-- dump date   	20140620_033402
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1105110000001	hypothetical protein; Provisional; Region: PRK09956
1105110000002	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105110000003	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105110000004	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105110000005	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105110000006	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105110000007	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105110000008	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105110000009	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1105110000010	ParA-like protein; Provisional; Region: PHA02518
1105110000011	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105110000012	P-loop; other site
1105110000013	Magnesium ion binding site [ion binding]; other site
1105110000014	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105110000015	potential frameshift: common BLAST hit: gi|332290602|ref|YP_004421446.1| patatin-like phospholipase
1105110000016	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1105110000017	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1105110000018	catalytic residues [active]
1105110000019	catalytic nucleophile [active]
1105110000020	Presynaptic Site I dimer interface [polypeptide binding]; other site
1105110000021	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1105110000022	Synaptic Flat tetramer interface [polypeptide binding]; other site
1105110000023	Synaptic Site I dimer interface [polypeptide binding]; other site
1105110000024	DNA binding site [nucleotide binding]
1105110000025	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1105110000026	DNA-binding interface [nucleotide binding]; DNA binding site
1105110000027	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1105110000028	Predicted ATPase [General function prediction only]; Region: COG3911
1105110000029	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1105110000030	WGR domain; Region: WGR; cl01581
1105110000031	Conjugal transfer protein TraD; Region: TraD; pfam06412
1105110000032	MobA/MobL family; Region: MobA_MobL; pfam03389
1105110000033	AAA domain; Region: AAA_30; pfam13604
1105110000034	Toprim domain; Region: Toprim_4; pfam13662
1105110000035	active site
1105110000036	metal binding site [ion binding]; metal-binding site
1105110000037	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1105110000038	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1105110000039	Protein export membrane protein; Region: SecD_SecF; pfam02355
1105110000040	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3750
1105110000041	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1105110000042	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1105110000043	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
1105110000044	propionate/acetate kinase; Provisional; Region: PRK12379
1105110000045	phosphate acetyltransferase; Provisional; Region: PRK11890
1105110000046	bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated; Region: PRK08190
1105110000047	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1105110000048	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105110000049	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105110000050	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105110000051	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105110000052	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105110000053	type IV secretion system ATPase VirB4; Provisional; Region: PRK13898
1105110000054	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1105110000055	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110000056	Walker A/P-loop; other site
1105110000057	ATP binding site [chemical binding]; other site
1105110000058	type IV secretion system protein VirB3; Provisional; Region: PRK13899
1105110000059	potential frameshift: common BLAST hit: gi|350273155|ref|YP_004884468.1| acetylglutamate kinase
1105110000060	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1105110000061	G1 box; other site
1105110000062	GTP/Mg2+ binding site [chemical binding]; other site
1105110000063	Switch I region; other site
1105110000064	G2 box; other site
1105110000065	G3 box; other site
1105110000066	Switch II region; other site
1105110000067	G4 box; other site
1105110000068	G5 box; other site
1105110000069	50S ribosomal protein L31; Provisional; Region: PRK01397
1105110000070	Ribosomal protein L28 [Translation, ribosomal structure and biogenesis]; Region: RpmB; COG0227
1105110000071	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110000072	Q-loop/lid; other site
1105110000073	ABC transporter signature motif; other site
1105110000074	Walker B; other site
1105110000075	D-loop; other site
1105110000076	H-loop/switch region; other site
1105110000077	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110000078	Walker A/P-loop; other site
1105110000079	ATP binding site [chemical binding]; other site
1105110000080	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1105110000081	Permease; Region: Permease; pfam02405
1105110000082	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
1105110000083	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1105110000084	active site
1105110000085	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1105110000086	dimer interface [polypeptide binding]; other site
1105110000087	substrate binding site [chemical binding]; other site
1105110000088	catalytic residues [active]
1105110000089	potential frameshift: common BLAST hit: gi|67458470|ref|YP_246094.1| ribose-phosphate pyrophosphokinase
1105110000090	potential frameshift: common BLAST hit: gi|157964158|ref|YP_001498982.1| ribose-phosphate pyrophosphokinase
1105110000091	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110000092	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1105110000093	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1105110000094	FMN binding site [chemical binding]; other site
1105110000095	active site
1105110000096	catalytic residues [active]
1105110000097	substrate binding site [chemical binding]; other site
1105110000098	Putative catalytic NodB homology domain of uncharacterized protein RC0012 from Rickettsia conorii and its bacterial homologs; Region: CE4_RC0012_like; cd10963
1105110000099	NodB motif; other site
1105110000100	putative active site [active]
1105110000101	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1105110000102	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1105110000103	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1105110000104	intersubunit interface [polypeptide binding]; other site
1105110000105	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
1105110000106	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1105110000107	active site
1105110000108	NTP binding site [chemical binding]; other site
1105110000109	metal binding triad [ion binding]; metal-binding site
1105110000110	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1105110000111	potential frameshift: common BLAST hit: gi|67458412|ref|YP_246036.1| ComEC/Rec2-like protein
1105110000112	potential frameshift: common BLAST hit: gi|67458412|ref|YP_246036.1| ComEC/Rec2-like protein
1105110000113	potential frameshift: common BLAST hit: gi|91204982|ref|YP_537337.1| ComEC/Rec2 family protein
1105110000114	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105110000115	F0F1 ATP synthase subunit B; Validated; Region: PRK06568
1105110000116	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1105110000117	F0F1 ATP synthase subunit B'; Validated; Region: PRK06569
1105110000118	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1105110000119	F0F1 ATP synthase subunit C; Validated; Region: PRK07558
1105110000120	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105110000121	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1105110000122	ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Region: ATP_synt_6_or_A; TIGR01131
1105110000123	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5336
1105110000124	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1105110000125	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
1105110000126	catalytic residues [active]
1105110000127	Transcriptional regulators, similar to M. xanthus CarD [Transcription]; Region: COG1329
1105110000128	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105110000129	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110000130	S-adenosylmethionine binding site [chemical binding]; other site
1105110000131	Predicted regulatory domain of a methyltransferase [General function prediction only]; Region: COG4797
1105110000132	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1105110000133	Recombinational DNA repair ATPase (RecF pathway) [DNA replication, recombination, and repair]; Region: RecF; COG1195
1105110000134	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110000135	Walker A/P-loop; other site
1105110000136	ATP binding site [chemical binding]; other site
1105110000137	Q-loop/lid; other site
1105110000138	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110000139	ABC transporter signature motif; other site
1105110000140	Walker B; other site
1105110000141	D-loop; other site
1105110000142	H-loop/switch region; other site
1105110000143	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
1105110000144	potential frameshift: common BLAST hit: gi|165932594|ref|YP_001649383.1| dihydrofolate reductase
1105110000145	potential frameshift: common BLAST hit: gi|67458431|ref|YP_246055.1| folate synthesis bifunctional protein
1105110000146	potential frameshift: common BLAST hit: gi|67458431|ref|YP_246055.1| folate synthesis bifunctional protein
1105110000147	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1105110000148	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1105110000149	Putative transcriptional regulator [Transcription]; Region: COG1678
1105110000150	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1105110000151	Colicin V production protein; Region: Colicin_V; pfam02674
1105110000152	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110000153	potential frameshift: common BLAST hit: gi|67458439|ref|YP_246063.1| cell surface antigen-like protein Sca10
1105110000154	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1105110000155	Protein of unknown function (DUF2748); Region: DUF2748; pfam10871
1105110000156	acetoacetyl-CoA reductase; Provisional; Region: PRK12824
1105110000157	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1105110000158	NAD(P) binding site [chemical binding]; other site
1105110000159	homotetramer interface [polypeptide binding]; other site
1105110000160	homodimer interface [polypeptide binding]; other site
1105110000161	active site
1105110000162	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110000163	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1105110000164	Clp amino terminal domain; Region: Clp_N; pfam02861
1105110000165	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110000166	Walker A motif; other site
1105110000167	ATP binding site [chemical binding]; other site
1105110000168	Walker B motif; other site
1105110000169	arginine finger; other site
1105110000170	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110000171	Walker A motif; other site
1105110000172	ATP binding site [chemical binding]; other site
1105110000173	Walker B motif; other site
1105110000174	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1105110000175	UGMP family protein; Validated; Region: PRK09604
1105110000176	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1105110000177	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105110000178	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
1105110000179	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1105110000180	Di-iron ligands [ion binding]; other site
1105110000181	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
1105110000182	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110000183	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1105110000184	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1105110000185	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1105110000186	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1105110000187	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1105110000188	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1105110000189	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1105110000190	Ligand Binding Site [chemical binding]; other site
1105110000191	FtsH Extracellular; Region: FtsH_ext; pfam06480
1105110000192	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1105110000193	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110000194	Walker A motif; other site
1105110000195	ATP binding site [chemical binding]; other site
1105110000196	Walker B motif; other site
1105110000197	arginine finger; other site
1105110000198	Peptidase family M41; Region: Peptidase_M41; pfam01434
1105110000199	potential frameshift: common BLAST hit: gi|91206207|ref|YP_538562.1| site-specific DNA methylase
1105110000200	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1105110000201	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1105110000202	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1105110000203	Uncharacterized conserved protein [Function unknown]; Region: COG1565
1105110000204	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1105110000205	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1105110000206	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1105110000207	membrane protein insertase; Provisional; Region: PRK01318
1105110000208	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1105110000209	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1105110000210	Methyltransferase domain; Region: Methyltransf_11; pfam08241
1105110000211	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1105110000212	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1105110000213	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cl00234
1105110000214	active site
1105110000215	metal binding site [ion binding]; metal-binding site
1105110000216	catalytic residues [active]
1105110000217	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105110000218	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1105110000219	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110000220	putative substrate translocation pore; other site
1105110000221	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1105110000222	active site
1105110000223	multimer interface [polypeptide binding]; other site
1105110000224	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1105110000225	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1105110000226	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1105110000227	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1105110000228	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1105110000229	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1105110000230	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105110000231	P-loop; other site
1105110000232	Magnesium ion binding site [ion binding]; other site
1105110000233	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105110000234	Magnesium ion binding site [ion binding]; other site
1105110000235	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1105110000236	ParB-like nuclease domain; Region: ParB; smart00470
1105110000237	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1105110000238	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105110000239	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105110000240	ABC transporter; Region: ABC_tran_2; pfam12848
1105110000241	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105110000242	Protein of unknown function (DUF2672); Region: DUF2672; pfam10878
1105110000243	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1105110000244	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1105110000245	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1105110000246	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1105110000247	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
1105110000248	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1105110000249	Zn2+ binding site [ion binding]; other site
1105110000250	Mg2+ binding site [ion binding]; other site
1105110000251	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1105110000252	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1105110000253	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
1105110000254	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1105110000255	active site
1105110000256	HIGH motif; other site
1105110000257	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105110000258	KMSK motif region; other site
1105110000259	tRNA binding surface [nucleotide binding]; other site
1105110000260	DALR anticodon binding domain; Region: DALR_1; smart00836
1105110000261	anticodon binding site; other site
1105110000262	Sporulation related domain; Region: SPOR; pfam05036
1105110000263	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1105110000264	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1105110000265	CAP-like domain; other site
1105110000266	active site
1105110000267	primary dimer interface [polypeptide binding]; other site
1105110000268	Gram-negative porin; Region: Porin_4; pfam13609
1105110000269	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1105110000270	trimer interface [polypeptide binding]; other site
1105110000271	active site
1105110000272	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1105110000273	SecA binding site; other site
1105110000274	Preprotein binding site; other site
1105110000275	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1105110000276	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105110000277	active site
1105110000278	phosphorylation site [posttranslational modification]
1105110000279	intermolecular recognition site; other site
1105110000280	dimerization interface [polypeptide binding]; other site
1105110000281	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1105110000282	DNA binding site [nucleotide binding]
1105110000283	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1105110000284	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1105110000285	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1105110000286	Protein of unknown function (DUF1013); Region: DUF1013; cl11533
1105110000287	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
1105110000288	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1105110000289	Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047
1105110000290	EamA-like transporter family; Region: EamA; pfam00892
1105110000291	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1105110000292	EamA-like transporter family; Region: EamA; pfam00892
1105110000293	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110000294	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110000295	putative substrate translocation pore; other site
1105110000296	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
1105110000297	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
1105110000298	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105110000299	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1105110000300	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1105110000301	active site
1105110000302	HIGH motif; other site
1105110000303	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1105110000304	KMSKS motif; other site
1105110000305	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1105110000306	tRNA binding surface [nucleotide binding]; other site
1105110000307	anticodon binding site; other site
1105110000308	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1105110000309	rRNA interaction site [nucleotide binding]; other site
1105110000310	S8 interaction site; other site
1105110000311	putative laminin-1 binding site; other site
1105110000312	elongation factor Ts; Provisional; Region: tsf; PRK09377
1105110000313	UBA/TS-N domain; Region: UBA; pfam00627
1105110000314	Elongation factor TS; Region: EF_TS; pfam00889
1105110000315	Elongation factor TS; Region: EF_TS; pfam00889
1105110000316	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1105110000317	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1105110000318	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
1105110000319	putative acyl-acceptor binding pocket; other site
1105110000320	aspartate aminotransferase; Provisional; Region: PRK05764
1105110000321	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1105110000322	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105110000323	homodimer interface [polypeptide binding]; other site
1105110000324	catalytic residue [active]
1105110000325	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1105110000326	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105110000327	binding surface
1105110000328	TPR motif; other site
1105110000329	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1105110000330	Methyltransferase domain; Region: Methyltransf_18; pfam12847
1105110000331	Surface lipoprotein [Cell envelope biogenesis, outer membrane]; Region: VacJ; COG2853
1105110000332	ABC-type transport system involved in resistance to organic solvents, auxiliary component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2D; COG2854
1105110000333	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110000334	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1105110000335	active site
1105110000336	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1105110000337	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1105110000338	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1105110000339	trimer interface [polypeptide binding]; other site
1105110000340	active site
1105110000341	UDP-GlcNAc binding site [chemical binding]; other site
1105110000342	lipid binding site [chemical binding]; lipid-binding site
1105110000343	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1105110000344	Acyl-[acyl carrier protein]; Region: LpxA; COG1043
1105110000345	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1105110000346	active site
1105110000347	putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; Validated; Region: PRK06567
1105110000348	FAD/NAD binding domain (electron transfer subunit) of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate...; Region: DHOD_e_trans_like; cd06192
1105110000349	FAD binding pocket [chemical binding]; other site
1105110000350	FAD binding motif [chemical binding]; other site
1105110000351	phosphate binding motif [ion binding]; other site
1105110000352	beta-alpha-beta structure motif; other site
1105110000353	NAD binding pocket [chemical binding]; other site
1105110000354	Iron coordination center [ion binding]; other site
1105110000355	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1105110000356	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1105110000357	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1105110000358	Walker A/P-loop; other site
1105110000359	ATP binding site [chemical binding]; other site
1105110000360	Q-loop/lid; other site
1105110000361	ABC transporter signature motif; other site
1105110000362	Walker B; other site
1105110000363	D-loop; other site
1105110000364	H-loop/switch region; other site
1105110000365	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1105110000366	catalytic residues [active]
1105110000367	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1806
1105110000368	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1105110000369	substrate binding site [chemical binding]; other site
1105110000370	active site
1105110000371	ferrochelatase; Reviewed; Region: hemH; PRK00035
1105110000372	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1105110000373	C-terminal domain interface [polypeptide binding]; other site
1105110000374	active site
1105110000375	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1105110000376	active site
1105110000377	N-terminal domain interface [polypeptide binding]; other site
1105110000378	Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863
1105110000379	potential frameshift: common BLAST hit: gi|67459789|ref|YP_247413.1| prophage antirepressor
1105110000380	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1105110000381	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1105110000382	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110000383	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110000384	putative substrate translocation pore; other site
1105110000385	potential frameshift: common BLAST hit: gi|67458618|ref|YP_246242.1| ATPase
1105110000386	potential frameshift: common BLAST hit: gi|157827810|ref|YP_001496874.1| oxidoreductase
1105110000387	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4391
1105110000388	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1105110000389	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105110000390	ATP binding site [chemical binding]; other site
1105110000391	Mg2+ binding site [ion binding]; other site
1105110000392	G-X-G motif; other site
1105110000393	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1105110000394	ATP binding site [chemical binding]; other site
1105110000395	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1105110000396	ribosomal protein L33, bacterial type; Region: rpmG_bact; TIGR01023
1105110000397	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1105110000398	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1105110000399	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1105110000400	amidase catalytic site [active]
1105110000401	Zn binding residues [ion binding]; other site
1105110000402	substrate binding site [chemical binding]; other site
1105110000403	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1105110000404	lipoate-protein ligase B; Provisional; Region: PRK14347
1105110000405	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1105110000406	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cl00630
1105110000407	putative active site [active]
1105110000408	Na+/H+ antiporter [Inorganic ion transport and metabolism]; Region: NhaA; COG3004
1105110000409	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1105110000410	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1105110000411	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1105110000412	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1105110000413	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1105110000414	metal binding site [ion binding]; metal-binding site
1105110000415	dimer interface [polypeptide binding]; other site
1105110000416	DNA polymerase III chi subunit, HolC; Region: DNA_pol3_chi; cl01106
1105110000417	Predicted permeases [General function prediction only]; Region: COG0795
1105110000418	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1105110000419	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1105110000420	active site
1105110000421	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1105110000422	putative hydrolase; Provisional; Region: PRK02113
1105110000423	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1105110000424	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110000425	Walker A/P-loop; other site
1105110000426	ATP binding site [chemical binding]; other site
1105110000427	Q-loop/lid; other site
1105110000428	ABC transporter signature motif; other site
1105110000429	Walker B; other site
1105110000430	D-loop; other site
1105110000431	H-loop/switch region; other site
1105110000432	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1105110000433	Beta-lactamase; Region: Beta-lactamase; cl17358
1105110000434	Predicted aspartyl protease [General function prediction only]; Region: COG3577
1105110000435	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
1105110000436	catalytic motif [active]
1105110000437	Catalytic residue [active]
1105110000438	hypothetical protein; Validated; Region: PRK00153
1105110000439	DNA polymerase III subunits gamma and tau; Validated; Region: PRK06645
1105110000440	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110000441	Walker A motif; other site
1105110000442	ATP binding site [chemical binding]; other site
1105110000443	Walker B motif; other site
1105110000444	arginine finger; other site
1105110000445	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1105110000446	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
1105110000447	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
1105110000448	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1105110000449	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
1105110000450	ligand binding site [chemical binding]; other site
1105110000451	homodimer interface [polypeptide binding]; other site
1105110000452	NAD(P) binding site [chemical binding]; other site
1105110000453	trimer interface B [polypeptide binding]; other site
1105110000454	trimer interface A [polypeptide binding]; other site
1105110000455	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
1105110000456	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1105110000457	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1105110000458	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1105110000459	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1105110000460	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110000461	Dolichol kinase [Lipid metabolism]; Region: SEC59; COG0170
1105110000462	DNA primase, catalytic core; Region: dnaG; TIGR01391
1105110000463	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1105110000464	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1105110000465	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1105110000466	active site
1105110000467	metal binding site [ion binding]; metal-binding site
1105110000468	interdomain interaction site; other site
1105110000469	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1105110000470	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1105110000471	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1105110000472	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1105110000473	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1105110000474	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1105110000475	DNA binding residues [nucleotide binding]
1105110000476	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1105110000477	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1105110000478	dimerization interface 3.5A [polypeptide binding]; other site
1105110000479	active site
1105110000480	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1105110000481	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1105110000482	motif 1; other site
1105110000483	active site
1105110000484	motif 2; other site
1105110000485	motif 3; other site
1105110000486	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1105110000487	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110000488	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110000489	putative substrate translocation pore; other site
1105110000490	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
1105110000491	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1105110000492	putative active site [active]
1105110000493	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
1105110000494	motif 1; other site
1105110000495	dimer interface [polypeptide binding]; other site
1105110000496	active site
1105110000497	motif 2; other site
1105110000498	motif 3; other site
1105110000499	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1105110000500	DALR anticodon binding domain; Region: DALR_1; pfam05746
1105110000501	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1105110000502	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1105110000503	Putative methyltransferase; Region: Methyltransf_4; cl17290
1105110000504	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1105110000505	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110000506	S-adenosylmethionine binding site [chemical binding]; other site
1105110000507	PemK-like protein; Region: PemK; pfam02452
1105110000508	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1105110000509	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1105110000510	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1105110000511	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105110000512	RNA binding surface [nucleotide binding]; other site
1105110000513	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1105110000514	active site
1105110000515	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
1105110000516	Fe-S cluster binding site [ion binding]; other site
1105110000517	active site
1105110000518	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
1105110000519	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
1105110000520	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1105110000521	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1105110000522	dimer interface [polypeptide binding]; other site
1105110000523	active site
1105110000524	citrylCoA binding site [chemical binding]; other site
1105110000525	NADH binding [chemical binding]; other site
1105110000526	cationic pore residues; other site
1105110000527	oxalacetate/citrate binding site [chemical binding]; other site
1105110000528	coenzyme A binding site [chemical binding]; other site
1105110000529	catalytic triad [active]
1105110000530	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1105110000531	GTP1/OBG; Region: GTP1_OBG; pfam01018
1105110000532	Obg GTPase; Region: Obg; cd01898
1105110000533	G1 box; other site
1105110000534	GTP/Mg2+ binding site [chemical binding]; other site
1105110000535	Switch I region; other site
1105110000536	G2 box; other site
1105110000537	G3 box; other site
1105110000538	Switch II region; other site
1105110000539	G4 box; other site
1105110000540	G5 box; other site
1105110000541	trigger factor; Provisional; Region: tig; PRK01490
1105110000542	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1105110000543	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1105110000544	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1105110000545	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1105110000546	substrate-cofactor binding pocket; other site
1105110000547	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105110000548	catalytic residue [active]
1105110000549	heat shock protein 90; Provisional; Region: PRK05218
1105110000550	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105110000551	ATP binding site [chemical binding]; other site
1105110000552	Mg2+ binding site [ion binding]; other site
1105110000553	G-X-G motif; other site
1105110000554	hypothetical protein; Reviewed; Region: PRK01530
1105110000555	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1105110000556	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110000557	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110000558	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1105110000559	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1105110000560	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1105110000561	dimer interface [polypeptide binding]; other site
1105110000562	ssDNA binding site [nucleotide binding]; other site
1105110000563	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1105110000564	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1105110000565	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1105110000566	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1105110000567	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1105110000568	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1105110000569	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1105110000570	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1105110000571	Surface antigen [Cell envelope biogenesis, outer membrane]; Region: LipA; COG4520
1105110000572	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1105110000573	Cation efflux family; Region: Cation_efflux; cl00316
1105110000574	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1105110000575	nucleoside/Zn binding site; other site
1105110000576	dimer interface [polypeptide binding]; other site
1105110000577	catalytic motif [active]
1105110000578	heme exporter protein CcmC; Region: ccmC; TIGR01191
1105110000579	Ferredoxin [Energy production and conversion]; Region: COG1146
1105110000580	4Fe-4S binding domain; Region: Fer4; cl02805
1105110000581	Domain of unknown function (DUF3470); Region: DUF3470; pfam11953
1105110000582	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1105110000583	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1105110000584	Protein of unknown function (DUF721); Region: DUF721; pfam05258
1105110000585	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1105110000586	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
1105110000587	Mg++ binding site [ion binding]; other site
1105110000588	putative catalytic motif [active]
1105110000589	putative substrate binding site [chemical binding]; other site
1105110000590	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1105110000591	MPN+ (JAMM) motif; other site
1105110000592	Zinc-binding site [ion binding]; other site
1105110000593	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1105110000594	active site
1105110000595	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1105110000596	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1105110000597	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1105110000598	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1105110000599	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105110000600	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1105110000601	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1105110000602	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1105110000603	poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838
1105110000604	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167
1105110000605	Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170
1105110000606	PLD-like domain; Region: PLDc_2; pfam13091
1105110000607	putative active site [active]
1105110000608	catalytic site [active]
1105110000609	Phasin protein; Region: Phasin_2; pfam09361
1105110000610	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1105110000611	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1105110000612	active site
1105110000613	DNA binding site [nucleotide binding]
1105110000614	Int/Topo IB signature motif; other site
1105110000615	RNA polymerase-binding protein DksA; Region: dksA; TIGR02420
1105110000616	Maf-like protein; Region: Maf; pfam02545
1105110000617	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1105110000618	active site
1105110000619	dimer interface [polypeptide binding]; other site
1105110000620	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1105110000621	rRNA binding site [nucleotide binding]; other site
1105110000622	predicted 30S ribosome binding site; other site
1105110000623	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105110000624	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105110000625	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105110000626	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105110000627	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105110000628	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105110000629	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105110000630	non-specific DNA binding site [nucleotide binding]; other site
1105110000631	salt bridge; other site
1105110000632	sequence-specific DNA binding site [nucleotide binding]; other site
1105110000633	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
1105110000634	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
1105110000635	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1105110000636	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1105110000637	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1105110000638	TrkA-N domain; Region: TrkA_N; pfam02254
1105110000639	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3807
1105110000640	Bacterial SH3 domain; Region: SH3_4; pfam06347
1105110000641	Bacterial SH3 domain; Region: SH3_4; pfam06347
1105110000642	potential frameshift: common BLAST hit: gi|91204878|ref|YP_537233.1| nucleotidyltransferase
1105110000643	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1105110000644	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1105110000645	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105110000646	FeS/SAM binding site; other site
1105110000647	TRAM domain; Region: TRAM; pfam01938
1105110000648	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
1105110000649	Transglycosylase; Region: Transgly; pfam00912
1105110000650	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1105110000651	potential frameshift: common BLAST hit: gi|67459667|ref|YP_247291.1| Beta-lactamase class D
1105110000652	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1105110000653	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1105110000654	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1105110000655	dimerization interface [polypeptide binding]; other site
1105110000656	DPS ferroxidase diiron center [ion binding]; other site
1105110000657	ion pore; other site
1105110000658	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1105110000659	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1105110000660	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105110000661	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1105110000662	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1105110000663	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1105110000664	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1105110000665	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1105110000666	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1105110000667	beta subunit interaction interface [polypeptide binding]; other site
1105110000668	Walker A motif; other site
1105110000669	ATP binding site [chemical binding]; other site
1105110000670	Walker B motif; other site
1105110000671	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1105110000672	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1105110000673	core domain interface [polypeptide binding]; other site
1105110000674	delta subunit interface [polypeptide binding]; other site
1105110000675	epsilon subunit interface [polypeptide binding]; other site
1105110000676	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1105110000677	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1105110000678	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1105110000679	alpha subunit interaction interface [polypeptide binding]; other site
1105110000680	Walker A motif; other site
1105110000681	ATP binding site [chemical binding]; other site
1105110000682	Walker B motif; other site
1105110000683	inhibitor binding site; inhibition site
1105110000684	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1105110000685	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK01474
1105110000686	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1105110000687	gamma subunit interface [polypeptide binding]; other site
1105110000688	epsilon subunit interface [polypeptide binding]; other site
1105110000689	LBP interface [polypeptide binding]; other site
1105110000690	aconitate hydratase; Validated; Region: PRK09277
1105110000691	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1105110000692	substrate binding site [chemical binding]; other site
1105110000693	ligand binding site [chemical binding]; other site
1105110000694	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1105110000695	substrate binding site [chemical binding]; other site
1105110000696	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105110000697	Predicted membrane protein [Function unknown]; Region: COG3671
1105110000698	NADH dehydrogenase subunit G; Validated; Region: PRK09130
1105110000699	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1105110000700	catalytic loop [active]
1105110000701	iron binding site [ion binding]; other site
1105110000702	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1105110000703	MopB_Res_Cmplx1_Nad11: The second domain of the Nad11/75-kDa subunit of the NADH-quinone oxidoreductase/respiratory complex I/NADH dehydrogenase-1(NDH-1) of eukaryotes and the Nqo3/G subunit of alphaproteobacteria NDH-1. The NADH-quinone oxidoreductase...; Region: MopB_Res-Cmplx1_Nad11; cd02773
1105110000704	Domain of unknown function (DUF1982); Region: DUF1982; pfam09326
1105110000705	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1105110000706	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1105110000707	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1105110000708	4Fe-4S binding domain; Region: Fer4; cl02805
1105110000709	4Fe-4S binding domain; Region: Fer4; pfam00037
1105110000710	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13541
1105110000711	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110000712	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110000713	Walker A/P-loop; other site
1105110000714	Walker A/P-loop; other site
1105110000715	ATP binding site [chemical binding]; other site
1105110000716	ATP binding site [chemical binding]; other site
1105110000717	Q-loop/lid; other site
1105110000718	ABC transporter signature motif; other site
1105110000719	Walker B; other site
1105110000720	D-loop; other site
1105110000721	H-loop/switch region; other site
1105110000722	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1105110000723	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105110000724	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1105110000725	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1105110000726	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105110000727	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1105110000728	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1105110000729	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00213
1105110000730	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00213
1105110000731	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105110000732	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110000733	S-adenosylmethionine binding site [chemical binding]; other site
1105110000734	Predicted regulatory domain of a methyltransferase [General function prediction only]; Region: COG4797
1105110000735	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1105110000736	Integral membrane protein TerC family; Region: TerC; cl10468
1105110000737	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1105110000738	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1105110000739	seryl-tRNA synthetase; Provisional; Region: PRK05431
1105110000740	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1105110000741	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1105110000742	dimer interface [polypeptide binding]; other site
1105110000743	active site
1105110000744	motif 1; other site
1105110000745	motif 2; other site
1105110000746	motif 3; other site
1105110000747	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1105110000748	muropeptide transporter; Validated; Region: ampG; cl17669
1105110000749	Protein of unknown function; Region: DUF3971; pfam13116
1105110000750	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1105110000751	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1105110000752	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1105110000753	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1105110000754	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1105110000755	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1105110000756	putative active site [active]
1105110000757	putative PHP Thumb interface [polypeptide binding]; other site
1105110000758	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1105110000759	generic binding surface I; other site
1105110000760	generic binding surface II; other site
1105110000761	Uncharacterized metal-binding protein [General function prediction only]; Region: COG3894
1105110000762	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1105110000763	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1105110000764	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1105110000765	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1105110000766	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: HicB; COG4226
1105110000767	HicB family; Region: HicB; pfam05534
1105110000768	DNA polymerase I; Provisional; Region: PRK05755
1105110000769	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1105110000770	active site
1105110000771	metal binding site 1 [ion binding]; metal-binding site
1105110000772	putative 5' ssDNA interaction site; other site
1105110000773	metal binding site 3; metal-binding site
1105110000774	metal binding site 2 [ion binding]; metal-binding site
1105110000775	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1105110000776	putative DNA binding site [nucleotide binding]; other site
1105110000777	putative metal binding site [ion binding]; other site
1105110000778	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1105110000779	active site
1105110000780	substrate binding site [chemical binding]; other site
1105110000781	catalytic site [active]
1105110000782	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1105110000783	active site
1105110000784	DNA binding site [nucleotide binding]
1105110000785	catalytic site [active]
1105110000786	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1105110000787	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1105110000788	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1105110000789	P loop; other site
1105110000790	GTP binding site [chemical binding]; other site
1105110000791	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
1105110000792	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1105110000793	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
1105110000794	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1105110000795	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1105110000796	dimer interface [polypeptide binding]; other site
1105110000797	active site
1105110000798	CoA binding pocket [chemical binding]; other site
1105110000799	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1105110000800	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1105110000801	ligand binding site [chemical binding]; other site
1105110000802	Predicted permeases [General function prediction only]; Region: COG0795
1105110000803	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1105110000804	rod shape-determining protein MreB; Provisional; Region: PRK13927
1105110000805	MreB and similar proteins; Region: MreB_like; cd10225
1105110000806	nucleotide binding site [chemical binding]; other site
1105110000807	Mg binding site [ion binding]; other site
1105110000808	putative protofilament interaction site [polypeptide binding]; other site
1105110000809	RodZ interaction site [polypeptide binding]; other site
1105110000810	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
1105110000811	rod shape-determining protein MreC; Region: MreC; pfam04085
1105110000812	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105110000813	sequence-specific DNA binding site [nucleotide binding]; other site
1105110000814	salt bridge; other site
1105110000815	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1105110000816	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1105110000817	catalytic site [active]
1105110000818	G-X2-G-X-G-K; other site
1105110000819	potential frameshift: common BLAST hit: gi|374319737|ref|YP_005066236.1| Putative AAA+ superfamily ATPase
1105110000820	potential frameshift: common BLAST hit: gi|374319737|ref|YP_005066236.1| Putative AAA+ superfamily ATPase
1105110000821	ABC transporter ATPase component; Reviewed; Region: PRK11147
1105110000822	potential frameshift: common BLAST hit: gi|67459617|ref|YP_247241.1| ABC transporter ATP-binding protein
1105110000823	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1105110000824	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1105110000825	dimer interface [polypeptide binding]; other site
1105110000826	active site
1105110000827	acyl carrier protein; Provisional; Region: acpP; PRK00982
1105110000828	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1105110000829	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1105110000830	NAD(P) binding site [chemical binding]; other site
1105110000831	active site
1105110000832	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1105110000833	RecA/RadA recombinase [DNA replication, recombination, and repair]; Region: RecA; COG0468
1105110000834	hexamer interface [polypeptide binding]; other site
1105110000835	Walker A motif; other site
1105110000836	ATP binding site [chemical binding]; other site
1105110000837	Walker B motif; other site
1105110000838	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
1105110000839	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1105110000840	mce related protein; Region: MCE; pfam02470
1105110000841	hypothetical protein; Provisional; Region: PRK06630
1105110000842	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1105110000843	RNA/DNA hybrid binding site [nucleotide binding]; other site
1105110000844	active site
1105110000845	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3814
1105110000846	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3494
1105110000847	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1105110000848	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1105110000849	CoA-binding site [chemical binding]; other site
1105110000850	ATP-binding [chemical binding]; other site
1105110000851	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1105110000852	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1105110000853	active site
1105110000854	catalytic site [active]
1105110000855	substrate binding site [chemical binding]; other site
1105110000856	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
1105110000857	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1105110000858	Part of AAA domain; Region: AAA_19; pfam13245
1105110000859	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1105110000860	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
1105110000861	Family description; Region: UvrD_C_2; pfam13538
1105110000862	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1105110000863	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1105110000864	Domain of unknown function (DUF4415); Region: DUF4415; cl01401
1105110000865	Protein of unknown function (DUF497); Region: DUF497; cl01108
1105110000866	acetyl-CoA acetyltransferase; Provisional; Region: PRK06633
1105110000867	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1105110000868	dimer interface [polypeptide binding]; other site
1105110000869	active site
1105110000870	Poly(3-hydroxyalkanoate) synthetase [Lipid metabolism]; Region: PhaC; COG3243
1105110000871	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105110000872	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105110000873	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110000874	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1105110000875	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1105110000876	Transporter associated domain; Region: CorC_HlyC; smart01091
1105110000877	metal-binding heat shock protein; Provisional; Region: PRK00016
1105110000878	PemK-like protein; Region: PemK; pfam02452
1105110000879	Uncharacterized ACR, COG1753; Region: DUF217; cl00762
1105110000880	lipoyl synthase; Provisional; Region: PRK05481
1105110000881	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105110000882	FeS/SAM binding site; other site
1105110000883	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1105110000884	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1105110000885	dimer interface [polypeptide binding]; other site
1105110000886	active site
1105110000887	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1105110000888	folate binding site [chemical binding]; other site
1105110000889	potential frameshift: common BLAST hit: gi|78189365|ref|YP_379703.1| DNA modification methylase-like protein
1105110000890	putative hydrolase; Provisional; Region: PRK11460
1105110000891	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
1105110000892	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1105110000893	putative GSH binding site [chemical binding]; other site
1105110000894	catalytic residues [active]
1105110000895	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1105110000896	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1105110000897	minor groove reading motif; other site
1105110000898	helix-hairpin-helix signature motif; other site
1105110000899	substrate binding pocket [chemical binding]; other site
1105110000900	active site
1105110000901	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1105110000902	Predicted small secreted protein [Function unknown]; Region: COG5510
1105110000903	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105110000904	Predicted methyltransferases [General function prediction only]; Region: COG0313
1105110000905	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1105110000906	putative SAM binding site [chemical binding]; other site
1105110000907	putative homodimer interface [polypeptide binding]; other site
1105110000908	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1105110000909	putative ligand binding site [chemical binding]; other site
1105110000910	twin arginine translocase protein A; Provisional; Region: tatA; PRK01470
1105110000911	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1105110000912	tetramer interfaces [polypeptide binding]; other site
1105110000913	binuclear metal-binding site [ion binding]; other site
1105110000914	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1105110000915	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1105110000916	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1105110000917	aspartate kinase; Reviewed; Region: PRK06635
1105110000918	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1105110000919	putative nucleotide binding site [chemical binding]; other site
1105110000920	putative catalytic residues [active]
1105110000921	putative Mg ion binding site [ion binding]; other site
1105110000922	putative aspartate binding site [chemical binding]; other site
1105110000923	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1105110000924	putative allosteric regulatory residue; other site
1105110000925	Helix-turn-helix XRE-family like proteins; Region: HTH_XRE; smart00530
1105110000926	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1105110000927	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1105110000928	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
1105110000929	putative active site [active]
1105110000930	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110000931	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110000932	putative substrate translocation pore; other site
1105110000933	Cell division protein ZapA (stimulator of FtsZ polymerization and Z-ring component) [Cell cycle control, cell division,    chromosome partitioning]; Region: zapA; COG3027
1105110000934	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
1105110000935	Helix-turn-helix domain; Region: HTH_25; pfam13413
1105110000936	NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism]; Region: COG2902
1105110000937	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; smart00839
1105110000938	Predicted GTPase [General function prediction only]; Region: ThdF; COG0486
1105110000939	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1105110000940	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1105110000941	G1 box; other site
1105110000942	GTP/Mg2+ binding site [chemical binding]; other site
1105110000943	Switch I region; other site
1105110000944	G2 box; other site
1105110000945	Switch II region; other site
1105110000946	G3 box; other site
1105110000947	G4 box; other site
1105110000948	G5 box; other site
1105110000949	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1105110000950	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1105110000951	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1105110000952	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
1105110000953	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1105110000954	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1105110000955	nucleotide binding pocket [chemical binding]; other site
1105110000956	K-X-D-G motif; other site
1105110000957	catalytic site [active]
1105110000958	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1105110000959	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1105110000960	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1105110000961	Dimer interface [polypeptide binding]; other site
1105110000962	BRCT sequence motif; other site
1105110000963	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1105110000964	Protein of unknown function (DUF519); Region: DUF519; pfam04378
1105110000965	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1105110000966	Peptidase family M23; Region: Peptidase_M23; pfam01551
1105110000967	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1105110000968	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1105110000969	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1105110000970	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1105110000971	putative acyl-acceptor binding pocket; other site
1105110000972	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1105110000973	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1105110000974	catalytic triad [active]
1105110000975	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1105110000976	IHF dimer interface [polypeptide binding]; other site
1105110000977	IHF - DNA interface [nucleotide binding]; other site
1105110000978	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1105110000979	DNA binding residues [nucleotide binding]
1105110000980	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1105110000981	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1105110000982	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110000983	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105110000984	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105110000985	synthetase active site [active]
1105110000986	NTP binding site [chemical binding]; other site
1105110000987	metal binding site [ion binding]; metal-binding site
1105110000988	Rickettsia outer membrane protein B; Region: rOmpB; pfam12334
1105110000989	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1105110000990	Autotransporter beta-domain; Region: Autotransporter; smart00869
1105110000991	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110000992	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
1105110000993	Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536
1105110000994	Domain of unknown function DUF21; Region: DUF21; pfam01595
1105110000995	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1105110000996	Transporter associated domain; Region: CorC_HlyC; smart01091
1105110000997	Ulp1 protease family, C-terminal catalytic domain; Region: Peptidase_C48; cl17784
1105110000998	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1105110000999	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1105110001000	Walker A/P-loop; other site
1105110001001	ATP binding site [chemical binding]; other site
1105110001002	Q-loop/lid; other site
1105110001003	ABC transporter signature motif; other site
1105110001004	Walker B; other site
1105110001005	D-loop; other site
1105110001006	H-loop/switch region; other site
1105110001007	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
1105110001008	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1105110001009	FtsX-like permease family; Region: FtsX; pfam02687
1105110001010	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110001011	putative substrate translocation pore; other site
1105110001012	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1105110001013	Protein of unknown function (DUF2673); Region: DUF2673; pfam10880
1105110001014	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
1105110001015	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105110001016	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110001017	Walker A/P-loop; other site
1105110001018	ATP binding site [chemical binding]; other site
1105110001019	Q-loop/lid; other site
1105110001020	ABC transporter signature motif; other site
1105110001021	Walker B; other site
1105110001022	D-loop; other site
1105110001023	H-loop/switch region; other site
1105110001024	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1105110001025	Ligand Binding Site [chemical binding]; other site
1105110001026	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1105110001027	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1105110001028	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1105110001029	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1105110001030	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110001031	Walker A motif; other site
1105110001032	ATP binding site [chemical binding]; other site
1105110001033	Walker B motif; other site
1105110001034	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1105110001035	Predicted integral membrane protein (DUF2269); Region: DUF2269; pfam10027
1105110001036	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1105110001037	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; Region: NDUFA9_like_SDR_a; cd05271
1105110001038	putative NAD(P) binding site [chemical binding]; other site
1105110001039	active site
1105110001040	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1105110001041	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1105110001042	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
1105110001043	RmuC family; Region: RmuC; pfam02646
1105110001044	potential frameshift: common BLAST hit: gi|67458618|ref|YP_246242.1| ATPase
1105110001045	potential frameshift: common BLAST hit: gi|157804076|ref|YP_001492625.1| ATPase
1105110001046	LPS biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3475
1105110001047	valyl-tRNA synthetase; Reviewed; Region: valS; PRK13208
1105110001048	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105110001049	active site
1105110001050	HIGH motif; other site
1105110001051	nucleotide binding site [chemical binding]; other site
1105110001052	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1105110001053	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105110001054	active site
1105110001055	KMSKS motif; other site
1105110001056	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1105110001057	tRNA binding surface [nucleotide binding]; other site
1105110001058	anticodon binding site; other site
1105110001059	potential frameshift: common BLAST hit: gi|190571730|ref|YP_001976088.1| phage protein
1105110001060	4-hydroxybenzoate polyprenyltransferase; Reviewed; Region: ubiA; PRK12847
1105110001061	UbiA prenyltransferase family; Region: UbiA; pfam01040
1105110001062	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110001063	thymidylate kinase; Validated; Region: tmk; PRK00698
1105110001064	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1105110001065	TMP-binding site; other site
1105110001066	ATP-binding site [chemical binding]; other site
1105110001067	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
1105110001068	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1105110001069	HIGH motif; other site
1105110001070	active site
1105110001071	KMSKS motif; other site
1105110001072	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1105110001073	tRNA binding surface [nucleotide binding]; other site
1105110001074	anticodon binding site; other site
1105110001075	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1105110001076	active site
1105110001077	Poly-beta-hydroxyalkanoate depolymerase [Lipid metabolism]; Region: DepA; COG4553
1105110001078	PHB de-polymerase C-terminus; Region: PHB_depo_C; pfam06850
1105110001079	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105110001080	potential frameshift: common BLAST hit: gi|67458633|ref|YP_246257.1| mannose-1-phosphate guanylyltransferase
1105110001081	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1105110001082	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1105110001083	DNA binding site [nucleotide binding]
1105110001084	catalytic residue [active]
1105110001085	H2TH interface [polypeptide binding]; other site
1105110001086	putative catalytic residues [active]
1105110001087	turnover-facilitating residue; other site
1105110001088	intercalation triad [nucleotide binding]; other site
1105110001089	8OG recognition residue [nucleotide binding]; other site
1105110001090	putative reading head residues; other site
1105110001091	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1105110001092	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1105110001093	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1105110001094	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110001095	S-adenosylmethionine binding site [chemical binding]; other site
1105110001096	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1105110001097	ABC1 family; Region: ABC1; pfam03109
1105110001098	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1105110001099	active site
1105110001100	ATP binding site [chemical binding]; other site
1105110001101	GTP-binding protein Der; Reviewed; Region: PRK00093
1105110001102	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1105110001103	G1 box; other site
1105110001104	GTP/Mg2+ binding site [chemical binding]; other site
1105110001105	Switch I region; other site
1105110001106	G2 box; other site
1105110001107	Switch II region; other site
1105110001108	G3 box; other site
1105110001109	G4 box; other site
1105110001110	G5 box; other site
1105110001111	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1105110001112	G1 box; other site
1105110001113	GTP/Mg2+ binding site [chemical binding]; other site
1105110001114	Switch I region; other site
1105110001115	G2 box; other site
1105110001116	G3 box; other site
1105110001117	Switch II region; other site
1105110001118	G4 box; other site
1105110001119	G5 box; other site
1105110001120	Uncharacterized conserved protein [Function unknown]; Region: COG4095
1105110001121	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1105110001122	putative catalytic site [active]
1105110001123	putative phosphate binding site [ion binding]; other site
1105110001124	active site
1105110001125	metal binding site A [ion binding]; metal-binding site
1105110001126	DNA binding site [nucleotide binding]
1105110001127	putative AP binding site [nucleotide binding]; other site
1105110001128	putative metal binding site B [ion binding]; other site
1105110001129	Exonuclease VII, large subunit [DNA replication, recombination, and repair]; Region: XseA; COG1570
1105110001130	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1105110001131	generic binding surface II; other site
1105110001132	generic binding surface I; other site
1105110001133	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1105110001134	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1105110001135	SurA N-terminal domain; Region: SurA_N_3; cl07813
1105110001136	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1105110001137	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1105110001138	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110001139	S-adenosylmethionine binding site [chemical binding]; other site
1105110001140	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1105110001141	DNA-binding site [nucleotide binding]; DNA binding site
1105110001142	RNA-binding motif; other site
1105110001143	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1105110001144	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1105110001145	ATP binding site [chemical binding]; other site
1105110001146	Mg++ binding site [ion binding]; other site
1105110001147	motif III; other site
1105110001148	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105110001149	nucleotide binding region [chemical binding]; other site
1105110001150	ATP-binding site [chemical binding]; other site
1105110001151	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1105110001152	muropeptide transporter; Validated; Region: ampG; cl17669
1105110001153	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; smart00932
1105110001154	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1105110001155	Serine protease inhibitor ecotin [General function prediction only]; Region: Eco; COG4574
1105110001156	secondary substrate binding site; other site
1105110001157	primary substrate binding site; other site
1105110001158	inhibition loop; other site
1105110001159	dimerization interface [polypeptide binding]; other site
1105110001160	cell division protein FtsZ; Validated; Region: PRK09330
1105110001161	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1105110001162	nucleotide binding site [chemical binding]; other site
1105110001163	SulA interaction site; other site
1105110001164	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
1105110001165	putative active site [active]
1105110001166	metal binding site [ion binding]; metal-binding site
1105110001167	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1105110001168	Class II fumarases; Region: Fumarase_classII; cd01362
1105110001169	active site
1105110001170	tetramer interface [polypeptide binding]; other site
1105110001171	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1105110001172	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1105110001173	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1105110001174	elongation factor Tu; Reviewed; Region: PRK00049
1105110001175	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1105110001176	G1 box; other site
1105110001177	GEF interaction site [polypeptide binding]; other site
1105110001178	GTP/Mg2+ binding site [chemical binding]; other site
1105110001179	Switch I region; other site
1105110001180	G2 box; other site
1105110001181	G3 box; other site
1105110001182	Switch II region; other site
1105110001183	G4 box; other site
1105110001184	G5 box; other site
1105110001185	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1105110001186	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1105110001187	Antibiotic Binding Site [chemical binding]; other site
1105110001188	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1105110001189	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1105110001190	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1105110001191	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1105110001192	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1105110001193	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1105110001194	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1105110001195	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1105110001196	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1105110001197	putative translocon binding site; other site
1105110001198	protein-rRNA interface [nucleotide binding]; other site
1105110001199	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1105110001200	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1105110001201	G-X-X-G motif; other site
1105110001202	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1105110001203	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1105110001204	23S rRNA interface [nucleotide binding]; other site
1105110001205	5S rRNA interface [nucleotide binding]; other site
1105110001206	putative antibiotic binding site [chemical binding]; other site
1105110001207	L25 interface [polypeptide binding]; other site
1105110001208	L27 interface [polypeptide binding]; other site
1105110001209	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1105110001210	L23 interface [polypeptide binding]; other site
1105110001211	trigger factor interaction site; other site
1105110001212	23S rRNA interface [nucleotide binding]; other site
1105110001213	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1105110001214	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1105110001215	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1105110001216	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1105110001217	RNA binding site [nucleotide binding]; other site
1105110001218	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1105110001219	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1105110001220	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1105110001221	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1105110001222	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1105110001223	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1105110001224	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1105110001225	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1105110001226	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1105110001227	5S rRNA interface [nucleotide binding]; other site
1105110001228	23S rRNA interface [nucleotide binding]; other site
1105110001229	L5 interface [polypeptide binding]; other site
1105110001230	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1105110001231	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1105110001232	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1105110001233	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1105110001234	23S rRNA binding site [nucleotide binding]; other site
1105110001235	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1105110001236	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1105110001237	SecY translocase; Region: SecY; pfam00344
1105110001238	adenylate kinase; Reviewed; Region: adk; PRK00279
1105110001239	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1105110001240	AMP-binding site [chemical binding]; other site
1105110001241	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1105110001242	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
1105110001243	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1105110001244	30S ribosomal protein S11; Validated; Region: PRK05309
1105110001245	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1105110001246	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1105110001247	alphaNTD - beta interaction site [polypeptide binding]; other site
1105110001248	alphaNTD homodimer interface [polypeptide binding]; other site
1105110001249	alphaNTD - beta' interaction site [polypeptide binding]; other site
1105110001250	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1105110001251	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
1105110001252	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1105110001253	HD domain; Region: HD_4; pfam13328
1105110001254	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105110001255	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110001256	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110001257	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1105110001258	hypothetical protein; Validated; Region: PRK06620
1105110001259	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1105110001260	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1105110001261	GrpE; Region: GrpE; pfam01025
1105110001262	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1105110001263	dimer interface [polypeptide binding]; other site
1105110001264	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1105110001265	ribonuclease PH; Reviewed; Region: rph; PRK00173
1105110001266	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1105110001267	hexamer interface [polypeptide binding]; other site
1105110001268	active site
1105110001269	potential frameshift: common BLAST hit: gi|67458799|ref|YP_246423.1| glycosyltransferase
1105110001270	potential frameshift: common BLAST hit: gi|67458799|ref|YP_246423.1| glycosyltransferase
1105110001271	potential frameshift: common BLAST hit: gi|67458799|ref|YP_246423.1| glycosyltransferase
1105110001272	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1105110001273	oligomerisation interface [polypeptide binding]; other site
1105110001274	mobile loop; other site
1105110001275	roof hairpin; other site
1105110001276	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1105110001277	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1105110001278	ring oligomerisation interface [polypeptide binding]; other site
1105110001279	ATP/Mg binding site [chemical binding]; other site
1105110001280	stacking interactions; other site
1105110001281	hinge regions; other site
1105110001282	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105110001283	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105110001284	synthetase active site [active]
1105110001285	NTP binding site [chemical binding]; other site
1105110001286	metal binding site [ion binding]; metal-binding site
1105110001287	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105110001288	HD domain; Region: HD_4; pfam13328
1105110001289	Chitin binding domain; Region: Chitin_bind_3; pfam03067
1105110001290	Invasion associated locus B (IalB) protein; Region: IalB; cl02207
1105110001291	glutamyl-tRNA synthetase; Provisional; Region: gltX; PRK14895
1105110001292	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105110001293	HIGH motif; other site
1105110001294	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105110001295	active site
1105110001296	KMSKS motif; other site
1105110001297	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1105110001298	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110001299	S-adenosylmethionine binding site [chemical binding]; other site
1105110001300	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1105110001301	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1105110001302	ABC-ATPase subunit  interface; other site
1105110001303	dimer interface [polypeptide binding]; other site
1105110001304	putative PBP binding regions; other site
1105110001305	TfoX N-terminal domain; Region: TfoX_N; pfam04993
1105110001306	acylglycerophosphoethanolamine acyltransferase; Provisional; Region: PRK06814
1105110001307	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110001308	putative substrate translocation pore; other site
1105110001309	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1105110001310	putative acyl-acceptor binding pocket; other site
1105110001311	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1105110001312	acyl-activating enzyme (AAE) consensus motif; other site
1105110001313	putative AMP binding site [chemical binding]; other site
1105110001314	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1105110001315	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1105110001316	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1105110001317	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
1105110001318	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1105110001319	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1105110001320	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1105110001321	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1105110001322	carboxyltransferase (CT) interaction site; other site
1105110001323	biotinylation site [posttranslational modification]; other site
1105110001324	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105110001325	TPR repeat; Region: TPR_11; pfam13414
1105110001326	TPR motif; other site
1105110001327	binding surface
1105110001328	TPR repeat; Region: TPR_11; pfam13414
1105110001329	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105110001330	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105110001331	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
1105110001332	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1105110001333	HIGH motif; other site
1105110001334	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1105110001335	active site
1105110001336	KMSKS motif; other site
1105110001337	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1105110001338	tRNA binding surface [nucleotide binding]; other site
1105110001339	anticodon binding site; other site
1105110001340	Uncharacterized conserved protein [Function unknown]; Region: COG5590
1105110001341	COQ9; Region: COQ9; pfam08511
1105110001342	Ribosomal protein S21 [Translation, ribosomal structure and biogenesis]; Region: RpsU; COG0828
1105110001343	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]; Region: NtrY; COG5000
1105110001344	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1105110001345	dimerization interface [polypeptide binding]; other site
1105110001346	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105110001347	dimer interface [polypeptide binding]; other site
1105110001348	phosphorylation site [posttranslational modification]
1105110001349	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105110001350	ATP binding site [chemical binding]; other site
1105110001351	Mg2+ binding site [ion binding]; other site
1105110001352	G-X-G motif; other site
1105110001353	Phosphotransferase enzyme family; Region: APH; pfam01636
1105110001354	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1105110001355	active site
1105110001356	ATP binding site [chemical binding]; other site
1105110001357	potential frameshift: common BLAST hit: gi|67458820|ref|YP_246444.1| acetyltransferase
1105110001358	potential frameshift: common BLAST hit: gi|67458820|ref|YP_246444.1| acetyltransferase
1105110001359	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1105110001360	uncharacterized subgroup of the Escherichia coli Mg2+ transporter CorA_like subfamily; Region: EcCorA-like_u1; cd12837
1105110001361	Cl binding site [ion binding]; other site
1105110001362	oligomer interface [polypeptide binding]; other site
1105110001363	ribonuclease P; Reviewed; Region: rnpA; PRK01492
1105110001364	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1105110001365	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1105110001366	23S rRNA binding site [nucleotide binding]; other site
1105110001367	L21 binding site [polypeptide binding]; other site
1105110001368	L13 binding site [polypeptide binding]; other site
1105110001369	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1105110001370	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1105110001371	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105110001372	FeS/SAM binding site; other site
1105110001373	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1105110001374	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1105110001375	5S rRNA interface [nucleotide binding]; other site
1105110001376	CTC domain interface [polypeptide binding]; other site
1105110001377	L16 interface [polypeptide binding]; other site
1105110001378	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1105110001379	putative active site [active]
1105110001380	catalytic residue [active]
1105110001381	potential frameshift: common BLAST hit: gi|157826867|ref|YP_001495931.1| acetyltransferase
1105110001382	GTP-binding protein YchF; Reviewed; Region: PRK09601
1105110001383	YchF GTPase; Region: YchF; cd01900
1105110001384	G1 box; other site
1105110001385	GTP/Mg2+ binding site [chemical binding]; other site
1105110001386	Switch I region; other site
1105110001387	G2 box; other site
1105110001388	Switch II region; other site
1105110001389	G3 box; other site
1105110001390	G4 box; other site
1105110001391	G5 box; other site
1105110001392	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1105110001393	potential frameshift: common BLAST hit: gi|67459554|ref|YP_247178.1| nucleotidyltransferase/HEPN domain-containing protein
1105110001394	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1105110001395	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110001396	putative substrate translocation pore; other site
1105110001397	Patatin [General function prediction only]; Region: COG3621
1105110001398	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1105110001399	active site
1105110001400	nucleophile elbow; other site
1105110001401	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1105110001402	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105110001403	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110001404	Walker A motif; other site
1105110001405	ATP binding site [chemical binding]; other site
1105110001406	Walker B motif; other site
1105110001407	arginine finger; other site
1105110001408	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1105110001409	DnaA box-binding interface [nucleotide binding]; other site
1105110001410	Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins; Region: RHOD_1; cd01522
1105110001411	active site residue [active]
1105110001412	Uncharacterized conserved protein [Function unknown]; Region: COG2938
1105110001413	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1105110001414	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1105110001415	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105110001416	ATP binding site [chemical binding]; other site
1105110001417	putative Mg++ binding site [ion binding]; other site
1105110001418	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105110001419	nucleotide binding region [chemical binding]; other site
1105110001420	ATP-binding site [chemical binding]; other site
1105110001421	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1105110001422	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1105110001423	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1105110001424	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105110001425	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105110001426	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1105110001427	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
1105110001428	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105110001429	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105110001430	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1105110001431	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1105110001432	Mg++ binding site [ion binding]; other site
1105110001433	putative catalytic motif [active]
1105110001434	putative substrate binding site [chemical binding]; other site
1105110001435	V-type ATP synthase subunit I; Validated; Region: PRK05771
1105110001436	potential frameshift: common BLAST hit: gi|67458764|ref|YP_246388.1| tryptophan repressor binding protein
1105110001437	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1105110001438	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1105110001439	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110001440	RecG-like helicase [DNA replication, recombination, and repair / Transcription]; Region: RecG; COG1200
1105110001441	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1105110001442	ssDNA binding site; other site
1105110001443	generic binding surface II; other site
1105110001444	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105110001445	ATP binding site [chemical binding]; other site
1105110001446	putative Mg++ binding site [ion binding]; other site
1105110001447	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105110001448	nucleotide binding region [chemical binding]; other site
1105110001449	ATP-binding site [chemical binding]; other site
1105110001450	TraX protein; Region: TraX; pfam05857
1105110001451	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1105110001452	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1105110001453	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1105110001454	dimer interface [polypeptide binding]; other site
1105110001455	substrate binding site [chemical binding]; other site
1105110001456	metal binding sites [ion binding]; metal-binding site
1105110001457	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13254
1105110001458	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1105110001459	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1105110001460	Cu(I) binding site [ion binding]; other site
1105110001461	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1105110001462	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1105110001463	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1105110001464	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1105110001465	potential frameshift: common BLAST hit: gi|67459345|ref|YP_246969.1| guanosine polyphosphate pyrophosphohydrolase/synthetase-like
1105110001466	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1105110001467	MgtE intracellular N domain; Region: MgtE_N; pfam03448
1105110001468	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1105110001469	Divalent cation transporter; Region: MgtE; pfam01769
1105110001470	HAD-superfamily class IIA hydrolase, TIGR01459; Region: HAD-SF-IIA-hyp4
1105110001471	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1105110001472	active site
1105110001473	motif I; other site
1105110001474	motif II; other site
1105110001475	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1105110001476	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1105110001477	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105110001478	Mg2+ binding site [ion binding]; other site
1105110001479	G-X-G motif; other site
1105110001480	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1105110001481	anchoring element; other site
1105110001482	dimer interface [polypeptide binding]; other site
1105110001483	ATP binding site [chemical binding]; other site
1105110001484	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1105110001485	active site
1105110001486	putative metal-binding site [ion binding]; other site
1105110001487	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1105110001488	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1105110001489	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1105110001490	hinge; other site
1105110001491	active site
1105110001492	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1105110001493	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1105110001494	peptidylprolyl isomerase; Provisional; Region: prsA; PRK04405
1105110001495	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1105110001496	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1105110001497	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1105110001498	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1105110001499	SEC-C motif; Region: SEC-C; pfam02810
1105110001500	potential frameshift: common BLAST hit: gi|67459332|ref|YP_246956.1| nucleotidyltransferase/HEPN domain-containing protein
1105110001501	potential frameshift: common BLAST hit: gi|67459331|ref|YP_246955.1| ankyrin repeat-containing protein
1105110001502	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105110001503	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105110001504	potential frameshift: common BLAST hit: gi|91205221|ref|YP_537576.1| Type I restriction-modification system, M subunit
1105110001505	potential frameshift: common BLAST hit: gi|91205221|ref|YP_537576.1| Type I restriction-modification system, M subunit
1105110001506	potential frameshift: common BLAST hit: gi|91205221|ref|YP_537576.1| Type I restriction-modification system, M subunit
1105110001507	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1105110001508	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1105110001509	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1105110001510	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
1105110001511	potential frameshift: common BLAST hit: gi|91205217|ref|YP_537572.1| Type I site-specific restriction-modification system, R
1105110001512	potential frameshift: common BLAST hit: gi|67459310|ref|YP_246934.1| Type I site-specific restriction-modification system, R
1105110001513	potential frameshift: common BLAST hit: gi|67459310|ref|YP_246934.1| Type I site-specific restriction-modification system, R
1105110001514	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1105110001515	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1105110001516	DNA binding site [nucleotide binding]
1105110001517	active site
1105110001518	A new structural DNA glycosylase; Region: AlkD_like; cl11434
1105110001519	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
1105110001520	A new structural DNA glycosylase; Region: AlkD_like; cd06561
1105110001521	active site
1105110001522	Copper(I)-binding protein [Inorganic ion transport and    metabolism]; Region: COG2847
1105110001523	potential frameshift: common BLAST hit: gi|157825946|ref|YP_001493666.1| excinuclease ABC subunit C
1105110001524	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
1105110001525	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1105110001526	Na binding site [ion binding]; other site
1105110001527	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2001
1105110001528	MraZ protein; Region: MraZ; pfam02381
1105110001529	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1105110001530	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110001531	S-adenosylmethionine binding site [chemical binding]; other site
1105110001532	Predicted secreted (periplasmic) protein [Function unknown]; Region: COG5462
1105110001533	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1105110001534	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1105110001535	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1105110001536	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1105110001537	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1105110001538	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1105110001539	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105110001540	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1105110001541	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1105110001542	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1105110001543	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1105110001544	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105110001545	active site
1105110001546	phosphorylation site [posttranslational modification]
1105110001547	intermolecular recognition site; other site
1105110001548	dimerization interface [polypeptide binding]; other site
1105110001549	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110001550	Walker A motif; other site
1105110001551	ATP binding site [chemical binding]; other site
1105110001552	Walker B motif; other site
1105110001553	arginine finger; other site
1105110001554	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1105110001555	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12612
1105110001556	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1105110001557	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK06617
1105110001558	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110001559	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1105110001560	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1105110001561	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1105110001562	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1105110001563	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
1105110001564	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1105110001565	substrate binding site [chemical binding]; other site
1105110001566	oxyanion hole (OAH) forming residues; other site
1105110001567	trimer interface [polypeptide binding]; other site
1105110001568	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1105110001569	MG2 domain; Region: A2M_N; pfam01835
1105110001570	Alpha-2-macroglobulin family; Region: A2M; pfam00207
1105110001571	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1105110001572	surface patch; other site
1105110001573	thioester region; other site
1105110001574	specificity defining residues; other site
1105110001575	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1105110001576	active site
1105110001577	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110001578	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105110001579	HD domain; Region: HD_4; pfam13328
1105110001580	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110001581	PII uridylyl-transferase; Provisional; Region: PRK05007
1105110001582	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1105110001583	active site
1105110001584	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5304
1105110001585	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5304
1105110001586	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1105110001587	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1105110001588	active site
1105110001589	HIGH motif; other site
1105110001590	dimer interface [polypeptide binding]; other site
1105110001591	KMSKS motif; other site
1105110001592	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105110001593	RNA binding surface [nucleotide binding]; other site
1105110001594	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1105110001595	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105110001596	RNA binding surface [nucleotide binding]; other site
1105110001597	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1105110001598	Fic/DOC family; Region: Fic; pfam02661
1105110001599	Fic family protein [Function unknown]; Region: COG3177
1105110001600	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1105110001601	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1105110001602	DNA binding residues [nucleotide binding]
1105110001603	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG0779
1105110001604	Sm and related proteins; Region: Sm_like; cl00259
1105110001605	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1105110001606	putative oligomer interface [polypeptide binding]; other site
1105110001607	putative RNA binding site [nucleotide binding]; other site
1105110001608	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1105110001609	NusA N-terminal domain; Region: NusA_N; pfam08529
1105110001610	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1105110001611	RNA binding site [nucleotide binding]; other site
1105110001612	homodimer interface [polypeptide binding]; other site
1105110001613	NusA-like KH domain; Region: KH_5; pfam13184
1105110001614	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1105110001615	G-X-X-G motif; other site
1105110001616	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1105110001617	translation initiation factor IF-2; Validated; Region: infB; PRK05306
1105110001618	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1105110001619	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1105110001620	G1 box; other site
1105110001621	putative GEF interaction site [polypeptide binding]; other site
1105110001622	GTP/Mg2+ binding site [chemical binding]; other site
1105110001623	Switch I region; other site
1105110001624	G2 box; other site
1105110001625	G3 box; other site
1105110001626	Switch II region; other site
1105110001627	G4 box; other site
1105110001628	G5 box; other site
1105110001629	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1105110001630	Translation-initiation factor 2; Region: IF-2; pfam11987
1105110001631	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1105110001632	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1105110001633	Glycoprotease family; Region: Peptidase_M22; pfam00814
1105110001634	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1105110001635	Recombination protein O N terminal; Region: RecO_N; pfam11967
1105110001636	Recombination protein O C terminal; Region: RecO_C; pfam02565
1105110001637	DNA repair protein RadA; Provisional; Region: PRK11823
1105110001638	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1105110001639	Walker A motif/ATP binding site; other site
1105110001640	ATP binding site [chemical binding]; other site
1105110001641	Walker B motif; other site
1105110001642	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1105110001643	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1105110001644	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110001645	S-adenosylmethionine binding site [chemical binding]; other site
1105110001646	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1105110001647	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1105110001648	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1105110001649	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1105110001650	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1105110001651	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1105110001652	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105110001653	RNA binding surface [nucleotide binding]; other site
1105110001654	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1105110001655	active site
1105110001656	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1105110001657	replicative DNA helicase; Provisional; Region: PRK09165
1105110001658	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1105110001659	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1105110001660	Walker A motif; other site
1105110001661	ATP binding site [chemical binding]; other site
1105110001662	Walker B motif; other site
1105110001663	DNA binding loops [nucleotide binding]
1105110001664	polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases; Region: ubiX_pad; TIGR00421
1105110001665	Flavoprotein; Region: Flavoprotein; pfam02441
1105110001666	primosome assembly protein PriA; Validated; Region: PRK05580
1105110001667	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105110001668	ATP binding site [chemical binding]; other site
1105110001669	putative Mg++ binding site [ion binding]; other site
1105110001670	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1105110001671	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
1105110001672	dimer interface [polypeptide binding]; other site
1105110001673	allosteric magnesium binding site [ion binding]; other site
1105110001674	active site
1105110001675	aspartate-rich active site metal binding site; other site
1105110001676	Schiff base residues; other site
1105110001677	NADH dehydrogenase subunit 2; Provisional; Region: ND2; MTH00196
1105110001678	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105110001679	potential frameshift: common BLAST hit: gi|15892293|ref|NP_360007.1| ATP-dependent protease subunit C (ClpC)
1105110001680	potential frameshift: common BLAST hit: gi|157826519|ref|YP_001495583.1| NACHT family NTPase
1105110001681	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105110001682	iron-sulfur cluster assembly transcription factor IscR; Region: IscR; TIGR02010
1105110001683	Rrf2 family protein; Region: rrf2_super; TIGR00738
1105110001684	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1105110001685	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1105110001686	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1105110001687	catalytic residue [active]
1105110001688	cysteine desulfurase; Provisional; Region: PRK14012
1105110001689	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1105110001690	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1105110001691	catalytic residue [active]
1105110001692	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1105110001693	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1105110001694	trimerization site [polypeptide binding]; other site
1105110001695	active site
1105110001696	Iron-sulfur cluster assembly accessory protein; Region: TIGR00049
1105110001697	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
1105110001698	arginine:agmatin antiporter; Provisional; Region: PRK10644
1105110001699	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1105110001700	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1105110001701	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
1105110001702	active site
1105110001703	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1105110001704	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1105110001705	substrate binding pocket [chemical binding]; other site
1105110001706	chain length determination region; other site
1105110001707	substrate-Mg2+ binding site; other site
1105110001708	catalytic residues [active]
1105110001709	aspartate-rich region 1; other site
1105110001710	active site lid residues [active]
1105110001711	aspartate-rich region 2; other site
1105110001712	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105110001713	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105110001714	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1105110001715	AmpG-like permease; Region: 2A0125; TIGR00901
1105110001716	Lysine efflux permease [General function prediction only]; Region: COG1279
1105110001717	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1105110001718	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1105110001719	active site
1105110001720	HemY protein N-terminus; Region: HemY_N; pfam07219
1105110001721	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
1105110001722	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1105110001723	RelB antitoxin; Region: RelB; cl01171
1105110001724	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
1105110001725	Protein required for attachment to host cells; Region: Host_attach; cl02398
1105110001726	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1105110001727	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1105110001728	putative acyl-acceptor binding pocket; other site
1105110001729	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1105110001730	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1105110001731	active site
1105110001732	HIGH motif; other site
1105110001733	dimer interface [polypeptide binding]; other site
1105110001734	KMSKS motif; other site
1105110001735	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1105110001736	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1105110001737	domain interfaces; other site
1105110001738	active site
1105110001739	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1105110001740	dimer interface [polypeptide binding]; other site
1105110001741	catalytic triad [active]
1105110001742	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1105110001743	Na binding site [ion binding]; other site
1105110001744	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1105110001745	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105110001746	dimer interface [polypeptide binding]; other site
1105110001747	phosphorylation site [posttranslational modification]
1105110001748	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105110001749	ATP binding site [chemical binding]; other site
1105110001750	Mg2+ binding site [ion binding]; other site
1105110001751	G-X-G motif; other site
1105110001752	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
1105110001753	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1105110001754	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1105110001755	Uncharacterized conserved protein [Function unknown]; Region: COG1723
1105110001756	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
1105110001757	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1105110001758	catalytic site [active]
1105110001759	putative active site [active]
1105110001760	putative substrate binding site [chemical binding]; other site
1105110001761	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1105110001762	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
1105110001763	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1105110001764	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
1105110001765	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1105110001766	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105110001767	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1105110001768	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110001769	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1105110001770	S-adenosylmethionine binding site [chemical binding]; other site
1105110001771	Protein of unknown function (DUF2532); Region: DUF2532; pfam10811
1105110001772	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1105110001773	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1105110001774	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1105110001775	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1105110001776	hypothetical protein; Validated; Region: PRK00110
1105110001777	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1105110001778	Substrate binding site; other site
1105110001779	Mg++ binding site; other site
1105110001780	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
1105110001781	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
1105110001782	homotetramer interface [polypeptide binding]; other site
1105110001783	FMN binding site [chemical binding]; other site
1105110001784	homodimer contacts [polypeptide binding]; other site
1105110001785	putative active site [active]
1105110001786	putative substrate binding site [chemical binding]; other site
1105110001787	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1105110001788	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105110001789	potential frameshift: common BLAST hit: gi|67459166|ref|YP_246790.1| streptomycin 6-kinase
1105110001790	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1105110001791	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1105110001792	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1105110001793	oligomer interface [polypeptide binding]; other site
1105110001794	active site residues [active]
1105110001795	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1105110001796	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1105110001797	RNA binding site [nucleotide binding]; other site
1105110001798	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1105110001799	RNA binding site [nucleotide binding]; other site
1105110001800	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1105110001801	RNA binding site [nucleotide binding]; other site
1105110001802	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105110001803	RNA binding site [nucleotide binding]; other site
1105110001804	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105110001805	RNA binding site [nucleotide binding]; other site
1105110001806	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105110001807	RNA binding site [nucleotide binding]; other site
1105110001808	Cytidylate kinase [Nucleotide transport and metabolism]; Region: Cmk; COG0283
1105110001809	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1105110001810	CMP-binding site; other site
1105110001811	The sites determining sugar specificity; other site
1105110001812	Protein of unknown function (DUF328); Region: DUF328; pfam03883
1105110001813	Bacterial nucleoid DNA-binding protein [DNA replication, recombination, and repair]; Region: HimA; COG0776
1105110001814	IHF - DNA interface [nucleotide binding]; other site
1105110001815	IHF dimer interface [polypeptide binding]; other site
1105110001816	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1105110001817	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1105110001818	tandem repeat interface [polypeptide binding]; other site
1105110001819	oligomer interface [polypeptide binding]; other site
1105110001820	active site residues [active]
1105110001821	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1105110001822	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1105110001823	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1105110001824	RNA binding site [nucleotide binding]; other site
1105110001825	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1105110001826	multimer interface [polypeptide binding]; other site
1105110001827	Walker A motif; other site
1105110001828	ATP binding site [chemical binding]; other site
1105110001829	Walker B motif; other site
1105110001830	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110001831	S-adenosylmethionine binding site [chemical binding]; other site
1105110001832	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105110001833	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1105110001834	DHH family; Region: DHH; pfam01368
1105110001835	DHHA1 domain; Region: DHHA1; pfam02272
1105110001836	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1105110001837	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1105110001838	RF-1 domain; Region: RF-1; pfam00472
1105110001839	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1105110001840	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; Region: PDHac_trf_mito; TIGR01349
1105110001841	E3 interaction surface; other site
1105110001842	lipoyl attachment site [posttranslational modification]; other site
1105110001843	e3 binding domain; Region: E3_binding; pfam02817
1105110001844	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1105110001845	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1105110001846	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1105110001847	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1105110001848	Predicted membrane protein [Function unknown]; Region: COG5346
1105110001849	Phage conserved hypothetical protein BR0599; Region: Phage_BR0599; pfam09356
1105110001850	Uncharacterized conserved protein (DUF2163); Region: DUF2163; pfam09931
1105110001851	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
1105110001852	potential frameshift: common BLAST hit: gi|157827542|ref|YP_001496606.1| Phage prohead protease and phage major capsid protein
1105110001853	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1105110001854	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1105110001855	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1105110001856	potential frameshift: common BLAST hit: gi|157964571|ref|YP_001499395.1| putative esterase of the alpha/beta hydrolase superfamily protein
1105110001857	potential frameshift: common BLAST hit: gi|157964571|ref|YP_001499395.1| putative esterase of the alpha/beta hydrolase superfamily protein
1105110001858	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1105110001859	potential frameshift: common BLAST hit: gi|157964571|ref|YP_001499395.1| putative esterase of the alpha/beta hydrolase superfamily protein
1105110001860	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1105110001861	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1105110001862	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1105110001863	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1105110001864	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
1105110001865	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP); Region: GATase1_ScBLP_like; cd03144
1105110001866	conserved cys residue [active]
1105110001867	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1105110001868	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1105110001869	GSH binding site (G-site) [chemical binding]; other site
1105110001870	C-terminal domain interface [polypeptide binding]; other site
1105110001871	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cd00299
1105110001872	N-terminal domain interface [polypeptide binding]; other site
1105110001873	dimer interface [polypeptide binding]; other site
1105110001874	substrate binding pocket (H-site) [chemical binding]; other site
1105110001875	pyruvate phosphate dikinase; Provisional; Region: PRK09279
1105110001876	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1105110001877	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1105110001878	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1105110001879	hypothetical protein; Provisional; Region: PRK06661
1105110001880	intersubunit interface [polypeptide binding]; other site
1105110001881	active site
1105110001882	Zn2+ binding site [ion binding]; other site
1105110001883	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1105110001884	active site
1105110001885	catalytic residues [active]
1105110001886	metal binding site [ion binding]; metal-binding site
1105110001887	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1105110001888	uncharacterized protein, YfiH family; Region: TIGR00726
1105110001889	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1105110001890	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1105110001891	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
1105110001892	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1105110001893	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105110001894	non-specific DNA binding site [nucleotide binding]; other site
1105110001895	salt bridge; other site
1105110001896	sequence-specific DNA binding site [nucleotide binding]; other site
1105110001897	120 KDa Rickettsia surface antigen; Region: 120_Rick_ant; pfam12574
1105110001898	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105110001899	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01528
1105110001900	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1105110001901	RNA binding site [nucleotide binding]; other site
1105110001902	active site
1105110001903	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1105110001904	16S/18S rRNA binding site [nucleotide binding]; other site
1105110001905	S13e-L30e interaction site [polypeptide binding]; other site
1105110001906	25S rRNA binding site [nucleotide binding]; other site
1105110001907	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1105110001908	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1105110001909	RNase E interface [polypeptide binding]; other site
1105110001910	trimer interface [polypeptide binding]; other site
1105110001911	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1105110001912	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1105110001913	RNase E interface [polypeptide binding]; other site
1105110001914	trimer interface [polypeptide binding]; other site
1105110001915	active site
1105110001916	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1105110001917	putative nucleic acid binding region [nucleotide binding]; other site
1105110001918	G-X-X-G motif; other site
1105110001919	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1105110001920	RNA binding site [nucleotide binding]; other site
1105110001921	domain interface; other site
1105110001922	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1105110001923	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1105110001924	putative active site [active]
1105110001925	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1105110001926	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5375
1105110001927	OstA-like protein; Region: OstA; cl00844
1105110001928	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1105110001929	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1105110001930	Walker A/P-loop; other site
1105110001931	ATP binding site [chemical binding]; other site
1105110001932	Q-loop/lid; other site
1105110001933	ABC transporter signature motif; other site
1105110001934	Walker B; other site
1105110001935	D-loop; other site
1105110001936	H-loop/switch region; other site
1105110001937	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1105110001938	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1105110001939	active site
1105110001940	substrate binding site [chemical binding]; other site
1105110001941	metal binding site [ion binding]; metal-binding site
1105110001942	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1105110001943	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1105110001944	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1105110001945	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110001946	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1105110001947	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1105110001948	dimer interface [polypeptide binding]; other site
1105110001949	putative radical transfer pathway; other site
1105110001950	diiron center [ion binding]; other site
1105110001951	tyrosyl radical; other site
1105110001952	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
1105110001953	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1105110001954	active site
1105110001955	dimer interface [polypeptide binding]; other site
1105110001956	catalytic residues [active]
1105110001957	effector binding site; other site
1105110001958	R2 peptide binding site; other site
1105110001959	potential frameshift: common BLAST hit: gi|157827080|ref|YP_001496144.1| P pilus assembly, fimbrial usher protein
1105110001960	potential frameshift: common BLAST hit: gi|67459097|ref|YP_246721.1| P pilus assembly protein FimD
1105110001961	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1105110001962	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1105110001963	Spore Coat Protein U domain; Region: SCPU; cl02253
1105110001964	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
1105110001965	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1105110001966	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1105110001967	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1105110001968	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105110001969	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14171
1105110001970	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1105110001971	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1105110001972	homodimer interface [polypeptide binding]; other site
1105110001973	NADP binding site [chemical binding]; other site
1105110001974	substrate binding site [chemical binding]; other site
1105110001975	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1105110001976	30S subunit binding site; other site
1105110001977	Autotransporter beta-domain; Region: Autotransporter; smart00869
1105110001978	potential frameshift: common BLAST hit: gi|67459085|ref|YP_246709.1| cell surface antigen Sca3
1105110001979	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1105110001980	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1105110001981	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110001982	Walker A motif; other site
1105110001983	ATP binding site [chemical binding]; other site
1105110001984	Walker B motif; other site
1105110001985	arginine finger; other site
1105110001986	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1105110001987	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1105110001988	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1105110001989	tetramer interface [polypeptide binding]; other site
1105110001990	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105110001991	catalytic residue [active]
1105110001992	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1105110001993	Part of AAA domain; Region: AAA_19; pfam13245
1105110001994	Family description; Region: UvrD_C_2; pfam13538
1105110001995	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105110001996	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1105110001997	active site
1105110001998	potential frameshift: common BLAST hit: gi|157825748|ref|YP_001493468.1| succinate semialdehyde dehydrogenase
1105110001999	potential frameshift: common BLAST hit: gi|67459076|ref|YP_246700.1| succinate semialdehyde dehydrogenase
1105110002000	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110002001	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1105110002002	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1105110002003	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105110002004	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1105110002005	Predicted permeases [General function prediction only]; Region: COG0679
1105110002006	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1105110002007	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1105110002008	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1105110002009	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1105110002010	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1105110002011	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1105110002012	inorganic polyphosphate/ATP-NAD kinase; Reviewed; Region: ppnK; PRK04761
1105110002013	potential frameshift: common BLAST hit: gi|341583725|ref|YP_004764216.1| negative regulator of beta-lactamase expression
1105110002014	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
1105110002015	RecR protein; Region: RecR; pfam02132
1105110002016	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1105110002017	putative active site [active]
1105110002018	putative metal-binding site [ion binding]; other site
1105110002019	tetramer interface [polypeptide binding]; other site
1105110002020	Predicted membrane protein/domain [Function unknown]; Region: COG1714
1105110002021	Predicted membrane protein [Function unknown]; Region: COG1238
1105110002022	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1105110002023	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4395
1105110002024	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1105110002025	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1105110002026	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1105110002027	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1105110002028	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1105110002029	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1105110002030	CoA-ligase; Region: Ligase_CoA; pfam00549
1105110002031	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1105110002032	CoA binding domain; Region: CoA_binding; pfam02629
1105110002033	CoA-ligase; Region: Ligase_CoA; pfam00549
1105110002034	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1105110002035	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1105110002036	catalytic residues [active]
1105110002037	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1105110002038	SmpB-tmRNA interface; other site
1105110002039	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1105110002040	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1105110002041	dimer interface [polypeptide binding]; other site
1105110002042	active site
1105110002043	catalytic residue [active]
1105110002044	branched-chain amino acid aminotransferase; Validated; Region: PRK06606
1105110002045	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1105110002046	homodimer interface [polypeptide binding]; other site
1105110002047	substrate-cofactor binding pocket; other site
1105110002048	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105110002049	catalytic residue [active]
1105110002050	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1105110002051	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105110002052	active site
1105110002053	phosphorylation site [posttranslational modification]
1105110002054	intermolecular recognition site; other site
1105110002055	dimerization interface [polypeptide binding]; other site
1105110002056	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1105110002057	DNA binding site [nucleotide binding]
1105110002058	HAMP domain; Region: HAMP; pfam00672
1105110002059	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105110002060	dimer interface [polypeptide binding]; other site
1105110002061	phosphorylation site [posttranslational modification]
1105110002062	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105110002063	ATP binding site [chemical binding]; other site
1105110002064	Mg2+ binding site [ion binding]; other site
1105110002065	G-X-G motif; other site
1105110002066	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1105110002067	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1105110002068	catalytic residue [active]
1105110002069	putative FPP diphosphate  binding site; other site
1105110002070	putative FPP binding hydrophobic cleft; other site
1105110002071	dimer interface [polypeptide binding]; other site
1105110002072	putative IPP diphosphate binding site; other site
1105110002073	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1105110002074	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1105110002075	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1105110002076	Septum formation initiator; Region: DivIC; pfam04977
1105110002077	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
1105110002078	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1105110002079	catalytic site [active]
1105110002080	putative active site [active]
1105110002081	putative substrate binding site [chemical binding]; other site
1105110002082	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1105110002083	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1105110002084	HIGH motif; other site
1105110002085	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1105110002086	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105110002087	active site
1105110002088	KMSKS motif; other site
1105110002089	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1105110002090	tRNA binding surface [nucleotide binding]; other site
1105110002091	Domain of unknown function (DUF3576); Region: DUF3576; pfam12100
1105110002092	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1105110002093	DNA polymerase III subunit beta; Validated; Region: PRK05643
1105110002094	putative DNA binding surface [nucleotide binding]; other site
1105110002095	dimer interface [polypeptide binding]; other site
1105110002096	beta-clamp/clamp loader binding surface; other site
1105110002097	beta-clamp/translesion DNA polymerase binding surface; other site
1105110002098	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1105110002099	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1105110002100	putative tRNA-binding site [nucleotide binding]; other site
1105110002101	B3/4 domain; Region: B3_4; pfam03483
1105110002102	tRNA synthetase B5 domain; Region: B5; smart00874
1105110002103	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1105110002104	dimer interface [polypeptide binding]; other site
1105110002105	motif 1; other site
1105110002106	motif 3; other site
1105110002107	motif 2; other site
1105110002108	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1105110002109	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1105110002110	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1105110002111	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1105110002112	dimer interface [polypeptide binding]; other site
1105110002113	motif 1; other site
1105110002114	active site
1105110002115	motif 2; other site
1105110002116	motif 3; other site
1105110002117	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1105110002118	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1105110002119	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105110002120	FeS/SAM binding site; other site
1105110002121	diaminopimelate epimerase; Region: DapF; TIGR00652
1105110002122	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1105110002123	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1105110002124	potential frameshift: common BLAST hit: gi|350273485|ref|YP_004884798.1| transposase and inactivated derivative
1105110002125	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1105110002126	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1105110002127	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1105110002128	HlyD family secretion protein; Region: HlyD_3; pfam13437
1105110002129	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1105110002130	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1105110002131	potential frameshift: common BLAST hit: gi|91205462|ref|YP_537817.1| RND family efflux transporter
1105110002132	potential frameshift: common BLAST hit: gi|67459031|ref|YP_246655.1| RND family efflux transporter
1105110002133	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1105110002134	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1105110002135	active site
1105110002136	homodimer interface [polypeptide binding]; other site
1105110002137	cell division protein FtsW; Region: ftsW; TIGR02614
1105110002138	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01368
1105110002139	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105110002140	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105110002141	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105110002142	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1105110002143	Protein of unknown function (DUF3035); Region: DUF3035; pfam11233
1105110002144	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1105110002145	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1105110002146	Peptidase family M23; Region: Peptidase_M23; pfam01551
1105110002147	Cytidylyltransferase [Cell envelope biogenesis, outer membrane / Lipid metabolism]; Region: TagD; COG0615
1105110002148	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1105110002149	active site
1105110002150	HIGH motif; other site
1105110002151	nucleotide binding site [chemical binding]; other site
1105110002152	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105110002153	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
1105110002154	cytochrome c oxidase subunit II; Provisional; Region: COX2; MTH00154
1105110002155	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1105110002156	cytochrome c oxidase subunit I; Validated; Region: COX1; MTH00007
1105110002157	Cytochrome C oxidase subunit I.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663
1105110002158	Subunit I/III interface [polypeptide binding]; other site
1105110002159	D-pathway; other site
1105110002160	Subunit I/VIIc interface [polypeptide binding]; other site
1105110002161	Subunit I/IV interface [polypeptide binding]; other site
1105110002162	Subunit I/II interface [polypeptide binding]; other site
1105110002163	Low-spin heme (heme a) binding site [chemical binding]; other site
1105110002164	Subunit I/VIIa interface [polypeptide binding]; other site
1105110002165	Subunit I/VIa interface [polypeptide binding]; other site
1105110002166	Dimer interface; other site
1105110002167	Putative water exit pathway; other site
1105110002168	Binuclear center (heme a3/CuB) [ion binding]; other site
1105110002169	K-pathway; other site
1105110002170	Subunit I/Vb interface [polypeptide binding]; other site
1105110002171	Putative proton exit pathway; other site
1105110002172	Subunit I/VIb interface; other site
1105110002173	Subunit I/VIc interface [polypeptide binding]; other site
1105110002174	Electron transfer pathway; other site
1105110002175	Subunit I/VIIIb interface [polypeptide binding]; other site
1105110002176	Subunit I/VIIb interface [polypeptide binding]; other site
1105110002177	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1105110002178	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1105110002179	catalytic triad [active]
1105110002180	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105110002181	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
1105110002182	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1105110002183	dimer interface [polypeptide binding]; other site
1105110002184	catalytic triad [active]
1105110002185	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1105110002186	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1105110002187	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1105110002188	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1105110002189	catalytic residue [active]
1105110002190	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1105110002191	trimer interface [polypeptide binding]; other site
1105110002192	active site
1105110002193	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
1105110002194	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1105110002195	tandem repeat interface [polypeptide binding]; other site
1105110002196	oligomer interface [polypeptide binding]; other site
1105110002197	active site residues [active]
1105110002198	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1105110002199	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1105110002200	catalytic residues [active]
1105110002201	Protocatechuate 3,4-dioxygenase beta subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PcaH; COG3485
1105110002202	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
1105110002203	active site
1105110002204	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1105110002205	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1105110002206	Iron permease FTR1 family; Region: FTR1; cl00475
1105110002207	Intracellular septation protein A [Cell division and chromosome partitioning]; Region: COG2917
1105110002208	Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823
1105110002209	BON domain; Region: BON; pfam04972
1105110002210	BON domain; Region: BON; pfam04972
1105110002211	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1105110002212	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1105110002213	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1105110002214	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1105110002215	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1105110002216	AmpG-like permease; Region: 2A0125; TIGR00901
1105110002217	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1105110002218	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105110002219	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110002220	Walker A/P-loop; other site
1105110002221	ATP binding site [chemical binding]; other site
1105110002222	Q-loop/lid; other site
1105110002223	ABC transporter signature motif; other site
1105110002224	Walker B; other site
1105110002225	D-loop; other site
1105110002226	H-loop/switch region; other site
1105110002227	Holliday junction resolvasome, helicase subunit [DNA replication, recombination, and repair]; Region: RuvB; COG2255
1105110002228	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110002229	Walker A motif; other site
1105110002230	ATP binding site [chemical binding]; other site
1105110002231	Walker B motif; other site
1105110002232	arginine finger; other site
1105110002233	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1105110002234	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1105110002235	RuvA N terminal domain; Region: RuvA_N; pfam01330
1105110002236	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1105110002237	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1105110002238	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1105110002239	prolyl-tRNA synthetase; Provisional; Region: PRK12325
1105110002240	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1105110002241	dimer interface [polypeptide binding]; other site
1105110002242	motif 1; other site
1105110002243	active site
1105110002244	motif 2; other site
1105110002245	motif 3; other site
1105110002246	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1105110002247	anticodon binding site; other site
1105110002248	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
1105110002249	GTP cyclohydrolase I; Provisional; Region: PLN03044
1105110002250	active site
1105110002251	Rickettsial palindromic element RPE4 domain; Region: RPE4; TIGR03777
1105110002252	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_19; cd04678
1105110002253	nudix motif; other site
1105110002254	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1105110002255	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1105110002256	Ligand binding site; other site
1105110002257	oligomer interface; other site
1105110002258	CTP synthetase; Validated; Region: pyrG; PRK05380
1105110002259	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1105110002260	Catalytic site [active]
1105110002261	active site
1105110002262	UTP binding site [chemical binding]; other site
1105110002263	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1105110002264	active site
1105110002265	putative oxyanion hole; other site
1105110002266	catalytic triad [active]
1105110002267	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105110002268	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110002269	malate dehydrogenase; Reviewed; Region: PRK06223
1105110002270	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
1105110002271	NAD(P) binding site [chemical binding]; other site
1105110002272	dimer interface [polypeptide binding]; other site
1105110002273	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1105110002274	substrate binding site [chemical binding]; other site
1105110002275	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110002276	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105110002277	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
1105110002278	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1105110002279	Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor...; Region: Sec7; cd00171
1105110002280	active site/putative ARF binding site [active]
1105110002281	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1105110002282	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1105110002283	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1105110002284	putative NAD(P) binding site [chemical binding]; other site
1105110002285	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1105110002286	Predicted permeases [General function prediction only]; Region: COG0679
1105110002287	lysyl-tRNA synthetase; Reviewed; Region: lysK; PRK00750
1105110002288	catalytic core domain of  class I lysyl tRNA synthetase; Region: LysRS_core_class_I; cd00674
1105110002289	active site
1105110002290	HIGH motif; other site
1105110002291	KMSKS motif; other site
1105110002292	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1105110002293	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
1105110002294	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110002295	Walker A/P-loop; other site
1105110002296	ATP binding site [chemical binding]; other site
1105110002297	Q-loop/lid; other site
1105110002298	ABC transporter signature motif; other site
1105110002299	Walker B; other site
1105110002300	D-loop; other site
1105110002301	H-loop/switch region; other site
1105110002302	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
1105110002303	TM-ABC transporter signature motif; other site
1105110002304	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG2984
1105110002305	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1105110002306	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1105110002307	putative active site [active]
1105110002308	catalytic triad [active]
1105110002309	putative dimer interface [polypeptide binding]; other site
1105110002310	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06603
1105110002311	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1105110002312	NAD binding site [chemical binding]; other site
1105110002313	homotetramer interface [polypeptide binding]; other site
1105110002314	homodimer interface [polypeptide binding]; other site
1105110002315	substrate binding site [chemical binding]; other site
1105110002316	active site
1105110002317	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1105110002318	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1105110002319	active site
1105110002320	DNA binding site [nucleotide binding]
1105110002321	Int/Topo IB signature motif; other site
1105110002322	potential frameshift: common BLAST hit: gi|67458962|ref|YP_246586.1| phage protein
1105110002323	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4765
1105110002324	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1105110002325	O-Antigen ligase; Region: Wzy_C; pfam04932
1105110002326	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1105110002327	NADH dehydrogenase subunit B; Validated; Region: PRK06411
1105110002328	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
1105110002329	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1105110002330	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
1105110002331	catalytic site [active]
1105110002332	metal binding site [ion binding]; metal-binding site
1105110002333	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
1105110002334	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1105110002335	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1105110002336	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1105110002337	putative dimer interface [polypeptide binding]; other site
1105110002338	[2Fe-2S] cluster binding site [ion binding]; other site
1105110002339	hypothetical protein; Provisional; Region: PRK14388
1105110002340	YCII-related domain; Region: YCII; cl00999
1105110002341	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
1105110002342	active site
1105110002343	DNA binding site [nucleotide binding]
1105110002344	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1105110002345	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1105110002346	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1105110002347	RimM N-terminal domain; Region: RimM; pfam01782
1105110002348	PRC-barrel domain; Region: PRC; pfam05239
1105110002349	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1105110002350	potential frameshift: common BLAST hit: gi|157825605|ref|YP_001493325.1| outer membrane assembly protein
1105110002351	potential frameshift: common BLAST hit: gi|350273412|ref|YP_004884725.1| putative lyase
1105110002352	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
1105110002353	UbiA prenyltransferase family; Region: UbiA; pfam01040
1105110002354	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1105110002355	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1105110002356	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105110002357	RNA binding surface [nucleotide binding]; other site
1105110002358	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1105110002359	ABC transporter signature motif; other site
1105110002360	Walker B; other site
1105110002361	D-loop; other site
1105110002362	H-loop/switch region; other site
1105110002363	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1105110002364	This family is most closely related to the GT1 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core; Region: GT1_WavL_like; cd03819
1105110002365	putative ADP-binding pocket [chemical binding]; other site
1105110002366	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1105110002367	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1105110002368	catalytic site [active]
1105110002369	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105110002370	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
1105110002371	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1105110002372	HlyD family secretion protein; Region: HlyD_3; pfam13437
1105110002373	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105110002374	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1105110002375	active site
1105110002376	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105110002377	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1105110002378	active site
1105110002379	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1105110002380	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1105110002381	active site
1105110002382	homodimer interface [polypeptide binding]; other site
1105110002383	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
1105110002384	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1105110002385	NAD(P) binding site [chemical binding]; other site
1105110002386	homodimer interface [polypeptide binding]; other site
1105110002387	substrate binding site [chemical binding]; other site
1105110002388	active site
1105110002389	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
1105110002390	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
1105110002391	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1105110002392	NADP binding site [chemical binding]; other site
1105110002393	active site
1105110002394	putative substrate binding site [chemical binding]; other site
1105110002395	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
1105110002396	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1105110002397	addiction module antidote protein, HigA family; Region: antidote_HigA; TIGR02607
1105110002398	non-specific DNA binding site [nucleotide binding]; other site
1105110002399	salt bridge; other site
1105110002400	sequence-specific DNA binding site [nucleotide binding]; other site
1105110002401	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1105110002402	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1105110002403	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1105110002404	Sulfatase; Region: Sulfatase; pfam00884
1105110002405	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105110002406	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1105110002407	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1105110002408	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1105110002409	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1105110002410	dimer interface [polypeptide binding]; other site
1105110002411	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1105110002412	catalytic triad [active]
1105110002413	peroxidatic and resolving cysteines [active]
1105110002414	DNA protecting protein DprA; Region: dprA; TIGR00732
1105110002415	potential frameshift: common BLAST hit: gi|67458923|ref|YP_246547.1| DNA processing protein DprA
1105110002416	DNA topoisomerase I; Validated; Region: PRK06599
1105110002417	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1105110002418	active site
1105110002419	interdomain interaction site; other site
1105110002420	putative metal-binding site [ion binding]; other site
1105110002421	nucleotide binding site [chemical binding]; other site
1105110002422	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1105110002423	domain I; other site
1105110002424	DNA binding groove [nucleotide binding]
1105110002425	phosphate binding site [ion binding]; other site
1105110002426	domain II; other site
1105110002427	domain III; other site
1105110002428	nucleotide binding site [chemical binding]; other site
1105110002429	catalytic site [active]
1105110002430	domain IV; other site
1105110002431	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1105110002432	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1105110002433	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1105110002434	glutamyl-tRNA synthetase; Provisional; Region: PRK12558
1105110002435	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105110002436	HIGH motif; other site
1105110002437	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105110002438	active site
1105110002439	KMSKS motif; other site
1105110002440	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cl00238
1105110002441	putative iron binding site [ion binding]; other site
1105110002442	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1105110002443	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1105110002444	dimerization interface [polypeptide binding]; other site
1105110002445	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1105110002446	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1105110002447	potential frameshift: common BLAST hit: gi|157827341|ref|YP_001496405.1| Mg chelatase-like protein
1105110002448	potential frameshift: common BLAST hit: gi|67458910|ref|YP_246534.1| Mg chelatase-like protein
1105110002449	potential frameshift: common BLAST hit: gi|91205630|ref|YP_537985.1| Mg chelatase-like protein
1105110002450	potential frameshift: common BLAST hit: gi|91205630|ref|YP_537985.1| Mg chelatase-like protein
1105110002451	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1105110002452	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105110002453	Walker A motif; other site
1105110002454	ATP binding site [chemical binding]; other site
1105110002455	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1105110002456	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1105110002457	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1105110002458	active site
1105110002459	HslU subunit interaction site [polypeptide binding]; other site
1105110002460	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
1105110002461	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
1105110002462	nucleotide binding site/active site [active]
1105110002463	HIT family signature motif; other site
1105110002464	catalytic residue [active]
1105110002465	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1105110002466	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1105110002467	type I secretion system ABC transporter, PrtD family; Region: type_I_sec_PrtD; TIGR01842
1105110002468	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
1105110002469	Walker A/P-loop; other site
1105110002470	ATP binding site [chemical binding]; other site
1105110002471	Q-loop/lid; other site
1105110002472	ABC transporter signature motif; other site
1105110002473	Walker B; other site
1105110002474	D-loop; other site
1105110002475	H-loop/switch region; other site
1105110002476	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1105110002477	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
1105110002478	HlyD family secretion protein; Region: HlyD_3; pfam13437
1105110002479	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105110002480	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105110002481	putative substrate translocation pore; other site
1105110002482	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105110002483	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1105110002484	Zn2+ binding site [ion binding]; other site
1105110002485	Mg2+ binding site [ion binding]; other site
1105110002486	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1105110002487	TolR protein; Region: tolR; TIGR02801
1105110002488	TolQ protein; Region: tolQ; TIGR02796
1105110002489	potential frameshift: common BLAST hit: gi|67458892|ref|YP_246516.1| ABC transporter ATP-binding protein
1105110002490	potential frameshift: common BLAST hit: gi|157827460|ref|YP_001496524.1| ABC transporter ATP-binding protein
1105110002491	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1105110002492	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1105110002493	dimer interface [polypeptide binding]; other site
1105110002494	motif 1; other site
1105110002495	active site
1105110002496	motif 2; other site
1105110002497	motif 3; other site
1105110002498	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1105110002499	anticodon binding site; other site
1105110002500	amino acid transporter; Region: 2A0306; TIGR00909
1105110002501	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1105110002502	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1105110002503	Ligand Binding Site [chemical binding]; other site
1105110002504	Cytochrome oxidase assembly factor [Posttranslational modification, protein turnover, chaperones]; Region: COX11; COG3175
1105110002505	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1105110002506	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1105110002507	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1105110002508	DNA binding residues [nucleotide binding]
1105110002509	translocation protein TolB; Provisional; Region: tolB; PRK05137
1105110002510	TolB amino-terminal domain; Region: TolB_N; pfam04052
1105110002511	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1105110002512	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1105110002513	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
1105110002514	Protein of unknown function DUF45; Region: DUF45; pfam01863
1105110002515	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1105110002516	Peptidase family M23; Region: Peptidase_M23; pfam01551
1105110002517	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
1105110002518	Fic/DOC family; Region: Fic; pfam02661
1105110002519	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
1105110002520	putative active site [active]
1105110002521	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1105110002522	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1105110002523	MutS domain I; Region: MutS_I; pfam01624
1105110002524	MutS domain II; Region: MutS_II; pfam05188
1105110002525	MutS domain III; Region: MutS_III; pfam05192
1105110002526	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1105110002527	Walker A/P-loop; other site
1105110002528	ATP binding site [chemical binding]; other site
1105110002529	Q-loop/lid; other site
1105110002530	ABC transporter signature motif; other site
1105110002531	Walker B; other site
1105110002532	D-loop; other site
1105110002533	H-loop/switch region; other site
1105110002534	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1105110002535	active site
1105110002536	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105110002537	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105110002538	Putative phage tail protein; Region: Phage-tail_3; pfam13550
1105110002539	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105110002540	PemK-like protein; Region: PemK; pfam02452
1105110002541	potential frameshift: common BLAST hit: gi|67459085|ref|YP_246709.1| cell surface antigen Sca3
1105110002542	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
1105110002543	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1105110002544	type IV secretion system component VirD4; Provisional; Region: PRK13897
1105110002545	The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome. They contain an ATP binding domain. VirD4 is involved in DNA transfer...; Region: TraG_VirD4; cd01126
1105110002546	Walker A motif; other site
1105110002547	ATP binding site [chemical binding]; other site
1105110002548	Walker B motif; other site
1105110002549	type IV secretion system ATPase VirB11; Provisional; Region: PRK13900
1105110002550	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1105110002551	Walker A motif; other site
1105110002552	hexamer interface [polypeptide binding]; other site
1105110002553	ATP binding site [chemical binding]; other site
1105110002554	Walker B motif; other site
1105110002555	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
1105110002556	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
1105110002557	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1105110002558	Protein of unknown function (DUF2706); Region: DUF2706; pfam10913
1105110002559	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1105110002560	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1105110002561	VirB7 interaction site; other site
1105110002562	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK07375
1105110002563	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK06591
1105110002564	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105110002565	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK06589
1105110002566	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105110002567	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1105110002568	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK06588
1105110002569	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105110002570	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
1105110002571	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1105110002572	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1105110002573	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1105110002574	Phage capsid family; Region: Phage_capsid; pfam05065
1105110002575	GTP-binding protein LepA; Provisional; Region: PRK05433
1105110002576	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1105110002577	G1 box; other site
1105110002578	putative GEF interaction site [polypeptide binding]; other site
1105110002579	GTP/Mg2+ binding site [chemical binding]; other site
1105110002580	Switch I region; other site
1105110002581	G2 box; other site
1105110002582	G3 box; other site
1105110002583	Switch II region; other site
1105110002584	G4 box; other site
1105110002585	G5 box; other site
1105110002586	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1105110002587	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1105110002588	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1105110002589	PCRF domain; Region: PCRF; pfam03462
1105110002590	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1105110002591	RF-1 domain; Region: RF-1; pfam00472
1105110002592	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1105110002593	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110002594	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1105110002595	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1105110002596	putative dimer interface [polypeptide binding]; other site
1105110002597	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
1105110002598	Cytochrome c; Region: Cytochrom_C; cl11414
1105110002599	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
1105110002600	Qi binding site; other site
1105110002601	intrachain domain interface; other site
1105110002602	interchain domain interface [polypeptide binding]; other site
1105110002603	cytochrome b; Provisional; Region: CYTB; MTH00156
1105110002604	heme bH binding site [chemical binding]; other site
1105110002605	heme bL binding site [chemical binding]; other site
1105110002606	Qo binding site; other site
1105110002607	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cd00290
1105110002608	interchain domain interface [polypeptide binding]; other site
1105110002609	intrachain domain interface; other site
1105110002610	Qi binding site; other site
1105110002611	Qo binding site; other site
1105110002612	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105110002613	Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal; Region: UCR_Fe-S_N; pfam10399
1105110002614	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
1105110002615	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
1105110002616	[2Fe-2S] cluster binding site [ion binding]; other site
1105110002617	Protein of unknown function (DUF2670); Region: DUF2670; pfam10875
1105110002618	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12507
1105110002619	Predicted subunit of the Multisubunit Na+/H+ antiporter [Inorganic ion transport and metabolism]; Region: COG1563
1105110002620	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
1105110002621	putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12674
1105110002622	isocitrate dehydrogenase; Validated; Region: PRK09222
1105110002623	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1105110002624	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: HlpA; COG2825
1105110002625	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1105110002626	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1105110002627	G1 box; other site
1105110002628	putative GEF interaction site [polypeptide binding]; other site
1105110002629	GTP/Mg2+ binding site [chemical binding]; other site
1105110002630	Switch I region; other site
1105110002631	G2 box; other site
1105110002632	G3 box; other site
1105110002633	Switch II region; other site
1105110002634	G4 box; other site
1105110002635	G5 box; other site
1105110002636	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1105110002637	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1105110002638	pyruvate dehydrogenase subunit beta; Validated; Region: PRK09212
1105110002639	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1105110002640	alpha subunit interface [polypeptide binding]; other site
1105110002641	TPP binding site [chemical binding]; other site
1105110002642	heterodimer interface [polypeptide binding]; other site
1105110002643	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1105110002644	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
1105110002645	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1105110002646	tetramer interface [polypeptide binding]; other site
1105110002647	TPP-binding site [chemical binding]; other site
1105110002648	heterodimer interface [polypeptide binding]; other site
1105110002649	phosphorylation loop region [posttranslational modification]
1105110002650	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1105110002651	putative catalytic site [active]
1105110002652	putative phosphate binding site [ion binding]; other site
1105110002653	active site
1105110002654	metal binding site A [ion binding]; metal-binding site
1105110002655	DNA binding site [nucleotide binding]
1105110002656	putative AP binding site [nucleotide binding]; other site
1105110002657	putative metal binding site B [ion binding]; other site
1105110002658	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1105110002659	Beta-lactamase; Region: Beta-lactamase; pfam00144
1105110002660	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1105110002661	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105110002662	RNA binding surface [nucleotide binding]; other site
1105110002663	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1105110002664	active site
1105110002665	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
1105110002666	Cytochrome oxidase assembly protein; Region: COX15-CtaA; cl15852
1105110002667	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105110002668	RNA binding site [nucleotide binding]; other site
1105110002669	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105110002670	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
1105110002671	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1105110002672	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1105110002673	Cytochrome c2 [Energy production and conversion]; Region: COG3474
1105110002674	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1105110002675	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105110002676	cell division protein FtsA; Region: ftsA; TIGR01174
1105110002677	Cell division protein FtsA; Region: FtsA; smart00842
1105110002678	Cell division protein FtsA; Region: FtsA; pfam14450
1105110002679	Cell division protein FtsQ; Region: FtsQ; pfam03799
1105110002680	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1105110002681	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1105110002682	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1105110002683	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1105110002684	FAD binding domain; Region: FAD_binding_4; pfam01565
1105110002685	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1105110002686	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1105110002687	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1105110002688	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105110002689	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105110002690	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1105110002691	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
1105110002692	C2 domain; Region: C2; cl14603
1105110002693	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105110002694	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105110002695	potential frameshift: common BLAST hit: gi|157825454|ref|YP_001493174.1| multidrug resistance protein A
1105110002696	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1105110002697	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1105110002698	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
1105110002699	Domain of unknown function (DUF2610); Region: DUF2610; pfam11020
1105110002700	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1105110002701	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
1105110002702	active site
1105110002703	elongation factor P; Validated; Region: PRK00529
1105110002704	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1105110002705	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1105110002706	RNA binding site [nucleotide binding]; other site
1105110002707	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1105110002708	RNA binding site [nucleotide binding]; other site
1105110002709	response regulator PleD; Reviewed; Region: pleD; PRK09581
1105110002710	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105110002711	active site
1105110002712	phosphorylation site [posttranslational modification]
1105110002713	intermolecular recognition site; other site
1105110002714	dimerization interface [polypeptide binding]; other site
1105110002715	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105110002716	active site
1105110002717	phosphorylation site [posttranslational modification]
1105110002718	intermolecular recognition site; other site
1105110002719	dimerization interface [polypeptide binding]; other site
1105110002720	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1105110002721	metal binding site [ion binding]; metal-binding site
1105110002722	active site
1105110002723	I-site; other site
1105110002724	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1105110002725	putative active site [active]
1105110002726	Ap4A binding site [chemical binding]; other site
1105110002727	nudix motif; other site
1105110002728	putative metal binding site [ion binding]; other site
1105110002729	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH_subfamily_a; cd00913
1105110002730	aromatic arch; other site
1105110002731	DCoH dimer interaction site [polypeptide binding]; other site
1105110002732	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
1105110002733	DCoH tetramer interaction site [polypeptide binding]; other site
1105110002734	substrate binding site [chemical binding]; other site
1105110002735	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
1105110002736	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
1105110002737	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1105110002738	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1105110002739	23S rRNA interface [nucleotide binding]; other site
1105110002740	L3 interface [polypeptide binding]; other site
1105110002741	FOG: WD40-like repeat [Function unknown]; Region: COG1520
1105110002742	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1105110002743	Trp docking motif [polypeptide binding]; other site
1105110002744	Protein of unknown function (DUF2659); Region: DUF2659; pfam10858
1105110002745	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1105110002746	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1105110002747	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1105110002748	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105110002749	dimer interface [polypeptide binding]; other site
1105110002750	phosphorylation site [posttranslational modification]
1105110002751	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105110002752	ATP binding site [chemical binding]; other site
1105110002753	Mg2+ binding site [ion binding]; other site
1105110002754	G-X-G motif; other site
1105110002755	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1105110002756	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1105110002757	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1105110002758	protein binding site [polypeptide binding]; other site
1105110002759	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1105110002760	Catalytic dyad [active]
1105110002761	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1105110002762	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105110002763	ATP binding site [chemical binding]; other site
1105110002764	Mg2+ binding site [ion binding]; other site
1105110002765	G-X-G motif; other site
1105110002766	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1105110002767	anchoring element; other site
1105110002768	dimer interface [polypeptide binding]; other site
1105110002769	ATP binding site [chemical binding]; other site
1105110002770	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1105110002771	active site
1105110002772	metal binding site [ion binding]; metal-binding site
1105110002773	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1105110002774	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105110002775	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105110002776	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1105110002777	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3827
1105110002778	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1105110002779	Protein of unknown function (DUF2660); Region: DUF2660; pfam10859
1105110002780	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310); Region: DUF2310; cl02380
1105110002781	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1105110002782	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1105110002783	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1105110002784	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1105110002785	active site
1105110002786	dimer interface [polypeptide binding]; other site
1105110002787	motif 1; other site
1105110002788	motif 2; other site
1105110002789	motif 3; other site
1105110002790	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1105110002791	anticodon binding site; other site
1105110002792	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1105110002793	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1105110002794	ATP binding site [chemical binding]; other site
1105110002795	active site
1105110002796	substrate binding site [chemical binding]; other site
1105110002797	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1105110002798	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1105110002799	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1105110002800	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105110002801	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1105110002802	putative metal binding site; other site
1105110002803	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1105110002804	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1105110002805	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1105110002806	Protein of unknown function (DUF2671); Region: DUF2671; pfam10877
1105110002807	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1105110002808	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105110002809	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110002810	Walker A/P-loop; other site
1105110002811	ATP binding site [chemical binding]; other site
1105110002812	Q-loop/lid; other site
1105110002813	ABC transporter signature motif; other site
1105110002814	Walker B; other site
1105110002815	D-loop; other site
1105110002816	H-loop/switch region; other site
1105110002817	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105110002818	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105110002819	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105110002820	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: PRK01424
1105110002821	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1105110002822	Predicted ATPase [General function prediction only]; Region: COG1485
1105110002823	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1105110002824	Walker A motif; other site
1105110002825	ATP binding site [chemical binding]; other site
1105110002826	Walker B motif; other site
1105110002827	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110002828	potential frameshift: common BLAST hit: gi|374319001|ref|YP_005065499.1| capsular polysaccharide biosynthesis protein
1105110002829	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1105110002830	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1105110002831	substrate binding site [chemical binding]; other site
1105110002832	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1105110002833	active site
1105110002834	substrate binding site [chemical binding]; other site
1105110002835	cosubstrate binding site; other site
1105110002836	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1105110002837	active site
1105110002838	catalytic residues [active]
1105110002839	metal binding site [ion binding]; metal-binding site
1105110002840	Iron-sulphur cluster assembly; Region: Fe-S_assembly; cl01123
1105110002841	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1105110002842	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1105110002843	DNA gyrase subunit A; Validated; Region: PRK05560
1105110002844	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1105110002845	CAP-like domain; other site
1105110002846	active site
1105110002847	primary dimer interface [polypeptide binding]; other site
1105110002848	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105110002849	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105110002850	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105110002851	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105110002852	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105110002853	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
1105110002854	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105110002855	Walker A/P-loop; other site
1105110002856	ATP binding site [chemical binding]; other site
1105110002857	Q-loop/lid; other site
1105110002858	ABC transporter signature motif; other site
1105110002859	Walker B; other site
1105110002860	D-loop; other site
1105110002861	H-loop/switch region; other site
1105110002862	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1105110002863	GSH binding site [chemical binding]; other site
1105110002864	catalytic residues [active]
1105110002865	excinuclease ABC subunit B; Provisional; Region: PRK05298
1105110002866	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105110002867	ATP binding site [chemical binding]; other site
1105110002868	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105110002869	nucleotide binding region [chemical binding]; other site
1105110002870	ATP-binding site [chemical binding]; other site
1105110002871	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1105110002872	UvrB/uvrC motif; Region: UVR; pfam02151
1105110002873	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1105110002874	RNA/DNA hybrid binding site [nucleotide binding]; other site
1105110002875	active site
1105110002876	co-chaperone HscB; Provisional; Region: hscB; PRK01356
1105110002877	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1105110002878	HSP70 interaction site [polypeptide binding]; other site
1105110002879	chaperone protein HscA; Provisional; Region: hscA; PRK01433
1105110002880	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1105110002881	nucleotide binding site [chemical binding]; other site
1105110002882	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1105110002883	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1105110002884	catalytic loop [active]
1105110002885	iron binding site [ion binding]; other site
1105110002886	TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358
1105110002887	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1105110002888	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1105110002889	Ligand Binding Site [chemical binding]; other site
1105110002890	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell envelope biogenesis, outer membrane]; Region: PbpC; COG4953
1105110002891	Transglycosylase; Region: Transgly; pfam00912
1105110002892	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1105110002893	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1105110002894	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1105110002895	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1105110002896	trimer interface [polypeptide binding]; other site
1105110002897	active site
1105110002898	substrate binding site [chemical binding]; other site
1105110002899	CoA binding site [chemical binding]; other site
1105110002900	MJ0042 family finger-like domain; Region: MJ0042_CXXC; TIGR02098
1105110002901	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1105110002902	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1105110002903	trimer interface [polypeptide binding]; other site
1105110002904	active site
1105110002905	substrate binding site [chemical binding]; other site
1105110002906	CoA binding site [chemical binding]; other site
1105110002907	Type IV secretory pathway, VirB2 components (pilins) [Intracellular trafficking and secretion]; Region: VirB2; COG3838
1105110002908	Cytochrome c oxidase subunit III.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_III; cd01665
1105110002909	Subunit III/VIIa interface [polypeptide binding]; other site
1105110002910	Phospholipid binding site [chemical binding]; other site
1105110002911	Subunit I/III interface [polypeptide binding]; other site
1105110002912	Subunit III/VIb interface [polypeptide binding]; other site
1105110002913	Subunit III/VIa interface; other site
1105110002914	Subunit III/Vb interface [polypeptide binding]; other site
1105110002915	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
1105110002916	diiron binding motif [ion binding]; other site
1105110002917	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK06585
1105110002918	Lipopolysaccharide-assembly; Region: LptE; cl01125
1105110002919	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110002920	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1105110002921	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1105110002922	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1105110002923	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1105110002924	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1105110002925	nucleotide binding site [chemical binding]; other site
1105110002926	chaperone protein DnaJ; Provisional; Region: PRK14300
1105110002927	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1105110002928	HSP70 interaction site [polypeptide binding]; other site
1105110002929	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1105110002930	substrate binding site [polypeptide binding]; other site
1105110002931	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1105110002932	Zn binding sites [ion binding]; other site
1105110002933	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1105110002934	dimer interface [polypeptide binding]; other site
1105110002935	ChaB; Region: ChaB; cl01887
1105110002936	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1105110002937	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1105110002938	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1105110002939	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1105110002940	Walker A/P-loop; other site
1105110002941	ATP binding site [chemical binding]; other site
1105110002942	Q-loop/lid; other site
1105110002943	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1105110002944	ABC transporter signature motif; other site
1105110002945	Walker B; other site
1105110002946	D-loop; other site
1105110002947	H-loop/switch region; other site
1105110002948	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1105110002949	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1105110002950	active site
1105110002951	Zn binding site [ion binding]; other site
1105110002952	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1105110002953	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1105110002954	TPP-binding site [chemical binding]; other site
1105110002955	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1105110002956	dimer interface [polypeptide binding]; other site
1105110002957	PYR/PP interface [polypeptide binding]; other site
1105110002958	TPP binding site [chemical binding]; other site
1105110002959	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1105110002960	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1105110002961	E3 interaction surface; other site
1105110002962	lipoyl attachment site [posttranslational modification]; other site
1105110002963	e3 binding domain; Region: E3_binding; pfam02817
1105110002964	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1105110002965	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
1105110002966	active site
1105110002967	Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324
1105110002968	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1105110002969	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1105110002970	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110002971	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1105110002972	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
1105110002973	coproporphyrinogen III oxidase; Provisional; Region: PRK06582
1105110002974	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105110002975	FeS/SAM binding site; other site
1105110002976	HemN C-terminal domain; Region: HemN_C; pfam06969
1105110002977	potential frameshift: common BLAST hit: gi|91206182|ref|YP_538537.1| transposase
1105110002978	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1105110002979	potential frameshift: common BLAST hit: gi|67459496|ref|YP_247120.1| prolyl endopeptidase
1105110002980	potential frameshift: common BLAST hit: gi|67459496|ref|YP_247120.1| prolyl endopeptidase
1105110002981	potential frameshift: common BLAST hit: gi|15604049|ref|NP_220564.1| peptidase
1105110002982	signal recognition particle protein; Provisional; Region: PRK10867
1105110002983	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1105110002984	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1105110002985	P loop; other site
1105110002986	GTP binding site [chemical binding]; other site
1105110002987	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1105110002988	DNA polymerase III subunit delta'; Validated; Region: PRK06581
1105110002989	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1105110002990	IHF dimer interface [polypeptide binding]; other site
1105110002991	IHF - DNA interface [nucleotide binding]; other site
1105110002992	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1105110002993	Protein export membrane protein; Region: SecD_SecF; cl14618
1105110002994	Uncharacterized conserved protein [Function unknown]; Region: COG2155
1105110002995	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1105110002996	RNA methyltransferase, RsmE family; Region: TIGR00046
1105110002997	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105110002998	Uncharacterized conserved small protein [Function unknown]; Region: COG5508
1105110002999	Protein of unknown function (DUF1674); Region: DUF1674; pfam07896
1105110003000	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1105110003001	putative coenzyme Q binding site [chemical binding]; other site
1105110003002	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1105110003003	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105110003004	S-adenosylmethionine binding site [chemical binding]; other site
1105110003005	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1105110003006	putative RNA binding site [nucleotide binding]; other site
1105110003007	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
1105110003008	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1105110003009	active site
1105110003010	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1105110003011	protein binding site [polypeptide binding]; other site
1105110003012	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1105110003013	putative substrate binding region [chemical binding]; other site
1105110003014	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1105110003015	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105110003016	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105110003017	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105110003018	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105110003019	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105110003020	Surface antigen; Region: Bac_surface_Ag; pfam01103
1105110003021	Transposase IS200 like; Region: Y1_Tnp; cl00848
1105110003022	Protein of unknown function (DUF2674); Region: DUF2674; pfam10879
1105110003023	potential frameshift: common BLAST hit: gi|67459516|ref|YP_247140.1| multidrug resistance protein B
1105110003024	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK06580
1105110003025	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1105110003026	putative nucleotide binding site [chemical binding]; other site
1105110003027	uridine monophosphate binding site [chemical binding]; other site
1105110003028	homohexameric interface [polypeptide binding]; other site
1105110003029	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1105110003030	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1105110003031	hinge region; other site
1105110003032	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1105110003033	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1105110003034	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1105110003035	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1105110003036	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1105110003037	GatB domain; Region: GatB_Yqey; smart00845
1105110003038	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1105110003039	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1105110003040	substrate binding pocket [chemical binding]; other site
1105110003041	membrane-bound complex binding site; other site
1105110003042	hinge residues; other site
1105110003043	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
1105110003044	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1105110003045	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1105110003046	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1105110003047	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1105110003048	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1105110003049	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1105110003050	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1105110003051	dimer interface [polypeptide binding]; other site
1105110003052	anticodon binding site; other site
1105110003053	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1105110003054	homodimer interface [polypeptide binding]; other site
1105110003055	motif 1; other site
1105110003056	active site
1105110003057	motif 2; other site
1105110003058	GAD domain; Region: GAD; pfam02938
1105110003059	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1105110003060	active site
1105110003061	motif 3; other site
1105110003062	ATPase MipZ; Region: MipZ; pfam09140
1105110003063	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105110003064	P-loop; other site
1105110003065	Magnesium ion binding site [ion binding]; other site
1105110003066	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1105110003067	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1105110003068	interface (dimer of trimers) [polypeptide binding]; other site
1105110003069	Substrate-binding/catalytic site; other site
1105110003070	Zn-binding sites [ion binding]; other site
1105110003071	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105110003072	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1105110003073	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1105110003074	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1105110003075	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1105110003076	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1105110003077	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1105110003078	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1105110003079	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cl00162
1105110003080	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1105110003081	DNA binding site [nucleotide binding]
1105110003082	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1105110003083	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1105110003084	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1105110003085	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1105110003086	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1105110003087	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1105110003088	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1105110003089	RPB3 interaction site [polypeptide binding]; other site
1105110003090	RPB1 interaction site [polypeptide binding]; other site
1105110003091	RPB11 interaction site [polypeptide binding]; other site
1105110003092	RPB10 interaction site [polypeptide binding]; other site
1105110003093	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1105110003094	core dimer interface [polypeptide binding]; other site
1105110003095	peripheral dimer interface [polypeptide binding]; other site
1105110003096	L10 interface [polypeptide binding]; other site
1105110003097	L11 interface [polypeptide binding]; other site
1105110003098	putative EF-Tu interaction site [polypeptide binding]; other site
1105110003099	putative EF-G interaction site [polypeptide binding]; other site
1105110003100	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1105110003101	23S rRNA interface [nucleotide binding]; other site
1105110003102	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1105110003103	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1105110003104	mRNA/rRNA interface [nucleotide binding]; other site
1105110003105	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1105110003106	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1105110003107	23S rRNA interface [nucleotide binding]; other site
1105110003108	putative thiostrepton binding site; other site
1105110003109	L7/L12 interface [polypeptide binding]; other site
1105110003110	L25 interface [polypeptide binding]; other site
1105110003111	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1105110003112	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1105110003113	putative homodimer interface [polypeptide binding]; other site
1105110003114	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1105110003115	heterodimer interface [polypeptide binding]; other site
1105110003116	homodimer interface [polypeptide binding]; other site
1105110003117	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1105110003118	elongation factor G; Reviewed; Region: PRK00007
1105110003119	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1105110003120	G1 box; other site
1105110003121	putative GEF interaction site [polypeptide binding]; other site
1105110003122	GTP/Mg2+ binding site [chemical binding]; other site
1105110003123	Switch I region; other site
1105110003124	G2 box; other site
1105110003125	G3 box; other site
1105110003126	Switch II region; other site
1105110003127	G4 box; other site
1105110003128	G5 box; other site
1105110003129	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1105110003130	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1105110003131	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1105110003132	30S ribosomal protein S7; Validated; Region: PRK05302
1105110003133	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1105110003134	S17 interaction site [polypeptide binding]; other site
1105110003135	S8 interaction site; other site
1105110003136	16S rRNA interaction site [nucleotide binding]; other site
1105110003137	streptomycin interaction site [chemical binding]; other site
1105110003138	23S rRNA interaction site [nucleotide binding]; other site
1105110003139	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1105110003140	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1105110003141	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1105110003142	dimer interface [polypeptide binding]; other site
1105110003143	conserved gate region; other site
1105110003144	putative PBP binding loops; other site
1105110003145	ABC-ATPase subunit interface; other site
1105110003146	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK09078
1105110003147	L-aspartate oxidase; Provisional; Region: PRK06175
1105110003148	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1105110003149	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
1105110003150	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit-like; composed of predominantly uncharacterized bacterial proteins with similarity to the E. coli SdhD subunit. One characterized protein is the respiratory...; Region: SQR_TypeC_SdhD_like; cd03495
1105110003151	putative SdhC subunit interface [polypeptide binding]; other site
1105110003152	putative proximal heme binding site [chemical binding]; other site
1105110003153	putative Iron-sulfur protein interface [polypeptide binding]; other site
1105110003154	putative proximal quinone binding site; other site
1105110003155	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1105110003156	Iron-sulfur protein interface; other site
1105110003157	proximal quinone binding site [chemical binding]; other site
1105110003158	SdhD (CybS) interface [polypeptide binding]; other site
1105110003159	proximal heme binding site [chemical binding]; other site
1105110003160	hypothetical protein; Validated; Region: PRK01415
1105110003161	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1105110003162	active site residue [active]
1105110003163	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1105110003164	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1105110003165	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1105110003166	protein binding site [polypeptide binding]; other site
1105110003167	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1105110003168	protein binding site [polypeptide binding]; other site
1105110003169	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1105110003170	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1105110003171	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1105110003172	HflK protein; Region: hflK; TIGR01933
1105110003173	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1105110003174	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1105110003175	Walker A motif; other site
1105110003176	Predicted nucleoside-diphosphate-sugar epimerase [Cell envelope biogenesis, outer membrane]; Region: COG3660
1105110003177	Mitochondrial fission ELM1; Region: Mito_fiss_Elm1; pfam06258
1105110003178	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; cl17552
1105110003179	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; cl17552
1105110003180	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1105110003181	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1105110003182	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1105110003183	active site
1105110003184	putative DNA-binding cleft [nucleotide binding]; other site
1105110003185	dimer interface [polypeptide binding]; other site
1105110003186	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1105110003187	GTPase Era; Reviewed; Region: era; PRK00089
1105110003188	G1 box; other site
1105110003189	GTP/Mg2+ binding site [chemical binding]; other site
1105110003190	Switch I region; other site
1105110003191	G2 box; other site
1105110003192	Switch II region; other site
1105110003193	G3 box; other site
1105110003194	G4 box; other site
1105110003195	G5 box; other site
1105110003196	KH domain; Region: KH_2; pfam07650
1105110003197	ribonuclease III; Reviewed; Region: rnc; PRK00102
1105110003198	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1105110003199	dimerization interface [polypeptide binding]; other site
1105110003200	active site
1105110003201	metal binding site [ion binding]; metal-binding site
1105110003202	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1105110003203	dsRNA binding site [nucleotide binding]; other site
1105110003204	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1105110003205	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1105110003206	Catalytic site [active]
1105110003207	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1105110003208	NADH dehydrogenase I subunit F; Provisional; Region: PRK13596
1105110003209	SLBB domain; Region: SLBB; pfam10531
1105110003210	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928