-- dump date   	20140620_025833
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
YP_002776383.1	fragment
YP_002776387.1	fragment
YP_002776389.1	fragment
YP_002776396.1	fragment
YP_002776398.1	fragment
YP_002776489.1	fragment
YP_002776490.1	fragment
YP_002776492.1	fragment
YP_002776495.1	fragment
YP_002776497.1	fragment
YP_002776503.1	fragment
YP_002776504.1	fragment
YP_002776507.1	fragment
YP_002776508.1	fragment
YP_002776509.1	fragment
YP_002776510.1	fragment
YP_002776511.1	fragment
YP_002776512.1	fragment
YP_002776519.1	fragment
YP_002776521.1	fragment
YP_002776524.1	fragment
YP_002776531.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_002776562.1	protein synonym:O-acetylserine (thiol)-lyase; protein synonym:O-acetylserine sulfhydrylase
YP_002776595.1	bifunctional protein
YP_002776654.1	protein synonym:aspartase
YP_002776702.1	fragment
YP_002776705.1	fragment
YP_002776706.1	fragment
YP_002776728.1	fragment
YP_002776732.1	fragment
YP_002776734.1	fragment
YP_002776752.1	activates fatty acids by binding to coenzyme A
YP_002776757.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_002776763.1	fragment
YP_002776764.1	fragment
YP_002776774.1	fragment
YP_002776775.1	fragment
YP_002776780.1	fragment
YP_002776806.1	protein synonym:phosphate-transporting ATPase
YP_002776816.1	fragment
YP_002776819.1	fragment
YP_002776826.1	fragment
YP_002776827.1	fragment
YP_002776828.1	fragment
YP_002776847.1	fragment
YP_002776849.1	fragment
YP_002776852.1	fragment
YP_002776950.1	protein synonym:cytosine-specific DNA methyltransferase
YP_002776952.1	protein synonym:endonuclease
YP_002776953.1	protein synonym:very short patch repair protein
YP_002776984.1	fragment
YP_002776986.1	fragment
YP_002776987.1	fragment
YP_002777006.1	fragment
YP_002777018.1	fragment
YP_002777022.1	fragment
YP_002777025.1	fragment
YP_002777026.1	protein synonym:reverse transcriptase
YP_002777029.1	fragment
YP_002777030.1	fragment
YP_002777031.1	fragment
YP_002777032.1	fragment
YP_002777033.1	fragment
YP_002777039.1	protein synonym:acyl-CoA synthetase
YP_002777045.1	protein synonym:acyl-CoA thiolase
YP_002777064.1	protein synonym:pyruvate, orthophosphate dikinase
YP_002777071.1	protein synonym:phosphotyrosine phosphatase
YP_002777074.1	fragment
YP_002777075.1	fragment
YP_002777081.1	protein synonym:acyl-CoA synthetase
YP_002777084.1	protein synonym:acyl-CoA thiolase
YP_002777107.1	Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate
YP_002777113.1	protein synonym:acyl-CoA synthetase
YP_002777121.1	fragment
YP_002777124.1	fragment
YP_002777134.1	protein synonym:4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
YP_002777139.1	catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family
YP_002777140.1	fragment
YP_002777141.1	fragment
YP_002777142.1	fragment
YP_002777143.1	fragment
YP_002777152.1	protein synonym:1,2-dihydro-1,2- dihydroxynaphthalene dehydrogenase
YP_002777161.1	fragment
YP_002777162.1	fragment
YP_002777163.1	fragment
YP_002777164.1	fragment
YP_002777168.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_002777169.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_002777213.1	protein synonym:arsenite resistance pump catalytic subunit
YP_002777234.1	fragment
YP_002777235.1	fragment
YP_002777258.1	protein synonym:aconitate hydratase
YP_002777259.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
YP_002777267.1	catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate
YP_002777291.1	fragment
YP_002777295.1	fragment
YP_002777296.1	fragment
YP_002777302.1	protein synonym:5-keto-D-gluconate 5-reductase
YP_002777315.1	fragment
YP_002777347.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_002777348.1	protein synonym:nucleotide exchange factor
YP_002777357.1	protein synonym:18-kDa antigen
YP_002777376.1	fragment
YP_002777377.1	fragment
YP_002777378.1	fragment
YP_002777379.1	fragment
YP_002777402.1	bifunctional protein
YP_002777406.1	protein synonym:trehalose-6-phosphate synthase
YP_002777435.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_002777465.1	catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent
YP_002777483.1	with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism
YP_002777485.1	protein synonym:precorrin isomerase
YP_002777486.1	bifunctional protein; protein synonym:cobalamin biosynthesis protein CobIJ
YP_002777496.1	fragment
YP_002777497.1	fragment
YP_002777515.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_002777516.1	fragment
YP_002777517.1	fragment
YP_002777571.1	bifunctional protein
YP_002777579.1	protein synonym:UMP pyrophosphorylase
YP_002777617.1	fragment
YP_002777618.1	fragment
YP_002777621.1	protein synonym:O-acetylserine (thiol)-lyase; protein synonym:O-acetylserine sulfhydrylase
YP_002777642.1	protein synonym:peptidase M
YP_002777664.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_002777665.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif
YP_002777684.1	protein synonym:phosphoprotein phosphatase
YP_002777689.1	protein synonym:phosphoriboisomerase A
YP_002777691.1	protein synonym:xylulose kinase
YP_002777706.1	biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate
YP_002777738.1	protein synonym:reverse transcriptase
YP_002777744.1	fragment
YP_002777745.1	fragment
YP_002777756.1	protein synonym:precorrin-6A reductase
YP_002777758.1	protein synonym:precorrin-6Y methylase
YP_002777762.1	protein synonym:prolidase
YP_002777767.1	TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes
YP_002777779.1	protein synonym:AAA family ATPase
YP_002777784.1	long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors
YP_002777785.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis
YP_002777789.1	protein synonym:5-methyltetrahydrofolate-- homocysteine methyltransferase
YP_002777805.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_002777809.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
YP_002777814.1	with HmuTU is involved in the transport of hemin
YP_002777818.1	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
YP_002777826.1	catalyzes the formation of malate from glyoxylate and acetyl-CoA
YP_002777829.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine
YP_002777834.1	part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
YP_002777838.1	protein synonym:CDP-diacylglycerol--glycerol-3- phosphate 3-phosphatidyltransferase
YP_002777841.1	protein synonym:acyl-CoA synthetase
YP_002777849.1	synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
YP_002777850.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
YP_002777856.1	CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
YP_002777859.1	protein synonym:recombination protein N
YP_002777860.1	catalyzes the phosphorylation of NAD to NADP
YP_002777865.1	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)
YP_002777866.1	responsible for recognizing base lesions in the genome and initiating base excision DNA repair
YP_002777871.1	activates fatty acids by binding to coenzyme A
YP_002777872.1	catalyzes the formation of arginine from (N-L-arginino)succinate
YP_002777873.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
YP_002777874.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
YP_002777875.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation
YP_002777876.1	catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine
YP_002777877.1	catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate
YP_002777878.1	bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate
YP_002777879.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
YP_002777881.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
YP_002777882.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
YP_002777884.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
YP_002777891.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_002777897.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
YP_002777899.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain
YP_002777901.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
YP_002777911.1	has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair
YP_002777924.1	protein synonym:thioesterase II
YP_002777925.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002777929.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
YP_002777930.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
YP_002777931.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
YP_002777932.1	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
YP_002777934.1	with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
YP_002777939.1	PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers
YP_002777940.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
YP_002777941.1	protein synonym:inositol-phosphate phosphatase
YP_002777942.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis
YP_002777944.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
YP_002777947.1	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis
YP_002777948.1	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
YP_002777949.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_002777953.1	catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide
YP_002777954.1	catalyzes the formation of oxaloacetate from L-aspartate
YP_002777955.1	3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate
YP_002777962.1	catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine
YP_002777967.1	catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source
YP_002777968.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol
YP_002777973.1	DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium
YP_002777974.1	catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine
YP_002777975.1	catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate
YP_002777977.1	protein synonym:(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase
YP_002777985.1	catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic
YP_002777986.1	catalyzes the formation of acetate from pyruvate
YP_002777989.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase
YP_002777992.1	protein synonym:23S rRNA pseudouridine synthase
YP_002777993.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
YP_002777997.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_002777998.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin)
YP_002778005.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
YP_002778007.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
YP_002778008.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
YP_002778010.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
YP_002778011.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YP_002778012.1	protein synonym:D-alanyl-D-alanine-adding enzyme; protein synonym:UDP-MurNAc-pentapeptide synthetase
YP_002778013.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate
YP_002778014.1	protein synonym:penicillin-binding protein; protein synonym:peptidoglycan glycosyltransferase
YP_002778017.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
YP_002778027.1	protein synonym:phytoene desaturase
YP_002778031.1	protein synonym:protein kinase L
YP_002778036.1	protein synonym:glucose kinase
YP_002778041.1	protein synonym:acyl-CoA synthetase
YP_002778046.1	contains 3'-5'exonuclease domain
YP_002778048.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_002778063.1	bifunctional protein; protein synonym:bifunctional adenosylcobalamin biosynthesis protein
YP_002778064.1	catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole
YP_002778065.1	catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole
YP_002778066.1	catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
YP_002778067.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
YP_002778068.1	catalyzes the removal of N-terminal amino acids preferably leucine from various peptides
YP_002778072.1	lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein
YP_002778073.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_002778076.1	protein synonym:glutamate--ammonia ligase
YP_002778084.1	catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme
YP_002778085.1	protein synonym:glutamate--ammonia ligase
YP_002778087.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
YP_002778089.1	protein synonym:proline iminopeptidase
YP_002778097.1	protein synonym:arsenite-transporting ATPase membrane subunit
YP_002778098.1	bifunctional protein
YP_002778103.1	protein synonym:phosphotyrosine phosphatase
YP_002778105.1	CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YP_002778112.1	E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC
YP_002778114.1	protein synonym:[acyl-carrier-protein] S-malonyltransferase
YP_002778115.1	carries the fatty acid chain in fatty acid biosynthesis
YP_002778116.1	FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP
YP_002778117.1	protein synonym:carboxyltransferase
YP_002778127.1	synthesizes RNA primers at the replication forks
YP_002778129.1	dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate
YP_002778133.1	Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002778138.1	involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA
YP_002778143.1	protein synonym:kdp operon response regulator
YP_002778144.1	protein synonym:two-component histidine kinase
YP_002778147.1	catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
YP_002778150.1	catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia
YP_002778152.1	Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
YP_002778156.1	protein synonym:ATP-binding protein
YP_002778158.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
YP_002778159.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_002778160.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
YP_002778162.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
YP_002778164.1	catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite
YP_002778165.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_002778166.1	protein synonym:ATP sulfurylase large subunit
YP_002778169.1	protein synonym:beta-ketoacyl-ACP synthase
YP_002778171.1	fragment
YP_002778172.1	fragment
YP_002778174.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. tuberculosis this protein regulates polyketide synthases and secreted or membrane proteins
YP_002778178.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_002778179.1	bifunctional protein; protein synonym:APS kinase; protein synonym:ATP sulfurylase large subunit
YP_002778180.1	protein synonym:UDP-N-acetylmuramyl-tripeptide synthetase; protein synonym:meso-diaminopimelate-adding enzyme
YP_002778190.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
YP_002778193.1	protein synonym:water channel
YP_002778197.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
YP_002778211.1	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria
YP_002778214.1	Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway
YP_002778219.1	protein synonym:DABA acetyltransferase
YP_002778220.1	catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde
YP_002778221.1	N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid
YP_002778223.1	protein synonym:regulatory protein SIR2 homolog
YP_002778224.1	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis
YP_002778225.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
YP_002778226.1	involved in the peptidyltransferase reaction during translation
YP_002778229.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
YP_002778231.1	protein synonym:folylpoly-gamma-glutamate synthetase; protein synonym:tetrahydrofolylpolyglutamate synthase
YP_002778232.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
YP_002778241.1	protein synonym:beta-ketoadipate--succinyl-CoA transferase
YP_002778242.1	protein synonym:beta-ketoadipate--succinyl-CoA transferase
YP_002778245.1	protein synonym:3-carboxymuconate lactonizing enzyme
YP_002778246.1	bifunctional protein
YP_002778248.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002778250.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_002778262.1	protein synonym:inosose dehydratase
YP_002778267.1	protein synonym:glucose kinase
YP_002778277.1	catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis
YP_002778278.1	binds and unfolds substrates as part of the ClpXP protease
YP_002778279.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_002778280.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_002778281.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
YP_002778284.1	catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity
YP_002778289.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_002778295.1	protein synonym:truncated hemoglobin
YP_002778301.1	ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence
YP_002778309.1	converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer
YP_002778311.1	protein synonym:steroyl-CoA delta(9)-desaturase
YP_002778321.1	3'-5' exoribonuclease specific for small oligoribonuclotides
YP_002778326.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
YP_002778332.1	HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine
YP_002778333.1	RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs
YP_002778335.1	protein synonym:O-acetylserine (thiol)-lyase; protein synonym:O-acetylserine sulfhydrylase
YP_002778337.1	protein synonym:O-acetylserine (thiol)-lyase; protein synonym:O-acetylserine sulfhydrylase
YP_002778342.1	involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA
YP_002778343.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
YP_002778344.1	bifunctional protein
YP_002778350.1	catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain
YP_002778353.1	protein synonym:2-oxo-3-deoxygalactonate kinase
YP_002778354.1	protein synonym:2-oxo-3-deoxygalactonate 6-phosphate aldolase
YP_002778359.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
YP_002778364.1	protein synonym:adenylyl cyclase
YP_002778370.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
YP_002778373.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
YP_002778374.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
YP_002778375.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
YP_002778376.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
YP_002778377.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
YP_002778378.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.
YP_002778379.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
YP_002778380.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
YP_002778385.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
YP_002778386.1	RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002778387.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
YP_002778388.1	catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
YP_002778389.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
YP_002778390.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
YP_002778392.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
YP_002778395.1	bifunctional protein
YP_002778401.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002778405.1	protein synonym:acyl-CoA synthetase
YP_002778414.1	protein synonym:PAP phosphatase
YP_002778415.1	in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis
YP_002778416.1	with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP
YP_002778421.1	protein synonym:phosphotyrosine phosphatase
YP_002778422.1	protein synonym:endopeptidase Clp
YP_002778423.1	hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
YP_002778425.1	protein synonym:beta-ketoacyl-ACP synthase II
YP_002778435.1	catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA
YP_002778441.1	protein synonym:glucosamine-6-phosphate isomerase
YP_002778443.1	protein synonym:phosphotransferase system enzyme I
YP_002778444.1	protein synonym:histidine-containing protein
YP_002778445.1	protein synonym:PTS sugar-specific EIIC component
YP_002778446.1	protein synonym:PTS sugar-specific EIIB component
YP_002778447.1	protein synonym:PTS sugar-specific EIIA component
YP_002778458.1	catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_002778461.1	protein synonym:urate oxidase
YP_002778476.1	protein synonym:proton-translocating NAD(P) transhydrogenase
YP_002778477.1	protein synonym:proton-translocating NAD(P) transhydrogenase
YP_002778478.1	protein synonym:proton-translocating NAD(P) transhydrogenase
YP_002778481.1	activates fatty acids by binding to coenzyme A
YP_002778497.1	bifunctional protein
YP_002778499.1	fragment
YP_002778501.1	fragment
YP_002778502.1	fragment
YP_002778511.1	protein synonym:acetyl-CoA synthetase
YP_002778513.1	protein synonym:3-ketoacyl-ACP reductase
YP_002778518.1	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
YP_002778520.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_002778536.1	catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA
YP_002778556.1	protein synonym:ketopantoate reductase
YP_002778591.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
YP_002778610.1	protein synonym:steroyl-CoA delta(9)-desaturase
YP_002778611.1	protein synonym:glutamate--ammonia ligase
YP_002778631.1	protein synonym:O-acetylhomoserine sulfhydrylase
YP_002778643.1	catalyzes the formation of fumarate from aspartate
YP_002778679.1	protein synonym:Rieske [2Fe-2S] family protein
YP_002778686.1	bifunctional protein; protein synonym:FolD bifunctional protein
YP_002778687.1	protein synonym:formyl-FH(4) hydrolase
YP_002778697.1	protein synonym:L-serine deaminase
YP_002778701.1	protein synonym:creatinase
YP_002778721.1	in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone
YP_002778730.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_002778734.1	in Corynebacterium glutamicum this enzyme catalyzes the conversion of maleylpyruvate into fumarylpyruvate in a glutathione-independent gentisate pathway; dependent on mycothiol
YP_002778746.1	protein synonym:acetoacetyl-CoA thiolase
YP_002778751.1	protein synonym:phosphotyrosine phosphatase
YP_002778763.1	Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues
YP_002778771.1	protein synonym:acyl-CoA synthetase
YP_002778796.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
YP_002778797.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
YP_002778798.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
YP_002778799.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
YP_002778803.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002778805.1	protein synonym:biotin carboxylase/biotin carboxyl carrier protein
YP_002778806.1	protein synonym:carboxyltransferase
YP_002778811.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002778817.1	protein synonym:adenylyl cyclase
YP_002778818.1	protein synonym:threonine deaminase
YP_002778831.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
YP_002778832.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
YP_002778846.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
YP_002778848.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
YP_002778849.1	binds directly to 23S ribosomal RNA
YP_002778850.1	Modulates Rho-dependent transcription termination
YP_002778851.1	forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
YP_002778852.1	functions as a heterodimer along with HadA or HadC in fatty acid biosynthesis; fatty acid synthase type II; FAS-II
YP_002778854.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif
YP_002778855.1	nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription
YP_002778856.1	metalloprotease
YP_002778859.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone
YP_002778863.1	SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis
YP_002778867.1	catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate
YP_002778869.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
YP_002778887.1	catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
YP_002778900.1	protein synonym:thiol-disulfide oxidoreductase
YP_002778901.1	protein synonym:thiol-disulfide oxidoreductase
YP_002778903.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
YP_002778914.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
YP_002778915.1	bifunctional protein
YP_002778916.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
YP_002778917.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
YP_002778918.1	modulates transcription in response to the NADH/NAD(+) redox state
YP_002778924.1	catalyzes the formation of L-proline from pyrroline-5-carboxylate
YP_002778934.1	2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
YP_002778950.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
YP_002778957.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
YP_002778959.1	produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine
YP_002778962.1	protein synonym:acyl-CoA synthetase
YP_002778971.1	protein synonym:Rieske [2Fe-2S] family protein
YP_002778973.1	fragment
YP_002778974.1	fragment
YP_002778980.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002778984.1	protein synonym:3-ketoacyl-ACP reductase
YP_002778985.1	protein synonym:acyl-CoA synthetase
YP_002778995.1	protein synonym:Rieske [2Fe-2S] family protein
YP_002779029.1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is a general stress response regulator; expressed in stationary phase and under nitrogen depletion and cold shock
YP_002779031.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
YP_002779032.1	converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA
YP_002779046.1	catalyzes the hydrolysis of allophanate
YP_002779050.1	E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component
YP_002779055.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
YP_002779063.1	catalyzes the degradation of histidine to urocanate and ammmonia
YP_002779067.1	catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine
YP_002779068.1	protein synonym:CDP-diacylglycerol--serine O-phosphatidyltransferase
YP_002779073.1	subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
YP_002779074.1	subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
YP_002779075.1	subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone
YP_002779076.1	subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport
YP_002779077.1	subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
YP_002779078.1	subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport
YP_002779080.1	ATP-dependent carboxylate-amine ligase
YP_002779084.1	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
YP_002779086.1	protein synonym:exonuclease III
YP_002779089.1	required for the synthesis of the hydromethylpyrimidine moiety of thiamine
YP_002779090.1	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine
YP_002779091.1	protein synonym:adenylyl cyclase
YP_002779095.1	functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate
YP_002779098.1	Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate
YP_002779102.1	protein synonym:protein kinase G
YP_002779103.1	AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
YP_002779104.1	catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate
YP_002779151.1	protein synonym:phosphoribosylglycinamide formyltransferase
YP_002779153.1	catalyzes the formation of precorrin 6x from precorrin 5
YP_002779154.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
YP_002779166.1	protein synonym:flavohemoglobin; protein synonym:nitric oxide dioxygenase
YP_002779172.1	protein synonym:dienelactone hydrolase
YP_002779176.1	protein synonym:RNase HI; protein synonym:type 1 RNase H
YP_002779189.1	protein synonym:acyl-CoA synthetase
YP_002779199.1	protein synonym:acyl-CoA thiolase
YP_002779202.1	catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate
YP_002779210.1	activates fatty acids by binding to coenzyme A
YP_002779213.1	protein synonym:fumarylacetoacetate hydrolase
YP_002779223.1	catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine
YP_002779228.1	protein synonym:2,3 dihydro-2,3 dihydroxybenzoate synthase
YP_002779231.1	protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters
YP_002779239.1	protein synonym:O6-methylguanine-DNA alkyltransferase
YP_002779241.1	protein synonym:O6-methylguanine-DNA alkyltransferase
YP_002779249.1	protein synonym:3-ketoacyl-ACP reductase
YP_002779268.1	protein synonym:gluconate kinase
YP_002779273.1	bifunctional protein; protein synonym:2-keto-3-deoxy-6-phosphogluconate aldolase; protein synonym:2-keto-4-hydroxyglutarate aldolase
YP_002779274.1	catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate
YP_002779275.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_002779278.1	protein synonym:cis,cis-muconate lactonizing enzyme I
YP_002779292.1	protein synonym:electron transfer component
YP_002779293.1	catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol
YP_002779295.1	catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin
YP_002779300.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_002779303.1	Catalyzes the conversion of citrate to isocitrate
YP_002779305.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase
YP_002779338.1	proposed role in polysaccahride synthesis
YP_002779382.1	bifunctional protein; protein synonym:2-keto-3-deoxy-6-phosphogluconate aldolase; protein synonym:2-keto-4-hydroxyglutarate aldolase
YP_002779393.1	protein synonym:GABA permease
YP_002779402.1	initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione
YP_002779409.1	protein synonym:terminal oxygenase
YP_002779411.1	protein synonym:Baeyer-Villiger monooxygenase
YP_002779436.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002779437.1	activates fatty acids by binding to coenzyme A
YP_002779455.1	catalyzes the formation of protocatechuate from 4-hydroxybenzoate
YP_002779478.1	protein synonym:cyclopropane-fatty-acyl- phospholipid synthase
YP_002779479.1	protein synonym:cyclopropane-fatty-acyl- phospholipid synthase
YP_002779481.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins
YP_002779483.1	catalyzes the formation of malate from glyoxylate and acetyl-CoA
YP_002779484.1	paralogs to the E1 component of pyruvate dehydrogenase subunit E1
YP_002779488.1	protein synonym:malic enzyme
YP_002779489.1	catalyzes the formation of S-ureidoglycolate and urea from allantoate
YP_002779491.1	catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate
YP_002779492.1	protein synonym:tartronate semialdehyde reductase
YP_002779501.1	involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth
YP_002779504.1	protein synonym:benzyl alcohol dehydrogenase
YP_002779505.1	protein synonym:histidase
YP_002779512.1	protein synonym:quinone oxidoreductase
YP_002779522.1	catalyzes conversion of chorismate to salicylate, in mycobactin siderophore construction; requires Mg(2+) for function
YP_002779524.1	protein synonym:L-ornithine 5-monooxygenase
YP_002779526.1	catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine
YP_002779539.1	protein synonym:L-serine deaminase
YP_002779553.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002779554.1	protein synonym:acyl-CoA synthetase
YP_002779556.1	protein synonym:acyl-CoA synthetase
YP_002779558.1	protein synonym:3-ketoacyl-ACP reductase
YP_002779561.1	protein synonym:acyl-CoA thiolase
YP_002779573.1	protein synonym:acyl-CoA synthetase
YP_002779590.1	activates fatty acids by binding to coenzyme A
YP_002779594.1	protein synonym:2-dehydro-3-deoxygluconokinase
YP_002779595.1	bifunctional protein; protein synonym:2-keto-3-deoxy-6-phosphogluconate aldolase; protein synonym:2-keto-4-hydroxyglutarate aldolase
YP_002779613.1	protein synonym:GABA permease
YP_002779622.1	protein synonym:phosphotyrosine phosphatase
YP_002779641.1	protein synonym:acyl-CoA synthetase
YP_002779644.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002779651.1	bifunctional protein
YP_002779653.1	protein synonym:acyl-CoA thiolase
YP_002779655.1	protein synonym:acyl-CoA thiolase
YP_002779658.1	protein synonym:thioesterase II
YP_002779662.1	fragment
YP_002779663.1	fragment
YP_002779669.1	protein synonym:phosphotyrosine phosphatase
YP_002779677.1	protein synonym:Rieske [2Fe-2S] family protein
YP_002779680.1	protein synonym:acyl-CoA synthetase
YP_002779682.1	protein synonym:acyl-CoA synthetase
YP_002779686.1	protein synonym:acyl-CoA synthetase
YP_002779700.1	protein synonym:xylulose kinase
YP_002779704.1	protein synonym:acyl-CoA synthetase
YP_002779722.1	multifunctional protein
YP_002779723.1	protein synonym:3-ketoacyl-CoA thiolase; protein synonym:fatty oxidation complex beta subunit
YP_002779731.1	allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide
YP_002779735.1	protein synonym:glutamate--ammonia ligase
YP_002779750.1	catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine
YP_002779769.1	protein synonym:phenylacetyl-CoA ligase
YP_002779770.1	protein synonym:phenylacetic acid degradation protein
YP_002779771.1	protein synonym:phenylacetic acid degradation protein
YP_002779772.1	protein synonym:phenylacetic acid degradation protein
YP_002779773.1	with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation
YP_002779774.1	with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA
YP_002779779.1	catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA
YP_002779781.1	protein synonym:phenylacetic acid degradation protein
YP_002779805.1	multifunctional protein
YP_002779809.1	thiamine-pyrophosphate requiring enzyme
YP_002779814.1	protein synonym:acyl-CoA thiolase
YP_002779841.1	E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_002779842.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
YP_002779843.1	fragment
YP_002779844.1	fragment
YP_002779845.1	fragment
YP_002779846.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine
YP_002779847.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
YP_002779849.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_002779850.1	protein synonym:L-serine deaminase
YP_002779851.1	protein synonym:carboxyltransferase
YP_002779887.1	bifunctional protein
YP_002779891.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002779911.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002779913.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002779917.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002779951.1	protein synonym:GABA transaminase
YP_002779982.1	protein synonym:peroxiredoxin
YP_002780005.1	fragment
YP_002780006.1	fragment
YP_002780010.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002780014.1	protein synonym:acetyl-CoA synthetase
YP_002780024.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_002780033.1	protein synonym:5-keto-D-gluconate 5-reductase
YP_002780034.1	protein synonym:gluconate kinase
YP_002780039.1	catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids
YP_002780061.1	catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate
YP_002780064.1	fragment
YP_002780065.1	fragment
YP_002780066.1	fragment
YP_002780076.1	fragment
YP_002780077.1	fragment
YP_002780078.1	protein synonym:reverse transcriptase
YP_002780081.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002780082.1	protein synonym:acetyl-CoA synthetase
YP_002780091.1	fragment
YP_002780092.1	fragment
YP_002780101.1	E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
YP_002780125.1	protein synonym:proline iminopeptidase
YP_002780138.1	protein synonym:GABA permease
YP_002780139.1	fragment
YP_002780140.1	fragment
YP_002780156.1	protein synonym:aspartase
YP_002780157.1	protein synonym:L-asparagine amidohydrolase
YP_002780158.1	protein synonym:phosphotyrosine phosphatase
YP_002780159.1	protein synonym:acyl-CoA thiolase
YP_002780164.1	catalyzes the formation of phosphoenolpyruvate from pyruvate
YP_002780166.1	protein synonym:acyl-CoA synthetase
YP_002780182.1	protein synonym:steroyl-CoA delta(9)-desaturase
YP_002780192.1	protein synonym:rhodanese
YP_002780200.1	fragment
YP_002780201.1	fragment
YP_002780216.1	protein synonym:glutamate--ammonia ligase
YP_002780224.1	activates fatty acids by binding to coenzyme A
YP_002780230.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
YP_002780233.1	catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate
YP_002780237.1	catalyzes the formation of citrate from acetyl-CoA and oxaloacetate
YP_002780254.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
YP_002780310.1	protein synonym:thioesterase II
YP_002780311.1	protein synonym:biotin carboxylase/biotin carboxyl carrier protein
YP_002780313.1	protein synonym:carboxyltransferase
YP_002780317.1	protein synonym:acyl-CoA synthetase
YP_002780344.1	Represses a number of genes involved in the response to DNA damage
YP_002780359.1	protein synonym:Rieske [2Fe-2S] family protein
YP_002780368.1	fragment
YP_002780369.1	fragment
YP_002780380.1	protein synonym:18-kDa antigen
YP_002780414.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
YP_002780415.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_002780416.1	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
YP_002780417.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
YP_002780446.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002780487.1	AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase
YP_002780510.1	protein synonym:muramidase
YP_002780531.1	protein synonym:phosphotransacetylase
YP_002780543.1	catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source
YP_002780545.1	protein synonym:cobalamin biosynthesis protein; protein synonym:hydrogenobyrinic acid a,c-diamide cobaltochelatase
YP_002780546.1	protein synonym:cobalamin biosynthesis protein; protein synonym:hydrogenobyrinic acid a,c-diamide cobaltochelatase
YP_002780549.1	protein synonym:GABA permease
YP_002780556.1	bifunctional protein
YP_002780565.1	bifunctional protein; protein synonym:riboflavin biosynthesis protein RibA
YP_002780567.1	protein synonym:malic enzyme
YP_002780577.1	protein synonym:GABA permease
YP_002780582.1	functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate
YP_002780588.1	specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport
YP_002780600.1	protein synonym:steroid delta-isomerase
YP_002780608.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_002780609.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_002780617.1	fragment
YP_002780635.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
YP_002780652.1	bifunctional protein
YP_002780657.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: in Mycobacterium bovis this protein has been shown to be active at high temperatures and during stationary phase
YP_002780668.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
YP_002780671.1	functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria
YP_002780673.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
YP_002780674.1	in Escherichia coli transcription of this gene is enhanced by polyamines
YP_002780675.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
YP_002780676.1	binds the polymerase to DNA and acts as a sliding clamp
YP_002780677.1	similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate
YP_002780678.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
YP_002780683.1	negatively supercoils closed circular double-stranded DNA
YP_002780689.1	negatively supercoils closed circular double-stranded DNA
YP_002780700.1	integral membrane protein involved in inhibition of the Z-ring formation
YP_002780702.1	aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity
YP_002780703.1	protein synonym:protein kinase B
YP_002780704.1	protein synonym:protein kinase A
YP_002780706.1	protein synonym:rod shape-determining protein
YP_002780707.1	protein synonym:phosphoprotein phosphatase
YP_002780728.1	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate
YP_002780743.1	catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002780748.1	regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity
YP_002780754.1	protein synonym:biotin carboxylase/biotin carboxyl carrier protein
YP_002780756.1	protein synonym:carboxyltransferase
YP_002780759.1	protein synonym:acyl-CoA synthetase
YP_002780773.1	fragment
YP_002780783.1	fragment
YP_002780784.1	fragment
YP_002780807.1	acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate
YP_002780823.1	protein synonym:PHA depolymerase
YP_002780825.1	protein synonym:PHA polymerase; protein synonym:PHA synthase
YP_002780826.1	protein synonym:acyl-CoA synthetase
YP_002780831.1	protein synonym:quinone oxidoreductase
YP_002780840.1	catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate
YP_002780861.1	fragment
YP_002780862.1	fragment
YP_002780867.1	protein synonym:glutamate--ammonia ligase
YP_002780890.1	protein synonym:phosphotyrosine phosphatase
YP_002780905.1	fragment
YP_002780906.1	fragment
YP_002780927.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_002780928.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_002780944.1	protein synonym:acyl-CoA synthetase
YP_002780954.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis
YP_002781003.1	protein synonym:L-serine deaminase
YP_002781005.1	NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate
YP_002781008.1	activates fatty acids by binding to coenzyme A
YP_002781012.1	protein synonym:acyl-CoA thiolase
YP_002781019.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002781024.1	activates fatty acids by binding to coenzyme A
YP_002781028.1	activates fatty acids by binding to coenzyme A
YP_002781030.1	protein synonym:adenylyl cyclase
YP_002781040.1	catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002781056.1	protein synonym:Rieske [2Fe-2S] family protein
YP_002781081.1	catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia
YP_002781084.1	protein synonym:protein-methionine-S-oxide reductase
YP_002781096.1	protein synonym:non-heme ferritin
YP_002781098.1	protein synonym:non-heme ferritin
YP_002781103.1	catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis
YP_002781112.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002781126.1	catalyzes the formation of decaprenylphosphoryl-5-phosphoribose from phosphoribose diphosphate and decaprenyl phosphate
YP_002781134.1	activates fatty acids by binding to coenzyme A
YP_002781135.1	protein synonym:type I polyketide synthase
YP_002781136.1	protein synonym:carboxyltransferase
YP_002781151.1	protein synonym:dTDP-4-keto-6-deoxyglucose epimerase
YP_002781152.1	protein synonym:dTDP-glucose pyrophosphorylase; protein synonym:dTDP-glucose synthase
YP_002781167.1	EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity
YP_002781261.1	protein synonym:5-keto-D-gluconate 5-reductase
YP_002781272.1	protein synonym:very short patch repair protein
YP_002781273.1	protein synonym:cytosine-specific DNA methyltransferase
YP_002781276.1	catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate
YP_002781294.1	protein synonym:guanine insertion enzyme; protein synonym:queuine tRNA-ribosyltransferase
YP_002781299.1	this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu
YP_002781314.1	with FepCDG is involved in the transport of ferric enterobactin
YP_002781318.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA
YP_002781323.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002781324.1	multifunctional protein
YP_002781326.1	protein synonym:cyclopropane-fatty-acyl- phospholipid synthase
YP_002781330.1	involved in a recombinational process of DNA repair, independent of the recBC complex
YP_002781343.1	protein synonym:alpha-isopropylmalate synthase
YP_002781352.1	protein synonym:gamma-glutamyltransferase
YP_002781360.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002781366.1	Catalyzes the reversible phosphorolysis of 5'-deoxy-5'- methylthioadenosine (MTA) to adenine and 5-methylthio-D-ribose-1- phosphate
YP_002781383.1	protein synonym:glucose kinase
YP_002781397.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
YP_002781398.1	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde
YP_002781425.1	protein synonym:DNA-(apurinic or apyrimidinic site) lyase
YP_002781434.1	Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA
YP_002781450.1	protein synonym:beta-ketoadipate--succinyl-CoA transferase
YP_002781451.1	protein synonym:beta-ketoadipate--succinyl-CoA transferase
YP_002781455.1	catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
YP_002781456.1	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA
YP_002781474.1	protein synonym:gamma-glutamyltransferase
YP_002781487.1	catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate
YP_002781500.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002781504.1	protein synonym:sulfite--UDP-glucose sulfotransferase
YP_002781509.1	protein synonym:DD-peptidase
YP_002781515.1	protein synonym:cell division protein
YP_002781516.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_002781519.1	protein synonym:7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase
YP_002781523.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
YP_002781524.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
YP_002781528.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
YP_002781534.1	protein synonym:osmotically inducible protein C
YP_002781560.1	protein synonym:L-asparagine amidohydrolase
YP_002781562.1	catalyzes the formation of fumarate from aspartate
YP_002781565.1	non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair
YP_002781567.1	Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
YP_002781570.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
YP_002781571.1	catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate
YP_002781572.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
YP_002781583.1	catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation
YP_002781588.1	protein synonym:3-ketoacyl-ACP reductase
YP_002781589.1	protein synonym:Rieske [2Fe-2S] family protein
YP_002781601.1	protein synonym:trehalose-6-phosphate phosphatase
YP_002781620.1	catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway.
YP_002781621.1	protein synonym:urate oxidase
YP_002781628.1	catalyzes the formation of S-ureidoglycolate and urea from allantoate
YP_002781631.1	catalyzes the formation of L-tryptophan from indole and L-serine
YP_002781639.1	initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione
YP_002781641.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_002781642.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_002781645.1	protein synonym:terminal oxygenase
YP_002781651.1	protein synonym:GABA transaminase
YP_002781662.1	catalyzes the formation of fumarate from aspartate
YP_002781663.1	catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
YP_002781671.1	protein synonym:maltose alpha-D-glucosyltransferase
YP_002781689.1	catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA
YP_002781695.1	protein synonym:ATP-AMP transphosphorylase
YP_002781731.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002781732.1	protein synonym:acyl-CoA synthetase
YP_002781736.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002781737.1	protein synonym:reverse transcriptase
YP_002781759.1	protein synonym:benzyl alcohol dehydrogenase
YP_002781766.1	protein synonym:acyl-CoA synthetase
YP_002781770.1	protein synonym:acetyl-CoA synthetase
YP_002781774.1	protein synonym:3-ketoacyl-ACP reductase
YP_002781775.1	protein synonym:acyl-CoA thiolase
YP_002781779.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
YP_002781786.1	fragment
YP_002781787.1	fragment
YP_002781788.1	fragment
YP_002781804.1	protein synonym:quinone oxidoreductase
YP_002781810.1	AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase
YP_002781811.1	protein synonym:phenol hydroxylase
YP_002781829.1	fragment
YP_002781830.1	fragment
YP_002781843.1	protein synonym:acyl-CoA thiolase
YP_002781851.1	protein synonym:3-ketoacyl-ACP reductase
YP_002781852.1	bifunctional protein; protein synonym:riboflavin biosynthesis protein RibA
YP_002781873.1	protein synonym:acyl-CoA synthetase
YP_002781886.1	protein synonym:benzyl alcohol dehydrogenase
YP_002781903.1	protein synonym:4-(phosphohydroxy)-L-threonine dehydrogenase
YP_002781910.1	protein synonym:sedoheptulose 7-phosphate isomerase
YP_002781915.1	catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate
YP_002781919.1	protein synonym:hydroxypyruvate reductase
YP_002781929.1	catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate
YP_002781930.1	catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway
YP_002781931.1	catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism
YP_002781942.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002781954.1	protein synonym:oxalosuccinate decarboxylase
YP_002781962.1	protein synonym:CYP51; protein synonym:sterol 14-alpha demethylase
YP_002781966.1	activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence
YP_002781969.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002781974.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002781979.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002781980.1	activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence
YP_002781982.1	activates fatty acids by binding to coenzyme A
YP_002781986.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002781998.1	protein synonym:trehalose-6-phosphate synthase
YP_002782006.1	protein synonym:L-ornithine 5-monooxygenase
YP_002782020.1	fragment
YP_002782021.1	fragment
YP_002782035.1	protein synonym:acyl-CoA thiolase
YP_002782059.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
YP_002782063.1	catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate
YP_002782070.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
YP_002782083.1	protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters
YP_002782089.1	multifunctional protein
YP_002782094.1	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
YP_002782095.1	protein synonym:oligopeptidase B
YP_002782103.1	protein synonym:formylglycinamide ribonucleotide amidotransferase
YP_002782104.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_002782106.1	protein synonym:amylomaltase
YP_002782110.1	catalyzes the removal of amino acids from the N termini of peptides
YP_002782111.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
YP_002782115.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
YP_002782116.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
YP_002782121.1	catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate
YP_002782130.1	protein synonym:rhodanese
YP_002782135.1	protein synonym:acetyl-CoA--1D-myo-inosityl 2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside acetyltransferase; protein synonym:mycothiol synthase
YP_002782139.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
YP_002782143.1	protein synonym:steroyl-ACP desaturase
YP_002782147.1	protein synonym:benzyl alcohol dehydrogenase
YP_002782167.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002782190.1	catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive
YP_002782200.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription
YP_002782234.1	protein synonym:CO dehydrogenase
YP_002782235.1	protein synonym:CO dehydrogenase
YP_002782236.1	protein synonym:CO dehydrogenase
YP_002782245.1	catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate
YP_002782246.1	forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle
YP_002782247.1	catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate
YP_002782249.1	protein synonym:mutarotase
YP_002782250.1	type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH
YP_002782255.1	protein synonym:DNA photolyase; protein synonym:photoreactivating enzyme
YP_002782258.1	protein synonym:propionyl-CoA synthetase
YP_002782265.1	protein synonym:carboxyltransferase
YP_002782289.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002782304.1	catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA and has been shown to have polymerase activity
YP_002782318.1	protein synonym:acyl-CoA thiolase
YP_002782323.1	catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
YP_002782337.1	protein synonym:adenylyl cyclase
YP_002782340.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_002782345.1	involved in the biosynthesis of phosphatidylinositol mannosides (PIMs); the enzyme from Mycobacterium tuberculosis can phosphorylate a variety of amphipathic lipids
YP_002782352.1	converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA
YP_002782357.1	3'-5' exonuclease of DNA polymerase III
YP_002782360.1	catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; in mycobacteria LigC has weak intrinsic nick joining activities and is not essential for growth
YP_002782363.1	fragment
YP_002782364.1	fragment
YP_002782407.1	protein synonym:alpha-isopropylmalate synthase
YP_002782410.1	protein synonym:adenylyl cyclase
YP_002782418.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
YP_002782422.1	catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP
YP_002782441.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002782442.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002782448.1	FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
YP_002782469.1	protein synonym:CO dehydrogenase
YP_002782470.1	protein synonym:CO dehydrogenase
YP_002782471.1	protein synonym:CO dehydrogenase
YP_002782490.1	fragment
YP_002782494.1	protein synonym:acetoacetyl-CoA thiolase
YP_002782511.1	bifunctional protein
YP_002782513.1	protein synonym:2,3-butanediol dehydrogenase
YP_002782526.1	protein synonym:isopropylmalate isomerase
YP_002782527.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_002782555.1	protein synonym:Rieske [2Fe-2S] family protein
YP_002782556.1	fragment
YP_002782557.1	fragment
YP_002782563.1	fragment
YP_002782565.1	involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer
YP_002782575.1	protein synonym:CYP116
YP_002782582.1	fragment
YP_002782583.1	fragment
YP_002782584.1	protein synonym:acetoacetyl-CoA thiolase
YP_002782597.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_002782598.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_002782634.1	Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis
YP_002782647.1	bifunctional protein
YP_002782649.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_002782684.1	catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation
YP_002782716.1	protein synonym:phosphotyrosine phosphatase
YP_002782726.1	broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor
YP_002782750.1	fragment
YP_002782751.1	fragment
YP_002782753.1	protein synonym:galactose kinase
YP_002782754.1	protein synonym:UDP-glucose--hexose-1-phosphate uridylyltransferase
YP_002782764.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
YP_002782765.1	protein synonym:nucleotide exchange factor
YP_002782766.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_002782767.1	protein synonym:transcriptional regulator
YP_002782775.1	activates fatty acids by binding to coenzyme A
YP_002782784.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
YP_002782803.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate
YP_002782813.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
YP_002782815.1	protein synonym:O6-methylguanine-DNA alkyltransferase
YP_002782828.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
YP_002782834.1	catalyzes the interconversion of succinyl-CoA and succinate
YP_002782835.1	Catalyzes the only substrate-level phosphorylation in the TCA cycle
YP_002782839.1	glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate
YP_002782840.1	involved in de novo purine biosynthesis
YP_002782854.1	catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine
YP_002782855.1	catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate
YP_002782870.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
YP_002782871.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
YP_002782872.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
YP_002782873.1	required for 70S ribosome assembly
YP_002782875.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
YP_002782889.1	protein synonym:UDP-glucose pyrophosphorylase
YP_002782896.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_002782903.1	PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA
YP_002782908.1	catalyzes the degradation of arginine to citruline and ammonia
YP_002782917.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
YP_002782919.1	protein synonym:DNase
YP_002782925.1	catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
YP_002782930.1	UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter
YP_002782932.1	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits
YP_002782937.1	catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis
YP_002782952.1	catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate
YP_002782953.1	protein synonym:RF-3
YP_002782954.1	activates fatty acids by binding to coenzyme A
YP_002782955.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
YP_002782956.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
YP_002782961.1	protein synonym:gamma-glutamylcysteine synthetase
YP_002782980.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
YP_002782981.1	forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
YP_002782984.1	catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate
YP_002782998.1	protein synonym:dTDP-4-keto-6-deoxyglucose epimerase
YP_002783009.1	protein synonym:4'-phosphopantetheinyl transferase AcpS; protein synonym:holo-ACP synthase
YP_002783010.1	Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides
YP_002783017.1	functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era
YP_002783033.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
YP_002783051.1	initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione
YP_002783053.1	catalyzes the formation of acetyl-CoA from acetalaldehyde
YP_002783054.1	catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate
YP_002783061.1	fragment
YP_002783062.1	fragment
YP_002783065.1	protein synonym:terminal oxygenase
YP_002783067.1	protein synonym:3-oxosteroid 1-dehydrogenase
YP_002783069.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002783074.1	protein synonym:acyl-CoA synthetase
YP_002783076.1	activates fatty acids by binding to coenzyme A
YP_002783087.1	protein synonym:oxygenase reductase
YP_002783094.1	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
YP_002783098.1	catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine
YP_002783099.1	catalyzes the formation of 2-oxobutanoate from L-threonine
YP_002783104.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YP_002783111.1	catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis
YP_002783113.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
YP_002783117.1	protein synonym:steroyl-ACP desaturase
YP_002783118.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
YP_002783119.1	type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese
YP_002783121.1	protein synonym:exonuclease VII
YP_002783122.1	bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
YP_002783124.1	catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway
YP_002783133.1	translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
YP_002783141.1	protein synonym:EF-G
YP_002783146.1	molecular chaperone
YP_002783148.1	protein synonym:mismatch-specific uracil DNA-glycosylase
YP_002783153.1	protein synonym:fumarase
YP_002783163.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783164.1	The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen
YP_002783165.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783166.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783167.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783169.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783170.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783171.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783172.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783173.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783174.1	Catalyzes the transfer of electrons from NADH to ubiquinone
YP_002783175.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783176.1	Catalyzes the transfer of electrons from NADH to quinone
YP_002783182.1	involved in the fifth mannose transfer of phosphatidylinositol mannoside synthesis
YP_002783183.1	4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction
YP_002783198.1	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis
YP_002783201.1	catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis
YP_002783208.1	activates fatty acids by binding to coenzyme A
YP_002783216.1	catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate
YP_002783219.1	activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization
YP_002783227.1	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate
YP_002783232.1	mediates the export of protein precursors bearing twin-arginine signal peptides
YP_002783252.1	protein synonym:malic enzyme
YP_002783263.1	kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth
YP_002783277.1	protein synonym:acyl-CoA synthetase
YP_002783278.1	protein synonym:adenosine aminohydrolase
YP_002783285.1	protein synonym:acyl-CoA synthetase
YP_002783289.1	protein synonym:cold-shock DEAD-box protein A
YP_002783292.1	protein synonym:maltose alpha-D-glucosyltransferase
YP_002783297.1	protein synonym:acyl-CoA synthetase
YP_002783307.1	protein synonym:oxygenase reductase
YP_002783325.1	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
YP_002783335.1	catalyzes the formation of acetaldehyde from ethanolamine
YP_002783338.1	protein synonym:acyl-CoA synthetase
YP_002783344.1	protein synonym:carboxyltransferase
YP_002783345.1	protein synonym:biotin carboxylase/biotin carboxyl carrier protein
YP_002783349.1	AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase
YP_002783363.1	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA
YP_002783364.1	activates fatty acids by binding to coenzyme A
YP_002783377.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
YP_002783378.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
YP_002783379.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
YP_002783380.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
YP_002783381.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
YP_002783382.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YP_002783383.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
YP_002783384.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
YP_002783385.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
YP_002783386.1	one of the stabilizing components for the large ribosomal subunit
YP_002783387.1	primary binding protein; helps mediate assembly; involved in translation fidelity
YP_002783388.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
YP_002783389.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
YP_002783390.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
YP_002783391.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif
YP_002783392.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YP_002783393.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
YP_002783394.1	binds 5S rRNA along with protein L5 and L25
YP_002783395.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
YP_002783396.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
YP_002783397.1	late assembly protein
YP_002783398.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
YP_002783399.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
YP_002783400.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
YP_002783401.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
YP_002783402.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
YP_002783403.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
YP_002783404.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
YP_002783405.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
YP_002783406.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
YP_002783407.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
YP_002783408.1	is a component of the macrolide binding site in the peptidyl transferase center
YP_002783409.1	protein synonym:pseudouridine synthase I
YP_002783421.1	protein synonym:ornithine--oxo-acid aminotransferase
YP_002783422.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
YP_002783423.1	forms a direct contact with the tRNA during translation
YP_002783424.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YP_002783429.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_002783432.1	converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer
YP_002783437.1	in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
YP_002783441.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
YP_002783442.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth
YP_002783444.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in M. bovis this protein has been shown to be involved in expression of antigenic proteins
YP_002783448.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this protein is involved in expression of ribosome-associated gene products in stationary phase
YP_002783451.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_002783452.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_002783454.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
YP_002783468.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_002783478.1	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.
YP_002783480.1	protein synonym:rhodanese-like protein
YP_002783485.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
YP_002783487.1	Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine
YP_002783488.1	catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
YP_002783489.1	Converts isocitrate to alpha ketoglutarate
YP_002783492.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002783494.1	protein synonym:DD-peptidase
YP_002783495.1	catalyzes the oxidation of malate to oxaloacetate
YP_002783496.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
YP_002783497.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol
YP_002783500.1	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis
YP_002783501.1	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
YP_002783502.1	catalyzes the formation of inosine from adenosine
YP_002783508.1	protein synonym:UMP pyrophosphorylase
YP_002783509.1	protein synonym:glucose phosphomutase
YP_002783510.1	catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation
YP_002783515.1	catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity
YP_002783532.1	catalyzes the formation of 2-aminoadipate 6-semiladehyde and glutamate from lysine and 2-oxoglutarate
YP_002783533.1	protein synonym:phosphotyrosine phosphatase
YP_002783537.1	protein synonym:biotin carboxylase/biotin carboxyl carrier protein
YP_002783540.1	protein synonym:rhodanese
YP_002783544.1	fragment
YP_002783545.1	fragment
YP_002783546.1	Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell
YP_002783548.1	protein synonym:carboxyltransferase
YP_002783549.1	protein synonym:biotin-[acetyl-CoA carboxylase] holoenzyme synthetase
YP_002783555.1	With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
YP_002783563.1	protein synonym:GDP-mannose pyrophosphorylase
YP_002783565.1	catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0)
YP_002783566.1	catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO)
YP_002783570.1	converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells
YP_002783572.1	protein synonym:phosphomannose isomerase
YP_002783575.1	catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine
YP_002783576.1	catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
YP_002783582.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
YP_002783588.1	protein synonym:steroyl-CoA delta(9)-desaturase
YP_002783589.1	protein synonym:steroyl-CoA delta(9)-desaturase
YP_002783591.1	catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
YP_002783594.1	Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response
YP_002783614.1	The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation
YP_002783621.1	catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane
YP_002783633.1	can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates
YP_002783645.1	activates fatty acids by binding to coenzyme A
YP_002783651.1	protein synonym:histidinol-phosphatase
YP_002783653.1	recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1
YP_002783658.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
YP_002783661.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
YP_002783662.1	catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate
YP_002783672.1	protein synonym:molybdenum cofactor biosynthesis protein
YP_002783673.1	MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis
YP_002783674.1	protein synonym:molybdenum cofactor biosynthesis protein
YP_002783675.1	together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z
YP_002783676.1	protein synonym:molybdenum cofactor biosynthesis protein
YP_002783678.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
YP_002783679.1	Catalyzes hydrolysis of n-ribosyl-purine into a purine and d-ribose
YP_002783684.1	protein synonym:glutaredoxin-like protein
YP_002783685.1	in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF
YP_002783686.1	Catalyzes the rate-limiting step in dNTP synthesis
YP_002783687.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
YP_002783692.1	protein synonym:O-phosphoserine phosphohydrolase
YP_002783712.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
YP_002783714.1	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB
YP_002783718.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
YP_002783719.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_002783724.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
YP_002783725.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
YP_002783729.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
YP_002783731.1	acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate
YP_002783732.1	with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit
YP_002783733.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
YP_002783734.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
YP_002783738.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
YP_002783742.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
YP_002783743.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
YP_002783744.1	protein synonym:histone-like protein
YP_002783745.1	protein synonym:8-oxo-dGTPase; protein synonym:antimutator
YP_002783746.1	catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate
YP_002783748.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
YP_002783749.1	catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine
YP_002783750.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
YP_002783753.1	catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP
YP_002783755.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YP_002783757.1	required for 70S ribosome assembly
YP_002783759.1	catalyzes branch migration in Holliday junction intermediates
YP_002783760.1	biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate
YP_002783762.1	Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
YP_002783765.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
YP_002783766.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
YP_002783767.1	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases
YP_002783771.1	catalyzes the hydrolysis of acylphosphate
YP_002783775.1	protein synonym:signal transduction protein
YP_002783776.1	catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; also involved in adenylylating and deadelnylyating GlnK
YP_002783779.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
YP_002783781.1	Essential for efficient processing of 16S rRNA
YP_002783782.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
YP_002783786.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
YP_002783787.1	protein synonym:leader peptidase I
YP_002783788.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
YP_002783804.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
YP_002783805.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
YP_002783806.1	Catalyzes the phosphorylation of UMP to UDP
YP_002783807.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
YP_002783808.1	protein synonym:CDP-diacylglycerol synthase
YP_002783812.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
YP_002783814.1	catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate
YP_002783816.1	catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis
YP_002783824.1	protein synonym:acetyl-CoA synthetase
YP_002783830.1	protein synonym:peptidase M
YP_002783831.1	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
YP_002783837.1	catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide
YP_002783839.1	malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate
YP_002783842.1	catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide
YP_002783843.1	responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid
YP_002783845.1	multifunctional protein; protein synonym:precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase/uroporphyrin-III methyltransferase
YP_002783856.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
YP_002783872.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
YP_002783873.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
YP_002783875.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YP_002783877.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
YP_002783882.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
YP_002783884.1	catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities
YP_002783885.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
YP_002783886.1	bifunctional protein; protein synonym:polyribonucleotide nucleotidyltransferase
YP_002783909.1	fragment
YP_002783918.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
YP_002783924.1	flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor
YP_002783925.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
YP_002783928.1	protein synonym:DNA translocase
YP_002783931.1	catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis
YP_002783932.1	protein synonym:CDP-diacylglycerol--glycerol-3- phosphate 3-phosphatidyltransferase
YP_002783943.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
YP_002783944.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
YP_002783949.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
YP_002783953.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
YP_002783955.1	involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate
YP_002783959.1	protein synonym:histidine-containing protein
YP_002783960.1	protein synonym:PTS fructose-specific EIIABC component; protein synonym:protein-Npi-phosphohistidine-- sugar phosphotransferase
YP_002783961.1	protein synonym:fructose-1-phosphate kinase
YP_002783963.1	protein synonym:phosphotransferase system enzyme I
YP_002783966.1	Represses a number of genes involved in the response to DNA damage
YP_002783986.1	protein synonym:UDP-galactose 4-epimerase
YP_002783989.1	protein synonym:acetyl-CoA synthetase (ADP-forming)
YP_002783990.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase
YP_002784000.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YP_002784001.1	protein synonym:polyphosphate--glucose phosphotransferase
YP_002784002.1	protein synonym:inositol-phosphate phosphatase
YP_002784006.1	catalyzes the formation of dUMP from dUTP
YP_002784020.1	catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate
YP_002784029.1	multifunctional protein
YP_002784030.1	protein synonym:3-ketoacyl-CoA thiolase; protein synonym:fatty oxidation complex beta subunit
YP_002784035.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
YP_002784036.1	catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX
YP_002784049.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
YP_002784051.1	protein synonym:CDP-diacylglycerol--inositol 3-phosphatidyltransferase
YP_002784052.1	Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
YP_002784055.1	with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate
YP_002784056.1	protein synonym:thioesterase II
YP_002784058.1	protein synonym:thioesterase II
YP_002784059.1	with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate
YP_002784063.1	endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity
YP_002784064.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
YP_002784065.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
YP_002784067.1	part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane
YP_002784068.1	forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
YP_002784070.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
YP_002784071.1	bifunctional protein; protein synonym:(p)ppGpp synthetase/hydrolase
YP_002784075.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
YP_002784090.1	protein synonym:cyclopropane-fatty-acyl- phospholipid synthase
YP_002784102.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
YP_002784108.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
YP_002784109.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
YP_002784111.1	AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate
YP_002784113.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
YP_002784115.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
YP_002784118.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
YP_002784119.1	Regulates rRNA biosynthesis by transcriptional antitermination
YP_002784120.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
YP_002784121.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
YP_002784122.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
YP_002784124.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
YP_002784125.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
YP_002784126.1	protein synonym:OMP decarboxylase
YP_002784128.1	Essential for recycling GMP and indirectly, cGMP
YP_002784130.1	catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine
YP_002784131.1	catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
YP_002784132.1	binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity
YP_002784136.1	modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth
YP_002784140.1	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate
YP_002784141.1	bifunctional protein; protein synonym:riboflavin biosynthesis protein RibG
YP_002784142.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
YP_002784143.1	bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate
YP_002784144.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
YP_002784146.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
YP_002784151.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
YP_002784152.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
YP_002784154.1	catalyzes the formation of oxaloacetate from phosphoenolpyruvate
YP_002784157.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
YP_002784158.1	catalyzes the reversible formation of D-erythrose 4-phosphate and D-fructose 6-phosphate from sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate
YP_002784159.1	catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase
YP_002784160.1	converts protoheme IX and farnesyl diphosphate to heme O
YP_002784161.1	protein synonym:quinone oxidoreductase
YP_002784178.1	protein synonym:ABC-type ATPase
YP_002784179.1	bifunctional protein
YP_002784187.1	Catalyzes the conversion of citrate to isocitrate
YP_002784193.1	protein synonym:3-ketoacyl-ACP reductase
YP_002784194.1	Catalyzes a key regulatory step in fatty acid biosynthesis
YP_002784195.1	protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
YP_002784203.1	fragment
YP_002784204.1	fragment
YP_002784210.1	MDM; functions in conversion of succinate to propionate
YP_002784211.1	functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins
YP_002784219.1	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
YP_002784222.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
YP_002784245.1	protein synonym:GABA permease
YP_002784266.1	fragment
YP_002784267.1	fragment
YP_002784268.1	fragment
YP_002784286.1	catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family
YP_002784289.1	catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate
YP_002784309.1	fragment
YP_002784310.1	fragment
YP_002784332.1	protein synonym:acyl-CoA synthetase
YP_002784352.1	protein synonym:phosphotyrosine phosphatase
YP_002784365.1	protein synonym:acyl-CoA synthetase
YP_002784366.1	bifunctional protein; protein synonym:acyl-CoA synthetase
YP_002784368.1	protein synonym:acyl-CoA thiolase
YP_002784371.1	catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin
YP_002784383.1	fragment
YP_002784385.1	fragment
YP_002784404.1	protein synonym:acyl-CoA synthetase
YP_002784410.1	fragment
YP_002784411.1	fragment
YP_002784412.1	fragment
YP_002784418.1	acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate
YP_002784419.1	fragment
YP_002784420.1	fragment
YP_002784421.1	fragment
YP_002784422.1	fragment
YP_002784424.1	fragment
YP_002784425.1	fragment
YP_002784426.1	fragment
YP_002784429.1	fragment
YP_002784434.1	fragment
YP_002784439.1	fragment
YP_002784442.1	fragment
YP_002784508.1	protein synonym:18-kDa antigen
YP_002784523.1	protein synonym:GDP-4-keto-6-deoxy-D-mannose-3,5- epimerase-4-reductase