001978787.1 yhch00847 YP_001978788.1 yhch00848 YP_001978789.1 yhch00849 YP_001978790.1 yhch00850 YP_001978791.1 ypch00905 YP_001978792.1 yhch00851 YP_001978793.1 ypch00906 YP_001978794.1 yhch00852 YP_001978795.1 LovR from Caulobacter crescentus is a response regulator part of a two-component signaling system that regulates photosensitive bacterial cell-surface and cell-cell attachment YP_001978796.1 yhch00853 YP_001978797.1 yhch00854 YP_001978798.1 ypch00908 YP_001978799.1 yhch00855 YP_001978800.1 yhch00856 YP_001978801.1 yhch00857 YP_001978802.1 yhch00858 YP_001978803.1 yhch00859 YP_001978804.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001978805.1 ypch00909 YP_001978806.1 yhch00860 YP_001978807.1 yhch00861 YP_001978808.1 yhch00862 YP_001978809.1 yhch00863 YP_001978811.1 yhch00864 YP_001978812.1 ypch00910 YP_001978813.1 ypch00911 YP_001978814.1 ypch00912 YP_001978815.1 yhch00865 YP_001978816.1 yhch00866 YP_001978817.1 yhch00867 YP_001978818.1 yhch00868 YP_001978819.1 yhch00869 YP_001978820.1 yhch00870 YP_001978821.1 ypch00913 YP_001978822.1 ypch00914 YP_001978823.1 yhch00871 YP_001978824.1 ypch00915 YP_001978825.1 ypch00916 YP_001978826.1 yhch00872 YP_001978827.1 ypch00917 YP_001978828.1 yhch00873 YP_001978829.1 ypch00918 YP_001978830.1 ypch00919 YP_001978831.1 yhch00874 YP_001978832.1 yhch00875 YP_001978833.1 ypch00920 YP_001978834.1 yhch00876 YP_001978835.1 yhch00877 YP_001978836.1 yhch00878 YP_001978837.1 ypch00921 YP_001978838.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001978839.1 yhch00879 YP_001978840.1 yhch00880 YP_001978841.1 ypch00922 YP_001978842.1 yhch00881 YP_001978843.1 ypch00923 YP_001978844.1 yhch00882 YP_001978845.1 yhch00883 YP_001978846.1 yhch00884 YP_001978847.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001978848.1 ypch00924 YP_001978849.1 ypch00925 YP_001978850.1 yhch00885 YP_001978851.1 ypch00926 YP_001978852.1 ypch00927 YP_001978854.1 yhch00886 YP_001978855.1 yhch00887 YP_001978856.1 yhch00888 YP_001978857.1 ypch00928 YP_001978860.1 ypch00929 YP_001978863.1 yhch00889 YP_001978864.1 yhch00890 YP_001978865.1 yhch00891 YP_001978866.1 ypch00930 YP_001978867.1 ypch00931 YP_001978868.1 ypch00932 YP_001978869.1 ypch00933 YP_001978870.1 ypch00934 YP_001978871.1 yhch00892 YP_001978872.1 yhch00893 YP_001978877.1 ypch00935 YP_001978878.1 ypch00936 YP_001978879.1 yhch00894 YP_001978880.1 ypch00937 YP_001978881.1 yhch00895 YP_001978882.1 yhch00896 YP_001978883.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001978884.1 ypch00938; fusion protein: autoaggregation protein (RL3074) and hypothetical conserved protein (RL3073) YP_001978885.1 yhch00897 YP_001978886.1 ypch00939 YP_001978887.1 ypch00940 YP_001978888.1 yhch00898 YP_001978889.1 yhch00899 YP_001978890.1 yhch00900 YP_001978891.1 yhch00902 YP_001978892.1 yhch00903 YP_001978893.1 yhch00904 YP_001978894.1 yhch00905 YP_001978895.1 ypch00941 YP_001978896.1 ypch00942 YP_001978897.1 ypch00943 YP_001978901.1 yhch00906 YP_001978902.1 ypch00944 YP_001978903.1 yhch00907 YP_001978904.1 ypch00945 YP_001978905.1 ypch00946 YP_001978906.1 yhch00908 YP_001978907.1 yhch00909 YP_001978908.1 yhch00910 YP_001978909.1 yhch00911 YP_001978910.1 yhch00912 YP_001978911.1 yhch00913 YP_001978912.1 ypch00947 YP_001978913.1 yhch00914 YP_001978914.1 ypch00948 YP_001978915.1 yhch00915 YP_001978916.1 ypch00949 YP_001978917.1 ypch00950 YP_001978918.1 ypch00951 YP_001978919.1 yhch00916 YP_001978921.1 yhch00917 YP_001978923.1 ypch00952 YP_001978924.1 ypch00953 YP_001978925.1 ypch00954 YP_001978926.1 ypch00955 YP_001978927.1 ypch00956 YP_001978928.1 yhch00918 YP_001978929.1 ypch00957 YP_001978930.1 ypch00958 YP_001978931.1 yhch00919 YP_001978932.1 ypch00959 YP_001978933.1 ypch00960 YP_001978934.1 ypch00961 YP_001978935.1 yhch00920 YP_001978936.1 yhch00921 YP_001978937.1 yhch00922 YP_001978938.1 yhch00923 YP_001978939.1 unwinds double stranded DNA YP_001978940.1 yhch00924 YP_001978941.1 ypch00963 YP_001978942.1 ypch00964 YP_001978943.1 ypch00965 YP_001978944.1 ypch00966 YP_001978945.1 ypch00967 YP_001978946.1 ypch00968 YP_001978947.1 ypch00969 YP_001978948.1 ypch00970 YP_001978949.1 ypch00971 YP_001978950.1 ypch00972 YP_001978951.1 yhch00925 YP_001978952.1 yhch00926 YP_001978953.1 yhch00927 YP_001978954.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001978955.1 ypch00973 YP_001978956.1 yhch00928 YP_001978957.1 ypch00974 YP_001978958.1 ypch00975 YP_001978959.1 ypch00976 YP_001978960.1 yhch00929 YP_001978961.1 ypch00977 YP_001978963.1 ypch00978 YP_001978964.1 yhch00930 YP_001978965.1 ypch00979 YP_001978966.1 ypch00980 YP_001978967.1 ypch00981 YP_001978968.1 ypch00982 YP_001978969.1 ypch00983 YP_001978970.1 yhch00931 YP_001978971.1 yhch00932 YP_001978972.1 yhch00933 YP_001978973.1 yhch00934 YP_001978978.1 ypch00984 YP_001978979.1 yhch00935 YP_001978980.1 yhch00936 YP_001978981.1 ypch00985 YP_001978982.1 ypch00986 YP_001978983.1 ypch00987 YP_001978986.1 yhch00937 YP_001978987.1 yhch00938 YP_001978988.1 yhch00939 YP_001978989.1 yhch00940 YP_001978990.1 yhch00941 YP_001978991.1 ypch00988 YP_001978992.1 ypch00989 YP_001978993.1 ypch00990 YP_001978997.1 ypch00991 YP_001978998.1 ypch00992 YP_001979000.1 ypch00993 YP_001979001.1 yhch00942 YP_001979002.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001979003.1 ypch00994 YP_001979004.1 ypch00995 YP_001979005.1 yhch00943 YP_001979006.1 ypch00996 YP_001979007.1 ypch00997 YP_001979008.1 yhch00944 YP_001979009.1 ypch00998 YP_001979010.1 yhch00945 YP_001979011.1 yhch00946 YP_001979012.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001979013.1 ypch00999 YP_001979014.1 yhch00947 YP_001979016.1 ypch01000 YP_001979021.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001979022.1 ypch01001 YP_001979023.1 yhch00948 YP_001979024.1 ypch01002 YP_001979025.1 ypch01003 YP_001979027.1 ypch01004 YP_001979029.1 yhch00949 YP_001979030.1 yhch00950 YP_001979031.1 ypch01005 YP_001979032.1 ypch01006 YP_001979033.1 ypch01007 YP_001979034.1 ypch01008 YP_001979035.1 ypch01009 YP_001979036.1 ypch01010 YP_001979037.1 yhch00951 YP_001979038.1 yhch00952 YP_001979039.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001979040.1 ypch01011 YP_001979042.1 ypch01012 YP_001979043.1 ypch01013 YP_001979044.1 yhch00953 YP_001979045.1 ypch01014 YP_001979046.1 ypch01015 YP_001979047.1 ypch01016 YP_001979049.1 yhch00954 YP_001979050.1 yhch00955 YP_001979053.1 ypch01017 YP_001979054.1 yhch00956 YP_001979055.1 ypch01018 YP_001979056.1 ypch01019 YP_001979057.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001979059.1 yhch00957 YP_001979060.1 yhch00958 YP_001979062.1 ypch01020 YP_001979063.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001979069.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001979070.1 yhch00959 YP_001979071.1 yhch00960 YP_001979072.1 yhch00961 YP_001979073.1 yhch00962 YP_001979074.1 yhch00963 YP_001979077.1 ypch01022 YP_001979078.1 ypch01023 YP_001979079.1 ypch01024 YP_001979080.1 yhch00964 YP_001979081.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001979082.1 ypch01025 YP_001979083.1 yhch00965 YP_001979086.1 ypch01026 YP_001979087.1 ypch01027 YP_001979089.1 yhch00966 YP_001979090.1 yhch00967 YP_001979091.1 ypch01028 YP_001979092.1 yhch00968 YP_001979093.1 ypch01029 YP_001979094.1 yhch00969 YP_001979095.1 ypch01030 YP_001979097.1 yhch00970 YP_001979099.1 yhch00971 YP_001979100.1 ypch01031 YP_001979101.1 yhch00972 YP_001979102.1 ypch01032 YP_001979103.1 yhch00973 YP_001979104.1 ypch01033 YP_001979105.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001979109.1 yhch00974 YP_001979110.1 ypch01034 YP_001979111.1 ypch01035 YP_001979112.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001979113.1 yhch00975 YP_001979116.1 yhch00976 YP_001979117.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001979118.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001979121.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001979122.1 ypch01036 YP_001979123.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001979124.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001979125.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001979127.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001979128.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001979130.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001979132.1 yhch00977 YP_001979134.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001979135.1 ypch01037 YP_001979136.1 ypch01038 YP_001979137.1 ypch01039 YP_001979138.1 ypch01040 YP_001979140.1 yhch00978 YP_001979141.1 catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate YP_001979142.1 ypch01041 YP_001979143.1 ypch01042 YP_001979144.1 ypch01043 YP_001979148.1 ypch01044 YP_001979149.1 ypch01045 YP_001979151.1 ypch01046 YP_001979152.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001979153.1 ypch01048 YP_001979154.1 ypch01049 YP_001979155.1 ypch01050 YP_001979156.1 ypch01051 YP_001979158.1 ypch01052 YP_001979159.1 yhch00979 YP_001979160.1 yhch00980 YP_001979161.1 yhch00981 YP_001979163.1 ypch01053 YP_001979164.1 ypch01054 YP_001979166.1 ypch01055 YP_001979167.1 ypch01056 YP_001979168.1 ypch01057 YP_001979169.1 ypch01058 YP_001979170.1 ypch01059 YP_001979171.1 ypch01060 YP_001979172.1 ypch01061 YP_001979173.1 ypch01062 YP_001979174.1 ypch01063 YP_001979175.1 ypch01064 YP_001979176.1 ypch01065 YP_001979177.1 ypch01066 YP_001979178.1 yhch00982 YP_001979179.1 ypch01067 YP_001979180.1 ypch01068 YP_001979181.1 yhch00983 YP_001979182.1 yhch00984 YP_001979183.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001979184.1 ypch01069 YP_001979185.1 yhch00985 YP_001979186.1 ypch01070 YP_001979187.1 ypch01071 YP_001979188.1 ypch01072 YP_001979189.1 ypch01073 YP_001979190.1 ypch01074 YP_001979191.1 ypch01075 YP_001979192.1 ypch01076 YP_001979193.1 yhch00986 YP_001979194.1 yhch00987 YP_001979195.1 yhch00988 YP_001979196.1 yhch00989 YP_001979197.1 yhch00990 YP_001979198.1 yhch00991 YP_001979201.1 yhch00992 YP_001979202.1 ypch01077 YP_001979203.1 yhch00993 YP_001979204.1 yhch00994 YP_001979205.1 yhch00995 YP_001979206.1 yhch00996 YP_001979207.1 yhch00997 YP_001979208.1 yhch00998 YP_001979209.1 yhch00999 YP_001979210.1 yhch01000 YP_001979211.1 yhch01001 YP_001979212.1 yhch01002 YP_001979213.1 yhch01003 YP_001979214.1 yhch01004 YP_001979215.1 yhch01005 YP_001979216.1 yhch01006 YP_001979217.1 yhch01007 YP_001979218.1 yhch01008 YP_001979219.1 yhch01009 YP_001979220.1 yhch01010 YP_001979221.1 yhch01011 YP_001979222.1 yhch01012 YP_001979223.1 yhch01013 YP_001979224.1 yhch01014 YP_001979225.1 yhch01015 YP_001979226.1 yhch01016 YP_001979227.1 yhch01017 YP_001979228.1 yhch01018 YP_001979229.1 yhch01019 YP_001979230.1 yhch01020 YP_001979231.1 yhch01021 YP_001979232.1 yhch01022 YP_001979233.1 yhch01023 YP_001979234.1 yhch01024 YP_001979235.1 ypch01078 YP_001979236.1 ypch01079 YP_001979237.1 ypch01080 YP_001979238.1 yhch01025 YP_001979239.1 yhch01026 YP_001979240.1 yhch01027 YP_001979241.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001979242.1 yhch01028 YP_001979243.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001979244.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001979246.1 synthesizes RNA primers at the replication forks YP_001979247.1 yhch01029 YP_001979248.1 yhch01030 YP_001979249.1 yhch01031 YP_001979250.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001979251.1 ypch01081 YP_001979252.1 yhch01032 YP_001979253.1 yhch01033 YP_001979254.1 ypch01082 YP_001979255.1 ypch01083 YP_001979256.1 ypch01084 YP_001979257.1 ypch01085 YP_001979258.1 ypch01086 YP_001979259.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001979260.1 ypch01087 YP_001979261.1 yhch01034 YP_001979262.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001979264.1 involved in the transport of C4-dicarboxylates across the membrane YP_001979269.1 ypch01088 YP_001979270.1 ypch01089 YP_001979273.1 yhch01035 YP_001979274.1 ypch01090 YP_001979275.1 yhch01036 YP_001979276.1 yhch01037 YP_001979280.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001979281.1 ypch01091 YP_001979282.1 ypch01092 YP_001979283.1 ypch01093 YP_001979284.1 ypch01094 YP_001979285.1 yhch01038 YP_001979286.1 ypch01095 YP_001979287.1 yhch01039 YP_001979289.1 yhch01040 YP_001979290.1 ypch01096 YP_001979291.1 ypch01097 YP_001979292.1 ypch01098 YP_001979293.1 ypch01099 YP_001979294.1 ypch01100 YP_001979295.1 yhch01041 YP_001979296.1 yhch01042 YP_001979297.1 ypch01101 YP_001979299.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001979300.1 yhch01043 YP_001979301.1 yhch01044 YP_001979302.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001979303.1 yhch01045 YP_001979304.1 yhch01046 YP_001979305.1 ypch01102 YP_001979306.1 yhch01047 YP_001979307.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001979308.1 yhch01048 YP_001979309.1 yhch01049 YP_001979310.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001979311.1 ypch01103 YP_001979312.1 ypch01104 YP_001979313.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001979314.1 ypch01105 YP_001979315.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001979316.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001979317.1 yhch01050 YP_001979318.1 ypch01108 YP_001979319.1 ypch01109 YP_001979320.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001979324.1 ypch01110 YP_001979325.1 ypch01111 YP_001979326.1 yhch01051 YP_001979327.1 ypch01112 YP_001979328.1 yhch01052 YP_001979329.1 ypch01113 YP_001979330.1 ypch01114 YP_001979331.1 yhch01053 YP_001979332.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001979333.1 yhch01054 YP_001979334.1 yhch01055 YP_001979336.1 ypch01115 YP_001979337.1 yhch01056 YP_001979338.1 ypch01116 YP_001979339.1 yhch01057 YP_001979340.1 yhch01058 YP_001979341.1 yhch01059 YP_001979342.1 ypch01117 YP_001979343.1 ypch01118 YP_001979344.1 ypch01119 YP_001979345.1 ypch01120 YP_001979346.1 ypch01121 YP_001979347.1 yhch01060 YP_001979349.1 yhch01061 YP_001979351.1 ypch01122 YP_001979352.1 ypch01123 YP_001979353.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001979354.1 yhch01062 YP_001979355.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_001979356.1 ypch01125 YP_001979357.1 yhch01063 YP_001979358.1 yhch01064 YP_001979359.1 trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II YP_001979360.1 ypch01126 YP_001979361.1 yhch01065 YP_001979362.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001979363.1 yhch01066 YP_001979364.1 yhch01067 YP_001979365.1 ypch01127 YP_001979366.1 yhch01068 YP_001979367.1 yhch01069 YP_001979368.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001979372.1 yhch01070 YP_001979374.1 catalyze the conversion of beta amino acids to the corresponding beta keto acid with pyruvate as the amine acceptor YP_001979375.1 ypch01129 YP_001979376.1 yhch01071 YP_001979379.1 yhch01072 YP_001979380.1 ypch01130 YP_001979386.1 yhch01073 YP_001979390.1 ypch01131 YP_001979391.1 ypch01132 YP_001979392.1 yhch01074 YP_001979393.1 ypch01133 YP_001979394.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001979395.1 yhch01075 YP_001979396.1 ypch01134 YP_001979397.1 yhch01076 YP_001979398.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_001979399.1 ypch01135 YP_001979400.1 ypch01136 YP_001979401.1 yhch01077 YP_001979402.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential YP_001979403.1 ypch01137 YP_001979404.1 yhch01078 YP_001979405.1 ypch01138 YP_001979406.1 yhch01079 YP_001979412.1 yhch01080 YP_001979413.1 ypch01139 YP_001979414.1 yhch01081 YP_001979415.1 yhch01082 YP_001979416.1 yhch01083 YP_001979417.1 Catalyzes the deamination of guanine YP_001979418.1 yhch01084 YP_001979419.1 ypch01140 YP_001979421.1 yhch01085 YP_001979422.1 yhch01086 YP_001979423.1 yhch01087 YP_001979424.1 yhch01088 YP_001979425.1 yhch01089 YP_001979426.1 ypch01141 YP_001979427.1 yhch01090 YP_001979428.1 yhch01091 YP_001979429.1 yhch01092 YP_001979430.1 yhch01093 YP_001979431.1 yhch01094 YP_001979432.1 yhch01095 YP_001979433.1 yhch01096 YP_001979434.1 yhch01097 YP_001979435.1 yhch01098 YP_001979436.1 ypch01142 YP_001979437.1 yhch01099 YP_001979438.1 yhch01100 YP_001979439.1 yhch01101 YP_001979440.1 ypch01143 YP_001979441.1 ypch01144 YP_001979442.1 yhch01102 YP_001979443.1 yhch01103 YP_001979444.1 ypch01145 YP_001979445.1 yhch01104 YP_001979446.1 yhch01105 YP_001979447.1 yhch01106 YP_001979448.1 yhch01107 YP_001979449.1 yhch01108 YP_001979450.1 yhch01109 YP_001979451.1 yhch01110 YP_001979452.1 yhch01111 YP_001979453.1 yhch01112 YP_001979455.1 yhch01113 YP_001979456.1 yhch01114 YP_001979457.1 yhch01115 YP_001979458.1 ypch01146 YP_001979459.1 ypch01147 YP_001979460.1 ypch01148 YP_001979461.1 yhch01116 YP_001979462.1 yhch01117 YP_001979463.1 yhch01118 YP_001979464.1 yhch01119 YP_001979465.1 yhch01120 YP_001979466.1 ypch01149 YP_001979467.1 yhch01121 YP_001979468.1 yhch01122 YP_001979469.1 yhch01123 YP_001979470.1 yhch01124 YP_001979471.1 yhch01125 YP_001979472.1 yhch01126 YP_001979473.1 yhch01127 YP_001979474.1 yhch01128 YP_001979475.1 yhch01129 YP_001979476.1 yhch01130 YP_001979477.1 yhch01131 YP_001979478.1 yhch01132 YP_001979479.1 ypch01150 YP_001979480.1 ypch01151 YP_001979481.1 ypch01152 YP_001979482.1 ypch01153 YP_001979483.1 yhch01133 YP_001979484.1 yhch01134 YP_001979485.1 ypch01154 YP_001979486.1 ypch01155 YP_001979487.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001979488.1 yhch01135 YP_001979489.1 yhch01136 YP_001979490.1 ypch01156 YP_001979491.1 yhch01137 YP_001979492.1 ypch01157 YP_001979493.1 yhch01138 YP_001979494.1 ypch01158 YP_001979495.1 yhch01139 YP_001979496.1 yhch01140 YP_001979497.1 ypch01159 YP_001979499.1 ypch01160 YP_001979500.1 ypch01161 YP_001979502.1 yhch01141 YP_001979503.1 yhch01142 YP_001979504.1 yhch01143 YP_001979505.1 ypch01162 YP_001979506.1 yhch01144 YP_001979507.1 ypch01163 YP_001979508.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001979509.1 ypch01164 YP_001979515.1 yhch01145 YP_001979516.1 yhch01146 YP_001979518.1 ypch01165 YP_001979522.1 ypch01166 YP_001979523.1 ypch01167 YP_001979524.1 ypch01168 YP_001979525.1 ypch01169 YP_001979526.1 ypch01170 YP_001979527.1 ypch01171 YP_001979528.1 ypch01172 YP_001979529.1 yhch01147 YP_001979530.1 yhch01148 YP_001979531.1 yhch01149 YP_001979532.1 yhch01150 YP_001979533.1 yhch01151 YP_001979534.1 ypch01173 YP_001979535.1 yhch01152 YP_001979536.1 yhch01153 YP_001979537.1 ypch01174 YP_001979538.1 yhch01154 YP_001979539.1 yhch01155 YP_001979540.1 ypch01175 YP_001979541.1 ypch01176 YP_001979542.1 yhch01156 YP_001979543.1 yhch01157 YP_001979544.1 ypch01177 YP_001979545.1 ypch01178 YP_001979546.1 yhch01158 YP_001979547.1 yhch01159 YP_001979548.1 yhch01160 YP_001979549.1 ypch01179 YP_001979550.1 ypch01180 YP_001979551.1 yhch01161 YP_001979552.1 yhch01162 YP_001979553.1 yhch01163 YP_001979554.1 yhch01164 YP_001979555.1 ypch01181 YP_001979556.1 ypch01182 YP_001979557.1 ypch01183 YP_001979558.1 ypch01184 YP_001979561.1 ypch01185 YP_001979562.1 ypch01186 YP_001979563.1 ypch01187 YP_001979564.1 ypch01188 YP_001979565.1 ypch01189 YP_001979566.1 ypch01190 YP_001979567.1 yhch01165 YP_001979568.1 yhch01166 YP_001979569.1 yhch01167 YP_001979570.1 yhch01168 YP_001979571.1 yhch01169 YP_001979572.1 yhch01170 YP_001979573.1 yhch01171 YP_001979574.1 yhch01172 YP_001979575.1 ypch01191 YP_001979576.1 ypch01192 YP_001979581.1 ypch01193 YP_001979582.1 ypch01194 YP_001979583.1 ypch01195 YP_001979584.1 ypch01196 YP_001979585.1 ypch01197 YP_001979589.1 ypch01198 YP_001979592.1 ypch01199 YP_001979597.1 yhch01173 YP_001979599.1 ypch01200 YP_001979602.1 yhch01174 YP_001979604.1 ypch01201 YP_001979605.1 yhch01175 YP_001979606.1 yhch01176 YP_001979607.1 yhch01177 YP_001979608.1 yhch01178 YP_001979609.1 ypch01202 YP_001979610.1 ypch01203 YP_001979611.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001979614.1 yhch01179 YP_001979615.1 ypch01204 YP_001979617.1 yhch01180 YP_001979618.1 yhch01181 YP_001979619.1 ypch01205 YP_001979620.1 ypch01206 YP_001979621.1 ypch01207 YP_001979622.1 ypch01208 YP_001979623.1 ypch01209 YP_001979624.1 yhch01182 YP_001979625.1 yhch01183 YP_001979627.1 ypch01210 YP_001979628.1 ypch01211 YP_001979629.1 ypch01212 YP_001979630.1 yhch01184 YP_001979631.1 ypch01213 YP_001979632.1 yhch01185 YP_001979633.1 yhch01186 YP_001979634.1 ypch01214 YP_001979635.1 yhch01187 YP_001979640.1 with HmuTU is involved in the transport of hemin YP_001979641.1 yhch01188 YP_001979642.1 yhch01189 YP_001979643.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001979644.1 yhch01190 YP_001979645.1 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media YP_001979647.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001979648.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001979649.1 yhch01191 YP_001979650.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism YP_001979651.1 ypch01217 YP_001979652.1 ypch01218 YP_001979653.1 ypch01219 YP_001979656.1 ypch01220 YP_001979657.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001979658.1 yhch01192 YP_001979659.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001979660.1 yhch01193 YP_001979661.1 ypch01221 YP_001979662.1 ypch01222 YP_001979663.1 ypch01223 YP_001979664.1 ypch01224 YP_001979665.1 ypch01225 YP_001979666.1 ypch01226 YP_001979670.1 ypch01227 YP_001979671.1 ypch01228 YP_001979672.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001979673.1 ypch01229 YP_001979674.1 ypch01230 YP_001979675.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_001979676.1 ypch01231 YP_001979677.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_001979679.1 ypch01232 YP_001979680.1 yhch01194 YP_001979681.1 ypch01233 YP_001979682.1 ypch01234 YP_001979683.1 ypch01235 YP_001979684.1 ypch01236 YP_001979685.1 ypch01237 YP_001979686.1 ypch01238 YP_001979687.1 ypch01239 YP_001979689.1 yhch01195 YP_001979694.1 yhch01196 YP_001979697.1 yhch01197 YP_001979698.1 yhch01198 YP_001979699.1 yhch01199 YP_001979700.1 ypch01240 YP_001979701.1 yhch01200 YP_001979703.1 ypch01241 YP_001979704.1 yhch01201 YP_001979705.1 yhch01202 YP_001979706.1 yhch01203 YP_001979707.1 ypch01242 YP_001979708.1 yhch01204 YP_001979710.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001979711.1 yhch01205 YP_001979712.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001979713.1 yhch01206 YP_001979714.1 ypch01243 YP_001979715.1 ypch01244 YP_001979718.1 ypch01246 YP_001979719.1 ypch01247 YP_001979720.1 member of a large family of NAD or NADP-dependent oxidoreductases; paralogs occur in many bacteria YP_001979721.1 ypch01249 YP_001979722.1 yhch01207 YP_001979723.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair YP_001979724.1 ypch01251 YP_001979725.1 ypch01252 YP_001979726.1 ypch01253 YP_001979727.1 ypch01254 YP_001979730.1 ypch01255 YP_001979731.1 ypch01256 YP_001979732.1 ypch01257 YP_001979733.1 ypch01258 YP_001979734.1 ypch01259 YP_001979735.1 yhch01208 YP_001979736.1 yhch01209 YP_001979737.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001979741.1 ypch01260 YP_001979742.1 ypch01261 YP_001979743.1 ypch01262 YP_001979744.1 ypch01263 YP_001979745.1 ypch01264 YP_001979746.1 ypch01265 YP_001979747.1 ypch01266 YP_001979748.1 ypch01267 YP_001979750.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001979751.1 yhch01210 YP_001979752.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport YP_001979756.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001979762.1 yhch01211 YP_001979763.1 ypch01269 YP_001979765.1 yhch01212 YP_001979766.1 yhch01213 YP_001979768.1 Involved in nucleotide synthesis and salvage YP_001979769.1 ypch01271 YP_001979770.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001979771.1 ypch01272 YP_001979772.1 ypch01273 YP_001979773.1 ypch01274 YP_001979775.1 ypch01275 YP_001979783.1 yhch01214 YP_001979784.1 yhch01215 YP_001979785.1 yhch01216 YP_001979786.1 ypch01276 YP_001979787.1 ypch01277 YP_001979788.1 ypch01278 YP_001979789.1 yhch01217 YP_001979790.1 yhch01218 YP_001979791.1 yhch01219 YP_001979792.1 ypch01279 YP_001979793.1 yhch01220 YP_001979794.1 ypch01280 YP_001979795.1 Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation YP_001979797.1 ypch01281 YP_001979799.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_001979800.1 ypch01282 YP_001979801.1 ypch01283 YP_001979802.1 ypch01284 YP_001979803.1 ypch01285 YP_001979804.1 ypch01286 YP_001979806.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001979807.1 yhch01221 YP_001979808.1 yhch01222 YP_001979809.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001979810.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_001979811.1 ypch01287 YP_001979812.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001979814.1 ypch01288 YP_001979815.1 yhch01223 YP_001979817.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001979818.1 yhch01224 YP_001979822.1 ypch01290 YP_001979826.1 ypch01291 YP_001979827.1 ypch01292 YP_001979828.1 yhch01225 YP_001979829.1 yhch01226 YP_001979830.1 yhch01227 YP_001979831.1 ypch01293 YP_001979832.1 ypch01294 YP_001979833.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001979834.1 ypch01295 YP_001979835.1 ypch01296 YP_001979836.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001979837.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001979838.1 ypch01297 YP_001979839.1 ypch01298 YP_001979840.1 yhch01228 YP_001979842.1 yhch01229 YP_001979843.1 yhch01230 YP_001979844.1 ypch01299 YP_001979845.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_001979846.1 yhch01231 YP_001979847.1 ypch01301 YP_001979848.1 yhch01232 YP_001979849.1 ypch01302 YP_001979850.1 yhch01233 YP_001979851.1 yhch01234 YP_001979852.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001979854.1 yhch01235 YP_001979855.1 yhch01236 YP_001979856.1 yhch01237 YP_001979857.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001979858.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001979861.1 yhch01238 YP_001979862.1 ypch01304 YP_001979863.1 yhch01239 YP_001979864.1 yhch01240 YP_001979865.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001979866.1 ypch01305 YP_001979867.1 yhch01241 YP_001979868.1 yhch01242 YP_001979869.1 yhch01243 YP_001979870.1 yhch01244 YP_001979871.1 ypch01306 YP_001979872.1 similar to flagellar motor protein MotB; ypch01307 YP_001979873.1 yhch01245 YP_001979875.1 ypch01308 YP_001979876.1 yhch01246 YP_001979877.1 yhch01247 YP_001979878.1 ypch01309 YP_001979879.1 ypch01310 YP_001979883.1 ypch01311 YP_001979884.1 ypch01312 YP_001979887.1 ypch01313 YP_001979889.1 yhch01248 YP_001979890.1 ypch01314 YP_001979891.1 yhch01249 YP_001979892.1 catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole YP_001979893.1 ypch01315 YP_001979894.1 ypch01316 YP_001979895.1 yhch01250 YP_001979896.1 yhch01251 YP_001979898.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001979899.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001979900.1 yhch01252 YP_001979901.1 ypch01317 YP_001979903.1 ypch01318 YP_001979904.1 ypch01319 YP_001979905.1 ypch01320 YP_001979906.1 yhch01253 YP_001979907.1 yhch01254 YP_001979908.1 ypch01321 YP_001979909.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001979910.1 yhch01255 YP_001979911.1 ypch01322 YP_001979912.1 yhch01256 YP_001979913.1 yhch01257 YP_001979914.1 ypch01323 YP_001979915.1 yhch01258 YP_001979916.1 yhch01259 YP_001979919.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine YP_001979920.1 ypch01324 YP_001979921.1 yhch01260 YP_001979923.1 ypch01325 YP_001979924.1 yhch01261 YP_001979925.1 ypch01326 YP_001979926.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001979927.1 ypch01327 YP_001979928.1 ypch01328 YP_001979930.1 yhch01262 YP_001979932.1 ypch01329 YP_001979933.1 yhch01263 YP_001979934.1 yhch01264 YP_001979935.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001979937.1 yhch01265 YP_001979939.1 ypch01330 YP_001979940.1 ypch01331 YP_001979943.1 ypch01332 YP_001979944.1 yhch01266 YP_001979945.1 yhch01267 YP_001979946.1 yhch01268 YP_001979947.1 yhch01269 YP_001979948.1 yhch01270 YP_001979949.1 yhch01271 YP_001979950.1 yhch01272 YP_001979951.1 yhch01273 YP_001979952.1 yhch01274 YP_001979953.1 ypch01333 YP_001979954.1 ypch01334 YP_001979955.1 yhch01275 YP_001979957.1 yhch01276 YP_001979958.1 yhch01277 YP_001979959.1 yhch01278 YP_001979960.1 yhch01279 YP_001979961.1 yhch01280 YP_001979962.1 yhch01281 YP_001979963.1 yhch01282 YP_001979964.1 yhch01283 YP_001979965.1 yhch01284 YP_001979966.1 ypch01335 YP_001979967.1 yhch01285 YP_001979969.1 ypch01336 YP_001979970.1 ypch01337 YP_001979971.1 ypch01338 YP_001979972.1 yhch01286 YP_001979973.1 ypch01339 YP_001979974.1 yhch01287 YP_001979975.1 yhch01288 YP_001979977.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001979978.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001979979.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001979980.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001979983.1 ypch01340 YP_001979988.1 yhch01289 YP_001979991.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001979992.1 ypch01341 YP_001979993.1 ypch01342 YP_001979994.1 yhch01290 YP_001979998.1 ypch01343 YP_001979999.1 yhch01291 YP_001980000.1 ypch01344 YP_001980001.1 ypch01345 YP_001980002.1 ypch01346 YP_001980003.1 ypch01347 YP_001980004.1 ypch01348 YP_001980005.1 ypch01349 YP_001980006.1 ypch01350 YP_001980007.1 ypch01351 YP_001980008.1 ypch01352 YP_001980009.1 ypch01353 YP_001980010.1 yhch01292 YP_001980012.1 ypch01354 YP_001980013.1 ypch01355 YP_001980014.1 ypch01356 YP_001980015.1 ypch01357 YP_001980016.1 yhch01293 YP_001980017.1 ypch01358 YP_001980018.1 yhch01294 YP_001980019.1 ypch01359 YP_001980020.1 yhch01295 YP_001980021.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001980022.1 ypch01360 YP_001980023.1 ypch01361 YP_001980024.1 ypch01362 YP_001980025.1 ypch01363 YP_001980027.1 yhch01296 YP_001980028.1 ypch01364 YP_001980029.1 ypch01365 YP_001980030.1 ypch01366 YP_001980031.1 ypch01367 YP_001980032.1 ypch01368 YP_001980033.1 ypch01369 YP_001980034.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001980036.1 ypch01370 YP_001980037.1 ypch01371 YP_001980038.1 ypch01372 YP_001980039.1 ypch01373 YP_001980040.1 ypch01374 YP_001980041.1 ypch01375 YP_001980042.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001980043.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001980044.1 yhch01297 YP_001980045.1 ypch01376 YP_001980046.1 ypch01377 YP_001980047.1 ypch01378 YP_001980048.1 ypch01379 YP_001980049.1 ypch01380 YP_001980050.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_001980051.1 yhch01298 YP_001980052.1 yhch01299 YP_001980053.1 yhch01300 YP_001980055.1 yhch01301 YP_001980056.1 ypch01382 YP_001980057.1 yhch01302 YP_001980058.1 ypch01383 YP_001980059.1 yhch01303 YP_001980061.1 ypch01384 YP_001980062.1 ypch01385 YP_001980063.1 role in sulfur assimilation YP_001980064.1 ypch01387 YP_001980066.1 ypch01388 YP_001980073.1 ypch01389 YP_001980074.1 ypch01390 YP_001980076.1 ypch01391 YP_001980077.1 ypch01392 YP_001980078.1 ypch01393 YP_001980080.1 ypch01394 YP_001980081.1 ypch01395 YP_001980082.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001980083.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001980084.1 ypch01397 YP_001980085.1 ypch01398 YP_001980087.1 yhch01304 YP_001980088.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001980090.1 ypch01400 YP_001980091.1 ypch01401 YP_001980092.1 ypch01402 YP_001980093.1 ypch01403 YP_001980095.1 ypch01404 YP_001980096.1 ypch01405 YP_001980097.1 ypch01406 YP_001980098.1 ypch01407 YP_001980103.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001980104.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001980105.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001980107.1 ypch01408 YP_001980108.1 ypch01409 YP_001980109.1 ypch01410 YP_001980111.1 ypch01411 YP_001980112.1 ypch01412 YP_001980113.1 yhch01305 YP_001980114.1 ypch01413 YP_001980115.1 yhch01306 YP_001980116.1 ypch01414 YP_001980117.1 ypch01415 YP_001980118.1 yhch01307 YP_001980119.1 yhch01308 YP_001980120.1 ypch01416 YP_001980121.1 ypch01417 YP_001980122.1 yhch01309 YP_001980123.1 yhch01310 YP_001980124.1 yhch01311 YP_001980125.1 ypch01418 YP_001980126.1 ypch01419 YP_001980127.1 ypch01420 YP_001980128.1 ypch01421 YP_001980129.1 ypch01422 YP_001980131.1 yhch01312 YP_001980133.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001980135.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001980136.1 Involved in ubiquinone biosynthesis YP_001980137.1 yhch01313 YP_001980138.1 ypch01423 YP_001980141.1 ypch01424 YP_001980142.1 ypch01425 YP_001980143.1 yhch01314 YP_001980145.1 ypch01426 YP_001980146.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001980148.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001980149.1 ypch01427 YP_001980150.1 yhch01315 YP_001980152.1 ypch01428 YP_001980153.1 yhch01316 YP_001980154.1 ypch01429 YP_001980155.1 ypch01430 YP_001980156.1 yhch01317 YP_001980157.1 yhch01318 YP_001980158.1 ypch01431 YP_001980159.1 yhch01319 YP_001980160.1 ypch01432 YP_001980161.1 yhch01320 YP_001980162.1 ypch01433 YP_001980164.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001980165.1 ypch01434 YP_001980166.1 ypch01435 YP_001980167.1 yhch01321 YP_001980168.1 ypch01436 YP_001980169.1 ypch01437 YP_001980172.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001980174.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001980175.1 yhch01322 YP_001980177.1 yhch01323 YP_001980178.1 ypch01438 YP_001980180.1 yhch01324 YP_001980183.1 yhch01325 YP_001980186.1 yhch01326 YP_001980187.1 ypch01439 YP_001980188.1 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate YP_001980189.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001980190.1 ypch01440 YP_001980192.1 yhch01327 YP_001980193.1 yhch01328 YP_001980194.1 yhch01329 YP_001980195.1 yhch01330 YP_001980196.1 required for 70S ribosome assembly YP_001980197.1 yhch01331 YP_001980198.1 yhch01332 YP_001980199.1 yhch01333 YP_001980203.1 ypch01441 YP_001980204.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001980205.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001980206.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001980207.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001980208.1 yhch01334 YP_001980209.1 yhch01335 YP_001980210.1 ypch01442 YP_001980212.1 ypch01443 YP_001980213.1 yhch01336 YP_001980214.1 yhch01337 YP_001980215.1 yhch01338 YP_001980216.1 yhch01339 YP_001980217.1 yhch01340 YP_001980218.1 yhch01341 YP_001980219.1 ypch01444 YP_001980220.1 yhch01342 YP_001980221.1 yhch01343 YP_001980222.1 yhch01344 YP_001980223.1 yhch01345 YP_001980224.1 yhch01346 YP_001980225.1 yhch01347 YP_001980226.1 yhch01348 YP_001980227.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001980228.1 ypch01445 YP_001980229.1 yhch01349 YP_001980230.1 ypch01446 YP_001980231.1 ypch01447 YP_001980232.1 ypch01448 YP_001980233.1 ypch01449 YP_001980234.1 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine YP_001980235.1 yhch01350 YP_001980236.1 ypch01450 YP_001980237.1 yhch01351 YP_001980238.1 ypch01451 YP_001980244.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001980247.1 catalyzes the oxidation of formate to carbon dioxide and hydrogen using NAD or NADP as the acceptor YP_001980248.1 ypch01452 YP_001980249.1 ypch01453 YP_001980250.1 ypch01454 YP_001980252.1 ypch01455 YP_001980253.1 ypch01456 YP_001980254.1 ypch01457 YP_001980255.1 ypch01458 YP_001980257.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001980258.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001980259.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001980260.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001980261.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001980262.1 yhch01352 YP_001980263.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001980264.1 ypch01459 YP_001980265.1 ypch01460 YP_001980266.1 ypch01461 YP_001980267.1 ypch01462 YP_001980268.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001980269.1 yhch01353 YP_001980270.1 ypch01463 YP_001980271.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001980272.1 ypch01464 YP_001980273.1 yhch01354 YP_001980274.1 yhch01355 YP_001980275.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001980276.1 yhch01356 YP_001980277.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001980278.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001980279.1 yhch01357 YP_001980280.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001980281.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001980282.1 ypch01465 YP_001980284.1 yhch01358 YP_001980285.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001980286.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001980289.1 yhch01359 YP_001980290.1 ypch01466 YP_001980291.1 yhch01360 YP_001980292.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001980293.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001980294.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001980295.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001980296.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane YP_001980297.1 yhch01362 YP_001980298.1 yhch01363 YP_001980299.1 yhch01364 YP_001980300.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_001980301.1 ypch01467 YP_001980302.1 yhch01365 YP_001980303.1 yhch01366 YP_001980304.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001980305.1 ypch01468 YP_001980308.1 yhch01367 YP_001980309.1 ypch01469 YP_001980310.1 ypch01470 YP_001980311.1 yhch01368 YP_001980312.1 ypch01471 YP_001980313.1 ypch01472 YP_001980314.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001980315.1 ypch01473 YP_001980316.1 ypch01474 YP_001980317.1 ypch01475 YP_001980318.1 ypch01476 YP_001980319.1 ypch01477 YP_001980320.1 yhch01369 YP_001980321.1 yhch01370 YP_001980322.1 ypch01478 YP_001980323.1 yhch01371 YP_001980324.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001980325.1 ypch01479 YP_001980327.1 ypch01480 YP_001980328.1 ypch01481 YP_001980329.1 ypch01482 YP_001980330.1 yhch01372 YP_001980331.1 ypch01483 YP_001980332.1 yhch01373 YP_001980333.1 yhch01374 YP_001980334.1 Catalyzes the conversion of citrate to isocitrate YP_001980335.1 ATP-binding protein; required for proper cytochrome c maturation YP_001980338.1 ypch01484 YP_001980340.1 yhch01375 YP_001980341.1 Involved in cell division; probably involved in intracellular septation YP_001980343.1 ypch01485 YP_001980344.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001980345.1 yhch01376 YP_001980347.1 catalyzes the interconversion of chorismate to prephenate YP_001980348.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001980349.1 Essential for efficient processing of 16S rRNA YP_001980350.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001980351.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001980352.1 ypch01486 YP_001980353.1 ypch01487 YP_001980354.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001980355.1 ypch01488 YP_001980356.1 ypch01489 YP_001980357.1 yhch01377 YP_001980358.1 ypch01490 YP_001980359.1 ypch01491 YP_001980361.1 ypch01492 YP_001980366.1 ypch01493 YP_001980367.1 yhch01378 YP_001980370.1 yhch01379 YP_001980371.1 yhch01380 YP_001980372.1 yhch01381 YP_001980373.1 yhch01382 YP_001980374.1 ypch01494 YP_001980375.1 yhch01383 YP_001980378.1 yhch01384 YP_001980380.1 ypch01495 YP_001980381.1 ypch01496 YP_001980382.1 ypch01497 YP_001980388.1 yhch01385 YP_001980389.1 yhch01386 YP_001980391.1 ypch01498 YP_001980392.1 ypch01499 YP_001980393.1 responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA YP_001980394.1 yhch01387 YP_001980395.1 ypch01500 YP_001980396.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_001980397.1 ypch01501 YP_001980398.1 ypch01502 YP_001980399.1 ypch01503 YP_001980400.1 ypch01504 YP_001980401.1 ypch01505 YP_001980402.1 ypch01506 YP_001980403.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001980404.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001980406.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001980407.1 yhch01388 YP_001980409.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001980410.1 yhch01389 YP_001980412.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001980414.1 yhch01390 YP_001980415.1 yhch01391 YP_001980416.1 ypch01507 YP_001980417.1 ypch01508 YP_001980419.1 ypch01509 YP_001980420.1 yhch01392 YP_001980421.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production YP_001980422.1 ypch01510 YP_001980423.1 ypch01511 YP_001980424.1 ypch01512 YP_001980425.1 ypch01513 YP_001980426.1 ypch01514 YP_001980427.1 ypch01515 YP_001980428.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001980430.1 ypch01516 YP_001980433.1 yhch01393 YP_001980434.1 yhch01394 YP_001980435.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001980438.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_001980440.1 ypch01517 YP_001980442.1 ypch01518 YP_001980443.1 ypch01519 YP_001980445.1 ypch01520 YP_001980446.1 ypch01521 YP_001980447.1 yhch01396 YP_001980448.1 ypch01522 YP_001980449.1 ypch01523 YP_001980453.1 yhch01397 YP_001980454.1 yhch01398 YP_001980455.1 yhch01399 YP_001980457.1 involved in the peptidyltransferase reaction during translation YP_001980458.1 ypch01524 YP_001980459.1 ypch01525 YP_001980460.1 ypch01526 YP_001980461.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001980462.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001980463.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001980464.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001980465.1 yhch01400 YP_001980467.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001980470.1 yhch01401 YP_001980471.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001980472.1 ypch01528 YP_001980474.1 yhch01403 YP_001980475.1 hydrolyzes diadenosine polyphosphate YP_001980477.1 yhch01404 YP_001980479.1 ypch01529 YP_001980480.1 yhch01405 YP_001980481.1 yhch01406 YP_001980482.1 yhch01407 YP_001980484.1 yhch01408 YP_001980485.1 yhch01409 YP_001980486.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001980487.1 ypch01530 YP_001980488.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001980489.1 ypch01531 YP_001980490.1 ypch01532 YP_001980491.1 yhch01410 YP_001980492.1 ypch01533 YP_001980493.1 yhch01411 YP_001980495.1 yhch01412 YP_001980496.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001980497.1 ypch01534 YP_001980498.1 ypch01535 YP_001980500.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001980501.1 yhch01413 YP_001980502.1 ypch01536 YP_001980503.1 ypch01537 YP_001980504.1 involved in de novo purine biosynthesis YP_001980505.1 yhch01414 YP_001980506.1 ypch01538 YP_001980507.1 metalloprotease YP_001980508.1 yhch01415 YP_001980509.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001980510.1 yhch01416 YP_001980512.1 ypch01539 YP_001980513.1 ypch01540 YP_001980514.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001980515.1 yhch01417 YP_001980516.1 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA YP_001980519.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001980520.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001980521.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001980522.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001980523.1 yhch01418 YP_001980524.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001984278.1 yhb00001 YP_001984279.1 yhb00002 YP_001984280.1 yhb00003 YP_001984282.1 yhb00004 YP_001984283.1 yhb00006 YP_001984284.1 yhb00007 YP_001984285.1 ypb00001 YP_001984286.1 ypb00002 YP_001984287.1 yhb00008 YP_001984288.1 ypb00003 YP_001984289.1 ypb00004 YP_001984290.1 ypb00005 YP_001984291.1 yhb00010 YP_001984292.1 yhb00011 YP_001984293.1 yhb00012 YP_001984294.1 yhb00013 YP_001984295.1 ypb00006 YP_001984296.1 ypb00007 YP_001984297.1 yhb00014 YP_001984298.1 yhb00015 YP_001984299.1 yhb00016 YP_001984300.1 yhb00017 YP_001984301.1 ypb00008 YP_001984302.1 ypb00009 YP_001984303.1 yhb00018 YP_001984304.1 yhb00019 YP_001984305.1 yhb00020 YP_001984306.1 yhb00023 YP_001984307.1 ypb00011 YP_001984308.1 yhb00024 YP_001984309.1 yhb00025 YP_001984310.1 ypb00012 YP_001984312.1 yhb00027 YP_001984313.1 yhb00028 YP_001984314.1 ypb00014 YP_001984315.1 yhb00029 YP_001984316.1 yhb00030 YP_001984317.1 ypb00015 YP_001984318.1 ypb00016 YP_001984319.1 ypb00017 YP_001984320.1 yhb00031 YP_001984321.1 yhb00032 YP_001984322.1 yhb00033 YP_001984323.1 ypb00019 YP_001984324.1 ypb00020 YP_001984325.1 ypb00021 YP_001984326.1 yhb00034 YP_001984327.1 yhb00035 YP_001984329.1 N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid YP_001984330.1 ypb00024 YP_001984331.1 ypb00025 YP_001984332.1 ypb00026 YP_001984333.1 ypb00027 YP_001984334.1 ypb00028 YP_001984335.1 yhb00036 YP_001984336.1 yhb00037 YP_001984337.1 yhb00038 YP_001984338.1 yhb00039 YP_001984339.1 ypb00030 YP_001984340.1 yhb00041 YP_001984341.1 yhb00042 YP_001984342.1 yhb00043 YP_001984343.1 yhb00046 YP_001984344.1 yhb00047 YP_001984345.1 yhb00048 YP_001984346.1 yhb00049 YP_001984347.1 yhb00050 YP_001984348.1 yhb00051 YP_001984350.1 yhb00052 YP_001984354.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_001984359.1 yhb00053 YP_001984360.1 yhb00054 YP_001984361.1 yhb00055 YP_001984362.1 ypb00032 YP_001984363.1 yhb00056 YP_001984364.1 yhb00057 YP_001984365.1 yhb00058 YP_001984366.1 yhb00059 YP_001984367.1 yhb00060 YP_001984368.1 yhb00061 YP_001984369.1 yhb00062 YP_001984370.1 ypb00033 YP_001984371.1 ypb00034 YP_001984373.1 yhb00063 YP_001984374.1 ypb00035 YP_001984380.1 yhb00064 YP_001984381.1 yhb00065 YP_001984383.1 yhb00066 YP_001984384.1 ypb00036 YP_001984385.1 ypb00037 YP_001984387.1 ypb00038 YP_001984388.1 ypb00039 YP_001984389.1 yhb00067 YP_001984390.1 ypb00040 YP_001984392.1 yhb00068 YP_001984393.1 ypb00041 YP_001984394.1 ypb00042 YP_001984395.1 ypb00043 YP_001984396.1 ypb00044 YP_001984398.1 ypb00045 YP_001984399.1 ypb00046 YP_001984401.1 ypb00047 YP_001984402.1 ypb00048 YP_001984404.1 ypb00049 YP_001984410.1 ypb00050 YP_001984411.1 yhb00069 YP_001984413.1 ypb00051 YP_001984415.1 ypb00052 YP_001984416.1 ypb00053 YP_001984417.1 ypb00054 YP_001984418.1 yhb00070 YP_001984419.1 yhb00071 YP_001984420.1 yhb00072 YP_001984426.1 yhb00073 YP_001984433.1 yhb00074 YP_001984434.1 ypb00055 YP_001984435.1 yhb00075 YP_001984436.1 yhb00076 YP_001984437.1 yhb00077 YP_001984438.1 yhb00078 YP_001984439.1 yhb00080 YP_001984440.1 yhb00081 YP_001984441.1 yhb00082 YP_001984442.1 yhb00083 YP_001984443.1 yhb00084 YP_001984444.1 yhb00085 YP_001984445.1 VirD4 family YP_001984449.1 yhb00086 YP_001984450.1 yhb00087 YP_001984451.1 yhb00088 YP_001984452.1 ypb00057 YP_001984453.1 yhb00089 YP_001984454.1 ypb00058 YP_001984455.1 yhb00090 YP_001984460.1 yhb00091 YP_001984461.1 yhb00092 YP_001984462.1 yhb00093 YP_001984463.1 yhb00094 YP_001984464.1 yhb00095 YP_001984465.1 yhb00096 YP_001984466.1 yhb00097 YP_001984467.1 yhb00098 YP_001984468.1 yhb00099 YP_001984469.1 yhb00100 YP_001984470.1 yhb00101 YP_001984471.1 yhb00102 YP_001984472.1 yhb00103 YP_001984473.1 yhb00104 YP_001984474.1 yhb00105 YP_001984475.1 yhb00106 YP_001984476.1 yhb00107 YP_001984477.1 yhb00108 YP_001984478.1 yhb00109 YP_001984479.1 yhb00110 YP_001984480.1 yhb00111 YP_001984481.1 yhb00112 YP_001984482.1 yhb00113 YP_001984483.1 yhb00115 YP_001984484.1 yhb00116 YP_001984485.1 yhb00117 YP_001984486.1 yhb00118 YP_001984487.1 yhb00119 YP_001984488.1 yhb00120 YP_001984489.1 yhb00121 YP_001984490.1 yhb00122 YP_001984492.1 ypb00060 YP_001984493.1 ypb00061 YP_001984494.1 yhb00123 YP_001984495.1 yhb00124 YP_001984496.1 yhb00125 YP_001984497.1 yhb00126 YP_001984498.1 ypb00062; fusion protein: integrase catalytic region (Atu4604) and hypothetical conserved protein (brl1705) YP_001984499.1 yhb00127 YP_001984500.1 yhb00128 YP_001984501.1 yhb00129 YP_001984502.1 yhb00130 YP_001984503.1 yhb00131 YP_001984504.1 yhb00132 YP_001984505.1 ypb00063 YP_001984506.1 ypb00064 YP_001984507.1 yhb00133 YP_001984508.1 yhb00134 YP_001984509.1 yhb00135 YP_001984511.1 functions with NifE to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe YP_001984512.1 functions with NifN to assemble FeMo cofactor; functions in assembly of nitrogenase MoFe YP_001984515.1 nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex; in R. etli there are three essentially identical copies of nifH which are actively expressed during symbiosis YP_001984516.1 yhb00136 YP_001984517.1 ypb00065 YP_001984520.1 ypb00066 YP_001984521.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001984522.1 yhb00137 YP_001984525.1 associates with NifD and may protect the nitrogenase Fe-Mo protein from oxidative damage YP_001984534.1 yhb00138 YP_001984535.1 yhb00139 YP_001984537.1 yhb00140 YP_001984538.1 yhb00141 YP_001984539.1 yhb00142 YP_001984540.1 yhb00143 YP_001984542.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_001984543.1 yhb00144 YP_001984544.1 yhb00145 YP_001984546.1 ypb00069 YP_001984549.1 ypb00070 YP_001984550.1 yhb00146 YP_001984552.1 yhb00147 YP_001984554.1 yhb00148 YP_001984555.1 yhb00149 YP_001984557.1 nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex; in R. etli there are three essentially identical copies of nifH which are actively expressed during symbiosis YP_001984559.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001984560.1 yhb00150 YP_001984561.1 yhb00151 YP_001984562.1 yhb00152 YP_001984563.1 yhb00153 YP_001984564.1 yhb00154 YP_001984568.1 yhb00155 YP_001984570.1 ATP-binding subunit; with NodJ is involved in the export of lipo-chitin oligosaccharide; involved in nodulation induction YP_001984574.1 yhb00156 YP_001984575.1 yhb00157 YP_001984576.1 yhb00158 YP_001984577.1 ypb00071 YP_001984584.1 CcoO; FixO YP_001984585.1 CcoN; FixN YP_001984587.1 yhb00159 YP_001984588.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001984589.1 yhb00160 YP_001984591.1 yhb00161 YP_001984592.1 yhb00162 YP_001984594.1 yhb00163 YP_001984595.1 yhb00164 YP_001984596.1 ypb00072 YP_001984599.1 nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex; in R. etli there are three essentially identical copies of nifH which are actively expressed during symbiosis YP_001984600.1 yhb00165 YP_001984601.1 catalyzes the transfer of a fatty acyl group onto Nod factor, beta-(1,4)-N-acetylglucosamine oligosaccharide YP_001984602.1 yhb00166 YP_001984603.1 yhb00167 YP_001984604.1 yhb00168 YP_001984605.1 yhb00169 YP_001984606.1 ypb00074 YP_001984607.1 yhb00170 YP_001984608.1 ypb00075 YP_001984611.1 yhb00171 YP_001984613.1 ypb00076 YP_001984614.1 yhb00172 YP_001984615.1 yhb00173 YP_001984616.1 yhb00174 YP_001984617.1 ypb00077 YP_001984618.1 ypb00078 YP_001984619.1 yhb00175 YP_001984620.1 yhb00176 YP_001984621.1 yhb00177 YP_001984622.1 ypb00079 YP_001984623.1 yhb00178 YP_001984624.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001984625.1 ypb00080 YP_001984626.1 yhb00179 YP_001984627.1 yhb00180 YP_001984628.1 yhb00181 YP_001984630.1 ypb00081 YP_001984634.1 ypc00001 YP_001984635.1 ypc00002 YP_001984636.1 yhc00001 YP_001984637.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001984638.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001984641.1 yhc00002 YP_001984643.1 yhc00003 YP_001984644.1 ypc00003 YP_001984645.1 ypc00004 YP_001984646.1 ypc00005 YP_001984647.1 yhc00004 YP_001984648.1 ypc00006 YP_001984649.1 ypc00007 YP_001984650.1 ypc00008 YP_001984651.1 ypc00009 YP_001984653.1 ypc00010 YP_001984654.1 yhc00005 YP_001984655.1 yhc00006 YP_001984656.1 yhc00007 YP_001984657.1 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine YP_001984658.1 ypc00011 YP_001984659.1 yhc00008 YP_001984660.1 ypc00012 YP_001984661.1 yhc00009 YP_001984662.1 yhc00010 YP_001984663.1 yhc00011 YP_001984664.1 ypc00013 YP_001984665.1 yhc00012 YP_001984667.1 ypc00014 YP_001984668.1 ypc00015 YP_001984669.1 ypc00016 YP_001984671.1 yhc00013 YP_001984672.1 ypc00017 YP_001984673.1 yhc00014 YP_001984674.1 yhc00016 YP_001984675.1 ypc00018 YP_001984676.1 yhc00017 YP_001984677.1 ypc00019 YP_001984678.1 ypc00020 YP_001984679.1 ypc00021 YP_001984680.1 yhc00018 YP_001984681.1 yhc00019 YP_001984682.1 yhc00020 YP_001984683.1 yhc00021 YP_001984684.1 yhc00022 YP_001984685.1 yhc00023 YP_001984686.1 yhc00024 YP_001984687.1 ypc00023 YP_001984688.1 ypc00024 YP_001984689.1 ypc00025 YP_001984690.1 ypc00026 YP_001984691.1 ypc00027 YP_001984692.1 ypc00028 YP_001984693.1 ypc00029 YP_001984694.1 ypc00030 YP_001984695.1 ypc00031 YP_001984696.1 yhc00025 YP_001984697.1 ypc00032 YP_001984698.1 ypc00033 YP_001984699.1 ypc00034 YP_001984700.1 yhc00026 YP_001984701.1 yhc00027 YP_001984702.1 yhc00028 YP_001984703.1 ypc00035 YP_001984704.1 yhc00029 YP_001984705.1 ypc00036 YP_001984706.1 ypc00037 YP_001984707.1 ypc00038 YP_001984708.1 yhc00030 YP_001984709.1 ypc00039 YP_001984710.1 ypc00040 YP_001984711.1 ypc00041 YP_001984712.1 yhc00031 YP_001984713.1 ypc00042 YP_001984714.1 yhc00032 YP_001984715.1 yhc00033 YP_001984716.1 ypc00043 YP_001984717.1 ypc00044 YP_001984718.1 ypc00045 YP_001984719.1 ypc00046 YP_001984720.1 ypc00047 YP_001984721.1 ypc00048 YP_001984722.1 ypc00049 YP_001984723.1 ypc00050 YP_001984724.1 ypc00051 YP_001984725.1 ypc00052 YP_001984726.1 ypc00053 YP_001984727.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001984728.1 ypc00054 YP_001984729.1 ypc00055 YP_001984730.1 ypc00056 YP_001984731.1 ypc00057 YP_001984732.1 ypc00058 YP_001984733.1 ypc00059 YP_001984734.1 ypc00060 YP_001984735.1 yhc00034 YP_001984736.1 yhc00035 YP_001984737.1 ypc00061 YP_001984738.1 ypc00062 YP_001984739.1 ypc00063 YP_001984741.1 ypc00064 YP_001984742.1 ypc00065 YP_001984743.1 yhc00036 YP_001984744.1 ypc00066 YP_001984745.1 ypc00067 YP_001984746.1 yhc00037 YP_001984747.1 ypc00068 YP_001984748.1 ypc00069 YP_001984749.1 ypc00070 YP_001984750.1 ypc00071 YP_001984751.1 ypc00072 YP_001984752.1 ypc00073 YP_001984753.1 yhc00038 YP_001984754.1 ypc00074 YP_001984755.1 ypc00075 YP_001984756.1 ypc00076 YP_001984757.1 yhc00039 YP_001984759.1 ypc00077 YP_001984760.1 ypc00078 YP_001984761.1 ypc00079 YP_001984762.1 ypc00080 YP_001984763.1 ypc00081 YP_001984764.1 ypc00082 YP_001984765.1 yhc00040 YP_001984766.1 yhc00041 YP_001984767.1 yhc00042 YP_001984768.1 ypc00083 YP_001984769.1 ypc00084 YP_001984770.1 ypc00085 YP_001984771.1 yhc00043 YP_001984772.1 yhc00044 YP_001984773.1 yhc00045 YP_001984775.1 ypc00086 YP_001984776.1 ypc00087 YP_001984777.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001984778.1 yhc00046 YP_001984779.1 yhc00047 YP_001984780.1 ypc00088 YP_001984781.1 yhc00048 YP_001984782.1 ypc00089 YP_001984783.1 yhc00049 YP_001984784.1 ypc00090 YP_001984785.1 ypc00091 YP_001984786.1 yhc00050 YP_001984787.1 yhc00051 YP_001984788.1 ypc00092 YP_001984789.1 ypc00093 YP_001984790.1 ypc00094 YP_001984791.1 ypc00095 YP_001984792.1 ypc00096 YP_001984793.1 ypc00097 YP_001984794.1 MDM; functions in conversion of succinate to propionate YP_001984795.1 yhc00052 YP_001984796.1 ypc00098 YP_001984797.1 ypc00099 YP_001984798.1 ypc00100 YP_001984799.1 ypc00101 YP_001984800.1 ypc00102 YP_001984801.1 ypc00103 YP_001984802.1 ypc00104 YP_001984803.1 ypc00105 YP_001984804.1 ypc00106 YP_001984807.1 ypc00107 YP_001984808.1 ypc00108 YP_001984809.1 ypc00109 YP_001984810.1 ypc00110 YP_001984811.1 yhc00053 YP_001984812.1 ypc00111 YP_001984813.1 ypc00112 YP_001984814.1 yhc00054 YP_001984815.1 ypc00113 YP_001984816.1 ypc00114 YP_001984817.1 ypc00115 YP_001984818.1 ypc00116 YP_001984819.1 ypc00117 YP_001984820.1 ypc00118 YP_001984821.1 ypc00119 YP_001984822.1 yhc00055 YP_001984823.1 ypc00120 YP_001984824.1 ypc00121 YP_001984825.1 ypc00122 YP_001984826.1 ypc00123 YP_001984827.1 ypc00124 YP_001984828.1 ypc00125 YP_001984829.1 ypc00126 YP_001984830.1 ypc00127 YP_001984831.1 ypc00128 YP_001984832.1 ypc00129 YP_001984833.1 ypc00130 YP_001984834.1 ypc00131 YP_001984835.1 ypc00132 YP_001984837.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001984838.1 ypc00133 YP_001984839.1 ypc00134 YP_001984840.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001984841.1 ypc00135 YP_001984842.1 ypc00136 YP_001984843.1 ypc00137 YP_001984844.1 ypc00138 YP_001984845.1 ypc00139 YP_001984846.1 yhc00056 YP_001984848.1 ypc00140 YP_001984850.1 yhc00057 YP_001984851.1 ypc00141 YP_001984852.1 ypc00142 YP_001984853.1 ypc00143 YP_001984854.1 yhc00058 YP_001984855.1 yhc00059 YP_001984856.1 ypc00144 YP_001984857.1 ypc00145 YP_001984858.1 ypc00146 YP_001984859.1 ypc00147 YP_001984860.1 ypc00148 YP_001984861.1 yhc00060 YP_001984862.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli YP_001984863.1 ypc00150 YP_001984864.1 ypc00151 YP_001984865.1 ypc00152 YP_001984866.1 ypc00153 YP_001984868.1 ypc00154 YP_001984870.1 ypc00155 YP_001984871.1 yhc00061 YP_001984872.1 ypc00156 YP_001984873.1 yhc00062 YP_001984874.1 ypc00157 YP_001984875.1 yhc00063 YP_001984876.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001984878.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001984879.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_001984880.1 yhc00065 YP_001984881.1 ypc00158 YP_001984882.1 ypc00159 YP_001984883.1 ypc00160 YP_001984884.1 yhc00066 YP_001984885.1 ypc00161 YP_001984886.1 yhc00067 YP_001984887.1 ypc00162 YP_001984888.1 yhc00068 YP_001984889.1 ypc00163 YP_001984890.1 ypc00164 YP_001984891.1 ypc00165 YP_001984892.1 ypc00166 YP_001984893.1 ypc00167 YP_001984894.1 ypc00168 YP_001984895.1 ypc00169 YP_001984896.1 ypc00170 YP_001984897.1 ypc00171 YP_001984898.1 ypc00172 YP_001984899.1 ypc00173 YP_001984900.1 ypc00174 YP_001984901.1 ypc00175 YP_001984902.1 ypc00176 YP_001984903.1 yhc00069 YP_001984905.1 ypc00177 YP_001984906.1 ypc00178 YP_001984907.1 ypc00179 YP_001984908.1 ypc00180 YP_001984910.1 yhc00070 YP_001984911.1 ypc00181 YP_001984912.1 ypc00182 YP_001984913.1 ypc00183 YP_001984914.1 ypc00184 YP_001984915.1 ypc00185 YP_001984916.1 yhc00071 YP_001984917.1 ypc00186 YP_001984918.1 ypc00187 YP_001984919.1 ypc00188 YP_001984921.1 yhc00072 YP_001984922.1 yhc00073 YP_001984923.1 yhc00074 YP_001984924.1 ypc00189 YP_001984925.1 ypc00190 YP_001984926.1 ypc00191 YP_001984927.1 ypc00192 YP_001984928.1 ypc00193 YP_001984929.1 yhc00075 YP_001984930.1 yhc00076 YP_001984931.1 ypc00194 YP_001984932.1 yhc00077 YP_001984933.1 ypc00195 YP_001984934.1 ypc00196 YP_001984935.1 yhc00078 YP_001984936.1 yhc00079 YP_001984937.1 ypc00197 YP_001984938.1 ypc00198 YP_001984939.1 yhc00080 YP_001984940.1 ypc00199 YP_001984941.1 yhc00081 YP_001984942.1 yhc00082 YP_001984943.1 ypc00200 YP_001984944.1 ypc00201 YP_001984945.1 yhc00083 YP_001984946.1 ypc00202 YP_001984947.1 ypc00203 YP_001984948.1 ypc00204 YP_001984949.1 ypc00205 YP_001984950.1 ypc00206 YP_001984952.1 ypc00207 YP_001984953.1 ypc00208 YP_001984956.1 ypc00209 YP_001984957.1 yhc00084 YP_001984958.1 ypc00210 YP_001984959.1 ypc00211 YP_001984960.1 ypc00212 YP_001984961.1 ypc00213 YP_001984962.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001984963.1 ypc00214 YP_001984964.1 yhc00085 YP_001984965.1 ypc00215 YP_001984966.1 yhc00086 YP_001984967.1 yhc00087 YP_001984968.1 ypc00216 YP_001984969.1 yhc00088 YP_001984970.1 ypc00217 YP_001984974.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001984975.1 ypc00218 YP_001984976.1 yhc00089 YP_001984977.1 yhc00090 YP_001984978.1 ypc00219 YP_001984981.1 ypc00220 YP_001984982.1 yhc00091 YP_001984983.1 yhc00092 YP_001984984.1 yhc00093 YP_001984985.1 ypc00221 YP_001984986.1 yhc00094 YP_001984987.1 ypc00222 YP_001984988.1 yhc00095 YP_001984989.1 ypc00223 YP_001984990.1 ypc00224 YP_001984991.1 ypc00225 YP_001984992.1 ypc00226 YP_001984993.1 ypc00227 YP_001984994.1 ypc00228 YP_001984995.1 ypc00229 YP_001984996.1 ypc00230 YP_001984997.1 yhc00096 YP_001984999.1 yhc00097 YP_001985000.1 ypc00233 YP_001985001.1 ypc00234 YP_001985002.1 ypc00235 YP_001985003.1 putative cyclodeaminase YP_001985004.1 catalyzes the formation of 2-oxobutanoate from L-threonine; involved in ectoine utilization YP_001985005.1 ypc00237 YP_001985006.1 ypc00238 YP_001985007.1 ypc00239 YP_001985008.1 ypc00240 YP_001985009.1 ypc00241 YP_001985010.1 ypc00242 YP_001985011.1 ypc00243 YP_001985012.1 ypc00244 YP_001985013.1 ypc00245 YP_001985014.1 ypc00246 YP_001985016.1 ypc00247 YP_001985017.1 ypc00248 YP_001985018.1 ypc00249 YP_001985019.1 ypc00250 YP_001985020.1 yhc00098 YP_001985021.1 yhc00099 YP_001985022.1 ypc00251 YP_001985023.1 ypc00252 YP_001985024.1 ypc00253 YP_001985025.1 yhc00100 YP_001985036.1 yhc00101 YP_001985037.1 yhc00102 YP_001985038.1 yhc00103 YP_001985039.1 ypc00254 YP_001985041.1 ypc00255 YP_001985042.1 ypc00256 YP_001985044.1 ypc00257 YP_001985045.1 ypc00258 YP_001985046.1 ypc00259 YP_001985047.1 ypc00260 YP_001985048.1 ypc00261 YP_001985049.1 ypc00262 YP_001985050.1 ypc00263 YP_001985051.1 ypc00264 YP_001985052.1 ypc00265 YP_001985053.1 ypc00266 YP_001985054.1 ypc00267 YP_001985061.1 yhc00104 YP_001985062.1 yhc00105 YP_001985063.1 yhc00106 YP_001985064.1 ypc00268 YP_001985065.1 yhc00107 YP_001985066.1 ypc00269 YP_001985068.1 yhc00108 YP_001985069.1 yhc00109 YP_001985070.1 ypc00270 YP_001985073.1 ypc00271 YP_001985074.1 yhc00110 YP_001985075.1 yhc00111 YP_001985076.1 yhc00112 YP_001985077.1 yhc00113 YP_001985078.1 yhc00114 YP_001985079.1 yhc00115 YP_001985080.1 yhc00116 YP_001985081.1 yhc00117 YP_001985082.1 yhc00118 YP_001985084.1 ypc00272 YP_001985085.1 ypc00273 YP_001985086.1 ypc00274 YP_001985087.1 yhc00119 YP_001985088.1 yhc00120 YP_001985089.1 ypc00275 YP_001985090.1 ypc00276 YP_001985091.1 ypc00277 YP_001985092.1 ypc00278 YP_001985093.1 ypc00279 YP_001985094.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001985096.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001985097.1 ypc00281 YP_001985098.1 ypc00282 YP_001985099.1 yhc00121 YP_001985100.1 yhc00122 YP_001985101.1 yhc00123 YP_001985102.1 ypc00283 YP_001985103.1 ypc00284 YP_001985105.1 yhc00124 YP_001985106.1 ypc00285 YP_001985107.1 ypc00286 YP_001985108.1 yhc00125 YP_001985109.1 ypc00287 YP_001985110.1 ypc00288 YP_001985111.1 ypc00289 YP_001985112.1 ypc00290 YP_001985113.1 ypc00291 YP_001985114.1 ypc00292 YP_001985115.1 ypc00293 YP_001985116.1 ypc00294 YP_001985117.1 ypc00295 YP_001985118.1 ypc00296 YP_001985119.1 ypc00297 YP_001985120.1 ypc00298 YP_001985121.1 yhc00126 YP_001985122.1 ypc00299 YP_001985123.1 yhc00127 YP_001985124.1 yhc00128 YP_001985127.1 ypc00300 YP_001985128.1 ypc00301 YP_001985129.1 ypc00302 YP_001985130.1 ypc00303 YP_001985131.1 ypc00304 YP_001985132.1 ypc00305 YP_001985133.1 yhc00129 YP_001985134.1 ypc00306 YP_001985135.1 ypc00307 YP_001985136.1 ypc00308 YP_001985137.1 ypc00309 YP_001985138.1 ypc00310 YP_001985139.1 ypc00311 YP_001985140.1 yhc00130 YP_001985141.1 yhc00131 YP_001985142.1 ypc00312 YP_001985143.1 ypc00313 YP_001985144.1 ypc00314 YP_001985145.1 ypc00315 YP_001985146.1 yhc00132 YP_001985147.1 ypc00316 YP_001985148.1 yhc00133 YP_001985149.1 ypc00317 YP_001985150.1 ypc00318 YP_001985151.1 yhc00134 YP_001985152.1 yhc00135 YP_001985153.1 yhc00136 YP_001985154.1 yhc00137 YP_001985155.1 yhc00138 YP_001985156.1 yhc00139 YP_001985158.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; the rhizobia and the high GC gram-positive bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the S. meliloti protein in this cluster is associated with a groES gene and is required for regulation of the early genes involved in nodular formation YP_001985159.1 yhc00140 YP_001985160.1 ypc00319 YP_001985161.1 yhc00141 YP_001985162.1 ypc00320 YP_001985163.1 yhc00142 YP_001985164.1 yhc00143 YP_001985165.1 yhc00144 YP_001985166.1 ypc00321 YP_001985167.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_001985168.1 ypc00322 YP_001985169.1 yhc00145 YP_001985170.1 ypc00323 YP_001985171.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001985173.1 ypc00325 YP_001985174.1 ypc00326 YP_001985175.1 ypc00327 YP_001985176.1 ypc00328 YP_001985177.1 ypc00329 YP_001985178.1 ypc00330 YP_001985179.1 ypc00331 YP_001985180.1 yhc00146 YP_001985181.1 ypc00332 YP_001985182.1 ypc00333 YP_001985183.1 ypc00334 YP_001985184.1 ypc00335 YP_001985185.1 ypc00336 YP_001985186.1 ypc00337 YP_001985187.1 ypc00338 YP_001985188.1 ypc00339 YP_001985189.1 ypc00340 YP_001985191.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain YP_001985192.1 yhc00147 YP_001985194.1 ypc00341 YP_001985195.1 ypc00342 YP_001985196.1 ypc00343 YP_001985197.1 ypc00344 YP_001985198.1 ypc00345 YP_001985199.1 ypc00346 YP_001985200.1 ypc00347 YP_001985201.1 ypc00348 YP_001985202.1 ypc00349 YP_001985203.1 ypc00350 YP_001985204.1 ypc00351 YP_001985205.1 ypc00352 YP_001985208.1 ypc00353 YP_001985209.1 yhc00148 YP_001985210.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_001985211.1 ypc00355 YP_001985213.1 yhc00149 YP_001985216.1 ypc00356 YP_001985218.1 ypc00357 YP_001985219.1 ypc00358 YP_001985220.1 ypc00359 YP_001985221.1 ypc00360 YP_001985222.1 ypc00361 YP_001985223.1 yhc00150 YP_001985224.1 yhc00151 YP_001985225.1 ypc00362 YP_001985226.1 yhc00152 YP_001985227.1 ypc00363 YP_001985228.1 ypc00364 YP_001985229.1 ypc00365 YP_001985230.1 yhc00153 YP_001985231.1 yhc00154 YP_001985232.1 molecular chaperone YP_001985233.1 yhc00155 YP_001985234.1 yhc00156 YP_001985235.1 ypc00366 YP_001985236.1 yhc00157 YP_001985237.1 ypc00367 YP_001985238.1 yhc00158 YP_001985239.1 yhc00159 YP_001985240.1 yhc00160 YP_001985241.1 ypc00368 YP_001985242.1 member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001985243.1 ypc00370 YP_001985244.1 ypc00371 YP_001985247.1 ypc00372 YP_001985248.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001985249.1 ypc00373 YP_001985250.1 ypc00374 YP_001985251.1 ypc00375 YP_001985252.1 ypc00376 YP_001985253.1 ypc00377 YP_001985254.1 yhc00161 YP_001985255.1 yhc00162 YP_001985256.1 yhc00163 YP_001985257.1 yhc00164 YP_001985258.1 yhc00165 YP_001985259.1 ypc00379 YP_001985260.1 ypc00380 YP_001985261.1 yhc00166 YP_001985262.1 yhc00167 YP_001985263.1 yhc00168 YP_001985264.1 yhc00169 YP_001985265.1 yhc00170 YP_001985266.1 ypc00381 YP_001985267.1 ypc00382 YP_001985268.1 ypc00383 YP_001985269.1 ypc00384 YP_001985270.1 ypc00385 YP_001985271.1 ypc00386 YP_001985272.1 ypc00387 YP_001985273.1 ypc00388 YP_001985274.1 ypc00389 YP_001985275.1 ypc00390 YP_001985276.1 ypc00391 YP_001985277.1 ypc00392 YP_001985278.1 ypc00393 YP_001985279.1 ypc00394 YP_001985280.1 ypc00395 YP_001985281.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001985282.1 yhc00171 YP_001985283.1 ypc00397 YP_001985284.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001985285.1 ypc00399 YP_001985286.1 catalyzes the oxidative deamination of D-amino acids YP_001985291.1 yhc00172 YP_001985292.1 ypc00400 YP_001985293.1 ypc00401 YP_001985294.1 yhc00173 YP_001985295.1 yhc00174 YP_001985296.1 ypc00402 YP_001985297.1 ypc00403 YP_001985298.1 ypc00404 YP_001985299.1 ypc00405 YP_001985300.1 ypc00406 YP_001985301.1 yhc00175 YP_001985303.1 yhc00176 YP_001985317.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001985318.1 ypc00407 YP_001985319.1 ypc00408 YP_001985322.1 yhc00177 YP_001985323.1 ypc00409 YP_001985324.1 ypc00410 YP_001985326.1 ypc00411 YP_001985327.1 yhc00178 YP_001985328.1 ypc00412 YP_001985329.1 ypc00413 YP_001985330.1 ypc00414 YP_001985331.1 ypc00415 YP_001985332.1 ypc00416 YP_001985333.1 ypc00417 YP_001985334.1 ypc00418 YP_001985335.1 ypc00419 YP_001985336.1 ypc00420 YP_001985337.1 yhc00179 YP_001985338.1 yhc00180 YP_001985339.1 yhc00181 YP_001985340.1 yhc00182 YP_001985341.1 yhc00183 YP_001985342.1 yhc00184 YP_001985343.1 yhc00185 YP_001985344.1 yhc00186 YP_001985345.1 yhc00187 YP_001985346.1 yhc00188 YP_001985347.1 yhc00189 YP_001985348.1 yhc00190 YP_001985349.1 ypc00421 YP_001985350.1 ypc00422 YP_001985351.1 ypc00423 YP_001985352.1 ypc00424 YP_001985353.1 ypc00425 YP_001985354.1 ypc00426 YP_001985356.1 ypc00427 YP_001985357.1 ypc00428 YP_001985358.1 yhc00191 YP_001985360.1 yhc00192 YP_001985361.1 yhc00193 YP_001985362.1 yhc00194 YP_001985363.1 yhc00195 YP_001985365.1 yhc00196 YP_001985366.1 ypc00430 YP_001985367.1 ypc00431 YP_001985368.1 yhc00197 YP_001985369.1 yhc00198 YP_001985370.1 yhc00199 YP_001985371.1 ypc00432 YP_001985372.1 yhc00200 YP_001985373.1 ypc00433 YP_001985374.1 ypc00435 YP_001985375.1 ypc00437 YP_001985376.1 yhc00201 YP_001985377.1 yhc00202 YP_001985378.1 yhc00203 YP_001985379.1 yhc00204 YP_001985380.1 yhc00205 YP_001985381.1 yhc00206 YP_001985382.1 yhc00207 YP_001985383.1 yhc00208 YP_001985384.1 ypc00438 YP_001985385.1 ypc00439 YP_001985386.1 ypc00440 YP_001985387.1 ypc00441 YP_001985388.1 ypc00442 YP_001985389.1 ypc00444 YP_001985390.1 ypc00445 YP_001985391.1 ypc00446 YP_001985392.1 ypc00447 YP_001985393.1 ypc00448 YP_001985394.1 yhc00209 YP_001985395.1 ypc00449 YP_001985396.1 ypc00450 YP_001985397.1 ypc00451 YP_001985398.1 ypc00452 YP_001985399.1 ypc00453 YP_001985400.1 ypc00454 YP_001985401.1 ypc00455 YP_001985402.1 ypc00456 YP_001985403.1 ypc00457 YP_001985404.1 yhc00210 YP_001985405.1 ypc00458 YP_001985406.1 ypc00459 YP_001985407.1 ypc00460 YP_001985408.1 ypc00461 YP_001985409.1 ypc00462 YP_001985410.1 ypc00463 YP_001985411.1 ypc00464 YP_001985412.1 ypc00465 YP_001985413.1 catalyzes the formation of fumarate from aspartate YP_001985414.1 yhc00211 YP_001985415.1 yhc00212 YP_001985416.1 ypc00467 YP_001985417.1 ypc00468 YP_001985418.1 ypc00469 YP_001985419.1 ypc00470 YP_001985420.1 ypc00471 YP_001985421.1 ypc00472 YP_001985422.1 ypc00473 YP_001985423.1 ypc00474 YP_001985424.1 ypc00475 YP_001985425.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001985426.1 ypc00477 YP_001985427.1 ypc00478 YP_001985428.1 yhc00213 YP_001985429.1 ypc00479 YP_001985430.1 ypc00480 YP_001985431.1 yhc00214 YP_001985432.1 ypc00481 YP_001985433.1 ypc00482 YP_001985434.1 ypc00483 YP_001985435.1 ypc00484 YP_001985436.1 yhc00215 YP_001985437.1 yhc00216 YP_001985438.1 ypc00485 YP_001985439.1 ypc00486 YP_001985440.1 ypc00487 YP_001985441.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_001985442.1 ypc00489 YP_001985443.1 ypc00490 YP_001985444.1 ypc00491 YP_001985445.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate YP_001985446.1 ypc00493 YP_001985447.1 ypc00494 YP_001985448.1 ypc00495 YP_001985449.1 yhc00217 YP_001985450.1 ypc00496 YP_001985451.1 yhc00218 YP_001985452.1 yhc00219 YP_001985453.1 ypc00499 YP_001985454.1 yhc00220 YP_001985455.1 yhc00221 YP_001985456.1 ypc00500 YP_001985457.1 ypc00501 YP_001985458.1 yhc00222 YP_001985459.1 ypc00502 YP_001985461.1 ypc00504 YP_001985462.1 ypc00505 YP_001985463.1 ypc00506 YP_001985464.1 yhc00223 YP_001985466.1 yhc00224 YP_001985468.1 yhc00225 YP_001985469.1 ypc00507 YP_001985470.1 ypc00508 YP_001985471.1 ypc00509 YP_001985472.1 ypc00510 YP_001985473.1 yhc00226 YP_001985474.1 yhc00227 YP_001985475.1 ypc00511 YP_001985476.1 ypc00512 YP_001985477.1 yhc00228 YP_001985478.1 yhc00229 YP_001985479.1 yhc00230 YP_001985480.1 yhc00231 YP_001985481.1 yhc00232 YP_001985482.1 yhc00233 YP_001985483.1 yhc00234 YP_001985484.1 yhc00235 YP_001985485.1 ypc00513 YP_001985486.1 yhc00236 YP_001985487.1 yhc00237 YP_001985488.1 yhc00238 YP_001985489.1 yhc00239 YP_001985490.1 yhc00240 YP_001985495.1 yhc00241 YP_001985496.1 ypc00514 YP_001985497.1 yhc00242 YP_001985498.1 ypc00515 YP_001985499.1 ypc00516 YP_001985500.1 yhc00243 YP_001985501.1 yhc00244 YP_001985505.1 VirD4 family YP_001985506.1 yhc00245 YP_001985507.1 yhc00246 YP_001985508.1 yhc00247 YP_001985509.1 yhc00248 YP_001985510.1 yhc00249 YP_001985511.1 yhc00250 YP_001985512.1 yhc00251 YP_001985513.1 yhc00252 YP_001985514.1 yhc00253 YP_001985515.1 yhc00254 YP_001985516.1 yhc00255 YP_001985517.1 yhc00256 YP_001985518.1 yhc00257 YP_001985519.1 yhc00258 YP_001985526.1 yhc00259 YP_001985532.1 yhc00260 YP_001985533.1 yhc00261 YP_001985534.1 yhc00262 YP_001985535.1 yhc00263 YP_001985536.1 yhc00264 YP_001985537.1 ypc00517 YP_001985538.1 yhc00265 YP_001985540.1 ypc00518 YP_001985541.1 catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA YP_001985543.1 ypc00519 YP_001985544.1 ypc00520 YP_001985545.1 ypc00521 YP_001985546.1 ypc00522 YP_001985547.1 ypc00523 YP_001985548.1 ypc00524 YP_001985549.1 ypc00525 YP_001985550.1 ypc00526 YP_001985551.1 catalyzes the formation of 5-alpha-androstane-3,17-dione from androsterone; Acts on other 3-alpha-hydroxysteroids and on 9-, 11- and 15-hydroxyprostaglandin. YP_001985552.1 ypc00528 YP_001985553.1 yhc00266 YP_001985554.1 yhc00267 YP_001985555.1 ypc00529 YP_001985556.1 yhc00268 YP_001985557.1 ypc00530 YP_001985558.1 ypc00531 YP_001985559.1 yhc00269 YP_001985560.1 yhc00270 YP_001985561.1 yhc00271 YP_001985562.1 yhc00272 YP_001985563.1 yhc00273 YP_001985564.1 yhc00274 YP_001985565.1 yhc00275 YP_001985566.1 yhc00276 YP_001985567.1 yhc00277 YP_001985568.1 yhc00278 YP_001985569.1 yhc00279 YP_001985570.1 yhc00280 YP_001985571.1 yhc00281 YP_001985572.1 yhc00282 YP_001985573.1 catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP YP_001985574.1 yhc00283 YP_001985575.1 yhc00284 YP_001985576.1 yhc00285 YP_001985577.1 yhc00286 YP_001985578.1 yhc00287 YP_001985579.1 ypc00533 YP_001985580.1 yhc00288 YP_001985581.1 yhc00289 YP_001985582.1 ypc00534 YP_001985583.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_001985585.1 yhc00290 YP_001985586.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001985587.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001985588.1 yhc00291 YP_001985589.1 ypc00536 YP_001985590.1 yhc00292 YP_001985591.1 ypc00537 YP_001985592.1 ypc00538 YP_001985593.1 ypc00539 YP_001985594.1 yhc00293 YP_001985595.1 ypc00540 YP_001985596.1 ypc00541 YP_001985597.1 yhc00294 YP_001985598.1 yhc00295 YP_001985599.1 ypc00542 YP_001985600.1 ypc00543 YP_001985601.1 ypc00544 YP_001985602.1 ypc00545 YP_001985603.1 ypc00546 YP_001985604.1 ypc00547 YP_001985605.1 ypc00548 YP_001985606.1 ypc00549 YP_001985610.1 yha00001 YP_001985611.1 yha00002 YP_001985612.1 yha00003 YP_001985613.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; possibly involved in prevention of copper toxicity YP_001985614.1 yha00004 YP_001985617.1 ypa00002 YP_001985618.1 ypa00003 YP_001985619.1 yha00005 YP_001985620.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001985621.1 yha00006 YP_001985622.1 LovR from Caulobacter crescentus is a response regulator part of a two-component signaling system that regulates photosensitive bacterial cell-surface and cell-cell attachment YP_001985623.1 ypa00005 YP_001985624.1 ypa00006 YP_001985625.1 ypa00007 YP_001985626.1 ypa00008 YP_001985627.1 ypa00009 YP_001985628.1 yha00007 YP_001985629.1 ypa00010 YP_001985630.1 ypa00011 YP_001985631.1 yha00008 YP_001985632.1 yha00009 YP_001985633.1 ypa00012 YP_001985634.1 ypa00013 YP_001985635.1 ypa00014 YP_001985640.1 ypa00015 YP_001985641.1 yha00010 YP_001985642.1 yha00011 YP_001985643.1 yha00012 YP_001985644.1 yha00013 YP_001985645.1 ypa00016 YP_001985646.1 ypa00017 YP_001985647.1 ypa00018 YP_001985650.1 ypa00019 YP_001985651.1 ypa00020 YP_001985652.1 ypa00021 YP_001985653.1 ypa00022 YP_001985655.1 ypa00023 YP_001985656.1 yha00014 YP_001985657.1 yha00015 YP_001985658.1 yha00016 YP_001985659.1 yha00017 YP_001985661.1 yha00018 YP_001985663.1 ypa00024 YP_001985664.1 yha00019 YP_001985665.1 ypa00025 YP_001985666.1 yha00020 YP_001985667.1 ypa00026 YP_001985668.1 Catalyzes the cycloisomerization of cis,cis-muconate YP_001985674.1 yha00021 YP_001985675.1 yha00022 YP_001985676.1 ypa00027 YP_001985677.1 yha00023 YP_001985678.1 ypa00028 YP_001985679.1 ypa00029 YP_001985680.1 yha00024 YP_001985681.1 ypa00030 YP_001985682.1 yha00025 YP_001985683.1 ypa00031 YP_001985684.1 yha00026 YP_001985685.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001985687.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001985688.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001985689.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_001985690.1 ypa00033 YP_001985692.1 yha00027 YP_001985693.1 ypa00034 YP_001985698.1 yha00028 YP_001985699.1 ypa00035 YP_001985700.1 ypa00036 YP_001985701.1 yha00029 YP_001985702.1 yha00030 YP_001985703.1 yha00031 YP_001985704.1 ypa00037 YP_001985707.1 ypa00038 YP_001985708.1 ypa00039 YP_001985709.1 ypa00040 YP_001985711.1 yha00032 YP_001985712.1 yha00033 YP_001985713.1 yha00034 YP_001985714.1 yha00035 YP_001985715.1 yha00036 YP_001985716.1 yha00037 YP_001985717.1 yha00038 YP_001985718.1 yha00039 YP_001985719.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001985720.1 yha00040 YP_001985721.1 ypa00041 YP_001985722.1 yha00041 YP_001985723.1 yha00042 YP_001985724.1 ypa00042 YP_001985725.1 yha00043 YP_001985726.1 yha00044 YP_001985727.1 yha00045 YP_001985728.1 yha00046 YP_001985729.1 yha00047 YP_001985730.1 ypa00043 YP_001985731.1 ypa00044 YP_001985732.1 yha00048 YP_001985733.1 ypa00045 YP_001985734.1 yha00049 YP_001985735.1 ypa00046 YP_001985736.1 ypa00047 YP_001985737.1 ypa00048 YP_001985738.1 ypa00049 YP_001985739.1 ypa00050 YP_001985740.1 ypa00051 YP_001985741.1 ypa00052 YP_001985742.1 ypa00053 YP_001985743.1 ypa00055 YP_001985744.1 ypa00056 YP_001985745.1 ypa00057 YP_001985746.1 yha00050 YP_001985747.1 ypa00058 YP_001985748.1 yha00051 YP_001985749.1 ypa00059 YP_001985750.1 ypa00060 YP_001985751.1 ypa00061 YP_001985752.1 ypa00062 YP_001985753.1 yha00052 YP_001985754.1 ypa00063 YP_001985755.1 ypa00064 YP_001985756.1 ypa00065 YP_001985757.1 ypa00066 YP_001985758.1 ypa00068 YP_001985759.1 ypa00069 YP_001985760.1 ypa00070 YP_001985763.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_001985764.1 ypa00071 YP_001985765.1 ypa00072 YP_001985766.1 ypa00073 YP_001985767.1 ypa00074 YP_001985769.1 ypa00075 YP_001985770.1 ypa00076 YP_001985772.1 yha00053 YP_001985773.1 yha00054 YP_001985774.1 yha00055 YP_001985775.1 ypa00077 YP_001985776.1 yha00056 YP_001985777.1 yha00057 YP_001985778.1 yha00058 YP_001985779.1 ypa00078 YP_001985781.1 ypa00079 YP_001985782.1 yha00059 YP_001985783.1 yha00060 YP_001985784.1 yha00061 YP_001985785.1 yha00062 YP_001985786.1 yha00063 YP_001985787.1 ypa00080 YP_001985788.1 ypa00081 YP_001985789.1 yha00064 YP_001985790.1 yha00065 YP_001985791.1 yha00066 YP_001985792.1 ypa00082 YP_001985793.1 ypa00083 YP_001985794.1 yha00067 YP_001985795.1 ypa00084 YP_001985797.1 ypa00085 YP_001985798.1 ypa00086 YP_001985799.1 ypa00087 YP_001985800.1 ypa00088 YP_001985801.1 ypa00089 YP_001985802.1 ypa00090 YP_001985803.1 ypa00091 YP_001985804.1 catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001985805.1 ypa00093 YP_001985806.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001985807.1 ypa00094 YP_001985808.1 ypa00095 YP_001985809.1 ypa00096 YP_001985810.1 ypa00097 YP_001985811.1 ypa00098 YP_001985813.1 ypa00099 YP_001985817.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001985818.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001985819.1 yha00068 YP_001985820.1 ypa00100 YP_001985821.1 yha00069 YP_001985822.1 Enables the enzymatic reduction of mercuric ions to elemental mercury YP_001985823.1 yha00070 YP_001985825.1 ypa00102 YP_001985826.1 ypa00103 YP_001985827.1 yha00071 YP_001985828.1 ypa00104 YP_001985829.1 ypa00105 YP_001985830.1 ypa00106 YP_001985831.1 ypa00107 YP_001985832.1 ypa00108 YP_001985833.1 ypa00109 YP_001985834.1 ypa00110 YP_001985836.1 yha00072 YP_001985837.1 ypa00111 YP_001985838.1 yha00073 YP_001985839.1 ypa00112 YP_001985840.1 ypa00113 YP_001985841.1 ypa00114 YP_001985842.1 ypa00115 YP_001985843.1 ypa00116 YP_001985844.1 ypa00117 YP_001985845.1 ypa00118 YP_001985846.1 yha00074 YP_001985847.1 ypa00119 YP_001985848.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001985849.1 ypa00120 YP_001985850.1 ypa00121 YP_001985851.1 yha00076 YP_001985852.1 yha00077 YP_001985853.1 ypa00122 YP_001985854.1 yha00078 YP_001985855.1 yha00079 YP_001985856.1 yha00080 YP_001985857.1 ypa00123 YP_001985858.1 yha00081 YP_001985860.1 ypa00124 YP_001985861.1 yha00082 YP_001985862.1 yha00083 YP_001985863.1 ypa00125 YP_001985864.1 yha00084 YP_001985865.1 ypa00126 YP_001985866.1 ypa00127 YP_001985867.1 ypa00128 YP_001985868.1 ypa00129 YP_001985869.1 ypa00130 YP_001985870.1 ypa00131 YP_001985871.1 yha00085 YP_001985875.1 yha00086 YP_001985876.1 yha00087 YP_001985877.1 ypa00132 YP_001985878.1 ypa00133 YP_001985879.1 ypa00134 YP_001985880.1 ypa00135 YP_001985882.1 ypa00136 YP_001985883.1 yha00088 YP_001985884.1 ypa00137 YP_001985888.1 catalyzes the formation of fumarate from aspartate YP_001985889.1 ypa00138 YP_001985890.1 ypa00139 YP_001985891.1 yha00089 YP_001985892.1 ypa00140 YP_001985893.1 yha00090 YP_001985894.1 yha00091 YP_001985895.1 ypa00141 YP_001985896.1 yha00092 YP_001985897.1 yha00093 YP_001985898.1 yha00094 YP_001985899.1 ypa00142 YP_001985900.1 ypa00143 YP_001985901.1 ypa00144 YP_001985902.1 ypa00145 YP_001985903.1 ypa00146 YP_001985904.1 ypa00147 YP_001985905.1 yha00095 YP_001985906.1 yha00096 YP_001985907.1 yha00097 YP_001985908.1 yha00098 YP_001985909.1 ypa00148 YP_001985910.1 ypa00149 YP_001985911.1 yha00099 YP_001985912.1 yha00100 YP_001985913.1 ypa00150 YP_001985914.1 ypa00151 YP_001985915.1 ypa00152 YP_001985916.1 ypa00153 YP_001985917.1 ypa00154 YP_001985918.1 yha00101 YP_001985919.1 ypa00155 YP_001985920.1 ypa00156 YP_001985922.1 ypa00157 YP_001985923.1 yha00102 YP_001985924.1 ypa00158 YP_001985925.1 ypa00159 YP_001985926.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_001985927.1 yha00103 YP_001985928.1 3'-5' exonuclease of DNA polymerase III YP_001985929.1 ypa00162 YP_001985930.1 ypa00163 YP_001985931.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001985933.1 blocks the formation of polar Z-ring septums YP_001985934.1 ypa00164 YP_001985935.1 ypa00165 YP_001985936.1 ypa00166 YP_001985937.1 ypa00167 YP_001985938.1 yha00104 YP_001985939.1 ypa00168 YP_001985940.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001985945.1 ypa00169 YP_001985946.1 ypa00170 YP_001985951.1 yha00105 YP_001985952.1 ypa00171 YP_001985953.1 ypa00172 YP_001985954.1 yha00106 YP_001985955.1 ypa00173 YP_001985956.1 ypa00174 YP_001985957.1 ypa00175 YP_001985958.1 ypa00176 YP_001985959.1 ypa00177 YP_001985960.1 ypa00178 YP_001985961.1 ypa00179 YP_001985962.1 yha00107 YP_001985963.1 yha00108 YP_001985964.1 ypa00180 YP_001985965.1 yha00109 YP_001985966.1 yha00110 YP_001985967.1 yha00111 YP_001985968.1 ypa00181 YP_001985969.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001985970.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001985971.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001985972.1 yha00112 YP_001985973.1 ypa00182 YP_001985977.1 ypa00183 YP_001985978.1 ypa00184 YP_001985981.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 YP_001985982.1 catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine YP_001985983.1 catalyzes the formation of precorrin-3 from precorrin-2 YP_001985984.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_001985986.1 catalyzes the formation of precorrin 6x from precorrin 5 YP_001985987.1 yha00113