-- dump date   	20140620_034530
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1105113000001	Ferredoxin [Energy production and conversion]; Region: COG1146
1105113000002	4Fe-4S binding domain; Region: Fer4; cl02805
1105113000003	heme exporter protein CcmC; Region: ccmC; TIGR01191
1105113000004	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1105113000005	nucleoside/Zn binding site; other site
1105113000006	dimer interface [polypeptide binding]; other site
1105113000007	catalytic motif [active]
1105113000008	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1105113000009	Cation efflux family; Region: Cation_efflux; cl00316
1105113000010	Surface antigen [Cell envelope biogenesis, outer membrane]; Region: LipA; COG4520
1105113000011	PhosphatidylEthanolamine-Binding Protein (PEBP) domain; Region: PEBP; cl00227
1105113000012	substrate binding site [chemical binding]; other site
1105113000013	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1105113000014	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1105113000015	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1105113000016	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1105113000017	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1105113000018	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1105113000019	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1105113000020	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1105113000021	dimer interface [polypeptide binding]; other site
1105113000022	ssDNA binding site [nucleotide binding]; other site
1105113000023	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1105113000024	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
1105113000025	hypothetical protein; Reviewed; Region: PRK01530
1105113000026	heat shock protein 90; Provisional; Region: PRK05218
1105113000027	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105113000028	ATP binding site [chemical binding]; other site
1105113000029	Mg2+ binding site [ion binding]; other site
1105113000030	G-X-G motif; other site
1105113000031	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1105113000032	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1105113000033	substrate-cofactor binding pocket; other site
1105113000034	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105113000035	catalytic residue [active]
1105113000036	trigger factor; Provisional; Region: tig; PRK01490
1105113000037	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1105113000038	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1105113000039	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1105113000040	GTP1/OBG; Region: GTP1_OBG; pfam01018
1105113000041	Obg GTPase; Region: Obg; cd01898
1105113000042	G1 box; other site
1105113000043	GTP/Mg2+ binding site [chemical binding]; other site
1105113000044	Switch I region; other site
1105113000045	G2 box; other site
1105113000046	G3 box; other site
1105113000047	Switch II region; other site
1105113000048	G4 box; other site
1105113000049	G5 box; other site
1105113000050	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1105113000051	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1105113000052	dimer interface [polypeptide binding]; other site
1105113000053	active site
1105113000054	citrylCoA binding site [chemical binding]; other site
1105113000055	NADH binding [chemical binding]; other site
1105113000056	cationic pore residues; other site
1105113000057	oxalacetate/citrate binding site [chemical binding]; other site
1105113000058	coenzyme A binding site [chemical binding]; other site
1105113000059	catalytic triad [active]
1105113000060	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
1105113000061	Fe-S cluster binding site [ion binding]; other site
1105113000062	active site
1105113000063	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1105113000064	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105113000065	RNA binding surface [nucleotide binding]; other site
1105113000066	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1105113000067	active site
1105113000068	bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase; Reviewed; Region: PRK01544
1105113000069	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113000070	S-adenosylmethionine binding site [chemical binding]; other site
1105113000071	Predicted S-adenosylmethionine-dependent methyltransferase [General function prediction only]; Region: COG0220
1105113000072	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1105113000073	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1105113000074	Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; Region: GlyS; COG0751
1105113000075	DALR anticodon binding domain; Region: DALR_1; pfam05746
1105113000076	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
1105113000077	motif 1; other site
1105113000078	dimer interface [polypeptide binding]; other site
1105113000079	active site
1105113000080	motif 2; other site
1105113000081	motif 3; other site
1105113000082	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1105113000083	oligomeric interface; other site
1105113000084	putative active site [active]
1105113000085	homodimer interface [polypeptide binding]; other site
1105113000086	prevent-host-death family protein; Region: phd_fam; TIGR01552
1105113000087	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
1105113000088	potential frameshift: common BLAST hit: gi|374319835|ref|YP_005066334.1| Proline/betaine transporter
1105113000089	potential frameshift: common BLAST hit: gi|374319835|ref|YP_005066334.1| Proline/betaine transporter
1105113000090	potential frameshift: common BLAST hit: gi|67459741|ref|YP_247365.1| proline/betaine transporter
1105113000091	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1105113000092	NAD(P) binding site [chemical binding]; other site
1105113000093	active site
1105113000094	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4391
1105113000095	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1105113000096	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105113000097	ATP binding site [chemical binding]; other site
1105113000098	Mg2+ binding site [ion binding]; other site
1105113000099	G-X-G motif; other site
1105113000100	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1105113000101	ATP binding site [chemical binding]; other site
1105113000102	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1105113000103	ribosomal protein L33, bacterial type; Region: rpmG_bact; TIGR01023
1105113000104	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1105113000105	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1105113000106	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1105113000107	amidase catalytic site [active]
1105113000108	Zn binding residues [ion binding]; other site
1105113000109	substrate binding site [chemical binding]; other site
1105113000110	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1105113000111	lipoate-protein ligase B; Provisional; Region: PRK14347
1105113000112	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1105113000113	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cl00630
1105113000114	putative active site [active]
1105113000115	Na+/H+ antiporter [Inorganic ion transport and metabolism]; Region: NhaA; COG3004
1105113000116	potential frameshift: common BLAST hit: gi|157827849|ref|YP_001496913.1| Type I restriction-modification system methyltransferase subunit
1105113000117	potential frameshift: common BLAST hit: gi|157827849|ref|YP_001496913.1| Type I restriction-modification system methyltransferase subunit
1105113000118	potential frameshift: common BLAST hit: gi|341584500|ref|YP_004764991.1| putative type I restriction enzyme S subunit
1105113000119	potential frameshift: common BLAST hit: gi|238651120|ref|YP_002916978.1| putative type I restriction enzyme S subunit
1105113000120	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1105113000121	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1105113000122	metal binding site [ion binding]; metal-binding site
1105113000123	dimer interface [polypeptide binding]; other site
1105113000124	DNA polymerase III subunit chi; Provisional; Region: PRK06646
1105113000125	Predicted permeases [General function prediction only]; Region: COG0795
1105113000126	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1105113000127	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
1105113000128	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
1105113000129	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1105113000130	active site
1105113000131	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1105113000132	putative hydrolase; Provisional; Region: PRK02113
1105113000133	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1105113000134	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113000135	Walker A/P-loop; other site
1105113000136	ATP binding site [chemical binding]; other site
1105113000137	Q-loop/lid; other site
1105113000138	ABC transporter signature motif; other site
1105113000139	Walker B; other site
1105113000140	D-loop; other site
1105113000141	H-loop/switch region; other site
1105113000142	Beta-lactamase; Region: Beta-lactamase; pfam00144
1105113000143	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1105113000144	Predicted aspartyl protease [General function prediction only]; Region: COG3577
1105113000145	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
1105113000146	catalytic motif [active]
1105113000147	Catalytic residue [active]
1105113000148	hypothetical protein; Validated; Region: PRK00153
1105113000149	DNA polymerase III subunits gamma and tau; Validated; Region: PRK06645
1105113000150	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113000151	Walker A motif; other site
1105113000152	ATP binding site [chemical binding]; other site
1105113000153	Walker B motif; other site
1105113000154	arginine finger; other site
1105113000155	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1105113000156	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1105113000157	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1105113000158	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1105113000159	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
1105113000160	ligand binding site [chemical binding]; other site
1105113000161	homodimer interface [polypeptide binding]; other site
1105113000162	NAD(P) binding site [chemical binding]; other site
1105113000163	trimer interface B [polypeptide binding]; other site
1105113000164	trimer interface A [polypeptide binding]; other site
1105113000165	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
1105113000166	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1105113000167	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1105113000168	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1105113000169	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1105113000170	Dolichol kinase [Lipid metabolism]; Region: SEC59; COG0170
1105113000171	DNA primase, catalytic core; Region: dnaG; TIGR01391
1105113000172	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1105113000173	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1105113000174	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1105113000175	active site
1105113000176	metal binding site [ion binding]; metal-binding site
1105113000177	interdomain interaction site; other site
1105113000178	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1105113000179	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1105113000180	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1105113000181	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1105113000182	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1105113000183	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1105113000184	DNA binding residues [nucleotide binding]
1105113000185	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1105113000186	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1105113000187	dimerization interface 3.5A [polypeptide binding]; other site
1105113000188	active site
1105113000189	potential frameshift: common BLAST hit: gi|67458439|ref|YP_246063.1| cell surface antigen-like protein Sca10
1105113000190	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1105113000191	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1105113000192	Colicin V production protein; Region: Colicin_V; pfam02674
1105113000193	Putative transcriptional regulator [Transcription]; Region: COG1678
1105113000194	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1105113000195	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1105113000196	Cu(I) binding site [ion binding]; other site
1105113000197	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1105113000198	Integrase core domain; Region: rve; pfam00665
1105113000199	Integrase core domain; Region: rve_3; pfam13683
1105113000200	Helix-turn-helix domain; Region: HTH_28; pfam13518
1105113000201	Winged helix-turn helix; Region: HTH_29; pfam13551
1105113000202	Dihydroneopterin aldolase; Region: FolB; smart00905
1105113000203	active site
1105113000204	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cl00233
1105113000205	TENA/THI-4/PQQC family; Region: TENA_THI-4; cl15243
1105113000206	Recombinational DNA repair ATPase (RecF pathway) [DNA replication, recombination, and repair]; Region: RecF; COG1195
1105113000207	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113000208	Walker A/P-loop; other site
1105113000209	ATP binding site [chemical binding]; other site
1105113000210	Q-loop/lid; other site
1105113000211	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113000212	ABC transporter signature motif; other site
1105113000213	Walker B; other site
1105113000214	D-loop; other site
1105113000215	H-loop/switch region; other site
1105113000216	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105113000217	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113000218	S-adenosylmethionine binding site [chemical binding]; other site
1105113000219	Predicted regulatory domain of a methyltransferase [General function prediction only]; Region: COG4797
1105113000220	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1105113000221	Transcriptional regulators, similar to M. xanthus CarD [Transcription]; Region: COG1329
1105113000222	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1105113000223	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
1105113000224	catalytic residues [active]
1105113000225	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5336
1105113000226	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1105113000227	ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Region: ATP_synt_6_or_A; TIGR01131
1105113000228	F0F1 ATP synthase subunit C; Validated; Region: PRK07558
1105113000229	F0F1 ATP synthase subunit B'; Validated; Region: PRK06569
1105113000230	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1105113000231	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1105113000232	F0F1 ATP synthase subunit B; Validated; Region: PRK06568
1105113000233	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105113000234	Competence protein; Region: Competence; pfam03772
1105113000235	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
1105113000236	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1105113000237	active site
1105113000238	NTP binding site [chemical binding]; other site
1105113000239	metal binding triad [ion binding]; metal-binding site
1105113000240	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1105113000241	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1105113000242	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1105113000243	intersubunit interface [polypeptide binding]; other site
1105113000244	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1105113000245	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
1105113000246	potential frameshift: common BLAST hit: gi|238650328|ref|YP_002916180.1| nifR3-like protein
1105113000247	potential frameshift: common BLAST hit: gi|238650328|ref|YP_002916180.1| nifR3-like protein
1105113000248	potential frameshift: common BLAST hit: gi|341583236|ref|YP_004763727.1| tRNA-dihydrouridine synthase
1105113000249	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1105113000250	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1105113000251	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1105113000252	trimer interface [polypeptide binding]; other site
1105113000253	active site
1105113000254	UDP-GlcNAc binding site [chemical binding]; other site
1105113000255	lipid binding site [chemical binding]; lipid-binding site
1105113000256	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1105113000257	Acyl-[acyl carrier protein]; Region: LpxA; COG1043
1105113000258	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1105113000259	active site
1105113000260	putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase; Validated; Region: PRK06567
1105113000261	FAD/NAD binding domain (electron transfer subunit) of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate...; Region: DHOD_e_trans_like; cd06192
1105113000262	FAD binding pocket [chemical binding]; other site
1105113000263	FAD binding motif [chemical binding]; other site
1105113000264	phosphate binding motif [ion binding]; other site
1105113000265	beta-alpha-beta structure motif; other site
1105113000266	NAD binding pocket [chemical binding]; other site
1105113000267	Iron coordination center [ion binding]; other site
1105113000268	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1105113000269	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1105113000270	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1105113000271	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1105113000272	Walker A/P-loop; other site
1105113000273	ATP binding site [chemical binding]; other site
1105113000274	Q-loop/lid; other site
1105113000275	ABC transporter signature motif; other site
1105113000276	Walker B; other site
1105113000277	D-loop; other site
1105113000278	H-loop/switch region; other site
1105113000279	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1105113000280	catalytic residues [active]
1105113000281	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1806
1105113000282	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1105113000283	substrate binding site [chemical binding]; other site
1105113000284	active site
1105113000285	ferrochelatase; Reviewed; Region: hemH; PRK00035
1105113000286	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1105113000287	C-terminal domain interface [polypeptide binding]; other site
1105113000288	active site
1105113000289	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1105113000290	active site
1105113000291	N-terminal domain interface [polypeptide binding]; other site
1105113000292	TIGR00701 family protein; Region: TIGR00701
1105113000293	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1105113000294	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1105113000295	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105113000296	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105113000297	putative substrate translocation pore; other site
1105113000298	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105113000299	TPR motif; other site
1105113000300	binding surface
1105113000301	potential frameshift: common BLAST hit: gi|374319835|ref|YP_005066334.1| Proline/betaine transporter
1105113000302	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1105113000303	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1105113000304	motif 1; other site
1105113000305	active site
1105113000306	motif 2; other site
1105113000307	motif 3; other site
1105113000308	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1105113000309	Autotransporter beta-domain; Region: Autotransporter; cl17461
1105113000310	Autotransporter beta-domain; Region: Autotransporter; cl17461
1105113000311	Protein of unknown function (DUF2748); Region: DUF2748; pfam10871
1105113000312	potential frameshift: common BLAST hit: gi|157825142|ref|YP_001492862.1| acetoacetyl-CoA reductase
1105113000313	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1105113000314	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113000315	Walker A motif; other site
1105113000316	ATP binding site [chemical binding]; other site
1105113000317	Walker B motif; other site
1105113000318	arginine finger; other site
1105113000319	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113000320	Walker A motif; other site
1105113000321	ATP binding site [chemical binding]; other site
1105113000322	Walker B motif; other site
1105113000323	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1105113000324	UGMP family protein; Validated; Region: PRK09604
1105113000325	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1105113000326	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
1105113000327	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1105113000328	Di-iron ligands [ion binding]; other site
1105113000329	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
1105113000330	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1105113000331	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1105113000332	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1105113000333	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1105113000334	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1105113000335	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1105113000336	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1105113000337	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1105113000338	Ligand Binding Site [chemical binding]; other site
1105113000339	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113000340	FtsH Extracellular; Region: FtsH_ext; pfam06480
1105113000341	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1105113000342	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113000343	Walker A motif; other site
1105113000344	ATP binding site [chemical binding]; other site
1105113000345	Walker B motif; other site
1105113000346	arginine finger; other site
1105113000347	Peptidase family M41; Region: Peptidase_M41; pfam01434
1105113000348	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1105113000349	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1105113000350	Protein of unknown function (DUF1311); Region: DUF1311; cl01530
1105113000351	Uncharacterized conserved protein [Function unknown]; Region: COG1565
1105113000352	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113000353	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1105113000354	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1105113000355	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1105113000356	membrane protein insertase; Provisional; Region: PRK01318
1105113000357	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1105113000358	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1105113000359	potential frameshift: common BLAST hit: gi|67458519|ref|YP_246143.1| tellurite resistance protein-like protein
1105113000360	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1105113000361	active site
1105113000362	catalytic residues [active]
1105113000363	metal binding site [ion binding]; metal-binding site
1105113000364	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105113000365	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1105113000366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105113000367	putative substrate translocation pore; other site
1105113000368	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1105113000369	active site
1105113000370	multimer interface [polypeptide binding]; other site
1105113000371	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1105113000372	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1105113000373	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1105113000374	potential frameshift: common BLAST hit: gi|157964123|ref|YP_001498947.1| 16S rRNA methyltransferase GidB
1105113000375	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1105113000376	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105113000377	P-loop; other site
1105113000378	Magnesium ion binding site [ion binding]; other site
1105113000379	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105113000380	Magnesium ion binding site [ion binding]; other site
1105113000381	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1105113000382	ParB-like nuclease domain; Region: ParB; smart00470
1105113000383	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1105113000384	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105113000385	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113000386	Walker A/P-loop; other site
1105113000387	ATP binding site [chemical binding]; other site
1105113000388	Q-loop/lid; other site
1105113000389	ABC transporter signature motif; other site
1105113000390	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105113000391	ABC transporter; Region: ABC_tran_2; pfam12848
1105113000392	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105113000393	Protein of unknown function (DUF2672); Region: DUF2672; pfam10878
1105113000394	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
1105113000395	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1105113000396	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1105113000397	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
1105113000398	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1105113000399	Zn2+ binding site [ion binding]; other site
1105113000400	Mg2+ binding site [ion binding]; other site
1105113000401	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1105113000402	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1105113000403	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
1105113000404	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1105113000405	active site
1105113000406	HIGH motif; other site
1105113000407	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105113000408	KMSK motif region; other site
1105113000409	tRNA binding surface [nucleotide binding]; other site
1105113000410	DALR anticodon binding domain; Region: DALR_1; smart00836
1105113000411	anticodon binding site; other site
1105113000412	Sporulation related domain; Region: SPOR; pfam05036
1105113000413	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
1105113000414	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1105113000415	CAP-like domain; other site
1105113000416	active site
1105113000417	primary dimer interface [polypeptide binding]; other site
1105113000418	Gram-negative porin; Region: Porin_4; pfam13609
1105113000419	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1105113000420	trimer interface [polypeptide binding]; other site
1105113000421	active site
1105113000422	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1105113000423	SecA binding site; other site
1105113000424	Preprotein binding site; other site
1105113000425	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1105113000426	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105113000427	active site
1105113000428	phosphorylation site [posttranslational modification]
1105113000429	intermolecular recognition site; other site
1105113000430	dimerization interface [polypeptide binding]; other site
1105113000431	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1105113000432	DNA binding site [nucleotide binding]
1105113000433	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1105113000434	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1105113000435	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1105113000436	Protein of unknown function (DUF1013); Region: DUF1013; cl11533
1105113000437	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
1105113000438	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1105113000439	Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047
1105113000440	EamA-like transporter family; Region: EamA; pfam00892
1105113000441	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1105113000442	EamA-like transporter family; Region: EamA; pfam00892
1105113000443	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105113000444	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105113000445	putative substrate translocation pore; other site
1105113000446	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
1105113000447	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
1105113000448	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105113000449	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1105113000450	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1105113000451	active site
1105113000452	HIGH motif; other site
1105113000453	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1105113000454	KMSKS motif; other site
1105113000455	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1105113000456	tRNA binding surface [nucleotide binding]; other site
1105113000457	anticodon binding site; other site
1105113000458	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1105113000459	rRNA interaction site [nucleotide binding]; other site
1105113000460	S8 interaction site; other site
1105113000461	putative laminin-1 binding site; other site
1105113000462	elongation factor Ts; Provisional; Region: tsf; PRK09377
1105113000463	UBA/TS-N domain; Region: UBA; pfam00627
1105113000464	Elongation factor TS; Region: EF_TS; pfam00889
1105113000465	Elongation factor TS; Region: EF_TS; pfam00889
1105113000466	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1105113000467	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113000468	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1105113000469	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
1105113000470	putative acyl-acceptor binding pocket; other site
1105113000471	aspartate aminotransferase; Provisional; Region: PRK05764
1105113000472	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1105113000473	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105113000474	homodimer interface [polypeptide binding]; other site
1105113000475	catalytic residue [active]
1105113000476	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
1105113000477	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
1105113000478	TPR repeat; Region: TPR_11; pfam13414
1105113000479	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1105113000480	binding surface
1105113000481	TPR motif; other site
1105113000482	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1105113000483	Methyltransferase domain; Region: Methyltransf_18; pfam12847
1105113000484	Surface lipoprotein [Cell envelope biogenesis, outer membrane]; Region: VacJ; COG2853
1105113000485	ABC-type transport system involved in resistance to organic solvents, auxiliary component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2D; COG2854
1105113000486	potential frameshift: common BLAST hit: gi|157964158|ref|YP_001498982.1| ribose-phosphate pyrophosphokinase
1105113000487	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113000488	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
1105113000489	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1105113000490	active site
1105113000491	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1105113000492	dimer interface [polypeptide binding]; other site
1105113000493	substrate binding site [chemical binding]; other site
1105113000494	catalytic residues [active]
1105113000495	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1105113000496	Permease; Region: Permease; pfam02405
1105113000497	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1105113000498	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113000499	Walker A/P-loop; other site
1105113000500	ATP binding site [chemical binding]; other site
1105113000501	Q-loop/lid; other site
1105113000502	ABC transporter signature motif; other site
1105113000503	Walker B; other site
1105113000504	D-loop; other site
1105113000505	H-loop/switch region; other site
1105113000506	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113000507	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113000508	Ribosomal protein L28 [Translation, ribosomal structure and biogenesis]; Region: RpmB; COG0227
1105113000509	50S ribosomal protein L31; Provisional; Region: PRK01397
1105113000510	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1105113000511	G1 box; other site
1105113000512	GTP/Mg2+ binding site [chemical binding]; other site
1105113000513	Switch I region; other site
1105113000514	G2 box; other site
1105113000515	G3 box; other site
1105113000516	Switch II region; other site
1105113000517	G4 box; other site
1105113000518	G5 box; other site
1105113000519	Acetylglutamate kinase [Amino acid transport and metabolism]; Region: ArgB; COG0548
1105113000520	nucleotide binding site [chemical binding]; other site
1105113000521	substrate binding site [chemical binding]; other site
1105113000522	type IV secretion system protein VirB3; Provisional; Region: PRK13899
1105113000523	type IV secretion system ATPase VirB4; Provisional; Region: PRK13898
1105113000524	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1105113000525	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113000526	Walker A/P-loop; other site
1105113000527	ATP binding site [chemical binding]; other site
1105113000528	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105113000529	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105113000530	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105113000531	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105113000532	Type IV secretory pathway, VirB6 components [Intracellular trafficking and secretion]; Region: VirB6; COG3704
1105113000533	potential frameshift: common BLAST hit: gi|67458488|ref|YP_246112.1| phosphate acetyltransferase
1105113000534	potential frameshift: common BLAST hit: gi|67458489|ref|YP_246113.1| acetate kinase
1105113000535	tRNA-(guanine-N1)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmD; COG0336
1105113000536	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1105113000537	hypothetical protein; Provisional; Region: PRK13694
1105113000538	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1105113000539	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1105113000540	Protein export membrane protein; Region: SecD_SecF; pfam02355
1105113000541	NADH dehydrogenase I subunit F; Provisional; Region: PRK13596
1105113000542	SLBB domain; Region: SLBB; pfam10531
1105113000543	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
1105113000544	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1105113000545	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1105113000546	Catalytic site [active]
1105113000547	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1105113000548	ribonuclease III; Reviewed; Region: rnc; PRK00102
1105113000549	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1105113000550	dimerization interface [polypeptide binding]; other site
1105113000551	active site
1105113000552	metal binding site [ion binding]; metal-binding site
1105113000553	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1105113000554	dsRNA binding site [nucleotide binding]; other site
1105113000555	GTPase Era; Provisional; Region: era; PRK15494
1105113000556	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113000557	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1105113000558	G1 box; other site
1105113000559	GTP/Mg2+ binding site [chemical binding]; other site
1105113000560	Switch I region; other site
1105113000561	G2 box; other site
1105113000562	Switch II region; other site
1105113000563	G3 box; other site
1105113000564	G4 box; other site
1105113000565	G5 box; other site
1105113000566	KH domain; Region: KH_2; pfam07650
1105113000567	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1105113000568	active site
1105113000569	putative DNA-binding cleft [nucleotide binding]; other site
1105113000570	dimer interface [polypeptide binding]; other site
1105113000571	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1105113000572	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1105113000573	nucleotidyltransferase substrate binding protein, HI0074 family; Region: HI0074; TIGR01987
1105113000574	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1105113000575	active site
1105113000576	NTP binding site [chemical binding]; other site
1105113000577	metal binding triad [ion binding]; metal-binding site
1105113000578	antibiotic binding site [chemical binding]; other site
1105113000579	Predicted nucleoside-diphosphate-sugar epimerase [Cell envelope biogenesis, outer membrane]; Region: COG3660
1105113000580	Mitochondrial fission ELM1; Region: Mito_fiss_Elm1; pfam06258
1105113000581	AAA domain; Region: AAA_31; pfam13614
1105113000582	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1105113000583	Walker A motif; other site
1105113000584	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1105113000585	HflK protein; Region: hflK; TIGR01933
1105113000586	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1105113000587	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1105113000588	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1105113000589	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1105113000590	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1105113000591	protein binding site [polypeptide binding]; other site
1105113000592	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1105113000593	protein binding site [polypeptide binding]; other site
1105113000594	hypothetical protein; Validated; Region: PRK01415
1105113000595	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1105113000596	active site residue [active]
1105113000597	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1105113000598	Iron-sulfur protein interface; other site
1105113000599	proximal quinone binding site [chemical binding]; other site
1105113000600	SdhD (CybS) interface [polypeptide binding]; other site
1105113000601	proximal heme binding site [chemical binding]; other site
1105113000602	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit-like; composed of predominantly uncharacterized bacterial proteins with similarity to the E. coli SdhD subunit. One characterized protein is the respiratory...; Region: SQR_TypeC_SdhD_like; cd03495
1105113000603	putative SdhC subunit interface [polypeptide binding]; other site
1105113000604	putative proximal heme binding site [chemical binding]; other site
1105113000605	putative Iron-sulfur protein interface [polypeptide binding]; other site
1105113000606	putative proximal quinone binding site; other site
1105113000607	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK09078
1105113000608	L-aspartate oxidase; Provisional; Region: PRK06175
1105113000609	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1105113000610	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1105113000611	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1105113000612	dimer interface [polypeptide binding]; other site
1105113000613	conserved gate region; other site
1105113000614	putative PBP binding loops; other site
1105113000615	ABC-ATPase subunit interface; other site
1105113000616	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1105113000617	S17 interaction site [polypeptide binding]; other site
1105113000618	S8 interaction site; other site
1105113000619	16S rRNA interaction site [nucleotide binding]; other site
1105113000620	streptomycin interaction site [chemical binding]; other site
1105113000621	23S rRNA interaction site [nucleotide binding]; other site
1105113000622	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1105113000623	30S ribosomal protein S7; Validated; Region: PRK05302
1105113000624	elongation factor G; Reviewed; Region: PRK00007
1105113000625	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1105113000626	G1 box; other site
1105113000627	putative GEF interaction site [polypeptide binding]; other site
1105113000628	GTP/Mg2+ binding site [chemical binding]; other site
1105113000629	Switch I region; other site
1105113000630	G2 box; other site
1105113000631	G3 box; other site
1105113000632	Switch II region; other site
1105113000633	G4 box; other site
1105113000634	G5 box; other site
1105113000635	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1105113000636	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1105113000637	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1105113000638	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1105113000639	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1105113000640	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1105113000641	putative homodimer interface [polypeptide binding]; other site
1105113000642	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1105113000643	heterodimer interface [polypeptide binding]; other site
1105113000644	homodimer interface [polypeptide binding]; other site
1105113000645	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1105113000646	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1105113000647	23S rRNA interface [nucleotide binding]; other site
1105113000648	putative thiostrepton binding site; other site
1105113000649	L7/L12 interface [polypeptide binding]; other site
1105113000650	L25 interface [polypeptide binding]; other site
1105113000651	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1105113000652	mRNA/rRNA interface [nucleotide binding]; other site
1105113000653	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1105113000654	23S rRNA interface [nucleotide binding]; other site
1105113000655	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1105113000656	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1105113000657	core dimer interface [polypeptide binding]; other site
1105113000658	peripheral dimer interface [polypeptide binding]; other site
1105113000659	L10 interface [polypeptide binding]; other site
1105113000660	L11 interface [polypeptide binding]; other site
1105113000661	putative EF-Tu interaction site [polypeptide binding]; other site
1105113000662	putative EF-G interaction site [polypeptide binding]; other site
1105113000663	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1105113000664	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1105113000665	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1105113000666	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1105113000667	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1105113000668	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1105113000669	RPB3 interaction site [polypeptide binding]; other site
1105113000670	RPB1 interaction site [polypeptide binding]; other site
1105113000671	RPB11 interaction site [polypeptide binding]; other site
1105113000672	RPB10 interaction site [polypeptide binding]; other site
1105113000673	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1105113000674	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1105113000675	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1105113000676	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1105113000677	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1105113000678	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1105113000679	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1105113000680	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1105113000681	DNA binding site [nucleotide binding]
1105113000682	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1105113000683	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113000684	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1105113000685	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1105113000686	interface (dimer of trimers) [polypeptide binding]; other site
1105113000687	Substrate-binding/catalytic site; other site
1105113000688	Zn-binding sites [ion binding]; other site
1105113000689	ATPase MipZ; Region: MipZ; pfam09140
1105113000690	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105113000691	P-loop; other site
1105113000692	Magnesium ion binding site [ion binding]; other site
1105113000693	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105113000694	Magnesium ion binding site [ion binding]; other site
1105113000695	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1105113000696	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1105113000697	dimer interface [polypeptide binding]; other site
1105113000698	anticodon binding site; other site
1105113000699	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1105113000700	homodimer interface [polypeptide binding]; other site
1105113000701	motif 1; other site
1105113000702	active site
1105113000703	motif 2; other site
1105113000704	GAD domain; Region: GAD; pfam02938
1105113000705	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1105113000706	active site
1105113000707	motif 3; other site
1105113000708	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1105113000709	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1105113000710	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1105113000711	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1105113000712	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1105113000713	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
1105113000714	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1105113000715	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1105113000716	substrate binding pocket [chemical binding]; other site
1105113000717	membrane-bound complex binding site; other site
1105113000718	hinge residues; other site
1105113000719	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1105113000720	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1105113000721	GatB domain; Region: GatB_Yqey; smart00845
1105113000722	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1105113000723	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1105113000724	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1105113000725	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1105113000726	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1105113000727	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1105113000728	hinge region; other site
1105113000729	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1105113000730	putative nucleotide binding site [chemical binding]; other site
1105113000731	uridine monophosphate binding site [chemical binding]; other site
1105113000732	homohexameric interface [polypeptide binding]; other site
1105113000733	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK06580
1105113000734	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1105113000735	potential frameshift: common BLAST hit: gi|157964224|ref|YP_001499048.1| MFS-type multidrug resistance protein B
1105113000736	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1105113000737	Protein of unknown function (DUF2674); Region: DUF2674; pfam10879
1105113000738	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1105113000739	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105113000740	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105113000741	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105113000742	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105113000743	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1105113000744	Surface antigen; Region: Bac_surface_Ag; pfam01103
1105113000745	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
1105113000746	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1105113000747	active site
1105113000748	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1105113000749	protein binding site [polypeptide binding]; other site
1105113000750	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1105113000751	putative substrate binding region [chemical binding]; other site
1105113000752	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
1105113000753	putative RNA binding site [nucleotide binding]; other site
1105113000754	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1105113000755	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113000756	S-adenosylmethionine binding site [chemical binding]; other site
1105113000757	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1105113000758	putative coenzyme Q binding site [chemical binding]; other site
1105113000759	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113000760	Uncharacterized conserved small protein [Function unknown]; Region: COG5508
1105113000761	Protein of unknown function (DUF1674); Region: DUF1674; pfam07896
1105113000762	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1105113000763	RNA methyltransferase, RsmE family; Region: TIGR00046
1105113000764	Uncharacterized conserved protein [Function unknown]; Region: COG2155
1105113000765	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1105113000766	Protein export membrane protein; Region: SecD_SecF; cl14618
1105113000767	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1105113000768	IHF dimer interface [polypeptide binding]; other site
1105113000769	IHF - DNA interface [nucleotide binding]; other site
1105113000770	DNA polymerase III subunit delta'; Validated; Region: PRK06581
1105113000771	signal recognition particle protein; Provisional; Region: PRK10867
1105113000772	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1105113000773	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1105113000774	P loop; other site
1105113000775	GTP binding site [chemical binding]; other site
1105113000776	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1105113000777	potential frameshift: common BLAST hit: gi|51473374|ref|YP_067131.1| post-proline cleaving enzyme
1105113000778	potential frameshift: common BLAST hit: gi|15604049|ref|NP_220564.1| peptidase
1105113000779	potential frameshift: common BLAST hit: gi|67459496|ref|YP_247120.1| prolyl endopeptidase
1105113000780	coproporphyrinogen III oxidase; Provisional; Region: PRK06582
1105113000781	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105113000782	FeS/SAM binding site; other site
1105113000783	HemN C-terminal domain; Region: HemN_C; pfam06969
1105113000784	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529
1105113000785	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105113000786	potential frameshift: common BLAST hit: gi|157826898|ref|YP_001495962.1| cephalosporin hydroxylase
1105113000787	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1105113000788	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1105113000789	Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324
1105113000790	6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism]; Region: COG0720
1105113000791	active site
1105113000792	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1105113000793	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1105113000794	E3 interaction surface; other site
1105113000795	lipoyl attachment site [posttranslational modification]; other site
1105113000796	e3 binding domain; Region: E3_binding; pfam02817
1105113000797	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1105113000798	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1105113000799	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1105113000800	TPP-binding site [chemical binding]; other site
1105113000801	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1105113000802	dimer interface [polypeptide binding]; other site
1105113000803	PYR/PP interface [polypeptide binding]; other site
1105113000804	TPP binding site [chemical binding]; other site
1105113000805	potential frameshift: common BLAST hit: gi|350273234|ref|YP_004884547.1| thermostable carboxypeptidase
1105113000806	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1105113000807	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1105113000808	Walker A/P-loop; other site
1105113000809	ATP binding site [chemical binding]; other site
1105113000810	Q-loop/lid; other site
1105113000811	Allexivirus 40kDa protein; Region: Allexi_40kDa; pfam05549
1105113000812	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1105113000813	ABC transporter signature motif; other site
1105113000814	Walker B; other site
1105113000815	D-loop; other site
1105113000816	H-loop/switch region; other site
1105113000817	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1105113000818	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1105113000819	ChaB; Region: ChaB; cl01887
1105113000820	ChaB; Region: ChaB; cl01887
1105113000821	chaperone protein DnaJ; Provisional; Region: PRK14300
1105113000822	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1105113000823	HSP70 interaction site [polypeptide binding]; other site
1105113000824	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1105113000825	substrate binding site [polypeptide binding]; other site
1105113000826	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1105113000827	Zn binding sites [ion binding]; other site
1105113000828	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1105113000829	dimer interface [polypeptide binding]; other site
1105113000830	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1105113000831	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1105113000832	nucleotide binding site [chemical binding]; other site
1105113000833	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1105113000834	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1105113000835	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1105113000836	Lipopolysaccharide-assembly; Region: LptE; cl01125
1105113000837	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK06585
1105113000838	Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042
1105113000839	diiron binding motif [ion binding]; other site
1105113000840	Cytochrome c oxidase subunit III.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_III; cd01665
1105113000841	Subunit III/VIIa interface [polypeptide binding]; other site
1105113000842	Phospholipid binding site [chemical binding]; other site
1105113000843	Subunit I/III interface [polypeptide binding]; other site
1105113000844	Subunit III/VIb interface [polypeptide binding]; other site
1105113000845	Subunit III/VIa interface; other site
1105113000846	Subunit III/Vb interface [polypeptide binding]; other site
1105113000847	Type IV secretory pathway, VirB2 components (pilins) [Intracellular trafficking and secretion]; Region: VirB2; COG3838
1105113000848	MJ0042 family finger-like domain; Region: MJ0042_CXXC; TIGR02098
1105113000849	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1105113000850	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1105113000851	trimer interface [polypeptide binding]; other site
1105113000852	active site
1105113000853	substrate binding site [chemical binding]; other site
1105113000854	CoA binding site [chemical binding]; other site
1105113000855	potential frameshift: common BLAST hit: gi|157964260|ref|YP_001499084.1| bifunctional penicillin-binding protein 1C
1105113000856	potential frameshift: common BLAST hit: gi|157828131|ref|YP_001494373.1| cell surface antigen-like protein Sca8
1105113000857	potential frameshift: common BLAST hit: gi|157828132|ref|YP_001494374.1| cell surface antigen-like protein Sca8
1105113000858	potential frameshift: common BLAST hit: gi|67459460|ref|YP_247084.1| cell surface antigen-like protein Sca8
1105113000859	potential frameshift: common BLAST hit: gi|341583486|ref|YP_004763977.1| cell surface antigen-like protein Sca8
1105113000860	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1105113000861	Ligand Binding Site [chemical binding]; other site
1105113000862	TRAP-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: Imp; COG2358
1105113000863	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
1105113000864	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1105113000865	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1105113000866	catalytic loop [active]
1105113000867	iron binding site [ion binding]; other site
1105113000868	chaperone protein HscA; Provisional; Region: hscA; PRK01433
1105113000869	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1105113000870	nucleotide binding site [chemical binding]; other site
1105113000871	co-chaperone HscB; Provisional; Region: hscB; PRK01356
1105113000872	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1105113000873	HSP70 interaction site [polypeptide binding]; other site
1105113000874	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1105113000875	RNA/DNA hybrid binding site [nucleotide binding]; other site
1105113000876	active site
1105113000877	excinuclease ABC subunit B; Provisional; Region: PRK05298
1105113000878	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105113000879	ATP binding site [chemical binding]; other site
1105113000880	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105113000881	nucleotide binding region [chemical binding]; other site
1105113000882	ATP-binding site [chemical binding]; other site
1105113000883	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1105113000884	UvrB/uvrC motif; Region: UVR; pfam02151
1105113000885	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1105113000886	GSH binding site [chemical binding]; other site
1105113000887	catalytic residues [active]
1105113000888	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
1105113000889	potential frameshift: common BLAST hit: gi|157964270|ref|YP_001499094.1| multidrug resistance protein Atm1
1105113000890	potential frameshift: common BLAST hit: gi|157964270|ref|YP_001499094.1| multidrug resistance protein Atm1
1105113000891	potential frameshift: common BLAST hit: gi|341583496|ref|YP_004763987.1| multidrug resistance protein Atm1
1105113000892	DNA gyrase subunit A; Validated; Region: PRK05560
1105113000893	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1105113000894	CAP-like domain; other site
1105113000895	active site
1105113000896	primary dimer interface [polypeptide binding]; other site
1105113000897	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105113000898	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105113000899	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105113000900	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105113000901	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1105113000902	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1105113000903	Iron-sulphur cluster assembly; Region: Fe-S_assembly; pfam04384
1105113000904	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1105113000905	active site
1105113000906	catalytic residues [active]
1105113000907	metal binding site [ion binding]; metal-binding site
1105113000908	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1105113000909	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1105113000910	putative active site [active]
1105113000911	substrate binding site [chemical binding]; other site
1105113000912	putative cosubstrate binding site; other site
1105113000913	catalytic site [active]
1105113000914	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1105113000915	substrate binding site [chemical binding]; other site
1105113000916	potential frameshift: common BLAST hit: gi|374319001|ref|YP_005065499.1| capsular polysaccharide biosynthesis protein
1105113000917	Predicted ATPase [General function prediction only]; Region: COG1485
1105113000918	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113000919	Walker A motif; other site
1105113000920	ATP binding site [chemical binding]; other site
1105113000921	Walker B motif; other site
1105113000922	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: PRK01424
1105113000923	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1105113000924	potential frameshift: common BLAST hit: gi|350273268|ref|YP_004884581.1| ankyrin
1105113000925	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1105113000926	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105113000927	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113000928	Walker A/P-loop; other site
1105113000929	ATP binding site [chemical binding]; other site
1105113000930	Q-loop/lid; other site
1105113000931	ABC transporter signature motif; other site
1105113000932	Walker B; other site
1105113000933	D-loop; other site
1105113000934	H-loop/switch region; other site
1105113000935	Protein of unknown function (DUF2671); Region: DUF2671; pfam10877
1105113000936	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1105113000937	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1105113000938	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1105113000939	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
1105113000940	toxin-antitoxin system, toxin component, Txe/YoeB family; Region: toxin_Txe_YoeB; TIGR02116
1105113000941	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1105113000942	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1105113000943	putative metal binding site; other site
1105113000944	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1105113000945	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1105113000946	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1105113000947	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1105113000948	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1105113000949	ATP binding site [chemical binding]; other site
1105113000950	active site
1105113000951	substrate binding site [chemical binding]; other site
1105113000952	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1105113000953	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1105113000954	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1105113000955	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1105113000956	active site
1105113000957	dimer interface [polypeptide binding]; other site
1105113000958	motif 1; other site
1105113000959	motif 2; other site
1105113000960	motif 3; other site
1105113000961	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1105113000962	anticodon binding site; other site
1105113000963	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113000964	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113000965	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1105113000966	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113000967	Walker A/P-loop; other site
1105113000968	ATP binding site [chemical binding]; other site
1105113000969	Q-loop/lid; other site
1105113000970	ABC transporter signature motif; other site
1105113000971	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113000972	H-loop/switch region; other site
1105113000973	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310); Region: DUF2310; cl02380
1105113000974	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310); Region: DUF2310; cl02380
1105113000975	Protein of unknown function (DUF2660); Region: DUF2660; pfam10859
1105113000976	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1105113000977	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3827
1105113000978	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105113000979	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
1105113000980	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1105113000981	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105113000982	ATP binding site [chemical binding]; other site
1105113000983	Mg2+ binding site [ion binding]; other site
1105113000984	G-X-G motif; other site
1105113000985	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1105113000986	anchoring element; other site
1105113000987	dimer interface [polypeptide binding]; other site
1105113000988	ATP binding site [chemical binding]; other site
1105113000989	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1105113000990	active site
1105113000991	metal binding site [ion binding]; metal-binding site
1105113000992	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1105113000993	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1105113000994	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1105113000995	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1105113000996	protein binding site [polypeptide binding]; other site
1105113000997	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1105113000998	Catalytic dyad [active]
1105113000999	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1105113001000	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105113001001	dimer interface [polypeptide binding]; other site
1105113001002	phosphorylation site [posttranslational modification]
1105113001003	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105113001004	ATP binding site [chemical binding]; other site
1105113001005	Mg2+ binding site [ion binding]; other site
1105113001006	G-X-G motif; other site
1105113001007	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1105113001008	Protein of unknown function (DUF2659); Region: DUF2659; pfam10858
1105113001009	FOG: WD40-like repeat [Function unknown]; Region: COG1520
1105113001010	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1105113001011	Trp docking motif [polypeptide binding]; other site
1105113001012	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1105113001013	23S rRNA interface [nucleotide binding]; other site
1105113001014	L3 interface [polypeptide binding]; other site
1105113001015	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1105113001016	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
1105113001017	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
1105113001018	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH_subfamily_a; cd00913
1105113001019	aromatic arch; other site
1105113001020	DCoH dimer interaction site [polypeptide binding]; other site
1105113001021	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
1105113001022	DCoH tetramer interaction site [polypeptide binding]; other site
1105113001023	substrate binding site [chemical binding]; other site
1105113001024	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1105113001025	putative active site [active]
1105113001026	Ap4A binding site [chemical binding]; other site
1105113001027	nudix motif; other site
1105113001028	putative metal binding site [ion binding]; other site
1105113001029	response regulator PleD; Reviewed; Region: pleD; PRK09581
1105113001030	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105113001031	active site
1105113001032	phosphorylation site [posttranslational modification]
1105113001033	intermolecular recognition site; other site
1105113001034	dimerization interface [polypeptide binding]; other site
1105113001035	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105113001036	active site
1105113001037	phosphorylation site [posttranslational modification]
1105113001038	intermolecular recognition site; other site
1105113001039	dimerization interface [polypeptide binding]; other site
1105113001040	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1105113001041	metal binding site [ion binding]; metal-binding site
1105113001042	active site
1105113001043	I-site; other site
1105113001044	elongation factor P; Validated; Region: PRK00529
1105113001045	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1105113001046	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1105113001047	RNA binding site [nucleotide binding]; other site
1105113001048	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1105113001049	RNA binding site [nucleotide binding]; other site
1105113001050	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1105113001051	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
1105113001052	active site
1105113001053	Domain of unknown function (DUF2610); Region: DUF2610; pfam11020
1105113001054	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
1105113001055	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1105113001056	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1105113001057	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
1105113001058	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1105113001059	HlyD family secretion protein; Region: HlyD_3; pfam13437
1105113001060	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105113001061	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
1105113001062	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1105113001063	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1105113001064	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1105113001065	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105113001066	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105113001067	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1105113001068	FAD binding domain; Region: FAD_binding_4; pfam01565
1105113001069	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1105113001070	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1105113001071	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1105113001072	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1105113001073	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
1105113001074	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1105113001075	Cell division protein FtsQ; Region: FtsQ; pfam03799
1105113001076	cell division protein FtsA; Region: ftsA; TIGR01174
1105113001077	Cell division protein FtsA; Region: FtsA; smart00842
1105113001078	Cell division protein FtsA; Region: FtsA; pfam14450
1105113001079	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1105113001080	Cytochrome c2 [Energy production and conversion]; Region: COG3474
1105113001081	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1105113001082	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1105113001083	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105113001084	RNA binding site [nucleotide binding]; other site
1105113001085	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105113001086	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
1105113001087	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
1105113001088	Cytochrome oxidase assembly protein; Region: COX15-CtaA; cl15852
1105113001089	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1105113001090	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105113001091	RNA binding surface [nucleotide binding]; other site
1105113001092	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1105113001093	active site
1105113001094	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1105113001095	Beta-lactamase; Region: Beta-lactamase; pfam00144
1105113001096	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1105113001097	putative catalytic site [active]
1105113001098	putative phosphate binding site [ion binding]; other site
1105113001099	active site
1105113001100	metal binding site A [ion binding]; metal-binding site
1105113001101	DNA binding site [nucleotide binding]
1105113001102	putative AP binding site [nucleotide binding]; other site
1105113001103	putative metal binding site B [ion binding]; other site
1105113001104	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
1105113001105	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1105113001106	tetramer interface [polypeptide binding]; other site
1105113001107	TPP-binding site [chemical binding]; other site
1105113001108	heterodimer interface [polypeptide binding]; other site
1105113001109	phosphorylation loop region [posttranslational modification]
1105113001110	pyruvate dehydrogenase subunit beta; Validated; Region: PRK09212
1105113001111	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1105113001112	alpha subunit interface [polypeptide binding]; other site
1105113001113	TPP binding site [chemical binding]; other site
1105113001114	heterodimer interface [polypeptide binding]; other site
1105113001115	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1105113001116	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1105113001117	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1105113001118	G1 box; other site
1105113001119	putative GEF interaction site [polypeptide binding]; other site
1105113001120	GTP/Mg2+ binding site [chemical binding]; other site
1105113001121	Switch I region; other site
1105113001122	G2 box; other site
1105113001123	G3 box; other site
1105113001124	Switch II region; other site
1105113001125	G4 box; other site
1105113001126	G5 box; other site
1105113001127	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1105113001128	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1105113001129	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: HlpA; COG2825
1105113001130	isocitrate dehydrogenase; Validated; Region: PRK09222
1105113001131	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
1105113001132	monovalent cation/proton antiporter, MnhG/PhaG subunit; Region: CPA3_mnhG_phaG; TIGR01300
1105113001133	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12507
1105113001134	Predicted subunit of the Multisubunit Na+/H+ antiporter [Inorganic ion transport and metabolism]; Region: COG1563
1105113001135	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
1105113001136	Protein of unknown function (DUF2670); Region: DUF2670; pfam10875
1105113001137	Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal; Region: UCR_Fe-S_N; pfam10399
1105113001138	ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416
1105113001139	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
1105113001140	[2Fe-2S] cluster binding site [ion binding]; other site
1105113001141	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
1105113001142	Qi binding site; other site
1105113001143	cytochrome b; Provisional; Region: CYTB; MTH00191
1105113001144	intrachain domain interface; other site
1105113001145	interchain domain interface [polypeptide binding]; other site
1105113001146	heme bH binding site [chemical binding]; other site
1105113001147	heme bL binding site [chemical binding]; other site
1105113001148	Qo binding site; other site
1105113001149	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cd00290
1105113001150	interchain domain interface [polypeptide binding]; other site
1105113001151	intrachain domain interface; other site
1105113001152	Qi binding site; other site
1105113001153	Qo binding site; other site
1105113001154	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
1105113001155	catalytic site [active]
1105113001156	metal binding site [ion binding]; metal-binding site
1105113001157	Cytochrome C1 family; Region: Cytochrom_C1; pfam02167
1105113001158	Cytochrome c; Region: Cytochrom_C; cl11414
1105113001159	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1105113001160	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
1105113001161	putative dimer interface [polypeptide binding]; other site
1105113001162	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1105113001163	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1105113001164	PCRF domain; Region: PCRF; pfam03462
1105113001165	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1105113001166	RF-1 domain; Region: RF-1; pfam00472
1105113001167	GTP-binding protein LepA; Provisional; Region: PRK05433
1105113001168	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1105113001169	G1 box; other site
1105113001170	putative GEF interaction site [polypeptide binding]; other site
1105113001171	GTP/Mg2+ binding site [chemical binding]; other site
1105113001172	Switch I region; other site
1105113001173	G2 box; other site
1105113001174	G3 box; other site
1105113001175	Switch II region; other site
1105113001176	G4 box; other site
1105113001177	G5 box; other site
1105113001178	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1105113001179	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1105113001180	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1105113001181	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1105113001182	Autotransporter beta-domain; Region: Autotransporter; smart00869
1105113001183	potential frameshift: common BLAST hit: gi|165933830|ref|YP_001650619.1| outer membrane protein A
1105113001184	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1105113001185	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1105113001186	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1105113001187	potential frameshift: common BLAST hit: gi|67458839|ref|YP_246463.1| NACHT domain-containing protein
1105113001188	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105113001189	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1105113001190	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
1105113001191	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105113001192	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1105113001193	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK06588
1105113001194	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105113001195	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
1105113001196	oligomeric interface; other site
1105113001197	putative active site [active]
1105113001198	homodimer interface [polypeptide binding]; other site
1105113001199	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK06589
1105113001200	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105113001201	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK06591
1105113001202	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105113001203	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK07375
1105113001204	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
1105113001205	VirB7 interaction site; other site
1105113001206	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1105113001207	Protein of unknown function (DUF2706); Region: DUF2706; pfam10913
1105113001208	Type IV secretory pathway, component VirB8 [Intracellular trafficking and secretion]; Region: VirB8; COG3736
1105113001209	Type IV secretory pathway, VirB9 components [Intracellular trafficking and secretion]; Region: VirB9; COG3504
1105113001210	Type IV secretory pathway, VirB10 components [Intracellular trafficking and secretion]; Region: VirB10; COG2948
1105113001211	type IV secretion system ATPase VirB11; Provisional; Region: PRK13900
1105113001212	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
1105113001213	Walker A motif; other site
1105113001214	hexamer interface [polypeptide binding]; other site
1105113001215	ATP binding site [chemical binding]; other site
1105113001216	Walker B motif; other site
1105113001217	type IV secretion system component VirD4; Provisional; Region: PRK13897
1105113001218	The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion. These proteins aid the transfer of DNA from the plasmid into the host bacterial chromosome. They contain an ATP binding domain. VirD4 is involved in DNA transfer...; Region: TraG_VirD4; cd01126
1105113001219	Walker A motif; other site
1105113001220	ATP binding site [chemical binding]; other site
1105113001221	Walker B motif; other site
1105113001222	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
1105113001223	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1105113001224	Phage-related protein [Function unknown]; Region: COG4695; cl01923
1105113001225	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105113001226	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105113001227	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1105113001228	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1105113001229	active site
1105113001230	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1105113001231	MutS domain I; Region: MutS_I; pfam01624
1105113001232	MutS domain II; Region: MutS_II; pfam05188
1105113001233	MutS domain III; Region: MutS_III; pfam05192
1105113001234	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1105113001235	Walker A/P-loop; other site
1105113001236	ATP binding site [chemical binding]; other site
1105113001237	Q-loop/lid; other site
1105113001238	ABC transporter signature motif; other site
1105113001239	Walker B; other site
1105113001240	D-loop; other site
1105113001241	H-loop/switch region; other site
1105113001242	Ribose/Galactose Isomerase; Region: LacAB_rpiB; cl00485
1105113001243	Peptidase family M23; Region: Peptidase_M23; pfam01551
1105113001244	Protein of unknown function DUF45; Region: DUF45; pfam01863
1105113001245	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
1105113001246	translocation protein TolB; Provisional; Region: tolB; PRK05137
1105113001247	TolB amino-terminal domain; Region: TolB_N; pfam04052
1105113001248	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1105113001249	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1105113001250	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1105113001251	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1105113001252	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1105113001253	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1105113001254	DNA binding residues [nucleotide binding]
1105113001255	Cytochrome oxidase assembly factor [Posttranslational modification, protein turnover, chaperones]; Region: COX11; COG3175
1105113001256	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1105113001257	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1105113001258	Ligand Binding Site [chemical binding]; other site
1105113001259	amino acid transporter; Region: 2A0306; TIGR00909
1105113001260	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1105113001261	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1105113001262	dimer interface [polypeptide binding]; other site
1105113001263	motif 1; other site
1105113001264	active site
1105113001265	motif 2; other site
1105113001266	motif 3; other site
1105113001267	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1105113001268	anticodon binding site; other site
1105113001269	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1105113001270	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113001271	Walker A/P-loop; other site
1105113001272	ATP binding site [chemical binding]; other site
1105113001273	Q-loop/lid; other site
1105113001274	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105113001275	TolQ protein; Region: tolQ; TIGR02796
1105113001276	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1105113001277	TolR protein; Region: tolR; TIGR02801
1105113001278	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113001279	HD domain; Region: HD_4; pfam13328
1105113001280	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105113001281	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105113001282	putative substrate translocation pore; other site
1105113001283	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1105113001284	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
1105113001285	HlyD family secretion protein; Region: HlyD_3; pfam13437
1105113001286	type I secretion system ABC transporter, PrtD family; Region: type_I_sec_PrtD; TIGR01842
1105113001287	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105113001288	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
1105113001289	Walker A/P-loop; other site
1105113001290	ATP binding site [chemical binding]; other site
1105113001291	Q-loop/lid; other site
1105113001292	ABC transporter signature motif; other site
1105113001293	Walker B; other site
1105113001294	D-loop; other site
1105113001295	H-loop/switch region; other site
1105113001296	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1105113001297	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1105113001298	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
1105113001299	nucleotide binding site/active site [active]
1105113001300	HIT family signature motif; other site
1105113001301	catalytic residue [active]
1105113001302	UDP-glucosyl transferase; Region: PLN02210
1105113001303	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
1105113001304	Rickettsial palindromic element RPE5 domain; Region: RPE5; TIGR03776
1105113001305	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1105113001306	active site
1105113001307	HslU subunit interaction site [polypeptide binding]; other site
1105113001308	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1105113001309	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113001310	Walker A motif; other site
1105113001311	ATP binding site [chemical binding]; other site
1105113001312	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1105113001313	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1105113001314	potential frameshift: common BLAST hit: gi|91205630|ref|YP_537985.1| Mg chelatase-like protein
1105113001315	potential frameshift: common BLAST hit: gi|157827341|ref|YP_001496405.1| Mg chelatase-like protein
1105113001316	potential frameshift: common BLAST hit: gi|67458910|ref|YP_246534.1| Mg chelatase-like protein
1105113001317	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105113001318	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1105113001319	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1105113001320	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105113001321	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
1105113001322	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1105113001323	dimerization interface [polypeptide binding]; other site
1105113001324	frataxin-like protein; Provisional; Region: cyaY; PRK01379
1105113001325	putative iron binding site [ion binding]; other site
1105113001326	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
1105113001327	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
1105113001328	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1105113001329	glutamyl-tRNA synthetase; Provisional; Region: PRK12558
1105113001330	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105113001331	HIGH motif; other site
1105113001332	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105113001333	active site
1105113001334	KMSKS motif; other site
1105113001335	DNA topoisomerase I; Validated; Region: PRK06599
1105113001336	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1105113001337	active site
1105113001338	interdomain interaction site; other site
1105113001339	putative metal-binding site [ion binding]; other site
1105113001340	nucleotide binding site [chemical binding]; other site
1105113001341	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1105113001342	domain I; other site
1105113001343	DNA binding groove [nucleotide binding]
1105113001344	phosphate binding site [ion binding]; other site
1105113001345	domain II; other site
1105113001346	domain III; other site
1105113001347	nucleotide binding site [chemical binding]; other site
1105113001348	catalytic site [active]
1105113001349	domain IV; other site
1105113001350	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1105113001351	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1105113001352	DNA protecting protein DprA; Region: dprA; TIGR00732
1105113001353	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1105113001354	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1105113001355	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1105113001356	dimer interface [polypeptide binding]; other site
1105113001357	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1105113001358	catalytic triad [active]
1105113001359	peroxidatic and resolving cysteines [active]
1105113001360	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1105113001361	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1105113001362	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1105113001363	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1105113001364	Sulfatase; Region: Sulfatase; pfam00884
1105113001365	Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair]; Region: COG0816
1105113001366	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
1105113001367	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105113001368	non-specific DNA binding site [nucleotide binding]; other site
1105113001369	salt bridge; other site
1105113001370	sequence-specific DNA binding site [nucleotide binding]; other site
1105113001371	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
1105113001372	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1105113001373	NADP binding site [chemical binding]; other site
1105113001374	active site
1105113001375	putative substrate binding site [chemical binding]; other site
1105113001376	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
1105113001377	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1105113001378	NAD(P) binding site [chemical binding]; other site
1105113001379	homodimer interface [polypeptide binding]; other site
1105113001380	substrate binding site [chemical binding]; other site
1105113001381	active site
1105113001382	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
1105113001383	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1105113001384	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1105113001385	active site
1105113001386	homodimer interface [polypeptide binding]; other site
1105113001387	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105113001388	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113001389	S-adenosylmethionine binding site [chemical binding]; other site
1105113001390	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105113001391	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1105113001392	active site
1105113001393	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105113001394	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1105113001395	active site
1105113001396	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
1105113001397	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1105113001398	HlyD family secretion protein; Region: HlyD_3; pfam13437
1105113001399	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
1105113001400	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1105113001401	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1105113001402	catalytic site [active]
1105113001403	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1105113001404	This family is most closely related to the GT1 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core; Region: GT1_WavL_like; cd03819
1105113001405	putative ADP-binding pocket [chemical binding]; other site
1105113001406	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1105113001407	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1105113001408	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105113001409	RNA binding surface [nucleotide binding]; other site
1105113001410	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
1105113001411	UbiA prenyltransferase family; Region: UbiA; pfam01040
1105113001412	spore photoproduct lyase; Region: photo_TT_lyase; cl15393
1105113001413	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1105113001414	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1105113001415	TPR motif; other site
1105113001416	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1105113001417	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1105113001418	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1105113001419	RimM N-terminal domain; Region: RimM; pfam01782
1105113001420	PRC-barrel domain; Region: PRC; pfam05239
1105113001421	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1105113001422	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1105113001423	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
1105113001424	active site
1105113001425	DNA binding site [nucleotide binding]
1105113001426	hypothetical protein; Provisional; Region: PRK14388
1105113001427	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1105113001428	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1105113001429	putative dimer interface [polypeptide binding]; other site
1105113001430	[2Fe-2S] cluster binding site [ion binding]; other site
1105113001431	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
1105113001432	GIY-YIG motif/motif A; other site
1105113001433	putative active site [active]
1105113001434	putative metal binding site [ion binding]; other site
1105113001435	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
1105113001436	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1105113001437	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
1105113001438	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1105113001439	NADH dehydrogenase subunit B; Validated; Region: PRK06411
1105113001440	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1105113001441	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1105113001442	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4765
1105113001443	potential frameshift: common BLAST hit: gi|67458962|ref|YP_246586.1| phage protein
1105113001444	potential frameshift: common BLAST hit: gi|67458962|ref|YP_246586.1| phage protein
1105113001445	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1105113001446	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1105113001447	active site
1105113001448	DNA binding site [nucleotide binding]
1105113001449	Int/Topo IB signature motif; other site
1105113001450	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06603
1105113001451	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1105113001452	NAD binding site [chemical binding]; other site
1105113001453	homotetramer interface [polypeptide binding]; other site
1105113001454	homodimer interface [polypeptide binding]; other site
1105113001455	substrate binding site [chemical binding]; other site
1105113001456	active site
1105113001457	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1105113001458	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1105113001459	putative active site [active]
1105113001460	catalytic triad [active]
1105113001461	putative dimer interface [polypeptide binding]; other site
1105113001462	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1105113001463	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1105113001464	amidase catalytic site [active]
1105113001465	Zn binding residues [ion binding]; other site
1105113001466	substrate binding site [chemical binding]; other site
1105113001467	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1105113001468	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG2984
1105113001469	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1105113001470	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
1105113001471	TM-ABC transporter signature motif; other site
1105113001472	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
1105113001473	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113001474	Walker A/P-loop; other site
1105113001475	ATP binding site [chemical binding]; other site
1105113001476	Q-loop/lid; other site
1105113001477	ABC transporter signature motif; other site
1105113001478	Walker B; other site
1105113001479	D-loop; other site
1105113001480	H-loop/switch region; other site
1105113001481	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105113001482	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105113001483	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105113001484	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1105113001485	lysyl-tRNA synthetase; Reviewed; Region: lysK; PRK00750
1105113001486	catalytic core domain of  class I lysyl tRNA synthetase; Region: LysRS_core_class_I; cd00674
1105113001487	active site
1105113001488	HIGH motif; other site
1105113001489	KMSKS motif; other site
1105113001490	Predicted permeases [General function prediction only]; Region: COG0679
1105113001491	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1105113001492	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1105113001493	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1105113001494	putative NAD(P) binding site [chemical binding]; other site
1105113001495	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1105113001496	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
1105113001497	putative active site [active]
1105113001498	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
1105113001499	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105113001500	DNA polymerase III, alpha subunit (gram-positive type) [DNA replication, recombination, and repair]; Region: PolC; COG2176
1105113001501	malate dehydrogenase; Reviewed; Region: PRK06223
1105113001502	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
1105113001503	NAD(P) binding site [chemical binding]; other site
1105113001504	dimer interface [polypeptide binding]; other site
1105113001505	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1105113001506	substrate binding site [chemical binding]; other site
1105113001507	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105113001508	potential frameshift: common BLAST hit: gi|157964457|ref|YP_001499281.1| CTP synthetase
1105113001509	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1105113001510	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1105113001511	Ligand binding site; other site
1105113001512	oligomer interface; other site
1105113001513	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1105113001514	nudix motif; other site
1105113001515	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
1105113001516	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
1105113001517	GTP cyclohydrolase I; Provisional; Region: PLN03044
1105113001518	active site
1105113001519	prolyl-tRNA synthetase; Provisional; Region: PRK12325
1105113001520	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1105113001521	dimer interface [polypeptide binding]; other site
1105113001522	motif 1; other site
1105113001523	active site
1105113001524	motif 2; other site
1105113001525	motif 3; other site
1105113001526	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1105113001527	anticodon binding site; other site
1105113001528	Fic family protein [Function unknown]; Region: COG3177
1105113001529	Fic/DOC family; Region: Fic; pfam02661
1105113001530	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1105113001531	RuvA N terminal domain; Region: RuvA_N; pfam01330
1105113001532	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1105113001533	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1105113001534	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113001535	Walker A motif; other site
1105113001536	ATP binding site [chemical binding]; other site
1105113001537	Walker B motif; other site
1105113001538	arginine finger; other site
1105113001539	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1105113001540	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1105113001541	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105113001542	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113001543	Walker A/P-loop; other site
1105113001544	ATP binding site [chemical binding]; other site
1105113001545	Q-loop/lid; other site
1105113001546	ABC transporter signature motif; other site
1105113001547	Walker B; other site
1105113001548	D-loop; other site
1105113001549	H-loop/switch region; other site
1105113001550	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1105113001551	muropeptide transporter; Validated; Region: ampG; cl17669
1105113001552	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1105113001553	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1105113001554	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113001555	Rickettsial palindromic element RPE5 domain; Region: RPE5; TIGR03776
1105113001556	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1105113001557	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1105113001558	Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823
1105113001559	BON domain; Region: BON; pfam04972
1105113001560	BON domain; Region: BON; pfam04972
1105113001561	Intracellular septation protein A [Cell division and chromosome partitioning]; Region: COG2917
1105113001562	Iron permease FTR1 family; Region: FTR1; cl00475
1105113001563	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
1105113001564	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1105113001565	Protocatechuate 3,4-dioxygenase beta subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PcaH; COG3485
1105113001566	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
1105113001567	active site
1105113001568	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1105113001569	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1105113001570	catalytic residues [active]
1105113001571	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
1105113001572	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1105113001573	tandem repeat interface [polypeptide binding]; other site
1105113001574	oligomer interface [polypeptide binding]; other site
1105113001575	active site residues [active]
1105113001576	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1105113001577	trimer interface [polypeptide binding]; other site
1105113001578	active site
1105113001579	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1105113001580	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1105113001581	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1105113001582	catalytic residue [active]
1105113001583	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1105113001584	dimer interface [polypeptide binding]; other site
1105113001585	catalytic triad [active]
1105113001586	Rickettsial palindromic element RPE4 domain; Region: RPE4; TIGR03777
1105113001587	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
1105113001588	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1105113001589	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1105113001590	catalytic triad [active]
1105113001591	cytochrome c oxidase subunit I; Validated; Region: COX1; MTH00007
1105113001592	Cytochrome C oxidase subunit I.  Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663
1105113001593	Subunit I/III interface [polypeptide binding]; other site
1105113001594	D-pathway; other site
1105113001595	Subunit I/VIIc interface [polypeptide binding]; other site
1105113001596	Subunit I/IV interface [polypeptide binding]; other site
1105113001597	Subunit I/II interface [polypeptide binding]; other site
1105113001598	Low-spin heme (heme a) binding site [chemical binding]; other site
1105113001599	Subunit I/VIIa interface [polypeptide binding]; other site
1105113001600	Subunit I/VIa interface [polypeptide binding]; other site
1105113001601	Dimer interface; other site
1105113001602	Putative water exit pathway; other site
1105113001603	Binuclear center (heme a3/CuB) [ion binding]; other site
1105113001604	K-pathway; other site
1105113001605	Subunit I/Vb interface [polypeptide binding]; other site
1105113001606	Putative proton exit pathway; other site
1105113001607	Subunit I/VIb interface; other site
1105113001608	Subunit I/VIc interface [polypeptide binding]; other site
1105113001609	Electron transfer pathway; other site
1105113001610	Subunit I/VIIIb interface [polypeptide binding]; other site
1105113001611	Subunit I/VIIb interface [polypeptide binding]; other site
1105113001612	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1105113001613	CoA binding site [chemical binding]; other site
1105113001614	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113001615	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
1105113001616	cytochrome c oxidase subunit II; Provisional; Region: COX2; MTH00154
1105113001617	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1105113001618	Cytidylyltransferase [Cell envelope biogenesis, outer membrane / Lipid metabolism]; Region: TagD; COG0615
1105113001619	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1105113001620	active site
1105113001621	HIGH motif; other site
1105113001622	nucleotide binding site [chemical binding]; other site
1105113001623	putative peptidase; Provisional; Region: PRK11649
1105113001624	Peptidase family M23; Region: Peptidase_M23; pfam01551
1105113001625	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1105113001626	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1105113001627	Protein of unknown function (DUF3035); Region: DUF3035; pfam11233
1105113001628	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01368
1105113001629	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105113001630	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105113001631	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105113001632	cell division protein FtsW; Region: ftsW; TIGR02614
1105113001633	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1105113001634	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1105113001635	active site
1105113001636	homodimer interface [polypeptide binding]; other site
1105113001637	potential frameshift: common BLAST hit: gi|67459031|ref|YP_246655.1| RND family efflux transporter
1105113001638	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113001639	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113001640	potential frameshift: common BLAST hit: gi|157827177|ref|YP_001496241.1| RND family efflux transporter
1105113001641	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1105113001642	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1105113001643	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
1105113001644	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1105113001645	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1105113001646	potential frameshift: common BLAST hit: gi|374319263|ref|YP_005065762.1| Transposase-like protein
1105113001647	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105113001648	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105113001649	diaminopimelate epimerase; Region: DapF; TIGR00652
1105113001650	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1105113001651	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1105113001652	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1105113001653	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1105113001654	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105113001655	FeS/SAM binding site; other site
1105113001656	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1105113001657	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1105113001658	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1105113001659	dimer interface [polypeptide binding]; other site
1105113001660	motif 1; other site
1105113001661	active site
1105113001662	motif 2; other site
1105113001663	motif 3; other site
1105113001664	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1105113001665	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1105113001666	putative tRNA-binding site [nucleotide binding]; other site
1105113001667	B3/4 domain; Region: B3_4; pfam03483
1105113001668	tRNA synthetase B5 domain; Region: B5; smart00874
1105113001669	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1105113001670	dimer interface [polypeptide binding]; other site
1105113001671	motif 1; other site
1105113001672	motif 3; other site
1105113001673	motif 2; other site
1105113001674	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1105113001675	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1105113001676	DNA polymerase III subunit beta; Validated; Region: PRK05643
1105113001677	putative DNA binding surface [nucleotide binding]; other site
1105113001678	dimer interface [polypeptide binding]; other site
1105113001679	beta-clamp/clamp loader binding surface; other site
1105113001680	beta-clamp/translesion DNA polymerase binding surface; other site
1105113001681	Protein of unknown function (DUF1653); Region: DUF1653; cl01949
1105113001682	Domain of unknown function (DUF3576); Region: DUF3576; pfam12100
1105113001683	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1105113001684	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1105113001685	HIGH motif; other site
1105113001686	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1105113001687	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105113001688	active site
1105113001689	KMSKS motif; other site
1105113001690	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1105113001691	tRNA binding surface [nucleotide binding]; other site
1105113001692	Rickettsial palindromic element RPE5 domain; Region: RPE5; TIGR03776
1105113001693	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
1105113001694	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1105113001695	catalytic site [active]
1105113001696	putative active site [active]
1105113001697	putative substrate binding site [chemical binding]; other site
1105113001698	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1105113001699	Septum formation initiator; Region: DivIC; pfam04977
1105113001700	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1105113001701	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1105113001702	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1105113001703	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1105113001704	catalytic residue [active]
1105113001705	putative FPP diphosphate  binding site; other site
1105113001706	putative FPP binding hydrophobic cleft; other site
1105113001707	dimer interface [polypeptide binding]; other site
1105113001708	putative IPP diphosphate binding site; other site
1105113001709	Rickettsial palindromic element RPE3 domain; Region: RPE3; TIGR03775
1105113001710	HAMP domain; Region: HAMP; pfam00672
1105113001711	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105113001712	dimer interface [polypeptide binding]; other site
1105113001713	phosphorylation site [posttranslational modification]
1105113001714	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105113001715	ATP binding site [chemical binding]; other site
1105113001716	Mg2+ binding site [ion binding]; other site
1105113001717	G-X-G motif; other site
1105113001718	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1105113001719	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105113001720	active site
1105113001721	phosphorylation site [posttranslational modification]
1105113001722	intermolecular recognition site; other site
1105113001723	dimerization interface [polypeptide binding]; other site
1105113001724	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1105113001725	DNA binding site [nucleotide binding]
1105113001726	branched-chain amino acid aminotransferase; Validated; Region: PRK06606
1105113001727	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1105113001728	homodimer interface [polypeptide binding]; other site
1105113001729	substrate-cofactor binding pocket; other site
1105113001730	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105113001731	catalytic residue [active]
1105113001732	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1105113001733	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1105113001734	dimer interface [polypeptide binding]; other site
1105113001735	active site
1105113001736	catalytic residue [active]
1105113001737	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1105113001738	SmpB-tmRNA interface; other site
1105113001739	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1105113001740	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1105113001741	catalytic residues [active]
1105113001742	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1105113001743	CoA binding domain; Region: CoA_binding; pfam02629
1105113001744	CoA-ligase; Region: Ligase_CoA; pfam00549
1105113001745	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1105113001746	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1105113001747	CoA-ligase; Region: Ligase_CoA; pfam00549
1105113001748	potential frameshift: common BLAST hit: gi|374319289|ref|YP_005065788.1| Putative nucleic-acid-binding protein, containing PIN domain
1105113001749	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1105113001750	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
1105113001751	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
1105113001752	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1105113001753	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4395
1105113001754	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1105113001755	Predicted membrane protein [Function unknown]; Region: COG1238
1105113001756	Predicted membrane protein/domain [Function unknown]; Region: COG1714
1105113001757	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
1105113001758	RecR protein; Region: RecR; pfam02132
1105113001759	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1105113001760	putative active site [active]
1105113001761	putative metal-binding site [ion binding]; other site
1105113001762	tetramer interface [polypeptide binding]; other site
1105113001763	inorganic polyphosphate/ATP-NAD kinase; Reviewed; Region: ppnK; PRK04761
1105113001764	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1105113001765	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1105113001766	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1105113001767	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1105113001768	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1105113001769	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1105113001770	Predicted permeases [General function prediction only]; Region: COG0679
1105113001771	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1105113001772	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1105113001773	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1105113001774	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105113001775	potential frameshift: common BLAST hit: gi|157964531|ref|YP_001499355.1| succinate semialdehyde dehydrogenase
1105113001776	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1105113001777	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1105113001778	active site
1105113001779	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1105113001780	Part of AAA domain; Region: AAA_19; pfam13245
1105113001781	Family description; Region: UvrD_C_2; pfam13538
1105113001782	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1105113001783	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1105113001784	tetramer interface [polypeptide binding]; other site
1105113001785	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1105113001786	catalytic residue [active]
1105113001787	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1105113001788	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1105113001789	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113001790	Walker A motif; other site
1105113001791	ATP binding site [chemical binding]; other site
1105113001792	Walker B motif; other site
1105113001793	arginine finger; other site
1105113001794	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1105113001795	potential frameshift: common BLAST hit: gi|67459085|ref|YP_246709.1| cell surface antigen Sca3
1105113001796	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1105113001797	30S subunit binding site; other site
1105113001798	potential frameshift: common BLAST hit: gi|374319316|ref|YP_005065815.1| Carbonic anhydrase/acetyltransferase, isoleucine patch
1105113001799	potential frameshift: common BLAST hit: gi|229586740|ref|YP_002845241.1| Carbonic anhydrases/acetyltransferase, isoleucine patch superfamily
1105113001800	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14171
1105113001801	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1105113001802	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1105113001803	homodimer interface [polypeptide binding]; other site
1105113001804	NADP binding site [chemical binding]; other site
1105113001805	substrate binding site [chemical binding]; other site
1105113001806	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1105113001807	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1105113001808	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105113001809	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
1105113001810	potential frameshift: common BLAST hit: gi|165933233|ref|YP_001650022.1| protein U
1105113001811	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
1105113001812	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1105113001813	potential frameshift: common BLAST hit: gi|67459097|ref|YP_246721.1| P pilus assembly protein FimD
1105113001814	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1105113001815	Spore Coat Protein U domain; Region: SCPU; smart00972
1105113001816	Chitin binding domain; Region: Chitin_bind_3; cl03871
1105113001817	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113001818	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113001819	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
1105113001820	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1105113001821	active site
1105113001822	dimer interface [polypeptide binding]; other site
1105113001823	catalytic residues [active]
1105113001824	effector binding site; other site
1105113001825	R2 peptide binding site; other site
1105113001826	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1105113001827	dimer interface [polypeptide binding]; other site
1105113001828	putative radical transfer pathway; other site
1105113001829	diiron center [ion binding]; other site
1105113001830	tyrosyl radical; other site
1105113001831	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1105113001832	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1105113001833	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1105113001834	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1105113001835	active site
1105113001836	substrate binding site [chemical binding]; other site
1105113001837	metal binding site [ion binding]; metal-binding site
1105113001838	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1105113001839	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1105113001840	Walker A/P-loop; other site
1105113001841	ATP binding site [chemical binding]; other site
1105113001842	Q-loop/lid; other site
1105113001843	ABC transporter signature motif; other site
1105113001844	Walker B; other site
1105113001845	D-loop; other site
1105113001846	H-loop/switch region; other site
1105113001847	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113001848	OstA-like protein; Region: OstA; cl00844
1105113001849	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5375
1105113001850	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1105113001851	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1105113001852	putative active site [active]
1105113001853	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1105113001854	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1105113001855	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1105113001856	RNase E interface [polypeptide binding]; other site
1105113001857	trimer interface [polypeptide binding]; other site
1105113001858	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1105113001859	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1105113001860	RNase E interface [polypeptide binding]; other site
1105113001861	trimer interface [polypeptide binding]; other site
1105113001862	active site
1105113001863	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1105113001864	putative nucleic acid binding region [nucleotide binding]; other site
1105113001865	G-X-X-G motif; other site
1105113001866	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1105113001867	RNA binding site [nucleotide binding]; other site
1105113001868	domain interface; other site
1105113001869	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1105113001870	16S/18S rRNA binding site [nucleotide binding]; other site
1105113001871	S13e-L30e interaction site [polypeptide binding]; other site
1105113001872	25S rRNA binding site [nucleotide binding]; other site
1105113001873	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK14846
1105113001874	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1105113001875	RNA binding site [nucleotide binding]; other site
1105113001876	active site
1105113001877	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113001878	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105113001879	120 KDa Rickettsia surface antigen; Region: 120_Rick_ant; pfam12574
1105113001880	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1105113001881	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105113001882	non-specific DNA binding site [nucleotide binding]; other site
1105113001883	salt bridge; other site
1105113001884	sequence-specific DNA binding site [nucleotide binding]; other site
1105113001885	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
1105113001886	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1105113001887	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1105113001888	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1105113001889	uncharacterized protein, YfiH family; Region: TIGR00726
1105113001890	potential frameshift: common BLAST hit: gi|229586763|ref|YP_002845264.1| Polypeptide deformylase
1105113001891	potential frameshift: common BLAST hit: gi|374319342|ref|YP_005065841.1| Toxin of toxin-antitoxin (TA) system, containing PIN domain for
1105113001892	hypothetical protein; Provisional; Region: PRK06661
1105113001893	intersubunit interface [polypeptide binding]; other site
1105113001894	active site
1105113001895	Zn2+ binding site [ion binding]; other site
1105113001896	pyruvate phosphate dikinase; Provisional; Region: PRK09279
1105113001897	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1105113001898	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1105113001899	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1105113001900	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1105113001901	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1105113001902	GSH binding site (G-site) [chemical binding]; other site
1105113001903	C-terminal domain interface [polypeptide binding]; other site
1105113001904	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cd00299
1105113001905	N-terminal domain interface [polypeptide binding]; other site
1105113001906	dimer interface [polypeptide binding]; other site
1105113001907	substrate binding pocket (H-site) [chemical binding]; other site
1105113001908	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP); Region: GATase1_ScBLP_like; cd03144
1105113001909	conserved cys residue [active]
1105113001910	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
1105113001911	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1105113001912	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1105113001913	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1105113001914	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1105113001915	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1105113001916	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
1105113001917	active site
1105113001918	nucleophile elbow; other site
1105113001919	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1105113001920	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1105113001921	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1105113001922	potential frameshift: common BLAST hit: gi|157827542|ref|YP_001496606.1| Phage prohead protease and phage major capsid protein
1105113001923	potential frameshift: common BLAST hit: gi|67459142|ref|YP_246766.1| HK97 family phage prohead protease/phage major capsid protein
1105113001924	Nucleotidyltransferase substrate binding protein like; Region: NTase_sub_bind; pfam08780
1105113001925	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1105113001926	active site
1105113001927	NTP binding site [chemical binding]; other site
1105113001928	metal binding triad [ion binding]; metal-binding site
1105113001929	antibiotic binding site [chemical binding]; other site
1105113001930	Conserved hypothetical protein 2217 (DUF2460); Region: DUF2460; cl02268
1105113001931	Phage conserved hypothetical protein BR0599; Region: Phage_BR0599; pfam09356
1105113001932	Predicted membrane protein [Function unknown]; Region: COG5346
1105113001933	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1105113001934	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1105113001935	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1105113001936	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1105113001937	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; Region: PDHac_trf_mito; TIGR01349
1105113001938	E3 interaction surface; other site
1105113001939	lipoyl attachment site [posttranslational modification]; other site
1105113001940	e3 binding domain; Region: E3_binding; pfam02817
1105113001941	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1105113001942	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1105113001943	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1105113001944	RF-1 domain; Region: RF-1; pfam00472
1105113001945	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1105113001946	DHH family; Region: DHH; pfam01368
1105113001947	DHHA1 domain; Region: DHHA1; pfam02272
1105113001948	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113001949	S-adenosylmethionine binding site [chemical binding]; other site
1105113001950	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105113001951	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1105113001952	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1105113001953	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1105113001954	RNA binding site [nucleotide binding]; other site
1105113001955	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1105113001956	multimer interface [polypeptide binding]; other site
1105113001957	Walker A motif; other site
1105113001958	ATP binding site [chemical binding]; other site
1105113001959	Walker B motif; other site
1105113001960	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1105113001961	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1105113001962	tandem repeat interface [polypeptide binding]; other site
1105113001963	oligomer interface [polypeptide binding]; other site
1105113001964	active site residues [active]
1105113001965	bacterial (prokaryotic) histone like domain; Region: BHL; smart00411
1105113001966	IHF - DNA interface [nucleotide binding]; other site
1105113001967	IHF dimer interface [polypeptide binding]; other site
1105113001968	potential frameshift: common BLAST hit: gi|341583918|ref|YP_004764409.1| putative cytoplasmic protein
1105113001969	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1105113001970	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105113001971	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113001972	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105113001973	synthetase active site [active]
1105113001974	NTP binding site [chemical binding]; other site
1105113001975	metal binding site [ion binding]; metal-binding site
1105113001976	potential frameshift: common BLAST hit: gi|157827431|ref|YP_001496495.1| guanosine polyphosphate pyrophosphohydrolase/synthetase
1105113001977	potential frameshift: common BLAST hit: gi|157827432|ref|YP_001496496.1| Signal transduction histidine kinase
1105113001978	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1105113001979	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105113001980	potential frameshift: common BLAST hit: gi|165933334|ref|YP_001650123.1| transcriptional regulator
1105113001981	Cytidylate kinase [Nucleotide transport and metabolism]; Region: Cmk; COG0283
1105113001982	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1105113001983	CMP-binding site; other site
1105113001984	The sites determining sugar specificity; other site
1105113001985	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1105113001986	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1105113001987	RNA binding site [nucleotide binding]; other site
1105113001988	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1105113001989	RNA binding site [nucleotide binding]; other site
1105113001990	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1105113001991	RNA binding site [nucleotide binding]; other site
1105113001992	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105113001993	RNA binding site [nucleotide binding]; other site
1105113001994	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105113001995	RNA binding site [nucleotide binding]; other site
1105113001996	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1105113001997	RNA binding site [nucleotide binding]; other site
1105113001998	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1105113001999	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1105113002000	oligomer interface [polypeptide binding]; other site
1105113002001	active site residues [active]
1105113002002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105113002003	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1105113002004	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1105113002005	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105113002006	ATP binding site [chemical binding]; other site
1105113002007	Mg2+ binding site [ion binding]; other site
1105113002008	G-X-G motif; other site
1105113002009	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113002010	HD domain; Region: HD_4; pfam13328
1105113002011	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1105113002012	MULE transposase domain; Region: MULE; pfam10551
1105113002013	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
1105113002014	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
1105113002015	homotetramer interface [polypeptide binding]; other site
1105113002016	FMN binding site [chemical binding]; other site
1105113002017	homodimer contacts [polypeptide binding]; other site
1105113002018	putative active site [active]
1105113002019	putative substrate binding site [chemical binding]; other site
1105113002020	Predicted acetyltransferase [General function prediction only]; Region: COG5628
1105113002021	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1105113002022	Coenzyme A binding pocket [chemical binding]; other site
1105113002023	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1105113002024	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1105113002025	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1105113002026	Substrate binding site; other site
1105113002027	Mg++ binding site; other site
1105113002028	hypothetical protein; Validated; Region: PRK00110
1105113002029	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1105113002030	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1105113002031	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1105113002032	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1105113002033	Protein of unknown function (DUF2532); Region: DUF2532; pfam10811
1105113002034	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1105113002035	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1105113002036	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1105113002037	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1105113002038	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113002039	S-adenosylmethionine binding site [chemical binding]; other site
1105113002040	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
1105113002041	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1105113002042	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105113002043	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1105113002044	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
1105113002045	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1105113002046	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
1105113002047	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1105113002048	catalytic site [active]
1105113002049	putative active site [active]
1105113002050	putative substrate binding site [chemical binding]; other site
1105113002051	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1105113002052	Uncharacterized ACR, YagE family COG1723; Region: DUF155; cl00751
1105113002053	Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354
1105113002054	Rickettsial palindromic element RPE2 domain; Region: RPE2; TIGR03774
1105113002055	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1105113002056	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1105113002057	potential frameshift: common BLAST hit: gi|157964645|ref|YP_001499469.1| ankyrin repeat-containing protein
1105113002058	potential frameshift: common BLAST hit: gi|15892625|ref|NP_360339.1| sodium/pantothenate symporter
1105113002059	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105113002060	dimer interface [polypeptide binding]; other site
1105113002061	phosphorylation site [posttranslational modification]
1105113002062	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
1105113002063	ATP binding site [chemical binding]; other site
1105113002064	G-X-G motif; other site
1105113002065	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1105113002066	dimer interface [polypeptide binding]; other site
1105113002067	catalytic triad [active]
1105113002068	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1105113002069	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1105113002070	domain interfaces; other site
1105113002071	active site
1105113002072	potential frameshift: common BLAST hit: gi|157827464|ref|YP_001496528.1| ATPase AAA
1105113002073	Protein of unknown function (DUF497); Region: DUF497; cl01108
1105113002074	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1105113002075	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1105113002076	active site
1105113002077	HIGH motif; other site
1105113002078	dimer interface [polypeptide binding]; other site
1105113002079	KMSKS motif; other site
1105113002080	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1105113002081	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1105113002082	putative acyl-acceptor binding pocket; other site
1105113002083	Protein required for attachment to host cells [Cell motility and secretion]; Region: COG5622
1105113002084	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
1105113002085	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945
1105113002086	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1105113002087	potential frameshift: common BLAST hit: gi|374319403|ref|YP_005065902.1| HemY-like protein
1105113002088	Rickettsial palindromic element RPE2 domain; Region: RPE2; TIGR03774
1105113002089	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1105113002090	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1105113002091	active site
1105113002092	Lysine efflux permease [General function prediction only]; Region: COG1279
1105113002093	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1105113002094	AmpG-like permease; Region: 2A0125; TIGR00901
1105113002095	potential frameshift: common BLAST hit: gi|91206182|ref|YP_538537.1| transposase
1105113002096	potential frameshift: common BLAST hit: gi|67459228|ref|YP_246852.1| lipopolysaccharide 1,2-glucosyltransferase RfaJ
1105113002097	potential frameshift: common BLAST hit: gi|157825832|ref|YP_001493552.1| lipopolysaccharide 1,2-glucosyltransferase RfaJ
1105113002098	potential frameshift: common BLAST hit: gi|67459228|ref|YP_246852.1| lipopolysaccharide 1,2-glucosyltransferase RfaJ
1105113002099	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105113002100	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1105113002101	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1105113002102	substrate binding pocket [chemical binding]; other site
1105113002103	chain length determination region; other site
1105113002104	substrate-Mg2+ binding site; other site
1105113002105	catalytic residues [active]
1105113002106	aspartate-rich region 1; other site
1105113002107	active site lid residues [active]
1105113002108	aspartate-rich region 2; other site
1105113002109	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1105113002110	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1105113002111	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113002112	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
1105113002113	active site
1105113002114	arginine:agmatin antiporter; Provisional; Region: PRK10644
1105113002115	DNA topoisomerase 2; Provisional; Region: PLN03237
1105113002116	Iron-sulfur cluster assembly accessory protein; Region: TIGR00049
1105113002117	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1105113002118	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1105113002119	trimerization site [polypeptide binding]; other site
1105113002120	active site
1105113002121	cysteine desulfurase; Provisional; Region: PRK14012
1105113002122	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1105113002123	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1105113002124	catalytic residue [active]
1105113002125	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1105113002126	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1105113002127	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1105113002128	catalytic residue [active]
1105113002129	Predicted transcriptional regulator [Transcription]; Region: COG1959
1105113002130	iron-sulfur cluster assembly transcription factor IscR; Region: IscR; TIGR02010
1105113002131	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105113002132	NADH dehydrogenase subunit 2; Provisional; Region: ND2; MTH00196
1105113002133	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105113002134	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
1105113002135	dimer interface [polypeptide binding]; other site
1105113002136	allosteric magnesium binding site [ion binding]; other site
1105113002137	active site
1105113002138	aspartate-rich active site metal binding site; other site
1105113002139	Schiff base residues; other site
1105113002140	primosome assembly protein PriA; Validated; Region: PRK05580
1105113002141	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105113002142	ATP binding site [chemical binding]; other site
1105113002143	putative Mg++ binding site [ion binding]; other site
1105113002144	nucleotide binding region [chemical binding]; other site
1105113002145	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1105113002146	ATP-binding site [chemical binding]; other site
1105113002147	polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases; Region: ubiX_pad; TIGR00421
1105113002148	Flavoprotein; Region: Flavoprotein; pfam02441
1105113002149	replicative DNA helicase; Provisional; Region: PRK09165
1105113002150	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1105113002151	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1105113002152	Walker A motif; other site
1105113002153	ATP binding site [chemical binding]; other site
1105113002154	Walker B motif; other site
1105113002155	DNA binding loops [nucleotide binding]
1105113002156	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1105113002157	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1105113002158	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105113002159	RNA binding surface [nucleotide binding]; other site
1105113002160	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1105113002161	active site
1105113002162	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1105113002163	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1105113002164	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1105113002165	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1105113002166	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1105113002167	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1105113002168	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1105113002169	S-adenosylmethionine binding site [chemical binding]; other site
1105113002170	DNA repair protein RadA; Provisional; Region: PRK11823
1105113002171	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1105113002172	Walker A motif/ATP binding site; other site
1105113002173	ATP binding site [chemical binding]; other site
1105113002174	Walker B motif; other site
1105113002175	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1105113002176	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1105113002177	Recombination protein O N terminal; Region: RecO_N; pfam11967
1105113002178	Recombination protein O C terminal; Region: RecO_C; pfam02565
1105113002179	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1105113002180	Glycoprotease family; Region: Peptidase_M22; pfam00814
1105113002181	translation initiation factor IF-2; Validated; Region: infB; PRK05306
1105113002182	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1105113002183	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1105113002184	G1 box; other site
1105113002185	putative GEF interaction site [polypeptide binding]; other site
1105113002186	GTP/Mg2+ binding site [chemical binding]; other site
1105113002187	Switch I region; other site
1105113002188	G2 box; other site
1105113002189	G3 box; other site
1105113002190	Switch II region; other site
1105113002191	G4 box; other site
1105113002192	G5 box; other site
1105113002193	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1105113002194	Translation-initiation factor 2; Region: IF-2; pfam11987
1105113002195	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1105113002196	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1105113002197	NusA N-terminal domain; Region: NusA_N; pfam08529
1105113002198	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1105113002199	RNA binding site [nucleotide binding]; other site
1105113002200	homodimer interface [polypeptide binding]; other site
1105113002201	NusA-like KH domain; Region: KH_5; pfam13184
1105113002202	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1105113002203	G-X-X-G motif; other site
1105113002204	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1105113002205	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG0779
1105113002206	Sm and related proteins; Region: Sm_like; cl00259
1105113002207	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1105113002208	putative oligomer interface [polypeptide binding]; other site
1105113002209	putative RNA binding site [nucleotide binding]; other site
1105113002210	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
1105113002211	FAD binding pocket [chemical binding]; other site
1105113002212	conserved FAD binding motif [chemical binding]; other site
1105113002213	phosphate binding motif [ion binding]; other site
1105113002214	beta-alpha-beta structure motif; other site
1105113002215	NAD binding pocket [chemical binding]; other site
1105113002216	Predicted transcriptional regulator [Transcription]; Region: COG1959
1105113002217	Transcriptional regulator; Region: Rrf2; cl17282
1105113002218	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1105113002219	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105113002220	RNA binding surface [nucleotide binding]; other site
1105113002221	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1105113002222	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1105113002223	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1105113002224	active site
1105113002225	HIGH motif; other site
1105113002226	dimer interface [polypeptide binding]; other site
1105113002227	KMSKS motif; other site
1105113002228	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1105113002229	RNA binding surface [nucleotide binding]; other site
1105113002230	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5304
1105113002231	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1105113002232	active site
1105113002233	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1105113002234	TraB family; Region: TraB; cl12050
1105113002235	potential frameshift: common BLAST hit: gi|157826966|ref|YP_001496030.1| guanosine polyphosphate pyrophosphohydrolase/synthetase
1105113002236	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1105113002237	active site
1105113002238	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK06617
1105113002239	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1105113002240	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12612
1105113002241	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1105113002242	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1105113002243	active site
1105113002244	phosphorylation site [posttranslational modification]
1105113002245	intermolecular recognition site; other site
1105113002246	dimerization interface [polypeptide binding]; other site
1105113002247	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113002248	Walker A motif; other site
1105113002249	ATP binding site [chemical binding]; other site
1105113002250	Walker B motif; other site
1105113002251	arginine finger; other site
1105113002252	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1105113002253	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1105113002254	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
1105113002255	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1105113002256	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264
1105113002257	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1105113002258	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1105113002259	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1105113002260	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1105113002261	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1105113002262	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1105113002263	Predicted secreted (periplasmic) protein [Function unknown]; Region: COG5462
1105113002264	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1105113002265	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113002266	S-adenosylmethionine binding site [chemical binding]; other site
1105113002267	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2001
1105113002268	MraZ protein; Region: MraZ; pfam02381
1105113002269	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
1105113002270	Na binding site [ion binding]; other site
1105113002271	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1105113002272	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1105113002273	GIY-YIG motif/motif A; other site
1105113002274	active site
1105113002275	catalytic site [active]
1105113002276	putative DNA binding site [nucleotide binding]; other site
1105113002277	metal binding site [ion binding]; metal-binding site
1105113002278	UvrB/uvrC motif; Region: UVR; pfam02151
1105113002279	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1105113002280	Copper(I)-binding protein [Inorganic ion transport and    metabolism]; Region: COG2847
1105113002281	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1105113002282	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1105113002283	DNA binding site [nucleotide binding]
1105113002284	active site
1105113002285	HEPN domain; Region: HEPN; cl00824
1105113002286	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1105113002287	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1105113002288	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1105113002289	SEC-C motif; Region: SEC-C; pfam02810
1105113002290	peptidylprolyl isomerase; Reviewed; Region: prsA; PRK03095
1105113002291	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1105113002292	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1105113002293	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1105113002294	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1105113002295	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1105113002296	hinge; other site
1105113002297	active site
1105113002298	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1105113002299	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105113002300	ATP binding site [chemical binding]; other site
1105113002301	Mg2+ binding site [ion binding]; other site
1105113002302	G-X-G motif; other site
1105113002303	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1105113002304	anchoring element; other site
1105113002305	dimer interface [polypeptide binding]; other site
1105113002306	ATP binding site [chemical binding]; other site
1105113002307	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1105113002308	active site
1105113002309	putative metal-binding site [ion binding]; other site
1105113002310	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1105113002311	HAD-superfamily class IIA hydrolase, TIGR01459; Region: HAD-SF-IIA-hyp4
1105113002312	Haloacid dehalogenase-like hydrolase; Region: Hydrolase_6; pfam13344
1105113002313	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1105113002314	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1105113002315	MgtE intracellular N domain; Region: MgtE_N; pfam03448
1105113002316	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1105113002317	Divalent cation transporter; Region: MgtE; pfam01769
1105113002318	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113002319	HD domain; Region: HD_4; pfam13328
1105113002320	Rickettsial palindromic element RPE5 domain; Region: RPE5; TIGR03776
1105113002321	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1105113002322	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1105113002323	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1105113002324	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1105113002325	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1105113002326	Cu(I) binding site [ion binding]; other site
1105113002327	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13254
1105113002328	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1105113002329	dimer interface [polypeptide binding]; other site
1105113002330	substrate binding site [chemical binding]; other site
1105113002331	metal binding sites [ion binding]; metal-binding site
1105113002332	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113002333	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1105113002334	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1105113002335	TraX protein; Region: TraX; pfam05857
1105113002336	RecG-like helicase [DNA replication, recombination, and repair / Transcription]; Region: RecG; COG1200
1105113002337	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1105113002338	ssDNA binding site; other site
1105113002339	generic binding surface II; other site
1105113002340	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105113002341	ATP binding site [chemical binding]; other site
1105113002342	putative Mg++ binding site [ion binding]; other site
1105113002343	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105113002344	nucleotide binding region [chemical binding]; other site
1105113002345	ATP-binding site [chemical binding]; other site
1105113002346	Coenzyme A transferase; Region: CoA_trans; cl17247
1105113002347	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1105113002348	potential frameshift: common BLAST hit: gi|350273748|ref|YP_004885061.1| succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B
1105113002349	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1105113002350	V-type ATP synthase subunit I; Validated; Region: PRK05771
1105113002351	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1105113002352	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1105113002353	Mg++ binding site [ion binding]; other site
1105113002354	putative catalytic motif [active]
1105113002355	putative substrate binding site [chemical binding]; other site
1105113002356	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1105113002357	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
1105113002358	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105113002359	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105113002360	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1105113002361	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1105113002362	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1105113002363	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1105113002364	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1105113002365	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1105113002366	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1105113002367	ATP binding site [chemical binding]; other site
1105113002368	putative Mg++ binding site [ion binding]; other site
1105113002369	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105113002370	nucleotide binding region [chemical binding]; other site
1105113002371	ATP-binding site [chemical binding]; other site
1105113002372	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1105113002373	Uncharacterized conserved protein [Function unknown]; Region: COG2938
1105113002374	Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins; Region: RHOD_1; cd01522
1105113002375	active site residue [active]
1105113002376	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1105113002377	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105113002378	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113002379	Walker A motif; other site
1105113002380	ATP binding site [chemical binding]; other site
1105113002381	Walker B motif; other site
1105113002382	arginine finger; other site
1105113002383	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1105113002384	DnaA box-binding interface [nucleotide binding]; other site
1105113002385	Patatin [General function prediction only]; Region: COG3621
1105113002386	Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Region: Pat17_PNPLA8_PNPLA9_like; cd07199
1105113002387	active site
1105113002388	nucleophile elbow; other site
1105113002389	HEPN domain; Region: HEPN; cl00824
1105113002390	GTP-binding protein YchF; Reviewed; Region: PRK09601
1105113002391	YchF GTPase; Region: YchF; cd01900
1105113002392	G1 box; other site
1105113002393	GTP/Mg2+ binding site [chemical binding]; other site
1105113002394	Switch I region; other site
1105113002395	G2 box; other site
1105113002396	Switch II region; other site
1105113002397	G3 box; other site
1105113002398	G4 box; other site
1105113002399	G5 box; other site
1105113002400	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1105113002401	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1105113002402	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1105113002403	putative active site [active]
1105113002404	catalytic residue [active]
1105113002405	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1105113002406	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1105113002407	5S rRNA interface [nucleotide binding]; other site
1105113002408	CTC domain interface [polypeptide binding]; other site
1105113002409	L16 interface [polypeptide binding]; other site
1105113002410	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1105113002411	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105113002412	FeS/SAM binding site; other site
1105113002413	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1105113002414	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1105113002415	23S rRNA binding site [nucleotide binding]; other site
1105113002416	L21 binding site [polypeptide binding]; other site
1105113002417	L13 binding site [polypeptide binding]; other site
1105113002418	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1105113002419	ribonuclease P; Reviewed; Region: rnpA; PRK01492
1105113002420	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1105113002421	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1105113002422	uncharacterized subgroup of the Escherichia coli Mg2+ transporter CorA_like subfamily; Region: EcCorA-like_u1; cd12837
1105113002423	Cl binding site [ion binding]; other site
1105113002424	oligomer interface [polypeptide binding]; other site
1105113002425	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113002426	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113002427	potential frameshift: common BLAST hit: gi|15892870|ref|NP_360584.1| aminoglycoside 3-N-acetyltransferase
1105113002428	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1105113002429	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]; Region: NtrY; COG5000
1105113002430	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1105113002431	dimerization interface [polypeptide binding]; other site
1105113002432	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1105113002433	dimer interface [polypeptide binding]; other site
1105113002434	phosphorylation site [posttranslational modification]
1105113002435	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1105113002436	ATP binding site [chemical binding]; other site
1105113002437	Mg2+ binding site [ion binding]; other site
1105113002438	G-X-G motif; other site
1105113002439	Ribosomal protein S21 [Translation, ribosomal structure and biogenesis]; Region: RpsU; COG0828
1105113002440	Uncharacterized conserved protein [Function unknown]; Region: COG5590
1105113002441	COQ9; Region: COQ9; pfam08511
1105113002442	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
1105113002443	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1105113002444	HIGH motif; other site
1105113002445	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1105113002446	active site
1105113002447	KMSKS motif; other site
1105113002448	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1105113002449	tRNA binding surface [nucleotide binding]; other site
1105113002450	anticodon binding site; other site
1105113002451	Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770
1105113002452	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1105113002453	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1105113002454	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1105113002455	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1105113002456	carboxyltransferase (CT) interaction site; other site
1105113002457	biotinylation site [posttranslational modification]; other site
1105113002458	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1105113002459	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1105113002460	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1105113002461	acylglycerophosphoethanolamine acyltransferase; Provisional; Region: PRK06814
1105113002462	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105113002463	putative substrate translocation pore; other site
1105113002464	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1105113002465	putative acyl-acceptor binding pocket; other site
1105113002466	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1105113002467	acyl-activating enzyme (AAE) consensus motif; other site
1105113002468	putative AMP binding site [chemical binding]; other site
1105113002469	TfoX N-terminal domain; Region: TfoX_N; cl17592
1105113002470	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1105113002471	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1105113002472	ABC-ATPase subunit  interface; other site
1105113002473	dimer interface [polypeptide binding]; other site
1105113002474	putative PBP binding regions; other site
1105113002475	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1105113002476	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113002477	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113002478	S-adenosylmethionine binding site [chemical binding]; other site
1105113002479	glutamyl-tRNA synthetase; Provisional; Region: gltX; PRK14895
1105113002480	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105113002481	HIGH motif; other site
1105113002482	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1105113002483	active site
1105113002484	KMSKS motif; other site
1105113002485	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113002486	Invasion protein B, involved in pathogenesis [General function prediction only]; Region: COG5342
1105113002487	Chitin binding domain; Region: Chitin_bind_3; cl03871
1105113002488	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113002489	HD domain; Region: HD_4; pfam13328
1105113002490	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113002491	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105113002492	synthetase active site [active]
1105113002493	NTP binding site [chemical binding]; other site
1105113002494	metal binding site [ion binding]; metal-binding site
1105113002495	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1105113002496	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1105113002497	ring oligomerisation interface [polypeptide binding]; other site
1105113002498	ATP/Mg binding site [chemical binding]; other site
1105113002499	stacking interactions; other site
1105113002500	hinge regions; other site
1105113002501	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1105113002502	oligomerisation interface [polypeptide binding]; other site
1105113002503	mobile loop; other site
1105113002504	roof hairpin; other site
1105113002505	potential frameshift: common BLAST hit: gi|67458799|ref|YP_246423.1| glycosyltransferase
1105113002506	potential frameshift: common BLAST hit: gi|67458799|ref|YP_246423.1| glycosyltransferase
1105113002507	ribonuclease PH; Reviewed; Region: rph; PRK00173
1105113002508	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1105113002509	hexamer interface [polypeptide binding]; other site
1105113002510	active site
1105113002511	GrpE; Region: GrpE; pfam01025
1105113002512	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1105113002513	dimer interface [polypeptide binding]; other site
1105113002514	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1105113002515	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1105113002516	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1105113002517	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1105113002518	hypothetical protein; Validated; Region: PRK06620
1105113002519	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105113002520	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105113002521	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113002522	HD domain; Region: HD_4; pfam13328
1105113002523	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1105113002524	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
1105113002525	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1105113002526	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1105113002527	alphaNTD - beta interaction site [polypeptide binding]; other site
1105113002528	alphaNTD homodimer interface [polypeptide binding]; other site
1105113002529	alphaNTD - beta' interaction site [polypeptide binding]; other site
1105113002530	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1105113002531	30S ribosomal protein S11; Validated; Region: PRK05309
1105113002532	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
1105113002533	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1105113002534	adenylate kinase; Reviewed; Region: adk; PRK00279
1105113002535	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1105113002536	AMP-binding site [chemical binding]; other site
1105113002537	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1105113002538	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1105113002539	SecY translocase; Region: SecY; pfam00344
1105113002540	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1105113002541	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1105113002542	23S rRNA binding site [nucleotide binding]; other site
1105113002543	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1105113002544	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1105113002545	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1105113002546	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1105113002547	5S rRNA interface [nucleotide binding]; other site
1105113002548	23S rRNA interface [nucleotide binding]; other site
1105113002549	L5 interface [polypeptide binding]; other site
1105113002550	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1105113002551	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1105113002552	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1105113002553	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1105113002554	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1105113002555	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1105113002556	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1105113002557	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1105113002558	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1105113002559	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1105113002560	RNA binding site [nucleotide binding]; other site
1105113002561	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1105113002562	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1105113002563	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1105113002564	L23 interface [polypeptide binding]; other site
1105113002565	trigger factor interaction site; other site
1105113002566	23S rRNA interface [nucleotide binding]; other site
1105113002567	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1105113002568	23S rRNA interface [nucleotide binding]; other site
1105113002569	5S rRNA interface [nucleotide binding]; other site
1105113002570	putative antibiotic binding site [chemical binding]; other site
1105113002571	L25 interface [polypeptide binding]; other site
1105113002572	L27 interface [polypeptide binding]; other site
1105113002573	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1105113002574	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1105113002575	G-X-X-G motif; other site
1105113002576	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1105113002577	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1105113002578	putative translocon binding site; other site
1105113002579	protein-rRNA interface [nucleotide binding]; other site
1105113002580	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1105113002581	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1105113002582	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1105113002583	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1105113002584	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1105113002585	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1105113002586	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1105113002587	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1105113002588	elongation factor Tu; Reviewed; Region: PRK00049
1105113002589	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1105113002590	G1 box; other site
1105113002591	GEF interaction site [polypeptide binding]; other site
1105113002592	GTP/Mg2+ binding site [chemical binding]; other site
1105113002593	Switch I region; other site
1105113002594	G2 box; other site
1105113002595	G3 box; other site
1105113002596	Switch II region; other site
1105113002597	G4 box; other site
1105113002598	G5 box; other site
1105113002599	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1105113002600	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1105113002601	Antibiotic Binding Site [chemical binding]; other site
1105113002602	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1105113002603	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1105113002604	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1105113002605	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1105113002606	Class II fumarases; Region: Fumarase_classII; cd01362
1105113002607	active site
1105113002608	tetramer interface [polypeptide binding]; other site
1105113002609	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
1105113002610	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
1105113002611	putative active site [active]
1105113002612	homotetrameric interface [polypeptide binding]; other site
1105113002613	metal binding site [ion binding]; metal-binding site
1105113002614	cell division protein FtsZ; Validated; Region: PRK09330
1105113002615	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1105113002616	nucleotide binding site [chemical binding]; other site
1105113002617	SulA interaction site; other site
1105113002618	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cl00178
1105113002619	primary substrate binding site; other site
1105113002620	inhibition loop; other site
1105113002621	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; smart00932
1105113002622	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1105113002623	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1105113002624	muropeptide transporter; Validated; Region: ampG; cl17669
1105113002625	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1105113002626	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1105113002627	ATP binding site [chemical binding]; other site
1105113002628	Mg++ binding site [ion binding]; other site
1105113002629	motif III; other site
1105113002630	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1105113002631	nucleotide binding region [chemical binding]; other site
1105113002632	ATP-binding site [chemical binding]; other site
1105113002633	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1105113002634	DNA-binding site [nucleotide binding]; DNA binding site
1105113002635	RNA-binding motif; other site
1105113002636	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1105113002637	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113002638	S-adenosylmethionine binding site [chemical binding]; other site
1105113002639	SurA N-terminal domain; Region: SurA_N_3; cl07813
1105113002640	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1105113002641	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1105113002642	Exonuclease VII, large subunit [DNA replication, recombination, and repair]; Region: XseA; COG1570
1105113002643	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1105113002644	generic binding surface II; other site
1105113002645	generic binding surface I; other site
1105113002646	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1105113002647	putative catalytic site [active]
1105113002648	putative phosphate binding site [ion binding]; other site
1105113002649	active site
1105113002650	metal binding site A [ion binding]; metal-binding site
1105113002651	DNA binding site [nucleotide binding]
1105113002652	putative AP binding site [nucleotide binding]; other site
1105113002653	putative metal binding site B [ion binding]; other site
1105113002654	Uncharacterized conserved protein [Function unknown]; Region: COG4095
1105113002655	GTP-binding protein Der; Reviewed; Region: PRK00093
1105113002656	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1105113002657	G1 box; other site
1105113002658	GTP/Mg2+ binding site [chemical binding]; other site
1105113002659	Switch I region; other site
1105113002660	G2 box; other site
1105113002661	Switch II region; other site
1105113002662	G3 box; other site
1105113002663	G4 box; other site
1105113002664	G5 box; other site
1105113002665	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1105113002666	G1 box; other site
1105113002667	GTP/Mg2+ binding site [chemical binding]; other site
1105113002668	Switch I region; other site
1105113002669	G2 box; other site
1105113002670	G3 box; other site
1105113002671	Switch II region; other site
1105113002672	G4 box; other site
1105113002673	G5 box; other site
1105113002674	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1105113002675	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113002676	Walker A motif; other site
1105113002677	ATP binding site [chemical binding]; other site
1105113002678	Walker B motif; other site
1105113002679	arginine finger; other site
1105113002680	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1105113002681	ABC1 family; Region: ABC1; cl17513
1105113002682	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1105113002683	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113002684	S-adenosylmethionine binding site [chemical binding]; other site
1105113002685	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1105113002686	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1105113002687	DNA binding site [nucleotide binding]
1105113002688	catalytic residue [active]
1105113002689	H2TH interface [polypeptide binding]; other site
1105113002690	putative catalytic residues [active]
1105113002691	turnover-facilitating residue; other site
1105113002692	intercalation triad [nucleotide binding]; other site
1105113002693	8OG recognition residue [nucleotide binding]; other site
1105113002694	putative reading head residues; other site
1105113002695	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1105113002696	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1105113002697	potential frameshift: common BLAST hit: gi|67458633|ref|YP_246257.1| mannose-1-phosphate guanylyltransferase
1105113002698	Poly-beta-hydroxyalkanoate depolymerase [Lipid metabolism]; Region: DepA; COG4553
1105113002699	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1105113002700	active site
1105113002701	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
1105113002702	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1105113002703	HIGH motif; other site
1105113002704	active site
1105113002705	KMSKS motif; other site
1105113002706	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1105113002707	tRNA binding surface [nucleotide binding]; other site
1105113002708	anticodon binding site; other site
1105113002709	thymidylate kinase; Validated; Region: tmk; PRK00698
1105113002710	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1105113002711	TMP-binding site; other site
1105113002712	ATP-binding site [chemical binding]; other site
1105113002713	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105113002714	4-hydroxybenzoate polyprenyltransferase; Reviewed; Region: ubiA; PRK12847
1105113002715	UbiA prenyltransferase family; Region: UbiA; pfam01040
1105113002716	potential frameshift: common BLAST hit: gi|350273815|ref|YP_004885128.1| transposase
1105113002717	valyl-tRNA synthetase; Reviewed; Region: valS; PRK13208
1105113002718	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105113002719	active site
1105113002720	HIGH motif; other site
1105113002721	nucleotide binding site [chemical binding]; other site
1105113002722	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1105113002723	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1105113002724	active site
1105113002725	KMSKS motif; other site
1105113002726	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1105113002727	tRNA binding surface [nucleotide binding]; other site
1105113002728	anticodon binding site; other site
1105113002729	LPS biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3475
1105113002730	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1105113002731	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
1105113002732	RmuC family; Region: RmuC; pfam02646
1105113002733	potential frameshift: common BLAST hit: gi|157964841|ref|YP_001499665.1| putative oxidoreductase protein
1105113002734	Predicted integral membrane protein (DUF2269); Region: DUF2269; pfam10027
1105113002735	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1105113002736	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1105113002737	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1105113002738	Walker A motif; other site
1105113002739	ATP binding site [chemical binding]; other site
1105113002740	Walker B motif; other site
1105113002741	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1105113002742	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1105113002743	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1105113002744	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1105113002745	Ligand Binding Site [chemical binding]; other site
1105113002746	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
1105113002747	HicB family; Region: HicB; pfam05534
1105113002748	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
1105113002749	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1105113002750	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113002751	Walker A/P-loop; other site
1105113002752	ATP binding site [chemical binding]; other site
1105113002753	Q-loop/lid; other site
1105113002754	ABC transporter signature motif; other site
1105113002755	Walker B; other site
1105113002756	D-loop; other site
1105113002757	H-loop/switch region; other site
1105113002758	Protein of unknown function (DUF2673); Region: DUF2673; pfam10880
1105113002759	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105113002760	putative substrate translocation pore; other site
1105113002761	lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212
1105113002762	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1105113002763	FtsX-like permease family; Region: FtsX; pfam02687
1105113002764	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1105113002765	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1105113002766	Walker A/P-loop; other site
1105113002767	ATP binding site [chemical binding]; other site
1105113002768	Q-loop/lid; other site
1105113002769	ABC transporter signature motif; other site
1105113002770	Walker B; other site
1105113002771	D-loop; other site
1105113002772	H-loop/switch region; other site
1105113002773	Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536
1105113002774	Domain of unknown function DUF21; Region: DUF21; pfam01595
1105113002775	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1105113002776	Transporter associated domain; Region: CorC_HlyC; smart01091
1105113002777	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
1105113002778	Rickettsia outer membrane protein B; Region: rOmpB; pfam12334
1105113002779	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1105113002780	Autotransporter beta-domain; Region: Autotransporter; smart00869
1105113002781	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113002782	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105113002783	synthetase active site [active]
1105113002784	NTP binding site [chemical binding]; other site
1105113002785	metal binding site [ion binding]; metal-binding site
1105113002786	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1105113002787	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1105113002788	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1105113002789	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1105113002790	DNA binding residues [nucleotide binding]
1105113002791	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1105113002792	IHF - DNA interface [nucleotide binding]; other site
1105113002793	IHF dimer interface [polypeptide binding]; other site
1105113002794	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1105113002795	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1105113002796	catalytic triad [active]
1105113002797	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1105113002798	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1105113002799	putative acyl-acceptor binding pocket; other site
1105113002800	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1105113002801	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1105113002802	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1105113002803	Peptidase family M23; Region: Peptidase_M23; pfam01551
1105113002804	Protein of unknown function (DUF519); Region: DUF519; pfam04378
1105113002805	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1105113002806	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1105113002807	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1105113002808	nucleotide binding pocket [chemical binding]; other site
1105113002809	K-X-D-G motif; other site
1105113002810	catalytic site [active]
1105113002811	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1105113002812	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1105113002813	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1105113002814	Dimer interface [polypeptide binding]; other site
1105113002815	BRCT sequence motif; other site
1105113002816	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1105113002817	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1105113002818	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1105113002819	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113002820	potential frameshift: common BLAST hit: gi|341584274|ref|YP_004764765.1| guanosine polyphosphate pyrophosphohydrolase/synthetase
1105113002821	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105113002822	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1105113002823	mce related protein; Region: MCE; pfam02470
1105113002824	hypothetical protein; Provisional; Region: PRK06630
1105113002825	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1105113002826	RNA/DNA hybrid binding site [nucleotide binding]; other site
1105113002827	active site
1105113002828	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3814
1105113002829	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3494
1105113002830	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1105113002831	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1105113002832	CoA-binding site [chemical binding]; other site
1105113002833	ATP-binding [chemical binding]; other site
1105113002834	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1105113002835	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1105113002836	active site
1105113002837	catalytic site [active]
1105113002838	substrate binding site [chemical binding]; other site
1105113002839	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
1105113002840	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1105113002841	Part of AAA domain; Region: AAA_19; pfam13245
1105113002842	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1105113002843	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
1105113002844	Family description; Region: UvrD_C_2; pfam13538
1105113002845	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1105113002846	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1105113002847	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1105113002848	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529
1105113002849	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cl02529
1105113002850	potential frameshift: common BLAST hit: gi|67458557|ref|YP_246181.1| superfamily I DNA/RNA helicase
1105113002851	potential frameshift: common BLAST hit: gi|67458557|ref|YP_246181.1| superfamily I DNA/RNA helicase
1105113002852	potential frameshift: common BLAST hit: gi|67458557|ref|YP_246181.1| superfamily I DNA/RNA helicase
1105113002853	potential frameshift: common BLAST hit: gi|350273857|ref|YP_004885170.1| acetyl-CoA acetyltransferase
1105113002854	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
1105113002855	Uncharacterized conserved protein (DUF2048); Region: DUF2048; pfam09752
1105113002856	TLC ATP/ADP transporter; Region: TLC; pfam03219
1105113002857	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a...; Region: Nudix_Hydrolase_1; cd03674
1105113002858	nudix motif; other site
1105113002859	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1105113002860	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1105113002861	Transporter associated domain; Region: CorC_HlyC; smart01091
1105113002862	metal-binding heat shock protein; Provisional; Region: PRK00016
1105113002863	lipoyl synthase; Provisional; Region: PRK05481
1105113002864	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105113002865	FeS/SAM binding site; other site
1105113002866	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1105113002867	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1105113002868	dimer interface [polypeptide binding]; other site
1105113002869	active site
1105113002870	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1105113002871	folate binding site [chemical binding]; other site
1105113002872	Predicted esterase [General function prediction only]; Region: COG0400
1105113002873	putative hydrolase; Provisional; Region: PRK11460
1105113002874	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1105113002875	putative GSH binding site [chemical binding]; other site
1105113002876	catalytic residues [active]
1105113002877	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1105113002878	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1105113002879	minor groove reading motif; other site
1105113002880	helix-hairpin-helix signature motif; other site
1105113002881	substrate binding pocket [chemical binding]; other site
1105113002882	active site
1105113002883	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1105113002884	Predicted small secreted protein [Function unknown]; Region: COG5510
1105113002885	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1105113002886	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1105113002887	Predicted methyltransferases [General function prediction only]; Region: COG0313
1105113002888	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1105113002889	putative SAM binding site [chemical binding]; other site
1105113002890	putative homodimer interface [polypeptide binding]; other site
1105113002891	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1105113002892	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1105113002893	putative ligand binding site [chemical binding]; other site
1105113002894	twin arginine translocase protein A; Provisional; Region: tatA; PRK01470
1105113002895	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1105113002896	tetramer interfaces [polypeptide binding]; other site
1105113002897	binuclear metal-binding site [ion binding]; other site
1105113002898	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1105113002899	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1105113002900	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1105113002901	aspartate kinase; Reviewed; Region: PRK06635
1105113002902	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1105113002903	putative nucleotide binding site [chemical binding]; other site
1105113002904	putative catalytic residues [active]
1105113002905	putative Mg ion binding site [ion binding]; other site
1105113002906	putative aspartate binding site [chemical binding]; other site
1105113002907	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1105113002908	putative allosteric regulatory residue; other site
1105113002909	Helix-turn-helix XRE-family like proteins; Region: HTH_XRE; smart00530
1105113002910	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA; cl01007
1105113002911	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13541
1105113002912	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1105113002913	Walker A/P-loop; other site
1105113002914	ATP binding site [chemical binding]; other site
1105113002915	Q-loop/lid; other site
1105113002916	ABC transporter signature motif; other site
1105113002917	Walker B; other site
1105113002918	D-loop; other site
1105113002919	H-loop/switch region; other site
1105113002920	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1105113002921	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105113002922	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1105113002923	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1105113002924	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1105113002925	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1105113002926	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1105113002927	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00213
1105113002928	Predicted transcriptional regulator [Transcription]; Region: COG2944
1105113002929	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105113002930	salt bridge; other site
1105113002931	non-specific DNA binding site [nucleotide binding]; other site
1105113002932	sequence-specific DNA binding site [nucleotide binding]; other site
1105113002933	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
1105113002934	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1105113002935	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1105113002936	S-adenosylmethionine binding site [chemical binding]; other site
1105113002937	Predicted regulatory domain of a methyltransferase [General function prediction only]; Region: COG4797
1105113002938	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1105113002939	Integral membrane protein TerC family; Region: TerC; cl10468
1105113002940	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
1105113002941	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
1105113002942	Rickettsial palindromic element RPE5 domain; Region: RPE5; TIGR03776
1105113002943	seryl-tRNA synthetase; Provisional; Region: PRK05431
1105113002944	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1105113002945	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1105113002946	dimer interface [polypeptide binding]; other site
1105113002947	active site
1105113002948	motif 1; other site
1105113002949	motif 2; other site
1105113002950	motif 3; other site
1105113002951	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1105113002952	muropeptide transporter; Validated; Region: ampG; cl17669
1105113002953	Protein of unknown function; Region: DUF3971; pfam13116
1105113002954	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1105113002955	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1105113002956	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1105113002957	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1105113002958	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1105113002959	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1105113002960	putative active site [active]
1105113002961	putative PHP Thumb interface [polypeptide binding]; other site
1105113002962	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1105113002963	generic binding surface I; other site
1105113002964	generic binding surface II; other site
1105113002965	Protein of unknown function, DUF412; Region: DUF412; cl01183
1105113002966	potential frameshift: common BLAST hit: gi|157826229|ref|YP_001493949.1| S-adenosylmethionine synthetase
1105113002967	DNA polymerase I; Provisional; Region: PRK05755
1105113002968	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1105113002969	active site
1105113002970	metal binding site 1 [ion binding]; metal-binding site
1105113002971	putative 5' ssDNA interaction site; other site
1105113002972	metal binding site 3; metal-binding site
1105113002973	metal binding site 2 [ion binding]; metal-binding site
1105113002974	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1105113002975	putative DNA binding site [nucleotide binding]; other site
1105113002976	putative metal binding site [ion binding]; other site
1105113002977	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1105113002978	active site
1105113002979	substrate binding site [chemical binding]; other site
1105113002980	catalytic site [active]
1105113002981	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1105113002982	active site
1105113002983	DNA binding site [nucleotide binding]
1105113002984	catalytic site [active]
1105113002985	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1105113002986	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1105113002987	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1105113002988	P loop; other site
1105113002989	GTP binding site [chemical binding]; other site
1105113002990	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
1105113002991	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1105113002992	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
1105113002993	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1105113002994	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1105113002995	dimer interface [polypeptide binding]; other site
1105113002996	active site
1105113002997	CoA binding pocket [chemical binding]; other site
1105113002998	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1105113002999	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1105113003000	ligand binding site [chemical binding]; other site
1105113003001	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1105113003002	Predicted permeases [General function prediction only]; Region: COG0795
1105113003003	rod shape-determining protein MreB; Provisional; Region: PRK13927
1105113003004	MreB and similar proteins; Region: MreB_like; cd10225
1105113003005	nucleotide binding site [chemical binding]; other site
1105113003006	Mg binding site [ion binding]; other site
1105113003007	putative protofilament interaction site [polypeptide binding]; other site
1105113003008	RodZ interaction site [polypeptide binding]; other site
1105113003009	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
1105113003010	rod shape-determining protein MreC; Region: MreC; pfam04085
1105113003011	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1105113003012	sequence-specific DNA binding site [nucleotide binding]; other site
1105113003013	salt bridge; other site
1105113003014	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113003015	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1105113003016	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1105113003017	catalytic site [active]
1105113003018	G-X2-G-X-G-K; other site
1105113003019	AAA domain; Region: AAA_14; pfam13173
1105113003020	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1105113003021	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1105113003022	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105113003023	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1105113003024	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1105113003025	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1105113003026	dimer interface [polypeptide binding]; other site
1105113003027	active site
1105113003028	acyl carrier protein; Provisional; Region: acpP; PRK00982
1105113003029	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1105113003030	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1105113003031	NAD(P) binding site [chemical binding]; other site
1105113003032	homotetramer interface [polypeptide binding]; other site
1105113003033	homodimer interface [polypeptide binding]; other site
1105113003034	active site
1105113003035	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1105113003036	RecA/RadA recombinase [DNA replication, recombination, and repair]; Region: RecA; COG0468
1105113003037	hexamer interface [polypeptide binding]; other site
1105113003038	Walker A motif; other site
1105113003039	ATP binding site [chemical binding]; other site
1105113003040	Walker B motif; other site
1105113003041	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105113003042	putative substrate translocation pore; other site
1105113003043	potential frameshift: common BLAST hit: gi|165933738|ref|YP_001650527.1| multidrug resistance protein B
1105113003044	Predicted GTPase [General function prediction only]; Region: ThdF; COG0486
1105113003045	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1105113003046	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1105113003047	G1 box; other site
1105113003048	GTP/Mg2+ binding site [chemical binding]; other site
1105113003049	Switch I region; other site
1105113003050	G2 box; other site
1105113003051	Switch II region; other site
1105113003052	G3 box; other site
1105113003053	G4 box; other site
1105113003054	G5 box; other site
1105113003055	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1105113003056	NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism]; Region: COG2902
1105113003057	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; smart00839
1105113003058	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
1105113003059	Helix-turn-helix domain; Region: HTH_25; pfam13413
1105113003060	Cell division protein ZapA (stimulator of FtsZ polymerization and Z-ring component) [Cell cycle control, cell division,    chromosome partitioning]; Region: zapA; COG3027
1105113003061	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1105113003062	metabolite-proton symporter; Region: 2A0106; TIGR00883
1105113003063	putative substrate translocation pore; other site
1105113003064	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1105113003065	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1105113003066	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1105113003067	4Fe-4S binding domain; Region: Fer4; cl02805
1105113003068	4Fe-4S binding domain; Region: Fer4; pfam00037
1105113003069	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1105113003070	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1105113003071	NADH dehydrogenase subunit G; Validated; Region: PRK09130
1105113003072	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1105113003073	catalytic loop [active]
1105113003074	iron binding site [ion binding]; other site
1105113003075	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1105113003076	MopB_Res_Cmplx1_Nad11: The second domain of the Nad11/75-kDa subunit of the NADH-quinone oxidoreductase/respiratory complex I/NADH dehydrogenase-1(NDH-1) of eukaryotes and the Nqo3/G subunit of alphaproteobacteria NDH-1. The NADH-quinone oxidoreductase...; Region: MopB_Res-Cmplx1_Nad11; cd02773
1105113003077	Domain of unknown function (DUF1982); Region: DUF1982; pfam09326
1105113003078	Predicted membrane protein [Function unknown]; Region: COG3671
1105113003079	aconitate hydratase; Validated; Region: PRK09277
1105113003080	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1105113003081	substrate binding site [chemical binding]; other site
1105113003082	ligand binding site [chemical binding]; other site
1105113003083	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1105113003084	substrate binding site [chemical binding]; other site
1105113003085	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK01474
1105113003086	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1105113003087	gamma subunit interface [polypeptide binding]; other site
1105113003088	epsilon subunit interface [polypeptide binding]; other site
1105113003089	LBP interface [polypeptide binding]; other site
1105113003090	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1105113003091	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1105113003092	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1105113003093	alpha subunit interaction interface [polypeptide binding]; other site
1105113003094	Walker A motif; other site
1105113003095	ATP binding site [chemical binding]; other site
1105113003096	Walker B motif; other site
1105113003097	inhibitor binding site; inhibition site
1105113003098	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1105113003099	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1105113003100	core domain interface [polypeptide binding]; other site
1105113003101	delta subunit interface [polypeptide binding]; other site
1105113003102	epsilon subunit interface [polypeptide binding]; other site
1105113003103	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1105113003104	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1105113003105	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1105113003106	beta subunit interaction interface [polypeptide binding]; other site
1105113003107	Walker A motif; other site
1105113003108	ATP binding site [chemical binding]; other site
1105113003109	Walker B motif; other site
1105113003110	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1105113003111	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1105113003112	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1105113003113	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1105113003114	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1105113003115	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1105113003116	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1105113003117	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1105113003118	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1105113003119	dinuclear metal binding motif [ion binding]; other site
1105113003120	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1105113003121	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1105113003122	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
1105113003123	Transglycosylase; Region: Transgly; pfam00912
1105113003124	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1105113003125	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1105113003126	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1105113003127	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1105113003128	FeS/SAM binding site; other site
1105113003129	TRAM domain; Region: TRAM; cl01282
1105113003130	potential frameshift: common BLAST hit: gi|91204878|ref|YP_537233.1| nucleotidyltransferase
1105113003131	Rickettsial palindromic element RPE1 domain; Region: RPE1; TIGR01045
1105113003132	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3807
1105113003133	Bacterial SH3 domain; Region: SH3_4; pfam06347
1105113003134	Bacterial SH3 domain; Region: SH3_4; pfam06347
1105113003135	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1105113003136	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1105113003137	TrkA-N domain; Region: TrkA_N; pfam02254
1105113003138	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1105113003139	Stress-induced morphogen (activity unknown) [Signal transduction mechanisms]; Region: BolA; COG0271
1105113003140	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113003141	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1105113003142	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105113003143	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105113003144	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105113003145	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105113003146	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105113003147	potential frameshift: common BLAST hit: gi|67459682|ref|YP_247306.1| cell surface antigen-like protein Sca13
1105113003148	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1105113003149	rRNA binding site [nucleotide binding]; other site
1105113003150	predicted 30S ribosome binding site; other site
1105113003151	Maf-like protein; Region: Maf; pfam02545
1105113003152	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1105113003153	active site
1105113003154	dimer interface [polypeptide binding]; other site
1105113003155	RNA polymerase-binding protein DksA; Region: dksA; TIGR02420
1105113003156	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1105113003157	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1105113003158	active site
1105113003159	DNA binding site [nucleotide binding]
1105113003160	Int/Topo IB signature motif; other site
1105113003161	Phasin protein; Region: Phasin_2; pfam09361
1105113003162	Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170
1105113003163	PLD-like domain; Region: PLDc_2; pfam13091
1105113003164	putative active site [active]
1105113003165	catalytic site [active]
1105113003166	potential frameshift: common BLAST hit: gi|157826281|ref|YP_001494001.1| Poly(3-hydroxyalkanoate) synthetase
1105113003167	potential frameshift: common BLAST hit: gi|67459690|ref|YP_247314.1| Poly(3-hydroxyalkanoate) synthetase
1105113003168	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1105113003169	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1105113003170	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1105113003171	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1105113003172	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1105113003173	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1105113003174	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1105113003175	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1105113003176	potential frameshift: common BLAST hit: gi|374319799|ref|YP_005066298.1| Putative acyltransferase
1105113003177	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1105113003178	active site
1105113003179	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1105113003180	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
1105113003181	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1105113003182	MPN+ (JAMM) motif; other site
1105113003183	Zinc-binding site [ion binding]; other site
1105113003184	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1105113003185	The members of this subfamily catalyze the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate (Und-P) molecule and N-acetylhexosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylhexosamine precursor; Region: GT_WbpL_WbcO_like; cd06854
1105113003186	Mg++ binding site [ion binding]; other site
1105113003187	putative catalytic motif [active]
1105113003188	putative substrate binding site [chemical binding]; other site
1105113003189	Protein of unknown function (DUF721); Region: DUF721; pfam05258
1105113003190	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1105113003191	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1105113003192	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1105113003193	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1105113003194	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1105113003195	HD domain; Region: HD_4; pfam13328
1105113003196	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1105113003197	synthetase active site [active]
1105113003198	NTP binding site [chemical binding]; other site
1105113003199	metal binding site [ion binding]; metal-binding site
1105113003200	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1105113003201	catalytic residues [active]
1105113003202	catalytic nucleophile [active]
1105113003203	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1105113003204	Presynaptic Site I dimer interface [polypeptide binding]; other site
1105113003205	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1105113003206	Synaptic Flat tetramer interface [polypeptide binding]; other site
1105113003207	Synaptic Site I dimer interface [polypeptide binding]; other site
1105113003208	DNA binding site [nucleotide binding]
1105113003209	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1105113003210	DNA-binding interface [nucleotide binding]; DNA binding site
1105113003211	putative transposase; Provisional; Region: PRK09857
1105113003212	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1105113003213	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1105113003214	Integrase core domain; Region: rve; pfam00665
1105113003215	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cl15270
1105113003216	HicB family; Region: HicB; pfam05534
1105113003217	ParA-like protein; Provisional; Region: PHA02518
1105113003218	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1105113003219	P-loop; other site
1105113003220	Magnesium ion binding site [ion binding]; other site