-- dump date   	20140620_042203
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
761193000001	Cre recombinase, C-terminal catalytic domain. Cre-like recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The bacteriophage P1 Cre...; Region: INT_Cre; cd00799
761193000002	DNA binding site [nucleotide binding]
761193000003	dimer interface [polypeptide binding]; other site
761193000004	active site
761193000005	Int/Topo IB signature motif; other site
761193000006	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193000007	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193000008	Cytochrome c; Region: Cytochrom_C; cl11414
761193000009	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
761193000010	ligand binding site [chemical binding]; other site
761193000011	metal binding site [ion binding]; metal-binding site
761193000012	Hydrogenase specific C-terminal endopeptidases, also called Hydrogen Maturation Proteases (H2MP). These enzymes belong to the peptidase family M52. Maturation of [FeNi] hydrogenases includes formation of the nickel metallocenter, proteolytic processing...; Region: H2MP; cl00477
761193000013	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
761193000014	nickel binding site [ion binding]; other site
761193000015	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
761193000016	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
761193000017	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
761193000018	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193000019	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193000020	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193000021	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193000022	Bacterial transcriptional repressor; Region: TetR; pfam13972
761193000023	Bifunctional nuclease; Region: DNase-RNase; pfam02577
761193000024	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
761193000025	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
761193000026	dimerization interface [polypeptide binding]; other site
761193000027	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
761193000028	ATP binding site [chemical binding]; other site
761193000029	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
761193000030	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
761193000031	HupF/HypC family; Region: HupF_HypC; pfam01455
761193000032	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
761193000033	CobN/Magnesium Chelatase; Region: CobN-Mg_chel; pfam02514
761193000034	Uncharacterized conserved protein (DUF2149); Region: DUF2149; pfam09919
761193000035	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
761193000036	High-affinity nickel-transport protein; Region: NicO; cl00964
761193000037	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
761193000038	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193000039	N-terminal plug; other site
761193000040	ligand-binding site [chemical binding]; other site
761193000041	Acylphosphatase; Region: Acylphosphatase; pfam00708
761193000042	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
761193000043	HypF finger; Region: zf-HYPF; pfam07503
761193000044	HypF finger; Region: zf-HYPF; pfam07503
761193000045	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
761193000046	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
761193000047	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
761193000048	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
761193000049	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
761193000050	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193000051	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
761193000052	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193000053	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193000054	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193000055	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193000056	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
761193000057	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193000058	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193000059	active site
761193000060	phosphorylation site [posttranslational modification]
761193000061	intermolecular recognition site; other site
761193000062	dimerization interface [polypeptide binding]; other site
761193000063	LytTr DNA-binding domain; Region: LytTR; smart00850
761193000064	Histidine kinase; Region: His_kinase; pfam06580
761193000065	Histidine kinase; Region: His_kinase; pfam06580
761193000066	Demethylmenaquinone methyltransferase; Region: Methyltransf_6; cl00480
761193000067	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
761193000068	Strictosidine synthase; Region: Str_synth; pfam03088
761193000069	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193000070	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193000071	putative substrate translocation pore; other site
761193000072	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
761193000073	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
761193000074	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
761193000075	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
761193000076	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
761193000077	classical (c) SDRs; Region: SDR_c; cd05233
761193000078	NAD(P) binding site [chemical binding]; other site
761193000079	active site
761193000080	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
761193000081	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193000082	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
761193000083	metal binding site [ion binding]; metal-binding site
761193000084	substrate binding pocket [chemical binding]; other site
761193000085	Glycosyl hydrolase family 10; Region: Glyco_10; smart00633
761193000086	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
761193000087	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193000088	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193000089	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193000090	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193000091	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193000092	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193000093	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
761193000094	Transcriptional regulator [Transcription]; Region: IclR; COG1414
761193000095	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
761193000096	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193000098	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
761193000099	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
761193000100	P-loop; other site
761193000101	Magnesium ion binding site [ion binding]; other site
761193000102	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
761193000103	Magnesium ion binding site [ion binding]; other site
761193000104	Initiator Replication protein; Region: Rep_3; pfam01051
761193000105	Prodigal; manually curated
761193000106	manually curated
761193000108	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
761193000109	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193000110	Walker A motif; other site
761193000111	ATP binding site [chemical binding]; other site
761193000112	Walker B motif; other site
761193000113	arginine finger; other site
761193000114	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
761193000115	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141
761193000116	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
761193000117	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
761193000118	active site residue [active]
761193000119	selenophosphate synthetase; Provisional; Region: PRK00943
761193000120	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
761193000121	dimerization interface [polypeptide binding]; other site
761193000122	putative ATP binding site [chemical binding]; other site
761193000123	Trehalose utilisation; Region: ThuA; pfam06283
761193000124	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
761193000125	active site
761193000126	catalytic triad [active]
761193000127	oxyanion hole [active]
761193000128	PAS domain S-box; Region: sensory_box; TIGR00229
761193000129	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193000130	putative active site [active]
761193000131	heme pocket [chemical binding]; other site
761193000132	PAS fold; Region: PAS_3; pfam08447
761193000133	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
761193000134	PAS domain S-box; Region: sensory_box; TIGR00229
761193000135	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193000136	putative active site [active]
761193000137	heme pocket [chemical binding]; other site
761193000138	PAS domain; Region: PAS_9; pfam13426
761193000139	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193000140	putative active site [active]
761193000141	heme pocket [chemical binding]; other site
761193000142	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193000143	PAS fold; Region: PAS_3; pfam08447
761193000144	putative active site [active]
761193000145	heme pocket [chemical binding]; other site
761193000146	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193000147	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193000148	dimer interface [polypeptide binding]; other site
761193000149	phosphorylation site [posttranslational modification]
761193000150	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193000151	ATP binding site [chemical binding]; other site
761193000152	Mg2+ binding site [ion binding]; other site
761193000153	G-X-G motif; other site
761193000154	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193000155	S-adenosylmethionine binding site [chemical binding]; other site
761193000156	Myo-inositol-1-phosphate synthase [Lipid metabolism]; Region: INO1; COG1260
761193000157	Myo-inositol-1-phosphate synthase; Region: NAD_binding_5; pfam07994
761193000158	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193000159	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
761193000160	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193000161	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
761193000162	Putative catalytic NodB homology domain of gellan lyase and similar proteins; Region: CE4_GLA_like_6s; cd10967
761193000163	putative active site [active]
761193000164	putative metal binding site [ion binding]; other site
761193000165	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
761193000166	Glycosyl hydrolase family 43, includes arabinoxylan arabinofuranohydrolase, beta-xylosidase, endo-1,4-beta-xylanase, alpha-L-arabinofuranosidase; Region: GH43_AXH_like; cd08990
761193000167	substrate binding site [chemical binding]; other site
761193000168	active site
761193000169	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
761193000170	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
761193000171	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; pfam00331
761193000172	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
761193000173	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193000174	N-terminal Early set domain associated with the catalytic domain of esterase; Region: E_set_Esterase_N; cd02858
761193000175	Putative esterase; Region: Esterase; pfam00756
761193000176	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193000177	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
761193000178	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193000179	Putative esterase; Region: Esterase; pfam00756
761193000180	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
761193000181	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
761193000182	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193000183	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
761193000184	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
761193000185	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193000186	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
761193000187	Putative esterase; Region: Esterase; pfam00756
761193000188	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193000189	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193000190	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
761193000191	Carboxylesterase family; Region: COesterase; pfam00135
761193000192	substrate binding pocket [chemical binding]; other site
761193000193	catalytic triad [active]
761193000194	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
761193000195	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_2; cd09001
761193000196	active site
761193000197	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
761193000198	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
761193000199	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
761193000200	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
761193000201	inhibitor binding site; inhibition site
761193000202	active site
761193000203	ParA-like protein; Provisional; Region: PHA02518
761193000204	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
761193000205	P-loop; other site
761193000206	Magnesium ion binding site [ion binding]; other site
761193000207	1,4-alpha-glucan-branching enzyme; Region: PLN02447
761193000208	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
761193000209	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
761193000210	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
761193000211	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193000212	non-specific DNA binding site [nucleotide binding]; other site
761193000213	salt bridge; other site
761193000214	sequence-specific DNA binding site [nucleotide binding]; other site
761193000215	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
761193000216	binding surface
761193000217	TPR motif; other site
761193000218	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
761193000219	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193000220	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193000221	Interdomain contacts; other site
761193000222	Cytokine receptor motif; other site
761193000223	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193000224	Interdomain contacts; other site
761193000225	Cytokine receptor motif; other site
761193000226	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193000227	Interdomain contacts; other site
761193000228	Cytokine receptor motif; other site
761193000229	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
761193000230	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
761193000231	active site
761193000232	substrate binding site [chemical binding]; other site
761193000233	Mg2+ binding site [ion binding]; other site
761193000234	AAA-like domain; Region: AAA_10; pfam12846
761193000235	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
761193000236	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
761193000237	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
761193000238	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
761193000239	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
761193000240	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
761193000241	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193000242	Walker A/P-loop; other site
761193000243	ATP binding site [chemical binding]; other site
761193000244	Q-loop/lid; other site
761193000245	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
761193000246	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
761193000247	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
761193000248	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
761193000249	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
761193000250	Conjugative transposon protein TraO; Region: TraO; pfam10626
761193000251	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
761193000252	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
761193000253	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
761193000254	catalytic residues [active]
761193000255	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
761193000256	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
761193000257	cofactor binding site; other site
761193000258	DNA binding site [nucleotide binding]
761193000259	substrate interaction site [chemical binding]; other site
761193000260	LlaMI restriction endonuclease; Region: RE_LlaMI; pfam09562
761193000261	COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); KEGG: csh:Closa_4233 conserved hypothetical membrane spanning protein; SPTR: Conserved hypothetical membrane spanning protein
761193000262	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
761193000263	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
761193000264	SEC-C motif; Region: SEC-C; pfam02810
761193000265	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
761193000266	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
761193000267	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
761193000268	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
761193000269	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
761193000270	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
761193000271	catalytic residues [active]
761193000272	catalytic nucleophile [active]
761193000273	hypothetical protein; Provisional; Region: PRK06153
761193000274	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
761193000275	ATP binding site [chemical binding]; other site
761193000276	substrate interface [chemical binding]; other site
761193000277	Bacterial multiubiquitin; Region: Bac_multiUb; pfam14452
761193000278	Piwi-like: PIWI domain. Domain found in proteins involved in RNA silencing. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs. The...; Region: Piwi-like; cl00628
761193000279	5' RNA guide strand anchoring site; other site
761193000280	active site
761193000281	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193000282	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193000283	non-specific DNA binding site [nucleotide binding]; other site
761193000284	salt bridge; other site
761193000285	sequence-specific DNA binding site [nucleotide binding]; other site
761193000286	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
761193000287	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
761193000288	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
761193000289	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
761193000290	active site
761193000291	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
761193000292	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
761193000293	Initiator Replication protein; Region: Rep_3; pfam01051
761193000294	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: GT1_like_1; cd04950
761193000295	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193000296	putative homodimer interface [polypeptide binding]; other site
761193000297	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
761193000298	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
761193000299	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
761193000300	NADP binding site [chemical binding]; other site
761193000301	active site
761193000302	putative substrate binding site [chemical binding]; other site
761193000303	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
761193000304	dimerization interface [polypeptide binding]; other site
761193000305	metal binding site [ion binding]; metal-binding site
761193000306	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193000307	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
761193000308	AP (apurinic/apyrimidinic) site pocket; other site
761193000309	Metal-binding active site; metal-binding site
761193000310	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
761193000311	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193000312	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193000313	HEAT repeats; Region: HEAT_2; pfam13646
761193000314	Cytochrome c; Region: Cytochrom_C; cl11414
761193000315	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
761193000316	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
761193000317	active site
761193000318	catalytic triad [active]
761193000319	oxyanion hole [active]
761193000320	Predicted acyl esterases [General function prediction only]; Region: COG2936
761193000321	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193000322	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
761193000323	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193000324	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
761193000325	active site
761193000326	DNA binding site [nucleotide binding]
761193000327	Int/Topo IB signature motif; other site
761193000328	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
761193000329	AAA domain; Region: AAA_14; pfam13173
761193000330	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
761193000331	active site
761193000332	DNA polymerase IV; Validated; Region: PRK02406
761193000333	DNA binding site [nucleotide binding]
761193000334	Protein of unknown function (DUF3318); Region: DUF3318; pfam11780
761193000335	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193000336	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193000337	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193000338	Uncharacterized protein conserved in bacteria [Function unknown]; Region: GguC; COG3802
761193000339	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
761193000340	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_4; cd07822
761193000341	putative hydrophobic ligand binding site [chemical binding]; other site
761193000342	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193000343	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193000344	ligand binding site [chemical binding]; other site
761193000345	flexible hinge region; other site
761193000346	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
761193000347	galactarate dehydratase; Region: galactar-dH20; TIGR03248
761193000348	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
761193000349	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
761193000350	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
761193000351	Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129
761193000352	dimer interface [polypeptide binding]; other site
761193000353	NADP binding site [chemical binding]; other site
761193000354	catalytic residues [active]
761193000355	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
761193000356	Cupin domain; Region: Cupin_2; pfam07883
761193000357	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193000358	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193000359	Initiator Replication protein; Region: Rep_3; pfam01051
761193000360	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
761193000361	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
761193000362	P-loop; other site
761193000363	Magnesium ion binding site [ion binding]; other site
761193000364	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
761193000365	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
761193000366	Magnesium ion binding site [ion binding]; other site
761193000367	Cytochrome c; Region: Cytochrom_C; cl11414
761193000368	Cytochrome c; Region: Cytochrom_C; pfam00034
761193000369	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
761193000370	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193000371	Predicted transporter component [General function prediction only]; Region: COG2391
761193000372	Sulphur transport; Region: Sulf_transp; pfam04143
761193000373	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
761193000374	Predicted transporter component [General function prediction only]; Region: COG2391
761193000375	Sulphur transport; Region: Sulf_transp; pfam04143
761193000376	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
761193000377	Competence-damaged protein; Region: CinA; pfam02464
761193000378	short chain dehydrogenase; Provisional; Region: PRK06701
761193000379	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193000380	NAD(P) binding site [chemical binding]; other site
761193000381	active site
761193000382	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
761193000383	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193000384	DnaA N-terminal domain; Region: DnaA_N; pfam11638
761193000385	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
761193000386	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193000387	Walker A motif; other site
761193000388	ATP binding site [chemical binding]; other site
761193000389	Walker B motif; other site
761193000390	arginine finger; other site
761193000391	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
761193000392	DnaA box-binding interface [nucleotide binding]; other site
761193000393	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
761193000394	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
761193000395	BON domain; Region: BON; pfam04972
761193000396	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193000397	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
761193000398	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
761193000399	putative ligand binding site [chemical binding]; other site
761193000400	putative NAD binding site [chemical binding]; other site
761193000401	catalytic site [active]
761193000402	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193000403	Coenzyme A binding pocket [chemical binding]; other site
761193000404	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
761193000405	VPS10 domain; Region: VPS10; smart00602
761193000406	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
761193000407	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
761193000408	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193000409	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193000410	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193000411	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193000412	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
761193000413	Walker A/P-loop; other site
761193000414	ATP binding site [chemical binding]; other site
761193000415	Q-loop/lid; other site
761193000416	ABC transporter signature motif; other site
761193000417	Walker B; other site
761193000418	D-loop; other site
761193000419	H-loop/switch region; other site
761193000420	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193000421	HEAT repeats; Region: HEAT_2; pfam13646
761193000422	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
761193000423	Cytochrome c; Region: Cytochrom_C; pfam00034
761193000424	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193000425	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193000426	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193000427	DNA binding residues [nucleotide binding]
761193000428	Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; Region: Prefoldin; cl09111
761193000429	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
761193000430	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193000431	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193000432	Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: LpqC; COG3509
761193000433	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193000434	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
761193000435	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
761193000436	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
761193000437	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193000438	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193000439	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
761193000440	dimer interface [polypeptide binding]; other site
761193000441	substrate binding site [chemical binding]; other site
761193000442	metal binding sites [ion binding]; metal-binding site
761193000443	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
761193000444	Heterodisulfide reductase, subunit B [Energy production and conversion]; Region: HdrB; COG2048
761193000445	Cysteine-rich domain; Region: CCG; pfam02754
761193000446	Cysteine-rich domain; Region: CCG; pfam02754
761193000447	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
761193000448	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
761193000449	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193000450	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193000451	active site
761193000452	phosphorylation site [posttranslational modification]
761193000453	intermolecular recognition site; other site
761193000454	dimerization interface [polypeptide binding]; other site
761193000455	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193000456	DNA binding site [nucleotide binding]
761193000457	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193000458	HAMP domain; Region: HAMP; pfam00672
761193000459	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193000460	dimer interface [polypeptide binding]; other site
761193000461	phosphorylation site [posttranslational modification]
761193000462	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193000463	ATP binding site [chemical binding]; other site
761193000464	Mg2+ binding site [ion binding]; other site
761193000465	G-X-G motif; other site
761193000466	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
761193000467	Ligand binding site; other site
761193000468	Putative Catalytic site; other site
761193000469	DXD motif; other site
761193000470	phosphoserine phosphatase SerB; Region: serB; TIGR00338
761193000471	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193000472	motif II; other site
761193000473	Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530
761193000474	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
761193000475	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
761193000476	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
761193000477	NHAD transporter family protein; Provisional; Region: PLN00137
761193000478	aldehyde dehydrogenase family 7 member; Region: PLN02315
761193000479	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
761193000480	tetrameric interface [polypeptide binding]; other site
761193000481	NAD binding site [chemical binding]; other site
761193000482	catalytic residues [active]
761193000483	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
761193000484	substrate binding site [chemical binding]; other site
761193000485	ATP binding site [chemical binding]; other site
761193000486	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
761193000487	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
761193000488	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
761193000489	Thermus thermophiles TTHB029 and similar proteins; Region: YdjC_TTHB029_like; cd10802
761193000490	putative active site [active]
761193000491	YdjC motif; other site
761193000492	Mg binding site [ion binding]; other site
761193000493	homodimer interface [polypeptide binding]; other site
761193000494	BNR repeat-like domain; Region: BNR_2; pfam13088
761193000495	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
761193000496	Asp-box motif; other site
761193000497	catalytic site [active]
761193000498	KEGG: see:SNSL254_A4376 hypothetical protein; SPTR:  uncharacterized protein
761193000499	Domain of unknown function (DUF4062); Region: DUF4062; pfam13271
761193000500	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
761193000501	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
761193000502	Secretory lipase; Region: LIP; pfam03583
761193000503	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
761193000504	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
761193000505	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
761193000506	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193000507	Walker A/P-loop; other site
761193000508	ATP binding site [chemical binding]; other site
761193000509	Q-loop/lid; other site
761193000510	ABC transporter signature motif; other site
761193000511	Walker B; other site
761193000512	D-loop; other site
761193000513	H-loop/switch region; other site
761193000514	ABC transporter; Region: ABC_tran_2; pfam12848
761193000515	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193000516	uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228
761193000517	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
761193000518	putative NADP binding site [chemical binding]; other site
761193000519	putative substrate binding site [chemical binding]; other site
761193000520	active site
761193000521	Bacterial protein of unknown function (DUF937); Region: DUF937; cl01528
761193000522	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193000523	ligand binding site [chemical binding]; other site
761193000524	DNA polymerase IV (family X) [DNA replication, recombination, and repair]; Region: POL4; COG1796
761193000525	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
761193000526	metal binding triad [ion binding]; metal-binding site
761193000527	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
761193000528	Histidinol phosphatase and related hydrolases of the PHP family [Amino acid transport and metabolism / General function prediction only]; Region: HIS2; COG1387
761193000529	active site
761193000530	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
761193000531	2TM domain; Region: 2TM; pfam13239
761193000532	2TM domain; Region: 2TM; pfam13239
761193000533	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
761193000534	ligand binding site [chemical binding]; other site
761193000535	active site
761193000536	UGI interface [polypeptide binding]; other site
761193000537	catalytic site [active]
761193000538	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
761193000539	Methyltransferase domain; Region: Methyltransf_24; pfam13578
761193000540	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
761193000541	MarR family; Region: MarR_2; pfam12802
761193000542	MarR family; Region: MarR_2; cl17246
761193000543	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193000544	putative substrate translocation pore; other site
761193000545	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
761193000546	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
761193000547	putative active site [active]
761193000548	substrate binding site [chemical binding]; other site
761193000549	putative cosubstrate binding site; other site
761193000550	catalytic site [active]
761193000551	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
761193000552	substrate binding site [chemical binding]; other site
761193000553	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
761193000554	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
761193000555	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
761193000556	GTP-binding protein YchF; Reviewed; Region: PRK09601
761193000557	YchF GTPase; Region: YchF; cd01900
761193000558	G1 box; other site
761193000559	GTP/Mg2+ binding site [chemical binding]; other site
761193000560	Switch I region; other site
761193000561	G2 box; other site
761193000562	Switch II region; other site
761193000563	G3 box; other site
761193000564	G4 box; other site
761193000565	G5 box; other site
761193000566	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
761193000567	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
761193000568	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
761193000569	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
761193000570	Protein of unknown function DUF58; Region: DUF58; pfam01882
761193000571	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
761193000572	Alpha amylase catalytic domain found in an uncharacterized protein family; Region: AmyAc_3; cd11349
761193000573	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
761193000574	active site
761193000575	catalytic site [active]
761193000576	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193000577	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193000578	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
761193000579	Subunit I/III interface [polypeptide binding]; other site
761193000580	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14609
761193000581	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
761193000582	phosphoserine phosphatase SerB; Region: serB; TIGR00338
761193000583	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
761193000584	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
761193000585	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
761193000586	ligand binding site [chemical binding]; other site
761193000587	NAD binding site [chemical binding]; other site
761193000588	tetramer interface [polypeptide binding]; other site
761193000589	catalytic site [active]
761193000590	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
761193000591	L-serine binding site [chemical binding]; other site
761193000592	ACT domain interface; other site
761193000593	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
761193000594	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
761193000595	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
761193000596	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
761193000597	active site
761193000598	metal binding site [ion binding]; metal-binding site
761193000599	DNA binding site [nucleotide binding]
761193000600	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
761193000601	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
761193000602	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193000603	Walker A/P-loop; other site
761193000604	ATP binding site [chemical binding]; other site
761193000605	Q-loop/lid; other site
761193000606	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193000607	ABC transporter signature motif; other site
761193000608	Walker B; other site
761193000609	D-loop; other site
761193000610	H-loop/switch region; other site
761193000611	conjugal transfer coupling protein TraG; Provisional; Region: PRK13880
761193000612	Uncharacterized conserved protein [Function unknown]; Region: COG1434
761193000613	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
761193000614	putative active site [active]
761193000615	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
761193000616	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193000617	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193000618	catalytic residues [active]
761193000619	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
761193000620	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193000621	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193000622	catalytic residues [active]
761193000623	ATP-dependent Clp protease adaptor protein ClpS; Region: ClpS; pfam02617
761193000624	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
761193000625	Na binding site [ion binding]; other site
761193000626	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193000627	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193000628	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193000629	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193000630	Uncharacterized conserved protein [Function unknown]; Region: COG1434
761193000631	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
761193000632	putative active site [active]
761193000633	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193000634	Coenzyme A binding pocket [chemical binding]; other site
761193000635	Pirin-related protein [General function prediction only]; Region: COG1741
761193000636	Pirin; Region: Pirin; pfam02678
761193000637	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
761193000638	BNR repeat-like domain; Region: BNR_2; pfam13088
761193000639	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
761193000640	Asp-box motif; other site
761193000641	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
761193000642	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
761193000643	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
761193000644	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
761193000645	6-phosphofructokinase; Provisional; Region: PRK03202
761193000646	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
761193000647	active site
761193000648	ADP/pyrophosphate binding site [chemical binding]; other site
761193000649	dimerization interface [polypeptide binding]; other site
761193000650	allosteric effector site; other site
761193000651	fructose-1,6-bisphosphate binding site; other site
761193000652	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193000653	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
761193000654	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193000655	N-terminal plug; other site
761193000656	ligand-binding site [chemical binding]; other site
761193000657	Uncharacterized conserved protein [Function unknown]; Region: COG4279
761193000658	SWIM zinc finger; Region: SWIM; pfam04434
761193000659	SNF2 Helicase protein; Region: DUF3670; pfam12419
761193000660	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
761193000661	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193000662	ATP binding site [chemical binding]; other site
761193000663	putative Mg++ binding site [ion binding]; other site
761193000664	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193000665	nucleotide binding region [chemical binding]; other site
761193000666	ATP-binding site [chemical binding]; other site
761193000667	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
761193000668	AAA-like domain; Region: AAA_10; pfam12846
761193000669	DNA sulfur modification protein DndD; Region: DNA_S_dndD; TIGR03185
761193000670	COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: dhd:Dhaf_1803 DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase; SPTR: DNA polymerase beta domain protein region
761193000671	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
761193000672	active site
761193000673	NTP binding site [chemical binding]; other site
761193000674	metal binding triad [ion binding]; metal-binding site
761193000675	antibiotic binding site [chemical binding]; other site
761193000676	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
761193000677	GxxExxY protein; Region: GxxExxY; TIGR04256
761193000678	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
761193000679	DNA methylase; Region: N6_N4_Mtase; pfam01555
761193000680	DNA methylase; Region: N6_N4_Mtase; pfam01555
761193000681	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193000682	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193000683	ligand binding site [chemical binding]; other site
761193000684	flexible hinge region; other site
761193000685	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
761193000686	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193000687	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
761193000688	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193000689	Interdomain contacts; other site
761193000690	Cytokine receptor motif; other site
761193000691	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
761193000692	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
761193000693	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
761193000694	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193000695	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193000696	ligand binding site [chemical binding]; other site
761193000697	flexible hinge region; other site
761193000698	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
761193000699	Cytochrome c; Region: Cytochrom_C; pfam00034
761193000700	nitrous-oxide reductase, Sec-dependent; Region: nitrous_NosZ_Gp; TIGR04246
761193000701	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
761193000702	NosL; Region: NosL; cl01769
761193000703	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
761193000704	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
761193000705	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
761193000706	Walker A/P-loop; other site
761193000707	ATP binding site [chemical binding]; other site
761193000708	Q-loop/lid; other site
761193000709	ABC transporter signature motif; other site
761193000710	Walker B; other site
761193000711	D-loop; other site
761193000712	H-loop/switch region; other site
761193000713	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
761193000714	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
761193000715	Fasciclin domain; Region: Fasciclin; pfam02469
761193000716	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
761193000717	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193000718	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193000719	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193000720	N-terminal plug; other site
761193000721	ligand-binding site [chemical binding]; other site
761193000722	BNR repeat-like domain; Region: BNR_2; pfam13088
761193000723	DinB family; Region: DinB; cl17821
761193000724	DinB superfamily; Region: DinB_2; pfam12867
761193000725	Glycosyl transferase family 1; Region: Glyco_trans_1_3; pfam13528
761193000726	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193000727	Uncharacterized conserved protein [Function unknown]; Region: COG1262
761193000728	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
761193000729	Protein of unknown function (DUF2805); Region: DUF2805; pfam10985
761193000730	Protein of unknown function (DUF429); Region: DUF429; cl12046
761193000731	Uncharacterized protein conserved in bacteria (DUF2256); Region: DUF2256; pfam10013
761193000732	Penicillin amidase; Region: Penicil_amidase; pfam01804
761193000733	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193000734	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193000735	active site
761193000736	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193000737	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193000738	S-adenosylmethionine binding site [chemical binding]; other site
761193000739	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
761193000740	active site
761193000741	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
761193000742	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
761193000743	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
761193000744	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
761193000745	glutaminase active site [active]
761193000746	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
761193000747	dimer interface [polypeptide binding]; other site
761193000748	active site
761193000749	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
761193000750	dimer interface [polypeptide binding]; other site
761193000751	active site
761193000752	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
761193000753	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH; cl00942
761193000754	aromatic arch; other site
761193000755	DCoH dimer interaction site [polypeptide binding]; other site
761193000756	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
761193000757	DCoH tetramer interaction site [polypeptide binding]; other site
761193000758	substrate binding site [chemical binding]; other site
761193000759	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
761193000760	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
761193000761	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
761193000762	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
761193000763	ATP synthase A chain; Region: ATP-synt_A; cl00413
761193000764	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
761193000765	Inward rectifier potassium channel; Region: IRK; pfam01007
761193000766	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
761193000767	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193000768	active site
761193000769	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
761193000770	active site
761193000771	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
761193000772	active site
761193000773	homodimer interface [polypeptide binding]; other site
761193000774	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
761193000775	GH3 auxin-responsive promoter; Region: GH3; pfam03321
761193000776	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
761193000777	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
761193000778	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
761193000779	metal-binding site [ion binding]
761193000780	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
761193000781	Soluble P-type ATPase [General function prediction only]; Region: COG4087
761193000782	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
761193000783	metal-binding site [ion binding]
761193000784	COGs: COG4409 Neuraminidase (sialidase); KEGG: sli:Slin_2629 glycosyl hydrolase; SPTR: Glycosyl hydrolase BNR repeat-containing protein
761193000785	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
761193000786	catalytic site [active]
761193000787	BNR repeat-like domain; Region: BNR_2; pfam13088
761193000788	Asp-box motif; other site
761193000789	Sulfatase; Region: Sulfatase; cl17466
761193000790	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193000791	Homeodomain-like domain; Region: HTH_23; pfam13384
761193000792	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193000793	Homeodomain-like domain; Region: HTH_32; pfam13565
761193000794	Winged helix-turn helix; Region: HTH_33; pfam13592
761193000795	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193000796	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193000797	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
761193000798	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
761193000799	active site residue [active]
761193000800	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
761193000801	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
761193000802	Substrate-binding site [chemical binding]; other site
761193000803	Substrate specificity [chemical binding]; other site
761193000804	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
761193000805	dimer interface [polypeptide binding]; other site
761193000806	putative radical transfer pathway; other site
761193000807	diiron center [ion binding]; other site
761193000808	tyrosyl radical; other site
761193000809	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
761193000810	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
761193000811	putative active site [active]
761193000812	putative metal binding site [ion binding]; other site
761193000813	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme D-Threonine Aldolase; Region: PLPDE_III_D-TA; cd06821
761193000814	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
761193000815	dimer interface [polypeptide binding]; other site
761193000816	active site
761193000817	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
761193000818	substrate binding site [chemical binding]; other site
761193000819	catalytic residue [active]
761193000820	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
761193000821	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
761193000822	putative dimer interface [polypeptide binding]; other site
761193000823	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193000824	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193000825	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193000826	DNA binding residues [nucleotide binding]
761193000827	Penicillin amidase; Region: Penicil_amidase; pfam01804
761193000828	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193000829	Cephalosporin acylase (CA) belongs to a family of beta-lactam acylases that includes penicillin G acylase (PGA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_CA; cd01936
761193000830	active site
761193000831	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193000832	Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059
761193000833	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
761193000834	acyl-activating enzyme (AAE) consensus motif; other site
761193000835	putative AMP binding site [chemical binding]; other site
761193000836	putative active site [active]
761193000837	putative CoA binding site [chemical binding]; other site
761193000838	Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418
761193000839	acyl-CoA dehydrogenase; Provisional; Region: PTZ00456
761193000840	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
761193000841	active site
761193000842	Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806
761193000843	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
761193000844	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
761193000845	hexamer interface [polypeptide binding]; other site
761193000846	ligand binding site [chemical binding]; other site
761193000847	putative active site [active]
761193000848	NAD(P) binding site [chemical binding]; other site
761193000849	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
761193000850	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193000851	putative DNA binding site [nucleotide binding]; other site
761193000852	putative Zn2+ binding site [ion binding]; other site
761193000853	AsnC family; Region: AsnC_trans_reg; pfam01037
761193000854	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase; Region: menD; TIGR00173
761193000855	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
761193000856	dimer interface [polypeptide binding]; other site
761193000857	tetramer interface [polypeptide binding]; other site
761193000858	PYR/PP interface [polypeptide binding]; other site
761193000859	TPP binding site [chemical binding]; other site
761193000860	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
761193000861	TPP-binding site; other site
761193000862	Methyltransferase domain; Region: Methyltransf_31; pfam13847
761193000863	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193000864	S-adenosylmethionine binding site [chemical binding]; other site
761193000865	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
761193000866	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193000867	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193000868	ligand binding site [chemical binding]; other site
761193000869	Methyltransferase domain; Region: Methyltransf_31; pfam13847
761193000870	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193000871	S-adenosylmethionine binding site [chemical binding]; other site
761193000872	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
761193000873	Fatty acid desaturase; Region: FA_desaturase; pfam00487
761193000874	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
761193000875	Di-iron ligands [ion binding]; other site
761193000876	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14185
761193000877	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
761193000878	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
761193000879	homodimer interface [polypeptide binding]; other site
761193000880	NADP binding site [chemical binding]; other site
761193000881	substrate binding site [chemical binding]; other site
761193000882	NAD-dependent deacetylase; Provisional; Region: PRK00481
761193000883	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
761193000884	NAD+ binding site [chemical binding]; other site
761193000885	substrate binding site [chemical binding]; other site
761193000886	Zn binding site [ion binding]; other site
761193000887	argininosuccinate synthase; Provisional; Region: PRK13820
761193000888	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
761193000889	Ligand Binding Site [chemical binding]; other site
761193000890	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
761193000891	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193000892	Coenzyme A binding pocket [chemical binding]; other site
761193000893	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
761193000894	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193000895	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193000896	Cytochrome c; Region: Cytochrom_C; cl11414
761193000897	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
761193000898	ligand binding site [chemical binding]; other site
761193000899	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
761193000900	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
761193000901	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193000902	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
761193000903	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
761193000904	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193000905	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193000906	catalytic residues [active]
761193000907	PspC domain; Region: PspC; pfam04024
761193000908	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193000909	Coenzyme A binding pocket [chemical binding]; other site
761193000910	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
761193000911	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
761193000912	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193000913	catalytic residue [active]
761193000914	bacillithiol biosynthesis deacetylase BshB1; Region: thiol_BshB1; TIGR04001
761193000915	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
761193000916	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193000917	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193000918	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
761193000919	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
761193000920	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193000921	TPR repeat; Region: TPR_11; pfam13414
761193000922	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193000923	binding surface
761193000924	TPR motif; other site
761193000925	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193000926	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193000927	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193000928	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193000929	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193000930	ligand binding site [chemical binding]; other site
761193000931	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
761193000932	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193000933	FeS/SAM binding site; other site
761193000934	Class I aldolases; Region: Aldolase_Class_I; cl17187
761193000935	catalytic residue [active]
761193000936	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
761193000937	FOG: CBS domain [General function prediction only]; Region: COG0517
761193000938	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
761193000939	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
761193000940	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193000941	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
761193000942	active site
761193000943	catalytic residues [active]
761193000944	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193000945	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
761193000946	active site
761193000947	Protein of unknown function (DUF1611); Region: DUF1611; pfam07755
761193000948	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193000949	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193000950	N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653
761193000951	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193000952	active site
761193000953	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193000954	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
761193000955	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193000956	putative DNA binding site [nucleotide binding]; other site
761193000957	putative Zn2+ binding site [ion binding]; other site
761193000958	AsnC family; Region: AsnC_trans_reg; pfam01037
761193000959	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193000960	Amidohydrolase; Region: Amidohydro_4; pfam13147
761193000961	active site
761193000962	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
761193000963	Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309
761193000964	active site
761193000965	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193000966	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193000967	Amidohydrolase; Region: Amidohydro_4; pfam13147
761193000968	active site
761193000969	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
761193000970	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
761193000971	COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: sli:Slin_0196 NmrA family protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NmrA family protein
761193000972	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
761193000973	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193000974	NAD(P) binding site [chemical binding]; other site
761193000975	active site
761193000976	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193000977	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193000978	Uncharacterized conserved protein [Function unknown]; Region: COG2308
761193000979	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
761193000980	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
761193000981	substrate binding site [chemical binding]; other site
761193000982	oxyanion hole (OAH) forming residues; other site
761193000983	trimer interface [polypeptide binding]; other site
761193000984	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
761193000985	putative catalytic site [active]
761193000986	putative metal binding site [ion binding]; other site
761193000987	putative phosphate binding site [ion binding]; other site
761193000988	recombination factor protein RarA; Reviewed; Region: PRK13342
761193000989	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193000990	Walker A motif; other site
761193000991	ATP binding site [chemical binding]; other site
761193000992	Walker B motif; other site
761193000993	arginine finger; other site
761193000994	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
761193000995	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193000996	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193000997	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193000998	DNA binding residues [nucleotide binding]
761193000999	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
761193001000	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
761193001001	active site
761193001002	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
761193001003	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
761193001004	putative ligand binding site [chemical binding]; other site
761193001005	COGs: COG0481 Membrane GTPase LepA; HAMAP: GTP-binding protein lepA; InterProIPR005225:IPR006297:IPR000795:IPR004161:IPR 000640:IPR013842; KEGG: dfe:Dfer_5632 GTP-binding protein LepA; PFAM: GTP-binding protein LepA, C-terminal; Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor 4; TIGRFAM: GTP-binding protein LepA; Small GTP-binding protein
761193001006	GTP-binding protein LepA; Provisional; Region: PRK05433
761193001007	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
761193001008	G1 box; other site
761193001009	putative GEF interaction site [polypeptide binding]; other site
761193001010	GTP/Mg2+ binding site [chemical binding]; other site
761193001011	Switch I region; other site
761193001012	G2 box; other site
761193001013	G3 box; other site
761193001014	Switch II region; other site
761193001015	G4 box; other site
761193001016	G5 box; other site
761193001017	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
761193001018	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
761193001019	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
761193001020	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193001021	putative active site [active]
761193001022	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
761193001023	E3 interaction surface; other site
761193001024	lipoyl attachment site [posttranslational modification]; other site
761193001025	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
761193001026	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
761193001027	E3 interaction surface; other site
761193001028	lipoyl attachment site [posttranslational modification]; other site
761193001029	e3 binding domain; Region: E3_binding; pfam02817
761193001030	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
761193001031	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
761193001032	active site
761193001033	HslU subunit interaction site [polypeptide binding]; other site
761193001034	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
761193001035	putative active site [active]
761193001036	catalytic residue [active]
761193001037	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193001038	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193001039	Lycopene cyclase protein; Region: Lycopene_cycl; pfam05834
761193001040	lycopene cyclase; Region: lycopene_cycl; TIGR01789
761193001041	beta-carotene 15,15'-monooxygenase, Brp/Blh family; Region: blh_monoox; TIGR03753
761193001042	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
761193001043	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
761193001044	active site
761193001045	HIGH motif; other site
761193001046	KMSKS motif; other site
761193001047	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
761193001048	tRNA binding surface [nucleotide binding]; other site
761193001049	anticodon binding site; other site
761193001050	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
761193001051	dimer interface [polypeptide binding]; other site
761193001052	putative tRNA-binding site [nucleotide binding]; other site
761193001053	Bacteriorhodopsin-like protein; Region: Bac_rhodopsin; smart01021
761193001054	Bacteriorhodopsin-like protein; Region: Bac_rhodopsin; pfam01036
761193001055	Predicted ATPases [General function prediction only]; Region: COG1106
761193001056	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193001057	Walker A/P-loop; other site
761193001058	ATP binding site [chemical binding]; other site
761193001059	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
761193001060	SmpB-tmRNA interface; other site
761193001061	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
761193001062	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193001063	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
761193001064	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
761193001065	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
761193001066	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
761193001067	Walker A/P-loop; other site
761193001068	ATP binding site [chemical binding]; other site
761193001069	Q-loop/lid; other site
761193001070	ABC transporter signature motif; other site
761193001071	Walker B; other site
761193001072	D-loop; other site
761193001073	H-loop/switch region; other site
761193001074	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
761193001075	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
761193001076	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
761193001077	Zn binding site [ion binding]; other site
761193001078	COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: dfe:Dfer_1167 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase domain protein TIM barrel
761193001079	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193001080	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
761193001081	AP (apurinic/apyrimidinic) site pocket; other site
761193001082	DNA interaction; other site
761193001083	Metal-binding active site; metal-binding site
761193001084	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193001085	Radical SAM superfamily; Region: Radical_SAM; pfam04055
761193001086	FeS/SAM binding site; other site
761193001087	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
761193001088	short chain dehydrogenase; Provisional; Region: PRK08628
761193001089	classical (c) SDRs; Region: SDR_c; cd05233
761193001090	NAD(P) binding site [chemical binding]; other site
761193001091	active site
761193001092	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
761193001093	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193001094	putative substrate translocation pore; other site
761193001095	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
761193001096	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
761193001097	NodB motif; other site
761193001098	active site
761193001099	catalytic site [active]
761193001100	metal binding site [ion binding]; metal-binding site
761193001101	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
761193001102	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
761193001103	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193001104	ATP binding site [chemical binding]; other site
761193001105	putative Mg++ binding site [ion binding]; other site
761193001106	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193001107	nucleotide binding region [chemical binding]; other site
761193001108	ATP-binding site [chemical binding]; other site
761193001109	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193001110	active site
761193001111	phosphorylation site [posttranslational modification]
761193001112	intermolecular recognition site; other site
761193001113	dimerization interface [polypeptide binding]; other site
761193001114	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
761193001115	cyclase homology domain; Region: CHD; cd07302
761193001116	nucleotidyl binding site; other site
761193001117	metal binding site [ion binding]; metal-binding site
761193001118	dimer interface [polypeptide binding]; other site
761193001119	Response regulator receiver domain; Region: Response_reg; pfam00072
761193001120	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193001121	active site
761193001122	phosphorylation site [posttranslational modification]
761193001123	intermolecular recognition site; other site
761193001124	dimerization interface [polypeptide binding]; other site
761193001125	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
761193001126	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
761193001127	dimer interface [polypeptide binding]; other site
761193001128	active site
761193001129	metal binding site [ion binding]; metal-binding site
761193001130	Predicted transcriptional regulators [Transcription]; Region: COG1733
761193001131	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
761193001132	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
761193001133	MarR family; Region: MarR; pfam01047
761193001134	COGs: COG1741 Pirin-related protein; InterPro IPR003829; KEGG: psn:Pedsa_0604 pirin domain protein; PFAM: Pirin, N-terminal; SPTR: Pirin family protein
761193001135	Pirin-related protein [General function prediction only]; Region: COG1741
761193001136	Pirin; Region: Pirin; pfam02678
761193001137	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
761193001138	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
761193001139	potential catalytic triad [active]
761193001140	conserved cys residue [active]
761193001141	GxxExxY protein; Region: GxxExxY; TIGR04256
761193001142	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
761193001143	Protein of unknown function, DUF481; Region: DUF481; cl01213
761193001144	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
761193001145	Protein of unknown function (DUF1211); Region: DUF1211; pfam06736
761193001146	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
761193001147	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
761193001148	HEAT repeats; Region: HEAT_2; pfam13646
761193001149	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
761193001150	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193001151	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193001152	ligand binding site [chemical binding]; other site
761193001153	flexible hinge region; other site
761193001154	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
761193001155	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193001156	dimer interface [polypeptide binding]; other site
761193001157	phosphorylation site [posttranslational modification]
761193001158	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193001159	ATP binding site [chemical binding]; other site
761193001160	Mg2+ binding site [ion binding]; other site
761193001161	G-X-G motif; other site
761193001162	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193001163	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001164	TPR motif; other site
761193001165	binding surface
761193001166	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193001167	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193001168	ATP binding site [chemical binding]; other site
761193001169	Mg2+ binding site [ion binding]; other site
761193001170	G-X-G motif; other site
761193001171	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193001172	F0F1 ATP synthase subunit B; Validated; Region: PRK06568
761193001173	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193001174	dimer interface [polypeptide binding]; other site
761193001175	phosphorylation site [posttranslational modification]
761193001176	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193001177	ATP binding site [chemical binding]; other site
761193001178	Mg2+ binding site [ion binding]; other site
761193001179	G-X-G motif; other site
761193001180	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
761193001181	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
761193001182	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193001183	dimer interface [polypeptide binding]; other site
761193001184	phosphorylation site [posttranslational modification]
761193001185	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193001186	ATP binding site [chemical binding]; other site
761193001187	Mg2+ binding site [ion binding]; other site
761193001188	G-X-G motif; other site
761193001189	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
761193001190	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193001191	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
761193001192	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
761193001193	DNA-binding site [nucleotide binding]; DNA binding site
761193001194	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193001195	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193001196	homodimer interface [polypeptide binding]; other site
761193001197	catalytic residue [active]
761193001198	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
761193001199	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
761193001200	putative metal binding site [ion binding]; other site
761193001201	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_ox_2; pfam12900
761193001202	Mycothiol maleylpyruvate isomerase N-terminal domain; Region: MDMPI_N; pfam11716
761193001203	DinB superfamily; Region: DinB_2; pfam12867
761193001204	Cupin domain; Region: Cupin_2; cl17218
761193001205	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
761193001206	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
761193001207	catalytic residue [active]
761193001208	Penicillin amidase; Region: Penicil_amidase; pfam01804
761193001209	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193001210	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193001211	active site
761193001212	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193001213	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
761193001214	active site
761193001215	catalytic triad [active]
761193001216	oxyanion hole [active]
761193001217	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193001218	HEAT repeats; Region: HEAT_2; pfam13646
761193001219	HEAT repeats; Region: HEAT_2; pfam13646
761193001220	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
761193001221	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
761193001222	Response regulator receiver domain; Region: Response_reg; pfam00072
761193001223	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193001224	active site
761193001225	phosphorylation site [posttranslational modification]
761193001226	intermolecular recognition site; other site
761193001227	dimerization interface [polypeptide binding]; other site
761193001228	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193001229	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193001230	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
761193001231	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193001232	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193001233	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193001234	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
761193001235	sulfite oxidase; Provisional; Region: PLN00177
761193001236	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
761193001237	Moco binding site; other site
761193001238	metal coordination site [ion binding]; other site
761193001239	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
761193001240	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
761193001241	classical (c) SDRs; Region: SDR_c; cd05233
761193001242	NAD(P) binding site [chemical binding]; other site
761193001243	active site
761193001244	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193001245	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193001246	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193001247	N-terminal plug; other site
761193001248	ligand-binding site [chemical binding]; other site
761193001249	Domain of unknown function (DUF3291); Region: DUF3291; pfam11695
761193001250	DNA polymerase III subunit epsilon; Validated; Region: PRK06195
761193001251	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
761193001252	active site
761193001253	catalytic site [active]
761193001254	substrate binding site [chemical binding]; other site
761193001255	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cl00038
761193001256	Dimer interface [polypeptide binding]; other site
761193001257	TM2 domain; Region: TM2; pfam05154
761193001258	Short C-terminal domain; Region: SHOCT; pfam09851
761193001259	Helix-turn-helix domain; Region: HTH_17; cl17695
761193001260	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
761193001261	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
761193001262	tandem repeat interface [polypeptide binding]; other site
761193001263	oligomer interface [polypeptide binding]; other site
761193001264	active site residues [active]
761193001265	ParB-like nuclease domain; Region: ParBc; cl02129
761193001266	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
761193001267	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
761193001268	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
761193001269	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
761193001270	Terminase-like family; Region: Terminase_6; pfam03237
761193001271	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cl00193
761193001272	TIGR02594 family protein; Region: TIGR02594
761193001273	Mu-like prophage protein [General function prediction only]; Region: COG3941
761193001274	UV radiation resistance protein and autophagy-related subunit 14; Region: Atg14; pfam10186
761193001275	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
761193001276	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193001277	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
761193001278	active site
761193001279	DNA binding site [nucleotide binding]
761193001280	Int/Topo IB signature motif; other site
761193001281	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
761193001282	Amidase; Region: Amidase; pfam01425
761193001283	Protein of unknown function (DUF3050); Region: DUF3050; pfam11251
761193001284	LytTr DNA-binding domain; Region: LytTR; pfam04397
761193001285	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
761193001286	active site
761193001287	Zn binding site [ion binding]; other site
761193001288	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193001289	Walker A motif; other site
761193001290	ATP binding site [chemical binding]; other site
761193001291	Walker B motif; other site
761193001292	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
761193001293	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
761193001294	active site
761193001295	Zn binding site [ion binding]; other site
761193001296	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system [Function unknown]; Region: COG4946
761193001297	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193001298	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193001299	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
761193001300	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
761193001301	Domain present in PSD-95, Dlg, and ZO-1/2; Region: PDZ; smart00228
761193001302	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
761193001303	Domain interface; other site
761193001304	Peptide binding site; other site
761193001305	Active site tetrad [active]
761193001306	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
761193001307	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
761193001308	intersubunit interface [polypeptide binding]; other site
761193001309	active site
761193001310	catalytic residue [active]
761193001311	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001312	binding surface
761193001313	TPR repeat; Region: TPR_11; pfam13414
761193001314	TPR motif; other site
761193001315	TPR repeat; Region: TPR_11; pfam13414
761193001316	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001317	binding surface
761193001318	TPR motif; other site
761193001319	TPR repeat; Region: TPR_11; pfam13414
761193001320	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001321	binding surface
761193001322	TPR motif; other site
761193001323	TPR repeat; Region: TPR_11; pfam13414
761193001324	TPR repeat; Region: TPR_11; pfam13414
761193001325	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001326	binding surface
761193001327	TPR motif; other site
761193001328	Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; cl01472
761193001329	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
761193001330	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
761193001331	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
761193001332	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193001333	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
761193001334	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
761193001335	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
761193001336	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
761193001337	Penicillinase repressor; Region: Pencillinase_R; pfam03965
761193001338	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
761193001339	homotrimer interaction site [polypeptide binding]; other site
761193001340	putative active site [active]
761193001341	SCP-2 sterol transfer family; Region: SCP2; pfam02036
761193001342	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
761193001343	DinB superfamily; Region: DinB_2; pfam12867
761193001344	Protein of unknown function (DUF419); Region: DUF419; pfam04237
761193001345	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Provisional; Region: PRK02048
761193001346	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
761193001347	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
761193001348	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
761193001349	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
761193001350	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
761193001351	S-adenosylmethionine synthetase; Validated; Region: PRK05250
761193001352	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
761193001353	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
761193001354	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
761193001355	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
761193001356	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
761193001357	FMN binding site [chemical binding]; other site
761193001358	active site
761193001359	catalytic residues [active]
761193001360	substrate binding site [chemical binding]; other site
761193001361	Protein of unknown function (DUF2891); Region: DUF2891; pfam11199
761193001362	Uncharacterized protein family UPF0560; Region: UPF0560; pfam10577
761193001363	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
761193001364	dimerization interface [polypeptide binding]; other site
761193001365	putative active cleft [active]
761193001366	Prodigal; manually curated
761193001367	COGs: COG1506 Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; KEGG: psl:Psta_0085 Dipeptidylaminopeptidase/acylaminoacyl-peptidase -like protein; SPTR:  uncharacterized protein
761193001368	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
761193001369	M20 Peptidases, Poly(aspartic acid) hydrolase-like proteins; Region: M20_PAAh_like; cd03896
761193001370	Peptidase family M20/M25/M40; Region: Peptidase_M20; pfam01546
761193001371	putative metal binding site [ion binding]; other site
761193001372	Uncharacterized conserved protein [Function unknown]; Region: COG3342
761193001373	Family of unknown function (DUF1028); Region: DUF1028; pfam06267
761193001374	TPR repeat; Region: TPR_11; pfam13414
761193001375	Caspase domain; Region: Peptidase_C14; pfam00656
761193001376	TPR repeat; Region: TPR_11; pfam13414
761193001377	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001378	binding surface
761193001379	TPR motif; other site
761193001380	TPR repeat; Region: TPR_11; pfam13414
761193001381	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001382	binding surface
761193001383	TPR motif; other site
761193001384	TPR repeat; Region: TPR_11; pfam13414
761193001385	TPR repeat; Region: TPR_11; pfam13414
761193001386	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001387	binding surface
761193001388	TPR motif; other site
761193001389	Tetratricopeptide repeat; Region: TPR_16; pfam13432
761193001390	TPR repeat; Region: TPR_11; pfam13414
761193001391	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001392	binding surface
761193001393	TPR motif; other site
761193001394	TPR repeat; Region: TPR_11; pfam13414
761193001395	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
761193001396	active site
761193001397	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193001398	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001399	TPR motif; other site
761193001400	binding surface
761193001401	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193001402	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193001403	binding surface
761193001404	TPR motif; other site
761193001405	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193001406	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193001407	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
761193001408	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193001409	ATP binding site [chemical binding]; other site
761193001410	Mg2+ binding site [ion binding]; other site
761193001411	G-X-G motif; other site
761193001412	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
761193001413	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
761193001414	putative catalytic residues [active]
761193001415	nucleotide binding site [chemical binding]; other site
761193001416	aspartate binding site [chemical binding]; other site
761193001417	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
761193001418	dimer interface [polypeptide binding]; other site
761193001419	putative threonine allosteric regulatory site; other site
761193001420	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
761193001421	putative threonine allosteric regulatory site; other site
761193001422	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
761193001423	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
761193001424	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193001425	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193001426	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193001427	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193001428	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193001429	NAD(P) binding site [chemical binding]; other site
761193001430	active site
761193001431	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193001432	Protein of unknown function (DUF1593); Region: DUF1593; pfam07632
761193001433	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193001434	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
761193001435	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193001436	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
761193001437	Transcriptional regulators [Transcription]; Region: PurR; COG1609
761193001438	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
761193001439	DNA binding site [nucleotide binding]
761193001440	domain linker motif; other site
761193001441	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
761193001442	dimerization interface [polypeptide binding]; other site
761193001443	ligand binding site [chemical binding]; other site
761193001444	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
761193001445	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
761193001446	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193001447	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193001448	DNA binding residues [nucleotide binding]
761193001449	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
761193001450	FecR protein; Region: FecR; pfam04773
761193001451	Secretin and TonB N terminus short domain; Region: STN; pfam07660
761193001452	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193001453	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193001454	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193001455	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193001456	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193001457	SusD family; Region: SusD; pfam07980
761193001458	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193001459	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
761193001460	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
761193001461	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193001462	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193001463	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193001464	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
761193001465	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193001466	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193001467	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193001468	SusD family; Region: SusD; pfam07980
761193001469	COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: sus:Acid_2628 mandelate racemase/muconate lactonizing protein; PFAM: Mandelate racemase/muconate lactonizing enzyme, C-terminal; Mandelate racemase/muconate lactonizing enzyme, N-terminal; SPTR: Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein
761193001470	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
761193001471	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193001472	active site pocket [active]
761193001473	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
761193001474	Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor...; Region: Ribosomal_L24e_L24; cl00909
761193001475	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
761193001476	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193001477	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
761193001478	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193001479	catalytic loop [active]
761193001480	iron binding site [ion binding]; other site
761193001481	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
761193001482	classical (c) SDRs; Region: SDR_c; cd05233
761193001483	NAD(P) binding site [chemical binding]; other site
761193001484	active site
761193001485	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
761193001486	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
761193001487	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
761193001488	tetramerization interface [polypeptide binding]; other site
761193001489	NAD(P) binding site [chemical binding]; other site
761193001490	catalytic residues [active]
761193001491	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
761193001492	Zn2+ binding site [ion binding]; other site
761193001493	Mg2+ binding site [ion binding]; other site
761193001494	hypothetical protein; Provisional; Region: PRK08296
761193001495	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
761193001496	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
761193001497	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
761193001498	Cytochrome P450; Region: p450; cl12078
761193001499	Bacterial transcriptional activator domain; Region: BTAD; smart01043
761193001500	Tetratricopeptide repeats; Region: TPR; smart00028
761193001501	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193001502	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193001503	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193001504	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
761193001505	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
761193001506	InterPro IPR004843; KEGG: zmn:Za10_1071 metallophosphoesterase; PFAM: Metallophosphoesterase; SPTR: Ser/Thr protein phosphatase
761193001507	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193001508	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193001509	active site
761193001510	metal binding site [ion binding]; metal-binding site
761193001511	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
761193001512	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193001513	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
761193001514	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193001515	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193001516	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
761193001517	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193001518	catalytic loop [active]
761193001519	iron binding site [ion binding]; other site
761193001520	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
761193001521	KEGG: sli:Slin_0356 hypothetical protein; SPTR:  uncharacterized protein
761193001522	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
761193001523	nudix motif; other site
761193001524	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
761193001525	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
761193001526	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
761193001527	active site
761193001528	catalytic tetrad [active]
761193001529	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193001530	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193001531	KEGG: sli:Slin_2860 hypothetical protein; SPTR:  uncharacterized protein
761193001532	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
761193001533	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
761193001534	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193001535	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
761193001536	Metal-binding active site; metal-binding site
761193001537	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
761193001538	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
761193001539	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
761193001540	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193001541	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
761193001542	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193001543	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193001544	putative substrate translocation pore; other site
761193001545	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
761193001546	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
761193001547	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193001548	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193001549	putative active site [active]
761193001550	Putative cyclase; Region: Cyclase; pfam04199
761193001551	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193001552	putative active site [active]
761193001553	COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: sli:Slin_1544 fumarylacetoacetate hydrolase; PFAM: Fumarylacetoacetase, C-terminal-like; SPTR: Fumarylacetoacetate (FAA) hydrolase
761193001554	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
761193001555	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
761193001556	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
761193001557	classical (c) SDRs; Region: SDR_c; cd05233
761193001558	NAD(P) binding site [chemical binding]; other site
761193001559	active site
761193001560	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
761193001561	histidinol dehydrogenase; Region: hisD; TIGR00069
761193001562	NAD binding site [chemical binding]; other site
761193001563	dimerization interface [polypeptide binding]; other site
761193001564	product binding site; other site
761193001565	substrate binding site [chemical binding]; other site
761193001566	zinc binding site [ion binding]; other site
761193001567	catalytic residues [active]
761193001568	hypothetical protein; Provisional; Region: PRK06847
761193001569	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
761193001570	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
761193001571	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193001572	N-terminal, non-catalytic, domain of BphC_JF8, (2,3-dihydroxybiphenyl 1,2-dioxygenase) from Bacillus sp. JF8 and similar proteins; Region: BphC-JF8_N_like; cd09013
761193001573	tetramer interface [polypeptide binding]; other site
761193001574	3,4-dihydroxyphenylacetate 2,3-dioxygenase; Region: HpaD; TIGR02295
761193001575	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
761193001576	active site
761193001577	metal binding site [ion binding]; metal-binding site
761193001578	Demethylmenaquinone methyltransferase; Region: Methyltransf_6; cl00480
761193001579	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193001580	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193001581	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
761193001582	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_4; cd04501
761193001583	active site
761193001584	catalytic triad [active]
761193001585	oxyanion hole [active]
761193001586	Transcriptional regulators [Transcription]; Region: PurR; COG1609
761193001587	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
761193001588	DNA binding site [nucleotide binding]
761193001589	domain linker motif; other site
761193001590	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
761193001591	ligand binding site [chemical binding]; other site
761193001592	dimerization interface [polypeptide binding]; other site
761193001593	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
761193001594	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
761193001595	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
761193001596	Protein of unknown function (DUF1446); Region: DUF1446; pfam07287
761193001597	Transposase IS200 like; Region: Y1_Tnp; cl00848
761193001598	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
761193001599	Citrate transporter; Region: CitMHS; pfam03600
761193001600	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
761193001601	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
761193001602	substrate binding pocket [chemical binding]; other site
761193001603	catalytic triad [active]
761193001604	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193001605	Protein of unknown function (DUF2680); Region: DUF2680; pfam10925
761193001606	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193001607	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
761193001608	Carboxylesterase family; Region: COesterase; pfam00135
761193001609	substrate binding pocket [chemical binding]; other site
761193001610	catalytic triad [active]
761193001611	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
761193001612	nudix motif; other site
761193001613	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
761193001614	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193001615	aldehyde reductase, extended (e) SDRs; Region: AR_SDR_e; cd05227
761193001616	NADP binding site [chemical binding]; other site
761193001617	putative substrate binding site [chemical binding]; other site
761193001618	active site
761193001619	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193001620	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193001621	ligand binding site [chemical binding]; other site
761193001622	flexible hinge region; other site
761193001623	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
761193001624	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
761193001625	NAD(P) binding site [chemical binding]; other site
761193001626	Fic family protein [Function unknown]; Region: COG3177
761193001627	Fic/DOC family; Region: Fic; pfam02661
761193001628	benzoate transport; Region: 2A0115; TIGR00895
761193001629	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292
761193001630	active site
761193001631	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
761193001632	four helix bundle protein; Region: TIGR02436
761193001633	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193001634	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193001635	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
761193001636	substrate binding site [chemical binding]; other site
761193001637	zinc-binding site [ion binding]; other site
761193001638	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08217
761193001639	17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs; Region: HSD10-like_SDR_c; cd05371
761193001640	NAD binding site [chemical binding]; other site
761193001641	homodimer interface [polypeptide binding]; other site
761193001642	homotetramer interface [polypeptide binding]; other site
761193001643	active site
761193001644	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_3; pfam13366
761193001645	feruloyl-CoA synthase; Reviewed; Region: PRK08180
761193001646	Feruloyl-CoA synthetase (FCS); Region: FCS; cd05921
761193001647	acyl-activating enzyme (AAE) consensus motif; other site
761193001648	putative AMP binding site [chemical binding]; other site
761193001649	putative active site [active]
761193001650	putative CoA binding site [chemical binding]; other site
761193001651	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
761193001652	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
761193001653	substrate binding site [chemical binding]; other site
761193001654	oxyanion hole (OAH) forming residues; other site
761193001655	trimer interface [polypeptide binding]; other site
761193001656	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193001657	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193001658	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193001659	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193001660	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193001661	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193001662	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193001663	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193001664	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193001665	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
761193001666	Protein of unknown function (DUF3237); Region: DUF3237; pfam11578
761193001667	hypothetical protein; Provisional; Region: PRK07538
761193001668	hypothetical protein; Provisional; Region: PRK07236
761193001669	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
761193001670	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193001671	putative substrate translocation pore; other site
761193001672	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
761193001673	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
761193001674	dimer interface [polypeptide binding]; other site
761193001675	active site
761193001676	AAA domain; Region: AAA_14; pfam13173
761193001677	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
761193001678	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
761193001679	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
761193001680	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
761193001681	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
761193001682	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
761193001683	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
761193001684	active site
761193001685	4-hydroxybenzoate 3-monooxygenase; Validated; Region: PRK08243
761193001686	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
761193001687	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
761193001688	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
761193001689	4-carboxymuconolactone decarboxylase; Region: decarb_PcaC; TIGR02425
761193001690	3-carboxy-cis,cis-muconate cycloisomerase; Provisional; Region: PRK09053
761193001691	prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597
761193001692	tetramer interface [polypeptide binding]; other site
761193001693	active site
761193001694	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
761193001695	active site
761193001696	Protocatechuate 3,4-dioxygenase (3,4-PCD) , beta subunit. 3,4-PCD catalyzes the oxidative ring cleavage of 3,4-dihydroxybenzoate to produce beta-carboxy-cis,cis-muconate. 3,4-PCDs are large aggregates of 12 protomers, each composed of an alpha- and...; Region: 3,4-PCD_beta; cd03464
761193001697	multimer interface [polypeptide binding]; other site
761193001698	heterodimer interface [polypeptide binding]; other site
761193001699	protocatechuate 3,4-dioxygenase, beta subunit; Region: protocat_beta; TIGR02422
761193001700	active site
761193001701	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
761193001702	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193001703	benzoate transport; Region: 2A0115; TIGR00895
761193001704	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193001705	putative substrate translocation pore; other site
761193001706	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
761193001707	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
761193001708	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193001709	catalytic residue [active]
761193001710	COGs: COG2133 Glucose/sorbosone dehydrogenase; InterPro IPR004155:IPR013427; KEGG: dfe:Dfer_4620 heme-binding protein; PFAM: PBS lyase HEAT-like repeat; SMART: PBS lyase HEAT-like repeat; SPTR: Heme-binding protein; TIGRFAM:  haem-binding region
761193001711	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193001712	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193001713	HEAT repeats; Region: HEAT_2; pfam13646
761193001714	Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin; Region: ARM; cd00020
761193001715	protein binding surface [polypeptide binding]; other site
761193001716	HEAT repeats; Region: HEAT_2; pfam13646
761193001717	Cytochrome c; Region: Cytochrom_C; pfam00034
761193001718	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
761193001719	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
761193001720	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
761193001721	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193001722	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193001723	Cytochrome c; Region: Cytochrom_C; cl11414
761193001724	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
761193001725	metal binding site [ion binding]; metal-binding site
761193001726	ligand binding site [chemical binding]; other site
761193001727	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
761193001728	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
761193001729	inhibitor-cofactor binding pocket; inhibition site
761193001730	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193001731	catalytic residue [active]
761193001732	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
761193001733	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
761193001734	ligand binding site [chemical binding]; other site
761193001735	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
761193001736	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
761193001737	active site
761193001738	substrate binding site [chemical binding]; other site
761193001739	metal binding site [ion binding]; metal-binding site
761193001740	Cupin-like domain; Region: Cupin_8; pfam13621
761193001741	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
761193001742	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
761193001743	dimer interface [polypeptide binding]; other site
761193001744	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193001745	Predicted transcriptional regulator [Transcription]; Region: COG2378
761193001746	HTH domain; Region: HTH_11; pfam08279
761193001747	WYL domain; Region: WYL; pfam13280
761193001748	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193001749	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193001750	AAA domain; Region: AAA_23; pfam13476
761193001751	AAA domain; Region: AAA_21; pfam13304
761193001752	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193001753	Walker B; other site
761193001754	D-loop; other site
761193001755	H-loop/switch region; other site
761193001756	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185
761193001757	AAA domain; Region: AAA_33; pfam13671
761193001758	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193001759	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
761193001760	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
761193001761	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
761193001762	Beta-lactamase; Region: Beta-lactamase; cl17358
761193001763	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193001764	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193001765	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193001766	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193001767	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
761193001768	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
761193001769	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
761193001770	structural tetrad; other site
761193001771	Phosphoesterase family; Region: Phosphoesterase; pfam04185
761193001772	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
761193001773	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193001774	N-terminal plug; other site
761193001775	ligand-binding site [chemical binding]; other site
761193001776	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
761193001777	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
761193001778	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
761193001779	Phosphoesterase family; Region: Phosphoesterase; pfam04185
761193001780	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193001781	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193001782	catalytic residue [active]
761193001783	Phosphotransferase enzyme family; Region: APH; pfam01636
761193001784	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
761193001785	active site
761193001786	ATP binding site [chemical binding]; other site
761193001787	substrate binding site [chemical binding]; other site
761193001788	Late embryogenesis abundant protein; Region: LEA_2; pfam03168
761193001789	Protein of unknown function (DUF3179); Region: DUF3179; pfam11376
761193001790	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
761193001791	active site
761193001792	PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398
761193001793	active site
761193001794	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
761193001795	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
761193001796	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193001797	This family is most closely related to the GT1 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide; Region: GT1_Bme6_like; cd03821
761193001798	putative ADP-binding pocket [chemical binding]; other site
761193001799	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193001800	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193001801	ligand binding site [chemical binding]; other site
761193001802	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
761193001803	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
761193001804	Histidine kinase; Region: His_kinase; pfam06580
761193001805	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193001806	ATP binding site [chemical binding]; other site
761193001807	Mg2+ binding site [ion binding]; other site
761193001808	G-X-G motif; other site
761193001809	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193001810	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193001811	active site
761193001812	phosphorylation site [posttranslational modification]
761193001813	intermolecular recognition site; other site
761193001814	dimerization interface [polypeptide binding]; other site
761193001815	LytTr DNA-binding domain; Region: LytTR; smart00850
761193001816	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193001817	putative active site [active]
761193001818	GMP synthase; Reviewed; Region: guaA; PRK00074
761193001819	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
761193001820	AMP/PPi binding site [chemical binding]; other site
761193001821	candidate oxyanion hole; other site
761193001822	catalytic triad [active]
761193001823	potential glutamine specificity residues [chemical binding]; other site
761193001824	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
761193001825	ATP Binding subdomain [chemical binding]; other site
761193001826	Ligand Binding sites [chemical binding]; other site
761193001827	Dimerization subdomain; other site
761193001828	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
761193001829	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
761193001830	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
761193001831	DDE superfamily endonuclease; Region: DDE_4_2; pfam13613
761193001832	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193001833	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
761193001834	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
761193001835	4Fe-4S binding domain; Region: Fer4; cl02805
761193001836	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
761193001837	NAD(P) binding site [chemical binding]; other site
761193001838	carboxylate-amine ligase; Provisional; Region: PRK13515
761193001839	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
761193001840	ATP-grasp domain; Region: ATP-grasp_4; cl17255
761193001841	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4947
761193001842	Putative esterase; Region: Esterase; pfam00756
761193001843	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
761193001844	active site
761193001845	hydrophilic channel; other site
761193001846	dimerization interface [polypeptide binding]; other site
761193001847	catalytic residues [active]
761193001848	active site lid [active]
761193001849	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
761193001850	homotrimer interaction site [polypeptide binding]; other site
761193001851	putative active site [active]
761193001852	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
761193001853	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
761193001854	dimer interface [polypeptide binding]; other site
761193001855	active site
761193001856	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
761193001857	active site
761193001858	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
761193001859	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193001860	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4947
761193001861	putative transporter; Provisional; Region: PRK10484
761193001862	Na(+)- and Cl(-)-dependent choline cotransporter CHT and related proteins; solute-binding domain; Region: SLC5sbd_CHT; cd11474
761193001863	Na binding site [ion binding]; other site
761193001864	putative glycosylation site [posttranslational modification]; other site
761193001865	putative glycosylation site [posttranslational modification]; other site
761193001866	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
761193001867	nudix motif; other site
761193001868	Repair protein; Region: Repair_PSII; pfam04536
761193001869	Repair protein; Region: Repair_PSII; pfam04536
761193001870	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
761193001871	GH3 auxin-responsive promoter; Region: GH3; pfam03321
761193001872	Glycerophosphodiester phosphodiesterase domain of putative Silicibacter pomeroyi glycerophosphodiester phosphodiesterase and similar proteins; Region: GDPD_SpGDE_like; cd08567
761193001873	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
761193001874	active site
761193001875	catalytic site [active]
761193001876	metal binding site [ion binding]; metal-binding site
761193001877	Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119
761193001878	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
761193001879	active site
761193001880	catalytic residues [active]
761193001881	metal binding site [ion binding]; metal-binding site
761193001882	choline dehydrogenase; Validated; Region: PRK02106
761193001883	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193001884	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
761193001885	DNA-binding site [nucleotide binding]; DNA binding site
761193001886	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
761193001887	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
761193001888	Walker A/P-loop; other site
761193001889	ATP binding site [chemical binding]; other site
761193001890	Q-loop/lid; other site
761193001891	ABC transporter signature motif; other site
761193001892	Walker B; other site
761193001893	D-loop; other site
761193001894	H-loop/switch region; other site
761193001895	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
761193001896	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
761193001897	active site
761193001898	catalytic site [active]
761193001899	substrate binding site [chemical binding]; other site
761193001900	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193001901	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193001902	FtsX-like permease family; Region: FtsX; pfam02687
761193001903	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193001904	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
761193001905	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193001906	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193001907	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193001908	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193001909	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193001910	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193001911	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
761193001912	Periplasmic binding proteins specific to rhizopines; Region: PBP1_rhizopine_binding_like; cd06301
761193001913	putative ligand binding site [chemical binding]; other site
761193001914	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
761193001915	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
761193001916	TM-ABC transporter signature motif; other site
761193001917	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
761193001918	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
761193001919	Walker A/P-loop; other site
761193001920	ATP binding site [chemical binding]; other site
761193001921	Q-loop/lid; other site
761193001922	ABC transporter signature motif; other site
761193001923	Walker B; other site
761193001924	D-loop; other site
761193001925	H-loop/switch region; other site
761193001926	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
761193001927	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
761193001928	putative ligand binding site [chemical binding]; other site
761193001929	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
761193001930	active site
761193001931	NTP binding site [chemical binding]; other site
761193001932	metal binding triad [ion binding]; metal-binding site
761193001933	antibiotic binding site [chemical binding]; other site
761193001934	HEPN domain; Region: HEPN; cl00824
761193001935	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193001936	Walker A motif; other site
761193001937	ATP binding site [chemical binding]; other site
761193001938	Walker B motif; other site
761193001939	arginine finger; other site
761193001940	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
761193001941	Predicted NTPase (NACHT family) [Signal transduction mechanisms]; Region: COG5635
761193001942	Homeodomain-like domain; Region: HTH_23; pfam13384
761193001943	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193001944	Homeodomain-like domain; Region: HTH_32; pfam13565
761193001945	Winged helix-turn helix; Region: HTH_33; pfam13592
761193001946	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193001947	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193001948	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193001949	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193001950	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193001951	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193001952	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
761193001953	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
761193001954	active site
761193001955	catalytic residues [active]
761193001956	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193001957	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193001958	Putative SAM-dependent RNA methyltransferase; Region: Methyltrn_RNA_2; cl00827
761193001959	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
761193001960	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
761193001961	AP (apurinic/apyrimidinic) site pocket; other site
761193001962	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193001963	DNA interaction; other site
761193001964	Metal-binding active site; metal-binding site
761193001965	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193001966	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193001967	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193001968	dimer interface [polypeptide binding]; other site
761193001969	phosphorylation site [posttranslational modification]
761193001970	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193001971	ATP binding site [chemical binding]; other site
761193001972	Mg2+ binding site [ion binding]; other site
761193001973	G-X-G motif; other site
761193001974	Response regulator receiver domain; Region: Response_reg; pfam00072
761193001975	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193001976	active site
761193001977	phosphorylation site [posttranslational modification]
761193001978	intermolecular recognition site; other site
761193001979	dimerization interface [polypeptide binding]; other site
761193001980	FIST N domain; Region: FIST; pfam08495
761193001981	FIST C domain; Region: FIST_C; pfam10442
761193001982	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
761193001983	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
761193001984	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
761193001985	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
761193001986	N- and C-terminal domain interface [polypeptide binding]; other site
761193001987	active site
761193001988	catalytic site [active]
761193001989	metal binding site [ion binding]; metal-binding site
761193001990	carbohydrate binding site [chemical binding]; other site
761193001991	ATP binding site [chemical binding]; other site
761193001992	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
761193001993	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
761193001994	AsnC family; Region: AsnC_trans_reg; pfam01037
761193001995	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
761193001996	active site
761193001997	ornithine aminotransferase; Region: Orn_aminotrans; TIGR01885
761193001998	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
761193001999	inhibitor-cofactor binding pocket; inhibition site
761193002000	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193002001	catalytic residue [active]
761193002002	cryptochrome, DASH family; Region: crypto_DASH; TIGR02765
761193002003	DNA photolyase; Region: DNA_photolyase; pfam00875
761193002004	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
761193002005	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193002006	putative metal binding site [ion binding]; other site
761193002007	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
761193002008	G1 box; other site
761193002009	GTP/Mg2+ binding site [chemical binding]; other site
761193002010	Switch I region; other site
761193002011	G2 box; other site
761193002012	G3 box; other site
761193002013	Switch II region; other site
761193002014	G4 box; other site
761193002015	G5 box; other site
761193002016	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
761193002017	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
761193002018	putative substrate binding site [chemical binding]; other site
761193002019	putative ATP binding site [chemical binding]; other site
761193002020	4Fe-4S binding domain; Region: Fer4; pfam00037
761193002021	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
761193002022	4Fe-4S binding domain; Region: Fer4; pfam00037
761193002023	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
761193002024	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
761193002025	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
761193002026	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
761193002027	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
761193002028	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193002029	S-adenosylmethionine binding site [chemical binding]; other site
761193002030	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
761193002031	N-acetyl-D-glucosamine binding site [chemical binding]; other site
761193002032	catalytic residue [active]
761193002033	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193002034	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193002035	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193002036	Protein of unknown function (DUF3109); Region: DUF3109; pfam11307
761193002037	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
761193002038	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
761193002039	DNA binding site [nucleotide binding]
761193002040	active site
761193002041	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193002042	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193002043	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193002044	ligand binding site [chemical binding]; other site
761193002045	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
761193002046	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
761193002047	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
761193002048	nucleotide binding site/active site [active]
761193002049	HIT family signature motif; other site
761193002050	catalytic residue [active]
761193002051	elongation factor G; Reviewed; Region: PRK12739
761193002052	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
761193002053	G1 box; other site
761193002054	putative GEF interaction site [polypeptide binding]; other site
761193002055	GTP/Mg2+ binding site [chemical binding]; other site
761193002056	Switch I region; other site
761193002057	G2 box; other site
761193002058	G3 box; other site
761193002059	Switch II region; other site
761193002060	G4 box; other site
761193002061	G5 box; other site
761193002062	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
761193002063	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
761193002064	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
761193002065	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
761193002066	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193002067	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
761193002068	DNA binding residues [nucleotide binding]
761193002069	dimerization interface [polypeptide binding]; other site
761193002070	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193002071	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193002072	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193002073	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193002074	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193002075	Sulfatase; Region: Sulfatase; pfam00884
761193002076	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
761193002077	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
761193002078	COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: sli:Slin_6289 sulfatase; PFAM: Sulfatase; PRIAM: Cerebroside-sulfatase; SPTR: Sulfatase
761193002079	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193002080	Sulfatase; Region: Sulfatase; pfam00884
761193002081	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
761193002082	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
761193002083	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
761193002084	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
761193002085	putative chaperone; Provisional; Region: PRK11678
761193002086	nucleotide binding site [chemical binding]; other site
761193002087	putative NEF/HSP70 interaction site [polypeptide binding]; other site
761193002088	SBD interface [polypeptide binding]; other site
761193002089	Outer membrane efflux protein; Region: OEP; pfam02321
761193002090	Outer membrane efflux protein; Region: OEP; pfam02321
761193002091	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
761193002092	Protein export membrane protein; Region: SecD_SecF; cl14618
761193002093	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193002094	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193002095	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193002096	Protein of unknown function (DUF3570); Region: DUF3570; pfam12094
761193002097	Domain of unknown function (DUF4266); Region: DUF4266; pfam14086
761193002098	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
761193002099	ApbE family; Region: ApbE; pfam02424
761193002100	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
761193002101	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193002102	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
761193002103	iron-sulfur cluster [ion binding]; other site
761193002104	[2Fe-2S] cluster binding site [ion binding]; other site
761193002105	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193002106	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193002107	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193002108	Histidine kinase; Region: His_kinase; pfam06580
761193002109	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
761193002110	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193002111	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193002112	active site
761193002113	phosphorylation site [posttranslational modification]
761193002114	intermolecular recognition site; other site
761193002115	dimerization interface [polypeptide binding]; other site
761193002116	LytTr DNA-binding domain; Region: LytTR; smart00850
761193002117	transcription termination factor Rho; Provisional; Region: PRK12678
761193002118	ribonuclease E; Reviewed; Region: rne; PRK10811
761193002119	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
761193002120	active site
761193002121	Zn binding site [ion binding]; other site
761193002122	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
761193002123	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
761193002124	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
761193002125	putative active site [active]
761193002126	catalytic triad [active]
761193002127	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
761193002128	Surface antigen; Region: Bac_surface_Ag; pfam01103
761193002129	Family of unknown function (DUF490); Region: DUF490; pfam04357
761193002130	pyruvate dehydrogenase subunit beta; Validated; Region: PRK09212
761193002131	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
761193002132	alpha subunit interface [polypeptide binding]; other site
761193002133	TPP binding site [chemical binding]; other site
761193002134	heterodimer interface [polypeptide binding]; other site
761193002135	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
761193002136	Cytochrome P450; Region: p450; pfam00067
761193002137	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
761193002138	hypothetical protein; Validated; Region: PRK09039
761193002139	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
761193002140	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193002141	ligand binding site [chemical binding]; other site
761193002142	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
761193002143	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
761193002144	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
761193002145	protein binding site [polypeptide binding]; other site
761193002146	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
761193002147	Catalytic dyad [active]
761193002148	short chain dehydrogenase; Provisional; Region: PRK06057
761193002149	classical (c) SDRs; Region: SDR_c; cd05233
761193002150	NAD(P) binding site [chemical binding]; other site
761193002151	active site
761193002152	COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR010168; KEGG: sli:Slin_4957 amidohydrolase; PFAM: Peptidase M20; Peptidase M20, dimerisation; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Amidohydrolase; TIGRFAM: Peptidase M20D, amidohydrolase
761193002153	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
761193002154	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
761193002155	metal binding site [ion binding]; metal-binding site
761193002156	dimer interface [polypeptide binding]; other site
761193002157	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
761193002158	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
761193002159	active site
761193002160	(T/H)XGH motif; other site
761193002161	acyl carrier protein; Provisional; Region: acpP; PRK00982
761193002162	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
761193002163	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
761193002164	dimer interface [polypeptide binding]; other site
761193002165	active site
761193002166	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
761193002167	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
761193002168	dimerization interface [polypeptide binding]; other site
761193002169	active site
761193002170	metal binding site [ion binding]; metal-binding site
761193002171	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
761193002172	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
761193002173	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
761193002174	Uncharacterized conserved protein [Function unknown]; Region: COG5276
761193002175	Uncharacterized conserved protein [Function unknown]; Region: COG5276
761193002176	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
761193002177	Part of AAA domain; Region: AAA_19; pfam13245
761193002178	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
761193002179	AAA domain; Region: AAA_12; pfam13087
761193002180	Protein of unknown function (DUF2400); Region: DUF2400; pfam09674
761193002181	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
761193002182	putative active site [active]
761193002183	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
761193002184	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
761193002185	VanZ like family; Region: VanZ; cl01971
761193002186	tartrate dehydrogenase; Region: TTC; TIGR02089
761193002187	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
761193002188	GxxExxY protein; Region: GxxExxY; TIGR04256
761193002189	(R)-citramalate synthase; Provisional; Region: PRK09389
761193002190	Leptospira interrogans citramalate synthase (CMS) and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_CMS; cd07945
761193002191	active site
761193002192	catalytic residues [active]
761193002193	metal binding site [ion binding]; metal-binding site
761193002194	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
761193002195	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
761193002196	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
761193002197	substrate binding site [chemical binding]; other site
761193002198	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
761193002199	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
761193002200	substrate binding site [chemical binding]; other site
761193002201	ligand binding site [chemical binding]; other site
761193002202	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193002203	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193002204	Protein of unknown function DUF86; Region: DUF86; cl01031
761193002205	COGs: COG1724 periplasmic or secreted lipoprotein; InterPro IPR012933; KEGG: tye:THEYE_A1079 hypothetical protein; PFAM: YcfA-like; SPTR: Conserved domain protein
761193002206	Predicted RNA binding protein (dsRBD-like fold), HicA family    [General function prediction only]; Region: COG1724
761193002207	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
761193002208	threonine dehydratase; Validated; Region: PRK08639
761193002209	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
761193002210	tetramer interface [polypeptide binding]; other site
761193002211	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193002212	catalytic residue [active]
761193002213	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
761193002214	putative Ile/Val binding site [chemical binding]; other site
761193002215	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
761193002216	ketol-acid reductoisomerase; Region: ilvC; TIGR00465
761193002217	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
761193002218	Methyltransferase domain; Region: Methyltransf_23; pfam13489
761193002219	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193002220	S-adenosylmethionine binding site [chemical binding]; other site
761193002221	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
761193002222	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
761193002223	putative valine binding site [chemical binding]; other site
761193002224	dimer interface [polypeptide binding]; other site
761193002225	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
761193002226	Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028
761193002227	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
761193002228	PYR/PP interface [polypeptide binding]; other site
761193002229	dimer interface [polypeptide binding]; other site
761193002230	TPP binding site [chemical binding]; other site
761193002231	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
761193002232	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
761193002233	TPP-binding site [chemical binding]; other site
761193002234	dimer interface [polypeptide binding]; other site
761193002235	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
761193002236	Uncharacterized conserved protein [Function unknown]; Region: COG4095
761193002237	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
761193002238	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
761193002239	domain interfaces; other site
761193002240	active site
761193002241	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193002242	primosomal protein N' Region: priA; TIGR00595
761193002243	ATP binding site [chemical binding]; other site
761193002244	putative Mg++ binding site [ion binding]; other site
761193002245	helicase superfamily c-terminal domain; Region: HELICc; smart00490
761193002246	Cna protein B-type domain; Region: Cna_B; pfam05738
761193002247	hypothetical protein; Provisional; Region: PRK07101
761193002248	substrate-cofactor binding pocket; other site
761193002249	para-aminobenzoate synthase component I; Validated; Region: PRK07093
761193002250	Surface antigen; Region: Bac_surface_Ag; pfam01103
761193002251	GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; Region: GT_2_like_a; cd02522
761193002252	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
761193002253	Probable Catalytic site; other site
761193002254	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193002255	non-specific DNA binding site [nucleotide binding]; other site
761193002256	salt bridge; other site
761193002257	sequence-specific DNA binding site [nucleotide binding]; other site
761193002258	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
761193002259	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193002260	S-adenosylmethionine binding site [chemical binding]; other site
761193002261	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
761193002262	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193002263	active site
761193002264	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
761193002265	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
761193002266	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193002267	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193002268	ligand binding site [chemical binding]; other site
761193002269	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
761193002270	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
761193002271	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
761193002272	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
761193002273	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
761193002274	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193002275	UDP-galactopyranose mutase; Region: GLF; pfam03275
761193002276	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
761193002277	4Fe-4S binding domain; Region: Fer4_2; pfam12797
761193002278	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
761193002279	Mg-chelatase subunit ChlI [Coenzyme metabolism]; Region: ChlI; COG1239
761193002280	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
761193002281	TPR repeat; Region: TPR_11; pfam13414
761193002282	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002283	binding surface
761193002284	TPR motif; other site
761193002285	TPR repeat; Region: TPR_11; pfam13414
761193002286	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002287	binding surface
761193002288	TPR motif; other site
761193002289	TPR repeat; Region: TPR_11; pfam13414
761193002290	TPR repeat; Region: TPR_11; pfam13414
761193002291	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002292	binding surface
761193002293	TPR motif; other site
761193002294	EamA-like transporter family; Region: EamA; pfam00892
761193002295	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
761193002296	EamA-like transporter family; Region: EamA; pfam00892
761193002297	Uncharacterized protein conserved in bacteria (DUF2309); Region: DUF2309; pfam10070
761193002298	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
761193002299	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
761193002300	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
761193002301	putative catalytic site [active]
761193002302	putative metal binding site [ion binding]; other site
761193002303	putative phosphate binding site [ion binding]; other site
761193002304	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193002305	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193002306	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193002307	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
761193002308	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
761193002309	inhibitor site; inhibition site
761193002310	active site
761193002311	dimer interface [polypeptide binding]; other site
761193002312	catalytic residue [active]
761193002313	COGs: COG4639 kinase; KEGG: rer:RER_24970 polynucleotide kinase; PRIAM: Polynucleotide 5'-hydroxyl-kinase; SPTR:  phage polynucleotide kinase
761193002314	polynucleotide kinase; Provisional; Region: pseT; PHA02530
761193002315	AAA domain; Region: AAA_17; pfam13207
761193002316	HAD superfamily, subfamily IIIB (Acid phosphatase); Region: Acid_phosphat_B; cl17236
761193002317	Sulfatase; Region: Sulfatase; cl17466
761193002318	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193002319	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193002320	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
761193002321	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193002322	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193002323	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193002324	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193002325	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193002326	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193002327	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
761193002328	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193002329	NAD(P) binding site [chemical binding]; other site
761193002330	active site
761193002331	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
761193002332	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193002333	catalytic loop [active]
761193002334	iron binding site [ion binding]; other site
761193002335	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
761193002336	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193002337	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
761193002338	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
761193002339	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193002340	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193002341	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
761193002342	active site
761193002343	catalytic site [active]
761193002344	substrate binding site [chemical binding]; other site
761193002345	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
761193002346	active site
761193002347	catalytic residues [active]
761193002348	metal binding site [ion binding]; metal-binding site
761193002349	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
761193002350	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
761193002351	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
761193002352	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
761193002353	protein binding site [polypeptide binding]; other site
761193002354	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
761193002355	protein binding site [polypeptide binding]; other site
761193002356	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
761193002357	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
761193002358	putative NAD(P) binding site [chemical binding]; other site
761193002359	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193002360	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193002361	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193002362	Protein of unknown function (DUF2905); Region: DUF2905; pfam11146
761193002363	nucleoside transporter; Region: 2A0110; TIGR00889
761193002364	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
761193002365	putative active site [active]
761193002366	putative catalytic site [active]
761193002367	putative DNA binding site [nucleotide binding]; other site
761193002368	putative phosphate binding site [ion binding]; other site
761193002369	metal binding site A [ion binding]; metal-binding site
761193002370	putative AP binding site [nucleotide binding]; other site
761193002371	putative metal binding site B [ion binding]; other site
761193002372	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002373	binding surface
761193002374	TPR motif; other site
761193002375	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002376	binding surface
761193002377	TPR motif; other site
761193002378	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
761193002379	TPR motif; other site
761193002380	binding surface
761193002381	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002382	binding surface
761193002383	TPR motif; other site
761193002384	TPR repeat; Region: TPR_11; pfam13414
761193002385	TPR repeat; Region: TPR_11; pfam13414
761193002386	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002387	binding surface
761193002388	TPR motif; other site
761193002389	Domain of unknown function (DUF4292); Region: DUF4292; pfam14125
761193002390	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
761193002391	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193002392	similar to 3-methyl-2-oxobutanoatehydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: dfe:Dfer_3776 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase
761193002393	similar to pseudouridine synthase; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family; KEGG: dfe:Dfer_3777 conserved hypothetical protein, membrane; SPTR:  uncharacterized protein
761193002394	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
761193002395	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193002396	ATP binding site [chemical binding]; other site
761193002397	Mg2+ binding site [ion binding]; other site
761193002398	G-X-G motif; other site
761193002399	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
761193002400	ATP binding site [chemical binding]; other site
761193002401	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
761193002402	Rhomboid family; Region: Rhomboid; pfam01694
761193002403	Rhomboid family; Region: Rhomboid; cl11446
761193002404	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
761193002405	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
761193002406	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
761193002407	TPP-binding site; other site
761193002408	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
761193002409	PYR/PP interface [polypeptide binding]; other site
761193002410	dimer interface [polypeptide binding]; other site
761193002411	TPP binding site [chemical binding]; other site
761193002412	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
761193002413	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
761193002414	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
761193002415	Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; cl01472
761193002416	Transcriptional regulators [Transcription]; Region: MarR; COG1846
761193002417	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
761193002418	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193002419	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
761193002420	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193002421	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193002422	Reovirus sigma C capsid protein; Region: Reo_sigmaC; pfam04582
761193002423	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
761193002424	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193002425	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193002426	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
761193002427	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
761193002428	putative active site; other site
761193002429	catalytic triad [active]
761193002430	putative dimer interface [polypeptide binding]; other site
761193002431	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
761193002432	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
761193002433	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
761193002434	metal binding site [ion binding]; metal-binding site
761193002435	Response regulator receiver domain; Region: Response_reg; pfam00072
761193002436	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193002437	active site
761193002438	phosphorylation site [posttranslational modification]
761193002439	intermolecular recognition site; other site
761193002440	dimerization interface [polypeptide binding]; other site
761193002441	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193002442	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
761193002443	Walker A motif; other site
761193002444	ATP binding site [chemical binding]; other site
761193002445	Walker B motif; other site
761193002446	arginine finger; other site
761193002447	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
761193002448	active site
761193002449	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
761193002450	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
761193002451	Zn2+ binding site [ion binding]; other site
761193002452	Mg2+ binding site [ion binding]; other site
761193002453	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
761193002454	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
761193002455	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
761193002456	trimer interface [polypeptide binding]; other site
761193002457	active site
761193002458	UDP-GlcNAc binding site [chemical binding]; other site
761193002459	lipid binding site [chemical binding]; lipid-binding site
761193002460	bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed; Region: PRK13188
761193002461	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
761193002462	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
761193002463	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
761193002464	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
761193002465	active site
761193002466	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
761193002467	Putative catalytic NodB homology domain of gellan lyase and similar proteins; Region: CE4_GLA_like_6s; cd10967
761193002468	putative active site [active]
761193002469	putative metal binding site [ion binding]; other site
761193002470	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193002471	HEAT repeats; Region: HEAT_2; pfam13646
761193002472	HEAT repeats; Region: HEAT_2; pfam13646
761193002473	HEAT repeats; Region: HEAT_2; pfam13646
761193002474	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
761193002475	Cytochrome c; Region: Cytochrom_C; pfam00034
761193002476	cysteine synthase B; Region: cysM; TIGR01138
761193002477	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
761193002478	dimer interface [polypeptide binding]; other site
761193002479	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193002480	catalytic residue [active]
761193002481	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
761193002482	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
761193002483	GldH lipoprotein; Region: GldH_lipo; pfam14109
761193002484	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
761193002485	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
761193002486	nucleoside/Zn binding site; other site
761193002487	dimer interface [polypeptide binding]; other site
761193002488	catalytic motif [active]
761193002489	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cl17196
761193002490	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
761193002491	putative glycosyl transferase; Provisional; Region: PRK10307
761193002492	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
761193002493	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
761193002494	CoenzymeA binding site [chemical binding]; other site
761193002495	subunit interaction site [polypeptide binding]; other site
761193002496	PHB binding site; other site
761193002497	Cellulose synthase catalytic subunit A2 (CESA2) is a catalytic subunit or a catalytic subunit substitute of the cellulose synthase complex; Region: CESA_CaSu_A2; cd06437
761193002498	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
761193002499	DXD motif; other site
761193002500	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
761193002501	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193002502	LytTr DNA-binding domain; Region: LytTR; smart00850
761193002503	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
761193002504	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193002505	Walker A motif; other site
761193002506	ATP binding site [chemical binding]; other site
761193002507	Walker B motif; other site
761193002508	arginine finger; other site
761193002509	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
761193002510	InterPro IPR000601; KEGG: sli:Slin_5230 PKD domain containing protein; PFAM: PKD; SMART: PKD; SPTR: PKD domain containing protein
761193002511	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193002512	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193002513	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193002514	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193002515	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193002516	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193002517	putative substrate translocation pore; other site
761193002518	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193002519	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193002520	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12745
761193002521	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193002522	NAD(P) binding site [chemical binding]; other site
761193002523	active site
761193002524	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
761193002525	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
761193002526	active site
761193002527	FMN binding site [chemical binding]; other site
761193002528	substrate binding site [chemical binding]; other site
761193002529	putative catalytic residue [active]
761193002530	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
761193002531	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
761193002532	fructuronate transporter; Provisional; Region: PRK10034; cl15264
761193002533	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
761193002534	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
761193002535	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
761193002536	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
761193002537	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; cl09156
761193002538	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193002539	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193002540	SusD family; Region: SusD; pfam07980
761193002541	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193002542	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193002543	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193002544	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193002545	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
761193002546	FecR protein; Region: FecR; pfam04773
761193002547	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
761193002548	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193002549	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193002550	DNA binding residues [nucleotide binding]
761193002551	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
761193002552	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193002553	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
761193002554	active site
761193002555	catalytic triad [active]
761193002556	oxyanion hole [active]
761193002557	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193002558	HEAT repeats; Region: HEAT_2; pfam13646
761193002559	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193002560	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
761193002561	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
761193002562	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193002563	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193002564	Secretin and TonB N terminus short domain; Region: STN; pfam07660
761193002565	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193002566	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193002567	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193002568	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193002569	FecR protein; Region: FecR; pfam04773
761193002570	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193002571	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193002572	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193002573	DNA binding residues [nucleotide binding]
761193002574	EcsC protein family; Region: EcsC; pfam12787
761193002575	hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234
761193002576	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
761193002577	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
761193002578	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193002579	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
761193002580	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
761193002581	substrate-cofactor binding pocket; other site
761193002582	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193002583	catalytic residue [active]
761193002584	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193002585	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193002586	NAD(P) binding site [chemical binding]; other site
761193002587	active site
761193002588	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193002589	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193002590	active site
761193002591	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
761193002592	Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219
761193002593	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
761193002594	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193002595	motif II; other site
761193002596	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
761193002597	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
761193002598	substrate binding site [chemical binding]; other site
761193002599	ATP binding site [chemical binding]; other site
761193002600	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
761193002601	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193002602	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193002603	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193002604	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
761193002605	Protein export membrane protein; Region: SecD_SecF; cl14618
761193002606	Bacteroidetes-specific putative membrane protein; Region: Bac_Flav_fam_1; TIGR03519
761193002607	HEPN domain; Region: HEPN; cl00824
761193002608	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
761193002609	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
761193002610	Walker A/P-loop; other site
761193002611	ATP binding site [chemical binding]; other site
761193002612	Q-loop/lid; other site
761193002613	ABC transporter signature motif; other site
761193002614	Walker B; other site
761193002615	D-loop; other site
761193002616	H-loop/switch region; other site
761193002617	thymidine kinase; Provisional; Region: PRK04296
761193002618	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
761193002619	Plasmid stabilisation system protein; Region: Plasmid_stabil; cl17483
761193002620	Mycoplasma protein of unknown function, DUF285; Region: DUF285; pfam03382
761193002621	bacterial surface protein 26-residue repeat; Region: Liste_lipo_26; TIGR02167
761193002622	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
761193002623	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193002624	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193002625	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193002626	hypothetical protein; Provisional; Region: PRK08201
761193002627	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_1; cd05678
761193002628	putative metal binding site [ion binding]; other site
761193002629	putative dimer interface [polypeptide binding]; other site
761193002630	Predicted membrane protein [Function unknown]; Region: COG2246
761193002631	GtrA-like protein; Region: GtrA; pfam04138
761193002632	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
761193002633	copper transport repressor, CopY/TcrY family; Region: CopY_TcrY; TIGR02698
761193002634	Penicillinase repressor; Region: Pencillinase_R; pfam03965
761193002635	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
761193002636	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
761193002637	putative catalytic cysteine [active]
761193002638	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_2; cd06239
761193002639	putative active site [active]
761193002640	Zn binding site [ion binding]; other site
761193002641	Predicted membrane protein [Function unknown]; Region: COG4270
761193002642	pantoate--beta-alanine ligase; Region: panC; TIGR00018
761193002643	Pantoate-beta-alanine ligase; Region: PanC; cd00560
761193002644	active site
761193002645	ATP-binding site [chemical binding]; other site
761193002646	pantoate-binding site; other site
761193002647	HXXH motif; other site
761193002648	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
761193002649	tetramerization interface [polypeptide binding]; other site
761193002650	active site
761193002651	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
761193002652	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
761193002653	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
761193002654	active site
761193002655	nucleotide binding site [chemical binding]; other site
761193002656	HIGH motif; other site
761193002657	KMSKS motif; other site
761193002658	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
761193002659	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
761193002660	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193002661	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193002662	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
761193002663	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
761193002664	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
761193002665	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193002666	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193002667	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193002668	non-specific DNA binding site [nucleotide binding]; other site
761193002669	salt bridge; other site
761193002670	sequence-specific DNA binding site [nucleotide binding]; other site
761193002671	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193002672	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
761193002673	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193002674	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
761193002675	COGs: COG3415 Transposase and inactivated derivatives; InterPro IPR001523; KEGG: sli:Slin_5275 transposase; PFAM: Paired box protein, N-terminal; SPTR: Transposase and inactivated derivatives-like protein; manually curated
761193002676	Homeodomain-like domain; Region: HTH_23; pfam13384
761193002677	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193002678	Homeodomain-like domain; Region: HTH_32; pfam13565
761193002679	Winged helix-turn helix; Region: HTH_33; pfam13592
761193002680	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193002681	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193002682	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
761193002683	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
761193002684	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
761193002685	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
761193002686	putative active site [active]
761193002687	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193002688	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193002689	Walker A/P-loop; other site
761193002690	ATP binding site [chemical binding]; other site
761193002691	Q-loop/lid; other site
761193002692	ABC transporter signature motif; other site
761193002693	Walker B; other site
761193002694	D-loop; other site
761193002695	H-loop/switch region; other site
761193002696	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
761193002697	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193002698	MoxR-like ATPases [General function prediction only]; Region: COG0714
761193002699	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193002700	Walker A motif; other site
761193002701	ATP binding site [chemical binding]; other site
761193002702	Walker B motif; other site
761193002703	arginine finger; other site
761193002704	Transcriptional regulator [Transcription]; Region: LysR; COG0583
761193002705	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
761193002706	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
761193002707	putative dimerization interface [polypeptide binding]; other site
761193002708	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
761193002709	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
761193002710	cofactor binding site; other site
761193002711	DNA binding site [nucleotide binding]
761193002712	substrate interaction site [chemical binding]; other site
761193002713	COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: mtt:Ftrac_2199 beta-lactamase; PFAM: Beta-lactamase-related; SPTR: Beta-lactamase
761193002714	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193002715	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193002716	Thermus thermophiles TTHB029 and similar proteins; Region: YdjC_TTHB029_like; cd10802
761193002717	putative active site [active]
761193002718	YdjC motif; other site
761193002719	Mg binding site [ion binding]; other site
761193002720	homodimer interface [polypeptide binding]; other site
761193002721	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193002722	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193002723	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
761193002724	Probable Catalytic site; other site
761193002725	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
761193002726	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193002727	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
761193002728	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
761193002729	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
761193002730	beta subunit interaction interface [polypeptide binding]; other site
761193002731	Walker A motif; other site
761193002732	ATP binding site [chemical binding]; other site
761193002733	Walker B motif; other site
761193002734	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
761193002735	Methyltransferase domain; Region: Methyltransf_24; pfam13578
761193002736	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
761193002737	core domain interface [polypeptide binding]; other site
761193002738	delta subunit interface [polypeptide binding]; other site
761193002739	epsilon subunit interface [polypeptide binding]; other site
761193002740	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
761193002741	KEGG: pdi:BDI_0151 hypothetical protein; SPTR:  uncharacterized protein
761193002742	Glycosyltransferase like family 2; Region: Glyco_tranf_2_2; pfam10111
761193002743	Prodigal; manually curated
761193002744	COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: lby:Lbys_1269 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver region; Transcription regulator LuxR, C-terminal; SPTR: Two component transcriptional regulator, LuxR family
761193002745	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193002746	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193002747	active site
761193002748	phosphorylation site [posttranslational modification]
761193002749	intermolecular recognition site; other site
761193002750	dimerization interface [polypeptide binding]; other site
761193002751	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
761193002752	dimerization interface [polypeptide binding]; other site
761193002753	DNA binding residues [nucleotide binding]
761193002754	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
761193002755	FAD binding domain; Region: FAD_binding_4; pfam01565
761193002756	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
761193002757	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
761193002758	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193002759	S-adenosylmethionine binding site [chemical binding]; other site
761193002760	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193002761	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
761193002762	putative NAD(P) binding site [chemical binding]; other site
761193002763	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193002764	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193002765	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193002766	DNA binding residues [nucleotide binding]
761193002767	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
761193002768	FAD binding domain; Region: FAD_binding_4; pfam01565
761193002769	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
761193002770	16S rRNA methyltransferase B; Provisional; Region: PRK14902
761193002771	RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223
761193002772	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
761193002773	quinohemoprotein amine dehydrogenase, alpha subunit; Region: QH_alpha; TIGR03908
761193002774	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
761193002775	Subgroup of sulfite oxidase (SO) family molybdopterin binding domains that contains conserved dimerization domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate...; Region: SO_family_Moco_dimer; cd02110
761193002776	Moco binding site; other site
761193002777	metal coordination site [ion binding]; other site
761193002778	dimerization interface [polypeptide binding]; other site
761193002779	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193002780	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
761193002781	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193002782	catalytic residue [active]
761193002783	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
761193002784	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193002785	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193002786	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
761193002787	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193002788	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193002789	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193002790	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
761193002791	Protein export membrane protein; Region: SecD_SecF; cl14618
761193002792	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
761193002793	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
761193002794	SelR domain; Region: SelR; pfam01641
761193002795	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4634
761193002796	Protein of unknown function (DUF433); Region: DUF433; pfam04255
761193002797	Protein of unknown function (DUF1684); Region: DUF1684; pfam07920
761193002798	PAS domain; Region: PAS_9; pfam13426
761193002799	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193002800	putative active site [active]
761193002801	heme pocket [chemical binding]; other site
761193002802	PAS domain; Region: PAS_9; pfam13426
761193002803	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193002804	putative active site [active]
761193002805	heme pocket [chemical binding]; other site
761193002806	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
761193002807	GAF domain; Region: GAF; pfam01590
761193002808	PAS domain S-box; Region: sensory_box; TIGR00229
761193002809	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193002810	putative active site [active]
761193002811	heme pocket [chemical binding]; other site
761193002812	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193002813	PAS domain; Region: PAS; smart00091
761193002814	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193002815	PAS fold; Region: PAS_3; pfam08447
761193002816	putative active site [active]
761193002817	heme pocket [chemical binding]; other site
761193002818	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193002819	dimer interface [polypeptide binding]; other site
761193002820	phosphorylation site [posttranslational modification]
761193002821	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193002822	ATP binding site [chemical binding]; other site
761193002823	Mg2+ binding site [ion binding]; other site
761193002824	G-X-G motif; other site
761193002825	Response regulator receiver domain; Region: Response_reg; pfam00072
761193002826	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193002827	active site
761193002828	phosphorylation site [posttranslational modification]
761193002829	intermolecular recognition site; other site
761193002830	dimerization interface [polypeptide binding]; other site
761193002831	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193002832	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193002833	active site
761193002834	phosphorylation site [posttranslational modification]
761193002835	intermolecular recognition site; other site
761193002836	dimerization interface [polypeptide binding]; other site
761193002837	PAS domain S-box; Region: sensory_box; TIGR00229
761193002838	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193002839	putative active site [active]
761193002840	heme pocket [chemical binding]; other site
761193002841	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193002842	dimer interface [polypeptide binding]; other site
761193002843	phosphorylation site [posttranslational modification]
761193002844	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193002845	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193002846	active site
761193002847	phosphorylation site [posttranslational modification]
761193002848	intermolecular recognition site; other site
761193002849	dimerization interface [polypeptide binding]; other site
761193002850	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
761193002851	DNA-binding site [nucleotide binding]; DNA binding site
761193002852	Transcriptional regulators [Transcription]; Region: PurR; COG1609
761193002853	Ligand-binding domain of a transcription repressor, FucR, which functions as a molecular sensor of L-fucose availability; Region: PBP1_FucR_like; cd06276
761193002854	putative dimerization interface [polypeptide binding]; other site
761193002855	putative ligand binding site [chemical binding]; other site
761193002856	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
761193002857	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
761193002858	putative ATP binding site [chemical binding]; other site
761193002859	putative substrate interface [chemical binding]; other site
761193002860	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193002861	active site
761193002862	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; cl17496
761193002863	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193002864	Coenzyme A binding pocket [chemical binding]; other site
761193002865	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
761193002866	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
761193002867	Predicted permeases [General function prediction only]; Region: COG0679
761193002868	Secretin and TonB N terminus short domain; Region: STN; pfam07660
761193002869	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193002870	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193002871	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193002872	N-terminal plug; other site
761193002873	ligand-binding site [chemical binding]; other site
761193002874	FecR protein; Region: FecR; pfam04773
761193002875	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
761193002876	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193002877	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193002878	DNA binding residues [nucleotide binding]
761193002879	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
761193002880	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
761193002881	putative active site [active]
761193002882	Putative esterase; Region: Esterase; pfam00756
761193002883	S-formylglutathione hydrolase; Region: PLN02442
761193002884	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
761193002885	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
761193002886	Metal-binding active site; metal-binding site
761193002887	Protein of unknown function (DUF433); Region: DUF433; pfam04255
761193002888	Protein of unknown function (DUF1501); Region: DUF1501; pfam07394
761193002889	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193002890	Protein of unknown function (DUF1549); Region: PSCyt2; pfam07583
761193002891	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
761193002892	Protein of unknown function (DUF1553); Region: PSD1; pfam07587
761193002893	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193002894	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193002895	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193002896	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193002897	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
761193002898	putative active site [active]
761193002899	homotetrameric interface [polypeptide binding]; other site
761193002900	metal binding site [ion binding]; metal-binding site
761193002901	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193002902	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
761193002903	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
761193002904	dimerization interface [polypeptide binding]; other site
761193002905	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193002906	dimer interface [polypeptide binding]; other site
761193002907	phosphorylation site [posttranslational modification]
761193002908	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193002909	ATP binding site [chemical binding]; other site
761193002910	Mg2+ binding site [ion binding]; other site
761193002911	G-X-G motif; other site
761193002912	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
761193002913	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
761193002914	acyl-activating enzyme (AAE) consensus motif; other site
761193002915	AMP binding site [chemical binding]; other site
761193002916	active site
761193002917	CoA binding site [chemical binding]; other site
761193002918	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
761193002919	iron-sulfur cluster [ion binding]; other site
761193002920	[2Fe-2S] cluster binding site [ion binding]; other site
761193002921	CotH protein; Region: CotH; pfam08757
761193002922	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193002923	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
761193002924	AMP nucleosidase; Provisional; Region: PRK07115
761193002925	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002926	binding surface
761193002927	TPR motif; other site
761193002928	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
761193002929	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002930	binding surface
761193002931	TPR motif; other site
761193002932	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002933	binding surface
761193002934	TPR motif; other site
761193002935	TPR repeat; Region: TPR_11; pfam13414
761193002936	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193002937	binding surface
761193002938	TPR motif; other site
761193002939	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
761193002940	UbiA prenyltransferase family; Region: UbiA; pfam01040
761193002941	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
761193002942	FAD binding domain; Region: FAD_binding_4; pfam01565
761193002943	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
761193002944	Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; cl17818
761193002945	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
761193002946	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
761193002947	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
761193002948	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
761193002949	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
761193002950	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
761193002951	xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964
761193002952	XdhC Rossmann domain; Region: XdhC_C; pfam13478
761193002953	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
761193002954	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
761193002955	dimer interface [polypeptide binding]; other site
761193002956	putative functional site; other site
761193002957	putative MPT binding site; other site
761193002958	ribonucleoside--diphosphate reductase large subunit; Region: PLN02437
761193002959	ATP cone domain; Region: ATP-cone; pfam03477
761193002960	Class I ribonucleotide reductase; Region: RNR_I; cd01679
761193002961	active site
761193002962	dimer interface [polypeptide binding]; other site
761193002963	catalytic residues [active]
761193002964	effector binding site; other site
761193002965	R2 peptide binding site; other site
761193002966	hypothetical protein; Validated; Region: PRK00153
761193002967	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
761193002968	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
761193002969	Probable Catalytic site; other site
761193002970	metal-binding site
761193002971	rod shape-determining protein MreB; Provisional; Region: PRK13927
761193002972	MreB and similar proteins; Region: MreB_like; cd10225
761193002973	nucleotide binding site [chemical binding]; other site
761193002974	Mg binding site [ion binding]; other site
761193002975	putative protofilament interaction site [polypeptide binding]; other site
761193002976	RodZ interaction site [polypeptide binding]; other site
761193002977	rod shape-determining protein MreC; Provisional; Region: PRK13922
761193002978	rod shape-determining protein MreC; Region: MreC; pfam04085
761193002979	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
761193002980	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193002981	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193002982	DNA binding residues [nucleotide binding]
761193002983	mycothiol system anti-sigma-R factor; Region: antisig_RsrA; cl15806
761193002984	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
761193002985	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
761193002986	catalytic site [active]
761193002987	G-X2-G-X-G-K; other site
761193002988	putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018
761193002989	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
761193002990	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193002991	Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939
761193002992	Serine carboxypeptidase; Region: Peptidase_S10; cl08270
761193002993	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193002994	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193002995	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
761193002996	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193002997	putative catalytic residue [active]
761193002998	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193002999	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193003000	catalytic residues [active]
761193003001	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
761193003002	Active_site [active]
761193003003	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003004	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193003005	active site
761193003006	phosphorylation site [posttranslational modification]
761193003007	intermolecular recognition site; other site
761193003008	dimerization interface [polypeptide binding]; other site
761193003009	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
761193003010	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
761193003011	HflX GTPase family; Region: HflX; cd01878
761193003012	G1 box; other site
761193003013	GTP/Mg2+ binding site [chemical binding]; other site
761193003014	Switch I region; other site
761193003015	G2 box; other site
761193003016	G3 box; other site
761193003017	Switch II region; other site
761193003018	G4 box; other site
761193003019	G5 box; other site
761193003020	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
761193003021	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
761193003022	Serine hydrolase (FSH1); Region: FSH1; pfam03959
761193003023	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like5; cd05651
761193003024	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
761193003025	metal binding site [ion binding]; metal-binding site
761193003026	dimer interface [polypeptide binding]; other site
761193003027	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
761193003028	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
761193003029	homodimer interface [polypeptide binding]; other site
761193003030	metal binding site [ion binding]; metal-binding site
761193003031	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
761193003032	homodimer interface [polypeptide binding]; other site
761193003033	active site
761193003034	putative chemical substrate binding site [chemical binding]; other site
761193003035	metal binding site [ion binding]; metal-binding site
761193003036	Protein of unknown function, DUF481; Region: DUF481; cl01213
761193003037	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
761193003038	putative active site pocket [active]
761193003039	dimerization interface [polypeptide binding]; other site
761193003040	putative catalytic residue [active]
761193003041	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003042	Protein of unknown function (DUF2853); Region: DUF2853; pfam11015
761193003043	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; pfam10079
761193003044	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365
761193003045	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
761193003046	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
761193003047	Ligand binding site; other site
761193003048	Putative Catalytic site; other site
761193003049	DXD motif; other site
761193003050	aspartate kinase III; Validated; Region: PRK09084
761193003051	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
761193003052	nucleotide binding site [chemical binding]; other site
761193003053	substrate binding site [chemical binding]; other site
761193003054	ACT domains located C-terminal to the catalytic domain of  the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC-like_1; cd04912
761193003055	dimer interface [polypeptide binding]; other site
761193003056	allosteric regulatory binding pocket; other site
761193003057	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
761193003058	Transposase IS200 like; Region: Y1_Tnp; pfam01797
761193003059	seryl-tRNA synthetase; Provisional; Region: PRK05431
761193003060	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
761193003061	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
761193003062	motif 1; other site
761193003063	dimer interface [polypeptide binding]; other site
761193003064	active site
761193003065	motif 2; other site
761193003066	motif 3; other site
761193003067	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
761193003068	active site
761193003069	Protein of unknown function, DUF606; Region: DUF606; pfam04657
761193003070	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193003071	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193003072	FtsX-like permease family; Region: FtsX; pfam02687
761193003073	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
761193003074	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
761193003075	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
761193003076	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193003077	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193003078	active site residue [active]
761193003079	ribosome recycling factor; Reviewed; Region: frr; PRK00083
761193003080	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
761193003081	hinge region; other site
761193003082	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193003083	Walker A/P-loop; other site
761193003084	ATP binding site [chemical binding]; other site
761193003085	AAA domain; Region: AAA_21; pfam13304
761193003086	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
761193003087	putative nucleotide binding site [chemical binding]; other site
761193003088	uridine monophosphate binding site [chemical binding]; other site
761193003089	homohexameric interface [polypeptide binding]; other site
761193003090	putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK05641
761193003091	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
761193003092	carboxyltransferase (CT) interaction site; other site
761193003093	biotinylation site [posttranslational modification]; other site
761193003094	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
761193003095	EamA-like transporter family; Region: EamA; pfam00892
761193003096	EamA-like transporter family; Region: EamA; pfam00892
761193003097	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
761193003098	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system [Function unknown]; Region: COG4946
761193003099	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193003100	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193003101	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
761193003102	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
761193003103	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
761193003104	protein binding site [polypeptide binding]; other site
761193003105	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
761193003106	Domain interface; other site
761193003107	Peptide binding site; other site
761193003108	Active site tetrad [active]
761193003109	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
761193003110	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
761193003111	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
761193003112	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
761193003113	Transposase IS200 like; Region: Y1_Tnp; cl00848
761193003114	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193003115	PA_GCPII_like: Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to...; Region: PA_GCPII_like; cd02121
761193003116	apical/protease domain interface [polypeptide binding]; other site
761193003117	substrate binding [chemical binding]; other site
761193003118	dimer interface [polypeptide binding]; other site
761193003119	M28 Zn-peptidase prostate-specific membrane antigen; Region: M28_PSMA_like; cd08022
761193003120	dimer interface [polypeptide binding]; other site
761193003121	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193003122	active site
761193003123	metal binding site [ion binding]; metal-binding site
761193003124	Transferrin receptor-like dimerisation domain; Region: TFR_dimer; pfam04253
761193003125	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193003126	Protein of unknown function (DUF1549); Region: PSCyt2; pfam07583
761193003127	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
761193003128	Protein of unknown function (DUF1553); Region: PSD1; pfam07587
761193003129	Protein of unknown function (DUF1501); Region: DUF1501; pfam07394
761193003130	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
761193003131	isocitrate dehydrogenase; Validated; Region: PRK08299
761193003132	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
761193003133	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
761193003134	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
761193003135	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
761193003136	nucleotide binding site [chemical binding]; other site
761193003137	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
761193003138	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
761193003139	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
761193003140	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
761193003141	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
761193003142	putative active site [active]
761193003143	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
761193003144	KEGG: dfe:Dfer_2478 hypothetical protein; SPTR:  uncharacterized protein
761193003145	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
761193003146	metal ion-dependent adhesion site (MIDAS); other site
761193003147	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
761193003148	Peptidase S8 family domain in Subtilisin proteins; Region: Peptidases_S8_Subtilisin_subset; cd07477
761193003149	active site
761193003150	catalytic residues [active]
761193003151	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
761193003152	PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398
761193003153	active site
761193003154	COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845:IPR005843; KEGG: sli:Slin_2856 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, C-terminal; PRIAM: Phosphoglucosamine mutase; SPTR: Phosphomannomutase
761193003155	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
761193003156	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
761193003157	active site
761193003158	substrate binding site [chemical binding]; other site
761193003159	metal binding site [ion binding]; metal-binding site
761193003160	Predicted acyl esterases [General function prediction only]; Region: COG2936
761193003161	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
761193003162	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
761193003163	Quinone oxidoreductase (QOR); Region: QOR1; cd08241
761193003164	NAD(P) binding site [chemical binding]; other site
761193003165	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
761193003166	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193003167	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193003168	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003169	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193003170	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193003171	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
761193003172	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193003173	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193003174	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003175	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193003176	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193003177	Protein of unknown function (DUF1361); Region: DUF1361; pfam07099
761193003178	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
761193003179	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193003180	putative DNA binding site [nucleotide binding]; other site
761193003181	dimerization interface [polypeptide binding]; other site
761193003182	Transcriptional regulators [Transcription]; Region: MarR; COG1846
761193003183	putative Zn2+ binding site [ion binding]; other site
761193003184	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193003185	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003186	Gram-negative bacterial tonB protein; Region: TonB; cl10048
761193003187	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193003188	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193003189	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193003190	DNA binding residues [nucleotide binding]
761193003191	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003192	von Willebrand factor; Region: vWF_A; pfam12450
761193003193	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
761193003194	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
761193003195	metal ion-dependent adhesion site (MIDAS); other site
761193003196	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
761193003197	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193003198	short chain dehydrogenase; Provisional; Region: PRK07326
761193003199	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193003200	NAD(P) binding site [chemical binding]; other site
761193003201	active site
761193003202	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
761193003203	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193003204	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193003205	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193003206	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193003207	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
761193003208	dimerization interface [polypeptide binding]; other site
761193003209	ATP binding site [chemical binding]; other site
761193003210	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
761193003211	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
761193003212	motif 1; other site
761193003213	active site
761193003214	motif 2; other site
761193003215	motif 3; other site
761193003216	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
761193003217	DHHA1 domain; Region: DHHA1; pfam02272
761193003218	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193003219	SdiA-regulated; Region: SdiA-regulated; cd09971
761193003220	putative active site [active]
761193003221	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
761193003222	Domain of unknown function DUF20; Region: UPF0118; pfam01594
761193003223	conserved hypothetical protein, HNE_0200 family; Region: chp_HNE_0200; TIGR03806
761193003224	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193003225	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
761193003226	dimerization interface [polypeptide binding]; other site
761193003227	PAS domain; Region: PAS; smart00091
761193003228	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
761193003229	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193003230	ATP binding site [chemical binding]; other site
761193003231	Mg2+ binding site [ion binding]; other site
761193003232	G-X-G motif; other site
761193003233	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
761193003234	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
761193003235	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003236	active site
761193003237	phosphorylation site [posttranslational modification]
761193003238	intermolecular recognition site; other site
761193003239	dimerization interface [polypeptide binding]; other site
761193003240	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193003241	Walker A motif; other site
761193003242	ATP binding site [chemical binding]; other site
761193003243	Walker B motif; other site
761193003244	arginine finger; other site
761193003245	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
761193003246	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193003247	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193003248	FtsX-like permease family; Region: FtsX; pfam02687
761193003249	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193003250	FtsX-like permease family; Region: FtsX; pfam02687
761193003251	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
761193003252	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
761193003253	Walker A/P-loop; other site
761193003254	ATP binding site [chemical binding]; other site
761193003255	Q-loop/lid; other site
761193003256	ABC transporter signature motif; other site
761193003257	Walker B; other site
761193003258	D-loop; other site
761193003259	H-loop/switch region; other site
761193003260	Outer membrane efflux protein; Region: OEP; pfam02321
761193003261	Outer membrane efflux protein; Region: OEP; pfam02321
761193003262	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193003263	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193003264	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
761193003265	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
761193003266	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
761193003267	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193003268	catalytic loop [active]
761193003269	iron binding site [ion binding]; other site
761193003270	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
761193003271	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
761193003272	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
761193003273	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193003274	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193003275	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
761193003276	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
761193003277	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
761193003278	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193003279	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
761193003280	exopolyphosphatase; Region: exo_poly_only; TIGR03706
761193003281	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193003282	LytTr DNA-binding domain; Region: LytTR; smart00850
761193003283	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
761193003284	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
761193003285	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
761193003286	Conserved TM helix; Region: TM_helix; pfam05552
761193003287	Mechanosensitive ion channel; Region: MS_channel; pfam00924
761193003288	RNA polymerase sigma factor; Provisional; Region: PRK12541
761193003289	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193003290	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193003291	DNA binding residues [nucleotide binding]
761193003292	elongation factor Ts; Provisional; Region: tsf; PRK09377
761193003293	UBA/TS-N domain; Region: UBA; pfam00627
761193003294	Elongation factor TS; Region: EF_TS; pfam00889
761193003295	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
761193003296	rRNA interaction site [nucleotide binding]; other site
761193003297	S8 interaction site; other site
761193003298	putative laminin-1 binding site; other site
761193003299	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
761193003300	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
761193003301	23S rRNA interface [nucleotide binding]; other site
761193003302	L3 interface [polypeptide binding]; other site
761193003303	L-aspartate oxidase; Provisional; Region: PRK09077
761193003304	L-aspartate oxidase; Provisional; Region: PRK06175
761193003305	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
761193003306	Demethylmenaquinone methyltransferase; Region: Methyltransf_6; cl00480
761193003307	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
761193003308	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193003309	active site pocket [active]
761193003310	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
761193003311	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
761193003312	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
761193003313	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193003314	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193003315	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
761193003316	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
761193003317	NAD(P) binding site [chemical binding]; other site
761193003318	short chain dehydrogenase; Validated; Region: PRK08324
761193003319	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; smart01007
761193003320	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193003321	NAD(P) binding site [chemical binding]; other site
761193003322	active site
761193003323	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
761193003324	L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype; Region: L_rham_iso_rhiz; TIGR02629
761193003325	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
761193003326	nucleotide binding site [chemical binding]; other site
761193003327	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
761193003328	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
761193003329	Beta-Casp domain; Region: Beta-Casp; smart01027
761193003330	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
761193003331	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193003332	Protein of unknown function (DUF1549); Region: PSCyt2; pfam07583
761193003333	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
761193003334	metal binding site [ion binding]; metal-binding site
761193003335	ligand binding site [chemical binding]; other site
761193003336	Protein of unknown function (DUF1553); Region: PSD1; pfam07587
761193003337	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
761193003338	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
761193003339	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193003340	Protein of unknown function (DUF3530); Region: DUF3530; pfam12048
761193003341	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
761193003342	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193003343	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
761193003344	active site
761193003345	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193003346	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
761193003347	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
761193003348	ATP binding site [chemical binding]; other site
761193003349	Mg++ binding site [ion binding]; other site
761193003350	motif III; other site
761193003351	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193003352	nucleotide binding region [chemical binding]; other site
761193003353	ATP-binding site [chemical binding]; other site
761193003354	Transposase IS200 like; Region: Y1_Tnp; pfam01797
761193003355	Methane oxygenase PmoA; Region: PmoA; pfam14100
761193003356	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193003357	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
761193003358	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
761193003359	Periplasmic binding domain of two-component sensor kinase signaling systems; Region: PBP1_sensor_kinase_like; cd06308
761193003360	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
761193003361	putative ligand binding site [chemical binding]; other site
761193003362	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193003363	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193003364	dimer interface [polypeptide binding]; other site
761193003365	phosphorylation site [posttranslational modification]
761193003366	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193003367	ATP binding site [chemical binding]; other site
761193003368	Mg2+ binding site [ion binding]; other site
761193003369	G-X-G motif; other site
761193003370	Response regulator receiver domain; Region: Response_reg; pfam00072
761193003371	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003372	active site
761193003373	phosphorylation site [posttranslational modification]
761193003374	intermolecular recognition site; other site
761193003375	dimerization interface [polypeptide binding]; other site
761193003376	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193003377	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193003378	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
761193003379	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193003380	putative substrate translocation pore; other site
761193003381	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193003382	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
761193003383	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
761193003384	putative substrate binding site [chemical binding]; other site
761193003385	putative ATP binding site [chemical binding]; other site
761193003386	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193003387	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003388	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193003389	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193003390	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193003391	SusD family; Region: SusD; pfam07980
761193003392	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
761193003393	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
761193003394	substrate binding [chemical binding]; other site
761193003395	active site
761193003396	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
761193003397	2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism]; Region: HpcH; COG3836
761193003398	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
761193003399	fructuronate transporter; Provisional; Region: PRK10034; cl15264
761193003400	fructuronate transporter; Provisional; Region: PRK10034; cl15264
761193003401	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
761193003402	galactarate dehydratase; Region: galactar-dH20; TIGR03248
761193003403	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
761193003404	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
761193003405	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
761193003406	D-mannonate dehydratase [Carbohydrate transport and metabolism]; Region: UxuA; COG1312
761193003407	mannonate dehydratase; Region: uxuA; TIGR00695
761193003408	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
761193003409	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
761193003410	metal binding site [ion binding]; metal-binding site
761193003411	substrate binding pocket [chemical binding]; other site
761193003412	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193003413	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193003414	sequence-specific DNA binding site [nucleotide binding]; other site
761193003415	salt bridge; other site
761193003416	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
761193003417	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
761193003418	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
761193003419	cofactor binding site; other site
761193003420	DNA binding site [nucleotide binding]
761193003421	substrate interaction site [chemical binding]; other site
761193003422	Protein of unknown function (DUF3380); Region: DUF3380; pfam11860
761193003423	NVEALA protein; Region: NVEALA; pfam14055
761193003424	Uncharacterized protein conserved in bacteria (DUF2188); Region: DUF2188; pfam09954
761193003425	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193003426	active site
761193003427	DNA binding site [nucleotide binding]
761193003428	Int/Topo IB signature motif; other site
761193003429	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
761193003430	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
761193003431	substrate binding site [chemical binding]; other site
761193003432	ATP binding site [chemical binding]; other site
761193003433	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
761193003434	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193003435	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193003436	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003437	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193003438	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193003439	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
761193003440	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
761193003441	active site
761193003442	nucleophile elbow; other site
761193003443	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
761193003444	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
761193003445	dimer interface [polypeptide binding]; other site
761193003446	active site
761193003447	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
761193003448	catalytic residues [active]
761193003449	substrate binding site [chemical binding]; other site
761193003450	Predicted transcriptional regulator [Transcription]; Region: COG1959
761193003451	Transcriptional regulator; Region: Rrf2; pfam02082
761193003452	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
761193003453	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
761193003454	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
761193003455	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
761193003456	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193003457	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193003458	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK07204
761193003459	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
761193003460	active site
761193003461	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
761193003462	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
761193003463	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
761193003464	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193003465	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193003466	NAD(P) binding site [chemical binding]; other site
761193003467	active site
761193003468	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
761193003469	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193003470	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
761193003471	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
761193003472	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
761193003473	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
761193003474	hypothetical protein; Provisional; Region: PRK00955
761193003475	helicase 45; Provisional; Region: PTZ00424
761193003476	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
761193003477	ATP binding site [chemical binding]; other site
761193003478	Mg++ binding site [ion binding]; other site
761193003479	motif III; other site
761193003480	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193003481	nucleotide binding region [chemical binding]; other site
761193003482	ATP-binding site [chemical binding]; other site
761193003483	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
761193003484	RNA binding site [nucleotide binding]; other site
761193003485	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
761193003486	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193003487	Walker A/P-loop; other site
761193003488	ATP binding site [chemical binding]; other site
761193003489	Q-loop/lid; other site
761193003490	ABC transporter signature motif; other site
761193003491	Walker B; other site
761193003492	D-loop; other site
761193003493	H-loop/switch region; other site
761193003494	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
761193003495	active site
761193003496	intersubunit interactions; other site
761193003497	catalytic residue [active]
761193003498	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193003499	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003500	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193003501	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193003502	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193003503	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193003504	SusD family; Region: SusD; pfam07980
761193003505	Family description; Region: VCBS; pfam13517
761193003506	Family description; Region: VCBS; pfam13517
761193003507	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
761193003508	FG-GAP repeat; Region: FG-GAP; pfam01839
761193003509	Family description; Region: VCBS; pfam13517
761193003510	Family description; Region: VCBS; pfam13517
761193003511	Family description; Region: VCBS; pfam13517
761193003512	Family description; Region: VCBS; pfam13517
761193003513	Family description; Region: VCBS; pfam13517
761193003514	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
761193003515	FG-GAP repeat; Region: FG-GAP; pfam01839
761193003516	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193003517	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003518	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193003519	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193003520	hypothetical protein; Provisional; Region: PRK06849
761193003521	ATP-grasp domain; Region: ATP-grasp_4; cl17255
761193003522	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
761193003523	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
761193003524	iron-sulfur cluster [ion binding]; other site
761193003525	[2Fe-2S] cluster binding site [ion binding]; other site
761193003526	ribonuclease R; Region: RNase_R; TIGR02063
761193003527	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
761193003528	RNB domain; Region: RNB; pfam00773
761193003529	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
761193003530	RNA binding site [nucleotide binding]; other site
761193003531	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
761193003532	radical SAM/Cys-rich domain protein; Region: rSAM_SeCys; TIGR04167
761193003533	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193003534	FeS/SAM binding site; other site
761193003535	Protein of unknown function (DUF3641); Region: DUF3641; pfam12345
761193003536	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193003537	non-specific DNA binding site [nucleotide binding]; other site
761193003538	salt bridge; other site
761193003539	sequence-specific DNA binding site [nucleotide binding]; other site
761193003540	HipA N-terminal domain; Region: Couple_hipA; pfam13657
761193003541	HipA-like N-terminal domain; Region: HipA_N; pfam07805
761193003542	HipA-like C-terminal domain; Region: HipA_C; pfam07804
761193003543	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
761193003544	active site
761193003545	metal binding site [ion binding]; metal-binding site
761193003546	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193003547	active site
761193003548	metal binding site [ion binding]; metal-binding site
761193003549	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
761193003550	Na binding site [ion binding]; other site
761193003551	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
761193003552	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193003553	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193003554	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003555	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193003556	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193003557	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
761193003558	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
761193003559	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
761193003560	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
761193003561	classical (c) SDRs; Region: SDR_c; cd05233
761193003562	NAD(P) binding site [chemical binding]; other site
761193003563	active site
761193003564	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
761193003565	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
761193003566	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
761193003567	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
761193003568	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
761193003569	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
761193003570	quinone interaction residues [chemical binding]; other site
761193003571	active site
761193003572	catalytic residues [active]
761193003573	FMN binding site [chemical binding]; other site
761193003574	substrate binding site [chemical binding]; other site
761193003575	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
761193003576	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
761193003577	Putative catalytic NodB homology domain of gellan lyase and similar proteins; Region: CE4_GLA_like_6s; cd10967
761193003578	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
761193003579	putative active site [active]
761193003580	putative metal binding site [ion binding]; other site
761193003581	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
761193003582	active site
761193003583	hypothetical protein; Reviewed; Region: PRK12497
761193003584	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
761193003585	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193003586	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193003587	DNA helicase, putative; Region: TIGR00376
761193003588	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193003589	ATP binding site [chemical binding]; other site
761193003590	AAA domain; Region: AAA_12; pfam13087
761193003591	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193003592	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
761193003593	DNA interaction; other site
761193003594	Metal-binding active site; metal-binding site
761193003595	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
761193003596	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193003597	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193003598	Immediate early response protein (IER); Region: IER; pfam05760
761193003599	Trehalose utilisation; Region: ThuA; pfam06283
761193003600	conserved cys residue [active]
761193003601	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193003602	HEAT repeats; Region: HEAT_2; pfam13646
761193003603	CARDB; Region: CARDB; pfam07705
761193003604	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
761193003605	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
761193003606	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
761193003607	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
761193003608	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
761193003609	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193003610	RibD C-terminal domain; Region: RibD_C; cl17279
761193003611	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
761193003612	Protein of unknown function (DUF419); Region: DUF419; pfam04237
761193003613	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
761193003614	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
761193003615	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
761193003616	hydrophobic ligand binding site; other site
761193003617	YCII-related domain; Region: YCII; cl00999
761193003618	Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription]; Region: COG4941
761193003619	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193003620	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193003621	DNA binding residues [nucleotide binding]
761193003622	Pirin; Region: Pirin; pfam02678
761193003623	Pirin-related protein [General function prediction only]; Region: COG1741
761193003624	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
761193003625	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
761193003626	putative hydrolase; Provisional; Region: PRK11460
761193003627	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
761193003628	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193003629	Zn binding site [ion binding]; other site
761193003630	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
761193003631	Zn binding site [ion binding]; other site
761193003632	MarR family; Region: MarR_2; pfam12802
761193003633	Transcriptional regulators [Transcription]; Region: MarR; COG1846
761193003634	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193003635	Coenzyme A binding pocket [chemical binding]; other site
761193003636	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
761193003637	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193003638	Zn binding site [ion binding]; other site
761193003639	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
761193003640	Zn binding site [ion binding]; other site
761193003641	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193003642	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193003643	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
761193003644	putative active site [active]
761193003645	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
761193003646	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193003647	Walker A motif; other site
761193003648	ATP binding site [chemical binding]; other site
761193003649	Walker B motif; other site
761193003650	arginine finger; other site
761193003651	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
761193003652	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
761193003653	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
761193003654	non-specific DNA binding site [nucleotide binding]; other site
761193003655	salt bridge; other site
761193003656	sequence-specific DNA binding site [nucleotide binding]; other site
761193003657	Ndr family; Region: Ndr; pfam03096
761193003658	putative outer membrane lipoprotein; Provisional; Region: PRK10510
761193003659	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193003660	ligand binding site [chemical binding]; other site
761193003661	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
761193003662	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
761193003663	dimerization interface [polypeptide binding]; other site
761193003664	DPS ferroxidase diiron center [ion binding]; other site
761193003665	ion pore; other site
761193003666	KEGG: mev:Metev_0960 hypothetical protein; SPTR:  uncharacterized protein
761193003667	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193003668	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003669	active site
761193003670	phosphorylation site [posttranslational modification]
761193003671	intermolecular recognition site; other site
761193003672	dimerization interface [polypeptide binding]; other site
761193003673	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
761193003674	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193003675	putative active site [active]
761193003676	heme pocket [chemical binding]; other site
761193003677	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193003678	dimer interface [polypeptide binding]; other site
761193003679	phosphorylation site [posttranslational modification]
761193003680	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193003681	ATP binding site [chemical binding]; other site
761193003682	G-X-G motif; other site
761193003683	Response regulator receiver domain; Region: Response_reg; pfam00072
761193003684	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003685	active site
761193003686	phosphorylation site [posttranslational modification]
761193003687	intermolecular recognition site; other site
761193003688	dimerization interface [polypeptide binding]; other site
761193003689	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193003690	PAS fold; Region: PAS_3; pfam08447
761193003691	putative active site [active]
761193003692	heme pocket [chemical binding]; other site
761193003693	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193003694	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193003695	dimer interface [polypeptide binding]; other site
761193003696	phosphorylation site [posttranslational modification]
761193003697	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193003698	ATP binding site [chemical binding]; other site
761193003699	Mg2+ binding site [ion binding]; other site
761193003700	G-X-G motif; other site
761193003701	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
761193003702	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003703	active site
761193003704	phosphorylation site [posttranslational modification]
761193003705	intermolecular recognition site; other site
761193003706	dimerization interface [polypeptide binding]; other site
761193003707	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193003708	Walker A motif; other site
761193003709	ATP binding site [chemical binding]; other site
761193003710	Walker B motif; other site
761193003711	arginine finger; other site
761193003712	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
761193003713	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
761193003714	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
761193003715	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
761193003716	CHASE3 domain; Region: CHASE3; pfam05227
761193003717	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193003718	dimer interface [polypeptide binding]; other site
761193003719	phosphorylation site [posttranslational modification]
761193003720	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193003721	ATP binding site [chemical binding]; other site
761193003722	Mg2+ binding site [ion binding]; other site
761193003723	G-X-G motif; other site
761193003724	Response regulator receiver domain; Region: Response_reg; pfam00072
761193003725	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003726	active site
761193003727	phosphorylation site [posttranslational modification]
761193003728	intermolecular recognition site; other site
761193003729	dimerization interface [polypeptide binding]; other site
761193003730	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003731	Response regulator receiver domain; Region: Response_reg; pfam00072
761193003732	active site
761193003733	phosphorylation site [posttranslational modification]
761193003734	intermolecular recognition site; other site
761193003735	dimerization interface [polypeptide binding]; other site
761193003736	Domain of unknown function (DUF2383); Region: DUF2383; cl17556
761193003737	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193003738	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193003739	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193003740	DNA binding residues [nucleotide binding]
761193003741	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
761193003742	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
761193003743	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
761193003744	1,4-alpha-glucan branching enzyme [Carbohydrate transport and metabolism]; Region: GlgB; COG0296
761193003745	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
761193003746	catalytic site [active]
761193003747	active site
761193003748	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
761193003749	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
761193003750	Domain of unknown function DUF20; Region: UPF0118; pfam01594
761193003751	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193003752	Trehalose utilisation; Region: ThuA; pfam06283
761193003753	beta-carotene hydroxylase; Region: PLN02601
761193003754	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
761193003755	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
761193003756	active site
761193003757	Zn binding site [ion binding]; other site
761193003758	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
761193003759	putative active site [active]
761193003760	homotetrameric interface [polypeptide binding]; other site
761193003761	metal binding site [ion binding]; metal-binding site
761193003762	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193003763	PA_M28_2: Protease-associated (PA) domain, peptidase family M28, subfamily-2. A subfamily of PA-domain containing proteins belonging to the peptidase family M28. Family M28 contains aminopeptidases and carboxypeptidases, and has co-catalytic zinc ions; Region: PA_M28_2; cd04815
761193003764	PA/protease or protease-like domain interface [polypeptide binding]; other site
761193003765	M28 Zn-Peptidase Plasma glutamate carboxypeptidase; Region: M28_Pgcp_like; cd03883
761193003766	metal binding site [ion binding]; metal-binding site
761193003767	Protein of unknown function (DUF1501); Region: DUF1501; pfam07394
761193003768	Alkane hydroxylase is a bacterial, integral-membrane di-iron enzyme that shares a requirement for iron and oxygen for activity similar to that of the non-heme integral-membrane acyl coenzyme A (CoA) desaturases and acyl lipid desaturases. The alk genes...; Region: Alkane-hydroxylase; cd03512
761193003769	Fatty acid desaturase; Region: FA_desaturase; pfam00487
761193003770	Di-iron ligands [ion binding]; other site
761193003771	Protein of unknown function (DUF2846); Region: DUF2846; pfam11008
761193003772	Histidine kinase; Region: His_kinase; pfam06580
761193003773	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
761193003774	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003775	active site
761193003776	phosphorylation site [posttranslational modification]
761193003777	intermolecular recognition site; other site
761193003778	dimerization interface [polypeptide binding]; other site
761193003779	LytTr DNA-binding domain; Region: LytTR; smart00850
761193003780	Protein of unknown function (DUF433); Region: DUF433; pfam04255
761193003781	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
761193003782	DNA photolyase; Region: DNA_photolyase; pfam00875
761193003783	FOG: CBS domain [General function prediction only]; Region: COG0517
761193003784	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
761193003785	glycine dehydrogenase; Provisional; Region: PRK05367
761193003786	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
761193003787	tetramer interface [polypeptide binding]; other site
761193003788	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193003789	catalytic residue [active]
761193003790	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
761193003791	tetramer interface [polypeptide binding]; other site
761193003792	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193003793	catalytic residue [active]
761193003794	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
761193003795	Aromatic ring hydroxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2368
761193003796	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
761193003797	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
761193003798	enoyl-CoA hydratase; Provisional; Region: PRK07657
761193003799	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
761193003800	substrate binding site [chemical binding]; other site
761193003801	oxyanion hole (OAH) forming residues; other site
761193003802	trimer interface [polypeptide binding]; other site
761193003803	Class I hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classI; cd00643
761193003804	tetramerization interface [polypeptide binding]; other site
761193003805	substrate binding pocket [chemical binding]; other site
761193003806	catalytic residues [active]
761193003807	inhibitor binding sites; inhibition site
761193003808	NADP(H) binding site [chemical binding]; other site
761193003809	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
761193003810	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
761193003811	putative active site [active]
761193003812	metal binding site [ion binding]; metal-binding site
761193003813	Glycoside hydrolase family 44; Region: Glyco_hydro_44; pfam12891
761193003814	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; cl01412
761193003815	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193003816	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
761193003817	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
761193003818	active site
761193003819	catalytic tetrad [active]
761193003820	Domain of unknown function (DUF718); Region: DUF718; pfam05336
761193003821	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193003822	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193003823	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193003824	Protein of unknown function, DUF547; Region: DUF547; pfam04784
761193003825	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
761193003826	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193003827	NAD(P) binding site [chemical binding]; other site
761193003828	active site
761193003829	(R)-hydratase [(R)-specific enoyl-CoA hydratase] catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. (R)-hydratase contains a hot-dog fold similar to those of thioesterase...; Region: R_hydratase; cd03449
761193003830	dimer interaction site [polypeptide binding]; other site
761193003831	substrate-binding tunnel; other site
761193003832	active site
761193003833	catalytic site [active]
761193003834	substrate binding site [chemical binding]; other site
761193003835	Maf-like protein; Region: Maf; pfam02545
761193003836	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
761193003837	active site
761193003838	dimer interface [polypeptide binding]; other site
761193003839	carotene biosynthesis associated membrane protein; Region: crt_membr; TIGR03459
761193003840	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
761193003841	ribonuclease P; Reviewed; Region: rnpA; PRK01903
761193003842	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193003843	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193003844	active site
761193003845	phosphorylation site [posttranslational modification]
761193003846	intermolecular recognition site; other site
761193003847	dimerization interface [polypeptide binding]; other site
761193003848	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193003849	DNA binding site [nucleotide binding]
761193003850	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
761193003851	NADH dehydrogenase subunit D; Validated; Region: PRK06075
761193003852	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
761193003853	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193003854	Bacterial SH3 domain; Region: SH3_3; cl17532
761193003855	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193003856	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193003857	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193003858	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
761193003859	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
761193003860	active site
761193003861	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
761193003862	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
761193003863	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
761193003864	metal ion-dependent adhesion site (MIDAS); other site
761193003865	Domain of unknown function (DUF4296); Region: DUF4296; pfam14129
761193003866	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
761193003867	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
761193003868	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
761193003869	nudix motif; other site
761193003870	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
761193003871	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
761193003872	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
761193003873	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193003874	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
761193003875	DNA polymerase III subunit beta; Validated; Region: PRK05643
761193003876	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
761193003877	putative DNA binding surface [nucleotide binding]; other site
761193003878	dimer interface [polypeptide binding]; other site
761193003879	beta-clamp/clamp loader binding surface; other site
761193003880	beta-clamp/translesion DNA polymerase binding surface; other site
761193003881	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
761193003882	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
761193003883	Tetramer interface [polypeptide binding]; other site
761193003884	active site
761193003885	FMN-binding site [chemical binding]; other site
761193003886	Oxygen tolerance; Region: BatD; pfam13584
761193003887	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193003888	binding surface
761193003889	TPR repeat; Region: TPR_11; pfam13414
761193003890	TPR motif; other site
761193003891	PBP superfamily domain; Region: PBP_like_2; pfam12849
761193003892	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
761193003893	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
761193003894	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
761193003895	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
761193003896	short chain dehydrogenase; Provisional; Region: PRK08278
761193003897	human hydroxysteroid dehydrogenase-like protein 2 (HSDL2), classical (c) SDRs; Region: HSDL2_SDR_c; cd09762
761193003898	NAD(P) binding site [chemical binding]; other site
761193003899	homodimer interface [polypeptide binding]; other site
761193003900	active site
761193003901	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193003902	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
761193003903	binding surface
761193003904	TPR motif; other site
761193003905	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193003906	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193003907	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193003908	ligand binding site [chemical binding]; other site
761193003909	GH3 auxin-responsive promoter; Region: GH3; pfam03321
761193003910	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
761193003911	N-acetyl-D-glucosamine binding site [chemical binding]; other site
761193003912	catalytic residue [active]
761193003913	Uncharacterized conserved protein [Function unknown]; Region: COG2353
761193003914	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
761193003915	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
761193003916	Ligand binding site; other site
761193003917	Putative Catalytic site; other site
761193003918	DXD motif; other site
761193003919	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
761193003920	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
761193003921	substrate binding site [chemical binding]; other site
761193003922	active site
761193003923	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
761193003924	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
761193003925	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
761193003926	FeoA domain; Region: FeoA; pfam04023
761193003927	Heavy-metal resistance; Region: Metal_resist; pfam13801
761193003928	dimer interface [polypeptide binding]; other site
761193003929	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193003930	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193003931	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193003932	DNA binding residues [nucleotide binding]
761193003933	manganese transport protein MntH; Reviewed; Region: PRK00701
761193003934	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
761193003935	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
761193003936	Protein of unknown function (DUF2851); Region: DUF2851; pfam11013
761193003937	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193003938	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
761193003939	PA/protease or protease-like domain interface [polypeptide binding]; other site
761193003940	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
761193003941	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193003942	metal binding site [ion binding]; metal-binding site
761193003943	AAA domain; Region: AAA_21; pfam13304
761193003944	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
761193003945	Q-loop/lid; other site
761193003946	Walker B; other site
761193003947	D-loop; other site
761193003948	H-loop/switch region; other site
761193003949	Homeodomain-like domain; Region: HTH_23; pfam13384
761193003950	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193003951	Homeodomain-like domain; Region: HTH_32; pfam13565
761193003952	Winged helix-turn helix; Region: HTH_33; pfam13592
761193003953	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193003954	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193003955	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
761193003956	MG2 domain; Region: A2M_N; pfam01835
761193003957	Alpha-2-macroglobulin family; Region: A2M; pfam00207
761193003958	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
761193003959	surface patch; other site
761193003960	thioester region; other site
761193003961	specificity defining residues; other site
761193003962	COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: dfe:Dfer_0227 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related
761193003963	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
761193003964	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193003965	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193003966	ABC transporter; Region: ABC_tran_2; pfam12848
761193003967	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193003968	2TM domain; Region: 2TM; pfam13239
761193003969	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
761193003970	active site
761193003971	metal binding site [ion binding]; metal-binding site
761193003972	Recombination protein O N terminal; Region: RecO_N; pfam11967
761193003973	Recombination protein O C terminal; Region: RecO_C; pfam02565
761193003974	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
761193003975	nucleotide binding site [chemical binding]; other site
761193003976	N-acetyl-L-glutamate binding site [chemical binding]; other site
761193003977	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199
761193003978	homotrimer interaction site [polypeptide binding]; other site
761193003979	putative active site [active]
761193003980	Motility related/secretion protein; Region: SprA_N; pfam14349
761193003981	cell surface protein SprA; Region: surface_SprA; TIGR04189
761193003982	Motility related/secretion protein; Region: SprA_N; pfam14349
761193003983	Motility related/secretion protein; Region: SprA_N; pfam14349
761193003984	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
761193003985	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
761193003986	purine monophosphate binding site [chemical binding]; other site
761193003987	dimer interface [polypeptide binding]; other site
761193003988	putative catalytic residues [active]
761193003989	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
761193003990	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
761193003991	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193003992	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193003993	putative substrate translocation pore; other site
761193003994	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193003995	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
761193003996	Transposase IS200 like; Region: Y1_Tnp; cl00848
761193003997	Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; Region: ALDH_F4-17_P5CDH; cd07123
761193003998	delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; Region: D1pyr5carbox1; TIGR01236
761193003999	Glutamate binding site [chemical binding]; other site
761193004000	NAD binding site [chemical binding]; other site
761193004001	catalytic residues [active]
761193004002	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
761193004003	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193004004	SnoaL-like domain; Region: SnoaL_3; pfam13474
761193004005	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193004006	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193004007	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193004008	Peptidase family M48; Region: Peptidase_M48; pfam01435
761193004009	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
761193004010	active site
761193004011	RDD family; Region: RDD; pfam06271
761193004012	Integral membrane protein DUF95; Region: DUF95; pfam01944
761193004013	similar to  signal transduction histidine kinase; PFAM: Histidine kinase; Pentapeptide repeats (8 copies); Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: dfe:Dfer_3759 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase
761193004014	similar to pseudouridine synthase; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family; COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: dfe:Dfer_3814 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Glycine hydroxymethyltransferase
761193004015	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
761193004016	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
761193004017	dimer interface [polypeptide binding]; other site
761193004018	active site
761193004019	glycine-pyridoxal phosphate binding site [chemical binding]; other site
761193004020	folate binding site [chemical binding]; other site
761193004021	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
761193004022	RNA/DNA hybrid binding site [nucleotide binding]; other site
761193004023	active site
761193004024	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
761193004025	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
761193004026	Chain length determinant protein; Region: Wzz; cl15801
761193004027	exopolysaccharide/PEP-CTERM locus tyrosine autokinase; Region: pepcterm_TyrKin; TIGR03018
761193004028	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
761193004029	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
761193004030	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
761193004031	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193004032	binding surface
761193004033	TPR motif; other site
761193004034	Ribokinase-like subgroup C.  Found only in bacteria, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_C; cd01946
761193004035	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
761193004036	substrate binding site [chemical binding]; other site
761193004037	ATP binding site [chemical binding]; other site
761193004038	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
761193004039	dimer interface [polypeptide binding]; other site
761193004040	allosteric magnesium binding site [ion binding]; other site
761193004041	active site
761193004042	aspartate-rich active site metal binding site; other site
761193004043	Schiff base residues; other site
761193004044	Fasciclin domain; Region: Fasciclin; pfam02469
761193004045	Fasciclin domain; Region: Fasciclin; pfam02469
761193004046	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
761193004047	Transglycosylase; Region: Transgly; pfam00912
761193004048	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
761193004049	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
761193004050	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
761193004051	Divergent AAA domain; Region: AAA_4; pfam04326
761193004052	amino acid transporter; Region: 2A0306; TIGR00909
761193004053	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
761193004054	transferase 1, rSAM/selenodomain-associated; Region: glyco_like_cofC; TIGR04282
761193004055	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
761193004056	Sporulation related domain; Region: SPOR; pfam05036
761193004057	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
761193004058	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
761193004059	NADP-binding site; other site
761193004060	homotetramer interface [polypeptide binding]; other site
761193004061	substrate binding site [chemical binding]; other site
761193004062	homodimer interface [polypeptide binding]; other site
761193004063	active site
761193004064	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
761193004065	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
761193004066	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
761193004067	C-20 methyltransferase BchU; Region: C20_methyl_CrtF; TIGR02716
761193004068	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193004069	S-adenosylmethionine binding site [chemical binding]; other site
761193004070	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
761193004071	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
761193004072	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
761193004073	Uncharacterized bacterial subgroup of the N-terminal domain of Fpg (formamidopyrimidine-DNA glycosylase, MutM)_Nei  (endonuclease VIII) base-excision repair DNA glycosylases; Region: BaFpgNei_N_4; cd08976
761193004074	putative DNA binding site [nucleotide binding]; other site
761193004075	catalytic residue [active]
761193004076	putative H2TH interface [polypeptide binding]; other site
761193004077	putative catalytic residues [active]
761193004078	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
761193004079	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
761193004080	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
761193004081	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
761193004082	Ligand binding site; other site
761193004083	Putative Catalytic site; other site
761193004084	DXD motif; other site
761193004085	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193004086	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193004087	active site
761193004088	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193004089	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
761193004090	active site
761193004091	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
761193004092	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
761193004093	Trm112p-like protein; Region: Trm112p; cl01066
761193004094	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
761193004095	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193004096	S-adenosylmethionine binding site [chemical binding]; other site
761193004097	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193004098	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193004099	active site
761193004100	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193004101	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
761193004102	NAD binding site [chemical binding]; other site
761193004103	homotetramer interface [polypeptide binding]; other site
761193004104	homodimer interface [polypeptide binding]; other site
761193004105	active site
761193004106	substrate binding site [chemical binding]; other site
761193004107	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193004108	dimer interface [polypeptide binding]; other site
761193004109	phosphorylation site [posttranslational modification]
761193004110	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193004111	ATP binding site [chemical binding]; other site
761193004112	Mg2+ binding site [ion binding]; other site
761193004113	G-X-G motif; other site
761193004114	ribosomal protein L33; Region: rpl33; CHL00104
761193004115	Domain of unknown function (DUF4295); Region: DUF4295; pfam14128
761193004116	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
761193004117	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
761193004118	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
761193004119	P loop; other site
761193004120	GTP binding site [chemical binding]; other site
761193004121	Protein of unknown function (DUF1501); Region: DUF1501; pfam07394
761193004122	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
761193004123	putative active site [active]
761193004124	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193004125	Protein of unknown function (DUF1549); Region: PSCyt2; pfam07583
761193004126	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
761193004127	Protein of unknown function (DUF1553); Region: PSD1; pfam07587
761193004128	HupE / UreJ protein; Region: HupE_UreJ_2; pfam13795
761193004129	Protein of unknown function (DUF3500); Region: DUF3500; pfam12006
761193004130	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193004131	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193004132	active site
761193004133	phosphorylation site [posttranslational modification]
761193004134	intermolecular recognition site; other site
761193004135	dimerization interface [polypeptide binding]; other site
761193004136	LytTr DNA-binding domain; Region: LytTR; smart00850
761193004137	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193004138	Histidine kinase; Region: His_kinase; pfam06580
761193004139	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2828
761193004140	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
761193004141	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; Region: 2-Hacid_dh_C; pfam02826
761193004142	Domain of unknown function (DUF1932); Region: DUF1932; pfam09130
761193004143	Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684
761193004144	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
761193004145	four helix bundle protein; Region: TIGR02436
761193004146	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
761193004147	N-terminal, non-catalytic, domain of BphC_JF8, (2,3-dihydroxybiphenyl 1,2-dioxygenase) from Bacillus sp. JF8 and similar proteins; Region: BphC-JF8_N_like; cd09013
761193004148	tetramer interface [polypeptide binding]; other site
761193004149	catechol 2,3 dioxygenase; Region: catechol_2_3; TIGR03211
761193004150	C-terminal, catalytic, domain of BphC_JF8, (2,3-dihydroxybiphenyl 1,2-dioxygenase) from Bacillus sp. JF8 and similar proteins; Region: BphC-JF8_C_like; cd09014
761193004151	tetramer interface [polypeptide binding]; other site
761193004152	active site
761193004153	metal binding site [ion binding]; metal-binding site
761193004154	BNR repeat-like domain; Region: BNR_2; pfam13088
761193004155	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
761193004156	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193004157	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
761193004158	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
761193004159	PhnA protein; Region: PhnA; pfam03831
761193004160	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
761193004161	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193004162	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
761193004163	active site clefts [active]
761193004164	zinc binding site [ion binding]; other site
761193004165	dimer interface [polypeptide binding]; other site
761193004166	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl17369
761193004167	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
761193004168	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
761193004169	catalytic site [active]
761193004170	putative active site [active]
761193004171	putative substrate binding site [chemical binding]; other site
761193004172	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
761193004173	Clp amino terminal domain; Region: Clp_N; pfam02861
761193004174	Clp amino terminal domain; Region: Clp_N; pfam02861
761193004175	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193004176	Walker A motif; other site
761193004177	ATP binding site [chemical binding]; other site
761193004178	Walker B motif; other site
761193004179	arginine finger; other site
761193004180	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193004181	Walker A motif; other site
761193004182	ATP binding site [chemical binding]; other site
761193004183	Walker B motif; other site
761193004184	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
761193004185	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193004186	putative active site [active]
761193004187	Family description; Region: VCBS; pfam13517
761193004188	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193004189	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
761193004190	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
761193004191	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
761193004192	Ligand binding site; other site
761193004193	Putative Catalytic site; other site
761193004194	DXD motif; other site
761193004195	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193004196	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193004197	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193004198	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
761193004199	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193004200	active site
761193004201	Glycosyl transferase family 8; Region: Glyco_transf_8; pfam01501
761193004202	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
761193004203	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193004204	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
761193004205	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193004206	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
761193004207	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193004208	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
761193004209	Probable Catalytic site; other site
761193004210	metal-binding site
761193004211	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
761193004212	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
761193004213	putative trimer interface [polypeptide binding]; other site
761193004214	putative CoA binding site [chemical binding]; other site
761193004215	WbqC-like protein family; Region: WbqC; pfam08889
761193004216	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
761193004217	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
761193004218	inhibitor-cofactor binding pocket; inhibition site
761193004219	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193004220	catalytic residue [active]
761193004221	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
761193004222	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
761193004223	Walker A/P-loop; other site
761193004224	ATP binding site [chemical binding]; other site
761193004225	Q-loop/lid; other site
761193004226	ABC transporter signature motif; other site
761193004227	Walker B; other site
761193004228	D-loop; other site
761193004229	H-loop/switch region; other site
761193004230	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
761193004231	putative carbohydrate binding site [chemical binding]; other site
761193004232	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
761193004233	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
761193004234	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
761193004235	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
761193004236	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
761193004237	SLBB domain; Region: SLBB; pfam10531
761193004238	SLBB domain; Region: SLBB; pfam10531
761193004239	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
761193004240	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193004241	ATP binding site [chemical binding]; other site
761193004242	Mg2+ binding site [ion binding]; other site
761193004243	G-X-G motif; other site
761193004244	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of type II DNA topoisomerases (Topo II) and DNA mismatch repair (MutL/MLH1/PMS2) proteins. This transducer domain is homologous to the second...; Region: TopoII_MutL_Trans; cl02783
761193004245	ATP binding site [chemical binding]; other site
761193004246	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
761193004247	active site
761193004248	putative metal-binding site [ion binding]; other site
761193004249	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
761193004250	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
761193004251	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
761193004252	Protein of unknown function, DUF486; Region: DUF486; cl01236
761193004253	glucosamine-6-phosphate deaminase-like protein; Validated; Region: PRK02122
761193004254	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
761193004255	active site
761193004256	trimer interface [polypeptide binding]; other site
761193004257	allosteric site; other site
761193004258	active site lid [active]
761193004259	hexamer (dimer of trimers) interface [polypeptide binding]; other site
761193004260	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
761193004261	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
761193004262	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
761193004263	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
761193004264	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193004265	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
761193004266	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193004267	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
761193004268	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193004269	N-terminal plug; other site
761193004270	ligand-binding site [chemical binding]; other site
761193004271	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
761193004272	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
761193004273	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
761193004274	substrate binding site; other site
761193004275	dimer interface; other site
761193004276	membrane ATPase/protein kinase; Provisional; Region: PRK09435
761193004277	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
761193004278	Walker A; other site
761193004279	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
761193004280	active site
761193004281	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
761193004282	Transglycosylase; Region: Transgly; cl17702
761193004283	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
761193004284	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193004285	FeS/SAM binding site; other site
761193004286	HemN C-terminal domain; Region: HemN_C; pfam06969
761193004287	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193004288	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193004289	ligand binding site [chemical binding]; other site
761193004290	Predicted transcriptional regulators [Transcription]; Region: COG1695
761193004291	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
761193004292	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4877
761193004293	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
761193004294	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_2; cd03402
761193004295	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
761193004296	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
761193004297	dimer interface [polypeptide binding]; other site
761193004298	putative anticodon binding site; other site
761193004299	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
761193004300	motif 1; other site
761193004301	active site
761193004302	motif 2; other site
761193004303	motif 3; other site
761193004304	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
761193004305	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
761193004306	FAD binding pocket [chemical binding]; other site
761193004307	FAD binding motif [chemical binding]; other site
761193004308	phosphate binding motif [ion binding]; other site
761193004309	beta-alpha-beta structure motif; other site
761193004310	NAD(p) ribose binding residues [chemical binding]; other site
761193004311	NAD binding pocket [chemical binding]; other site
761193004312	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
761193004313	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193004314	catalytic loop [active]
761193004315	iron binding site [ion binding]; other site
761193004316	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
761193004317	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
761193004318	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193004319	catalytic residue [active]
761193004320	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429
761193004321	agmatinase; Region: agmatinase; TIGR01230
761193004322	Predicted flavoprotein [General function prediction only]; Region: COG0431
761193004323	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
761193004324	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193004325	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193004326	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193004327	DNA binding residues [nucleotide binding]
761193004328	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193004329	NADH(P)-binding; Region: NAD_binding_10; pfam13460
761193004330	NAD(P) binding site [chemical binding]; other site
761193004331	active site
761193004332	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193004333	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193004334	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193004335	ligand binding site [chemical binding]; other site
761193004336	flexible hinge region; other site
761193004337	4Fe-4S binding domain; Region: Fer4_5; pfam12801
761193004338	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
761193004339	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
761193004340	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
761193004341	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
761193004342	gamma subunit interface [polypeptide binding]; other site
761193004343	LBP interface [polypeptide binding]; other site
761193004344	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
761193004345	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
761193004346	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
761193004347	alpha subunit interaction interface [polypeptide binding]; other site
761193004348	Walker A motif; other site
761193004349	ATP binding site [chemical binding]; other site
761193004350	Walker B motif; other site
761193004351	inhibitor binding site; inhibition site
761193004352	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
761193004353	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
761193004354	phosphorylation site [posttranslational modification]
761193004355	dimer interface [polypeptide binding]; other site
761193004356	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193004357	ATP binding site [chemical binding]; other site
761193004358	Mg2+ binding site [ion binding]; other site
761193004359	G-X-G motif; other site
761193004360	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
761193004361	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
761193004362	tRNA; other site
761193004363	putative tRNA binding site [nucleotide binding]; other site
761193004364	putative NADP binding site [chemical binding]; other site
761193004365	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
761193004366	L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active...; Region: DmpA; cd02253
761193004367	homodimer interface [polypeptide binding]; other site
761193004368	homotetramer interface [polypeptide binding]; other site
761193004369	active site pocket [active]
761193004370	cleavage site
761193004371	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193004372	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
761193004373	malate dehydrogenase; Reviewed; Region: PRK06223
761193004374	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
761193004375	NAD(P) binding site [chemical binding]; other site
761193004376	dimer interface [polypeptide binding]; other site
761193004377	tetramer (dimer of dimers) interface [polypeptide binding]; other site
761193004378	substrate binding site [chemical binding]; other site
761193004379	hypothetical protein; Provisional; Region: PRK04081
761193004380	Glutathionylspermidine synthase preATP-grasp; Region: GSP_synth; cl00503
761193004381	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
761193004382	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
761193004383	Walker A/P-loop; other site
761193004384	ATP binding site [chemical binding]; other site
761193004385	Q-loop/lid; other site
761193004386	ABC transporter signature motif; other site
761193004387	Walker B; other site
761193004388	D-loop; other site
761193004389	H-loop/switch region; other site
761193004390	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
761193004391	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193004392	FtsX-like permease family; Region: FtsX; pfam02687
761193004393	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
761193004394	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193004395	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
761193004396	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193004397	active site
761193004398	Outer membrane efflux protein; Region: OEP; pfam02321
761193004399	Outer membrane efflux protein; Region: OEP; pfam02321
761193004400	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193004401	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
761193004402	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193004403	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
761193004404	Protein export membrane protein; Region: SecD_SecF; cl14618
761193004405	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193004406	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193004407	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193004408	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
761193004409	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
761193004410	Soluble P-type ATPase [General function prediction only]; Region: COG4087
761193004411	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193004412	binding surface
761193004413	Tetratricopeptide repeat; Region: TPR_16; pfam13432
761193004414	TPR motif; other site
761193004415	Tetratricopeptide repeat; Region: TPR_16; pfam13432
761193004416	BNR repeat-like domain; Region: BNR_2; pfam13088
761193004417	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193004418	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193004419	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193004420	ligand binding site [chemical binding]; other site
761193004421	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
761193004422	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
761193004423	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
761193004424	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
761193004425	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
761193004426	active site
761193004427	catalytic tetrad [active]
761193004428	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
761193004429	Predicted membrane protein [Function unknown]; Region: COG4325
761193004430	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
761193004431	EamA-like transporter family; Region: EamA; pfam00892
761193004432	EamA-like transporter family; Region: EamA; pfam00892
761193004433	similar to acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR006145:IPR000748; KEGG: sli:Slin_0522 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F
761193004434	similar to pseudouridine synthase Rsu; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase; InterPro IPR001387; KEGG: ate:Athe_2435 XRE family transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family
761193004435	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193004436	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193004437	non-specific DNA binding site [nucleotide binding]; other site
761193004438	salt bridge; other site
761193004439	sequence-specific DNA binding site [nucleotide binding]; other site
761193004440	SIR2-like domain; Region: SIR2_2; pfam13289
761193004441	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
761193004442	active site
761193004443	dimer interface [polypeptide binding]; other site
761193004444	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
761193004445	catalytic core [active]
761193004446	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
761193004447	CoenzymeA binding site [chemical binding]; other site
761193004448	subunit interaction site [polypeptide binding]; other site
761193004449	PHB binding site; other site
761193004450	N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also called glycogen 6-glucanohydrolase) proteins; Region: E_set_Isoamylase_like_N; cd07184
761193004451	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
761193004452	heme-binding site [chemical binding]; other site
761193004453	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
761193004454	catalytic residues [active]
761193004455	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193004456	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
761193004457	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193004458	N-terminal plug; other site
761193004459	ligand-binding site [chemical binding]; other site
761193004460	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
761193004461	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
761193004462	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
761193004463	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
761193004464	InterPro IPR000866; KEGG: sli:Slin_6023 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen
761193004465	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
761193004466	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193004467	putative catalytic residue [active]
761193004468	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193004469	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
761193004470	Ligand binding site; other site
761193004471	Putative Catalytic site; other site
761193004472	DXD motif; other site
761193004473	The MopB_1 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members belong to...; Region: MopB_1; cd02762
761193004474	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
761193004475	putative [Fe4-S4] binding site [ion binding]; other site
761193004476	putative molybdopterin cofactor binding site [chemical binding]; other site
761193004477	The MopB_CT_1 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is of the...; Region: MopB_CT_1; cd02782
761193004478	putative molybdopterin cofactor binding site; other site
761193004479	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
761193004480	LysE type translocator; Region: LysE; cl00565
761193004481	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
761193004482	classical (c) SDRs; Region: SDR_c; cd05233
761193004483	NAD(P) binding site [chemical binding]; other site
761193004484	active site
761193004485	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
761193004486	Sodium Bile acid symporter family; Region: SBF; cl17470
761193004487	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
761193004488	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
761193004489	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
761193004490	catalytic site [active]
761193004491	subunit interface [polypeptide binding]; other site
761193004492	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
761193004493	Uncharacterized conserved protein [Function unknown]; Region: COG3743
761193004494	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
761193004495	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
761193004496	alphaNTD - beta interaction site [polypeptide binding]; other site
761193004497	alphaNTD homodimer interface [polypeptide binding]; other site
761193004498	alphaNTD - beta' interaction site [polypeptide binding]; other site
761193004499	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
761193004500	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
761193004501	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
761193004502	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
761193004503	RNA binding surface [nucleotide binding]; other site
761193004504	30S ribosomal protein S11; Validated; Region: PRK05309
761193004505	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
761193004506	30S ribosomal protein S13; Region: bact_S13; TIGR03631
761193004507	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
761193004508	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
761193004509	rRNA binding site [nucleotide binding]; other site
761193004510	predicted 30S ribosome binding site; other site
761193004511	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
761193004512	active site
761193004513	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
761193004514	SecY translocase; Region: SecY; pfam00344
761193004515	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
761193004516	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
761193004517	23S rRNA binding site [nucleotide binding]; other site
761193004518	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
761193004519	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
761193004520	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
761193004521	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
761193004522	5S rRNA interface [nucleotide binding]; other site
761193004523	23S rRNA interface [nucleotide binding]; other site
761193004524	L5 interface [polypeptide binding]; other site
761193004525	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
761193004526	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
761193004527	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
761193004528	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
761193004529	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
761193004530	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
761193004531	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
761193004532	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
761193004533	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
761193004534	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
761193004535	RNA binding site [nucleotide binding]; other site
761193004536	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
761193004537	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
761193004538	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
761193004539	23S rRNA interface [nucleotide binding]; other site
761193004540	putative translocon interaction site; other site
761193004541	signal recognition particle (SRP54) interaction site; other site
761193004542	L23 interface [polypeptide binding]; other site
761193004543	trigger factor interaction site; other site
761193004544	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
761193004545	23S rRNA interface [nucleotide binding]; other site
761193004546	5S rRNA interface [nucleotide binding]; other site
761193004547	putative antibiotic binding site [chemical binding]; other site
761193004548	L25 interface [polypeptide binding]; other site
761193004549	L27 interface [polypeptide binding]; other site
761193004550	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
761193004551	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
761193004552	G-X-X-G motif; other site
761193004553	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
761193004554	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
761193004555	putative translocon binding site; other site
761193004556	protein-rRNA interface [nucleotide binding]; other site
761193004557	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
761193004558	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
761193004559	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
761193004560	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
761193004561	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
761193004562	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
761193004563	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
761193004564	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
761193004565	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
761193004566	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
761193004567	active site
761193004568	substrate binding site [chemical binding]; other site
761193004569	cosubstrate binding site; other site
761193004570	catalytic site [active]
761193004571	Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) and related proteins; solute binding domain; Region: SLC5sbd_vSGLT; cd10325
761193004572	putative transporter; Provisional; Region: PRK10484
761193004573	Na binding site [ion binding]; other site
761193004574	substrate binding site [chemical binding]; other site
761193004575	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
761193004576	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
761193004577	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
761193004578	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; cl17194
761193004579	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
761193004580	Protein of unknown function (DUF2795); Region: DUF2795; pfam11387
761193004581	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
761193004582	alpha-glucosidase; Provisional; Region: PRK10137
761193004583	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
761193004584	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
761193004585	Neutral/alkaline non-lysosomal ceramidase; Region: Ceramidase_alk; cl04712
761193004586	3-methylcrotonyl-CoA carboxylase, beta chain; Region: PLN02820
761193004587	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193004588	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
761193004589	active site
761193004590	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
761193004591	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193004592	putative ADP-binding pocket [chemical binding]; other site
761193004593	Bacterial sugar transferase; Region: Bac_transf; pfam02397
761193004594	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
761193004595	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
761193004596	putative trimer interface [polypeptide binding]; other site
761193004597	putative CoA binding site [chemical binding]; other site
761193004598	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
761193004599	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193004600	S-adenosylmethionine binding site [chemical binding]; other site
761193004601	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193004602	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
761193004603	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
761193004604	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
761193004605	Chromate transporter; Region: Chromate_transp; pfam02417
761193004606	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
761193004607	Chromate transporter; Region: Chromate_transp; pfam02417
761193004608	Peptidase S46; Region: Peptidase_S46; pfam10459
761193004609	Peptidase S7, Flavivirus NS3 serine protease; Region: Peptidase_S7; pfam00949
761193004610	GTP-binding protein Der; Reviewed; Region: PRK00093
761193004611	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
761193004612	G1 box; other site
761193004613	GTP/Mg2+ binding site [chemical binding]; other site
761193004614	Switch I region; other site
761193004615	G2 box; other site
761193004616	Switch II region; other site
761193004617	G3 box; other site
761193004618	G4 box; other site
761193004619	G5 box; other site
761193004620	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
761193004621	G1 box; other site
761193004622	GTP/Mg2+ binding site [chemical binding]; other site
761193004623	Switch I region; other site
761193004624	G2 box; other site
761193004625	G3 box; other site
761193004626	Switch II region; other site
761193004627	G4 box; other site
761193004628	G5 box; other site
761193004629	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
761193004630	four helix bundle protein; Region: TIGR02436
761193004631	GTPase Era; Reviewed; Region: era; PRK00089
761193004632	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
761193004633	G1 box; other site
761193004634	GTP/Mg2+ binding site [chemical binding]; other site
761193004635	Switch I region; other site
761193004636	G2 box; other site
761193004637	Switch II region; other site
761193004638	G3 box; other site
761193004639	G4 box; other site
761193004640	G5 box; other site
761193004641	KH domain; Region: KH_2; pfam07650
761193004642	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
761193004643	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
761193004644	Transposase; Region: DDE_Tnp_ISL3; pfam01610
761193004645	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193004646	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193004647	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
761193004648	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193004649	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193004650	catalytic residue [active]
761193004651	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193004652	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
761193004653	Methyltransferase domain; Region: Methyltransf_23; pfam13489
761193004654	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193004655	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193004656	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193004657	Acetyl esterase (deacetylase) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3458
761193004658	PspC domain; Region: PspC; pfam04024
761193004659	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193004660	active site
761193004661	GRAS family transcription factor; Region: GRAS; pfam03514
761193004662	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4634
761193004663	Protein of unknown function (DUF433); Region: DUF433; pfam04255
761193004664	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
761193004665	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
761193004666	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
761193004667	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
761193004668	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
761193004669	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
761193004670	substrate binding site [chemical binding]; other site
761193004671	oxyanion hole (OAH) forming residues; other site
761193004672	trimer interface [polypeptide binding]; other site
761193004673	peptide chain release factor 1; Validated; Region: prfA; PRK00591
761193004674	This domain is found in peptide chain release factors; Region: PCRF; smart00937
761193004675	RF-1 domain; Region: RF-1; pfam00472
761193004676	Protein of unknown function (DUF1271); Region: DUF1271; pfam06902
761193004677	CDGSH-type zinc finger. Function unknown; Region: ZnF_CDGSH; smart00704
761193004678	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
761193004679	This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990
761193004680	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193004681	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193004682	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193004683	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193004684	ligand binding site [chemical binding]; other site
761193004685	This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins.  sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa; Region: ACD_sHsps_p23-like; cd00298
761193004686	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
761193004687	active site
761193004688	Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418
761193004689	acyl-CoA dehydrogenase; Provisional; Region: PTZ00456
761193004690	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
761193004691	active site
761193004692	Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806
761193004693	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
761193004694	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193004695	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
761193004696	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193004697	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193004698	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
761193004699	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193004700	catalytic loop [active]
761193004701	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cl00159
761193004702	iron binding site [ion binding]; other site
761193004703	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
761193004704	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
761193004705	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_1; cd01832
761193004706	active site
761193004707	catalytic triad [active]
761193004708	oxyanion hole [active]
761193004709	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
761193004710	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
761193004711	putative dimer interface [polypeptide binding]; other site
761193004712	putative anticodon binding site; other site
761193004713	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
761193004714	homodimer interface [polypeptide binding]; other site
761193004715	motif 1; other site
761193004716	motif 2; other site
761193004717	active site
761193004718	motif 3; other site
761193004719	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
761193004720	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062
761193004721	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
761193004722	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
761193004723	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
761193004724	Glycosyl hydrolase family 43; Region: GH43_3; cd08982
761193004725	active site
761193004726	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
761193004727	sugar binding site [chemical binding]; other site
761193004728	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
761193004729	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
761193004730	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
761193004731	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
761193004732	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
761193004733	Mg++ binding site [ion binding]; other site
761193004734	putative catalytic motif [active]
761193004735	putative substrate binding site [chemical binding]; other site
761193004736	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
761193004737	catalytic core [active]
761193004738	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
761193004739	Bacterial Ig-like domain; Region: Big_5; pfam13205
761193004740	Middle domain of rhamnogalacturonan lyase, a family 4 polysaccharide lyase; Region: RGL4_M; cd10316
761193004741	Uncharacterized protein conserved in bacteria (DUF2141); Region: DUF2141; cl01930
761193004742	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
761193004743	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
761193004744	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
761193004745	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
761193004746	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
761193004747	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193004748	FeS/SAM binding site; other site
761193004749	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
761193004750	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
761193004751	RNA polymerases M/15 Kd subunit; Region: RNA_POL_M_15KD; cl02717
761193004752	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
761193004753	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
761193004754	A new structural DNA glycosylase; Region: AlkD_like; cd06561
761193004755	active site
761193004756	cell division protein FtsZ; Validated; Region: PRK09330
761193004757	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
761193004758	nucleotide binding site [chemical binding]; other site
761193004759	SulA interaction site; other site
761193004760	cell division protein FtsA; Region: ftsA; TIGR01174
761193004761	Cell division protein FtsA; Region: FtsA; smart00842
761193004762	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
761193004763	Cell division protein FtsA; Region: FtsA; pfam14450
761193004764	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
761193004765	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
761193004766	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
761193004767	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
761193004768	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
761193004769	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
761193004770	active site
761193004771	homodimer interface [polypeptide binding]; other site
761193004772	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
761193004773	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
761193004774	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
761193004775	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
761193004776	Predicted membrane protein (DUF2231); Region: DUF2231; cl01730
761193004777	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193004778	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
761193004779	Substrate binding site [chemical binding]; other site
761193004780	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
761193004781	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
761193004782	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
761193004783	lipoyl attachment site [posttranslational modification]; other site
761193004784	dihydroorotase; Validated; Region: pyrC; PRK09357
761193004785	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193004786	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
761193004787	active site
761193004788	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
761193004789	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
761193004790	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193004791	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193004792	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193004793	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
761193004794	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
761193004795	YARHG domain; Region: YARHG; pfam13308
761193004796	peptide chain release factor 2; Validated; Region: prfB; PRK00578
761193004797	This domain is found in peptide chain release factors; Region: PCRF; smart00937
761193004798	RF-1 domain; Region: RF-1; pfam00472
761193004799	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193004800	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193004801	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193004802	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193004803	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193004804	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
761193004805	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
761193004806	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
761193004807	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193004808	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
761193004809	active site
761193004810	HupE / UreJ protein; Region: HupE_UreJ_2; pfam13795
761193004811	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
761193004812	Zn binding site [ion binding]; other site
761193004813	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
761193004814	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193004815	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193004816	catalytic residues [active]
761193004817	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
761193004818	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
761193004819	putative metal binding site [ion binding]; other site
761193004820	Serpin (serine protease inhibitor); Region: Serpin; pfam00079
761193004821	serpin-like protein; Provisional; Region: PHA02660
761193004822	reactive center loop; other site
761193004823	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193004824	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193004825	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193004826	DNA binding residues [nucleotide binding]
761193004827	elongation factor Tu; Reviewed; Region: PRK12735
761193004828	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
761193004829	G1 box; other site
761193004830	GEF interaction site [polypeptide binding]; other site
761193004831	GTP/Mg2+ binding site [chemical binding]; other site
761193004832	Switch I region; other site
761193004833	G2 box; other site
761193004834	G3 box; other site
761193004835	Switch II region; other site
761193004836	G4 box; other site
761193004837	G5 box; other site
761193004838	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
761193004839	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
761193004840	Antibiotic Binding Site [chemical binding]; other site
761193004841	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
761193004842	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
761193004843	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
761193004844	Histidine kinase; Region: HisKA_3; pfam07730
761193004845	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193004846	ATP binding site [chemical binding]; other site
761193004847	Mg2+ binding site [ion binding]; other site
761193004848	G-X-G motif; other site
761193004849	H+ Antiporter protein; Region: 2A0121; TIGR00900
761193004850	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193004851	putative substrate translocation pore; other site
761193004852	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
761193004853	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
761193004854	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
761193004855	putative homodimer interface [polypeptide binding]; other site
761193004856	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
761193004857	heterodimer interface [polypeptide binding]; other site
761193004858	homodimer interface [polypeptide binding]; other site
761193004859	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
761193004860	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
761193004861	23S rRNA interface [nucleotide binding]; other site
761193004862	L7/L12 interface [polypeptide binding]; other site
761193004863	putative thiostrepton binding site; other site
761193004864	L25 interface [polypeptide binding]; other site
761193004865	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
761193004866	mRNA/rRNA interface [nucleotide binding]; other site
761193004867	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
761193004868	23S rRNA interface [nucleotide binding]; other site
761193004869	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
761193004870	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
761193004871	core dimer interface [polypeptide binding]; other site
761193004872	peripheral dimer interface [polypeptide binding]; other site
761193004873	L10 interface [polypeptide binding]; other site
761193004874	L11 interface [polypeptide binding]; other site
761193004875	putative EF-Tu interaction site [polypeptide binding]; other site
761193004876	putative EF-G interaction site [polypeptide binding]; other site
761193004877	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
761193004878	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
761193004879	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
761193004880	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
761193004881	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
761193004882	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
761193004883	RPB3 interaction site [polypeptide binding]; other site
761193004884	RPB1 interaction site [polypeptide binding]; other site
761193004885	RPB11 interaction site [polypeptide binding]; other site
761193004886	RPB10 interaction site [polypeptide binding]; other site
761193004887	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
761193004888	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
761193004889	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
761193004890	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
761193004891	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
761193004892	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
761193004893	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
761193004894	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
761193004895	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193004896	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
761193004897	DNA binding site [nucleotide binding]
761193004898	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
761193004899	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
761193004900	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
761193004901	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
761193004902	active site
761193004903	Fn3 associated; Region: Fn3_assoc; pfam13287
761193004904	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
761193004905	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193004906	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193004907	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
761193004908	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193004909	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193004910	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
761193004911	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193004912	Walker A/P-loop; other site
761193004913	ATP binding site [chemical binding]; other site
761193004914	Q-loop/lid; other site
761193004915	ABC transporter signature motif; other site
761193004916	Walker B; other site
761193004917	D-loop; other site
761193004918	H-loop/switch region; other site
761193004919	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193004920	Walker A/P-loop; other site
761193004921	ATP binding site [chemical binding]; other site
761193004922	Q-loop/lid; other site
761193004923	ABC transporter signature motif; other site
761193004924	Walker B; other site
761193004925	D-loop; other site
761193004926	H-loop/switch region; other site
761193004927	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
761193004928	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
761193004929	active site
761193004930	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
761193004931	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
761193004932	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193004933	Interdomain contacts; other site
761193004934	Cytokine receptor motif; other site
761193004935	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193004936	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193004937	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193004938	active site
761193004939	phosphorylation site [posttranslational modification]
761193004940	intermolecular recognition site; other site
761193004941	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
761193004942	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
761193004943	putative active site [active]
761193004944	putative NTP binding site [chemical binding]; other site
761193004945	putative nucleic acid binding site [nucleotide binding]; other site
761193004946	AAA domain; Region: AAA_30; pfam13604
761193004947	Family description; Region: UvrD_C_2; pfam13538
761193004948	Predicted transcriptional regulator [Transcription]; Region: COG2378
761193004949	HTH domain; Region: HTH_11; cl17392
761193004950	WYL domain; Region: WYL; pfam13280
761193004951	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
761193004952	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
761193004953	Protein of unknown function (DUF433); Region: DUF433; pfam04255
761193004954	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
761193004955	Zn binding site [ion binding]; other site
761193004956	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
761193004957	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
761193004958	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
761193004959	Family description; Region: VCBS; pfam13517
761193004960	Family description; Region: VCBS; pfam13517
761193004961	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193004962	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
761193004963	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
761193004964	active site
761193004965	nucleophile elbow; other site
761193004966	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
761193004967	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193004968	motif II; other site
761193004969	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
761193004970	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
761193004971	MOSC domain; Region: MOSC; pfam03473
761193004972	phytoene desaturase; Region: crtI_fam; TIGR02734
761193004973	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193004974	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
761193004975	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
761193004976	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
761193004977	NAD(P) binding site [chemical binding]; other site
761193004978	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
761193004979	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193004980	FeS/SAM binding site; other site
761193004981	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
761193004982	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dam; COG0338
761193004983	Domain of unknown function DUF87; Region: DUF87; pfam01935
761193004984	Protein of unknown function (DUF3037); Region: DUF3037; pfam11236
761193004985	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
761193004986	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
761193004987	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193004988	Uncharacterized ACR, COG1430; Region: DUF192; pfam02643
761193004989	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
761193004990	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
761193004991	active site
761193004992	HIGH motif; other site
761193004993	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
761193004994	KMSKS motif; other site
761193004995	This DALR domain is found in cysteinyl-tRNA-synthetases; Region: DALR_2; smart00840
761193004996	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
761193004997	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
761193004998	ATP-binding site [chemical binding]; other site
761193004999	Sugar specificity; other site
761193005000	Pyrimidine base specificity; other site
761193005001	PspC domain; Region: PspC; pfam04024
761193005002	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
761193005003	DNA-binding site [nucleotide binding]; DNA binding site
761193005004	RNA-binding motif; other site
761193005005	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193005006	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193005007	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193005008	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
761193005009	MoxR-like ATPases [General function prediction only]; Region: COG0714
761193005010	ATPase family associated with various cellular activities (AAA); Region: AAA_3; pfam07726
761193005011	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
761193005012	Cytochrome c; Region: Cytochrom_C; cl11414
761193005013	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193005014	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193005015	putative substrate translocation pore; other site
761193005016	RecX family; Region: RecX; pfam02631
761193005017	Protein of unknown function (DUF433); Region: DUF433; pfam04255
761193005018	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4634
761193005019	Argininosuccinate lyase [Amino acid transport and metabolism]; Region: ArgH; COG0165
761193005020	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
761193005021	active sites [active]
761193005022	tetramer interface [polypeptide binding]; other site
761193005023	GxxExxY protein; Region: GxxExxY; TIGR04256
761193005024	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
761193005025	Zn binding site [ion binding]; other site
761193005026	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
761193005027	NHAD transporter family protein; Provisional; Region: PLN00137; cl17324
761193005028	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
761193005029	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
761193005030	substrate binding site; other site
761193005031	tetramer interface; other site
761193005032	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
761193005033	Lumazine binding domain; Region: Lum_binding; pfam00677
761193005034	Lumazine binding domain; Region: Lum_binding; pfam00677
761193005035	GxxExxY protein; Region: GxxExxY; TIGR04256
761193005036	Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac2_AmyA; cd11316
761193005037	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
761193005038	Ca binding site [ion binding]; other site
761193005039	active site
761193005040	catalytic site [active]
761193005041	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
761193005042	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
761193005043	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
761193005044	TRAM domain; Region: TRAM; cl01282
761193005045	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193005046	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
761193005047	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
761193005048	active site
761193005049	trimer interface [polypeptide binding]; other site
761193005050	allosteric site; other site
761193005051	active site lid [active]
761193005052	hexamer (dimer of trimers) interface [polypeptide binding]; other site
761193005053	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
761193005054	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
761193005055	active site
761193005056	dimer interface [polypeptide binding]; other site
761193005057	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193005058	glucose/galactose transporter; Region: gluP; TIGR01272
761193005059	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193005060	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193005061	Neutral/alkaline non-lysosomal ceramidase; Region: Ceramidase_alk; cl04712
761193005062	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
761193005063	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
761193005064	inhibitor-cofactor binding pocket; inhibition site
761193005065	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193005066	catalytic residue [active]
761193005067	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193005068	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
761193005069	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193005070	NAD(P) binding site [chemical binding]; other site
761193005071	active site
761193005072	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193005073	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193005074	Bax inhibitor 1 like; Region: BaxI_1; cl17691
761193005075	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193005076	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193005077	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193005078	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193005079	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
761193005080	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193005081	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
761193005082	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
761193005083	active site
761193005084	dimer interface [polypeptide binding]; other site
761193005085	MG2 domain; Region: A2M_N; pfam01835
761193005086	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193005087	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193005088	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193005089	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193005090	threonyl-tRNA synthetase; Region: thrS; TIGR00418
761193005091	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193005092	Amidohydrolase; Region: Amidohydro_5; pfam13594
761193005093	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193005094	Transcriptional regulators [Transcription]; Region: PurR; COG1609
761193005095	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
761193005096	DNA binding site [nucleotide binding]
761193005097	domain linker motif; other site
761193005098	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
761193005099	dimerization interface [polypeptide binding]; other site
761193005100	ligand binding site [chemical binding]; other site
761193005101	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193005102	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193005103	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193005104	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193005105	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193005106	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
761193005107	Right handed beta helix region; Region: Beta_helix; pfam13229
761193005108	Calx-beta domain; Region: Calx-beta; cl02522
761193005109	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005110	Glycosyl hydrolases related to GH101 family; Region: GHL; pfam11308
761193005111	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
761193005112	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193005113	NAD(P) binding site [chemical binding]; other site
761193005114	active site
761193005115	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
761193005116	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193005117	putative substrate translocation pore; other site
761193005118	COGs: COG3415 Transposase and inactivated derivatives; InterPro IPR001523; KEGG: sli:Slin_5275 transposase; PFAM: Paired box protein, N-terminal; SPTR: Transposase and inactivated derivatives-like protein; manually curated
761193005119	Homeodomain-like domain; Region: HTH_23; pfam13384
761193005120	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193005121	Homeodomain-like domain; Region: HTH_32; pfam13565
761193005122	Winged helix-turn helix; Region: HTH_33; pfam13592
761193005123	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193005124	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193005125	COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: phe:Phep_2596 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein
761193005126	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
761193005127	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
761193005128	galactonate dehydratase; Provisional; Region: PRK14017
761193005129	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
761193005130	active site pocket [active]
761193005131	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
761193005132	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
761193005133	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
761193005134	Bacterial long-chain fatty acid CoA synthetase (LC-FACS), including Marinobacter hydrocarbonoclasticus isoprenoid Coenzyme A synthetase; Region: LC_FACS_bac; cd05932
761193005135	acyl-activating enzyme (AAE) consensus motif; other site
761193005136	putative AMP binding site [chemical binding]; other site
761193005137	putative active site [active]
761193005138	putative CoA binding site [chemical binding]; other site
761193005139	COGs: COG0174 Glutamine synthetase; InterPro IPR008146; KEGG: dfe:Dfer_4670 glutamine synthetase catalytic region; PFAM: Glutamine synthetase, catalytic region; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase catalytic region
761193005140	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
761193005141	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
761193005142	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
761193005143	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
761193005144	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
761193005145	lipoprotein signal peptidase; Provisional; Region: PRK14788
761193005146	lipoprotein signal peptidase; Provisional; Region: PRK14787
761193005147	proline dehydrogenase; Region: PLN02681
761193005148	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
761193005149	Chorismate mutase type II; Region: CM_2; smart00830
761193005150	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193005151	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193005152	DNA binding site [nucleotide binding]
761193005153	YceI-like domain; Region: YceI; pfam04264
761193005154	KEGG: sli:Slin_2356 hypothetical protein; SPTR:  uncharacterized protein
761193005155	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005156	FtsX-like permease family; Region: FtsX; pfam02687
761193005157	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005158	FtsX-like permease family; Region: FtsX; pfam02687
761193005159	Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the...; Region: KAZAL_FS; cd00104
761193005160	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005161	FtsX-like permease family; Region: FtsX; pfam02687
761193005162	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005163	FtsX-like permease family; Region: FtsX; pfam02687
761193005164	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005165	FtsX-like permease family; Region: FtsX; pfam02687
761193005166	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005167	FtsX-like permease family; Region: FtsX; pfam02687
761193005168	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
761193005169	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193005170	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193005171	ligand binding site [chemical binding]; other site
761193005172	InterPro IPR003838; KEGG: rbi:RB2501_00531  FtsX-related transmembrane transport protein; PFAM: Protein of unknown function DUF214, permase predicted; SPTR:  FtsX-related transmembrane transport protein
761193005173	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005174	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005175	FtsX-like permease family; Region: FtsX; pfam02687
761193005176	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005177	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005178	FtsX-like permease family; Region: FtsX; pfam02687
761193005179	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005180	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005181	FtsX-like permease family; Region: FtsX; pfam02687
761193005182	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005183	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005184	FtsX-like permease family; Region: FtsX; pfam02687
761193005185	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005186	FtsX-like permease family; Region: FtsX; pfam02687
761193005187	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005188	FtsX-like permease family; Region: FtsX; pfam02687
761193005189	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005190	FtsX-like permease family; Region: FtsX; pfam02687
761193005191	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005192	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005193	FtsX-like permease family; Region: FtsX; pfam02687
761193005194	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005195	FtsX-like permease family; Region: FtsX; pfam02687
761193005196	FtsX-like permease family; Region: FtsX; pfam02687
761193005197	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005198	FtsX-like permease family; Region: FtsX; pfam02687
761193005199	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005200	FtsX-like permease family; Region: FtsX; pfam02687
761193005201	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005202	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005203	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005204	FtsX-like permease family; Region: FtsX; pfam02687
761193005205	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
761193005206	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
761193005207	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
761193005208	active site
761193005209	Zn binding site [ion binding]; other site
761193005210	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193005211	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193005212	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193005213	Methyltransferase domain; Region: Methyltransf_23; pfam13489
761193005214	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193005215	S-adenosylmethionine binding site [chemical binding]; other site
761193005216	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
761193005217	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005218	FtsX-like permease family; Region: FtsX; pfam02687
761193005219	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005220	FtsX-like permease family; Region: FtsX; pfam02687
761193005221	Transcriptional regulator PadR-like family; Region: PadR; cl17335
761193005222	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193005223	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005224	FtsX-like permease family; Region: FtsX; pfam02687
761193005225	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005226	FtsX-like permease family; Region: FtsX; pfam02687
761193005227	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005228	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005229	FtsX-like permease family; Region: FtsX; pfam02687
761193005230	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005231	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005232	FtsX-like permease family; Region: FtsX; pfam02687
761193005233	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005234	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005235	FtsX-like permease family; Region: FtsX; pfam02687
761193005236	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193005237	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005238	FtsX-like permease family; Region: FtsX; pfam02687
761193005239	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
761193005240	additional DNA contacts [nucleotide binding]; other site
761193005241	mismatch recognition site; other site
761193005242	active site
761193005243	zinc binding site [ion binding]; other site
761193005244	DNA intercalation site [nucleotide binding]; other site
761193005245	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005246	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005247	FtsX-like permease family; Region: FtsX; pfam02687
761193005248	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
761193005249	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
761193005250	Walker A/P-loop; other site
761193005251	ATP binding site [chemical binding]; other site
761193005252	Q-loop/lid; other site
761193005253	ABC transporter signature motif; other site
761193005254	Walker B; other site
761193005255	D-loop; other site
761193005256	H-loop/switch region; other site
761193005257	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
761193005258	four helix bundle protein; Region: TIGR02436
761193005259	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193005260	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193005261	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193005262	Response regulator receiver domain; Region: Response_reg; pfam00072
761193005263	active site
761193005264	phosphorylation site [posttranslational modification]
761193005265	intermolecular recognition site; other site
761193005266	dimerization interface [polypeptide binding]; other site
761193005267	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
761193005268	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193005269	Walker A motif; other site
761193005270	ATP binding site [chemical binding]; other site
761193005271	Walker B motif; other site
761193005272	arginine finger; other site
761193005273	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
761193005274	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193005275	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193005276	ATP binding site [chemical binding]; other site
761193005277	Mg2+ binding site [ion binding]; other site
761193005278	G-X-G motif; other site
761193005279	Protein of unknown function (DUF952); Region: DUF952; pfam06108
761193005280	Integral membrane protein TerC family; Region: TerC; cl10468
761193005281	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193005282	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
761193005283	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
761193005284	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193005285	Walker A motif; other site
761193005286	ATP binding site [chemical binding]; other site
761193005287	Walker B motif; other site
761193005288	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
761193005289	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
761193005290	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193005291	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
761193005292	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
761193005293	putative active site [active]
761193005294	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193005295	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193005296	Walker A/P-loop; other site
761193005297	ATP binding site [chemical binding]; other site
761193005298	Q-loop/lid; other site
761193005299	ABC transporter signature motif; other site
761193005300	Walker B; other site
761193005301	D-loop; other site
761193005302	H-loop/switch region; other site
761193005303	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
761193005304	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
761193005305	SPASM domain peptide maturase, grasp-with-spasm system; Region: SPASM_w_grasp; TIGR04193
761193005306	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
761193005307	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193005308	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193005309	salt bridge; other site
761193005310	non-specific DNA binding site [nucleotide binding]; other site
761193005311	sequence-specific DNA binding site [nucleotide binding]; other site
761193005312	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
761193005313	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
761193005314	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
761193005315	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
761193005316	nucleoside/Zn binding site; other site
761193005317	dimer interface [polypeptide binding]; other site
761193005318	catalytic motif [active]
761193005319	acyl carrier protein; Provisional; Region: acpP; PRK00982
761193005320	glycogen branching enzyme; Provisional; Region: PRK12313
761193005321	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
761193005322	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
761193005323	active site
761193005324	catalytic site [active]
761193005325	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
761193005326	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
761193005327	COGs: COG2234 aminopeptidase; InterPro IPR007484; KEGG: sli:Slin_2430 peptidase M28; PFAM: Peptidase M28; SPTR: Peptidase M28
761193005328	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193005329	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193005330	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193005331	metal binding site [ion binding]; metal-binding site
761193005332	thiamine monophosphate kinase; Provisional; Region: PRK05731
761193005333	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
761193005334	ATP binding site [chemical binding]; other site
761193005335	dimerization interface [polypeptide binding]; other site
761193005336	methionine sulfoxide reductase A; Provisional; Region: PRK14054
761193005337	Domain of unknown function (DUF3291); Region: DUF3291; pfam11695
761193005338	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
761193005339	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
761193005340	Walker A/P-loop; other site
761193005341	ATP binding site [chemical binding]; other site
761193005342	Q-loop/lid; other site
761193005343	ABC transporter signature motif; other site
761193005344	Walker B; other site
761193005345	D-loop; other site
761193005346	H-loop/switch region; other site
761193005347	Outer membrane efflux protein; Region: OEP; pfam02321
761193005348	Outer membrane efflux protein; Region: OEP; pfam02321
761193005349	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
761193005350	kynureninase; Region: kynureninase; TIGR01814
761193005351	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193005352	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193005353	catalytic residue [active]
761193005354	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
761193005355	catalytic residues [active]
761193005356	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193005357	PA14 domain; Region: PA14; cl08459
761193005358	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005359	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
761193005360	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
761193005361	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193005362	Beta-lactamase; Region: Beta-lactamase; cl17358
761193005363	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193005364	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
761193005365	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193005366	Protein of unknown function (DUF3500); Region: DUF3500; pfam12006
761193005367	parallel beta-helix repeat-containing protein; Region: beta_helix_1; TIGR03805
761193005368	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
761193005369	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
761193005370	homopentamer interface [polypeptide binding]; other site
761193005371	active site
761193005372	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
761193005373	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
761193005374	putative active site [active]
761193005375	oxyanion strand; other site
761193005376	catalytic triad [active]
761193005377	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
761193005378	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193005379	active site residue [active]
761193005380	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193005381	S-adenosylmethionine binding site [chemical binding]; other site
761193005382	dihydroorotase; Reviewed; Region: PRK09236
761193005383	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193005384	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
761193005385	active site
761193005386	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
761193005387	2-enoyl thioester reductase-like; Region: ETR_like; cd05282
761193005388	NADP binding site [chemical binding]; other site
761193005389	dimer interface [polypeptide binding]; other site
761193005390	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
761193005391	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
761193005392	putative acyl-acceptor binding pocket; other site
761193005393	RNA polymerase sigma factor; Provisional; Region: PRK12513
761193005394	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193005395	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193005396	DNA binding residues [nucleotide binding]
761193005397	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
761193005398	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
761193005399	catalytic residues [active]
761193005400	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005401	binding surface
761193005402	TPR motif; other site
761193005403	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005404	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005405	binding surface
761193005406	TPR motif; other site
761193005407	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005408	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005409	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005410	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005411	binding surface
761193005412	TPR motif; other site
761193005413	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005414	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005415	binding surface
761193005416	TPR motif; other site
761193005417	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005418	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005419	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005420	binding surface
761193005421	TPR motif; other site
761193005422	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005423	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193005424	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
761193005425	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
761193005426	MutS domain III; Region: MutS_III; pfam05192
761193005427	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193005428	Walker A/P-loop; other site
761193005429	ATP binding site [chemical binding]; other site
761193005430	Q-loop/lid; other site
761193005431	ABC transporter signature motif; other site
761193005432	Walker B; other site
761193005433	D-loop; other site
761193005434	H-loop/switch region; other site
761193005435	Smr domain; Region: Smr; pfam01713
761193005436	Protein of unknown function (DUF819); Region: DUF819; cl02317
761193005437	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
761193005438	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193005439	FtsX-like permease family; Region: FtsX; pfam02687
761193005440	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
761193005441	Ligand Binding Site [chemical binding]; other site
761193005442	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
761193005443	Ligand Binding Site [chemical binding]; other site
761193005444	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193005445	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
761193005446	dimerization interface [polypeptide binding]; other site
761193005447	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193005448	dimer interface [polypeptide binding]; other site
761193005449	phosphorylation site [posttranslational modification]
761193005450	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193005451	ATP binding site [chemical binding]; other site
761193005452	Mg2+ binding site [ion binding]; other site
761193005453	G-X-G motif; other site
761193005454	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
761193005455	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005456	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
761193005457	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
761193005458	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
761193005459	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193005460	Uncharacterized ACR, COG1678; Region: DUF179; pfam02622
761193005461	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_IV; cd01994
761193005462	Ligand Binding Site [chemical binding]; other site
761193005463	InterPro IPR000620; KEGG: sli:Slin_2955 hypothetical protein; PFAM: Protein of unknown function DUF6, transmembrane; SPTR:  uncharacterized protein
761193005464	EamA-like transporter family; Region: EamA; pfam00892
761193005465	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
761193005466	EamA-like transporter family; Region: EamA; pfam00892
761193005467	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193005468	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: alt_bact_glmU; TIGR03991
761193005469	Sugar nucleotidyl transferase; Region: NTP_transf_4; pfam13562
761193005470	Uncharacterized proteins, Left-handed parallel beta-Helix (LbH) domain: Members in this group are uncharacterized bacterial proteins containing a LbH domain with multiple turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif...; Region: LbH_unknown; cd05635
761193005471	altronate oxidoreductase; Provisional; Region: PRK03643
761193005472	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
761193005473	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
761193005474	Protein of unknown function (DUF1684); Region: DUF1684; pfam07920
761193005475	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
761193005476	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
761193005477	putative tRNA-binding site [nucleotide binding]; other site
761193005478	B3/4 domain; Region: B3_4; pfam03483
761193005479	tRNA synthetase B5 domain; Region: B5; pfam03484
761193005480	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
761193005481	dimer interface [polypeptide binding]; other site
761193005482	motif 1; other site
761193005483	motif 3; other site
761193005484	motif 2; other site
761193005485	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
761193005486	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
761193005487	phosphodiesterase; Provisional; Region: PRK12704
761193005488	KH domain; Region: KH_1; pfam00013
761193005489	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
761193005490	Zn2+ binding site [ion binding]; other site
761193005491	Mg2+ binding site [ion binding]; other site
761193005492	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
761193005493	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
761193005494	C-terminal peptidase (prc); Region: prc; TIGR00225
761193005495	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
761193005496	protein binding site [polypeptide binding]; other site
761193005497	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
761193005498	Catalytic dyad [active]
761193005499	DNA polymerase I; Provisional; Region: PRK05755
761193005500	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
761193005501	active site
761193005502	metal binding site 1 [ion binding]; metal-binding site
761193005503	putative 5' ssDNA interaction site; other site
761193005504	metal binding site 3; metal-binding site
761193005505	metal binding site 2 [ion binding]; metal-binding site
761193005506	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
761193005507	putative DNA binding site [nucleotide binding]; other site
761193005508	putative metal binding site [ion binding]; other site
761193005509	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
761193005510	active site
761193005511	catalytic site [active]
761193005512	substrate binding site [chemical binding]; other site
761193005513	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
761193005514	active site
761193005515	DNA binding site [nucleotide binding]
761193005516	catalytic site [active]
761193005517	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
761193005518	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
761193005519	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
761193005520	Protein export membrane protein; Region: SecD_SecF; pfam02355
761193005521	amino acid transporter; Region: 2A0306; TIGR00909
761193005522	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
761193005523	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193005524	Secretin and TonB N terminus short domain; Region: STN; pfam07660
761193005525	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193005526	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
761193005527	FecR protein; Region: FecR; pfam04773
761193005528	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
761193005529	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193005530	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193005531	DNA binding residues [nucleotide binding]
761193005532	Fatty acid desaturase; Region: FA_desaturase; pfam00487
761193005533	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
761193005534	putative di-iron ligands [ion binding]; other site
761193005535	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
761193005536	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
761193005537	CHAP domain; Region: CHAP; pfam05257
761193005538	TPR repeat; Region: TPR_11; pfam13414
761193005539	Tetratricopeptide repeat; Region: TPR_1; pfam00515
761193005540	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005541	binding surface
761193005542	TPR motif; other site
761193005543	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005544	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005545	TPR repeat; Region: TPR_11; pfam13414
761193005546	binding surface
761193005547	TPR motif; other site
761193005548	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005549	TPR motif; other site
761193005550	TPR repeat; Region: TPR_11; pfam13414
761193005551	binding surface
761193005552	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
761193005553	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
761193005554	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193005555	active site
761193005556	HIGH motif; other site
761193005557	nucleotide binding site [chemical binding]; other site
761193005558	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193005559	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193005560	active site
761193005561	KMSKS motif; other site
761193005562	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
761193005563	tRNA binding surface [nucleotide binding]; other site
761193005564	anticodon binding site; other site
761193005565	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193005566	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193005567	active site
761193005568	phosphorylation site [posttranslational modification]
761193005569	intermolecular recognition site; other site
761193005570	dimerization interface [polypeptide binding]; other site
761193005571	LytTr DNA-binding domain; Region: LytTR; smart00850
761193005572	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005573	binding surface
761193005574	TPR motif; other site
761193005575	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193005576	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193005577	binding surface
761193005578	TPR motif; other site
761193005579	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
761193005580	Histidine kinase; Region: HisKA_2; pfam07568
761193005581	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193005582	ATP binding site [chemical binding]; other site
761193005583	Mg2+ binding site [ion binding]; other site
761193005584	G-X-G motif; other site
761193005585	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193005586	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193005587	active site
761193005588	metal binding site [ion binding]; metal-binding site
761193005589	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005590	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
761193005591	active site
761193005592	8-oxo-dGMP binding site [chemical binding]; other site
761193005593	nudix motif; other site
761193005594	metal binding site [ion binding]; metal-binding site
761193005595	Domain of unknown function (DUF4301); Region: DUF4301; pfam14134
761193005596	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
761193005597	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005598	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
761193005599	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
761193005600	Walker A/P-loop; other site
761193005601	ATP binding site [chemical binding]; other site
761193005602	Q-loop/lid; other site
761193005603	ABC transporter signature motif; other site
761193005604	Walker B; other site
761193005605	D-loop; other site
761193005606	H-loop/switch region; other site
761193005607	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
761193005608	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
761193005609	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
761193005610	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
761193005611	dimerization interface [polypeptide binding]; other site
761193005612	active site
761193005613	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193005614	CotH protein; Region: CotH; pfam08757
761193005615	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
761193005616	putative metal binding residues [ion binding]; other site
761193005617	signature motif; other site
761193005618	dimer interface [polypeptide binding]; other site
761193005619	active site
761193005620	polyP binding site; other site
761193005621	substrate binding site [chemical binding]; other site
761193005622	acceptor-phosphate pocket; other site
761193005623	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
761193005624	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
761193005625	nucleotide binding site [chemical binding]; other site
761193005626	Type III pantothenate kinase; Region: Pan_kinase; cl17198
761193005627	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
761193005628	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
761193005629	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
761193005630	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
761193005631	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
761193005632	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
761193005633	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
761193005634	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
761193005635	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
761193005636	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
761193005637	Uncharacterized conserved protein [Function unknown]; Region: COG1739
761193005638	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
761193005639	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193005640	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193005641	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193005642	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193005643	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193005644	ligand binding site [chemical binding]; other site
761193005645	flexible hinge region; other site
761193005646	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
761193005647	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
761193005648	minor groove reading motif; other site
761193005649	helix-hairpin-helix signature motif; other site
761193005650	substrate binding pocket [chemical binding]; other site
761193005651	active site
761193005652	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193005653	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193005654	catalytic residue [active]
761193005655	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193005656	putative active site [active]
761193005657	Cupin superfamily (DUF985); Region: Cupin_5; pfam06172
761193005658	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
761193005659	active site
761193005660	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
761193005661	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
761193005662	homodimer interface [polypeptide binding]; other site
761193005663	substrate-cofactor binding pocket; other site
761193005664	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193005665	catalytic residue [active]
761193005666	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193005667	GLPGLI family protein; Region: GLPGLI; TIGR01200
761193005668	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193005669	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193005670	dimer interface [polypeptide binding]; other site
761193005671	phosphorylation site [posttranslational modification]
761193005672	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193005673	ATP binding site [chemical binding]; other site
761193005674	Mg2+ binding site [ion binding]; other site
761193005675	G-X-G motif; other site
761193005676	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193005677	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193005678	active site
761193005679	phosphorylation site [posttranslational modification]
761193005680	intermolecular recognition site; other site
761193005681	dimerization interface [polypeptide binding]; other site
761193005682	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193005683	DNA binding site [nucleotide binding]
761193005684	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193005685	Glycogen synthase; Region: Glycogen_syn; pfam05693
761193005686	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
761193005687	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
761193005688	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
761193005689	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
761193005690	O-succinylhomoserine sulfhydrylase; Validated; Region: PRK08133
761193005691	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
761193005692	homodimer interface [polypeptide binding]; other site
761193005693	substrate-cofactor binding pocket; other site
761193005694	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193005695	catalytic residue [active]
761193005696	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
761193005697	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
761193005698	Active Sites [active]
761193005699	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
761193005700	four helix bundle protein; Region: TIGR02436
761193005701	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
761193005702	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
761193005703	Active Sites [active]
761193005704	GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895
761193005705	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
761193005706	CysD dimerization site [polypeptide binding]; other site
761193005707	G1 box; other site
761193005708	putative GEF interaction site [polypeptide binding]; other site
761193005709	GTP/Mg2+ binding site [chemical binding]; other site
761193005710	Switch I region; other site
761193005711	G2 box; other site
761193005712	G3 box; other site
761193005713	Switch II region; other site
761193005714	G4 box; other site
761193005715	G5 box; other site
761193005716	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
761193005717	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
761193005718	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
761193005719	COGs: COG1373 ATPase (AAA+ superfamily); KEGG: dfe:Dfer_3330 AAA+ superfamily protein; SPTR: ATPase (AAA+ superfamily)-like protein
761193005720	AAA domain; Region: AAA_14; pfam13173
761193005721	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
761193005722	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
761193005723	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
761193005724	DNA-binding site [nucleotide binding]; DNA binding site
761193005725	Ligand-binding domain of a transcription repressor, FucR, which functions as a molecular sensor of L-fucose availability; Region: PBP1_FucR_like; cd06276
761193005726	putative ligand binding site [chemical binding]; other site
761193005727	putative dimerization interface [polypeptide binding]; other site
761193005728	Transcriptional regulators [Transcription]; Region: PurR; COG1609
761193005729	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193005730	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193005731	active site
761193005732	phosphorylation site [posttranslational modification]
761193005733	intermolecular recognition site; other site
761193005734	dimerization interface [polypeptide binding]; other site
761193005735	LytTr DNA-binding domain; Region: LytTR; smart00850
761193005736	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
761193005737	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
761193005738	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
761193005739	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193005740	Predicted permeases [General function prediction only]; Region: COG0795
761193005741	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
761193005742	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
761193005743	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
761193005744	Zn binding site [ion binding]; other site
761193005745	Phosphotransferase enzyme family; Region: APH; pfam01636
761193005746	Acyl-CoA dehydrogenase (ACAD) 10 and 11, N-terminal domain, and similar proteins. This subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs); Region: ACAD10_11_like; cd05154
761193005747	putative active site [active]
761193005748	putative substrate binding site [chemical binding]; other site
761193005749	ATP binding site [chemical binding]; other site
761193005750	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
761193005751	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
761193005752	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
761193005753	active site
761193005754	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193005755	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005756	Ion transport protein; Region: Ion_trans; pfam00520
761193005757	Ion channel; Region: Ion_trans_2; pfam07885
761193005758	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193005759	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
761193005760	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
761193005761	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
761193005762	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
761193005763	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193005764	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193005765	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193005766	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193005767	Protein of unknown function (DUF3089); Region: DUF3089; pfam11288
761193005768	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
761193005769	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
761193005770	Substrate binding site; other site
761193005771	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_6; cd06154
761193005772	homotrimer interaction site [polypeptide binding]; other site
761193005773	putative active site [active]
761193005774	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
761193005775	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
761193005776	GTP binding site; other site
761193005777	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429
761193005778	Class I aldolases; Region: Aldolase_Class_I; cl17187
761193005779	catalytic residue [active]
761193005780	Peptidase S8 family domain in Kp43 proteases; Region: Peptidases_S8_Kp43_protease; cd04842
761193005781	active site
761193005782	catalytic triad [active]
761193005783	RNA polymerase Rpb5, C-terminal domain; Region: RNA_pol_Rpb5_C; cl00883
761193005784	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005785	Peptidase S8 family domain in Kp43 proteases; Region: Peptidases_S8_Kp43_protease; cd04842
761193005786	active site
761193005787	catalytic triad [active]
761193005788	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005789	Malonate/sodium symporter MadM subunit; Region: MadM; cl04274
761193005790	Malonate transporter MadL subunit; Region: MadL; cl04273
761193005791	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
761193005792	Malonyl-CoA synthetase (MCS); Region: MCS; cd05941
761193005793	acyl-activating enzyme (AAE) consensus motif; other site
761193005794	active site
761193005795	AMP binding site [chemical binding]; other site
761193005796	CoA binding site [chemical binding]; other site
761193005797	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193005798	Walker A motif; other site
761193005799	ATP binding site [chemical binding]; other site
761193005800	Walker B motif; other site
761193005801	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
761193005802	Uncharacterized conserved protein [Function unknown]; Region: COG1284
761193005803	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
761193005804	COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005; KEGG: sli:Slin_2407 AraC family transcriptional regulator; PFAM: Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family
761193005805	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193005806	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193005807	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
761193005808	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Region: LPLAT_ABO13168-like; cd07988
761193005809	putative acyl-acceptor binding pocket; other site
761193005810	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
761193005811	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
761193005812	active site
761193005813	homodimer interface [polypeptide binding]; other site
761193005814	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
761193005815	ArsC family; Region: ArsC; pfam03960
761193005816	putative catalytic residues [active]
761193005817	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
761193005818	hydrophobic ligand binding site; other site
761193005819	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
761193005820	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
761193005821	Walker A/P-loop; other site
761193005822	ATP binding site [chemical binding]; other site
761193005823	Q-loop/lid; other site
761193005824	ABC transporter signature motif; other site
761193005825	Walker B; other site
761193005826	D-loop; other site
761193005827	H-loop/switch region; other site
761193005828	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
761193005829	geranylgeranylglyceryl phosphate synthase-like protein; Reviewed; Region: PRK04169
761193005830	PcrB family; Region: PcrB; pfam01884
761193005831	phosphate binding site [ion binding]; other site
761193005832	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
761193005833	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
761193005834	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193005835	active site
761193005836	HIGH motif; other site
761193005837	nucleotide binding site [chemical binding]; other site
761193005838	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
761193005839	KMSK motif region; other site
761193005840	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
761193005841	tRNA binding surface [nucleotide binding]; other site
761193005842	anticodon binding site; other site
761193005843	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193005844	Coenzyme A binding pocket [chemical binding]; other site
761193005845	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
761193005846	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
761193005847	HIGH motif; other site
761193005848	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
761193005849	active site
761193005850	KMSKS motif; other site
761193005851	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193005852	putative active site [active]
761193005853	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
761193005854	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
761193005855	active site
761193005856	dimer interface [polypeptide binding]; other site
761193005857	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
761193005858	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193005859	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193005860	salt bridge; other site
761193005861	non-specific DNA binding site [nucleotide binding]; other site
761193005862	sequence-specific DNA binding site [nucleotide binding]; other site
761193005863	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
761193005864	Ferritin-like domain; Region: Ferritin; pfam00210
761193005865	ferroxidase diiron center [ion binding]; other site
761193005866	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
761193005867	HNH endonuclease; Region: HNH_4; pfam13395
761193005868	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
761193005869	RNA 2'-phosphotransferase, Tpt1 / KptA family; Region: PTS_2-RNA; pfam01885
761193005870	Methyltransferase domain; Region: Methyltransf_23; pfam13489
761193005871	Methyltransferase domain; Region: Methyltransf_12; pfam08242
761193005872	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
761193005873	nucleotide binding site/active site [active]
761193005874	HIT family signature motif; other site
761193005875	catalytic residue [active]
761193005876	RNA ligase; Region: RNA_ligase; pfam09414
761193005877	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
761193005878	Zn2+ binding site [ion binding]; other site
761193005879	Mg2+ binding site [ion binding]; other site
761193005880	AAA domain; Region: AAA_33; pfam13671
761193005881	AAA domain; Region: AAA_17; pfam13207
761193005882	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
761193005883	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193005884	ATP binding site [chemical binding]; other site
761193005885	putative Mg++ binding site [ion binding]; other site
761193005886	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193005887	nucleotide binding region [chemical binding]; other site
761193005888	ATP-binding site [chemical binding]; other site
761193005889	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
761193005890	HRDC domain; Region: HRDC; pfam00570
761193005891	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
761193005892	putative DNA binding site [nucleotide binding]; other site
761193005893	putative Zn2+ binding site [ion binding]; other site
761193005894	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
761193005895	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193005896	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193005897	putative active site [active]
761193005898	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
761193005899	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
761193005900	trimer interface [polypeptide binding]; other site
761193005901	putative metal binding site [ion binding]; other site
761193005902	Histidine kinase; Region: His_kinase; pfam06580
761193005903	Response regulator receiver domain; Region: Response_reg; pfam00072
761193005904	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193005905	active site
761193005906	phosphorylation site [posttranslational modification]
761193005907	intermolecular recognition site; other site
761193005908	dimerization interface [polypeptide binding]; other site
761193005909	LytTr DNA-binding domain; Region: LytTR; smart00850
761193005910	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
761193005911	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
761193005912	NADP binding site [chemical binding]; other site
761193005913	active site
761193005914	putative substrate binding site [chemical binding]; other site
761193005915	LytB protein; Region: LYTB; cl00507
761193005916	(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); Region: ispH_lytB; TIGR00216
761193005917	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193005918	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193005919	active site
761193005920	metal binding site [ion binding]; metal-binding site
761193005921	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
761193005922	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
761193005923	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
761193005924	shikimate binding site; other site
761193005925	NAD(P) binding site [chemical binding]; other site
761193005926	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193005927	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005928	GTPase CgtA; Reviewed; Region: obgE; PRK12299
761193005929	GTP1/OBG; Region: GTP1_OBG; pfam01018
761193005930	Obg GTPase; Region: Obg; cd01898
761193005931	G1 box; other site
761193005932	GTP/Mg2+ binding site [chemical binding]; other site
761193005933	Switch I region; other site
761193005934	G2 box; other site
761193005935	G3 box; other site
761193005936	Switch II region; other site
761193005937	G4 box; other site
761193005938	G5 box; other site
761193005939	adenylate kinase; Reviewed; Region: adk; PRK00279
761193005940	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
761193005941	AMP-binding site [chemical binding]; other site
761193005942	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
761193005943	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193005944	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193005945	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193005946	dimer interface [polypeptide binding]; other site
761193005947	phosphorylation site [posttranslational modification]
761193005948	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193005949	ATP binding site [chemical binding]; other site
761193005950	Mg2+ binding site [ion binding]; other site
761193005951	G-X-G motif; other site
761193005952	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193005953	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193005954	active site
761193005955	phosphorylation site [posttranslational modification]
761193005956	intermolecular recognition site; other site
761193005957	dimerization interface [polypeptide binding]; other site
761193005958	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193005959	DNA binding site [nucleotide binding]
761193005960	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
761193005961	HEAT repeats; Region: HEAT_2; pfam13646
761193005962	HEAT repeats; Region: HEAT_2; pfam13646
761193005963	HEAT repeats; Region: HEAT_2; pfam13646
761193005964	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193005965	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193005966	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193005967	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193005968	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
761193005969	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
761193005970	active site
761193005971	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK01911
761193005972	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03708
761193005973	FOG: CBS domain [General function prediction only]; Region: COG0517
761193005974	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
761193005975	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
761193005976	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193005977	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193005978	ligand binding site [chemical binding]; other site
761193005979	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193005980	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
761193005981	active site
761193005982	DNA binding site [nucleotide binding]
761193005983	Int/Topo IB signature motif; other site
761193005984	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193005985	Domain of unknown function (DUF377); Region: DUF377; pfam04041
761193005986	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
761193005987	active site
761193005988	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
761193005989	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
761193005990	nucleotide binding site [chemical binding]; other site
761193005991	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
761193005992	classical (c) SDRs; Region: SDR_c; cd05233
761193005993	NAD(P) binding site [chemical binding]; other site
761193005994	active site
761193005995	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
761193005996	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
761193005997	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193005998	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
761193005999	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
761193006000	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193006001	metal binding site [ion binding]; metal-binding site
761193006002	NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.  Rhizobium and related species form nodules on the roots of their...; Region: NodN; cd03450
761193006003	putative active site [active]
761193006004	putative catalytic site [active]
761193006005	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
761193006006	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
761193006007	NAD(P) binding site [chemical binding]; other site
761193006008	homotetramer interface [polypeptide binding]; other site
761193006009	homodimer interface [polypeptide binding]; other site
761193006010	active site
761193006011	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
761193006012	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
761193006013	active site
761193006014	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193006015	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cl03075
761193006016	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
761193006017	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
761193006018	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
761193006019	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
761193006020	Uncharacterized protein conserved in bacteria (DUF2264); Region: DUF2264; pfam10022
761193006021	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
761193006022	Heme NO binding; Region: HNOB; pfam07700
761193006023	PAS domain S-box; Region: sensory_box; TIGR00229
761193006024	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193006025	putative active site [active]
761193006026	heme pocket [chemical binding]; other site
761193006027	PAS fold; Region: PAS_4; pfam08448
761193006028	PAS domain S-box; Region: sensory_box; TIGR00229
761193006029	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193006030	putative active site [active]
761193006031	heme pocket [chemical binding]; other site
761193006032	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193006033	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193006034	dimer interface [polypeptide binding]; other site
761193006035	phosphorylation site [posttranslational modification]
761193006036	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193006037	ATP binding site [chemical binding]; other site
761193006038	Mg2+ binding site [ion binding]; other site
761193006039	G-X-G motif; other site
761193006040	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193006041	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006042	active site
761193006043	phosphorylation site [posttranslational modification]
761193006044	intermolecular recognition site; other site
761193006045	dimerization interface [polypeptide binding]; other site
761193006046	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
761193006047	putative binding surface; other site
761193006048	active site
761193006049	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
761193006050	2-deoxy-D-gluconate 3-dehydrogenase; Region: kduD; TIGR01832
761193006051	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
761193006052	NADP binding site [chemical binding]; other site
761193006053	homodimer interface [polypeptide binding]; other site
761193006054	active site
761193006055	Transcriptional regulators [Transcription]; Region: PurR; COG1609
761193006056	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
761193006057	DNA binding site [nucleotide binding]
761193006058	domain linker motif; other site
761193006059	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
761193006060	ligand binding site [chemical binding]; other site
761193006061	dimerization interface [polypeptide binding]; other site
761193006062	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
761193006063	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
761193006064	active site
761193006065	metal binding site [ion binding]; metal-binding site
761193006066	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_3; cd09620
761193006067	putative ligand binding site [chemical binding]; other site
761193006068	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
761193006069	active site
761193006070	catalytic triad [active]
761193006071	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
761193006072	Endopygalactorunase [Cell envelope biogenesis, outer membrane]; Region: PGU1; COG5434
761193006073	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
761193006074	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193006075	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
761193006076	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193006077	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193006078	ligand binding site [chemical binding]; other site
761193006079	N-Terminal Domain Of Bc2l-C Lectin; Region: Bc2l-C_N; cd12211
761193006080	trimer interface [polypeptide binding]; other site
761193006081	ligand binding site [chemical binding]; other site
761193006082	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193006083	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
761193006084	Histidine kinase; Region: HisKA_2; pfam07568
761193006085	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193006086	ATP binding site [chemical binding]; other site
761193006087	Mg2+ binding site [ion binding]; other site
761193006088	G-X-G motif; other site
761193006089	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193006090	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006091	active site
761193006092	phosphorylation site [posttranslational modification]
761193006093	intermolecular recognition site; other site
761193006094	dimerization interface [polypeptide binding]; other site
761193006095	LytTr DNA-binding domain; Region: LytTR; smart00850
761193006096	acyl-CoA oxidase; Region: PLN02312
761193006097	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
761193006098	active site
761193006099	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
761193006100	active site
761193006101	catalytic triad [active]
761193006102	oxyanion hole [active]
761193006103	XisI protein; Region: XisI; pfam08869
761193006104	XisH protein; Region: XisH; pfam08814
761193006105	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006106	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193006107	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193006108	Haem-binding domain; Region: Haem_bd; pfam14376
761193006109	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
761193006110	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
761193006111	Uncharacterized conserved protein [Function unknown]; Region: COG3538
761193006112	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
761193006113	Alpha-L-fucosidase; Region: Alpha_L_fucos; pfam01120
761193006114	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
761193006115	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
761193006116	active site
761193006117	dimer interface [polypeptide binding]; other site
761193006118	catalytic nucleophile [active]
761193006119	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
761193006120	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
761193006121	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
761193006122	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
761193006123	active site
761193006124	zinc binding site [ion binding]; other site
761193006125	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_6; cd01844
761193006126	active site
761193006127	catalytic triad [active]
761193006128	oxyanion hole [active]
761193006129	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
761193006130	active site
761193006131	catalytic triad [active]
761193006132	oxyanion hole [active]
761193006133	Glyco_18 domain; Region: Glyco_18; smart00636
761193006134	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
761193006135	active site
761193006136	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
761193006137	B12 binding site [chemical binding]; other site
761193006138	Radical SAM superfamily; Region: Radical_SAM; pfam04055
761193006139	Predicted permeases [General function prediction only]; Region: COG0679
761193006140	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
761193006141	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
761193006142	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
761193006143	altronate oxidoreductase; Provisional; Region: PRK03643
761193006144	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
761193006145	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
761193006146	Glucuronate isomerase; Region: UxaC; pfam02614
761193006147	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
761193006148	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
761193006149	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
761193006150	substrate binding site [chemical binding]; other site
761193006151	ATP binding site [chemical binding]; other site
761193006152	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
761193006153	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
761193006154	active site
761193006155	intersubunit interface [polypeptide binding]; other site
761193006156	catalytic residue [active]
761193006157	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193006158	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193006159	putative substrate translocation pore; other site
761193006160	Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893
761193006161	SnoaL-like domain; Region: SnoaL_3; pfam13474
761193006162	Phosphoglycerate kinase; Region: PGK; pfam00162
761193006163	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
761193006164	substrate binding site [chemical binding]; other site
761193006165	hinge regions; other site
761193006166	ADP binding site [chemical binding]; other site
761193006167	catalytic site [active]
761193006168	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
761193006169	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
761193006170	K+ potassium transporter; Region: K_trans; pfam02705
761193006171	K+ potassium transporter; Region: K_trans; pfam02705
761193006172	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193006173	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193006174	NAD(P) binding site [chemical binding]; other site
761193006175	active site
761193006176	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
761193006177	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
761193006178	30S subunit binding site; other site
761193006179	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193006180	Amidohydrolase; Region: Amidohydro_4; pfam13147
761193006181	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193006182	active site
761193006183	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
761193006184	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
761193006185	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
761193006186	dimer interface [polypeptide binding]; other site
761193006187	motif 1; other site
761193006188	active site
761193006189	motif 2; other site
761193006190	motif 3; other site
761193006191	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
761193006192	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
761193006193	2-phosphosulpholactate phosphatase; Region: 2-ph_phosp; pfam04029
761193006194	Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only]; Region: COG2045
761193006195	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
761193006196	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
761193006197	substrate binding site [chemical binding]; other site
761193006198	glutamase interaction surface [polypeptide binding]; other site
761193006199	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193006200	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006201	active site
761193006202	phosphorylation site [posttranslational modification]
761193006203	intermolecular recognition site; other site
761193006204	dimerization interface [polypeptide binding]; other site
761193006205	LytTr DNA-binding domain; Region: LytTR; smart00850
761193006206	Histidine kinase; Region: His_kinase; pfam06580
761193006207	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
761193006208	ATP binding site [chemical binding]; other site
761193006209	Mg2+ binding site [ion binding]; other site
761193006210	G-X-G motif; other site
761193006211	Uncharacterized conserved protein [Function unknown]; Region: COG2353
761193006212	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
761193006213	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193006214	putative active site [active]
761193006215	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193006216	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006217	active site
761193006218	phosphorylation site [posttranslational modification]
761193006219	intermolecular recognition site; other site
761193006220	dimerization interface [polypeptide binding]; other site
761193006221	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193006222	DNA binding site [nucleotide binding]
761193006223	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
761193006224	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
761193006225	active site
761193006226	Zn binding site [ion binding]; other site
761193006227	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193006228	S-adenosylmethionine binding site [chemical binding]; other site
761193006229	RNA polymerase sigma factor SigW; Provisional; Region: PRK09641
761193006230	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193006231	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193006232	DNA binding residues [nucleotide binding]
761193006233	Domain of unknown function (DUF3416); Region: DUF3416; pfam11896
761193006234	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
761193006235	Alpha amylase catalytic domain found in GlgE-like proteins; Region: AmyAc_GlgE_like; cd11344
761193006236	active site
761193006237	homodimer interface [polypeptide binding]; other site
761193006238	catalytic site [active]
761193006239	acceptor binding site [chemical binding]; other site
761193006240	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193006241	non-specific DNA binding site [nucleotide binding]; other site
761193006242	salt bridge; other site
761193006243	sequence-specific DNA binding site [nucleotide binding]; other site
761193006244	NADH dehydrogenase subunit 2; Validated; Region: ND2; MTH00011
761193006245	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
761193006246	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
761193006247	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
761193006248	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
761193006249	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
761193006250	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
761193006251	NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus; Region: Oxidored_q1_C; pfam01010
761193006252	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
761193006253	integral membrane protein MviN; Region: mviN; TIGR01695
761193006254	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
761193006255	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
761193006256	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193006257	active site
761193006258	motif I; other site
761193006259	motif II; other site
761193006260	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
761193006261	ligand binding site; other site
761193006262	tetramer interface; other site
761193006263	NeuB family; Region: NeuB; pfam03102
761193006264	ferrochelatase; Reviewed; Region: hemH; PRK00035
761193006265	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
761193006266	C-terminal domain interface [polypeptide binding]; other site
761193006267	active site
761193006268	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
761193006269	active site
761193006270	N-terminal domain interface [polypeptide binding]; other site
761193006271	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
761193006272	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
761193006273	GatB domain; Region: GatB_Yqey; smart00845
761193006274	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
761193006275	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
761193006276	active site
761193006277	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006278	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193006279	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
761193006280	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
761193006281	active site
761193006282	substrate binding site [chemical binding]; other site
761193006283	cosubstrate binding site; other site
761193006284	catalytic site [active]
761193006285	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193006286	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
761193006287	LysE type translocator; Region: LysE; cl00565
761193006288	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
761193006289	ADP-ribose binding site [chemical binding]; other site
761193006290	dimer interface [polypeptide binding]; other site
761193006291	active site
761193006292	nudix motif; other site
761193006293	metal binding site [ion binding]; metal-binding site
761193006294	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
761193006295	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
761193006296	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
761193006297	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
761193006298	active site
761193006299	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193006300	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193006301	Histidine kinase; Region: His_kinase; pfam06580
761193006302	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006303	Response regulator receiver domain; Region: Response_reg; pfam00072
761193006304	active site
761193006305	phosphorylation site [posttranslational modification]
761193006306	intermolecular recognition site; other site
761193006307	dimerization interface [polypeptide binding]; other site
761193006308	LytTr DNA-binding domain; Region: LytTR; smart00850
761193006309	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193006310	FtsX-like permease family; Region: FtsX; pfam02687
761193006311	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
761193006312	FtsX-like permease family; Region: FtsX; pfam02687
761193006313	Predicted transcriptional regulators [Transcription]; Region: COG1695
761193006314	Transcriptional regulator PadR-like family; Region: PadR; cl17335
761193006315	metabolite-proton symporter; Region: 2A0106; TIGR00883
761193006316	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193006317	putative substrate translocation pore; other site
761193006318	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193006319	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
761193006320	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193006321	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193006322	DNA binding residues [nucleotide binding]
761193006323	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
761193006324	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
761193006325	oligomer interface [polypeptide binding]; other site
761193006326	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
761193006327	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
761193006328	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
761193006329	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
761193006330	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
761193006331	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
761193006332	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
761193006333	Surface antigen; Region: Bac_surface_Ag; pfam01103
761193006334	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
761193006335	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
761193006336	catalytic residue [active]
761193006337	putative FPP diphosphate  binding site; other site
761193006338	putative FPP binding hydrophobic cleft; other site
761193006339	dimer interface [polypeptide binding]; other site
761193006340	putative IPP diphosphate binding site; other site
761193006341	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_14; cd13139
761193006342	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
761193006343	FOG: WD40 repeat [General function prediction only]; Region: COG2319
761193006344	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
761193006345	structural tetrad; other site
761193006346	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
761193006347	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
761193006348	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
761193006349	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
761193006350	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
761193006351	NAD binding site [chemical binding]; other site
761193006352	homodimer interface [polypeptide binding]; other site
761193006353	active site
761193006354	substrate binding site [chemical binding]; other site
761193006355	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
761193006356	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
761193006357	NAD binding site [chemical binding]; other site
761193006358	substrate binding site [chemical binding]; other site
761193006359	homodimer interface [polypeptide binding]; other site
761193006360	active site
761193006361	Cna protein B-type domain; Region: Cna_B; pfam05738
761193006362	conserved repeat domain; Region: B_ant_repeat; TIGR01451
761193006363	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
761193006364	putative acyl-acceptor binding pocket; other site
761193006365	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193006366	LytTr DNA-binding domain; Region: LytTR; smart00850
761193006367	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193006368	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
761193006369	active site
761193006370	phosphorylation site [posttranslational modification]
761193006371	intermolecular recognition site; other site
761193006372	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
761193006373	DNA binding residues [nucleotide binding]
761193006374	dimerization interface [polypeptide binding]; other site
761193006375	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
761193006376	active site
761193006377	multimer interface [polypeptide binding]; other site
761193006378	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
761193006379	DHH family; Region: DHH; pfam01368
761193006380	DHHA1 domain; Region: DHHA1; pfam02272
761193006381	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
761193006382	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
761193006383	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
761193006384	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
761193006385	active site
761193006386	dimerization interface [polypeptide binding]; other site
761193006387	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
761193006388	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
761193006389	DivIVA protein; Region: DivIVA; pfam05103
761193006390	DivIVA domain; Region: DivI1A_domain; TIGR03544
761193006391	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
761193006392	Dihydroneopterin aldolase [Coenzyme metabolism]; Region: FolB; COG1539
761193006393	active site
761193006394	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193006395	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193006396	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
761193006397	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
761193006398	Surface antigen; Region: Bac_surface_Ag; pfam01103
761193006399	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
761193006400	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193006401	acetylornithine aminotransferase; Provisional; Region: PRK02627
761193006402	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
761193006403	inhibitor-cofactor binding pocket; inhibition site
761193006404	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193006405	catalytic residue [active]
761193006406	Uncharacterized conserved protein [Function unknown]; Region: COG3379
761193006407	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
761193006408	Dehydroquinate synthase (DHQS)-like. DHQS catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS-like2; cd08198
761193006409	active site
761193006410	metal binding site [ion binding]; metal-binding site
761193006411	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
761193006412	UbiA prenyltransferase family; Region: UbiA; pfam01040
761193006413	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
761193006414	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193006415	active site
761193006416	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
761193006417	trimer interface [polypeptide binding]; other site
761193006418	dimer interface [polypeptide binding]; other site
761193006419	putative active site [active]
761193006420	HEAT repeats; Region: HEAT_2; pfam13646
761193006421	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193006422	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193006423	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193006424	DNA binding residues [nucleotide binding]
761193006425	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
761193006426	N-acetylornithine carbamoyltransferase; Reviewed; Region: PRK04523
761193006427	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
761193006428	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
761193006429	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
761193006430	catalytic residues [active]
761193006431	dimer interface [polypeptide binding]; other site
761193006432	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
761193006433	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
761193006434	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
761193006435	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
761193006436	hydroxyglutarate oxidase; Provisional; Region: PRK11728
761193006437	Predicted dehydrogenase [General function prediction only]; Region: COG0579
761193006438	putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ; Provisional; Region: PRK09677
761193006439	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
761193006440	trimer interface [polypeptide binding]; other site
761193006441	active site
761193006442	substrate binding site [chemical binding]; other site
761193006443	CoA binding site [chemical binding]; other site
761193006444	COGs: COG1668 ABC-type Na+ efflux pump permease component; InterPro IPR013525; KEGG: sli:Slin_1740 ABC-type Na+ efflux pump permease-like protein; PFAM: ABC-2 type transporter; SPTR: ABC-type Na+ efflux pump permease component-like protein
761193006445	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
761193006446	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
761193006447	ATP-binding cassette domain of an uncharacterized transporter; Region: ABC_putative_ATPase; cd03269
761193006448	Walker A/P-loop; other site
761193006449	ATP binding site [chemical binding]; other site
761193006450	Q-loop/lid; other site
761193006451	ABC transporter signature motif; other site
761193006452	Walker B; other site
761193006453	D-loop; other site
761193006454	H-loop/switch region; other site
761193006455	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
761193006456	Cytochrome c; Region: Cytochrom_C; pfam00034
761193006457	SdiA-regulated; Region: SdiA-regulated; cd09971
761193006458	putative active site [active]
761193006459	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
761193006460	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193006461	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193006462	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193006463	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
761193006464	Uncharacterized aldehyde dehydrogenase of Synechococcus sp. PCC 7335 (EDX86601); Region: ALDH_EDX86601; cd07102
761193006465	NAD(P) binding site [chemical binding]; other site
761193006466	catalytic residues [active]
761193006467	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
761193006468	catalytic triad [active]
761193006469	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193006470	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193006471	GLPGLI family protein; Region: GLPGLI; TIGR01200
761193006472	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193006473	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193006474	KEGG: lby:Lbys_2405 transposase IS3/is911 family protein; SPTR: Transposase IS3/IS911 family protein
761193006475	Prodigal; manually curated
761193006476	KEGG: aas:Aasi_1293 hypothetical protein; SPTR:  uncharacterized protein
761193006477	30S ribosomal protein S7; Validated; Region: PRK05302
761193006478	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
761193006479	S17 interaction site [polypeptide binding]; other site
761193006480	S8 interaction site; other site
761193006481	16S rRNA interaction site [nucleotide binding]; other site
761193006482	streptomycin interaction site [chemical binding]; other site
761193006483	23S rRNA interaction site [nucleotide binding]; other site
761193006484	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
761193006485	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193006486	active site residue [active]
761193006487	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
761193006488	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193006489	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006490	active site
761193006491	phosphorylation site [posttranslational modification]
761193006492	intermolecular recognition site; other site
761193006493	dimerization interface [polypeptide binding]; other site
761193006494	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
761193006495	DNA binding residues [nucleotide binding]
761193006496	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
761193006497	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193006498	Histidine kinase; Region: HisKA_3; pfam07730
761193006499	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193006500	ATP binding site [chemical binding]; other site
761193006501	Mg2+ binding site [ion binding]; other site
761193006502	G-X-G motif; other site
761193006503	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
761193006504	nitrite reductase subunit NirD; Provisional; Region: PRK14989
761193006505	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193006506	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
761193006507	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
761193006508	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
761193006509	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
761193006510	active site
761193006511	SAM binding site [chemical binding]; other site
761193006512	homodimer interface [polypeptide binding]; other site
761193006513	Acetyl esterase (deacetylase) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3458
761193006514	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
761193006515	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
761193006516	homodimer interface [polypeptide binding]; other site
761193006517	substrate-cofactor binding pocket; other site
761193006518	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193006519	catalytic residue [active]
761193006520	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
761193006521	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
761193006522	dimerization interface [polypeptide binding]; other site
761193006523	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193006524	dimer interface [polypeptide binding]; other site
761193006525	phosphorylation site [posttranslational modification]
761193006526	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193006527	ATP binding site [chemical binding]; other site
761193006528	Mg2+ binding site [ion binding]; other site
761193006529	G-X-G motif; other site
761193006530	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193006531	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006532	active site
761193006533	phosphorylation site [posttranslational modification]
761193006534	intermolecular recognition site; other site
761193006535	dimerization interface [polypeptide binding]; other site
761193006536	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193006537	DNA binding site [nucleotide binding]
761193006538	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193006539	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193006540	Cytochrome c; Region: Cytochrom_C; cl11414
761193006541	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
761193006542	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193006543	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
761193006544	nudix motif; other site
761193006545	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
761193006546	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193006547	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006548	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193006549	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193006550	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193006551	SusD family; Region: SusD; pfam07980
761193006552	Family description; Region: VCBS; pfam13517
761193006553	Family description; Region: VCBS; pfam13517
761193006554	Family description; Region: VCBS; pfam13517
761193006555	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
761193006556	Family description; Region: VCBS; pfam13517
761193006557	Family description; Region: VCBS; pfam13517
761193006558	Family description; Region: VCBS; pfam13517
761193006559	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
761193006560	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39B; cd02418
761193006561	putative active site [active]
761193006562	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193006563	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193006564	Walker A/P-loop; other site
761193006565	ATP binding site [chemical binding]; other site
761193006566	Q-loop/lid; other site
761193006567	ABC transporter signature motif; other site
761193006568	Walker B; other site
761193006569	D-loop; other site
761193006570	H-loop/switch region; other site
761193006571	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
761193006572	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193006573	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193006574	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006575	Predicted membrane protein [Function unknown]; Region: COG3671
761193006576	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193006577	non-specific DNA binding site [nucleotide binding]; other site
761193006578	salt bridge; other site
761193006579	sequence-specific DNA binding site [nucleotide binding]; other site
761193006580	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006581	Response regulator receiver domain; Region: Response_reg; pfam00072
761193006582	active site
761193006583	phosphorylation site [posttranslational modification]
761193006584	intermolecular recognition site; other site
761193006585	dimerization interface [polypeptide binding]; other site
761193006586	LytTr DNA-binding domain; Region: LytTR; smart00850
761193006587	Histidine kinase; Region: His_kinase; pfam06580
761193006588	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006589	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193006590	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193006591	LanC-like proteins. LanC is the cyclase enzyme of the lanthionine synthetase. Lanthionine is a lantibiotic, a unique class of peptide antibiotics. They are ribosomally synthesized as a precursor peptide and then post-translationally modified to contain...; Region: LanC_like; cl04955
761193006592	Lanthionine synthetase C-like protein; Region: LANC_like; pfam05147
761193006593	active site
761193006594	zinc binding site [ion binding]; other site
761193006595	Lantibiotic dehydratase, N terminus; Region: Lant_dehyd_N; pfam04737
761193006596	Lantibiotic dehydratase, C terminus; Region: Lant_dehyd_C; pfam04738
761193006597	thiopeptide-type bacteriocin biosynthesis domain; Region: thiopep_ocin; TIGR03891
761193006598	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
761193006599	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
761193006600	putative active site [active]
761193006601	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193006602	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
761193006603	Walker A/P-loop; other site
761193006604	ATP binding site [chemical binding]; other site
761193006605	Q-loop/lid; other site
761193006606	ABC transporter signature motif; other site
761193006607	Walker B; other site
761193006608	D-loop; other site
761193006609	H-loop/switch region; other site
761193006610	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193006611	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193006612	catalytic residues [active]
761193006613	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193006614	non-specific DNA binding site [nucleotide binding]; other site
761193006615	salt bridge; other site
761193006616	sequence-specific DNA binding site [nucleotide binding]; other site
761193006617	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193006618	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193006619	SusD family; Region: SusD; pfam07980
761193006620	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193006621	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006622	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193006623	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193006624	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193006625	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006626	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193006627	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
761193006628	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193006629	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193006630	SusD family; Region: SusD; pfam07980
761193006631	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
761193006632	active site lid residues [active]
761193006633	substrate binding pocket [chemical binding]; other site
761193006634	catalytic residues [active]
761193006635	substrate-Mg2+ binding site; other site
761193006636	aspartate-rich region 1; other site
761193006637	aspartate-rich region 2; other site
761193006638	phytoene desaturase; Region: crtI_fam; TIGR02734
761193006639	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193006640	RAB proteins geranylgeranyltransferase component A (RAB escort protein) [Posttranslational modification, protein turnover, chaperones]; Region: MRS6; cl17678
761193006641	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193006642	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193006643	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193006644	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006645	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193006646	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193006647	Predicted acyl esterases [General function prediction only]; Region: COG2936
761193006648	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
761193006649	FlgD Ig-like domain; Region: FlgD_ig; pfam13860
761193006650	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
761193006651	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
761193006652	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
761193006653	Uncharacterized conserved protein [Function unknown]; Region: COG1912
761193006654	Protein of unknown function (DUF1343); Region: DUF1343; cl01598
761193006655	high affinity sulphate transporter 1; Region: sulP; TIGR00815
761193006656	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
761193006657	Sulfate transporter family; Region: Sulfate_transp; pfam00916
761193006658	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
761193006659	Fatty acid desaturase; Region: FA_desaturase_2; pfam03405
761193006660	Acyl ACP desaturase, ferritin-like diiron-binding domain; Region: Acyl_ACP_Desat; cd01050
761193006661	homodimer interface [polypeptide binding]; other site
761193006662	putative substrate binding pocket [chemical binding]; other site
761193006663	diiron center [ion binding]; other site
761193006664	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
761193006665	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
761193006666	putative acyl-acceptor binding pocket; other site
761193006667	high affinity sulphate transporter 1; Region: sulP; TIGR00815
761193006668	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
761193006669	Sulfate transporter family; Region: Sulfate_transp; pfam00916
761193006670	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
761193006671	Sulfate transporter family; Region: Sulfate_transp; pfam00916
761193006672	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
761193006673	active site clefts [active]
761193006674	zinc binding site [ion binding]; other site
761193006675	dimer interface [polypeptide binding]; other site
761193006676	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
761193006677	putative ligand binding site [chemical binding]; other site
761193006678	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193006679	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193006680	catalytic residues [active]
761193006681	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
761193006682	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193006683	putative substrate translocation pore; other site
761193006684	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193006685	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193006686	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
761193006687	rhamnose-proton symporter; Provisional; Region: PRK13499
761193006688	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
761193006689	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13539
761193006690	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193006691	Walker A/P-loop; other site
761193006692	ATP binding site [chemical binding]; other site
761193006693	Q-loop/lid; other site
761193006694	ABC transporter signature motif; other site
761193006695	Walker B; other site
761193006696	D-loop; other site
761193006697	H-loop/switch region; other site
761193006698	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193006699	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
761193006700	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193006701	DNA interaction; other site
761193006702	Metal-binding active site; metal-binding site
761193006703	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
761193006704	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
761193006705	generic binding surface II; other site
761193006706	ssDNA binding site; other site
761193006707	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193006708	ATP binding site [chemical binding]; other site
761193006709	putative Mg++ binding site [ion binding]; other site
761193006710	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193006711	nucleotide binding region [chemical binding]; other site
761193006712	ATP-binding site [chemical binding]; other site
761193006713	Transposase IS200 like; Region: Y1_Tnp; cl00848
761193006714	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
761193006715	Part of AAA domain; Region: AAA_19; pfam13245
761193006716	Family description; Region: UvrD_C_2; pfam13538
761193006717	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193006718	putative active site [active]
761193006719	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
761193006720	RuvA N terminal domain; Region: RuvA_N; pfam01330
761193006721	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
761193006722	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
761193006723	Predicted membrane protein (DUF2306); Region: DUF2306; cl02232
761193006724	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
761193006725	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
761193006726	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193006727	catalytic residue [active]
761193006728	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
761193006729	active site
761193006730	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
761193006731	active site
761193006732	ribulose/triose binding site [chemical binding]; other site
761193006733	phosphate binding site [ion binding]; other site
761193006734	substrate (anthranilate) binding pocket [chemical binding]; other site
761193006735	product (indole) binding pocket [chemical binding]; other site
761193006736	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193006737	putative active site [active]
761193006738	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
761193006739	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
761193006740	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
761193006741	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
761193006742	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
761193006743	domain interfaces; other site
761193006744	active site
761193006745	XisI protein; Region: XisI; pfam08869
761193006746	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
761193006747	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
761193006748	putative ribose interaction site [chemical binding]; other site
761193006749	putative ADP binding site [chemical binding]; other site
761193006750	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
761193006751	Glutamine amidotransferase class-I; Region: GATase; pfam00117
761193006752	glutamine binding [chemical binding]; other site
761193006753	catalytic triad [active]
761193006754	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
761193006755	active site
761193006756	dimer interfaces [polypeptide binding]; other site
761193006757	catalytic residues [active]
761193006758	NAD+ synthase (glutamine-hydrolysing); Region: PLN02339
761193006759	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
761193006760	multimer interface [polypeptide binding]; other site
761193006761	active site
761193006762	catalytic triad [active]
761193006763	protein interface 1 [polypeptide binding]; other site
761193006764	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
761193006765	homodimer interface [polypeptide binding]; other site
761193006766	NAD binding pocket [chemical binding]; other site
761193006767	ATP binding pocket [chemical binding]; other site
761193006768	Mg binding site [ion binding]; other site
761193006769	active-site loop [active]
761193006770	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
761193006771	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193006772	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
761193006773	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193006774	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006775	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
761193006776	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193006777	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193006778	Calx-beta domain; Region: Calx-beta; cl02522
761193006779	Zinc-dependent metalloprotease, pappalysin_like subfamily. The pregnancy-associated plasma protein A (PAPP-A or pappalysin-1) cleaves insulin-like growth factor-binding proteins 4 and 5, thereby promoting cell growth by releasing bound growth factor; Region: ZnMc_pappalysin_like; cd04275
761193006780	active site
761193006781	FOG: PKD repeat [General function prediction only]; Region: COG3291
761193006782	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193006783	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193006784	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
761193006785	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
761193006786	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
761193006787	HEPN domain; Region: HEPN; cl00824
761193006788	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
761193006789	active site
761193006790	SAM binding site [chemical binding]; other site
761193006791	homodimer interface [polypeptide binding]; other site
761193006792	hypothetical protein; Validated; Region: PRK07411
761193006793	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
761193006794	ATP binding site [chemical binding]; other site
761193006795	substrate interface [chemical binding]; other site
761193006796	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193006797	active site residue [active]
761193006798	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
761193006799	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
761193006800	classical (c) SDRs; Region: SDR_c; cd05233
761193006801	NAD(P) binding site [chemical binding]; other site
761193006802	active site
761193006803	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
761193006804	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
761193006805	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
761193006806	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
761193006807	iron-sulfur cluster [ion binding]; other site
761193006808	[2Fe-2S] cluster binding site [ion binding]; other site
761193006809	Prodigal; manually curated
761193006810	Prodigal; manually curated
761193006811	KEGG: sli:Slin_3616 hypothetical protein; SPTR:  uncharacterized protein
761193006812	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
761193006813	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
761193006814	active site
761193006815	SprT-like family; Region: SprT-like; pfam10263
761193006816	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
761193006817	Clp protease; Region: CLP_protease; pfam00574
761193006818	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
761193006819	oligomer interface [polypeptide binding]; other site
761193006820	active site residues [active]
761193006821	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
761193006822	Domain of unknown function (DUF814); Region: DUF814; pfam05670
761193006823	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
761193006824	Transcriptional regulators [Transcription]; Region: PurR; COG1609
761193006825	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
761193006826	DNA binding site [nucleotide binding]
761193006827	domain linker motif; other site
761193006828	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
761193006829	dimerization interface [polypeptide binding]; other site
761193006830	ligand binding site [chemical binding]; other site
761193006831	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193006832	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193006833	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193006834	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193006835	Methane oxygenase PmoA; Region: PmoA; pfam14100
761193006836	mannonate dehydratase; Provisional; Region: PRK03906
761193006837	mannonate dehydratase; Region: uxuA; TIGR00695
761193006838	Transposase IS200 like; Region: Y1_Tnp; pfam01797
761193006839	Alpha-glucuronidase [Carbohydrate transport and metabolism]; Region: AguA; COG3661
761193006840	Glycosyl hydrolase family 67 N-terminus; Region: Glyco_hydro_67N; pfam03648
761193006841	Glycosyl hydrolase family 67 C-terminus; Region: Glyco_hydro_67C; pfam07477
761193006842	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
761193006843	classical (c) SDRs; Region: SDR_c; cd05233
761193006844	NAD(P) binding site [chemical binding]; other site
761193006845	active site
761193006846	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193006847	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193006848	catalytic residues [active]
761193006849	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193006850	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193006851	Cupin domain; Region: Cupin_2; pfam07883
761193006852	Cupin domain; Region: Cupin_2; pfam07883
761193006853	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
761193006854	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
761193006855	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
761193006856	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cd00413
761193006857	active site
761193006858	catalytic residues [active]
761193006859	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193006860	Sulfatase; Region: Sulfatase; cl17466
761193006861	similar to Arylsulfatase; PFAM: Bacterial alpha-L-rhamnosidase; Sulfatase; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006225:IPR002942:IPR006145; KEGG: sli:Slin_2869 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RluC/RluD
761193006862	similar to RluA family pseudouridine synthase; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family
761193006863	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
761193006864	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
761193006865	Proline racemase [Amino acid transport and metabolism]; Region: COG3938
761193006866	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
761193006867	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
761193006868	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
761193006869	molybdopterin cofactor binding site; other site
761193006870	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
761193006871	molybdopterin cofactor binding site; other site
761193006872	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
761193006873	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193006874	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
761193006875	nitrite extrusion protein (nitrite facilitator); Region: 2A0108; TIGR00886
761193006876	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193006877	putative substrate translocation pore; other site
761193006878	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
761193006879	Anthranilate phosphoribosyltransferase [Amino acid transport and metabolism]; Region: TrpD; COG0547
761193006880	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
761193006881	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
761193006882	Ligand Binding Site [chemical binding]; other site
761193006883	Protein of unknown function (DUF3316); Region: DUF3316; pfam11777
761193006884	Histidine kinase; Region: His_kinase; pfam06580
761193006885	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193006886	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006887	active site
761193006888	phosphorylation site [posttranslational modification]
761193006889	intermolecular recognition site; other site
761193006890	dimerization interface [polypeptide binding]; other site
761193006891	LytTr DNA-binding domain; Region: LytTR; smart00850
761193006892	Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377
761193006893	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
761193006894	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
761193006895	active site
761193006896	intersubunit interface [polypeptide binding]; other site
761193006897	zinc binding site [ion binding]; other site
761193006898	Na+ binding site [ion binding]; other site
761193006899	hypothetical protein; Provisional; Region: PRK08201
761193006900	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
761193006901	metal binding site [ion binding]; metal-binding site
761193006902	putative dimer interface [polypeptide binding]; other site
761193006903	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193006904	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: GT1_like_1; cd04950
761193006905	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193006906	putative homodimer interface [polypeptide binding]; other site
761193006907	Response regulator receiver domain; Region: Response_reg; pfam00072
761193006908	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193006909	active site
761193006910	phosphorylation site [posttranslational modification]
761193006911	intermolecular recognition site; other site
761193006912	dimerization interface [polypeptide binding]; other site
761193006913	CheB methylesterase; Region: CheB_methylest; pfam01339
761193006914	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
761193006915	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
761193006916	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
761193006917	PAS domain; Region: PAS_9; pfam13426
761193006918	PAS domain S-box; Region: sensory_box; TIGR00229
761193006919	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193006920	putative active site [active]
761193006921	heme pocket [chemical binding]; other site
761193006922	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193006923	dimer interface [polypeptide binding]; other site
761193006924	phosphorylation site [posttranslational modification]
761193006925	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193006926	ATP binding site [chemical binding]; other site
761193006927	Mg2+ binding site [ion binding]; other site
761193006928	G-X-G motif; other site
761193006929	CheB methylesterase; Region: CheB_methylest; pfam01339
761193006930	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
761193006931	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193006932	NAD(P) binding site [chemical binding]; other site
761193006933	active site
761193006934	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
761193006935	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
761193006936	NAD binding site [chemical binding]; other site
761193006937	catalytic Zn binding site [ion binding]; other site
761193006938	structural Zn binding site [ion binding]; other site
761193006939	Fatty acid desaturase; Region: FA_desaturase; pfam00487
761193006940	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
761193006941	putative di-iron ligands [ion binding]; other site
761193006942	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
761193006943	Protein of unknown function (DUF779); Region: DUF779; pfam05610
761193006944	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
761193006945	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
761193006946	NAD(P) binding site [chemical binding]; other site
761193006947	catalytic residues [active]
761193006948	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193006949	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193006950	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
761193006951	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
761193006952	active site
761193006953	trimer interface [polypeptide binding]; other site
761193006954	allosteric site; other site
761193006955	active site lid [active]
761193006956	hexamer (dimer of trimers) interface [polypeptide binding]; other site
761193006957	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193006958	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193006959	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
761193006960	MutS domain I; Region: MutS_I; pfam01624
761193006961	MutS domain II; Region: MutS_II; pfam05188
761193006962	MutS domain III; Region: MutS_III; pfam05192
761193006963	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
761193006964	Walker A/P-loop; other site
761193006965	ATP binding site [chemical binding]; other site
761193006966	Q-loop/lid; other site
761193006967	ABC transporter signature motif; other site
761193006968	Walker B; other site
761193006969	D-loop; other site
761193006970	H-loop/switch region; other site
761193006971	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
761193006972	Leucine-rich repeats; other site
761193006973	Substrate binding site [chemical binding]; other site
761193006974	Leucine rich repeat; Region: LRR_8; pfam13855
761193006975	Leucine rich repeat; Region: LRR_8; pfam13855
761193006976	Leucine rich repeat; Region: LRR_8; pfam13855
761193006977	Leucine rich repeat; Region: LRR_8; pfam13855
761193006978	InterPro IPR011701; KEGG: sli:Slin_0372 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1
761193006979	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193006980	H+ Antiporter protein; Region: 2A0121; TIGR00900
761193006981	putative substrate translocation pore; other site
761193006982	Cupin domain; Region: Cupin_2; pfam07883
761193006983	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193006984	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193006985	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193006986	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193006987	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193006988	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
761193006989	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193006990	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193006991	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
761193006992	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
761193006993	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193006994	Sulfatase; Region: Sulfatase; pfam00884
761193006995	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
761193006996	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
761193006997	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193006998	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
761193006999	metal binding site [ion binding]; metal-binding site
761193007000	substrate binding pocket [chemical binding]; other site
761193007001	short chain dehydrogenase; Provisional; Region: PRK06138
761193007002	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193007003	NAD(P) binding site [chemical binding]; other site
761193007004	active site
761193007005	Domain of unknown function (DUF718); Region: DUF718; cl01281
761193007006	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
761193007007	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193007008	putative substrate translocation pore; other site
761193007009	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193007010	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
761193007011	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
761193007012	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
761193007013	sugar binding site [chemical binding]; other site
761193007014	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
761193007015	Glycosyl hydrolase 43-like family consists of hypothetical proteins; Region: GH43_like_2; cd08994
761193007016	active site
761193007017	Glycosyl hydrolase 43-like family consists of hypothetical proteins; Region: GH43_like_2; cd08994
761193007018	active site
761193007019	Transcriptional regulators [Transcription]; Region: PurR; COG1609
761193007020	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
761193007021	DNA binding site [nucleotide binding]
761193007022	domain linker motif; other site
761193007023	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
761193007024	dimerization interface [polypeptide binding]; other site
761193007025	ligand binding site [chemical binding]; other site
761193007026	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193007027	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193007028	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193007029	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193007030	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193007031	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
761193007032	putative metal binding site [ion binding]; other site
761193007033	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
761193007034	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193007035	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
761193007036	ApbE family; Region: ApbE; pfam02424
761193007037	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
761193007038	Glycosyl hydrolase 43-like family consists of hypothetical proteins; Region: GH43_like_2; cd08994
761193007039	active site
761193007040	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
761193007041	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u1; cd11477
761193007042	Na binding site [ion binding]; other site
761193007043	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
761193007044	beta-D-glucuronidase; Provisional; Region: PRK10150
761193007045	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
761193007046	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
761193007047	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
761193007048	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
761193007049	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4876
761193007050	gamma-glutamyl kinase; Provisional; Region: PRK05429
761193007051	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
761193007052	nucleotide binding site [chemical binding]; other site
761193007053	homotetrameric interface [polypeptide binding]; other site
761193007054	putative phosphate binding site [ion binding]; other site
761193007055	putative allosteric binding site; other site
761193007056	PUA domain; Region: PUA; pfam01472
761193007057	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
761193007058	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
761193007059	putative dimer interface [polypeptide binding]; other site
761193007060	RDD family; Region: RDD; pfam06271
761193007061	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
761193007062	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
761193007063	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
761193007064	tetramer interface [polypeptide binding]; other site
761193007065	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193007066	catalytic residue [active]
761193007067	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193007068	Protein of unknown function (DUF502); Region: DUF502; pfam04367
761193007069	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
761193007070	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
761193007071	Mg++ binding site [ion binding]; other site
761193007072	putative catalytic motif [active]
761193007073	substrate binding site [chemical binding]; other site
761193007074	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
761193007075	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
761193007076	metal-binding site
761193007077	putative acyl transferase; Provisional; Region: PRK10502
761193007078	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
761193007079	putative trimer interface [polypeptide binding]; other site
761193007080	putative active site [active]
761193007081	putative substrate binding site [chemical binding]; other site
761193007082	putative CoA binding site [chemical binding]; other site
761193007083	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193007084	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
761193007085	putative metal binding site; other site
761193007086	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
761193007087	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
761193007088	hinge; other site
761193007089	active site
761193007090	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
761193007091	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193007092	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193007093	Walker A/P-loop; other site
761193007094	ATP binding site [chemical binding]; other site
761193007095	Q-loop/lid; other site
761193007096	ABC transporter signature motif; other site
761193007097	Walker B; other site
761193007098	D-loop; other site
761193007099	H-loop/switch region; other site
761193007100	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
761193007101	putative catalytic site [active]
761193007102	putative metal binding site [ion binding]; other site
761193007103	putative phosphate binding site [ion binding]; other site
761193007104	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193007105	SusD family; Region: SusD; pfam07980
761193007106	Secretin and TonB N terminus short domain; Region: STN; pfam07660
761193007107	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193007108	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193007109	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193007110	FecR protein; Region: FecR; pfam04773
761193007111	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193007112	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193007113	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193007114	DNA binding residues [nucleotide binding]
761193007115	hypothetical protein; Provisional; Region: PRK08262
761193007116	M20 Peptidase, carboxypeptidase yscS; Region: M20_yscS; cd05674
761193007117	metal binding site [ion binding]; metal-binding site
761193007118	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
761193007119	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
761193007120	folate binding site [chemical binding]; other site
761193007121	NADP+ binding site [chemical binding]; other site
761193007122	Cytochrome c; Region: Cytochrom_C; cl11414
761193007123	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193007124	putative active site [active]
761193007125	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
761193007126	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193007127	This family is most closely related to the GT1 family of glycosyltransferases. wcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis; Region: GT1_wcfI_like; cd03825
761193007128	11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs; Region: 11beta-HSD1_like_SDR_c; cd05332
761193007129	short chain dehydrogenase; Provisional; Region: PRK06181
761193007130	NADP binding site [chemical binding]; other site
761193007131	homodimer interface [polypeptide binding]; other site
761193007132	substrate binding site [chemical binding]; other site
761193007133	active site
761193007134	CAAX protease self-immunity; Region: Abi; pfam02517
761193007135	Predicted membrane protein [Function unknown]; Region: COG4420
761193007136	acetyl-CoA synthetase; Provisional; Region: PRK00174
761193007137	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
761193007138	active site
761193007139	CoA binding site [chemical binding]; other site
761193007140	acyl-activating enzyme (AAE) consensus motif; other site
761193007141	AMP binding site [chemical binding]; other site
761193007142	acetate binding site [chemical binding]; other site
761193007143	KEGG: psn:Pedsa_0270 hypothetical protein; SPTR:  uncharacterized protein
761193007144	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193007145	putative substrate translocation pore; other site
761193007146	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193007147	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
761193007148	Coenzyme A binding pocket [chemical binding]; other site
761193007149	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
761193007150	Domain of unknown function DUF20; Region: UPF0118; pfam01594
761193007151	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
761193007152	dimerization interface [polypeptide binding]; other site
761193007153	metal binding site [ion binding]; metal-binding site
761193007154	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
761193007155	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
761193007156	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
761193007157	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
761193007158	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
761193007159	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
761193007160	carboxyltransferase (CT) interaction site; other site
761193007161	biotinylation site [posttranslational modification]; other site
761193007162	elongation factor P; Validated; Region: PRK00529
761193007163	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
761193007164	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
761193007165	RNA binding site [nucleotide binding]; other site
761193007166	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
761193007167	RNA binding site [nucleotide binding]; other site
761193007168	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
761193007169	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
761193007170	dimer interface [polypeptide binding]; other site
761193007171	active site
761193007172	CoA binding pocket [chemical binding]; other site
761193007173	putative phosphate acyltransferase; Provisional; Region: PRK05331
761193007174	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
761193007175	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193007176	GPH family sucrose/H+ symporter; Region: GPH_sucrose; TIGR01301
761193007177	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193007178	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193007179	Uncharacterized protein conserved in bacteria (DUF2141); Region: DUF2141; pfam09912
761193007180	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
761193007181	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193007182	Fn3 associated; Region: Fn3_assoc; pfam13287
761193007183	Protein of unknown function (DUF1501); Region: DUF1501; pfam07394
761193007184	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193007185	Protein of unknown function (DUF1549); Region: PSCyt2; pfam07583
761193007186	Protein of unknown function (DUF1553); Region: PSD1; pfam07587
761193007187	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
761193007188	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
761193007189	Protein of unknown function (DUF433); Region: DUF433; pfam04255
761193007190	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4634
761193007191	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
761193007192	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193007193	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
761193007194	Walker A/P-loop; other site
761193007195	ATP binding site [chemical binding]; other site
761193007196	Q-loop/lid; other site
761193007197	ABC transporter signature motif; other site
761193007198	Walker B; other site
761193007199	D-loop; other site
761193007200	H-loop/switch region; other site
761193007201	InterPro IPR001818; KEGG: lby:Lbys_1926 peptidase m10a and m12b matrixin and adamalysin; PFAM: Peptidase M10A/M12B, matrixin/adamalysin; SPTR: Peptidase M10A and M12B matrixin and adamalysin
761193007202	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
761193007203	active site
761193007204	active site
761193007205	Pirin-related protein [General function prediction only]; Region: COG1741
761193007206	Intradiol dioxygenase supgroup. Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. They break the catechol C1-C2 bond and utilize Fe3+, as opposed to  the...; Region: intradiol_dioxygenase_like; cd03457
761193007207	putative active site [active]
761193007208	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
761193007209	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cd00136
761193007210	protein binding site [polypeptide binding]; other site
761193007211	C-terminal processing peptidase-like; serine protease family S41; Region: Peptidase_S41_CPP_like; cd07561
761193007212	Catalytic dyad [active]
761193007213	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193007214	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193007215	active site
761193007216	phosphorylation site [posttranslational modification]
761193007217	intermolecular recognition site; other site
761193007218	dimerization interface [polypeptide binding]; other site
761193007219	LytTr DNA-binding domain; Region: LytTR; smart00850
761193007220	Histidine kinase; Region: His_kinase; pfam06580
761193007221	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
761193007222	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193007223	non-specific DNA binding site [nucleotide binding]; other site
761193007224	salt bridge; other site
761193007225	sequence-specific DNA binding site [nucleotide binding]; other site
761193007226	Cupin domain; Region: Cupin_2; pfam07883
761193007227	M28 Zn-Peptidases containing a PA domain insert and associated with a PDZ domain; Region: M28_like_PA_PDZ_associated; cd05663
761193007228	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193007229	metal binding site [ion binding]; metal-binding site
761193007230	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
761193007231	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
761193007232	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193007233	Coenzyme A binding pocket [chemical binding]; other site
761193007234	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
761193007235	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
761193007236	FMN binding site [chemical binding]; other site
761193007237	active site
761193007238	substrate binding site [chemical binding]; other site
761193007239	catalytic residue [active]
761193007240	Predicted transcriptional regulators [Transcription]; Region: COG1733
761193007241	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
761193007242	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
761193007243	Iron-sulfur protein interface; other site
761193007244	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193007245	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193007246	InterPro IPR001845; KEGG: sli:Slin_3050 ArsR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family
761193007247	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193007248	dimerization interface [polypeptide binding]; other site
761193007249	putative DNA binding site [nucleotide binding]; other site
761193007250	putative Zn2+ binding site [ion binding]; other site
761193007251	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193007252	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193007253	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193007254	salt bridge; other site
761193007255	non-specific DNA binding site [nucleotide binding]; other site
761193007256	sequence-specific DNA binding site [nucleotide binding]; other site
761193007257	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
761193007258	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
761193007259	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
761193007260	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193007261	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193007262	DNA binding residues [nucleotide binding]
761193007263	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193007264	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193007265	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193007266	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
761193007267	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193007268	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193007269	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193007270	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193007271	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193007272	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193007273	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193007274	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193007275	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193007276	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
761193007277	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193007278	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
761193007279	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193007280	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193007281	Neutral/alkaline non-lysosomal ceramidase; Region: Ceramidase_alk; cl04712
761193007282	PhoPQ-activated pathogenicity-related protein; Region: PhoPQ_related; pfam10142
761193007283	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193007284	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
761193007285	Glycerophosphodiester phosphodiesterase domain of Agrobacterium tumefaciens and similar proteins; Region: GDPD_AtGDE_like; cd08566
761193007286	putative active site [active]
761193007287	catalytic site [active]
761193007288	putative metal binding site [ion binding]; other site
761193007289	oligomer interface [polypeptide binding]; other site
761193007290	Glycerophosphodiester phosphodiesterase domain of Agrobacterium tumefaciens and similar proteins; Region: GDPD_AtGDE_like; cd08566
761193007291	Glycerophosphoryl diester phosphodiesterase family; Region: GDPD; pfam03009
761193007292	putative active site [active]
761193007293	catalytic site [active]
761193007294	putative metal binding site [ion binding]; other site
761193007295	oligomer interface [polypeptide binding]; other site
761193007296	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
761193007297	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
761193007298	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193007299	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193007300	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193007301	active site
761193007302	metal binding site [ion binding]; metal-binding site
761193007303	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
761193007304	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
761193007305	ATP binding site [chemical binding]; other site
761193007306	Mg++ binding site [ion binding]; other site
761193007307	motif III; other site
761193007308	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193007309	nucleotide binding region [chemical binding]; other site
761193007310	ATP-binding site [chemical binding]; other site
761193007311	Cytochrome c; Region: Cytochrom_C; cl11414
761193007312	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193007313	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
761193007314	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193007315	metal binding site [ion binding]; metal-binding site
761193007316	substrate binding pocket [chemical binding]; other site
761193007317	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
761193007318	Gram-negative bacterial tonB protein; Region: TonB; cl10048
761193007319	Putative esterase; Region: Esterase; pfam00756
761193007320	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193007321	Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide...; Region: CASc; cl00042
761193007322	Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to...; Region: TUDOR; cd04508
761193007323	dimethylated arginine/lysine binding site [chemical binding]; other site
761193007324	SnoaL-like domain; Region: SnoaL_3; pfam13474
761193007325	Protein of unknown function (DUF4256); Region: DUF4256; pfam14066
761193007326	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
761193007327	COGs: COG3324 protein related to lactoylglutathione lyase; InterPro IPR004360; KEGG: fbc:FB2170_15693 hypothetical protein; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR:  uncharacterized protein
761193007328	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193007329	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
761193007330	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
761193007331	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
761193007332	NADP binding site [chemical binding]; other site
761193007333	dimer interface [polypeptide binding]; other site
761193007334	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
761193007335	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
761193007336	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
761193007337	NADP binding site [chemical binding]; other site
761193007338	active site
761193007339	steroid binding site; other site
761193007340	Predicted transcriptional regulators [Transcription]; Region: COG1733
761193007341	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
761193007342	KEGG: dfe:Dfer_3212 hypothetical protein; SPTR:  uncharacterized protein
761193007343	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
761193007344	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
761193007345	inhibitor-cofactor binding pocket; inhibition site
761193007346	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193007347	catalytic residue [active]
761193007348	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
761193007349	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
761193007350	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
761193007351	Glycosyl hydrolase family 67 N-terminus; Region: Glyco_hydro_67N; pfam03648
761193007352	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
761193007353	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
761193007354	inhibitor site; inhibition site
761193007355	active site
761193007356	dimer interface [polypeptide binding]; other site
761193007357	catalytic residue [active]
761193007358	COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: dfe:Dfer_1871 alpha/beta hydrolase fold protein; PFAM: Alpha/beta hydrolase fold-1; SPTR:  uncharacterized protein
761193007359	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193007360	Erythromycin esterase; Region: Erythro_esteras; pfam05139
761193007361	Histidine kinase; Region: His_kinase; pfam06580
761193007362	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193007363	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193007364	active site
761193007365	phosphorylation site [posttranslational modification]
761193007366	intermolecular recognition site; other site
761193007367	dimerization interface [polypeptide binding]; other site
761193007368	LytTr DNA-binding domain; Region: LytTR; smart00850
761193007369	InterPro IPR010496; KEGG: dfe:Dfer_1397 glycosyl hydrolase 32 domain protein; PFAM: Protein of unknown function DUF1080; SPTR: Glycosyl hydrolase 32 domain protein
761193007370	Glycosyl hydrolase families 32 and 68, which for the clan GH-J; Region: GH_J; cd08979
761193007371	active site
761193007372	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193007373	Chromate resistance exported protein; Region: Chrome_Resist; pfam09828
761193007374	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193007375	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193007376	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
761193007377	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
761193007378	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193007379	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
761193007380	active site
761193007381	homotetramer interface [polypeptide binding]; other site
761193007382	homodimer interface [polypeptide binding]; other site
761193007383	Protein of unknown function (DUF3500); Region: DUF3500; pfam12006
761193007384	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193007385	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193007386	Predicted integral membrane protein [Function unknown]; Region: COG5616
761193007387	TPR repeat; Region: TPR_11; pfam13414
761193007388	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193007389	binding surface
761193007390	TPR motif; other site
761193007391	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193007392	TPR motif; other site
761193007393	binding surface
761193007394	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193007395	TPR motif; other site
761193007396	binding surface
761193007397	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
761193007398	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
761193007399	putative active site [active]
761193007400	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193007401	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193007402	Walker A/P-loop; other site
761193007403	ATP binding site [chemical binding]; other site
761193007404	Q-loop/lid; other site
761193007405	ABC transporter signature motif; other site
761193007406	Walker B; other site
761193007407	D-loop; other site
761193007408	H-loop/switch region; other site
761193007409	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
761193007410	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193007411	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cl17706
761193007412	substrate binding site [chemical binding]; other site
761193007413	catalytic residues [active]
761193007414	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
761193007415	putative dimerization interface [polypeptide binding]; other site
761193007416	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
761193007417	putative ligand binding site [chemical binding]; other site
761193007418	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193007419	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193007420	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
761193007421	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193007422	putative substrate translocation pore; other site
761193007423	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
761193007424	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
761193007425	nucleotide binding site [chemical binding]; other site
761193007426	Putative carbohydrate binding domain; Region: CHB_HEX; cl03918
761193007427	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
761193007428	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
761193007429	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
761193007430	active site
761193007431	C-terminal Early set domain associated with the catalytic domain of chitobiase (also called N-acetylglucosaminidase); Region: E_set_Chitobiase_C; cd02847
761193007432	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
761193007433	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193007434	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193007435	active site
761193007436	metal binding site [ion binding]; metal-binding site
761193007437	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
761193007438	active site
761193007439	metal binding site [ion binding]; metal-binding site
761193007440	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193007441	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193007442	active site
761193007443	metal binding site [ion binding]; metal-binding site
761193007444	InterPro IPR006311:IPR012577; KEGG: shg:Sph21_4452 NIPSNAP family containing protein; PFAM: NIPSNAP; SPTR: NIPSNAP family containing protein
761193007445	NIPSNAP; Region: NIPSNAP; pfam07978
761193007446	NIPSNAP; Region: NIPSNAP; pfam07978
761193007447	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
761193007448	PQQ-like domain; Region: PQQ_2; pfam13360
761193007449	Trp docking motif [polypeptide binding]; other site
761193007450	putative active site [active]
761193007451	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193007452	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
761193007453	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
761193007454	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193007455	binding surface
761193007456	TPR repeat; Region: TPR_11; pfam13414
761193007457	TPR motif; other site
761193007458	Tetratricopeptide repeat; Region: TPR_16; pfam13432
761193007459	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193007460	binding surface
761193007461	TPR motif; other site
761193007462	TPR repeat; Region: TPR_11; pfam13414
761193007463	aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381
761193007464	Pseudomonas putida Aldehyde dehydrogenase AlkH-like; Region: ALDH_AlkH-like; cd07134
761193007465	NAD(P) binding site [chemical binding]; other site
761193007466	catalytic residues [active]
761193007467	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193007468	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193007469	non-specific DNA binding site [nucleotide binding]; other site
761193007470	salt bridge; other site
761193007471	sequence-specific DNA binding site [nucleotide binding]; other site
761193007472	short chain dehydrogenase; Provisional; Region: PRK06179
761193007473	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
761193007474	NADP binding site [chemical binding]; other site
761193007475	active site
761193007476	steroid binding site; other site
761193007477	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
761193007478	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193007479	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193007480	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193007481	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
761193007482	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
761193007483	Surface antigen; Region: Bac_surface_Ag; pfam01103
761193007484	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
761193007485	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193007486	putative substrate translocation pore; other site
761193007487	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
761193007488	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
761193007489	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193007490	MG2 domain; Region: A2M_N; pfam01835
761193007491	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193007492	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
761193007493	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
761193007494	GRAS family transcription factor; Region: GRAS; pfam03514
761193007495	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193007496	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
761193007497	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193007498	homodimer interface [polypeptide binding]; other site
761193007499	catalytic residue [active]
761193007500	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
761193007501	Peptidase family M1; Region: Peptidase_M1; pfam01433
761193007502	Zn binding site [ion binding]; other site
761193007503	HEAT repeats; Region: HEAT_2; pfam13646
761193007504	Prodigal; manually curated
761193007505	Prodigal; manually curated
761193007506	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193007507	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193007508	ligand binding site [chemical binding]; other site
761193007509	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193007510	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
761193007511	Ligand binding site; other site
761193007512	Putative Catalytic site; other site
761193007513	DXD motif; other site
761193007514	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
761193007515	Na binding site [ion binding]; other site
761193007516	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
761193007517	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193007518	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193007519	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193007520	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
761193007521	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
761193007522	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193007523	active site
761193007524	metal binding site [ion binding]; metal-binding site
761193007525	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
761193007526	PLD-like domain; Region: PLDc_2; pfam13091
761193007527	putative active site [active]
761193007528	catalytic site [active]
761193007529	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
761193007530	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
761193007531	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
761193007532	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
761193007533	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
761193007534	ligand binding site [chemical binding]; other site
761193007535	homodimer interface [polypeptide binding]; other site
761193007536	NAD(P) binding site [chemical binding]; other site
761193007537	trimer interface B [polypeptide binding]; other site
761193007538	trimer interface A [polypeptide binding]; other site
761193007539	mannonate dehydratase; Region: uxuA; TIGR00695
761193007540	mannonate dehydratase; Provisional; Region: PRK03906
761193007541	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
761193007542	Active site serine [active]
761193007543	KEGG: ipo:Ilyop_2812 protein of unknown function DUF86; SPTR:  uncharacterized protein
761193007544	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
761193007545	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
761193007546	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193007547	Walker A motif; other site
761193007548	ATP binding site [chemical binding]; other site
761193007549	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193007550	Walker B motif; other site
761193007551	arginine finger; other site
761193007552	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
761193007553	Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893
761193007554	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
761193007555	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
761193007556	protein binding site [polypeptide binding]; other site
761193007557	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193007558	Sulfatase; Region: Sulfatase; pfam00884
761193007559	Sulfatase; Region: Sulfatase; cl17466
761193007560	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193007561	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193007562	Sulfatase; Region: Sulfatase; pfam00884
761193007563	Sulfatase; Region: Sulfatase; cl17466
761193007564	TIGR00159 family protein; Region: TIGR00159
761193007565	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
761193007566	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
761193007567	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
761193007568	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
761193007569	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193007570	Walker A/P-loop; other site
761193007571	ATP binding site [chemical binding]; other site
761193007572	Q-loop/lid; other site
761193007573	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
761193007574	ABC transporter signature motif; other site
761193007575	ABC transporter signature motif; other site
761193007576	Walker B; other site
761193007577	Walker B; other site
761193007578	D-loop; other site
761193007579	D-loop; other site
761193007580	H-loop/switch region; other site
761193007581	ABC transporter; Region: ABC_tran_2; pfam12848
761193007582	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193007583	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193007584	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193007585	active site
761193007586	phosphorylation site [posttranslational modification]
761193007587	intermolecular recognition site; other site
761193007588	dimerization interface [polypeptide binding]; other site
761193007589	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
761193007590	DNA binding residues [nucleotide binding]
761193007591	dimerization interface [polypeptide binding]; other site
761193007592	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
761193007593	Histidine kinase; Region: HisKA_3; pfam07730
761193007594	Histidine kinase; Region: HisKA_3; pfam07730
761193007595	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
761193007596	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193007597	ATP binding site [chemical binding]; other site
761193007598	Mg2+ binding site [ion binding]; other site
761193007599	G-X-G motif; other site
761193007600	Archaeal ATPase; Region: Arch_ATPase; pfam01637
761193007601	AAA ATPase domain; Region: AAA_16; pfam13191
761193007602	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
761193007603	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193007604	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193007605	ABC transporter; Region: ABC_tran_2; pfam12848
761193007606	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193007607	glutamine synthetase; Region: PLN02284
761193007608	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
761193007609	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
761193007610	WxcM-like, C-terminal; Region: FdtA; pfam05523
761193007611	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
761193007612	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
761193007613	inhibitor-cofactor binding pocket; inhibition site
761193007614	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193007615	catalytic residue [active]
761193007616	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
761193007617	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
761193007618	Ligand binding site; other site
761193007619	Putative Catalytic site; other site
761193007620	DXD motif; other site
761193007621	Methyltransferase domain; Region: Methyltransf_23; pfam13489
761193007622	N2227-like protein; Region: N2227; pfam07942
761193007623	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193007624	S-adenosylmethionine binding site [chemical binding]; other site
761193007625	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
761193007626	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
761193007627	oligomer interface [polypeptide binding]; other site
761193007628	active site
761193007629	metal binding site [ion binding]; metal-binding site
761193007630	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
761193007631	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193007632	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
761193007633	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193007634	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193007635	Predicted ATPases [General function prediction only]; Region: COG1106
761193007636	RloB-like protein; Region: RloB; pfam13707
761193007637	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
761193007638	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
761193007639	Copper type II ascorbate-dependent monooxygenase, C-terminal domain; Region: Cu2_monoox_C; pfam03712
761193007640	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193007641	PAS domain; Region: PAS_9; pfam13426
761193007642	putative active site [active]
761193007643	heme pocket [chemical binding]; other site
761193007644	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
761193007645	AZL_007920/MXAN_0976 family protein; Region: AZL_007920_fam; TIGR04052
761193007646	Predicted transcriptional regulators [Transcription]; Region: COG1695
761193007647	Transcriptional regulator PadR-like family; Region: PadR; cl17335
761193007648	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
761193007649	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
761193007650	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
761193007651	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
761193007652	GIY-YIG motif/motif A; other site
761193007653	active site
761193007654	catalytic site [active]
761193007655	putative DNA binding site [nucleotide binding]; other site
761193007656	metal binding site [ion binding]; metal-binding site
761193007657	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
761193007658	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
761193007659	DNA binding site [nucleotide binding]
761193007660	bacillithiol system protein YtxJ; Region: B_thiol_YtxJ; TIGR04019
761193007661	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
761193007662	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
761193007663	Transposase IS200 like; Region: Y1_Tnp; cl00848
761193007664	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193007665	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
761193007666	active site
761193007667	NTP binding site [chemical binding]; other site
761193007668	metal binding triad [ion binding]; metal-binding site
761193007669	antibiotic binding site [chemical binding]; other site
761193007670	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
761193007671	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
761193007672	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
761193007673	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
761193007674	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
761193007675	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
761193007676	substrate binding pocket [chemical binding]; other site
761193007677	chain length determination region; other site
761193007678	substrate-Mg2+ binding site; other site
761193007679	catalytic residues [active]
761193007680	aspartate-rich region 1; other site
761193007681	active site lid residues [active]
761193007682	aspartate-rich region 2; other site
761193007683	hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234
761193007684	HPP family; Region: HPP; pfam04982
761193007685	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
761193007686	fumarate hydratase; Reviewed; Region: fumC; PRK00485
761193007687	Class II fumarases; Region: Fumarase_classII; cd01362
761193007688	active site
761193007689	tetramer interface [polypeptide binding]; other site
761193007690	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193007691	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193007692	putative substrate translocation pore; other site
761193007693	PspC domain; Region: PspC; pfam04024
761193007694	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193007695	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193007696	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
761193007697	Fasciclin domain; Region: Fasciclin; pfam02469
761193007698	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
761193007699	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193007700	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193007701	catalytic residue [active]
761193007702	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
761193007703	oligomeric interface; other site
761193007704	putative active site [active]
761193007705	homodimer interface [polypeptide binding]; other site
761193007706	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193007707	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
761193007708	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193007709	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193007710	metal binding site [ion binding]; metal-binding site
761193007711	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193007712	AAA domain; Region: AAA_21; pfam13304
761193007713	Walker A/P-loop; other site
761193007714	ATP binding site [chemical binding]; other site
761193007715	helicase 45; Provisional; Region: PTZ00424
761193007716	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
761193007717	ATP binding site [chemical binding]; other site
761193007718	Mg++ binding site [ion binding]; other site
761193007719	motif III; other site
761193007720	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193007721	nucleotide binding region [chemical binding]; other site
761193007722	ATP-binding site [chemical binding]; other site
761193007723	TPR repeat; Region: TPR_11; pfam13414
761193007724	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193007725	TPR motif; other site
761193007726	binding surface
761193007727	TPR repeat; Region: TPR_11; pfam13414
761193007728	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193007729	Coenzyme A binding pocket [chemical binding]; other site
761193007730	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
761193007731	Permease; Region: Permease; pfam02405
761193007732	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
761193007733	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
761193007734	Walker A/P-loop; other site
761193007735	ATP binding site [chemical binding]; other site
761193007736	Q-loop/lid; other site
761193007737	ABC transporter signature motif; other site
761193007738	Walker B; other site
761193007739	D-loop; other site
761193007740	H-loop/switch region; other site
761193007741	mce related protein; Region: MCE; pfam02470
761193007742	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
761193007743	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
761193007744	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
761193007745	active site
761193007746	FMN binding site [chemical binding]; other site
761193007747	substrate binding site [chemical binding]; other site
761193007748	homotetramer interface [polypeptide binding]; other site
761193007749	catalytic residue [active]
761193007750	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
761193007751	Ligand Binding Site [chemical binding]; other site
761193007752	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
761193007753	active site
761193007754	Uncharacterized hypothetical proteins similar to the catalytic domains of Phosphoinositide-specific phospholipaseand Glycerophosphodiester phosphodiesterases; Region: PI-PLCc_GDPD_SF_unchar3; cd08577
761193007755	putative active site [active]
761193007756	catalytic site [active]
761193007757	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193007758	non-specific DNA binding site [nucleotide binding]; other site
761193007759	salt bridge; other site
761193007760	sequence-specific DNA binding site [nucleotide binding]; other site
761193007761	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; pfam09907
761193007762	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
761193007763	Domain of unknown function (DUF1793); Region: DUF1793; pfam08760
761193007764	homogentisate 1,2-dioxygenase; Region: HgmA; cl17306
761193007765	fumarylacetoacetase; Region: fum_ac_acetase; TIGR01266
761193007766	Domain of unknown function (DUF1969); Region: DUF1969; pfam09298
761193007767	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
761193007768	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
761193007769	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
761193007770	active site
761193007771	catalytic triad [active]
761193007772	oxyanion hole [active]
761193007773	NRDE protein; Region: NRDE; cl01315
761193007774	YceI-like domain; Region: YceI; pfam04264
761193007775	Electron transfer DM13; Region: DM13; pfam10517
761193007776	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193007777	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193007778	ligand binding site [chemical binding]; other site
761193007779	flexible hinge region; other site
761193007780	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
761193007781	putative switch regulator; other site
761193007782	non-specific DNA interactions [nucleotide binding]; other site
761193007783	DNA binding site [nucleotide binding]
761193007784	sequence specific DNA binding site [nucleotide binding]; other site
761193007785	putative cAMP binding site [chemical binding]; other site
761193007786	ATP-grasp domain; Region: ATP-grasp_4; cl17255
761193007787	Putative esterase; Region: Esterase; pfam00756
761193007788	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193007789	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
761193007790	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
761193007791	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
761193007792	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
761193007793	C-terminal peptidase (prc); Region: prc; TIGR00225
761193007794	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
761193007795	protein binding site [polypeptide binding]; other site
761193007796	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
761193007797	Catalytic dyad [active]
761193007798	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
761193007799	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
761193007800	dimer interface [polypeptide binding]; other site
761193007801	[2Fe-2S] cluster binding site [ion binding]; other site
761193007802	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
761193007803	xylose isomerase; Provisional; Region: PRK05474
761193007804	xylose isomerase; Region: xylose_isom_A; TIGR02630
761193007805	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
761193007806	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
761193007807	inhibitor site; inhibition site
761193007808	active site
761193007809	dimer interface [polypeptide binding]; other site
761193007810	catalytic residue [active]
761193007811	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
761193007812	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
761193007813	OPT oligopeptide transporter protein; Region: OPT; cl14607
761193007814	putative oligopeptide transporter, OPT family; Region: TIGR00733
761193007815	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
761193007816	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193007817	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193007818	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193007819	Outer membrane efflux protein; Region: OEP; pfam02321
761193007820	Outer membrane efflux protein; Region: OEP; pfam02321
761193007821	Domain of unknown function (DUF4260); Region: DUF4260; pfam14079
761193007822	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193007823	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193007824	WHG domain; Region: WHG; pfam13305
761193007825	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
761193007826	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
761193007827	active site
761193007828	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
761193007829	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
761193007830	RNA binding site [nucleotide binding]; other site
761193007831	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
761193007832	RNA binding site [nucleotide binding]; other site
761193007833	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
761193007834	RNA binding site [nucleotide binding]; other site
761193007835	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
761193007836	RNA binding site [nucleotide binding]; other site
761193007837	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
761193007838	RNA binding site [nucleotide binding]; other site
761193007839	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
761193007840	Cytochrome c; Region: Cytochrom_C; pfam00034
761193007841	Heme-binding domain of the class III cytochrome C family and related proteins; Region: Cytochrom_C3; cd08168
761193007842	heme-binding residues [chemical binding]; other site
761193007843	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
761193007844	molybdopterin cofactor binding site; other site
761193007845	The MopB_CT_PHLH CD includes a group of related uncharacterized putative hydrogenase-like homologs (PHLH) of molybdopterin binding proteins. This CD is of the PHLH region homologous to the conserved molybdopterin-binding C-terminal (MopB_CT) region...; Region: MopB_CT_PHLH; cd02784
761193007846	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
761193007847	4Fe-4S binding domain; Region: Fer4; cl02805
761193007848	Polysulphide reductase [Energy production and conversion]; Region: COG5557; cl17901
761193007849	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
761193007850	Protein of unknown function (DUF3341); Region: DUF3341; pfam11821
761193007851	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
761193007852	cytochrome c oxidase, subunit II; Region: CoxB; TIGR02866
761193007853	Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790
761193007854	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
761193007855	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
761193007856	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
761193007857	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
761193007858	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
761193007859	protoheme IX farnesyltransferase; Region: cyoE_ctaB; TIGR01473
761193007860	UbiA prenyltransferase family; Region: UbiA; pfam01040
761193007861	Heme-copper oxidase subunit III subfamily. Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane; Region: Heme_Cu_Oxidase_III_2; cd02865
761193007862	Subunit I/III interface [polypeptide binding]; other site
761193007863	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
761193007864	Subunit I/III interface [polypeptide binding]; other site
761193007865	Prokaryotic Cytochrome C oxidase subunit IV; Region: COX4_pro; pfam03626
761193007866	Protein of unknown function (DUF420); Region: DUF420; pfam04238
761193007867	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
761193007868	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193007869	S-adenosylmethionine binding site [chemical binding]; other site
761193007870	Haemolytic domain; Region: Haemolytic; pfam01809
761193007871	TM2 domain; Region: TM2; pfam05154
761193007872	cytidylate kinase; Provisional; Region: cmk; PRK00023
761193007873	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
761193007874	CMP-binding site; other site
761193007875	The sites determining sugar specificity; other site
761193007876	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
761193007877	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193007878	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
761193007879	Surface antigen; Region: Bac_surface_Ag; pfam01103
761193007880	Domain of unknown function DUF11; Region: DUF11; cl17728
761193007881	Domain of unknown function DUF11; Region: DUF11; cl17728
761193007882	Domain of unknown function DUF11; Region: DUF11; pfam01345
761193007883	conserved repeat domain; Region: B_ant_repeat; TIGR01451
761193007884	Domain of unknown function DUF11; Region: DUF11; pfam01345
761193007885	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193007886	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
761193007887	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193007888	binding surface
761193007889	TPR motif; other site
761193007890	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
761193007891	CD36 family; Region: CD36; pfam01130
761193007892	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193007893	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193007894	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193007895	ligand binding site [chemical binding]; other site
761193007896	Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640
761193007897	Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640
761193007898	Prodigal; manually curated
761193007899	InterPro IPR002559; KEGG: amr:AM1_3283 IS4 family transposase; PFAM: Transposase, IS4-like; SPTR: Transposase, IS4 family; manually curated
761193007900	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
761193007901	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
761193007902	Homeodomain-like domain; Region: HTH_23; pfam13384
761193007903	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193007904	Homeodomain-like domain; Region: HTH_32; pfam13565
761193007905	Winged helix-turn helix; Region: HTH_33; pfam13592
761193007906	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193007907	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193007908	InterPro IPR006143; KEGG: sli:Slin_0782 hypothetical protein; PFAM: Secretion protein HlyD; SPTR:  uncharacterized protein
761193007909	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
761193007910	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193007911	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
761193007912	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
761193007913	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
761193007914	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
761193007915	TPP-binding site [chemical binding]; other site
761193007916	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
761193007917	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
761193007918	E3 interaction surface; other site
761193007919	lipoyl attachment site [posttranslational modification]; other site
761193007920	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
761193007921	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
761193007922	E3 interaction surface; other site
761193007923	lipoyl attachment site [posttranslational modification]; other site
761193007924	e3 binding domain; Region: E3_binding; pfam02817
761193007925	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
761193007926	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
761193007927	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
761193007928	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193007929	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
761193007930	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
761193007931	Sm and related proteins; Region: Sm_like; cl00259
761193007932	ribosome maturation protein RimP; Reviewed; Region: PRK00092
761193007933	heptamer interface [polypeptide binding]; other site
761193007934	Sm1 motif; other site
761193007935	hexamer interface [polypeptide binding]; other site
761193007936	RNA binding site [nucleotide binding]; other site
761193007937	Sm2 motif; other site
761193007938	transcription termination factor NusA; Region: NusA; TIGR01953
761193007939	NusA N-terminal domain; Region: NusA_N; pfam08529
761193007940	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
761193007941	RNA binding site [nucleotide binding]; other site
761193007942	homodimer interface [polypeptide binding]; other site
761193007943	NusA-like KH domain; Region: KH_5; pfam13184
761193007944	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
761193007945	G-X-X-G motif; other site
761193007946	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
761193007947	translation initiation factor IF-2; Region: IF-2; TIGR00487
761193007948	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
761193007949	G1 box; other site
761193007950	putative GEF interaction site [polypeptide binding]; other site
761193007951	GTP/Mg2+ binding site [chemical binding]; other site
761193007952	Switch I region; other site
761193007953	G2 box; other site
761193007954	G3 box; other site
761193007955	Switch II region; other site
761193007956	G4 box; other site
761193007957	G5 box; other site
761193007958	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
761193007959	Translation-initiation factor 2; Region: IF-2; pfam11987
761193007960	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
761193007961	CAAX protease self-immunity; Region: Abi; pfam02517
761193007962	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
761193007963	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
761193007964	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193007965	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
761193007966	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
761193007967	putative active site [active]
761193007968	putative metal binding site [ion binding]; other site
761193007969	Cupin domain; Region: Cupin_2; cl17218
761193007970	metal-dependent hydrolase; Provisional; Region: PRK13291
761193007971	DinB superfamily; Region: DinB_2; pfam12867
761193007972	Uncharacterized conserved protein [Function unknown]; Region: COG3339
761193007973	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
761193007974	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
761193007975	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
761193007976	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
761193007977	N-acetyl-D-glucosamine binding site [chemical binding]; other site
761193007978	catalytic residue [active]
761193007979	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193007980	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193007981	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
761193007982	HNH endonuclease; Region: HNH_2; pfam13391
761193007983	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193007984	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193007985	LytTr DNA-binding domain; Region: LytTR; pfam04397
761193007986	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
761193007987	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
761193007988	dimerization interface [polypeptide binding]; other site
761193007989	PAS domain; Region: PAS; smart00091
761193007990	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193007991	dimer interface [polypeptide binding]; other site
761193007992	phosphorylation site [posttranslational modification]
761193007993	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193007994	ATP binding site [chemical binding]; other site
761193007995	Mg2+ binding site [ion binding]; other site
761193007996	G-X-G motif; other site
761193007997	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
761193007998	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
761193007999	Ligand Binding Site [chemical binding]; other site
761193008000	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
761193008001	K+-transporting ATPase, c chain; Region: KdpC; cl00944
761193008002	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
761193008003	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
761193008004	Soluble P-type ATPase [General function prediction only]; Region: COG4087
761193008005	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
761193008006	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
761193008007	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008008	active site
761193008009	phosphorylation site [posttranslational modification]
761193008010	intermolecular recognition site; other site
761193008011	dimerization interface [polypeptide binding]; other site
761193008012	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193008013	Walker B motif; other site
761193008014	arginine finger; other site
761193008015	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
761193008016	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
761193008017	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
761193008018	active site
761193008019	tetramer interface; other site
761193008020	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193008021	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
761193008022	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
761193008023	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193008024	metal binding site [ion binding]; metal-binding site
761193008025	homoserine kinase; Provisional; Region: PRK01212
761193008026	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
761193008027	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
761193008028	HEPN domain; Region: HEPN; cl00824
761193008029	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
761193008030	NTP binding site [chemical binding]; other site
761193008031	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
761193008032	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193008033	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
761193008034	catalytic center binding site [active]
761193008035	ATP binding site [chemical binding]; other site
761193008036	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
761193008037	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
761193008038	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
761193008039	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193008040	Walker A motif; other site
761193008041	ATP binding site [chemical binding]; other site
761193008042	Walker B motif; other site
761193008043	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
761193008044	Domain of unknown function (DUF4293); Region: DUF4293; pfam14126
761193008045	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
761193008046	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193008047	ATP binding site [chemical binding]; other site
761193008048	putative Mg++ binding site [ion binding]; other site
761193008049	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193008050	nucleotide binding region [chemical binding]; other site
761193008051	ATP-binding site [chemical binding]; other site
761193008052	RQC domain; Region: RQC; pfam09382
761193008053	HRDC domain; Region: HRDC; pfam00570
761193008054	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
761193008055	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
761193008056	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
761193008057	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
761193008058	PSP1 C-terminal conserved region; Region: PSP1; cl00770
761193008059	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193008060	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193008061	non-specific DNA binding site [nucleotide binding]; other site
761193008062	salt bridge; other site
761193008063	sequence-specific DNA binding site [nucleotide binding]; other site
761193008064	KEGG: dfe:Dfer_5247 peptidase C39 bacteriocin processing; SPTR: Peptidase C39 bacteriocin processing
761193008065	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
761193008066	Vitamin K epoxide reductase (VKOR) family in bacteria; Region: VKOR_4; cd12921
761193008067	putative active site [active]
761193008068	redox center [active]
761193008069	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
761193008070	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
761193008071	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
761193008072	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
761193008073	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
761193008074	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
761193008075	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
761193008076	active site
761193008077	metal binding site [ion binding]; metal-binding site
761193008078	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
761193008079	mce related protein; Region: MCE; pfam02470
761193008080	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
761193008081	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
761193008082	(2R)-phospho-3-sulfolactate synthase (ComA); Region: ComA; pfam02679
761193008083	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
761193008084	tetramer interface [polypeptide binding]; other site
761193008085	TPP-binding site [chemical binding]; other site
761193008086	heterodimer interface [polypeptide binding]; other site
761193008087	phosphorylation loop region [posttranslational modification]
761193008088	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
761193008089	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
761193008090	PYR/PP interface [polypeptide binding]; other site
761193008091	dimer interface [polypeptide binding]; other site
761193008092	TPP binding site [chemical binding]; other site
761193008093	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
761193008094	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
761193008095	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193008096	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193008097	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
761193008098	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
761193008099	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193008100	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193008101	ligand binding site [chemical binding]; other site
761193008102	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193008103	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193008104	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193008105	Outer membrane efflux protein; Region: OEP; pfam02321
761193008106	Outer membrane efflux protein; Region: OEP; pfam02321
761193008107	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193008108	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193008109	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
761193008110	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
761193008111	Asp-box motif; other site
761193008112	multidrug efflux protein; Reviewed; Region: PRK01766
761193008113	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
761193008114	cation binding site [ion binding]; other site
761193008115	chaperone protein DnaJ; Provisional; Region: PRK14289
761193008116	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
761193008117	HSP70 interaction site [polypeptide binding]; other site
761193008118	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
761193008119	Zn binding sites [ion binding]; other site
761193008120	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
761193008121	dimer interface [polypeptide binding]; other site
761193008122	GrpE; Region: GrpE; pfam01025
761193008123	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
761193008124	dimer interface [polypeptide binding]; other site
761193008125	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
761193008126	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
761193008127	generic binding surface II; other site
761193008128	generic binding surface I; other site
761193008129	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
761193008130	putative catalytic site [active]
761193008131	putative metal binding site [ion binding]; other site
761193008132	putative phosphate binding site [ion binding]; other site
761193008133	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193008134	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
761193008135	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193008136	Sulfatase; Region: Sulfatase; pfam00884
761193008137	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
761193008138	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193008139	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193008140	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193008141	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
761193008142	conserved cys residue [active]
761193008143	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193008144	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193008145	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193008146	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193008147	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193008148	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193008149	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
761193008150	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
761193008151	inhibitor-cofactor binding pocket; inhibition site
761193008152	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193008153	catalytic residue [active]
761193008154	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
761193008155	dihydrodipicolinate synthase; Region: dapA; TIGR00674
761193008156	dimer interface [polypeptide binding]; other site
761193008157	active site
761193008158	catalytic residue [active]
761193008159	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_1; cd06238
761193008160	putative active site [active]
761193008161	Zn binding site [ion binding]; other site
761193008162	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193008163	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193008164	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193008165	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
761193008166	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
761193008167	dinuclear metal binding motif [ion binding]; other site
761193008168	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
761193008169	dinuclear metal binding motif [ion binding]; other site
761193008170	InterPro IPR000182; KEGG: bvu:BVU_1962 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR:  uncharacterized protein
761193008171	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
761193008172	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193008173	Coenzyme A binding pocket [chemical binding]; other site
761193008174	Predicted amidohydrolase [General function prediction only]; Region: COG0388
761193008175	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
761193008176	active site
761193008177	catalytic triad [active]
761193008178	dimer interface [polypeptide binding]; other site
761193008179	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
761193008180	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
761193008181	dimer interface [polypeptide binding]; other site
761193008182	active site
761193008183	heme binding site [chemical binding]; other site
761193008184	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
761193008185	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193008186	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
761193008187	FtsX-like permease family; Region: FtsX; pfam02687
761193008188	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193008189	FtsX-like permease family; Region: FtsX; pfam02687
761193008190	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
761193008191	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
761193008192	active site
761193008193	PHP Thumb interface [polypeptide binding]; other site
761193008194	metal binding site [ion binding]; metal-binding site
761193008195	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
761193008196	generic binding surface II; other site
761193008197	generic binding surface I; other site
761193008198	AAA ATPase domain; Region: AAA_15; pfam13175
761193008199	COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR003661:IPR003594; KEGG: sli:Slin_2864 histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Histidine kinase
761193008200	Cytochrome oxidase assembly protein; Region: COX15-CtaA; cl15852
761193008201	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193008202	dimer interface [polypeptide binding]; other site
761193008203	phosphorylation site [posttranslational modification]
761193008204	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008205	ATP binding site [chemical binding]; other site
761193008206	Mg2+ binding site [ion binding]; other site
761193008207	G-X-G motif; other site
761193008208	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
761193008209	Inorganic H+ pyrophosphatase; Region: H_PPase; pfam03030
761193008210	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193008211	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193008212	ligand binding site [chemical binding]; other site
761193008213	COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dfe:Dfer_5075 polyprenyl synthetase; PFAM: Polyprenyl synthetase; PRIAM: Trans-hexaprenyltranstransferase; SPTR: Polyprenyl synthetase
761193008214	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
761193008215	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
761193008216	substrate binding pocket [chemical binding]; other site
761193008217	chain length determination region; other site
761193008218	substrate-Mg2+ binding site; other site
761193008219	catalytic residues [active]
761193008220	aspartate-rich region 1; other site
761193008221	active site lid residues [active]
761193008222	aspartate-rich region 2; other site
761193008223	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
761193008224	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
761193008225	active site
761193008226	nucleophile elbow; other site
761193008227	putative acetyltransferase; Provisional; Region: PRK03624
761193008228	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193008229	Coenzyme A binding pocket [chemical binding]; other site
761193008230	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
761193008231	active site
761193008232	catalytic triad [active]
761193008233	oxyanion hole [active]
761193008234	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
761193008235	active site
761193008236	phosphorylation site [posttranslational modification]
761193008237	dimerization interface [polypeptide binding]; other site
761193008238	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008239	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008240	active site
761193008241	phosphorylation site [posttranslational modification]
761193008242	intermolecular recognition site; other site
761193008243	dimerization interface [polypeptide binding]; other site
761193008244	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193008245	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
761193008246	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193008247	dimer interface [polypeptide binding]; other site
761193008248	phosphorylation site [posttranslational modification]
761193008249	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008250	ATP binding site [chemical binding]; other site
761193008251	Mg2+ binding site [ion binding]; other site
761193008252	G-X-G motif; other site
761193008253	CHASE3 domain; Region: CHASE3; pfam05227
761193008254	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
761193008255	dimerization interface [polypeptide binding]; other site
761193008256	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
761193008257	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
761193008258	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
761193008259	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008260	ATP binding site [chemical binding]; other site
761193008261	Mg2+ binding site [ion binding]; other site
761193008262	G-X-G motif; other site
761193008263	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008264	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008265	active site
761193008266	phosphorylation site [posttranslational modification]
761193008267	intermolecular recognition site; other site
761193008268	dimerization interface [polypeptide binding]; other site
761193008269	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193008270	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008271	active site
761193008272	phosphorylation site [posttranslational modification]
761193008273	intermolecular recognition site; other site
761193008274	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008275	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008276	active site
761193008277	phosphorylation site [posttranslational modification]
761193008278	intermolecular recognition site; other site
761193008279	dimerization interface [polypeptide binding]; other site
761193008280	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008281	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008282	active site
761193008283	phosphorylation site [posttranslational modification]
761193008284	intermolecular recognition site; other site
761193008285	dimerization interface [polypeptide binding]; other site
761193008286	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
761193008287	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
761193008288	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
761193008289	CheB methylesterase; Region: CheB_methylest; pfam01339
761193008290	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008291	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008292	active site
761193008293	phosphorylation site [posttranslational modification]
761193008294	intermolecular recognition site; other site
761193008295	dimerization interface [polypeptide binding]; other site
761193008296	Family description; Region: VCBS; pfam13517
761193008297	Family description; Region: VCBS; pfam13517
761193008298	Family description; Region: VCBS; pfam13517
761193008299	Family description; Region: VCBS; pfam13517
761193008300	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
761193008301	Cysteine-rich domain; Region: CCG; pfam02754
761193008302	Cysteine-rich domain; Region: CCG; pfam02754
761193008303	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
761193008304	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
761193008305	4Fe-4S binding domain; Region: Fer4; pfam00037
761193008306	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
761193008307	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
761193008308	Neutral/alkaline non-lysosomal ceramidase; Region: Ceramidase_alk; cl04712
761193008309	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193008310	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193008311	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193008312	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193008313	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008314	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008315	active site
761193008316	phosphorylation site [posttranslational modification]
761193008317	intermolecular recognition site; other site
761193008318	dimerization interface [polypeptide binding]; other site
761193008319	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193008320	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008321	ATP binding site [chemical binding]; other site
761193008322	Mg2+ binding site [ion binding]; other site
761193008323	G-X-G motif; other site
761193008324	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008325	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008326	active site
761193008327	phosphorylation site [posttranslational modification]
761193008328	intermolecular recognition site; other site
761193008329	dimerization interface [polypeptide binding]; other site
761193008330	MarR family; Region: MarR_2; cl17246
761193008331	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193008332	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193008333	PAS domain S-box; Region: sensory_box; TIGR00229
761193008334	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193008335	putative active site [active]
761193008336	heme pocket [chemical binding]; other site
761193008337	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193008338	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193008339	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193008340	putative active site [active]
761193008341	heme pocket [chemical binding]; other site
761193008342	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193008343	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193008344	putative active site [active]
761193008345	heme pocket [chemical binding]; other site
761193008346	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193008347	putative active site [active]
761193008348	heme pocket [chemical binding]; other site
761193008349	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193008350	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193008351	dimer interface [polypeptide binding]; other site
761193008352	phosphorylation site [posttranslational modification]
761193008353	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008354	ATP binding site [chemical binding]; other site
761193008355	Mg2+ binding site [ion binding]; other site
761193008356	G-X-G motif; other site
761193008357	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system [Function unknown]; Region: COG4946
761193008358	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193008359	Actin depolymerization factor/cofilin- and gelsolin-like domains; Region: ADF_gelsolin; cl15697
761193008360	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193008361	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
761193008362	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
761193008363	protein binding site [polypeptide binding]; other site
761193008364	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
761193008365	Domain interface; other site
761193008366	Peptide binding site; other site
761193008367	Active site tetrad [active]
761193008368	Topoisomerase IB [DNA replication, recombination, and repair]; Region: COG3569
761193008369	DNA topoisomerase IB, C-terminal catalytic domain. Topoisomerase I promotes the relaxation of both positive and negative DNA superhelical tension by introducing a transient single-stranded break in duplex DNA. This function is vital for the processes of...; Region: Topo_IB_C; cd00659
761193008370	active site
761193008371	DNA binding site [nucleotide binding]
761193008372	Int/Topo IB signature motif; other site
761193008373	catalytic residues [active]
761193008374	short chain dehydrogenase; Provisional; Region: PRK06701
761193008375	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
761193008376	NAD binding site [chemical binding]; other site
761193008377	metal binding site [ion binding]; metal-binding site
761193008378	active site
761193008379	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
761193008380	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193008381	Walker A/P-loop; other site
761193008382	ATP binding site [chemical binding]; other site
761193008383	Q-loop/lid; other site
761193008384	ABC transporter signature motif; other site
761193008385	Walker B; other site
761193008386	D-loop; other site
761193008387	H-loop/switch region; other site
761193008388	TOBE domain; Region: TOBE_2; pfam08402
761193008389	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
761193008390	active site
761193008391	Zn binding site [ion binding]; other site
761193008392	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
761193008393	active site
761193008394	Zn binding site [ion binding]; other site
761193008395	N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653
761193008396	D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics; Region: D-aminoacylase; cd01297
761193008397	active site
761193008398	putative substrate binding pocket [chemical binding]; other site
761193008399	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193008400	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193008401	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193008402	binding surface
761193008403	TPR motif; other site
761193008404	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193008405	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
761193008406	Histidine kinase; Region: HisKA_3; pfam07730
761193008407	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008408	ATP binding site [chemical binding]; other site
761193008409	Mg2+ binding site [ion binding]; other site
761193008410	G-X-G motif; other site
761193008411	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193008412	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
761193008413	putative metal binding site; other site
761193008414	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
761193008415	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
761193008416	homodimer interface [polypeptide binding]; other site
761193008417	substrate-cofactor binding pocket; other site
761193008418	catalytic residue [active]
761193008419	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
761193008420	Domain of unknown function (DUF4281); Region: DUF4281; pfam14108
761193008421	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193008422	putative active site [active]
761193008423	dihydroxy-acid dehydratase; Validated; Region: PRK06131
761193008424	exopolyphosphatase; Region: exo_poly_only; TIGR03706
761193008425	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
761193008426	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
761193008427	YCII-related domain; Region: YCII; cl00999
761193008428	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
761193008429	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193008430	Walker A motif; other site
761193008431	ATP binding site [chemical binding]; other site
761193008432	Walker B motif; other site
761193008433	arginine finger; other site
761193008434	Peptidase family M41; Region: Peptidase_M41; pfam01434
761193008435	Oligomerisation domain; Region: Oligomerisation; pfam02410
761193008436	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
761193008437	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
761193008438	gliding motility-associated lipoprotein GldD; Region: GldD_lipo; TIGR03512
761193008439	prenyltransferase; Reviewed; Region: ubiA; PRK12872
761193008440	UbiA prenyltransferase family; Region: UbiA; pfam01040
761193008441	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
761193008442	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
761193008443	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
761193008444	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
761193008445	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193008446	active site
761193008447	metal binding site [ion binding]; metal-binding site
761193008448	Amidinotransferase; Region: Amidinotransf; cl12043
761193008449	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193008450	putative active site [active]
761193008451	Uncharacterized protein conserved in bacteria containing a pentein-type domain [Function unknown]; Region: COG4874
761193008452	Amidinotransferase; Region: Amidinotransf; pfam02274
761193008453	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
761193008454	D-alanine--D-alanine ligase; Region: D_ala_D_alaTIGR; TIGR01205
761193008455	ATP-grasp domain; Region: ATP-grasp_4; cl17255
761193008456	ATP-grasp domain; Region: ATP-grasp_4; cl17255
761193008457	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
761193008458	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
761193008459	CTP synthetase; Validated; Region: pyrG; PRK05380
761193008460	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
761193008461	Catalytic site [active]
761193008462	active site
761193008463	UTP binding site [chemical binding]; other site
761193008464	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
761193008465	active site
761193008466	putative oxyanion hole; other site
761193008467	catalytic triad [active]
761193008468	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
761193008469	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
761193008470	catalytic motif [active]
761193008471	Zn binding site [ion binding]; other site
761193008472	RibD C-terminal domain; Region: RibD_C; cl17279
761193008473	prephenate dehydrogenase; Validated; Region: PRK08507
761193008474	Prephenate dehydrogenase; Region: PDH; pfam02153
761193008475	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
761193008476	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
761193008477	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
761193008478	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193008479	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
761193008480	active site
761193008481	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
761193008482	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
761193008483	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193008484	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193008485	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
761193008486	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
761193008487	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
761193008488	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193008489	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193008490	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
761193008491	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
761193008492	active site
761193008493	catalytic tetrad [active]
761193008494	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
761193008495	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193008496	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
761193008497	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193008498	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193008499	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
761193008500	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
761193008501	CoA-transferase family III; Region: CoA_transf_3; pfam02515
761193008502	manually curated
761193008503	HTH domain; Region: HTH_11; pfam08279
761193008504	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
761193008505	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
761193008506	CoA-binding site [chemical binding]; other site
761193008507	ATP-binding [chemical binding]; other site
761193008508	Preprotein translocase subunit; Region: YajC; pfam02699
761193008509	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
761193008510	YtxH-like protein; Region: YtxH; pfam12732
761193008511	putative RNA binding site [nucleotide binding]; other site
761193008512	transcription antitermination factor NusB; Region: nusB; TIGR01951
761193008513	recombinase A; Provisional; Region: recA; PRK09354
761193008514	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
761193008515	hexamer interface [polypeptide binding]; other site
761193008516	Walker A motif; other site
761193008517	ATP binding site [chemical binding]; other site
761193008518	Walker B motif; other site
761193008519	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
761193008520	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
761193008521	FAD binding site [chemical binding]; other site
761193008522	homotetramer interface [polypeptide binding]; other site
761193008523	substrate binding pocket [chemical binding]; other site
761193008524	catalytic base [active]
761193008525	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
761193008526	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
761193008527	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
761193008528	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
761193008529	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193008530	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
761193008531	NAD binding site [chemical binding]; other site
761193008532	putative substrate binding site 2 [chemical binding]; other site
761193008533	putative substrate binding site 1 [chemical binding]; other site
761193008534	active site
761193008535	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
761193008536	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
761193008537	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
761193008538	glycyl-tRNA synthetase; Provisional; Region: PRK04173
761193008539	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
761193008540	motif 1; other site
761193008541	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
761193008542	active site
761193008543	motif 2; other site
761193008544	motif 3; other site
761193008545	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
761193008546	anticodon binding site; other site
761193008547	Predicted transcriptional regulators [Transcription]; Region: COG1695
761193008548	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
761193008549	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193008550	putative active site [active]
761193008551	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193008552	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193008553	putative substrate translocation pore; other site
761193008554	CcmB protein; Region: CcmB; cl17444
761193008555	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
761193008556	Protein of unknown function (DUF2281); Region: DUF2281; pfam10047
761193008557	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
761193008558	putative active site [active]
761193008559	CcmE; Region: CcmE; cl00994
761193008560	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
761193008561	Periplasmic lysozyme inhibitor, I-type (PliI) and similar proteins; Region: PliI_like; cd09632
761193008562	dimer interface [polypeptide binding]; other site
761193008563	putative inhibitory loop; other site
761193008564	SnoaL-like domain; Region: SnoaL_3; pfam13474
761193008565	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
761193008566	Putative D-isomer specific 2-hydroxyacid dehydrogenase; Region: 2-Hacid_dh_1; cd05300
761193008567	NAD binding site [chemical binding]; other site
761193008568	ligand binding site [chemical binding]; other site
761193008569	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
761193008570	catalytic site [active]
761193008571	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
761193008572	active site
761193008573	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
761193008574	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
761193008575	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193008576	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193008577	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193008578	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193008579	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
761193008580	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193008581	Prodigal; manually curated
761193008582	COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: sli:Slin_4249 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase
761193008583	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193008584	extended (e) SDRs; Region: SDR_e; cd08946
761193008585	NAD(P) binding site [chemical binding]; other site
761193008586	active site
761193008587	substrate binding site [chemical binding]; other site
761193008588	RES domain; Region: RES; pfam08808
761193008589	Protein of unknown function (DUF2384); Region: DUF2384; cl17718
761193008590	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4642
761193008591	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
761193008592	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193008593	von Willebrand factor type D domain; Region: VWD; cl02516
761193008594	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193008595	Histidine kinase; Region: HisKA_2; pfam07568
761193008596	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
761193008597	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
761193008598	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008599	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008600	active site
761193008601	phosphorylation site [posttranslational modification]
761193008602	intermolecular recognition site; other site
761193008603	dimerization interface [polypeptide binding]; other site
761193008604	LytTr DNA-binding domain; Region: LytTR; smart00850
761193008605	beta-Glucocerebrosidase 2 N terminal; Region: GBA2_N; pfam12215
761193008606	Protein of unknown function, DUF608; Region: DUF608; pfam04685
761193008607	Predicted amidohydrolase [General function prediction only]; Region: COG0388
761193008608	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
761193008609	putative active site [active]
761193008610	catalytic triad [active]
761193008611	putative dimer interface [polypeptide binding]; other site
761193008612	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193008613	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
761193008614	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
761193008615	active site
761193008616	Zn binding site [ion binding]; other site
761193008617	BNR repeat-like domain; Region: BNR_2; pfam13088
761193008618	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
761193008619	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
761193008620	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
761193008621	DXD motif; other site
761193008622	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
761193008623	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
761193008624	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
761193008625	Transposase; Region: DDE_Tnp_ISL3; pfam01610
761193008626	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
761193008627	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193008628	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
761193008629	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
761193008630	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193008631	Coenzyme A binding pocket [chemical binding]; other site
761193008632	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
761193008633	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
761193008634	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
761193008635	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
761193008636	active site
761193008637	Trm112p-like protein; Region: Trm112p; cl01066
761193008638	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
761193008639	thiamine phosphate binding site [chemical binding]; other site
761193008640	active site
761193008641	pyrophosphate binding site [ion binding]; other site
761193008642	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypE; COG0309
761193008643	AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two...; Region: PurM-like1; cd06061
761193008644	dimerization interface [polypeptide binding]; other site
761193008645	putative ATP binding site [chemical binding]; other site
761193008646	Methyltransferase domain; Region: Methyltransf_23; pfam13489
761193008647	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193008648	S-adenosylmethionine binding site [chemical binding]; other site
761193008649	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
761193008650	Asp-box motif; other site
761193008651	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
761193008652	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
761193008653	C-terminal processing peptidase-like; serine protease family S41; Region: Peptidase_S41_CPP_like; cd07561
761193008654	Catalytic dyad [active]
761193008655	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
761193008656	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
761193008657	Walker A/P-loop; other site
761193008658	ATP binding site [chemical binding]; other site
761193008659	Q-loop/lid; other site
761193008660	ABC transporter signature motif; other site
761193008661	Walker B; other site
761193008662	D-loop; other site
761193008663	H-loop/switch region; other site
761193008664	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
761193008665	TPR repeat; Region: TPR_11; pfam13414
761193008666	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193008667	binding surface
761193008668	TPR motif; other site
761193008669	Outer membrane efflux protein; Region: OEP; pfam02321
761193008670	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
761193008671	KEGG: bvu:BVU_1028 hypothetical protein; SPTR:  uncharacterized protein
761193008672	Domain of unknown function (DUF4221); Region: DUF4221; pfam13970
761193008673	Protein of unknown function (DUF433); Region: DUF433; pfam04255
761193008674	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193008675	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193008676	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193008677	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193008678	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
761193008679	DNA binding residues [nucleotide binding]
761193008680	dimerization interface [polypeptide binding]; other site
761193008681	Domain of unknown function (DUF4221); Region: DUF4221; pfam13970
761193008682	CARDB; Region: CARDB; pfam07705
761193008683	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193008684	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
761193008685	Protein export membrane protein; Region: SecD_SecF; cl14618
761193008686	Family of unknown function (DUF490); Region: DUF490; pfam04357
761193008687	UGMP family protein; Validated; Region: PRK09604
761193008688	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
761193008689	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
761193008690	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
761193008691	GAF domain; Region: GAF; pfam01590
761193008692	PAS domain S-box; Region: sensory_box; TIGR00229
761193008693	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193008694	putative active site [active]
761193008695	heme pocket [chemical binding]; other site
761193008696	PAS domain S-box; Region: sensory_box; TIGR00229
761193008697	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193008698	putative active site [active]
761193008699	heme pocket [chemical binding]; other site
761193008700	PAS domain; Region: PAS_9; pfam13426
761193008701	PAS domain S-box; Region: sensory_box; TIGR00229
761193008702	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193008703	putative active site [active]
761193008704	heme pocket [chemical binding]; other site
761193008705	PAS fold; Region: PAS_4; pfam08448
761193008706	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193008707	dimer interface [polypeptide binding]; other site
761193008708	phosphorylation site [posttranslational modification]
761193008709	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008710	ATP binding site [chemical binding]; other site
761193008711	Mg2+ binding site [ion binding]; other site
761193008712	G-X-G motif; other site
761193008713	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193008714	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008715	active site
761193008716	phosphorylation site [posttranslational modification]
761193008717	intermolecular recognition site; other site
761193008718	dimerization interface [polypeptide binding]; other site
761193008719	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193008720	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008721	active site
761193008722	phosphorylation site [posttranslational modification]
761193008723	intermolecular recognition site; other site
761193008724	dimerization interface [polypeptide binding]; other site
761193008725	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193008726	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193008727	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
761193008728	Strictosidine synthase; Region: Str_synth; pfam03088
761193008729	AAA domain; Region: AAA_17; pfam13207
761193008730	LytTr DNA-binding domain; Region: LytTR; smart00850
761193008731	Right handed beta helix region; Region: Beta_helix; pfam13229
761193008732	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193008733	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008734	active site
761193008735	phosphorylation site [posttranslational modification]
761193008736	intermolecular recognition site; other site
761193008737	dimerization interface [polypeptide binding]; other site
761193008738	LytTr DNA-binding domain; Region: LytTR; smart00850
761193008739	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
761193008740	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193008741	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
761193008742	dimer interface [polypeptide binding]; other site
761193008743	phosphorylation site [posttranslational modification]
761193008744	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008745	ATP binding site [chemical binding]; other site
761193008746	Mg2+ binding site [ion binding]; other site
761193008747	G-X-G motif; other site
761193008748	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
761193008749	IHF - DNA interface [nucleotide binding]; other site
761193008750	IHF dimer interface [polypeptide binding]; other site
761193008751	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193008752	ligand binding site [chemical binding]; other site
761193008753	serine racemase; Region: PLN02970
761193008754	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
761193008755	tetramer interface [polypeptide binding]; other site
761193008756	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193008757	catalytic residue [active]
761193008758	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
761193008759	active site
761193008760	dinuclear metal binding site [ion binding]; other site
761193008761	dimerization interface [polypeptide binding]; other site
761193008762	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
761193008763	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
761193008764	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193008765	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193008766	AAA domain; Region: AAA_21; pfam13304
761193008767	Walker A/P-loop; other site
761193008768	ATP binding site [chemical binding]; other site
761193008769	Q-loop/lid; other site
761193008770	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193008771	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193008772	non-specific DNA binding site [nucleotide binding]; other site
761193008773	salt bridge; other site
761193008774	sequence-specific DNA binding site [nucleotide binding]; other site
761193008775	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193008776	active site
761193008777	Int/Topo IB signature motif; other site
761193008778	DNA binding site [nucleotide binding]
761193008779	Virulence-associated protein E; Region: VirE; pfam05272
761193008780	CHC2 zinc finger; Region: zf-CHC2; cl17510
761193008781	Toprim-like; Region: Toprim_2; pfam13155
761193008782	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
761193008783	NTP binding site [chemical binding]; other site
761193008784	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
761193008785	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
761193008786	active site
761193008787	nucleic acid binding site [nucleotide binding]; other site
761193008788	Acyltransferase family; Region: Acyl_transf_3; pfam01757
761193008789	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
761193008790	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
761193008791	putative binding surface; other site
761193008792	active site
761193008793	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
761193008794	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008795	active site
761193008796	phosphorylation site [posttranslational modification]
761193008797	intermolecular recognition site; other site
761193008798	dimerization interface [polypeptide binding]; other site
761193008799	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193008800	Walker A motif; other site
761193008801	ATP binding site [chemical binding]; other site
761193008802	Walker B motif; other site
761193008803	arginine finger; other site
761193008804	Cupin domain; Region: Cupin_2; pfam07883
761193008805	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193008806	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193008807	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193008808	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193008809	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193008810	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193008811	COGs: COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin; InterPro IPR008775; KEGG: dfe:Dfer_4437 phytanoyl-CoA dioxygenase; PFAM: Phytanoyl-CoA dioxygenase; SPTR: Phytanoyl-CoA dioxygenase
761193008812	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721
761193008813	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193008814	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
761193008815	classical (c) SDRs; Region: SDR_c; cd05233
761193008816	NAD(P) binding site [chemical binding]; other site
761193008817	active site
761193008818	COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262; KEGG: lby:Lbys_2339 L-lactate dehydrogenase (cytochrome); PFAM: FMN-dependent dehydrogenase; PRIAM: L-lactate dehydrogenase (cytochrome); SPTR: L-lactate dehydrogenase (Cytochrome)
761193008819	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
761193008820	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
761193008821	phosphate binding site [ion binding]; other site
761193008822	GntP family permease; Region: GntP_permease; pfam02447
761193008823	fructuronate transporter; Provisional; Region: PRK10034; cl15264
761193008824	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193008825	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193008826	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193008827	DNA binding residues [nucleotide binding]
761193008828	FecR protein; Region: FecR; pfam04773
761193008829	Secretin and TonB N terminus short domain; Region: STN; pfam07660
761193008830	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193008831	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193008832	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193008833	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193008834	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
761193008835	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193008836	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
761193008837	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
761193008838	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
761193008839	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193008840	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193008841	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193008842	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193008843	manually curated
761193008844	InterPro IPR003346; KEGG: sli:Slin_6004 transposase IS116/IS110/IS902 family protein; PFAM: Transposase, IS116/IS110/IS902; SPTR: Transposase IS116/IS110/IS902 family protein
761193008845	Transposase; Region: DEDD_Tnp_IS110; pfam01548
761193008846	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
761193008847	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
761193008848	InterPro IPR001387:IPR017507; KEGG: bvu:BVU_1930  transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR:  uncharacterized protein; TIGRFAM: Transcriptional regulator, HipB-like
761193008849	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193008850	non-specific DNA binding site [nucleotide binding]; other site
761193008851	salt bridge; other site
761193008852	sequence-specific DNA binding site [nucleotide binding]; other site
761193008853	HipA N-terminal domain; Region: couple_hipA; TIGR03071
761193008854	HipA-like N-terminal domain; Region: HipA_N; pfam07805
761193008855	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
761193008856	HipA-like C-terminal domain; Region: HipA_C; pfam07804
761193008857	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
761193008858	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
761193008859	Part of AAA domain; Region: AAA_19; pfam13245
761193008860	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
761193008861	AAA domain; Region: AAA_12; pfam13087
761193008862	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
761193008863	putative active site [active]
761193008864	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
761193008865	PLD-like domain; Region: PLDc_2; pfam13091
761193008866	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
761193008867	putative active site [active]
761193008868	catalytic site [active]
761193008869	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
761193008870	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193008871	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193008872	HsdM N-terminal domain; Region: HsdM_N; pfam12161
761193008873	Methyltransferase domain; Region: Methyltransf_26; pfam13659
761193008874	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
761193008875	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
761193008876	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193008877	ATP binding site [chemical binding]; other site
761193008878	putative Mg++ binding site [ion binding]; other site
761193008879	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193008880	nucleotide binding region [chemical binding]; other site
761193008881	ATP-binding site [chemical binding]; other site
761193008882	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
761193008883	active site
761193008884	catalytic residues [active]
761193008885	DNA binding site [nucleotide binding]
761193008886	Int/Topo IB signature motif; other site
761193008887	Helix-turn-helix domain; Region: HTH_17; pfam12728
761193008888	VRR-NUC domain; Region: VRR_NUC; pfam08774
761193008889	glutathione reductase; Validated; Region: PRK06116
761193008890	Phage terminase, small subunit; Region: Terminase_4; pfam05119
761193008891	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
761193008892	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
761193008893	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
761193008894	Putative collagen-binding domain of a collagenase; Region: Collagen_bind_2; pfam12904
761193008895	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
761193008896	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193008897	FtsX-like permease family; Region: FtsX; pfam02687
761193008898	coenzyme PQQ biosynthesis protein B; Region: PQQ_syn_pqqB; TIGR02108
761193008899	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
761193008900	COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); HAMAP: DNA ligase; InterProIPR013840:IPR001357:IPR013839:IPR004150:IPR 004149:IPR001679; KEGG: dfe:Dfer_5111 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase, adenylation; NAD-dependent DNA ligase, OB-fold; Zinc-finger, NAD-dependent DNA ligase C4-type; BRCT; SMART: NAD-dependent DNA ligase, N-terminal; BRCT; SPTR: DNA ligase, NAD-dependent; TIGRFAM: NAD-dependent DNA ligase
761193008901	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
761193008902	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
761193008903	nucleotide binding pocket [chemical binding]; other site
761193008904	K-X-D-G motif; other site
761193008905	catalytic site [active]
761193008906	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
761193008907	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
761193008908	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193008909	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
761193008910	Dimer interface [polypeptide binding]; other site
761193008911	BRCT sequence motif; other site
761193008912	PIN domain; Region: PIN_2; cl17859
761193008913	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
761193008914	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
761193008915	active site
761193008916	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
761193008917	homodimer interface [polypeptide binding]; other site
761193008918	metal binding site [ion binding]; metal-binding site
761193008919	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
761193008920	nudix motif; other site
761193008921	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193008922	conserved repeat domain; Region: B_ant_repeat; TIGR01451
761193008923	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193008924	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008925	ATP binding site [chemical binding]; other site
761193008926	Mg2+ binding site [ion binding]; other site
761193008927	G-X-G motif; other site
761193008928	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193008929	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008930	active site
761193008931	phosphorylation site [posttranslational modification]
761193008932	intermolecular recognition site; other site
761193008933	dimerization interface [polypeptide binding]; other site
761193008934	LytTr DNA-binding domain; Region: LytTR; smart00850
761193008935	PspC domain; Region: PspC; pfam04024
761193008936	PspC domain; Region: PspC; pfam04024
761193008937	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
761193008938	Predicted transcriptional regulators [Transcription]; Region: COG1695
761193008939	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
761193008940	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
761193008941	hypothetical protein; Provisional; Region: PRK10621
761193008942	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
761193008943	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
761193008944	nudix motif; other site
761193008945	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
761193008946	ribulokinase; Provisional; Region: PRK04123
761193008947	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
761193008948	N- and C-terminal domain interface [polypeptide binding]; other site
761193008949	active site
761193008950	MgATP binding site [chemical binding]; other site
761193008951	catalytic site [active]
761193008952	metal binding site [ion binding]; metal-binding site
761193008953	carbohydrate binding site [chemical binding]; other site
761193008954	homodimer interface [polypeptide binding]; other site
761193008955	L-arabinose isomerase; Provisional; Region: PRK02929
761193008956	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
761193008957	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
761193008958	trimer interface [polypeptide binding]; other site
761193008959	putative substrate binding site [chemical binding]; other site
761193008960	putative metal binding site [ion binding]; other site
761193008961	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
761193008962	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
761193008963	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
761193008964	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
761193008965	intersubunit interface [polypeptide binding]; other site
761193008966	active site
761193008967	Zn2+ binding site [ion binding]; other site
761193008968	Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) and related proteins; solute binding domain; Region: SLC5sbd_vSGLT; cd10325
761193008969	putative transporter; Provisional; Region: PRK10484
761193008970	Na binding site [ion binding]; other site
761193008971	substrate binding site [chemical binding]; other site
761193008972	isocitrate dehydrogenase; Validated; Region: PRK09222
761193008973	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
761193008974	Transcriptional regulator [Transcription]; Region: LysR; COG0583
761193008975	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
761193008976	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
761193008977	dimerization interface [polypeptide binding]; other site
761193008978	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
761193008979	CHASE3 domain; Region: CHASE3; pfam05227
761193008980	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
761193008981	GAF domain; Region: GAF_3; pfam13492
761193008982	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193008983	dimer interface [polypeptide binding]; other site
761193008984	phosphorylation site [posttranslational modification]
761193008985	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193008986	ATP binding site [chemical binding]; other site
761193008987	Mg2+ binding site [ion binding]; other site
761193008988	G-X-G motif; other site
761193008989	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008990	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008991	active site
761193008992	phosphorylation site [posttranslational modification]
761193008993	intermolecular recognition site; other site
761193008994	dimerization interface [polypeptide binding]; other site
761193008995	Response regulator receiver domain; Region: Response_reg; pfam00072
761193008996	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193008997	active site
761193008998	phosphorylation site [posttranslational modification]
761193008999	intermolecular recognition site; other site
761193009000	dimerization interface [polypeptide binding]; other site
761193009001	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
761193009002	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
761193009003	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
761193009004	CheB methylesterase; Region: CheB_methylest; pfam01339
761193009005	Response regulator receiver domain; Region: Response_reg; pfam00072
761193009006	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193009007	active site
761193009008	phosphorylation site [posttranslational modification]
761193009009	intermolecular recognition site; other site
761193009010	dimerization interface [polypeptide binding]; other site
761193009011	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193009012	dimer interface [polypeptide binding]; other site
761193009013	phosphorylation site [posttranslational modification]
761193009014	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193009015	ATP binding site [chemical binding]; other site
761193009016	Mg2+ binding site [ion binding]; other site
761193009017	G-X-G motif; other site
761193009018	Response regulator receiver domain; Region: Response_reg; pfam00072
761193009019	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193009020	active site
761193009021	phosphorylation site [posttranslational modification]
761193009022	intermolecular recognition site; other site
761193009023	dimerization interface [polypeptide binding]; other site
761193009024	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193009025	Bacterial sugar transferase; Region: Bac_transf; pfam02397
761193009026	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
761193009027	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
761193009028	Probable Catalytic site; other site
761193009029	metal-binding site
761193009030	poly-beta-1,6 N-acetyl-D-glucosamine synthase; Region: PgaC_IcaA; TIGR03937
761193009031	CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; Region: CESA_like_1; cd06439
761193009032	DXD motif; other site
761193009033	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
761193009034	Core-2/I-Branching enzyme; Region: Branch; pfam02485
761193009035	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
761193009036	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
761193009037	trimer interface [polypeptide binding]; other site
761193009038	active site
761193009039	substrate binding site [chemical binding]; other site
761193009040	CoA binding site [chemical binding]; other site
761193009041	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: GT1_like_1; cd04950
761193009042	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193009043	putative homodimer interface [polypeptide binding]; other site
761193009044	Outer membrane efflux protein; Region: OEP; pfam02321
761193009045	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
761193009046	colanic acid exporter; Provisional; Region: PRK10459
761193009047	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
761193009048	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
761193009049	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193009050	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
761193009051	active site
761193009052	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193009053	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193009054	active site
761193009055	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193009056	active site
761193009057	Carbohydrate Binding Module 6 (CBM6); appended to glycoside hydrolase (GH) domains, including GH5 (cellulase); Region: CBM6_cellulase-like; cd04080
761193009058	Ca binding site [ion binding]; other site
761193009059	ligand binding site I [chemical binding]; other site
761193009060	homodimer interface [polypeptide binding]; other site
761193009061	ligand binding site II [chemical binding]; other site
761193009062	Carbohydrate Binding Module 6 (CBM6); appended to glycoside hydrolase (GH) domains, including GH5 (cellulase); Region: CBM6_cellulase-like; cd04080
761193009063	Ca binding site [ion binding]; other site
761193009064	ligand binding site I [chemical binding]; other site
761193009065	homodimer interface [polypeptide binding]; other site
761193009066	ligand binding site II [chemical binding]; other site
761193009067	Carbohydrate Binding Module 6 (CBM6); appended to glycoside hydrolase (GH) domains, including GH5 (cellulase); Region: CBM6_cellulase-like; cd04080
761193009068	Ca binding site [ion binding]; other site
761193009069	ligand binding site I [chemical binding]; other site
761193009070	homodimer interface [polypeptide binding]; other site
761193009071	ligand binding site II [chemical binding]; other site
761193009072	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
761193009073	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
761193009074	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193009075	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
761193009076	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
761193009077	DXD motif; other site
761193009078	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
761193009079	Outer membrane efflux protein; Region: OEP; pfam02321
761193009080	Outer membrane efflux protein; Region: OEP; pfam02321
761193009081	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193009082	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193009083	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193009084	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
761193009085	EamA-like transporter family; Region: EamA; pfam00892
761193009086	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
761193009087	EamA-like transporter family; Region: EamA; pfam00892
761193009088	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
761193009089	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cl01298
761193009090	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
761193009091	Zn binding site [ion binding]; other site
761193009092	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193009093	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193009094	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
761193009095	Histidine kinase; Region: HisKA_3; pfam07730
761193009096	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193009097	ATP binding site [chemical binding]; other site
761193009098	Mg2+ binding site [ion binding]; other site
761193009099	G-X-G motif; other site
761193009100	type 2 lantibiotic biosynthesis protein LanM; Region: lanti_2_LanM; TIGR03897
761193009101	Phosphotransferase enzyme family; Region: APH; pfam01636
761193009102	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
761193009103	ATP binding site [chemical binding]; other site
761193009104	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
761193009105	active site
761193009106	ATP binding site [chemical binding]; other site
761193009107	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12901
761193009108	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
761193009109	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
761193009110	nucleotide binding region [chemical binding]; other site
761193009111	ATP-binding site [chemical binding]; other site
761193009112	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193009113	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
761193009114	M28 Zn-Peptidase Aeromonas (Vibrio) proteolytica aminopeptidase (AAP)-like; Region: M28_AAP_like; cd05642
761193009115	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193009116	putative metal binding site [ion binding]; other site
761193009117	Domain of unknown function (DUF3472); Region: DUF3472; pfam11958
761193009118	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
761193009119	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193009120	catalytic loop [active]
761193009121	iron binding site [ion binding]; other site
761193009122	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
761193009123	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
761193009124	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
761193009125	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
761193009126	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
761193009127	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
761193009128	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
761193009129	endonuclease III; Region: ENDO3c; smart00478
761193009130	minor groove reading motif; other site
761193009131	helix-hairpin-helix signature motif; other site
761193009132	substrate binding pocket [chemical binding]; other site
761193009133	active site
761193009134	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
761193009135	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193009136	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
761193009137	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
761193009138	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193009139	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
761193009140	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193009141	catalytic loop [active]
761193009142	iron binding site [ion binding]; other site
761193009143	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
761193009144	homotrimer interaction site [polypeptide binding]; other site
761193009145	putative active site [active]
761193009146	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
761193009147	catalytic residues [active]
761193009148	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
761193009149	MraW methylase family; Region: Methyltransf_5; cl17771
761193009150	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
761193009151	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
761193009152	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
761193009153	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
761193009154	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193009155	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
761193009156	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193009157	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193009158	active site
761193009159	phosphorylation site [posttranslational modification]
761193009160	intermolecular recognition site; other site
761193009161	dimerization interface [polypeptide binding]; other site
761193009162	LytTr DNA-binding domain; Region: LytTR; smart00850
761193009163	Histidine kinase; Region: His_kinase; pfam06580
761193009164	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
761193009165	heme-binding site [chemical binding]; other site
761193009166	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
761193009167	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
761193009168	Histidine kinase; Region: His_kinase; pfam06580
761193009169	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Deinococcus radiodurans DR2231 protein and its bacterial homologs; Region: NTP-PPase_DR2231_like; cd11530
761193009170	metal binding site [ion binding]; metal-binding site
761193009171	DinB superfamily; Region: DinB_2; pfam12867
761193009172	COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR004866:IPR015882:IPR015883:IPR004867; KEGG: cpi:Cpin_1487 beta-N-acetylhexosaminidase; PFAM: Glycoside hydrolase, family 20, catalytic core; Carbohydrate-binding, chitobiase/hexosaminidase-type, N-terminal; Beta-N-acetylhexosaminidase-like; Glycoside hydrolase, family 20, C-terminal; PRIAM: Beta-N-acetylhexosaminidase; SPTR: Beta-N-acetylhexosaminidase
761193009173	Putative carbohydrate binding domain; Region: CHB_HEX; cl03918
761193009174	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
761193009175	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
761193009176	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
761193009177	active site
761193009178	C-terminal Early set domain associated with the catalytic domain of chitobiase (also called N-acetylglucosaminidase); Region: E_set_Chitobiase_C; cd02847
761193009179	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
761193009180	KEGG: npu:Npun_F6102 hypothetical protein; SPTR:  uncharacterized protein
761193009181	Microscilla MS158 and related proteins, metallophosphatase domain; Region: MPP_MS158; cd07404
761193009182	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193009183	putative active site [active]
761193009184	putative metal binding site [ion binding]; other site
761193009185	Amino acid permease; Region: AA_permease_2; pfam13520
761193009186	DinB superfamily; Region: DinB_2; pfam12867
761193009187	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
761193009188	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
761193009189	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
761193009190	active site
761193009191	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
761193009192	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
761193009193	NADP binding site [chemical binding]; other site
761193009194	homopentamer interface [polypeptide binding]; other site
761193009195	substrate binding site [chemical binding]; other site
761193009196	active site
761193009197	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
761193009198	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
761193009199	DNA binding residues [nucleotide binding]
761193009200	B12 binding domain; Region: B12-binding_2; pfam02607
761193009201	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
761193009202	Protein of unknown function (DUF422); Region: DUF422; cl00991
761193009203	Yqey-like protein; Region: YqeY; pfam09424
761193009204	Colicin V production protein; Region: Colicin_V; pfam02674
761193009205	Rossmann-like domain; Region: Rossmann-like; pfam10727
761193009206	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
761193009207	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193009208	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193009209	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193009210	DNA binding residues [nucleotide binding]
761193009211	ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682
761193009212	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
761193009213	putative Cl- selectivity filter; other site
761193009214	putative pore gating glutamate residue; other site
761193009215	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193009216	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193009217	Protein of unknown function (DUF456); Region: DUF456; pfam04306
761193009218	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
761193009219	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
761193009220	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193009221	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
761193009222	Walker A/P-loop; other site
761193009223	ATP binding site [chemical binding]; other site
761193009224	Q-loop/lid; other site
761193009225	ABC transporter signature motif; other site
761193009226	Walker B; other site
761193009227	D-loop; other site
761193009228	H-loop/switch region; other site
761193009229	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
761193009230	active site
761193009231	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
761193009232	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
761193009233	Ligand Binding Site [chemical binding]; other site
761193009234	Molecular Tunnel; other site
761193009235	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
761193009236	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; cl05126
761193009237	Transglutaminase-like superfamily; Region: Transglut_core3; pfam13471
761193009238	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
761193009239	active site
761193009240	metal-binding site [ion binding]
761193009241	nucleotide-binding site [chemical binding]; other site
761193009242	GSCFA family; Region: GSCFA; pfam08885
761193009243	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193009244	active site
761193009245	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
761193009246	putative rRNA binding site [nucleotide binding]; other site
761193009247	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
761193009248	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193009249	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193009250	Fatty acid desaturase; Region: FA_desaturase; pfam00487
761193009251	The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615
761193009252	putative di-iron ligands [ion binding]; other site
761193009253	HsdM N-terminal domain; Region: HsdM_N; pfam12161
761193009254	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
761193009255	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193009256	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
761193009257	Homeodomain-like domain; Region: HTH_23; pfam13384
761193009258	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193009259	Homeodomain-like domain; Region: HTH_32; pfam13565
761193009260	Winged helix-turn helix; Region: HTH_33; pfam13592
761193009261	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193009262	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193009263	Prodigal; manually curated
761193009264	SPTR:  uncharacterized protein
761193009265	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193009266	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193009267	non-specific DNA binding site [nucleotide binding]; other site
761193009268	salt bridge; other site
761193009269	sequence-specific DNA binding site [nucleotide binding]; other site
761193009270	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
761193009271	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
761193009272	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193009273	ATP binding site [chemical binding]; other site
761193009274	putative Mg++ binding site [ion binding]; other site
761193009275	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
761193009276	Thiamine pyrophosphokinase; Region: TPK; cd07995
761193009277	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
761193009278	active site
761193009279	dimerization interface [polypeptide binding]; other site
761193009280	thiamine binding site [chemical binding]; other site
761193009281	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193009282	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
761193009283	active site
761193009284	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
761193009285	CoA binding domain; Region: CoA_binding; smart00881
761193009286	CoA-ligase; Region: Ligase_CoA; pfam00549
761193009287	Domain of unknown function (DUF4271); Region: DUF4271; pfam14093
761193009288	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
761193009289	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
761193009290	active site
761193009291	Bacteroidetes-specific putative membrane protein; Region: Bac_Flav_fam_1; TIGR03519
761193009292	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
761193009293	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
761193009294	gliding motility-associated protein GldM; Region: GldM_gliding; TIGR03517
761193009295	GldM N-terminal domain; Region: GldM_N; pfam12081
761193009296	GldM C-terminal domain; Region: GldM_C; pfam12080
761193009297	gliding motility associated protien GldN; Region: GldN; TIGR03523
761193009298	gliding motility associated protien GldN; Region: GldN; TIGR03523
761193009299	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
761193009300	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193009301	active site
761193009302	hypothetical protein; Reviewed; Region: PRK00024
761193009303	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
761193009304	MPN+ (JAMM) motif; other site
761193009305	Zinc-binding site [ion binding]; other site
761193009306	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
761193009307	Protein of unknown function (DUF1572); Region: DUF1572; pfam07609
761193009308	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
761193009309	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193009310	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
761193009311	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193009312	SPTR:  uncharacterized protein
761193009313	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193009314	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193009315	active site
761193009316	phosphorylation site [posttranslational modification]
761193009317	intermolecular recognition site; other site
761193009318	dimerization interface [polypeptide binding]; other site
761193009319	LytTr DNA-binding domain; Region: LytTR; smart00850
761193009320	Histidine kinase; Region: His_kinase; pfam06580
761193009321	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
761193009322	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; cl02930
761193009323	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
761193009324	Soluble P-type ATPase [General function prediction only]; Region: COG4087
761193009325	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
761193009326	Penicillin amidase; Region: Penicil_amidase; pfam01804
761193009327	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193009328	active site
761193009329	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193009330	active site
761193009331	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193009332	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
761193009333	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193009334	Uncharacterized conserved protein [Function unknown]; Region: COG3268
761193009335	NAD(P) binding site [chemical binding]; other site
761193009336	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193009337	active site residue [active]
761193009338	Protein of unknown function (DUF3365); Region: DUF3365; pfam11845
761193009339	Low molecular weight phosphatase family; Region: LMWPc; cl00105
761193009340	active site
761193009341	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
761193009342	arsenical-resistance protein; Region: acr3; TIGR00832
761193009343	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193009344	dimerization interface [polypeptide binding]; other site
761193009345	putative DNA binding site [nucleotide binding]; other site
761193009346	putative Zn2+ binding site [ion binding]; other site
761193009347	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
761193009348	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
761193009349	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193009350	catalytic residues [active]
761193009351	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193009352	active site residue [active]
761193009353	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193009354	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
761193009355	dimerization interface [polypeptide binding]; other site
761193009356	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193009357	dimer interface [polypeptide binding]; other site
761193009358	phosphorylation site [posttranslational modification]
761193009359	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193009360	ATP binding site [chemical binding]; other site
761193009361	Mg2+ binding site [ion binding]; other site
761193009362	G-X-G motif; other site
761193009363	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193009364	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193009365	active site
761193009366	phosphorylation site [posttranslational modification]
761193009367	intermolecular recognition site; other site
761193009368	dimerization interface [polypeptide binding]; other site
761193009369	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193009370	DNA binding site [nucleotide binding]
761193009371	Outer membrane efflux protein; Region: OEP; pfam02321
761193009372	Outer membrane efflux protein; Region: OEP; pfam02321
761193009373	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193009374	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193009375	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193009376	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
761193009377	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193009378	TPR motif; other site
761193009379	binding surface
761193009380	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193009381	TPR motif; other site
761193009382	binding surface
761193009383	TPR/MLP1/MLP2-like protein; Region: TPR_MLP1_2; pfam07926
761193009384	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193009385	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
761193009386	dimerization interface [polypeptide binding]; other site
761193009387	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193009388	dimer interface [polypeptide binding]; other site
761193009389	phosphorylation site [posttranslational modification]
761193009390	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193009391	ATP binding site [chemical binding]; other site
761193009392	Mg2+ binding site [ion binding]; other site
761193009393	G-X-G motif; other site
761193009394	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193009395	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193009396	active site
761193009397	phosphorylation site [posttranslational modification]
761193009398	intermolecular recognition site; other site
761193009399	dimerization interface [polypeptide binding]; other site
761193009400	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193009401	DNA binding site [nucleotide binding]
761193009402	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
761193009403	Ligand Binding Site [chemical binding]; other site
761193009404	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
761193009405	Ligand Binding Site [chemical binding]; other site
761193009406	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193009407	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193009408	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193009409	recombination protein RecR; Reviewed; Region: recR; PRK00076
761193009410	RecR protein; Region: RecR; pfam02132
761193009411	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
761193009412	putative active site [active]
761193009413	putative metal-binding site [ion binding]; other site
761193009414	tetramer interface [polypeptide binding]; other site
761193009415	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193009416	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193009417	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193009418	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193009419	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193009420	SusD family; Region: SusD; pfam07980
761193009421	GTPase RsgA; Reviewed; Region: PRK00098
761193009422	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
761193009423	RNA binding site [nucleotide binding]; other site
761193009424	homodimer interface [polypeptide binding]; other site
761193009425	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
761193009426	GTPase/Zn-binding domain interface [polypeptide binding]; other site
761193009427	GTP/Mg2+ binding site [chemical binding]; other site
761193009428	G4 box; other site
761193009429	G5 box; other site
761193009430	G1 box; other site
761193009431	Switch I region; other site
761193009432	G2 box; other site
761193009433	G3 box; other site
761193009434	Switch II region; other site
761193009435	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
761193009436	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
761193009437	active site
761193009438	NAD binding site [chemical binding]; other site
761193009439	metal binding site [ion binding]; metal-binding site
761193009440	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
761193009441	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
761193009442	inhibitor-cofactor binding pocket; inhibition site
761193009443	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193009444	catalytic residue [active]
761193009445	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
761193009446	active site
761193009447	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193009448	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193009449	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
761193009450	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; cl17322
761193009451	Outer membrane efflux protein; Region: OEP; pfam02321
761193009452	FeoA domain; Region: FeoA; pfam04023
761193009453	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
761193009454	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
761193009455	G1 box; other site
761193009456	GTP/Mg2+ binding site [chemical binding]; other site
761193009457	Switch I region; other site
761193009458	G2 box; other site
761193009459	G3 box; other site
761193009460	Switch II region; other site
761193009461	G4 box; other site
761193009462	G5 box; other site
761193009463	Nucleoside recognition; Region: Gate; pfam07670
761193009464	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
761193009465	Nucleoside recognition; Region: Gate; pfam07670
761193009466	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
761193009467	Histone deacetylase class IV also known as histone deacetylase 11; Region: HDAC_classIV; cd09993
761193009468	putative active site [active]
761193009469	Zn binding site [ion binding]; other site
761193009470	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
761193009471	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
761193009472	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
761193009473	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
761193009474	active site
761193009475	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193009476	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
761193009477	Predicted NAD/FAD-dependent oxidoreductase [General function prediction only]; Region: COG3380
761193009478	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193009479	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
761193009480	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
761193009481	GDP-binding site [chemical binding]; other site
761193009482	ACT binding site; other site
761193009483	IMP binding site; other site
761193009484	ferric uptake regulator; Provisional; Region: fur; PRK09462
761193009485	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
761193009486	metal binding site 2 [ion binding]; metal-binding site
761193009487	putative DNA binding helix; other site
761193009488	metal binding site 1 [ion binding]; metal-binding site
761193009489	dimer interface [polypeptide binding]; other site
761193009490	structural Zn2+ binding site [ion binding]; other site
761193009491	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
761193009492	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
761193009493	Zn2+ binding site [ion binding]; other site
761193009494	Mg2+ binding site [ion binding]; other site
761193009495	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
761193009496	synthetase active site [active]
761193009497	NTP binding site [chemical binding]; other site
761193009498	metal binding site [ion binding]; metal-binding site
761193009499	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
761193009500	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
761193009501	trigger factor; Region: tig; TIGR00115
761193009502	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
761193009503	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193009504	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193009505	ligand binding site [chemical binding]; other site
761193009506	flexible hinge region; other site
761193009507	COGs: COG4122 O-methyltransferase; InterPro IPR013216; KEGG: scl:sce1553 O-methyltransferase; PFAM: Methyltransferase type 11; SPTR: O-methyltransferase
761193009508	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193009509	S-adenosylmethionine binding site [chemical binding]; other site
761193009510	Putative esterase; Region: Esterase; pfam00756
761193009511	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4947
761193009512	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
761193009513	Class III alcohol dehydrogenase; Region: Zn_ADH_class_III; cd08279
761193009514	NAD binding site [chemical binding]; other site
761193009515	catalytic Zn binding site [ion binding]; other site
761193009516	substrate binding site [chemical binding]; other site
761193009517	structural Zn binding site [ion binding]; other site
761193009518	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
761193009519	Ligand Binding Site [chemical binding]; other site
761193009520	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
761193009521	Ligand Binding Site [chemical binding]; other site
761193009522	InterPro IPR008756; KEGG: sli:Slin_5967 peptidase M56 BlaR1; PFAM: Peptidase M56, BlaR1; SPTR: Peptidase M56 BlaR1
761193009523	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
761193009524	Penicillinase repressor; Region: Pencillinase_R; pfam03965
761193009525	Dienelactone hydrolase family; Region: DLH; pfam01738
761193009526	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193009527	FeS assembly ATPase SufC; Region: sufC; TIGR01978
761193009528	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
761193009529	Walker A/P-loop; other site
761193009530	ATP binding site [chemical binding]; other site
761193009531	Q-loop/lid; other site
761193009532	ABC transporter signature motif; other site
761193009533	Walker B; other site
761193009534	D-loop; other site
761193009535	H-loop/switch region; other site
761193009536	FeS assembly protein SufD; Region: sufD; TIGR01981
761193009537	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
761193009538	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
761193009539	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
761193009540	putative ligand binding site [chemical binding]; other site
761193009541	putative NAD binding site [chemical binding]; other site
761193009542	catalytic site [active]
761193009543	maltose phosphorylase; Provisional; Region: PRK13807
761193009544	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
761193009545	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
761193009546	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
761193009547	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
761193009548	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
761193009549	active site
761193009550	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
761193009551	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
761193009552	substrate binding pocket [chemical binding]; other site
761193009553	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193009554	Predicted proline hydroxylase [Posttranslational modification, protein turnover, chaperones]; Region: EGL-9; COG3751
761193009555	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
761193009556	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
761193009557	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
761193009558	Coenzyme A binding pocket [chemical binding]; other site
761193009559	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
761193009560	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
761193009561	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
761193009562	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
761193009563	DsrE/DsrF-like family; Region: DrsE; pfam02635
761193009564	COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: sli:Slin_6089 DNA polymerase III gamma/tau subunits-like protein; SPTR: DNA polymerase III gamma/tau subunits-like protein
761193009565	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
761193009566	DNA polymerase III subunit delta'; Validated; Region: PRK08485
761193009567	Family description; Region: VCBS; pfam13517
761193009568	Family description; Region: VCBS; pfam13517
761193009569	Family description; Region: VCBS; pfam13517
761193009570	Family description; Region: VCBS; pfam13517
761193009571	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
761193009572	Family description; Region: VCBS; pfam13517
761193009573	Family description; Region: VCBS; pfam13517
761193009574	Family description; Region: VCBS; pfam13517
761193009575	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193009576	SusD family; Region: SusD; pfam07980
761193009577	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193009578	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193009579	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193009580	Putative ATP-dependant zinc protease; Region: Zn_protease; cl01682
761193009581	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
761193009582	ATP-grasp domain; Region: ATP-grasp_4; cl17255
761193009583	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
761193009584	nudix motif; other site
761193009585	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
761193009586	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193009587	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193009588	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193009589	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193009590	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
761193009591	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193009592	Family description; Region: VCBS; pfam13517
761193009593	Family description; Region: VCBS; pfam13517
761193009594	Family description; Region: VCBS; pfam13517
761193009595	Family description; Region: VCBS; pfam13517
761193009596	Family description; Region: VCBS; pfam13517
761193009597	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
761193009598	Family description; Region: VCBS; pfam13517
761193009599	Family description; Region: VCBS; pfam13517
761193009600	Family description; Region: VCBS; pfam13517
761193009601	Family description; Region: VCBS; pfam13517
761193009602	Cupin domain; Region: Cupin_2; pfam07883
761193009603	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193009604	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193009605	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
761193009606	Metal-binding active site; metal-binding site
761193009607	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193009608	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
761193009609	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
761193009610	Putative collagen-binding domain of a collagenase; Region: Collagen_bind_2; pfam12904
761193009611	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
761193009612	Putative collagen-binding domain of a collagenase; Region: Collagen_bind_2; pfam12904
761193009613	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193009614	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193009615	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193009616	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
761193009617	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
761193009618	Walker A/P-loop; other site
761193009619	ATP binding site [chemical binding]; other site
761193009620	Q-loop/lid; other site
761193009621	ABC transporter signature motif; other site
761193009622	Walker B; other site
761193009623	D-loop; other site
761193009624	H-loop/switch region; other site
761193009625	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
761193009626	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
761193009627	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
761193009628	TM-ABC transporter signature motif; other site
761193009629	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
761193009630	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
761193009631	ligand binding site [chemical binding]; other site
761193009632	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
761193009633	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u1; cd11477
761193009634	Na binding site [ion binding]; other site
761193009635	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
761193009636	active site
761193009637	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193009638	putative active site [active]
761193009639	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
761193009640	dimerization interface [polypeptide binding]; other site
761193009641	putative active cleft [active]
761193009642	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
761193009643	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193009644	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
761193009645	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193009646	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
761193009647	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
761193009648	active site
761193009649	catalytic tetrad [active]
761193009650	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
761193009651	Mechanosensitive ion channel; Region: MS_channel; pfam00924
761193009652	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
761193009653	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
761193009654	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193009655	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
761193009656	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
761193009657	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193009658	catalytic triad [active]
761193009659	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
761193009660	four helix bundle protein; Region: TIGR02436
761193009661	transketolase; Reviewed; Region: PRK05899
761193009662	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
761193009663	TPP-binding site [chemical binding]; other site
761193009664	dimer interface [polypeptide binding]; other site
761193009665	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193009666	putative active site [active]
761193009667	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193009668	AAA domain; Region: AAA_21; pfam13304
761193009669	Walker A/P-loop; other site
761193009670	ATP binding site [chemical binding]; other site
761193009671	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193009672	ABC transporter signature motif; other site
761193009673	Walker B; other site
761193009674	D-loop; other site
761193009675	H-loop/switch region; other site
761193009676	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
761193009677	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
761193009678	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
761193009679	PYR/PP interface [polypeptide binding]; other site
761193009680	dimer interface [polypeptide binding]; other site
761193009681	TPP binding site [chemical binding]; other site
761193009682	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
761193009683	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
761193009684	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193009685	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193009686	DNA binding residues [nucleotide binding]
761193009687	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
761193009688	LytTr DNA-binding domain; Region: LytTR; smart00850
761193009689	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
761193009690	active site
761193009691	catalytic site [active]
761193009692	substrate binding site [chemical binding]; other site
761193009693	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193009694	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193009695	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
761193009696	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
761193009697	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
761193009698	antiporter inner membrane protein; Provisional; Region: PRK11670
761193009699	Domain of unknown function DUF59; Region: DUF59; pfam01883
761193009700	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
761193009701	Walker A motif; other site
761193009702	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193009703	D-galactonate transporter; Region: 2A0114; TIGR00893
761193009704	putative substrate translocation pore; other site
761193009705	Histidine kinase; Region: His_kinase; pfam06580
761193009706	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193009707	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193009708	active site
761193009709	phosphorylation site [posttranslational modification]
761193009710	intermolecular recognition site; other site
761193009711	dimerization interface [polypeptide binding]; other site
761193009712	LytTr DNA-binding domain; Region: LytTR; smart00850
761193009713	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
761193009714	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193009715	active site residue [active]
761193009716	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193009717	active site residue [active]
761193009718	Penicillinase repressor; Region: Pencillinase_R; pfam03965
761193009719	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
761193009720	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA; cl01007
761193009721	leucyl-tRNA synthetase, eubacterial and mitochondrial family; Region: leuS_bact; TIGR00396
761193009722	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193009723	active site
761193009724	HIGH motif; other site
761193009725	nucleotide binding site [chemical binding]; other site
761193009726	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193009727	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
761193009728	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193009729	active site
761193009730	KMSKS motif; other site
761193009731	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193009732	active site
761193009733	KMSKS motif; other site
761193009734	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
761193009735	tRNA binding surface [nucleotide binding]; other site
761193009736	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193009737	putative active site [active]
761193009738	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
761193009739	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
761193009740	Ligand binding site; other site
761193009741	oligomer interface; other site
761193009742	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
761193009743	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
761193009744	oligomer interface [polypeptide binding]; other site
761193009745	metal binding site [ion binding]; metal-binding site
761193009746	metal binding site [ion binding]; metal-binding site
761193009747	Cl binding site [ion binding]; other site
761193009748	aspartate ring; other site
761193009749	basic sphincter; other site
761193009750	putative hydrophobic gate; other site
761193009751	periplasmic entrance; other site
761193009752	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193009753	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
761193009754	active site
761193009755	motif I; other site
761193009756	motif II; other site
761193009757	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
761193009758	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
761193009759	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Region: LPLAT_AAK14816-like; cd07992
761193009760	putative acyl-acceptor binding pocket; other site
761193009761	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193009762	putative active site [active]
761193009763	short chain dehydrogenase; Validated; Region: PRK06182
761193009764	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
761193009765	NADP binding site [chemical binding]; other site
761193009766	active site
761193009767	steroid binding site; other site
761193009768	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193009769	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193009770	Uncharacterized subgroup of the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domain family; Region: START_1; cd08876
761193009771	putative lipid binding site [chemical binding]; other site
761193009772	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
761193009773	Active site serine [active]
761193009774	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
761193009775	Sugar-binding cellulase-like; Region: Cellulase-like; pfam12876
761193009776	DinB superfamily; Region: DinB_2; pfam12867
761193009777	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193009778	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193009779	active site
761193009780	phosphorylation site [posttranslational modification]
761193009781	intermolecular recognition site; other site
761193009782	dimerization interface [polypeptide binding]; other site
761193009783	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193009784	DNA binding site [nucleotide binding]
761193009785	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
761193009786	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
761193009787	dimerization interface [polypeptide binding]; other site
761193009788	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193009789	dimer interface [polypeptide binding]; other site
761193009790	phosphorylation site [posttranslational modification]
761193009791	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193009792	ATP binding site [chemical binding]; other site
761193009793	Mg2+ binding site [ion binding]; other site
761193009794	G-X-G motif; other site
761193009795	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
761193009796	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
761193009797	tellurium resistance terB-like protein; Region: terB_like; cd07177
761193009798	metal binding site [ion binding]; metal-binding site
761193009799	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
761193009800	Leucine rich repeat; Region: LRR_8; pfam13855
761193009801	Leucine rich repeat; Region: LRR_8; pfam13855
761193009802	hypothetical protein; Provisional; Region: PRK08317
761193009803	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193009804	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
761193009805	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
761193009806	dimer interface [polypeptide binding]; other site
761193009807	motif 1; other site
761193009808	active site
761193009809	motif 2; other site
761193009810	motif 3; other site
761193009811	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
761193009812	anticodon binding site; other site
761193009813	membrane protein insertase; Provisional; Region: PRK01318
761193009814	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
761193009815	Rho termination factor, N-terminal domain; Region: Rho_N; cl06505
761193009816	transcription termination factor Rho; Provisional; Region: PRK12608
761193009817	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
761193009818	RNA binding site [nucleotide binding]; other site
761193009819	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
761193009820	multimer interface [polypeptide binding]; other site
761193009821	Walker A motif; other site
761193009822	ATP binding site [chemical binding]; other site
761193009823	Walker B motif; other site
761193009824	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
761193009825	putative SAM binding site [chemical binding]; other site
761193009826	homodimer interface [polypeptide binding]; other site
761193009827	acyl-CoA esterase; Provisional; Region: PRK10673
761193009828	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
761193009829	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
761193009830	ATP-grasp domain; Region: ATP-grasp; pfam02222
761193009831	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
761193009832	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193009833	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
761193009834	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
761193009835	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_1; cd03400
761193009836	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193009837	putative active site [active]
761193009838	quinolinate synthetase; Provisional; Region: PRK09375
761193009839	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193009840	active site
761193009841	Haemolytic domain; Region: Haemolytic; pfam01809
761193009842	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4185
761193009843	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
761193009844	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
761193009845	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
761193009846	substrate binding site [chemical binding]; other site
761193009847	oxyanion hole (OAH) forming residues; other site
761193009848	trimer interface [polypeptide binding]; other site
761193009849	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
761193009850	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
761193009851	PcfJ-like protein; Region: PcfJ; pfam14284
761193009852	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
761193009853	hypothetical protein; Reviewed; Region: PRK09588
761193009854	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
761193009855	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193009856	active site
761193009857	HIGH motif; other site
761193009858	nucleotide binding site [chemical binding]; other site
761193009859	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
761193009860	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
761193009861	active site
761193009862	KMSKS motif; other site
761193009863	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
761193009864	tRNA binding surface [nucleotide binding]; other site
761193009865	anticodon binding site; other site
761193009866	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
761193009867	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
761193009868	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193009869	putative DNA binding site [nucleotide binding]; other site
761193009870	putative Zn2+ binding site [ion binding]; other site
761193009871	AsnC family; Region: AsnC_trans_reg; pfam01037
761193009872	histidinol-phosphate phosphatase family domain; Region: Histidinol-ppas; TIGR01656
761193009873	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193009874	active site
761193009875	motif I; other site
761193009876	motif II; other site
761193009877	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
761193009878	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
761193009879	dimer interface [polypeptide binding]; other site
761193009880	active site
761193009881	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
761193009882	catalytic residues [active]
761193009883	substrate binding site [chemical binding]; other site
761193009884	glycerol kinase; Provisional; Region: glpK; PRK00047
761193009885	Cellulomonas sp. glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_CsGK_like; cd07789
761193009886	N- and C-terminal domain interface [polypeptide binding]; other site
761193009887	active site
761193009888	MgATP binding site [chemical binding]; other site
761193009889	catalytic site [active]
761193009890	metal binding site [ion binding]; metal-binding site
761193009891	putative homotetramer interface [polypeptide binding]; other site
761193009892	glycerol binding site [chemical binding]; other site
761193009893	homodimer interface [polypeptide binding]; other site
761193009894	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
761193009895	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
761193009896	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
761193009897	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
761193009898	von Willebrand factor type A domain; Region: VWA_2; pfam13519
761193009899	metal ion-dependent adhesion site (MIDAS); other site
761193009900	ethanolamine permease; Region: 2A0305; TIGR00908
761193009901	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
761193009902	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
761193009903	active site
761193009904	Int/Topo IB signature motif; other site
761193009905	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
761193009906	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
761193009907	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193009908	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193009909	catalytic residue [active]
761193009910	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
761193009911	catalytic core [active]
761193009912	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
761193009913	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
761193009914	G1 box; other site
761193009915	putative GEF interaction site [polypeptide binding]; other site
761193009916	GTP/Mg2+ binding site [chemical binding]; other site
761193009917	Switch I region; other site
761193009918	G2 box; other site
761193009919	G3 box; other site
761193009920	Switch II region; other site
761193009921	G4 box; other site
761193009922	G5 box; other site
761193009923	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
761193009924	beta-phosphoglucomutase; Region: bPGM; TIGR01990
761193009925	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193009926	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
761193009927	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193009928	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
761193009929	Haloacid dehalogenase-like hydrolase; Region: Hydrolase_6; pfam13344
761193009930	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193009931	motif II; other site
761193009932	UDP-N-acetylmuramate-alanine ligase [Cell envelope biogenesis, outer membrane]; Region: MurC; COG0773
761193009933	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
761193009934	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
761193009935	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
761193009936	Glycoprotease family; Region: Peptidase_M22; pfam00814
761193009937	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
761193009938	Trp docking motif [polypeptide binding]; other site
761193009939	active site
761193009940	PQQ-like domain; Region: PQQ_2; pfam13360
761193009941	PQQ enzyme repeat; Region: PQQ; pfam01011
761193009942	Winged helix-turn helix; Region: HTH_29; pfam13551
761193009943	Winged helix-turn helix; Region: HTH_33; pfam13592
761193009944	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193009945	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193009946	ligand binding site [chemical binding]; other site
761193009947	flexible hinge region; other site
761193009948	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
761193009949	putative switch regulator; other site
761193009950	non-specific DNA interactions [nucleotide binding]; other site
761193009951	DNA binding site [nucleotide binding]
761193009952	sequence specific DNA binding site [nucleotide binding]; other site
761193009953	putative cAMP binding site [chemical binding]; other site
761193009954	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193009955	NmrA-like family; Region: NmrA; pfam05368
761193009956	NAD(P) binding site [chemical binding]; other site
761193009957	active site
761193009958	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
761193009959	active site
761193009960	metal binding site [ion binding]; metal-binding site
761193009961	Predicted membrane protein [Function unknown]; Region: COG2323
761193009962	Integral membrane protein TerC family; Region: TerC; cl10468
761193009963	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
761193009964	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
761193009965	AAA domain; Region: AAA_30; pfam13604
761193009966	Family description; Region: UvrD_C_2; pfam13538
761193009967	FOG: CBS domain [General function prediction only]; Region: COG0517
761193009968	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_10; cd04623
761193009969	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
761193009970	nudix motif; other site
761193009971	Protein of unknown function (DUF3822); Region: DUF3822; pfam12864
761193009972	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
761193009973	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
761193009974	active site
761193009975	(T/H)XGH motif; other site
761193009976	Protein of unknown function (DUF983); Region: DUF983; cl02211
761193009977	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
761193009978	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
761193009979	Histidine kinase; Region: His_kinase; pfam06580
761193009980	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
761193009981	ATP binding site [chemical binding]; other site
761193009982	Mg2+ binding site [ion binding]; other site
761193009983	G-X-G motif; other site
761193009984	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
761193009985	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193009986	active site
761193009987	phosphorylation site [posttranslational modification]
761193009988	intermolecular recognition site; other site
761193009989	dimerization interface [polypeptide binding]; other site
761193009990	LytTr DNA-binding domain; Region: LytTR; smart00850
761193009991	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193009992	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193009993	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193009994	DinB family; Region: DinB; cl17821
761193009995	DinB superfamily; Region: DinB_2; pfam12867
761193009996	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
761193009997	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
761193009998	dimer interface [polypeptide binding]; other site
761193009999	active site
761193010000	CoA binding pocket [chemical binding]; other site
761193010001	phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed; Region: PRK05974
761193010002	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
761193010003	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
761193010004	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
761193010005	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
761193010006	GDSL-like Lipase/Acylhydrolase family; Region: Lipase_GDSL_2; pfam13472
761193010007	active site
761193010008	oxyanion hole [active]
761193010009	Predicted carbamoyl transferase, NodU family [Posttranslational modification, protein turnover, chaperones]; Region: COG2192
761193010010	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
761193010011	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
761193010012	active site
761193010013	oxyanion hole [active]
761193010014	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
761193010015	catalytic triad [active]
761193010016	exopolyphosphatase; Region: exo_poly_only; TIGR03706
761193010017	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
761193010018	Protein of unknown function (DUF1624); Region: DUF1624; cl01394
761193010019	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193010020	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193010021	active site
761193010022	phosphorylation site [posttranslational modification]
761193010023	intermolecular recognition site; other site
761193010024	dimerization interface [polypeptide binding]; other site
761193010025	LytTr DNA-binding domain; Region: LytTR; cl04498
761193010026	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
761193010027	Histidine kinase; Region: HisKA_2; pfam07568
761193010028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193010029	ATP binding site [chemical binding]; other site
761193010030	Mg2+ binding site [ion binding]; other site
761193010031	G-X-G motif; other site
761193010032	Bacterial PH domain; Region: DUF304; pfam03703
761193010033	Domain of unknown function (DUF4190); Region: DUF4190; pfam13828
761193010034	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193010035	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
761193010036	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193010037	hydroxyproline-2-epimerase; Provisional; Region: PRK13971
761193010038	Proline racemase; Region: Pro_racemase; pfam05544
761193010039	ornithine cyclodeaminase; Validated; Region: PRK08618
761193010040	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
761193010041	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
761193010042	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
761193010043	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
761193010044	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
761193010045	histidinol dehydrogenase; Region: hisD; TIGR00069
761193010046	NAD binding site [chemical binding]; other site
761193010047	dimerization interface [polypeptide binding]; other site
761193010048	product binding site; other site
761193010049	substrate binding site [chemical binding]; other site
761193010050	zinc binding site [ion binding]; other site
761193010051	catalytic residues [active]
761193010052	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193010053	AAA domain; Region: AAA_21; pfam13304
761193010054	Walker A/P-loop; other site
761193010055	ATP binding site [chemical binding]; other site
761193010056	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
761193010057	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193010058	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193010059	homodimer interface [polypeptide binding]; other site
761193010060	catalytic residue [active]
761193010061	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
761193010062	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
761193010063	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
761193010064	benzoate transport; Region: 2A0115; TIGR00895
761193010065	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193010066	putative substrate translocation pore; other site
761193010067	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
761193010068	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193010069	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193010070	dimer interface [polypeptide binding]; other site
761193010071	phosphorylation site [posttranslational modification]
761193010072	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193010073	ATP binding site [chemical binding]; other site
761193010074	Mg2+ binding site [ion binding]; other site
761193010075	G-X-G motif; other site
761193010076	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
761193010077	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193010078	active site
761193010079	phosphorylation site [posttranslational modification]
761193010080	intermolecular recognition site; other site
761193010081	dimerization interface [polypeptide binding]; other site
761193010082	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
761193010083	DNA binding site [nucleotide binding]
761193010084	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193010085	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193010086	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193010087	L-arabinose isomerase [Carbohydrate transport and metabolism]; Region: AraA; COG2160
761193010088	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cd00578
761193010089	hexamer (dimer of trimers) interface [polypeptide binding]; other site
761193010090	substrate binding site [chemical binding]; other site
761193010091	trimer interface [polypeptide binding]; other site
761193010092	Mn binding site [ion binding]; other site
761193010093	DNA repair protein RadA; Provisional; Region: PRK11823
761193010094	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
761193010095	Walker A motif/ATP binding site; other site
761193010096	ATP binding site [chemical binding]; other site
761193010097	Walker B motif; other site
761193010098	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
761193010099	Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) [Cell envelope biogenesis, outer membrane]; Region: DltE; COG3967
761193010100	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193010101	NAD(P) binding site [chemical binding]; other site
761193010102	active site
761193010103	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
761193010104	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
761193010105	Walker A/P-loop; other site
761193010106	ATP binding site [chemical binding]; other site
761193010107	Q-loop/lid; other site
761193010108	ABC transporter signature motif; other site
761193010109	Walker B; other site
761193010110	D-loop; other site
761193010111	H-loop/switch region; other site
761193010112	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
761193010113	AAA domain; Region: AAA_14; pfam13173
761193010114	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193010115	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193010116	ligand binding site [chemical binding]; other site
761193010117	Predicted membrane protein [Function unknown]; Region: COG2259
761193010118	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193010119	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193010120	ligand binding site [chemical binding]; other site
761193010121	Pleckstrin homology-like domain; Region: PH-like; cl17171
761193010122	flexible hinge region; other site
761193010123	Erythromycin esterase; Region: Erythro_esteras; cl17110
761193010124	Erythromycin esterase; Region: Erythro_esteras; cl17110
761193010125	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
761193010126	This entry represents the putative helicase A859L; Region: T5orf172; smart00974
761193010127	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
761193010128	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
761193010129	5'-nucleotidase; Region: 5-nucleotidase; pfam06189
761193010130	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
761193010131	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193010132	Protein of unknown function (DUF511); Region: DUF511; pfam04373
761193010133	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193010134	sequence-specific DNA binding site [nucleotide binding]; other site
761193010135	salt bridge; other site
761193010136	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
761193010137	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
761193010138	5-oxoprolinase; Region: PLN02666
761193010139	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
761193010140	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
761193010141	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
761193010142	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
761193010143	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
761193010144	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
761193010145	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
761193010146	Walker A/P-loop; other site
761193010147	ATP binding site [chemical binding]; other site
761193010148	Q-loop/lid; other site
761193010149	ABC transporter signature motif; other site
761193010150	Walker B; other site
761193010151	D-loop; other site
761193010152	H-loop/switch region; other site
761193010153	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
761193010154	DHH family; Region: DHH; pfam01368
761193010155	DHHA1 domain; Region: DHHA1; pfam02272
761193010156	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
761193010157	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193010158	Domain of unknown function (DUF718); Region: DUF718; pfam05336
761193010159	Nuclease A inhibitor-like protein; Region: NuiA; pfam07924
761193010160	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
761193010161	Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129
761193010162	dimer interface [polypeptide binding]; other site
761193010163	NADP binding site [chemical binding]; other site
761193010164	catalytic residues [active]
761193010165	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
761193010166	Protein of unknown function (DUF4197); Region: DUF4197; pfam13852
761193010167	InterPro IPR003367:IPR008454; KEGG: hau:Haur_1649 Cna B domain-containing protein; PFAM: Collagen-binding surface protein Cna-like, B region; Thrombospondin, type 3-like repeat; SPTR: Cna B domain protein
761193010168	Cna protein B-type domain; Region: Cna_B; pfam05738
761193010169	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
761193010170	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
761193010171	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
761193010172	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
761193010173	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
761193010174	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
761193010175	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
761193010176	putative ABC transporter; Region: ycf24; CHL00085
761193010177	oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701
761193010178	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
761193010179	putative molybdopterin cofactor binding site [chemical binding]; other site
761193010180	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
761193010181	putative molybdopterin cofactor binding site; other site
761193010182	Glycosyl hydrolase family 14; Region: Glyco_hydro_14; cl03185
761193010183	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193010184	Cadherin repeat-like domain; Region: CA_like; cl15786
761193010185	Ca2+ binding site [ion binding]; other site
761193010186	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193010187	Cadherin repeat-like domain; Region: CA_like; cl15786
761193010188	Ca2+ binding site [ion binding]; other site
761193010189	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193010190	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193010191	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193010192	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193010193	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
761193010194	Uncharacterized conserved protein [Function unknown]; Region: COG1262
761193010195	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
761193010196	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
761193010197	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
761193010198	Walker A/P-loop; other site
761193010199	ATP binding site [chemical binding]; other site
761193010200	Q-loop/lid; other site
761193010201	ABC transporter signature motif; other site
761193010202	Walker B; other site
761193010203	D-loop; other site
761193010204	H-loop/switch region; other site
761193010205	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
761193010206	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193010207	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
761193010208	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
761193010209	B12 binding site [chemical binding]; other site
761193010210	cobalt ligand [ion binding]; other site
761193010211	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
761193010212	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
761193010213	Ribosome-binding factor A; Region: RBFA; pfam02033
761193010214	Chorismate mutase type II; Region: CM_2; cl00693
761193010215	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
761193010216	Prephenate dehydratase; Region: PDT; pfam00800
761193010217	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
761193010218	putative L-Phe binding site [chemical binding]; other site
761193010219	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
761193010220	dimer interface [polypeptide binding]; other site
761193010221	putative tRNA-binding site [nucleotide binding]; other site
761193010222	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
761193010223	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
761193010224	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
761193010225	active site
761193010226	Domain of unknown function (DUF4403); Region: DUF4403; pfam14356
761193010227	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193010228	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193010229	ligand binding site [chemical binding]; other site
761193010230	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
761193010231	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193010232	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193010233	active site
761193010234	phosphorylation site [posttranslational modification]
761193010235	intermolecular recognition site; other site
761193010236	dimerization interface [polypeptide binding]; other site
761193010237	LytTr DNA-binding domain; Region: LytTR; smart00850
761193010238	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193010239	LytTr DNA-binding domain; Region: LytTR; smart00850
761193010240	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
761193010241	non-specific DNA binding site [nucleotide binding]; other site
761193010242	salt bridge; other site
761193010243	sequence-specific DNA binding site [nucleotide binding]; other site
761193010244	Helix-turn-helix domain; Region: HTH_17; pfam12728
761193010245	HsdM N-terminal domain; Region: HsdM_N; pfam12161
761193010246	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
761193010247	Methyltransferase domain; Region: Methyltransf_26; pfam13659
761193010248	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193010249	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
761193010250	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
761193010251	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
761193010252	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193010253	ATP binding site [chemical binding]; other site
761193010254	putative Mg++ binding site [ion binding]; other site
761193010255	Protein of unknown function (DUF2493); Region: DUF2493; pfam10686
761193010256	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
761193010257	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
761193010258	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193010259	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193010260	Predicted membrane protein [Function unknown]; Region: COG4270
761193010261	short chain dehydrogenase; Provisional; Region: PRK06197
761193010262	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
761193010263	putative NAD(P) binding site [chemical binding]; other site
761193010264	active site
761193010265	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
761193010266	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
761193010267	Catalytic site [active]
761193010268	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
761193010269	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
761193010270	active site
761193010271	DNA binding site [nucleotide binding]
761193010272	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
761193010273	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
761193010274	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193010275	active site
761193010276	DNA binding site [nucleotide binding]
761193010277	Int/Topo IB signature motif; other site
761193010278	Archaeal ATPase; Region: Arch_ATPase; pfam01637
761193010279	AAA ATPase domain; Region: AAA_16; pfam13191
761193010280	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
761193010281	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
761193010282	catalytic residues [active]
761193010283	catalytic nucleophile [active]
761193010284	Presynaptic Site I dimer interface [polypeptide binding]; other site
761193010285	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
761193010286	Synaptic Flat tetramer interface [polypeptide binding]; other site
761193010287	Synaptic Site I dimer interface [polypeptide binding]; other site
761193010288	DNA binding site [nucleotide binding]
761193010289	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
761193010290	DNA-binding interface [nucleotide binding]; DNA binding site
761193010291	lagellar hook-associated protein FlgL; Provisional; Region: PRK14692
761193010292	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
761193010293	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
761193010294	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
761193010295	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193010296	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
761193010297	S1 domain; Region: S1_2; pfam13509
761193010298	S1 domain; Region: S1_2; pfam13509
761193010299	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
761193010300	FAD dependent oxidoreductase; Region: DAO; pfam01266
761193010301	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cl10015
761193010302	homotrimer interaction site [polypeptide binding]; other site
761193010303	putative active site [active]
761193010304	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
761193010305	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
761193010306	putative metal binding site [ion binding]; other site
761193010307	fructuronate transporter; Provisional; Region: PRK10034; cl15264
761193010308	GntP family permease; Region: GntP_permease; pfam02447
761193010309	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
761193010310	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
761193010311	intersubunit interface [polypeptide binding]; other site
761193010312	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
761193010313	COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362; KEGG: dfe:Dfer_4588 sugar transferase; PFAM: Bacterial sugar transferase; SPTR: Sugar transferase
761193010314	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
761193010315	Bacterial sugar transferase; Region: Bac_transf; pfam02397
761193010316	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193010317	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193010318	Transposase domain (DUF772); Region: DUF772; pfam05598
761193010319	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
761193010320	Transposase; Region: DEDD_Tnp_IS110; pfam01548
761193010321	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
761193010322	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
761193010323	COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: gem:GM21_2592 glycosyl transferase 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase 2
761193010324	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
761193010325	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
761193010326	metal-binding site
761193010327	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193010328	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
761193010329	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
761193010330	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193010331	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
761193010332	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
761193010333	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
761193010334	inhibitor-cofactor binding pocket; inhibition site
761193010335	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193010336	catalytic residue [active]
761193010337	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
761193010338	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_III; cd01996
761193010339	Ligand Binding Site [chemical binding]; other site
761193010340	imidazole glycerol phosphate synthase subunit HisF; Provisional; Region: PRK01033
761193010341	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
761193010342	substrate binding site [chemical binding]; other site
761193010343	glutamase interaction surface [polypeptide binding]; other site
761193010344	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
761193010345	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
761193010346	putative active site [active]
761193010347	oxyanion strand; other site
761193010348	catalytic triad [active]
761193010349	Methyltransferase FkbM domain; Region: Methyltransf_21; cl17387
761193010350	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
761193010351	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
761193010352	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
761193010353	putative trimer interface [polypeptide binding]; other site
761193010354	putative active site [active]
761193010355	putative substrate binding site [chemical binding]; other site
761193010356	putative CoA binding site [chemical binding]; other site
761193010357	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193010358	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193010359	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193010360	O-Antigen ligase; Region: Wzy_C; pfam04932
761193010361	polysaccharide export inner-membrane protein, BexC/CtrB/KpsE family; Region: BexC_CtrB_KpsE; TIGR01010
761193010362	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
761193010363	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
761193010364	SLBB domain; Region: SLBB; pfam10531
761193010365	SLBB domain; Region: SLBB; pfam10531
761193010366	SLBB domain; Region: SLBB; pfam10531
761193010367	SLBB domain; Region: SLBB; pfam10531
761193010368	amino acid transporter; Region: 2A0306; TIGR00909
761193010369	Vacuole effluxer Atg22 like; Region: ATG22; pfam11700
761193010370	Transposase domain (DUF772); Region: DUF772; pfam05598
761193010371	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
761193010372	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193010373	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
761193010374	Ligand binding site; other site
761193010375	Putative Catalytic site; other site
761193010376	DXD motif; other site
761193010377	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
761193010378	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
761193010379	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
761193010380	PYR/PP interface [polypeptide binding]; other site
761193010381	dimer interface [polypeptide binding]; other site
761193010382	TPP binding site [chemical binding]; other site
761193010383	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193010384	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193010385	NAD(P) binding site [chemical binding]; other site
761193010386	active site
761193010387	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
761193010388	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
761193010389	Ligand binding site; other site
761193010390	Putative Catalytic site; other site
761193010391	DXD motif; other site
761193010392	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
761193010393	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
761193010394	TPP-binding site [chemical binding]; other site
761193010395	dimer interface [polypeptide binding]; other site
761193010396	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
761193010397	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193010398	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
761193010399	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193010400	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
761193010401	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193010402	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
761193010403	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
761193010404	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
761193010405	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193010406	active site
761193010407	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
761193010408	bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and...; Region: arch_bact_SO_family_Moco; cd02109
761193010409	Moco binding site; other site
761193010410	metal coordination site [ion binding]; other site
761193010411	multifunctional aminopeptidase A; Provisional; Region: PRK00913
761193010412	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
761193010413	interface (dimer of trimers) [polypeptide binding]; other site
761193010414	Substrate-binding/catalytic site; other site
761193010415	Zn-binding sites [ion binding]; other site
761193010416	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193010417	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193010418	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193010419	ligand binding site [chemical binding]; other site
761193010420	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193010421	UbiA prenyltransferase family; Region: UbiA; pfam01040
761193010422	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
761193010423	active site
761193010424	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
761193010425	Transposase; Region: DDE_Tnp_ISL3; pfam01610
761193010426	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
761193010427	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
761193010428	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193010429	NAD(P) binding site [chemical binding]; other site
761193010430	active site
761193010431	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
761193010432	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
761193010433	dimer interface [polypeptide binding]; other site
761193010434	decamer (pentamer of dimers) interface [polypeptide binding]; other site
761193010435	catalytic triad [active]
761193010436	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
761193010437	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
761193010438	substrate binding site [chemical binding]; other site
761193010439	ATP binding site [chemical binding]; other site
761193010440	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
761193010441	Leucine-rich repeats; other site
761193010442	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
761193010443	Substrate binding site [chemical binding]; other site
761193010444	Leucine rich repeat; Region: LRR_8; pfam13855
761193010445	Leucine rich repeat; Region: LRR_8; pfam13855
761193010446	Leucine rich repeat; Region: LRR_8; pfam13855
761193010447	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
761193010448	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
761193010449	Transposase; Region: DDE_Tnp_ISL3; pfam01610
761193010450	SPFH domain / Band 7 family; Region: Band_7; pfam01145
761193010451	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
761193010452	Sterol-sensing domain of SREBP cleavage-activation; Region: Sterol-sensing; pfam12349
761193010453	Protein export membrane protein; Region: SecD_SecF; cl14618
761193010454	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
761193010455	active site
761193010456	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
761193010457	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193010458	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
761193010459	AP (apurinic/apyrimidinic) site pocket; other site
761193010460	DNA interaction; other site
761193010461	Metal-binding active site; metal-binding site
761193010462	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193010463	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193010464	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
761193010465	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
761193010466	NADP binding site [chemical binding]; other site
761193010467	active site
761193010468	putative substrate binding site [chemical binding]; other site
761193010469	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
761193010470	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
761193010471	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
761193010472	Ligand binding site; other site
761193010473	Putative Catalytic site; other site
761193010474	DXD motif; other site
761193010475	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
761193010476	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
761193010477	Ligand binding site; other site
761193010478	Putative Catalytic site; other site
761193010479	DXD motif; other site
761193010480	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
761193010481	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
761193010482	dimer interface [polypeptide binding]; other site
761193010483	active site
761193010484	CoA binding pocket [chemical binding]; other site
761193010485	hypothetical protein; Provisional; Region: PRK09956
761193010486	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
761193010487	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
761193010488	Zn2+ binding site [ion binding]; other site
761193010489	Mg2+ binding site [ion binding]; other site
761193010490	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
761193010491	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
761193010492	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
761193010493	acid phosphatase, Burkholderia-type; Region: acid_phos_Burk; TIGR03397
761193010494	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193010495	Peptidase C10 family; Region: Peptidase_C10; pfam01640
761193010496	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193010497	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193010498	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
761193010499	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193010500	phosphonatase-like hydrolase; Region: PhnX-like; TIGR03351
761193010501	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193010502	motif II; other site
761193010503	hydroxyglutarate oxidase; Provisional; Region: PRK11728
761193010504	FAD dependent oxidoreductase TIGR03364; Region: HpnW_proposed
761193010505	Predicted esterase [General function prediction only]; Region: COG0400
761193010506	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193010507	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193010508	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193010509	ligand-binding site [chemical binding]; other site
761193010510	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
761193010511	endonuclease III; Region: ENDO3c; smart00478
761193010512	minor groove reading motif; other site
761193010513	helix-hairpin-helix signature motif; other site
761193010514	substrate binding pocket [chemical binding]; other site
761193010515	active site
761193010516	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
761193010517	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
761193010518	active site
761193010519	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193010520	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193010521	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193010522	Uncharacterized conserved protein (COG2071); Region: DUF2071; pfam09844
761193010523	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193010524	sequence-specific DNA binding site [nucleotide binding]; other site
761193010525	salt bridge; other site
761193010526	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
761193010527	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
761193010528	active site
761193010529	dimer interface [polypeptide binding]; other site
761193010530	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
761193010531	dimer interface [polypeptide binding]; other site
761193010532	active site
761193010533	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193010534	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193010535	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193010536	Coenzyme A binding pocket [chemical binding]; other site
761193010537	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
761193010538	Acyltransferase family; Region: Acyl_transf_3; pfam01757
761193010539	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
761193010540	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
761193010541	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
761193010542	active site
761193010543	trimer interface [polypeptide binding]; other site
761193010544	allosteric site; other site
761193010545	active site lid [active]
761193010546	hexamer (dimer of trimers) interface [polypeptide binding]; other site
761193010547	Lycopene cyclase protein; Region: Lycopene_cycl; pfam05834
761193010548	lycopene cyclase; Region: lycopene_cycl; TIGR01789
761193010549	KEGG: cao:Celal_0896 hypothetical protein; SPTR:  uncharacterized protein
761193010550	COGs: COG4115 conserved hypothetical protein; InterPro IPR009614; KEGG: cyh:Cyan8802_3569 addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin, Txe/YoeB; SPTR: Addiction module toxin, Txe/YoeB family; TIGRFAM: Addiction module toxin, Txe/YoeB
761193010551	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
761193010552	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
761193010553	COGs: COG0320 Lipoate synthase; HAMAP: Lipoate synthase; InterPro IPR003698:IPR006638:IPR007197; KEGG: sli:Slin_0446 lipoic acid synthetase; PFAM: Radical SAM; PRIAM: Lipoyl synthase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Lipoic acid synthetase; TIGRFAM: Lipoate synthase
761193010554	lipoyl synthase; Provisional; Region: PRK05481
761193010555	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193010556	FeS/SAM binding site; other site
761193010557	OsmC-like protein; Region: OsmC; pfam02566
761193010558	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
761193010559	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
761193010560	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
761193010561	active site
761193010562	substrate binding site [chemical binding]; other site
761193010563	Mg2+ binding site [ion binding]; other site
761193010564	flavoprotein, HI0933 family; Region: TIGR00275
761193010565	NlpC/P60 family; Region: NLPC_P60; pfam00877
761193010566	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
761193010567	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193010568	Coenzyme A binding pocket [chemical binding]; other site
761193010569	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
761193010570	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
761193010571	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
761193010572	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
761193010573	catalytic residues [active]
761193010574	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; cl00756
761193010575	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
761193010576	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193010577	S-adenosylmethionine binding site [chemical binding]; other site
761193010578	Right handed beta helix region; Region: Beta_helix; pfam13229
761193010579	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
761193010580	protein binding site [polypeptide binding]; other site
761193010581	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
761193010582	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
761193010583	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193010584	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193010585	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193010586	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193010587	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
761193010588	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
761193010589	ATP binding site [chemical binding]; other site
761193010590	putative Mg++ binding site [ion binding]; other site
761193010591	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193010592	nucleotide binding region [chemical binding]; other site
761193010593	ATP-binding site [chemical binding]; other site
761193010594	DbpA RNA binding domain; Region: DbpA; pfam03880
761193010595	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193010596	AAA domain; Region: AAA_22; pfam13401
761193010597	Walker A motif; other site
761193010598	ATP binding site [chemical binding]; other site
761193010599	Walker B motif; other site
761193010600	arginine finger; other site
761193010601	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
761193010602	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
761193010603	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193010604	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193010605	active site
761193010606	phosphorylation site [posttranslational modification]
761193010607	intermolecular recognition site; other site
761193010608	dimerization interface [polypeptide binding]; other site
761193010609	LytTr DNA-binding domain; Region: LytTR; smart00850
761193010610	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
761193010611	Histidine kinase; Region: His_kinase; pfam06580
761193010612	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
761193010613	Cupin domain; Region: Cupin_2; pfam07883
761193010614	KEGG: sli:Slin_2175 hypothetical protein; SPTR:  uncharacterized protein
761193010615	Protein of unknown function (DUF1111); Region: DUF1111; pfam06537
761193010616	COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910; KEGG: sli:Slin_4224 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, plug; SPTR: TonB-dependent receptor plug
761193010617	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193010618	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193010619	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193010620	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193010621	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
761193010622	Protein export membrane protein; Region: SecD_SecF; cl14618
761193010623	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193010624	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193010625	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193010626	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
761193010627	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
761193010628	MarR family; Region: MarR_2; pfam12802
761193010629	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193010630	putative active site [active]
761193010631	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
761193010632	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
761193010633	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
761193010634	Surface antigen; Region: Bac_surface_Ag; pfam01103
761193010635	Outer membrane efflux protein; Region: OEP; pfam02321
761193010636	Outer membrane efflux protein; Region: OEP; pfam02321
761193010637	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
761193010638	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
761193010639	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193010640	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
761193010641	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193010642	Walker A/P-loop; other site
761193010643	ATP binding site [chemical binding]; other site
761193010644	Q-loop/lid; other site
761193010645	ABC transporter signature motif; other site
761193010646	Walker B; other site
761193010647	D-loop; other site
761193010648	H-loop/switch region; other site
761193010649	Peptidase S8 family domain, uncharacterized subfamily 9; Region: Peptidases_S8_9; cd07493
761193010650	active site
761193010651	catalytic triad [active]
761193010652	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193010653	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
761193010654	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
761193010655	catalytic residues [active]
761193010656	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
761193010657	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14521
761193010658	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
761193010659	RimM N-terminal domain; Region: RimM; pfam01782
761193010660	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
761193010661	putative carbohydrate kinase; Provisional; Region: PRK10565
761193010662	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
761193010663	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
761193010664	putative substrate binding site [chemical binding]; other site
761193010665	putative ATP binding site [chemical binding]; other site
761193010666	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
761193010667	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
761193010668	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
761193010669	NAD(P) binding site [chemical binding]; other site
761193010670	homodimer interface [polypeptide binding]; other site
761193010671	substrate binding site [chemical binding]; other site
761193010672	active site
761193010673	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193010674	TIGR01777 family protein; Region: yfcH
761193010675	NAD(P) binding site [chemical binding]; other site
761193010676	active site
761193010677	excinuclease ABC subunit B; Provisional; Region: PRK05298
761193010678	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193010679	ATP binding site [chemical binding]; other site
761193010680	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193010681	nucleotide binding region [chemical binding]; other site
761193010682	ATP-binding site [chemical binding]; other site
761193010683	Ultra-violet resistance protein B; Region: UvrB; pfam12344
761193010684	UvrB/uvrC motif; Region: UVR; pfam02151
761193010685	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
761193010686	active site
761193010687	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
761193010688	hypothetical protein; Provisional; Region: PRK09256
761193010689	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193010690	Coenzyme A binding pocket [chemical binding]; other site
761193010691	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
761193010692	active site
761193010693	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
761193010694	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
761193010695	dimerization interface [polypeptide binding]; other site
761193010696	active site
761193010697	Histidine kinase; Region: HisKA_3; pfam07730
761193010698	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
761193010699	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193010700	ATP binding site [chemical binding]; other site
761193010701	Mg2+ binding site [ion binding]; other site
761193010702	G-X-G motif; other site
761193010703	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193010704	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193010705	active site
761193010706	phosphorylation site [posttranslational modification]
761193010707	intermolecular recognition site; other site
761193010708	dimerization interface [polypeptide binding]; other site
761193010709	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
761193010710	DNA binding residues [nucleotide binding]
761193010711	dimerization interface [polypeptide binding]; other site
761193010712	Fatty acid desaturase; Region: FA_desaturase; pfam00487
761193010713	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
761193010714	putative di-iron ligands [ion binding]; other site
761193010715	putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional; Region: PRK11930
761193010716	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
761193010717	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
761193010718	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
761193010719	active site
761193010720	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
761193010721	dimer interface [polypeptide binding]; other site
761193010722	substrate binding site [chemical binding]; other site
761193010723	catalytic residues [active]
761193010724	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193010725	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
761193010726	InterPro IPR012910:IPR000531; KEGG: mtt:Ftrac_3123 TonB-dependent receptor; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: TonB-dependent receptor
761193010727	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193010728	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193010729	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193010730	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; cl09754
761193010731	KEGG: bvu:BVU_1138 hypothetical protein; SPTR:  uncharacterized protein
761193010732	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
761193010733	methionine aminotransferase; Validated; Region: PRK09082
761193010734	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193010735	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193010736	homodimer interface [polypeptide binding]; other site
761193010737	catalytic residue [active]
761193010738	NlpC/P60 family; Region: NLPC_P60; pfam00877
761193010739	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193010740	dimerization interface [polypeptide binding]; other site
761193010741	putative DNA binding site [nucleotide binding]; other site
761193010742	putative Zn2+ binding site [ion binding]; other site
761193010743	Methyltransferase domain; Region: Methyltransf_31; pfam13847
761193010744	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193010745	S-adenosylmethionine binding site [chemical binding]; other site
761193010746	putative acetyltransferase; Provisional; Region: PRK03624
761193010747	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193010748	Coenzyme A binding pocket [chemical binding]; other site
761193010749	Cupin domain; Region: Cupin_2; cl17218
761193010750	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193010751	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193010752	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
761193010753	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
761193010754	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
761193010755	active site
761193010756	gliding motility-associated lipoprotein GldJ; Region: GldJ_short; TIGR03530
761193010757	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
761193010758	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
761193010759	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
761193010760	active site
761193010761	putative DNA-binding cleft [nucleotide binding]; other site
761193010762	dimer interface [polypeptide binding]; other site
761193010763	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
761193010764	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
761193010765	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_e; cd04192
761193010766	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
761193010767	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
761193010768	NodB motif; other site
761193010769	active site
761193010770	catalytic site [active]
761193010771	metal binding site [ion binding]; metal-binding site
761193010772	Protein of unknown function (DUF3267); Region: DUF3267; pfam11667
761193010773	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193010774	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
761193010775	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193010776	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
761193010777	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193010778	Walker A motif; other site
761193010779	ATP binding site [chemical binding]; other site
761193010780	Walker B motif; other site
761193010781	arginine finger; other site
761193010782	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3825
761193010783	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
761193010784	RNA methyltransferase, RsmE family; Region: TIGR00046
761193010785	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193010786	LytTr DNA-binding domain; Region: LytTR; smart00850
761193010787	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
761193010788	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
761193010789	Fatty acid desaturase; Region: FA_desaturase; pfam00487
761193010790	Di-iron ligands [ion binding]; other site
761193010791	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C); Region: NT5C; cl17836
761193010792	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193010793	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
761193010794	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
761193010795	CoA-ligase; Region: Ligase_CoA; pfam00549
761193010796	Protein of unknown function (DUF1361); Region: DUF1361; pfam07099
761193010797	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
761193010798	DNA-binding site [nucleotide binding]; DNA binding site
761193010799	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
761193010800	UTRA domain; Region: UTRA; pfam07702
761193010801	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; Region: Oxidored_q2; cl00492
761193010802	prolyl-tRNA synthetase; Provisional; Region: PRK08661
761193010803	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
761193010804	dimer interface [polypeptide binding]; other site
761193010805	motif 1; other site
761193010806	active site
761193010807	motif 2; other site
761193010808	motif 3; other site
761193010809	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
761193010810	anticodon binding site; other site
761193010811	zinc-binding site [ion binding]; other site
761193010812	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
761193010813	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
761193010814	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
761193010815	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
761193010816	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
761193010817	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
761193010818	COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005839:IPR006467:IPR006638:IPR013848:IPR 007197:IPR002792; KEGG: dfe:Dfer_0444 MiaB-like tRNA modifying enzyme; PFAM: Radical SAM; Methylthiotransferase, N-terminal; Deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: MiaB-like tRNA modifying enzyme; TIGRFAM: MiaB-like tRNA modifying enzyme; Methylthiotransferase
761193010819	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
761193010820	MiaB-like tRNA modifying enzyme; Region: MiaB-like-C; TIGR01579
761193010821	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193010822	FeS/SAM binding site; other site
761193010823	CoA binding domain; Region: CoA_binding_2; pfam13380
761193010824	HNH endonuclease; Region: HNH_3; pfam13392
761193010825	molybdenum cofactor biosynthesis protein A, bacterial; Region: moaA; TIGR02666
761193010826	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193010827	FeS/SAM binding site; other site
761193010828	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
761193010829	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
761193010830	DNA-binding site [nucleotide binding]; DNA binding site
761193010831	RNA-binding motif; other site
761193010832	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
761193010833	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
761193010834	dimer interface [polypeptide binding]; other site
761193010835	anticodon binding site; other site
761193010836	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
761193010837	homodimer interface [polypeptide binding]; other site
761193010838	motif 1; other site
761193010839	active site
761193010840	motif 2; other site
761193010841	GAD domain; Region: GAD; pfam02938
761193010842	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
761193010843	active site
761193010844	motif 3; other site
761193010845	RNA pol II promoter Fmp27 protein domain; Region: Fmp27_WPPW; pfam10359
761193010846	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193010847	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193010848	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193010849	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193010850	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193010851	ligand binding site [chemical binding]; other site
761193010852	flexible hinge region; other site
761193010853	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193010854	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
761193010855	DNA binding residues [nucleotide binding]
761193010856	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
761193010857	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193010858	N-terminal plug; other site
761193010859	ligand-binding site [chemical binding]; other site
761193010860	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
761193010861	active site
761193010862	metal binding site [ion binding]; metal-binding site
761193010863	homotetramer interface [polypeptide binding]; other site
761193010864	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
761193010865	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
761193010866	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
761193010867	four helix bundle protein; Region: TIGR02436
761193010868	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187
761193010869	Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles; Region: ttLC_FACS_AlkK_like; cd12119
761193010870	dimer interface [polypeptide binding]; other site
761193010871	acyl-activating enzyme (AAE) consensus motif; other site
761193010872	putative active site [active]
761193010873	AMP binding site [chemical binding]; other site
761193010874	putative CoA binding site [chemical binding]; other site
761193010875	von Willebrand factor type A domain; Region: VWA_2; pfam13519
761193010876	metal ion-dependent adhesion site (MIDAS); other site
761193010877	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
761193010878	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
761193010879	NAD(P) binding site [chemical binding]; other site
761193010880	homotetramer interface [polypeptide binding]; other site
761193010881	homodimer interface [polypeptide binding]; other site
761193010882	active site
761193010883	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
761193010884	Predicted ATPase [General function prediction only]; Region: COG4637
761193010885	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193010886	Walker A/P-loop; other site
761193010887	ATP binding site [chemical binding]; other site
761193010888	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193010889	Walker B; other site
761193010890	D-loop; other site
761193010891	H-loop/switch region; other site
761193010892	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
761193010893	dimer interface [polypeptide binding]; other site
761193010894	active site
761193010895	trehalose synthase-fused probable maltokinase; Region: TreS_Cterm; TIGR02457
761193010896	Uncharacterized protein, probably involved in trehalose biosynthesis [Carbohydrate transport and metabolism]; Region: Ble; COG3281
761193010897	Predicted acyl esterases [General function prediction only]; Region: COG2936
761193010898	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193010899	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
761193010900	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
761193010901	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
761193010902	G1 box; other site
761193010903	putative GEF interaction site [polypeptide binding]; other site
761193010904	GTP/Mg2+ binding site [chemical binding]; other site
761193010905	Switch I region; other site
761193010906	G2 box; other site
761193010907	G3 box; other site
761193010908	Switch II region; other site
761193010909	G4 box; other site
761193010910	G5 box; other site
761193010911	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
761193010912	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
761193010913	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
761193010914	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
761193010915	active site
761193010916	M28 Zn-Peptidases containing a PA domain insert and associated with a PDZ domain; Region: M28_like_PA_PDZ_associated; cd05663
761193010917	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193010918	metal binding site [ion binding]; metal-binding site
761193010919	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
761193010920	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
761193010921	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
761193010922	Mechanosensitive ion channel; Region: MS_channel; pfam00924
761193010923	pantothenate kinase; Reviewed; Region: PRK13320
761193010924	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
761193010925	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
761193010926	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
761193010927	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193010928	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
761193010929	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
761193010930	FecR protein; Region: FecR; pfam04773
761193010931	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193010932	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193010933	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193010934	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193010935	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193010936	SusD family; Region: SusD; pfam07980
761193010937	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193010938	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193010939	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193010940	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193010941	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193010942	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193010943	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193010944	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193010945	Cytochrome c; Region: Cytochrom_C; pfam00034
761193010946	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
761193010947	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193010948	Sulfatase; Region: Sulfatase; pfam00884
761193010949	NPCBM/NEW2 domain; Region: NPCBM; pfam08305
761193010950	He_PIG associated, NEW1 domain of bacterial glycohydrolase; Region: He_PIG_assoc; pfam10632
761193010951	Putative Ig domain; Region: He_PIG; pfam05345
761193010952	alpha-galactosidase; Region: PLN02808; cl17638
761193010953	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
761193010954	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
761193010955	putative active site [active]
761193010956	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193010957	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193010958	Walker A/P-loop; other site
761193010959	ATP binding site [chemical binding]; other site
761193010960	Q-loop/lid; other site
761193010961	ABC transporter signature motif; other site
761193010962	Walker B; other site
761193010963	D-loop; other site
761193010964	H-loop/switch region; other site
761193010965	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193010966	catalytic residues [active]
761193010967	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
761193010968	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193010969	ligand binding site [chemical binding]; other site
761193010970	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
761193010971	Glycosyl hydrolase families 32 and 68, which for the clan GH-J; Region: GH_J; cd08979
761193010972	active site
761193010973	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193010974	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193010975	Cytochrome c; Region: Cytochrom_C; pfam00034
761193010976	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
761193010977	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
761193010978	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193010979	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193010980	Transposase IS200 like; Region: Y1_Tnp; cl00848
761193010981	KEGG: cbh:CLC_3090 hypothetical protein; SPTR:  membrane protein
761193010982	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
761193010983	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
761193010984	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
761193010985	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
761193010986	Ceramidase; Region: Ceramidase; pfam05875
761193010987	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
761193010988	Asp-box motif; other site
761193010989	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193010990	Sulfatase; Region: Sulfatase; pfam00884
761193010991	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193010992	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193010993	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193010994	Cytochrome c; Region: Cytochrom_C; pfam00034
761193010995	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
761193010996	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
761193010997	Cu(I) binding site [ion binding]; other site
761193010998	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
761193010999	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
761193011000	Walker A/P-loop; other site
761193011001	ATP binding site [chemical binding]; other site
761193011002	Q-loop/lid; other site
761193011003	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
761193011004	Q-loop/lid; other site
761193011005	ABC transporter signature motif; other site
761193011006	Walker B; other site
761193011007	D-loop; other site
761193011008	H-loop/switch region; other site
761193011009	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
761193011010	Flavoprotein; Region: Flavoprotein; pfam02441
761193011011	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
761193011012	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
761193011013	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193011014	OstA-like protein; Region: OstA_2; pfam13100
761193011015	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
761193011016	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193011017	Carboxylesterase family; Region: COesterase; pfam00135
761193011018	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
761193011019	substrate binding pocket [chemical binding]; other site
761193011020	catalytic triad [active]
761193011021	Abhydrolase family; Region: Abhydrolase_7; pfam12715
761193011022	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
761193011023	metal coordination site [ion binding]; other site
761193011024	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
761193011025	Domain of unknown function DUF21; Region: DUF21; pfam01595
761193011026	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
761193011027	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
761193011028	Transporter associated domain; Region: CorC_HlyC; smart01091
761193011029	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
761193011030	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
761193011031	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
761193011032	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
761193011033	active site
761193011034	catalytic site [active]
761193011035	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
761193011036	putative ligand binding site [chemical binding]; other site
761193011037	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
761193011038	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193011039	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193011040	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193011041	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193011042	cyanophycin synthetase; Provisional; Region: PRK14016
761193011043	ATP-grasp domain; Region: ATP-grasp_4; cl17255
761193011044	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
761193011045	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
761193011046	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
761193011047	proposed catalytic triad [active]
761193011048	active site nucleophile [active]
761193011049	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
761193011050	catalytic nucleophile [active]
761193011051	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
761193011052	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
761193011053	TIGR02687 family protein; Region: TIGR02687
761193011054	PglZ domain; Region: PglZ; pfam08665
761193011055	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
761193011056	Divergent AAA domain; Region: AAA_4; pfam04326
761193011057	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
761193011058	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
761193011059	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
761193011060	HipA-like N-terminal domain; Region: HipA_N; pfam07805
761193011061	HipA-like C-terminal domain; Region: HipA_C; pfam07804
761193011062	HipA N-terminal domain; Region: Couple_hipA; pfam13657
761193011063	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193011064	non-specific DNA binding site [nucleotide binding]; other site
761193011065	salt bridge; other site
761193011066	sequence-specific DNA binding site [nucleotide binding]; other site
761193011067	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
761193011068	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
761193011069	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
761193011070	Prodigal; manually curated
761193011071	COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: bth:BT_2763 transposase; PFAM: Transposase, mutator type; SPTR: Transposase
761193011072	Transposase, Mutator family; Region: Transposase_mut; pfam00872
761193011073	MULE transposase domain; Region: MULE; pfam10551
761193011074	AAA domain; Region: AAA_11; pfam13086
761193011075	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193011076	ATP binding site [chemical binding]; other site
761193011077	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
761193011078	putative Mg++ binding site [ion binding]; other site
761193011079	AAA domain; Region: AAA_12; pfam13087
761193011080	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1483
761193011081	Protein of unknown function (DUF499); Region: DUF499; pfam04465
761193011082	SPTR: Transposase IS4 family protein
761193011083	DEAD-like helicases superfamily; Region: DEXDc; smart00487
761193011084	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193011085	ATP binding site [chemical binding]; other site
761193011086	putative Mg++ binding site [ion binding]; other site
761193011087	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193011088	nucleotide binding region [chemical binding]; other site
761193011089	ATP-binding site [chemical binding]; other site
761193011090	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
761193011091	COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: cao:Celal_3609 transcriptional regulator; PFAM: ATPase associated with various cellular activities, AAA-4; SPTR: ATP-dependent DNA helicase
761193011092	Divergent AAA domain; Region: AAA_4; pfam04326
761193011093	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
761193011094	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
761193011095	Toprim domain; Region: Toprim_3; pfam13362
761193011096	active site
761193011097	metal binding site [ion binding]; metal-binding site
761193011098	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193011099	active site
761193011100	DNA binding site [nucleotide binding]
761193011101	Int/Topo IB signature motif; other site
761193011102	Uncharacterized conserved protein [Function unknown]; Region: COG0327
761193011103	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
761193011104	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
761193011105	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
761193011106	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
761193011107	Putative zinc ribbon domain; Region: DUF164; pfam02591
761193011108	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u2; cd11494
761193011109	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
761193011110	Na binding site [ion binding]; other site
761193011111	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
761193011112	classical (c) SDRs; Region: SDR_c; cd05233
761193011113	NAD(P) binding site [chemical binding]; other site
761193011114	active site
761193011115	SnoaL-like domain; Region: SnoaL_2; pfam12680
761193011116	short chain dehydrogenase; Provisional; Region: PRK07035
761193011117	classical (c) SDRs; Region: SDR_c; cd05233
761193011118	NAD(P) binding site [chemical binding]; other site
761193011119	active site
761193011120	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
761193011121	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
761193011122	folate binding site [chemical binding]; other site
761193011123	NADP+ binding site [chemical binding]; other site
761193011124	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193011125	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193011126	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193011127	ligand binding site [chemical binding]; other site
761193011128	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
761193011129	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
761193011130	Ligand Binding Site [chemical binding]; other site
761193011131	TilS substrate C-terminal domain; Region: TilS_C; smart00977
761193011132	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193011133	Trehalose utilisation; Region: ThuA; pfam06283
761193011134	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193011135	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193011136	Cytochrome c; Region: Cytochrom_C; cl11414
761193011137	Carbohydrate Binding Module 6 (CBM6); many are appended to glycoside hydrolase (GH) family 11 and GH43 xylanase domains; Region: CBM6_xylanase-like; cd04084
761193011138	ligand binding site [chemical binding]; other site
761193011139	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
761193011140	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
761193011141	nudix motif; other site
761193011142	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
761193011143	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
761193011144	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193011145	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193011146	Walker A/P-loop; other site
761193011147	ATP binding site [chemical binding]; other site
761193011148	Q-loop/lid; other site
761193011149	ABC transporter signature motif; other site
761193011150	Walker B; other site
761193011151	D-loop; other site
761193011152	H-loop/switch region; other site
761193011153	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
761193011154	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193011155	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193011156	catalytic residue [active]
761193011157	LemA family; Region: LemA; cl00742
761193011158	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193011159	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193011160	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193011161	DNA binding residues [nucleotide binding]
761193011162	TraB family; Region: TraB; pfam01963
761193011163	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
761193011164	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
761193011165	putative active site [active]
761193011166	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
761193011167	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
761193011168	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
761193011169	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
761193011170	NAD(P) binding site [chemical binding]; other site
761193011171	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
761193011172	short chain dehydrogenase; Provisional; Region: PRK07677
761193011173	Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR; Region: TER_DECR_SDR_a; cd05369
761193011174	NAD(P) binding site [chemical binding]; other site
761193011175	substrate binding site [chemical binding]; other site
761193011176	homotetramer interface [polypeptide binding]; other site
761193011177	active site
761193011178	homodimer interface [polypeptide binding]; other site
761193011179	enoyl-CoA hydratase; Provisional; Region: PRK06142
761193011180	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
761193011181	substrate binding site [chemical binding]; other site
761193011182	oxyanion hole (OAH) forming residues; other site
761193011183	trimer interface [polypeptide binding]; other site
761193011184	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
761193011185	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
761193011186	homodimer interface [polypeptide binding]; other site
761193011187	substrate-cofactor binding pocket; other site
761193011188	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193011189	catalytic residue [active]
761193011190	CHC2 zinc finger; Region: zf-CHC2; cl17510
761193011191	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
761193011192	active site
761193011193	metal binding site [ion binding]; metal-binding site
761193011194	interdomain interaction site; other site
761193011195	AAA domain; Region: AAA_25; pfam13481
761193011196	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193011197	active site
761193011198	DNA binding site [nucleotide binding]
761193011199	Int/Topo IB signature motif; other site
761193011200	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
761193011201	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193011202	active site
761193011203	DNA binding site [nucleotide binding]
761193011204	Int/Topo IB signature motif; other site
761193011205	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193011206	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193011207	non-specific DNA binding site [nucleotide binding]; other site
761193011208	salt bridge; other site
761193011209	sequence-specific DNA binding site [nucleotide binding]; other site
761193011210	Winged helix-turn helix; Region: HTH_29; pfam13551
761193011211	Homeodomain-like domain; Region: HTH_23; pfam13384
761193011212	Prodigal; manually curated
761193011213	Prodigal; manually curated
761193011214	KEGG: cth:Cthe_3205 hypothetical protein; SPTR:  uncharacterized protein
761193011215	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cl13853
761193011216	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cd09726
761193011217	COGs: COG3415 Transposase and inactivated derivatives; InterPro IPR001523; KEGG: sli:Slin_5275 transposase; PFAM: Paired box protein, N-terminal; SPTR: Transposase and inactivated derivatives-like protein; manually curated
761193011218	Homeodomain-like domain; Region: HTH_23; pfam13384
761193011219	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193011220	Homeodomain-like domain; Region: HTH_32; pfam13565
761193011221	Winged helix-turn helix; Region: HTH_33; pfam13592
761193011222	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193011223	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193011224	InterPro IPR011742:IPR013383; KEGG: cth:Cthe_2057 CRISPR-associated TM1812 family protein; PFAM: CRISPR-associated protein, TM1812; SPTR: CRISPR-associated protein, Csx2 family; TIGRFAM: CRISPR-associated protein, TM1812; CRISPR-associated protein DxTHG, conserved site
761193011225	CRISPR-associated (Cas) DxTHG family; Region: Cas_DxTHG; pfam09455
761193011226	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cd09732
761193011227	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
761193011228	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
761193011229	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
761193011230	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193011231	KEGG: drt:Dret_2521 hypothetical protein; SPTR:  uncharacterized protein
761193011232	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
761193011233	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
761193011234	Active site serine [active]
761193011235	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
761193011236	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193011237	Protein of unknown function (DUF2721); Region: DUF2721; pfam11026
761193011238	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
761193011239	dimer interface [polypeptide binding]; other site
761193011240	active site
761193011241	ADP-ribose binding site [chemical binding]; other site
761193011242	nudix motif; other site
761193011243	metal binding site [ion binding]; metal-binding site
761193011244	HTH domain; Region: HTH_11; cl17392
761193011245	peptidase T; Region: peptidase-T; TIGR01882
761193011246	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
761193011247	metal binding site [ion binding]; metal-binding site
761193011248	dimer interface [polypeptide binding]; other site
761193011249	MG2 domain; Region: A2M_N; pfam01835
761193011250	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193011251	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
761193011252	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193011253	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193011254	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193011255	AAA ATPase domain; Region: AAA_16; pfam13191
761193011256	Archaeal ATPase; Region: Arch_ATPase; pfam01637
761193011257	KEGG: sli:Slin_5732 hypothetical protein; SPTR:  uncharacterized protein
761193011258	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193011259	InterPro IPR002559; KEGG: app:CAP2UW1_1881 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein
761193011260	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
761193011261	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
761193011262	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
761193011263	Transglycosylase; Region: Transgly; pfam00912
761193011264	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
761193011265	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
761193011266	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
761193011267	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
761193011268	A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; cl17448
761193011269	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
761193011270	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
761193011271	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
761193011272	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
761193011273	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
761193011274	Putative amidoligase enzyme (DUF2126); Region: DUF2126; pfam09899
761193011275	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4196
761193011276	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
761193011277	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193011278	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
761193011279	CARDB; Region: CARDB; pfam07705
761193011280	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
761193011281	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
761193011282	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
761193011283	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
761193011284	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193011285	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193011286	malate:quinone oxidoreductase; Validated; Region: PRK05257
761193011287	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
761193011288	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011289	TPR motif; other site
761193011290	Tetratricopeptide repeat; Region: TPR_16; pfam13432
761193011291	binding surface
761193011292	TPR repeat; Region: TPR_11; pfam13414
761193011293	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011294	binding surface
761193011295	TPR motif; other site
761193011296	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193011297	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
761193011298	ATP binding site [chemical binding]; other site
761193011299	active site
761193011300	substrate binding site [chemical binding]; other site
761193011301	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
761193011302	anti sigma factor interaction site; other site
761193011303	regulatory phosphorylation site [posttranslational modification]; other site
761193011304	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
761193011305	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
761193011306	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
761193011307	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
761193011308	active site
761193011309	dimer interface [polypeptide binding]; other site
761193011310	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
761193011311	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
761193011312	active site
761193011313	FMN binding site [chemical binding]; other site
761193011314	substrate binding site [chemical binding]; other site
761193011315	3Fe-4S cluster binding site [ion binding]; other site
761193011316	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
761193011317	domain interface; other site
761193011318	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
761193011319	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
761193011320	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
761193011321	dimerization interface [polypeptide binding]; other site
761193011322	ATP binding site [chemical binding]; other site
761193011323	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
761193011324	dimerization interface [polypeptide binding]; other site
761193011325	ATP binding site [chemical binding]; other site
761193011326	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
761193011327	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
761193011328	putative active site [active]
761193011329	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193011330	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193011331	Walker A/P-loop; other site
761193011332	ATP binding site [chemical binding]; other site
761193011333	Q-loop/lid; other site
761193011334	ABC transporter signature motif; other site
761193011335	Walker B; other site
761193011336	D-loop; other site
761193011337	H-loop/switch region; other site
761193011338	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
761193011339	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193011340	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193011341	non-specific DNA binding site [nucleotide binding]; other site
761193011342	salt bridge; other site
761193011343	sequence-specific DNA binding site [nucleotide binding]; other site
761193011344	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
761193011345	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
761193011346	substrate binding site [chemical binding]; other site
761193011347	hexamer interface [polypeptide binding]; other site
761193011348	metal binding site [ion binding]; metal-binding site
761193011349	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193011350	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193011351	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
761193011352	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
761193011353	DNA binding site [nucleotide binding]
761193011354	active site
761193011355	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a...; Region: Nudix_Hydrolase_1; cd03674
761193011356	nudix motif; other site
761193011357	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
761193011358	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011359	TPR motif; other site
761193011360	binding surface
761193011361	Bifunctional nuclease; Region: DNase-RNase; pfam02577
761193011362	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
761193011363	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
761193011364	Ligand Binding Site [chemical binding]; other site
761193011365	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
761193011366	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
761193011367	Ligand binding site [chemical binding]; other site
761193011368	Electron transfer flavoprotein domain; Region: ETF; pfam01012
761193011369	Red chlorophyll catabolite reductase (RCC reductase); Region: RCC_reductase; cl05747
761193011370	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14329
761193011371	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
761193011372	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193011373	FeS/SAM binding site; other site
761193011374	TRAM domain; Region: TRAM; pfam01938
761193011375	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193011376	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
761193011377	Walker A motif; other site
761193011378	ATP binding site [chemical binding]; other site
761193011379	Walker B motif; other site
761193011380	arginine finger; other site
761193011381	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
761193011382	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; cl05442
761193011383	Dam-replacing family; Region: DRP; pfam06044
761193011384	Uncharacterized conserved protein [Function unknown]; Region: COG5646
761193011385	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193011386	dimer interface [polypeptide binding]; other site
761193011387	phosphorylation site [posttranslational modification]
761193011388	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193011389	ATP binding site [chemical binding]; other site
761193011390	Mg2+ binding site [ion binding]; other site
761193011391	G-X-G motif; other site
761193011392	Glycosyl hydrolase families 32 and 68, which for the clan GH-J; Region: GH_J; cd08979
761193011393	active site
761193011394	sucrose-phosphate synthase, putative, glycosyltransferase domain; Region: sucr_P_syn_N; TIGR02472
761193011395	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
761193011396	putative ADP-binding pocket [chemical binding]; other site
761193011397	sucrose phosphate synthase, sucrose phosphatase-like domain, bacterial; Region: sucr_syn_bact_C; TIGR02471
761193011398	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193011399	active site
761193011400	motif I; other site
761193011401	motif II; other site
761193011402	COGs: COG3004 Na+/H+ antiporter; HAMAP: Na+/H+ antiporter NhaA; InterPro IPR004670; KEGG: fps:FP1774 Na+/H+ antiporter; PFAM: Na+/H+ antiporter NhaA; SPTR: Na(+)/H(+) antiporter nhaA; TIGRFAM: Na+/H+ antiporter NhaA
761193011403	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09560
761193011404	Domain of unknown function (DUF4386); Region: DUF4386; pfam14329
761193011405	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193011406	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193011407	ligand binding site [chemical binding]; other site
761193011408	flexible hinge region; other site
761193011409	putative beta-lysine N-acetyltransferase; Region: GNAT_ablB; TIGR03827
761193011410	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
761193011411	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
761193011412	Cu(I) binding site [ion binding]; other site
761193011413	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
761193011414	YHYH protein; Region: YHYH; pfam14240
761193011415	DoxX-like family; Region: DoxX_2; pfam13564
761193011416	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
761193011417	putative hydrophobic ligand binding site [chemical binding]; other site
761193011418	KEGG: cpi:Cpin_1760 hypothetical protein; SPTR:  uncharacterized protein
761193011419	DinB superfamily; Region: DinB_2; pfam12867
761193011420	Domain of unknown function (DUF4180); Region: DUF4180; pfam13788
761193011421	COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterPro IPR005481:IPR005479:IPR005480:IPR006275; KEGG: dfe:Dfer_2476 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl phosphate synthetase, large subunit, ATP-binding; Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, oligomerisation; PRIAM: Carbamoyl-phosphate synthase (ammonia); SPTR: Carbamoyl-phosphate synthase, large subunit; TIGRFAM: Carbamoyl phosphate synthase, large subunit, glutamine-dependent
761193011422	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
761193011423	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
761193011424	ATP-grasp domain; Region: ATP-grasp_4; cl17255
761193011425	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
761193011426	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
761193011427	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
761193011428	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
761193011429	ATP-grasp domain; Region: ATP-grasp_4; cl17255
761193011430	InterPro IPR003790; KEGG: dfe:Dfer_5721 protein of unknown function DUF187; PFAM: Protein of unknown function DUF187; SPTR:  uncharacterized protein
761193011431	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
761193011432	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
761193011433	Predicted amidohydrolase [General function prediction only]; Region: COG0388
761193011434	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_7; cd07585
761193011435	putative active site [active]
761193011436	catalytic triad [active]
761193011437	putative dimer interface [polypeptide binding]; other site
761193011438	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
761193011439	MoaE homodimer interface [polypeptide binding]; other site
761193011440	MoaD interaction [polypeptide binding]; other site
761193011441	active site residues [active]
761193011442	phosphodiesterase YaeI; Provisional; Region: PRK11340
761193011443	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
761193011444	putative active site [active]
761193011445	putative metal binding site [ion binding]; other site
761193011446	Predicted acetyltransferase [General function prediction only]; Region: COG2388
761193011447	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
761193011448	FAD binding domain; Region: FAD_binding_4; pfam01565
761193011449	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
761193011450	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
761193011451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193011452	putative substrate translocation pore; other site
761193011453	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193011454	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193011455	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
761193011456	beta-lactamase TEM; Provisional; Region: PRK15442
761193011457	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
761193011458	probable polyamine oxidase; Region: PLN02268
761193011459	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193011460	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
761193011461	NADH(P)-binding; Region: NAD_binding_10; pfam13460
761193011462	NAD(P) binding site [chemical binding]; other site
761193011463	putative active site [active]
761193011464	Rifampin ADP-ribosyl transferase; Region: Arr-ms; pfam12120
761193011465	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
761193011466	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
761193011467	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193011468	ATP binding site [chemical binding]; other site
761193011469	putative Mg++ binding site [ion binding]; other site
761193011470	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
761193011471	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193011472	Walker A motif; other site
761193011473	ATP binding site [chemical binding]; other site
761193011474	Walker B motif; other site
761193011475	arginine finger; other site
761193011476	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193011477	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193011478	Prodigal; manually curated
761193011479	KEGG: dfe:Dfer_4185 hypothetical protein; SPTR:  uncharacterized protein
761193011480	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
761193011481	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193011482	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
761193011483	Uncharacterized conserved protein [Function unknown]; Region: COG3391
761193011484	Protein of unknown function (DUF2938); Region: DUF2938; pfam11158
761193011485	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
761193011486	dimanganese center [ion binding]; other site
761193011487	Uncharacterized conserved protein [Function unknown]; Region: COG1633
761193011488	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
761193011489	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
761193011490	catalytic residues [active]
761193011491	PAS domain S-box; Region: sensory_box; TIGR00229
761193011492	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193011493	putative active site [active]
761193011494	heme pocket [chemical binding]; other site
761193011495	PAS fold; Region: PAS_3; pfam08447
761193011496	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
761193011497	heme pocket [chemical binding]; other site
761193011498	putative active site [active]
761193011499	PAS domain S-box; Region: sensory_box; TIGR00229
761193011500	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193011501	putative active site [active]
761193011502	heme pocket [chemical binding]; other site
761193011503	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193011504	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193011505	putative active site [active]
761193011506	heme pocket [chemical binding]; other site
761193011507	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193011508	putative active site [active]
761193011509	heme pocket [chemical binding]; other site
761193011510	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193011511	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193011512	dimer interface [polypeptide binding]; other site
761193011513	phosphorylation site [posttranslational modification]
761193011514	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193011515	ATP binding site [chemical binding]; other site
761193011516	Mg2+ binding site [ion binding]; other site
761193011517	G-X-G motif; other site
761193011518	Surface antigen; Region: Bac_surface_Ag; pfam01103
761193011519	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193011520	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193011521	Amidohydrolase; Region: Amidohydro_4; pfam13147
761193011522	active site
761193011523	Uncharacterized copper-binding protein [Inorganic ion transport and metabolism]; Region: COG4454
761193011524	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193011525	HEAT repeats; Region: HEAT_2; pfam13646
761193011526	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193011527	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193011528	putative active site [active]
761193011529	heme pocket [chemical binding]; other site
761193011530	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193011531	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193011532	putative active site [active]
761193011533	heme pocket [chemical binding]; other site
761193011534	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193011535	putative active site [active]
761193011536	heme pocket [chemical binding]; other site
761193011537	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193011538	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193011539	dimer interface [polypeptide binding]; other site
761193011540	phosphorylation site [posttranslational modification]
761193011541	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193011542	ATP binding site [chemical binding]; other site
761193011543	Mg2+ binding site [ion binding]; other site
761193011544	G-X-G motif; other site
761193011545	COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: dfe:Dfer_4108 single-strand binding protein/primosomal replication protein N; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-strand binding protein/Primosomal replication protein n; TIGRFAM: Single-strand DNA-binding
761193011546	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
761193011547	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
761193011548	dimer interface [polypeptide binding]; other site
761193011549	ssDNA binding site [nucleotide binding]; other site
761193011550	tetramer (dimer of dimers) interface [polypeptide binding]; other site
761193011551	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193011552	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
761193011553	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
761193011554	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193011555	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
761193011556	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
761193011557	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
761193011558	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193011559	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193011560	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193011561	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193011562	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193011563	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193011564	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193011565	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
761193011566	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
761193011567	N- and C-terminal domain interface [polypeptide binding]; other site
761193011568	active site
761193011569	catalytic site [active]
761193011570	metal binding site [ion binding]; metal-binding site
761193011571	carbohydrate binding site [chemical binding]; other site
761193011572	ATP binding site [chemical binding]; other site
761193011573	Ycf48-like protein; Provisional; Region: PRK13684
761193011574	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
761193011575	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
761193011576	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
761193011577	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
761193011578	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
761193011579	homotrimer interaction site [polypeptide binding]; other site
761193011580	zinc binding site [ion binding]; other site
761193011581	CDP-binding sites; other site
761193011582	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193011583	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
761193011584	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
761193011585	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193011586	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193011587	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193011588	similar to hypothetical protein; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942:IPR006145:IPR006225; KEGG: dfe:Dfer_2578 pseudouridine synthase, RluA family; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RluC/RluD
761193011589	similar to RluA family pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; KEGG: dfe:Dfer_2010 hypothetical protein; SPTR:  uncharacterized protein
761193011590	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
761193011591	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
761193011592	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
761193011593	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
761193011594	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193011595	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193011596	Domain of unknown function (DUF4126); Region: DUF4126; pfam13548
761193011597	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193011598	AAA domain; Region: AAA_21; pfam13304
761193011599	Walker A/P-loop; other site
761193011600	ATP binding site [chemical binding]; other site
761193011601	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
761193011602	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193011603	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
761193011604	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
761193011605	ATP binding site [chemical binding]; other site
761193011606	Mg++ binding site [ion binding]; other site
761193011607	motif III; other site
761193011608	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193011609	nucleotide binding region [chemical binding]; other site
761193011610	ATP-binding site [chemical binding]; other site
761193011611	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
761193011612	metal binding site 2 [ion binding]; metal-binding site
761193011613	putative DNA binding helix; other site
761193011614	metal binding site 1 [ion binding]; metal-binding site
761193011615	dimer interface [polypeptide binding]; other site
761193011616	structural Zn2+ binding site [ion binding]; other site
761193011617	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
761193011618	MPT binding site; other site
761193011619	trimer interface [polypeptide binding]; other site
761193011620	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
761193011621	putative active cleft [active]
761193011622	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
761193011623	DNA-binding site [nucleotide binding]; DNA binding site
761193011624	RNA-binding motif; other site
761193011625	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
761193011626	ApbE family; Region: ApbE; pfam02424
761193011627	serine O-acetyltransferase; Region: cysE; TIGR01172
761193011628	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
761193011629	trimer interface [polypeptide binding]; other site
761193011630	active site
761193011631	substrate binding site [chemical binding]; other site
761193011632	CoA binding site [chemical binding]; other site
761193011633	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193011634	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193011635	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
761193011636	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
761193011637	fructokinase; Reviewed; Region: PRK09557
761193011638	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
761193011639	nucleotide binding site [chemical binding]; other site
761193011640	Glucokinase; Region: Glucokinase; cl17310
761193011641	EVE domain; Region: EVE; pfam01878
761193011642	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
761193011643	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193011644	S-adenosylmethionine binding site [chemical binding]; other site
761193011645	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011646	binding surface
761193011647	TPR motif; other site
761193011648	TPR repeat; Region: TPR_11; pfam13414
761193011649	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011650	binding surface
761193011651	TPR motif; other site
761193011652	TPR repeat; Region: TPR_11; pfam13414
761193011653	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011654	binding surface
761193011655	TPR motif; other site
761193011656	TPR repeat; Region: TPR_11; pfam13414
761193011657	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
761193011658	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
761193011659	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
761193011660	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
761193011661	active site
761193011662	dimer interface [polypeptide binding]; other site
761193011663	motif 1; other site
761193011664	motif 2; other site
761193011665	motif 3; other site
761193011666	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
761193011667	anticodon binding site; other site
761193011668	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
761193011669	active site
761193011670	dimer interface [polypeptide binding]; other site
761193011671	metal binding site [ion binding]; metal-binding site
761193011672	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
761193011673	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
761193011674	oligomerisation interface [polypeptide binding]; other site
761193011675	mobile loop; other site
761193011676	roof hairpin; other site
761193011677	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011678	binding surface
761193011679	TPR motif; other site
761193011680	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
761193011681	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
761193011682	active site
761193011683	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
761193011684	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
761193011685	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
761193011686	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
761193011687	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193011688	ATP binding site [chemical binding]; other site
761193011689	putative Mg++ binding site [ion binding]; other site
761193011690	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193011691	nucleotide binding region [chemical binding]; other site
761193011692	ATP-binding site [chemical binding]; other site
761193011693	TRCF domain; Region: TRCF; pfam03461
761193011694	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
761193011695	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
761193011696	YcxB-like protein; Region: YcxB; pfam14317
761193011697	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193011698	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
761193011699	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
761193011700	putative acyl-acceptor binding pocket; other site
761193011701	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
761193011702	phosphoglyceromutase; Provisional; Region: PRK05434
761193011703	Low molecular weight phosphatase family; Region: LMWPc; cd00115
761193011704	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
761193011705	active site
761193011706	enolase; Provisional; Region: eno; PRK00077
761193011707	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
761193011708	dimer interface [polypeptide binding]; other site
761193011709	metal binding site [ion binding]; metal-binding site
761193011710	substrate binding pocket [chemical binding]; other site
761193011711	LL-diaminopimelate aminotransferase; Provisional; Region: PRK09276
761193011712	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193011713	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193011714	homodimer interface [polypeptide binding]; other site
761193011715	catalytic residue [active]
761193011716	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_2; cd06160
761193011717	Peptidase family M50; Region: Peptidase_M50; pfam02163
761193011718	active site
761193011719	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
761193011720	putative substrate binding region [chemical binding]; other site
761193011721	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
761193011722	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193011723	motif II; other site
761193011724	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
761193011725	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
761193011726	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
761193011727	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
761193011728	Beta-Casp domain; Region: Beta-Casp; smart01027
761193011729	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
761193011730	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
761193011731	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193011732	putative DNA binding site [nucleotide binding]; other site
761193011733	putative Zn2+ binding site [ion binding]; other site
761193011734	AsnC family; Region: AsnC_trans_reg; pfam01037
761193011735	galactokinase; Provisional; Region: PRK05322
761193011736	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
761193011737	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
761193011738	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
761193011739	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
761193011740	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
761193011741	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
761193011742	active site
761193011743	1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism]; Region: Acd; COG2515
761193011744	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
761193011745	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193011746	catalytic residue [active]
761193011747	purine nucleoside phosphorylase; Provisional; Region: PRK08202
761193011748	FOG: WD40 repeat [General function prediction only]; Region: COG2319
761193011749	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
761193011750	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193011751	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011752	binding surface
761193011753	TPR motif; other site
761193011754	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011755	binding surface
761193011756	TPR motif; other site
761193011757	Outer membrane lipoprotein; Region: YfiO; pfam13525
761193011758	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011759	binding surface
761193011760	TPR motif; other site
761193011761	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
761193011762	binding surface
761193011763	TPR motif; other site
761193011764	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1729
761193011765	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
761193011766	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193011767	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DedD; COG3147
761193011768	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
761193011769	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
761193011770	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
761193011771	Methyltransferase domain; Region: Methyltransf_31; pfam13847
761193011772	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
761193011773	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
761193011774	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
761193011775	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
761193011776	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
761193011777	trimer interface [polypeptide binding]; other site
761193011778	active site
761193011779	substrate binding site [chemical binding]; other site
761193011780	CoA binding site [chemical binding]; other site
761193011781	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193011782	non-specific DNA binding site [nucleotide binding]; other site
761193011783	salt bridge; other site
761193011784	sequence-specific DNA binding site [nucleotide binding]; other site
761193011785	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011786	binding surface
761193011787	TPR motif; other site
761193011788	DNA gyrase subunit A; Validated; Region: PRK05560
761193011789	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
761193011790	CAP-like domain; other site
761193011791	active site
761193011792	primary dimer interface [polypeptide binding]; other site
761193011793	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
761193011794	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
761193011795	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
761193011796	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
761193011797	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
761193011798	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
761193011799	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
761193011800	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
761193011801	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
761193011802	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
761193011803	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
761193011804	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
761193011805	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
761193011806	LabA_like proteins; Region: LabA_like; cd06167
761193011807	putative metal binding site [ion binding]; other site
761193011808	Uncharacterized conserved protein [Function unknown]; Region: COG1432
761193011809	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
761193011810	RNA-binding motif; other site
761193011811	DNA-binding site [nucleotide binding]; DNA binding site
761193011812	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
761193011813	putative active cleft [active]
761193011814	dimerization interface [polypeptide binding]; other site
761193011815	Zinc dependent phospholipase C/S1-P1 nuclease; Region: ZnPC_S1P1; cd10981
761193011816	Zn binding site [ion binding]; other site
761193011817	Stress responsive A/B Barrel Domain; Region: Dabb; pfam07876
761193011818	putative anti-sigmaE protein; Provisional; Region: PRK13920
761193011819	Anti-sigma-K factor rskA; Region: RskA; pfam10099
761193011820	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
761193011821	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193011822	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193011823	DNA binding residues [nucleotide binding]
761193011824	PUA domain; Region: PUA; cl00607
761193011825	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
761193011826	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
761193011827	putative RNA binding site [nucleotide binding]; other site
761193011828	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193011829	S-adenosylmethionine binding site [chemical binding]; other site
761193011830	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
761193011831	active site
761193011832	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
761193011833	active site
761193011834	dimer interface [polypeptide binding]; other site
761193011835	Glutamine amidotransferase domain; Region: GATase_6; pfam13522
761193011836	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
761193011837	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193011838	Uncharacterized conserved protein [Function unknown]; Region: COG1434
761193011839	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
761193011840	putative active site [active]
761193011841	DNA topoisomerase IV subunit A; Provisional; Region: PRK12758
761193011842	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
761193011843	CAP-like domain; other site
761193011844	active site
761193011845	primary dimer interface [polypeptide binding]; other site
761193011846	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
761193011847	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
761193011848	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
761193011849	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193011850	S-adenosylmethionine binding site [chemical binding]; other site
761193011851	Predicted double-stranded RNA/RNA-DNA hybrid binding protein [General function prediction only]; Region: COG3341
761193011852	Caulimovirus viroplasmin; Region: Cauli_VI; pfam01693
761193011853	RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner; Region: RNase_H; cd06222
761193011854	active site
761193011855	RNA/DNA hybrid binding site [nucleotide binding]; other site
761193011856	Methane oxygenase PmoA; Region: PmoA; pfam14100
761193011857	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193011858	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193011859	active site
761193011860	phosphorylation site [posttranslational modification]
761193011861	intermolecular recognition site; other site
761193011862	dimerization interface [polypeptide binding]; other site
761193011863	Queuosine biosynthesis protein; Region: Queuosine_synth; pfam02547
761193011864	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
761193011865	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
761193011866	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
761193011867	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
761193011868	homodimer interface [polypeptide binding]; other site
761193011869	oligonucleotide binding site [chemical binding]; other site
761193011870	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193011871	binding surface
761193011872	TPR motif; other site
761193011873	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
761193011874	IHF - DNA interface [nucleotide binding]; other site
761193011875	IHF dimer interface [polypeptide binding]; other site
761193011876	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
761193011877	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
761193011878	minor groove reading motif; other site
761193011879	helix-hairpin-helix signature motif; other site
761193011880	substrate binding pocket [chemical binding]; other site
761193011881	active site
761193011882	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
761193011883	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
761193011884	DNA binding and oxoG recognition site [nucleotide binding]
761193011885	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
761193011886	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
761193011887	dimer interface [polypeptide binding]; other site
761193011888	ssDNA binding site [nucleotide binding]; other site
761193011889	tetramer (dimer of dimers) interface [polypeptide binding]; other site
761193011890	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193011891	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_9; cd07245
761193011892	dimer interface [polypeptide binding]; other site
761193011893	putative metal binding site [ion binding]; other site
761193011894	methionine sulfoxide reductase B; Provisional; Region: PRK00222
761193011895	SelR domain; Region: SelR; pfam01641
761193011896	tropinone reductase; Provisional; Region: PRK09242
761193011897	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193011898	NAD(P) binding site [chemical binding]; other site
761193011899	active site
761193011900	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
761193011901	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193011902	putative substrate translocation pore; other site
761193011903	Galactokinase [Carbohydrate transport and metabolism]; Region: GalK; COG0153
761193011904	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
761193011905	Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy; Region: CHS_like; cd00831
761193011906	Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BcsA; COG3424
761193011907	malonyl-CoA binding site [chemical binding]; other site
761193011908	dimer interface [polypeptide binding]; other site
761193011909	active site
761193011910	product binding site; other site
761193011911	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193011912	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193011913	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193011914	DNA binding residues [nucleotide binding]
761193011915	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
761193011916	CAAX protease self-immunity; Region: Abi; pfam02517
761193011917	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
761193011918	The enzymes of glycosyl hydrolase family 31 (GH31) occur in prokaryotes, eukaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-xylosidase, 6-alpha-glucosyltransferase; Region: GH31; cl11402
761193011919	active site
761193011920	catalytic site [active]
761193011921	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
761193011922	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
761193011923	ABC1 family; Region: ABC1; cl17513
761193011924	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
761193011925	active site
761193011926	ATP binding site [chemical binding]; other site
761193011927	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193011928	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193011929	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193011930	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
761193011931	active site
761193011932	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
761193011933	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
761193011934	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193011935	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193011936	active site
761193011937	phosphorylation site [posttranslational modification]
761193011938	intermolecular recognition site; other site
761193011939	dimerization interface [polypeptide binding]; other site
761193011940	LytTr DNA-binding domain; Region: LytTR; smart00850
761193011941	Histidine kinase; Region: His_kinase; pfam06580
761193011942	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193011943	ATP binding site [chemical binding]; other site
761193011944	Mg2+ binding site [ion binding]; other site
761193011945	G-X-G motif; other site
761193011946	Transcriptional regulator [Transcription]; Region: LysR; COG0583
761193011947	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
761193011948	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
761193011949	dimerization interface [polypeptide binding]; other site
761193011950	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
761193011951	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193011952	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193011953	homodimer interface [polypeptide binding]; other site
761193011954	catalytic residue [active]
761193011955	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
761193011956	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
761193011957	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193011958	FtsX-like permease family; Region: FtsX; pfam02687
761193011959	gliding motility-associated protein GldC; Region: GldC; TIGR03515
761193011960	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
761193011961	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
761193011962	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
761193011963	GTA TIM-barrel-like domain; Region: GTA_TIM; pfam13547
761193011964	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193011965	RNA polymerase sigma factor, cyanobacterial RpoD-like family; Region: Sig70-cyanoRpoD; TIGR02997
761193011966	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
761193011967	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193011968	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
761193011969	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193011970	DNA binding residues [nucleotide binding]
761193011971	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
761193011972	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
761193011973	RNase E interface [polypeptide binding]; other site
761193011974	trimer interface [polypeptide binding]; other site
761193011975	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
761193011976	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
761193011977	RNase E interface [polypeptide binding]; other site
761193011978	trimer interface [polypeptide binding]; other site
761193011979	active site
761193011980	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
761193011981	putative nucleic acid binding region [nucleotide binding]; other site
761193011982	G-X-X-G motif; other site
761193011983	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
761193011984	RNA binding site [nucleotide binding]; other site
761193011985	domain interface; other site
761193011986	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
761193011987	16S/18S rRNA binding site [nucleotide binding]; other site
761193011988	S13e-L30e interaction site [polypeptide binding]; other site
761193011989	25S rRNA binding site [nucleotide binding]; other site
761193011990	Predicted permeases [General function prediction only]; Region: COG0795
761193011991	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
761193011992	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
761193011993	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
761193011994	SPTR: Transposase IS4 family protein
761193011995	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
761193011996	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
761193011997	substrate binding site [chemical binding]; other site
761193011998	active site
761193011999	catalytic residues [active]
761193012000	heterodimer interface [polypeptide binding]; other site
761193012001	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
761193012002	active site
761193012003	catalytic residues [active]
761193012004	metal binding site [ion binding]; metal-binding site
761193012005	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193012006	HEAT repeats; Region: HEAT_2; pfam13646
761193012007	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
761193012008	Cytochrome c; Region: Cytochrom_C; pfam00034
761193012009	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193012010	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193012011	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
761193012012	metal binding site 2 [ion binding]; metal-binding site
761193012013	putative DNA binding helix; other site
761193012014	metal binding site 1 [ion binding]; metal-binding site
761193012015	dimer interface [polypeptide binding]; other site
761193012016	structural Zn2+ binding site [ion binding]; other site
761193012017	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
761193012018	Flavodoxin; Region: Flavodoxin_1; pfam00258
761193012019	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
761193012020	FAD binding pocket [chemical binding]; other site
761193012021	conserved FAD binding motif [chemical binding]; other site
761193012022	phosphate binding motif [ion binding]; other site
761193012023	beta-alpha-beta structure motif; other site
761193012024	NAD binding pocket [chemical binding]; other site
761193012025	Predicted periplasmic protein (DUF2271); Region: DUF2271; pfam10029
761193012026	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
761193012027	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
761193012028	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
761193012029	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
761193012030	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
761193012031	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
761193012032	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
761193012033	ApbE family; Region: ApbE; pfam02424
761193012034	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012035	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
761193012036	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
761193012037	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
761193012038	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
761193012039	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
761193012040	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193012041	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
761193012042	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193012043	N-terminal plug; other site
761193012044	ligand-binding site [chemical binding]; other site
761193012045	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
761193012046	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193012047	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
761193012048	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
761193012049	Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023
761193012050	Bacterial sugar transferase; Region: Bac_transf; pfam02397
761193012051	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193012052	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193012053	NAD(P) binding site [chemical binding]; other site
761193012054	active site
761193012055	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
761193012056	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
761193012057	Ligand binding site; other site
761193012058	Putative Catalytic site; other site
761193012059	DXD motif; other site
761193012060	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
761193012061	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
761193012062	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
761193012063	Capsule assembly protein Wzi; Region: Caps_assemb_Wzi; pfam14052
761193012064	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
761193012065	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
761193012066	NADP binding site [chemical binding]; other site
761193012067	active site
761193012068	putative substrate binding site [chemical binding]; other site
761193012069	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
761193012070	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
761193012071	substrate binding site; other site
761193012072	tetramer interface; other site
761193012073	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
761193012074	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
761193012075	NAD binding site [chemical binding]; other site
761193012076	substrate binding site [chemical binding]; other site
761193012077	homodimer interface [polypeptide binding]; other site
761193012078	active site
761193012079	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
761193012080	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193012081	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193012082	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193012083	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193012084	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
761193012085	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193012086	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
761193012087	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
761193012088	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
761193012089	active site
761193012090	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
761193012091	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
761193012092	active site
761193012093	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
761193012094	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
761193012095	trimer interface [polypeptide binding]; other site
761193012096	active site
761193012097	substrate binding site [chemical binding]; other site
761193012098	CoA binding site [chemical binding]; other site
761193012099	NeuB family; Region: NeuB; pfam03102
761193012100	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
761193012101	active site
761193012102	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
761193012103	active site
761193012104	Chain length determinant protein; Region: Wzz; cl15801
761193012105	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
761193012106	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
761193012107	exopolysaccharide/PEP-CTERM locus tyrosine autokinase; Region: pepcterm_TyrKin; TIGR03018
761193012108	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
761193012109	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
761193012110	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
761193012111	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
761193012112	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
761193012113	homotetramer interface [polypeptide binding]; other site
761193012114	ligand binding site [chemical binding]; other site
761193012115	catalytic site [active]
761193012116	NAD binding site [chemical binding]; other site
761193012117	S-adenosylmethionine synthetase; Validated; Region: PRK05250
761193012118	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
761193012119	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
761193012120	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
761193012121	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
761193012122	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
761193012123	putative active site [active]
761193012124	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
761193012125	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193012126	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193012127	Peptidase family M48; Region: Peptidase_M48; pfam01435
761193012128	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
761193012129	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
761193012130	active site
761193012131	interdomain interaction site; other site
761193012132	putative metal-binding site [ion binding]; other site
761193012133	nucleotide binding site [chemical binding]; other site
761193012134	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
761193012135	domain I; other site
761193012136	DNA binding groove [nucleotide binding]
761193012137	phosphate binding site [ion binding]; other site
761193012138	domain II; other site
761193012139	domain III; other site
761193012140	nucleotide binding site [chemical binding]; other site
761193012141	catalytic site [active]
761193012142	domain IV; other site
761193012143	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
761193012144	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
761193012145	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
761193012146	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012147	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193012148	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193012149	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
761193012150	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193012151	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193012152	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
761193012153	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
761193012154	putative Iron-sulfur protein interface [polypeptide binding]; other site
761193012155	proximal heme binding site [chemical binding]; other site
761193012156	distal heme binding site [chemical binding]; other site
761193012157	putative dimer interface [polypeptide binding]; other site
761193012158	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
761193012159	L-aspartate oxidase; Provisional; Region: PRK06175
761193012160	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
761193012161	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
761193012162	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
761193012163	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
761193012164	Fasciclin domain; Region: Fasciclin; pfam02469
761193012165	Fasciclin domain; Region: Fasciclin; pfam02469
761193012166	Histidine kinase; Region: His_kinase; pfam06580
761193012167	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193012168	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193012169	active site
761193012170	phosphorylation site [posttranslational modification]
761193012171	intermolecular recognition site; other site
761193012172	dimerization interface [polypeptide binding]; other site
761193012173	LytTr DNA-binding domain; Region: LytTR; smart00850
761193012174	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
761193012175	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
761193012176	active site
761193012177	catalytic triad [active]
761193012178	oxyanion hole [active]
761193012179	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193012180	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193012181	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193012182	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193012183	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193012184	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193012185	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193012186	active site
761193012187	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
761193012188	The Sema domain, a protein interacting module, of semaphorins and plexins; Region: Sema; cl15693
761193012189	hypothetical protein; Provisional; Region: PRK02947
761193012190	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
761193012191	putative active site [active]
761193012192	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
761193012193	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
761193012194	nucleotide binding site [chemical binding]; other site
761193012195	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
761193012196	classical (c) SDRs; Region: SDR_c; cd05233
761193012197	NAD(P) binding site [chemical binding]; other site
761193012198	active site
761193012199	Cupin domain; Region: Cupin_2; cl17218
761193012200	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193012201	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
761193012202	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
761193012203	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
761193012204	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
761193012205	dimer interface [polypeptide binding]; other site
761193012206	active site
761193012207	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
761193012208	EamA-like transporter family; Region: EamA; cl17759
761193012209	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
761193012210	EamA-like transporter family; Region: EamA; cl17759
761193012211	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
761193012212	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
761193012213	nucleotide binding site [chemical binding]; other site
761193012214	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
761193012215	Gram-negative bacterial tonB protein; Region: TonB; cl10048
761193012216	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_3; cd09620
761193012217	putative ligand binding site [chemical binding]; other site
761193012218	Predicted membrane protein [Function unknown]; Region: COG2311
761193012219	Protein of unknown function (DUF1624); Region: DUF1624; cl01394
761193012220	Protein of unknown function (DUF418); Region: DUF418; pfam04235
761193012221	COGs: COG1373 ATPase (AAA+ superfamily); InterPro IPR003593; KEGG: sli:Slin_6960 transcriptional regulator, ArsR family; SMART: ATPase, AAA+ type, core; SPTR: Transcriptional regulator, ArsR family
761193012222	NACHT domain; Region: NACHT; pfam05729
761193012223	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193012224	Walker A motif; other site
761193012225	ATP binding site [chemical binding]; other site
761193012226	Walker B motif; other site
761193012227	arginine finger; other site
761193012228	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
761193012229	Ureide permease; Region: Ureide_permease; pfam07168
761193012230	Ureide permease; Region: Ureide_permease; pfam07168
761193012231	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
761193012232	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
761193012233	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
761193012234	substrate binding site [chemical binding]; other site
761193012235	dimer interface [polypeptide binding]; other site
761193012236	ATP binding site [chemical binding]; other site
761193012237	KEGG: ote:Oter_4539 hypothetical protein; SPTR:  uncharacterized protein
761193012238	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193012239	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
761193012240	Transcriptional regulator [Transcription]; Region: IclR; COG1414
761193012241	Bacterial transcriptional regulator; Region: IclR; pfam01614
761193012242	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
761193012243	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
761193012244	putative NAD(P) binding site [chemical binding]; other site
761193012245	catalytic Zn binding site [ion binding]; other site
761193012246	structural Zn binding site [ion binding]; other site
761193012247	2-deoxy-D-gluconate 3-dehydrogenase; Region: kduD; TIGR01832
761193012248	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
761193012249	NADP binding site [chemical binding]; other site
761193012250	homodimer interface [polypeptide binding]; other site
761193012251	active site
761193012252	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193012253	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012254	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193012255	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193012256	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193012257	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193012258	SusD family; Region: SusD; pfam07980
761193012259	Glycoside hydrolase family 44; Region: Glyco_hydro_44; pfam12891
761193012260	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
761193012261	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
761193012262	Glycosyl hydrolases family 39; Region: Glyco_hydro_39; pfam01229
761193012263	Right handed beta helix region; Region: Beta_helix; pfam13229
761193012264	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193012265	Glycosyl Hydrolase Family 88; Region: Glyco_hydro_88; pfam07470
761193012266	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u1; cd11477
761193012267	Na binding site [ion binding]; other site
761193012268	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
761193012269	classical (c) SDRs; Region: SDR_c; cd05233
761193012270	NAD(P) binding site [chemical binding]; other site
761193012271	active site
761193012272	Demethylmenaquinone methyltransferase [Coenzyme metabolism]; Region: MenG; COG0684
761193012273	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193012274	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
761193012275	active site
761193012276	metal binding site [ion binding]; metal-binding site
761193012277	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
761193012278	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
761193012279	NAD(P) binding site [chemical binding]; other site
761193012280	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
761193012281	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
761193012282	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
761193012283	active site
761193012284	HIGH motif; other site
761193012285	dimer interface [polypeptide binding]; other site
761193012286	KMSKS motif; other site
761193012287	PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_4; cd03395
761193012288	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
761193012289	active site
761193012290	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
761193012291	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
761193012292	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
761193012293	active site
761193012294	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
761193012295	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
761193012296	5S rRNA interface [nucleotide binding]; other site
761193012297	CTC domain interface [polypeptide binding]; other site
761193012298	L16 interface [polypeptide binding]; other site
761193012299	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
761193012300	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193012301	catalytic residues [active]
761193012302	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193012303	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193012304	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
761193012305	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
761193012306	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
761193012307	classical (c) SDRs; Region: SDR_c; cd05233
761193012308	NAD(P) binding site [chemical binding]; other site
761193012309	active site
761193012310	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
761193012311	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
761193012312	nucleotide binding site [chemical binding]; other site
761193012313	hypothetical protein; Provisional; Region: PRK02947
761193012314	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
761193012315	putative active site [active]
761193012316	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
761193012317	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193012318	Coenzyme A binding pocket [chemical binding]; other site
761193012319	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
761193012320	substrate binding site [chemical binding]; other site
761193012321	THF binding site; other site
761193012322	zinc-binding site [ion binding]; other site
761193012323	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
761193012324	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
761193012325	Protein of unknown function DUF58; Region: DUF58; pfam01882
761193012326	COGs: COG0714 MoxR-like ATPase; InterPro IPR011703; KEGG: sli:Slin_1324 ATPase AAA; PFAM: ATPase associated with various cellular activities, AAA-3; SPTR: ATPase associated with various cellular activities AAA_3
761193012327	MoxR-like ATPases [General function prediction only]; Region: COG0714
761193012328	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193012329	Walker A motif; other site
761193012330	ATP binding site [chemical binding]; other site
761193012331	Walker B motif; other site
761193012332	arginine finger; other site
761193012333	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
761193012334	COGs: COG0312 Zn-dependent protease and their inactivated homologs; InterPro IPR002510; KEGG: sli:Slin_1334 peptidase U62 modulator of DNA gyrase; PFAM: Peptidase U62, modulator of DNA gyrase; SPTR: Peptidase U62 modulator of DNA gyrase
761193012335	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
761193012336	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
761193012337	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
761193012338	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
761193012339	Ligand binding site; other site
761193012340	metal-binding site
761193012341	similar to hypothetical protein; COGs: COG0101 Pseudouridylate synthase; HAMAP: Pseudouridine synthase I, TruA; InterPro IPR001406:IPR020097; KEGG: dfe:Dfer_2502 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; SPTR: tRNA pseudouridine synthase A; TIGRFAM: Pseudouridine synthase I, TruA
761193012342	similar to tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I; InterPro IPR000297; KEGG: sli:Slin_0807 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase
761193012343	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
761193012344	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
761193012345	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
761193012346	ligand binding site [chemical binding]; other site
761193012347	SurA N-terminal domain; Region: SurA_N; pfam09312
761193012348	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
761193012349	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
761193012350	MoxR-like ATPases [General function prediction only]; Region: COG0714
761193012351	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193012352	Walker A motif; other site
761193012353	ATP binding site [chemical binding]; other site
761193012354	Walker B motif; other site
761193012355	arginine finger; other site
761193012356	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
761193012357	Malic enzyme, N-terminal domain; Region: malic; pfam00390
761193012358	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
761193012359	putative NAD(P) binding site [chemical binding]; other site
761193012360	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
761193012361	similar to riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0130 Pseudouridine synthase; HAMAP: tRNA pseudouridine synthase B; InterPro IPR002501:IPR014780; KEGG: dfe:Dfer_1246 tRNA pseudouridine synthase B; PFAM: Pseudouridine synthase II, TruB, N-terminal; SPTR: tRNA pseudouridine synthase B; TIGRFAM: Pseudouridine synthase II, TruB, N-terminal, bacterial-type
761193012362	similar to tRNA pseudouridine synthase B; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase; COGs: COG1968 Uncharacterized bacitracin resistance protein; HAMAP: Undecaprenyl-diphosphatase; InterPro IPR003824; KEGG: psn:Pedsa_0245 undecaprenyl-diphosphatase; PFAM: Bacitracin resistance protein BacA; SPTR: Undecaprenyl-diphosphatase; TIGRFAM: Bacitracin resistance protein BacA
761193012363	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
761193012364	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
761193012365	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
761193012366	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
761193012367	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
761193012368	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
761193012369	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193012370	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
761193012371	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
761193012372	DNA-binding site [nucleotide binding]; DNA binding site
761193012373	RNA-binding motif; other site
761193012374	DNA-directed RNA polymerase subunit B; Provisional; Region: PRK08565
761193012375	HD domain; Region: HD_3; pfam13023
761193012376	Protein of unknown function (DUF2568); Region: DUF2568; pfam10823
761193012377	Protein of unknown function (DUF3037); Region: DUF3037; pfam11236
761193012378	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193012379	TPR motif; other site
761193012380	binding surface
761193012381	TPR repeat; Region: TPR_11; pfam13414
761193012382	SopA-like catalytic domain; Region: SopA_C; pfam13979
761193012383	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
761193012384	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193012385	putative substrate translocation pore; other site
761193012386	Hypothetical enzyme TM0436 resembles the zinc-dependent alcohol dehydrogenases (ADH); Region: MDR_TM0436_like; cd08231
761193012387	catalytic Zn binding site [ion binding]; other site
761193012388	putative phosphonate catabolism associated alcohol dehydrogenase; Region: HpnZ_proposed; TIGR03366
761193012389	structural Zn binding site [ion binding]; other site
761193012390	tetramer interface [polypeptide binding]; other site
761193012391	SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site...; Region: SGNH_hydrolase_like_2; cd01834
761193012392	active site
761193012393	catalytic triad [active]
761193012394	oxyanion hole [active]
761193012395	SWIM zinc finger; Region: SWIM; pfam04434
761193012396	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
761193012397	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
761193012398	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193012399	ATP binding site [chemical binding]; other site
761193012400	putative Mg++ binding site [ion binding]; other site
761193012401	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193012402	nucleotide binding region [chemical binding]; other site
761193012403	ATP-binding site [chemical binding]; other site
761193012404	SPRY domain; Region: SPRY; cl02614
761193012405	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193012406	Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; cl01472
761193012407	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
761193012408	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193012409	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193012410	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193012411	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193012412	Predicted membrane protein [Function unknown]; Region: COG2860
761193012413	UPF0126 domain; Region: UPF0126; pfam03458
761193012414	UPF0126 domain; Region: UPF0126; pfam03458
761193012415	bile acid transporter; Region: bass; TIGR00841
761193012416	Sodium Bile acid symporter family; Region: SBF; cl17470
761193012417	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
761193012418	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Region: LPLAT_AAK14816-like; cd07992
761193012419	putative acyl-acceptor binding pocket; other site
761193012420	COGs: COG1526 Uncharacterized protein required for formate dehydrogenase activity; HAMAP: Protein fdhD; InterPro IPR003786; KEGG: dfe:Dfer_2665 formate dehydrogenase accessory protein FdhD; PFAM: Formate dehydrogenase, subunit FdhD; SPTR: Protein FdhD homolog; TIGRFAM: Formate dehydrogenase, subunit FdhD
761193012421	FdhD/NarQ family; Region: FdhD-NarQ; cl00659
761193012422	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193012423	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193012424	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193012425	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193012426	NADH(P)-binding; Region: NAD_binding_10; pfam13460
761193012427	NAD(P) binding site [chemical binding]; other site
761193012428	active site
761193012429	Histidine kinase; Region: His_kinase; pfam06580
761193012430	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193012431	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193012432	active site
761193012433	phosphorylation site [posttranslational modification]
761193012434	intermolecular recognition site; other site
761193012435	dimerization interface [polypeptide binding]; other site
761193012436	LytTr DNA-binding domain; Region: LytTR; smart00850
761193012437	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193012438	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
761193012439	oligomerisation interface [polypeptide binding]; other site
761193012440	mobile loop; other site
761193012441	roof hairpin; other site
761193012442	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
761193012443	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
761193012444	ring oligomerisation interface [polypeptide binding]; other site
761193012445	ATP/Mg binding site [chemical binding]; other site
761193012446	stacking interactions; other site
761193012447	hinge regions; other site
761193012448	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
761193012449	Found in ATP-dependent protease La (LON); Region: LON; smart00464
761193012450	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193012451	Walker A motif; other site
761193012452	ATP binding site [chemical binding]; other site
761193012453	Walker B motif; other site
761193012454	arginine finger; other site
761193012455	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
761193012456	aminotransferase AlaT; Validated; Region: PRK09265
761193012457	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193012458	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193012459	homodimer interface [polypeptide binding]; other site
761193012460	catalytic residue [active]
761193012461	Domain of unknown function (DUF4290); Region: DUF4290; pfam14123
761193012462	Glycosyltransferase like family; Region: Glyco_tranf_2_5; pfam13712
761193012463	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
761193012464	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
761193012465	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
761193012466	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
761193012467	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
761193012468	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
761193012469	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
761193012470	substrate binding pocket [chemical binding]; other site
761193012471	catalytic triad [active]
761193012472	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
761193012473	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
761193012474	Uncharacterized hypothetical proteins similar to the catalytic domains of Phosphoinositide-specific phospholipaseand Glycerophosphodiester phosphodiesterases; Region: PI-PLCc_GDPD_SF_unchar3; cd08577
761193012475	putative active site [active]
761193012476	catalytic site [active]
761193012477	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
761193012478	dimer interface [polypeptide binding]; other site
761193012479	Alkaline phosphatase homologues; Region: alkPPc; smart00098
761193012480	active site
761193012481	integral membrane protein; Region: integ_memb_HG; TIGR03954
761193012482	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
761193012483	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
761193012484	Transglycosylase; Region: Transgly; pfam00912
761193012485	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
761193012486	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
761193012487	TPR repeat; Region: TPR_11; pfam13414
761193012488	binding surface
761193012489	TPR motif; other site
761193012490	Methyltransferase domain; Region: Methyltransf_31; pfam13847
761193012491	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193012492	S-adenosylmethionine binding site [chemical binding]; other site
761193012493	Protein of unknown function (DUF2452); Region: DUF2452; pfam10504
761193012494	Phage shock protein B; Region: PspB; cl05946
761193012495	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012496	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
761193012497	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193012498	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193012499	homodimer interface [polypeptide binding]; other site
761193012500	catalytic residue [active]
761193012501	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
761193012502	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193012503	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193012504	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012505	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193012506	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193012507	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193012508	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
761193012509	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193012510	homodimer interface [polypeptide binding]; other site
761193012511	catalytic residue [active]
761193012512	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cl17442
761193012513	SurA N-terminal domain; Region: SurA_N_3; cl07813
761193012514	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
761193012515	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
761193012516	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193012517	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193012518	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
761193012519	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
761193012520	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
761193012521	proposed catalytic triad [active]
761193012522	active site nucleophile [active]
761193012523	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
761193012524	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
761193012525	active site
761193012526	substrate binding site [chemical binding]; other site
761193012527	Mg2+ binding site [ion binding]; other site
761193012528	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
761193012529	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193012530	non-specific DNA binding site [nucleotide binding]; other site
761193012531	salt bridge; other site
761193012532	sequence-specific DNA binding site [nucleotide binding]; other site
761193012533	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
761193012534	D5 N terminal like; Region: D5_N; pfam08706
761193012535	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
761193012536	Helix-turn-helix domain; Region: HTH_17; pfam12728
761193012537	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
761193012538	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
761193012539	Int/Topo IB signature motif; other site
761193012540	Helix-turn-helix domain; Region: HTH_17; pfam12728
761193012541	Helix-turn-helix domain; Region: HTH_17; pfam12728
761193012542	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
761193012543	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
761193012544	trmE is a tRNA modification GTPase; Region: trmE; cd04164
761193012545	G1 box; other site
761193012546	GTP/Mg2+ binding site [chemical binding]; other site
761193012547	Switch I region; other site
761193012548	G2 box; other site
761193012549	Switch II region; other site
761193012550	G3 box; other site
761193012551	G4 box; other site
761193012552	G5 box; other site
761193012553	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
761193012554	Domain of unknown function (DUF4177); Region: DUF4177; pfam13783
761193012555	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
761193012556	Uncharacterized conserved protein [Function unknown]; Region: COG5276
761193012557	Uncharacterized conserved protein [Function unknown]; Region: COG5276
761193012558	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193012559	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193012560	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193012561	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193012562	ligand binding site [chemical binding]; other site
761193012563	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
761193012564	Putative collagen-binding domain of a collagenase; Region: Collagen_bind_2; pfam12904
761193012565	2-oxoglutarate ferredoxin oxidoreductase subunit beta; Validated; Region: PRK05778
761193012566	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
761193012567	TPP-binding site [chemical binding]; other site
761193012568	Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Region: PFO_beta_C; pfam12367
761193012569	Fic family protein [Function unknown]; Region: COG3177
761193012570	Domain of unknown function (DUF4172); Region: DUF4172; pfam13776
761193012571	Fic/DOC family; Region: Fic; pfam02661
761193012572	2-oxoacid:acceptor oxidoreductase, alpha subunit; Region: OAFO_sf; TIGR03710
761193012573	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
761193012574	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
761193012575	dimer interface [polypeptide binding]; other site
761193012576	PYR/PP interface [polypeptide binding]; other site
761193012577	TPP binding site [chemical binding]; other site
761193012578	substrate binding site [chemical binding]; other site
761193012579	putative glutamate synthase (NADPH) small subunit; Provisional; Region: PRK12771
761193012580	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193012581	4Fe-4S binding domain; Region: Fer4; pfam00037
761193012582	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
761193012583	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
761193012584	active site
761193012585	catalytic site [active]
761193012586	Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]; Region: SKN1; COG2273
761193012587	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
761193012588	active site
761193012589	catalytic residues [active]
761193012590	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
761193012591	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193012592	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
761193012593	DNA binding residues [nucleotide binding]
761193012594	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
761193012595	FecR protein; Region: FecR; pfam04773
761193012596	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193012597	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012598	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193012599	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193012600	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193012601	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193012602	SusD family; Region: SusD; pfam07980
761193012603	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193012604	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
761193012605	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
761193012606	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
761193012607	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
761193012608	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193012609	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193012610	SusD family; Region: SusD; pfam07980
761193012611	Secretin and TonB N terminus short domain; Region: STN; pfam07660
761193012612	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193012613	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012614	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193012615	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193012616	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
761193012617	FecR protein; Region: FecR; pfam04773
761193012618	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
761193012619	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193012620	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
761193012621	DNA binding residues [nucleotide binding]
761193012622	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
761193012623	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193012624	DNA binding residues [nucleotide binding]
761193012625	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
761193012626	FecR protein; Region: FecR; pfam04773
761193012627	Secretin and TonB N terminus short domain; Region: STN; pfam07660
761193012628	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193012629	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012630	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193012631	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193012632	SusD family; Region: SusD; pfam07980
761193012633	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193012634	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193012635	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193012636	DNA binding residues [nucleotide binding]
761193012637	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
761193012638	FecR protein; Region: FecR; pfam04773
761193012639	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193012640	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012641	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193012642	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
761193012643	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193012644	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193012645	SusD family; Region: SusD; pfam07980
761193012646	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193012647	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193012648	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193012649	TRAM domain; Region: TRAM; pfam01938
761193012650	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
761193012651	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193012652	S-adenosylmethionine binding site [chemical binding]; other site
761193012653	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193012654	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
761193012655	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193012656	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
761193012657	classical (c) SDRs; Region: SDR_c; cd05233
761193012658	NAD(P) binding site [chemical binding]; other site
761193012659	active site
761193012660	putative carboxyl-terminal-processing protease, deltaproteobacterial; Region: prc_long_Delta; TIGR03900
761193012661	CHRD domain; Region: CHRD; pfam07452
761193012662	aconitate hydratase, mitochondrial; Region: aconitase_mito; TIGR01340
761193012663	Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Mitochondrial; cd01584
761193012664	substrate binding site [chemical binding]; other site
761193012665	ligand binding site [chemical binding]; other site
761193012666	Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes...; Region: AcnA_Mitochon_Swivel; cd01578
761193012667	substrate binding site [chemical binding]; other site
761193012668	Gemmata obscuriglobus paralogous family TIGR03066; Region: Gem_osc_para_1
761193012669	Sulfatase; Region: Sulfatase; cl17466
761193012670	polyphosphate kinase; Provisional; Region: PRK05443
761193012671	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
761193012672	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
761193012673	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
761193012674	putative domain interface [polypeptide binding]; other site
761193012675	putative active site [active]
761193012676	catalytic site [active]
761193012677	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
761193012678	putative domain interface [polypeptide binding]; other site
761193012679	putative active site [active]
761193012680	catalytic site [active]
761193012681	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
761193012682	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193012683	ATP binding site [chemical binding]; other site
761193012684	Mg2+ binding site [ion binding]; other site
761193012685	G-X-G motif; other site
761193012686	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
761193012687	anchoring element; other site
761193012688	dimer interface [polypeptide binding]; other site
761193012689	ATP binding site [chemical binding]; other site
761193012690	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
761193012691	active site
761193012692	putative metal-binding site [ion binding]; other site
761193012693	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
761193012694	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193012695	binding surface
761193012696	TPR motif; other site
761193012697	Family description; Region: VCBS; pfam13517
761193012698	Family description; Region: VCBS; pfam13517
761193012699	Family description; Region: VCBS; pfam13517
761193012700	Family description; Region: VCBS; pfam13517
761193012701	Family description; Region: VCBS; pfam13517
761193012702	Family description; Region: VCBS; pfam13517
761193012703	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
761193012704	Family description; Region: VCBS; pfam13517
761193012705	Family description; Region: VCBS; pfam13517
761193012706	Family description; Region: VCBS; pfam13517
761193012707	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
761193012708	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193012709	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193012710	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193012711	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193012712	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193012713	COGs: COG2355 Zn-dependent dipeptidase microsomal dipeptidase homolog; InterPro IPR008257; KEGG: sli:Slin_3958 peptidase M19 renal dipeptidase; PFAM: Peptidase M19, renal dipeptidase; SPTR: Peptidase M19 renal dipeptidase
761193012714	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
761193012715	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193012716	active site
761193012717	Uncharacterized conserved protein [Function unknown]; Region: COG4850
761193012718	Uncharacterized conserved protein (DUF2183); Region: DUF2183; pfam09949
761193012719	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
761193012720	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
761193012721	Diacylglycerol kinase accessory domain; Region: DAGK_acc; cl02440
761193012722	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
761193012723	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
761193012724	hexamer interface [polypeptide binding]; other site
761193012725	ligand binding site [chemical binding]; other site
761193012726	putative active site [active]
761193012727	NAD(P) binding site [chemical binding]; other site
761193012728	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
761193012729	putative oxidoreductase; Provisional; Region: PRK11579
761193012730	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193012731	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193012732	Protein of unknown function (DUF3570); Region: DUF3570; pfam12094
761193012733	glucose-1-dehydrogenase; Provisional; Region: PRK08936
761193012734	glucose 1 dehydrogenase (GlcDH), classical (c) SDRs; Region: GlcDH_SDR_c; cd05358
761193012735	NAD binding site [chemical binding]; other site
761193012736	homodimer interface [polypeptide binding]; other site
761193012737	active site
761193012738	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193012739	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
761193012740	DNA binding residues [nucleotide binding]
761193012741	dimerization interface [polypeptide binding]; other site
761193012742	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
761193012743	Predicted transcriptional regulator [Transcription]; Region: COG2378
761193012744	WYL domain; Region: WYL; pfam13280
761193012745	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cl11443
761193012746	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
761193012747	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
761193012748	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
761193012749	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
761193012750	Homeodomain-like domain; Region: HTH_23; pfam13384
761193012751	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193012752	Homeodomain-like domain; Region: HTH_32; pfam13565
761193012753	Winged helix-turn helix; Region: HTH_33; pfam13592
761193012754	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193012755	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193012756	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I; cl00803
761193012757	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
761193012758	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
761193012759	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193012760	Walker A motif; other site
761193012761	ATP binding site [chemical binding]; other site
761193012762	Walker B motif; other site
761193012763	arginine finger; other site
761193012764	Firmicute plasmid replication protein (RepL); Region: RepL; pfam05732
761193012765	Domain of unknown function DUF83; Region: Cas_Cas4; pfam01930
761193012766	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-B; cd09722
761193012767	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
761193012768	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193012769	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193012770	non-specific DNA binding site [nucleotide binding]; other site
761193012771	salt bridge; other site
761193012772	sequence-specific DNA binding site [nucleotide binding]; other site
761193012773	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
761193012774	Catalytic site [active]
761193012775	YopX protein; Region: YopX; cl09859
761193012776	L-Lactate 2-monooxygenase (LMO) FMN-binding domain. LMO is a FMN-containing enzyme that catalyzes the conversion of L-lactate and oxygen to acetate, carbon dioxide, and water. LMO is a member of the family of alpha-hydroxy acid oxidases.  It is thought...; Region: LMO_FMN; cd03332
761193012777	glycolate oxidase; Region: PLN02535
761193012778	putative active site [active]
761193012779	putative substrate binding site [chemical binding]; other site
761193012780	putative FMN binding site [chemical binding]; other site
761193012781	putative catalytic residues [active]
761193012782	Protein of unknown function (DUF962); Region: DUF962; cl01879
761193012783	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
761193012784	active site
761193012785	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193012786	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
761193012787	NAD(P) binding site [chemical binding]; other site
761193012788	active site
761193012789	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
761193012790	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
761193012791	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193012792	Cytochrome c; Region: Cytochrom_C; pfam00034
761193012793	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
761193012794	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
761193012795	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
761193012796	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
761193012797	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
761193012798	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
761193012799	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
761193012800	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
761193012801	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
761193012802	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
761193012803	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
761193012804	dimer interface [polypeptide binding]; other site
761193012805	ADP-ribose binding site [chemical binding]; other site
761193012806	active site
761193012807	nudix motif; other site
761193012808	metal binding site [ion binding]; metal-binding site
761193012809	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
761193012810	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
761193012811	DEAD-like helicases superfamily; Region: DEXDc; smart00487
761193012812	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193012813	ATP binding site [chemical binding]; other site
761193012814	putative Mg++ binding site [ion binding]; other site
761193012815	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193012816	nucleotide binding region [chemical binding]; other site
761193012817	ATP-binding site [chemical binding]; other site
761193012818	Smr domain; Region: Smr; pfam01713
761193012819	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
761193012820	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
761193012821	nucleotide binding site [chemical binding]; other site
761193012822	NEF interaction site [polypeptide binding]; other site
761193012823	SBD interface [polypeptide binding]; other site
761193012824	Uncharacterized small protein (DUF2158); Region: DUF2158; pfam09926
761193012825	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
761193012826	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
761193012827	conserved cys residue [active]
761193012828	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193012829	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193012830	ligand binding site [chemical binding]; other site
761193012831	flexible hinge region; other site
761193012832	DinB superfamily; Region: DinB_2; pfam12867
761193012833	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
761193012834	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
761193012835	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
761193012836	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
761193012837	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
761193012838	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
761193012839	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
761193012840	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
761193012841	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
761193012842	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
761193012843	RNA binding site [nucleotide binding]; other site
761193012844	Phosphotransferase enzyme family; Region: APH; pfam01636
761193012845	Predicted kinase [General function prediction only]; Region: COG4857; cl17281
761193012846	DNA primase, catalytic core; Region: dnaG; TIGR01391
761193012847	CHC2 zinc finger; Region: zf-CHC2; pfam01807
761193012848	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
761193012849	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
761193012850	active site
761193012851	metal binding site [ion binding]; metal-binding site
761193012852	interdomain interaction site; other site
761193012853	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
761193012854	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
761193012855	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
761193012856	active site
761193012857	dimer interface [polypeptide binding]; other site
761193012858	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
761193012859	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
761193012860	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
761193012861	Transposase, Mutator family; Region: Transposase_mut; pfam00872
761193012862	MULE transposase domain; Region: MULE; pfam10551
761193012863	Uncharacterized conserved protein [Function unknown]; Region: COG2433
761193012864	Homeodomain-like domain; Region: HTH_23; pfam13384
761193012865	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193012866	Homeodomain-like domain; Region: HTH_32; pfam13565
761193012867	Winged helix-turn helix; Region: HTH_33; pfam13592
761193012868	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193012869	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193012870	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193012871	D-galactonate transporter; Region: 2A0114; TIGR00893
761193012872	putative substrate translocation pore; other site
761193012873	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
761193012874	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
761193012875	active site
761193012876	intersubunit interface [polypeptide binding]; other site
761193012877	catalytic residue [active]
761193012878	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
761193012879	Trp docking motif [polypeptide binding]; other site
761193012880	putative active site [active]
761193012881	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193012882	Cytochrome c; Region: Cytochrom_C; pfam00034
761193012883	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
761193012884	Domain of unknown function (DUF4380); Region: DUF4380; pfam14315
761193012885	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
761193012886	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193012887	active site pocket [active]
761193012888	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
761193012889	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
761193012890	metal binding site [ion binding]; metal-binding site
761193012891	substrate binding pocket [chemical binding]; other site
761193012892	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
761193012893	dimer interface [polypeptide binding]; other site
761193012894	FMN binding site [chemical binding]; other site
761193012895	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
761193012896	phosphate binding site [ion binding]; other site
761193012897	Domain of unknown function DUF11; Region: DUF11; cl17728
761193012898	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193012899	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193012900	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
761193012901	Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379
761193012902	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
761193012903	Predicted proteasome-type protease [Posttranslational modification, protein turnover, chaperones]; Region: COG3484
761193012904	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193012905	active site
761193012906	A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168
761193012907	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2307
761193012908	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
761193012909	active site
761193012910	catalytic residues [active]
761193012911	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
761193012912	DEAD-like helicases superfamily; Region: DEXDc; smart00487
761193012913	ATP binding site [chemical binding]; other site
761193012914	Mg++ binding site [ion binding]; other site
761193012915	motif III; other site
761193012916	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193012917	nucleotide binding region [chemical binding]; other site
761193012918	ATP-binding site [chemical binding]; other site
761193012919	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193012920	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193012921	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
761193012922	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193012923	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
761193012924	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
761193012925	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
761193012926	META domain; Region: META; pfam03724
761193012927	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
761193012928	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
761193012929	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
761193012930	active site
761193012931	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
761193012932	homodimer interface [polypeptide binding]; other site
761193012933	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
761193012934	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193012935	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
761193012936	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
761193012937	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
761193012938	active site
761193012939	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
761193012940	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
761193012941	dimer interface [polypeptide binding]; other site
761193012942	ssDNA binding site [nucleotide binding]; other site
761193012943	tetramer (dimer of dimers) interface [polypeptide binding]; other site
761193012944	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
761193012945	integron integrase; Region: integrase_gron; TIGR02249
761193012946	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
761193012947	Int/Topo IB signature motif; other site
761193012948	Domain of unknown function (DUF4287); Region: DUF4287; pfam14117
761193012949	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
761193012950	putative hydrophobic ligand binding site [chemical binding]; other site
761193012951	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193012952	dimerization interface [polypeptide binding]; other site
761193012953	putative DNA binding site [nucleotide binding]; other site
761193012954	putative Zn2+ binding site [ion binding]; other site
761193012955	InterPro IPR000601; KEGG: lby:Lbys_2619 pkd domain containing protein; PFAM: PKD; SMART: PKD; SPTR: PKD domain containing protein
761193012956	PKD domain; Region: PKD; pfam00801
761193012957	Uncharacterized protein family (UPF0236); Region: UPF0236; pfam06782
761193012958	KEGG: sli:Slin_5068 acyltransferase; SPTR: Acyltransferase
761193012959	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
761193012960	Acyltransferase family; Region: Acyl_transf_3; pfam01757
761193012961	Protoglobin; Region: Protoglobin; pfam11563
761193012962	Domain of unknown function (DUF2024); Region: DUF2024; pfam09630
761193012963	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
761193012964	InterPro IPR003346; KEGG: sli:Slin_6004 transposase IS116/IS110/IS902 family protein; PFAM: Transposase, IS116/IS110/IS902; SPTR: Transposase IS116/IS110/IS902 family protein
761193012965	Transposase; Region: DEDD_Tnp_IS110; pfam01548
761193012966	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
761193012967	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
761193012968	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
761193012969	active site
761193012970	Int/Topo IB signature motif; other site
761193012971	DNA binding site [nucleotide binding]
761193012972	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193012973	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193012974	ligand binding site [chemical binding]; other site
761193012975	flexible hinge region; other site
761193012976	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193012977	NmrA-like family; Region: NmrA; pfam05368
761193012978	NAD(P) binding site [chemical binding]; other site
761193012979	active site
761193012980	Homeodomain-like domain; Region: HTH_23; pfam13384
761193012981	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193012982	Homeodomain-like domain; Region: HTH_32; pfam13565
761193012983	Winged helix-turn helix; Region: HTH_33; pfam13592
761193012984	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193012985	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193012986	COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: dfe:Dfer_5568  transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding; SPTR:  transcriptional regulator, Crp/Fnr family
761193012987	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193012988	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193012989	ligand binding site [chemical binding]; other site
761193012990	flexible hinge region; other site
761193012991	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
761193012992	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
761193012993	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
761193012994	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
761193012995	FAD binding pocket [chemical binding]; other site
761193012996	FAD binding motif [chemical binding]; other site
761193012997	phosphate binding motif [ion binding]; other site
761193012998	beta-alpha-beta structure motif; other site
761193012999	NAD(p) ribose binding residues [chemical binding]; other site
761193013000	NAD binding pocket [chemical binding]; other site
761193013001	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
761193013002	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193013003	catalytic loop [active]
761193013004	iron binding site [ion binding]; other site
761193013005	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193013006	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193013007	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193013008	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
761193013009	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
761193013010	hydrophobic ligand binding site; other site
761193013011	InterPro IPR011659; KEGG: cly:Celly_1776 hypothetical protein; SPTR: WD40-like beta propeller repeat protein
761193013012	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
761193013013	InterPro IPR002559; KEGG: app:CAP2UW1_1881 transposase IS4 family protein; PFAM: Transposase, IS4-like; SPTR: Transposase IS4 family protein
761193013014	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
761193013015	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
761193013016	Protein of unknown function (DUF808); Region: DUF808; cl01002
761193013017	dihydroorotase; Reviewed; Region: PRK09236
761193013018	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193013019	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
761193013020	active site
761193013021	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
761193013022	Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_14; cd12179
761193013023	putative ligand binding site [chemical binding]; other site
761193013024	putative NAD binding site [chemical binding]; other site
761193013025	catalytic site [active]
761193013026	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
761193013027	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
761193013028	COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551; KEGG: dfe:Dfer_0417 hypothetical protein; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732; SPTR:  uncharacterized protein
761193013029	hypothetical protein; Provisional; Region: PRK11820
761193013030	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
761193013031	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
761193013032	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK09260
761193013033	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
761193013034	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
761193013035	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193013036	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193013037	putative active site [active]
761193013038	heme pocket [chemical binding]; other site
761193013039	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193013040	putative active site [active]
761193013041	heme pocket [chemical binding]; other site
761193013042	GAF domain; Region: GAF_2; pfam13185
761193013043	GAF domain; Region: GAF_3; pfam13492
761193013044	PAS domain S-box; Region: sensory_box; TIGR00229
761193013045	PAS domain S-box; Region: sensory_box; TIGR00229
761193013046	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193013047	putative active site [active]
761193013048	heme pocket [chemical binding]; other site
761193013049	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193013050	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193013051	dimer interface [polypeptide binding]; other site
761193013052	phosphorylation site [posttranslational modification]
761193013053	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193013054	ATP binding site [chemical binding]; other site
761193013055	Mg2+ binding site [ion binding]; other site
761193013056	G-X-G motif; other site
761193013057	Response regulator receiver domain; Region: Response_reg; pfam00072
761193013058	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193013059	active site
761193013060	phosphorylation site [posttranslational modification]
761193013061	intermolecular recognition site; other site
761193013062	dimerization interface [polypeptide binding]; other site
761193013063	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
761193013064	putative binding surface; other site
761193013065	active site
761193013066	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
761193013067	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193013068	S-adenosylmethionine binding site [chemical binding]; other site
761193013069	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
761193013070	MgtE intracellular N domain; Region: MgtE_N; pfam03448
761193013071	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
761193013072	Divalent cation transporter; Region: MgtE; pfam01769
761193013073	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
761193013074	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
761193013075	cofactor binding site; other site
761193013076	DNA binding site [nucleotide binding]
761193013077	substrate interaction site [chemical binding]; other site
761193013078	BsuBI/PstI restriction endonuclease C-terminus; Region: BsuBI_PstI_RE; pfam06616
761193013079	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193013080	NmrA-like family; Region: NmrA; pfam05368
761193013081	NAD(P) binding site [chemical binding]; other site
761193013082	active site
761193013083	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193013084	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
761193013085	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
761193013086	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
761193013087	putative DNA binding site [nucleotide binding]; other site
761193013088	putative Zn2+ binding site [ion binding]; other site
761193013089	AsnC family; Region: AsnC_trans_reg; pfam01037
761193013090	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
761193013091	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193013092	NAD(P) binding site [chemical binding]; other site
761193013093	active site
761193013094	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
761193013095	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
761193013096	substrate-cofactor binding pocket; other site
761193013097	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193013098	catalytic residue [active]
761193013099	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
761193013100	Sulfatase; Region: Sulfatase; pfam00884
761193013101	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
761193013102	putative active site [active]
761193013103	dimerization interface [polypeptide binding]; other site
761193013104	putative tRNAtyr binding site [nucleotide binding]; other site
761193013105	PHP domain; Region: PHP; pfam02811
761193013106	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
761193013107	active site
761193013108	DNA binding site [nucleotide binding]
761193013109	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
761193013110	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
761193013111	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193013112	ATP binding site [chemical binding]; other site
761193013113	putative Mg++ binding site [ion binding]; other site
761193013114	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
761193013115	nucleotide binding region [chemical binding]; other site
761193013116	ATP-binding site [chemical binding]; other site
761193013117	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
761193013118	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193013119	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193013120	aspartate aminotransferase; Provisional; Region: PRK05764
761193013121	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
761193013122	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193013123	homodimer interface [polypeptide binding]; other site
761193013124	catalytic residue [active]
761193013125	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
761193013126	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
761193013127	DNA binding site [nucleotide binding]
761193013128	active site
761193013129	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
761193013130	Fasciclin domain; Region: Fasciclin; pfam02469
761193013131	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193013132	Domain of unknown function DUF11; Region: DUF11; pfam01345
761193013133	Thrombospondin type 3 repeat; Region: TSP_3; pfam02412
761193013134	CshA-type fibril repeat; Region: CshA_fibril_rpt; TIGR04225
761193013135	CshA-type fibril repeat; Region: CshA_fibril_rpt; TIGR04225
761193013136	C1q domain; Region: C1q; cl17543
761193013137	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
761193013138	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193013139	active site
761193013140	phosphorylation site [posttranslational modification]
761193013141	intermolecular recognition site; other site
761193013142	dimerization interface [polypeptide binding]; other site
761193013143	LytTr DNA-binding domain; Region: LytTR; smart00850
761193013144	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
761193013145	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193013146	ATP binding site [chemical binding]; other site
761193013147	Mg2+ binding site [ion binding]; other site
761193013148	G-X-G motif; other site
761193013149	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
761193013150	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193013151	ATP binding site [chemical binding]; other site
761193013152	Mg2+ binding site [ion binding]; other site
761193013153	G-X-G motif; other site
761193013154	Prokaryotic phenylalanine-4-hydroxylase (pro_PheOH); a member of the biopterin-dependent aromatic amino acid hydroxylase family of non-heme, iron(II)-dependent enzymes that also includes the eukaryotic proteins, phenylalanine-4-hydroxylase (eu_PheOH); Region: pro_PheOH; cd03348
761193013155	cofactor binding site; other site
761193013156	metal binding site [ion binding]; metal-binding site
761193013157	4-hydroxyphenylpyruvate dioxygenase; Region: 4HPPD; TIGR01263
761193013158	N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342
761193013159	dimer interface [polypeptide binding]; other site
761193013160	C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250
761193013161	active site
761193013162	Fe binding site [ion binding]; other site
761193013163	similar to acetoacetyl-CoA synthase; PFAM: AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR000748:IPR006145; KEGG: dfe:Dfer_3919 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F
761193013164	similar to pseudouridine synthase Rsu; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: amu:Amuc_0637 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR:  glycosyl transferase
761193013165	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
761193013166	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
761193013167	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
761193013168	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193013169	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
761193013170	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
761193013171	N-terminal plug; other site
761193013172	ligand-binding site [chemical binding]; other site
761193013173	Glycosyl transferase family 11; Region: Glyco_transf_11; pfam01531
761193013174	Alpha-1,2-fucosyltransferase; Region: Fut1_Fut2_like; cd11301
761193013175	GDP-Fucose binding site [chemical binding]; other site
761193013176	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193013177	Cytochrome c; Region: Cytochrom_C; pfam00034
761193013178	NIPSNAP; Region: NIPSNAP; pfam07978
761193013179	NIPSNAP; Region: NIPSNAP; pfam07978
761193013180	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
761193013181	Glycerophosphodiester phosphodiesterase domain of Agrobacterium tumefaciens and similar proteins; Region: GDPD_AtGDE_like; cd08566
761193013182	putative active site [active]
761193013183	catalytic site [active]
761193013184	putative metal binding site [ion binding]; other site
761193013185	oligomer interface [polypeptide binding]; other site
761193013186	Domain of unknown function (DUF4174); Region: DUF4174; pfam13778
761193013187	CAAX protease self-immunity; Region: Abi; pfam02517
761193013188	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
761193013189	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
761193013190	CAAX protease self-immunity; Region: Abi; pfam02517
761193013191	TIGR03503 family protein; Region: TIGR03503
761193013192	Homeodomain-like domain; Region: HTH_23; pfam13384
761193013193	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193013194	Homeodomain-like domain; Region: HTH_32; pfam13565
761193013195	Winged helix-turn helix; Region: HTH_33; pfam13592
761193013196	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193013197	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193013198	InterPro IPR000182; KEGG: sli:Slin_3211 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase
761193013199	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193013200	Coenzyme A binding pocket [chemical binding]; other site
761193013201	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
761193013202	NADH(P)-binding; Region: NAD_binding_10; pfam13460
761193013203	NAD binding site [chemical binding]; other site
761193013204	active site
761193013205	MgtC family; Region: MgtC; pfam02308
761193013206	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
761193013207	proline aminopeptidase P II; Provisional; Region: PRK10879
761193013208	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
761193013209	active site
761193013210	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
761193013211	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
761193013212	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
761193013213	active site
761193013214	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
761193013215	active site
761193013216	catalytic residues [active]
761193013217	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
761193013218	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
761193013219	active site
761193013220	NTP binding site [chemical binding]; other site
761193013221	metal binding triad [ion binding]; metal-binding site
761193013222	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
761193013223	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
761193013224	Zn2+ binding site [ion binding]; other site
761193013225	Mg2+ binding site [ion binding]; other site
761193013226	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
761193013227	Protein of unknown function (DUF2480); Region: DUF2480; pfam10652
761193013228	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
761193013229	active site
761193013230	catalytic residues [active]
761193013231	metal binding site [ion binding]; metal-binding site
761193013232	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
761193013233	MoaE interaction surface [polypeptide binding]; other site
761193013234	MoeB interaction surface [polypeptide binding]; other site
761193013235	thiocarboxylated glycine; other site
761193013236	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
761193013237	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
761193013238	Walker A motif; other site
761193013239	ATP binding site [chemical binding]; other site
761193013240	Walker B motif; other site
761193013241	arginine finger; other site
761193013242	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
761193013243	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
761193013244	conserved cys residue [active]
761193013245	LytTr DNA-binding domain; Region: LytTR; smart00850
761193013246	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
761193013247	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
761193013248	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193013249	binding surface
761193013250	TPR motif; other site
761193013251	Tetratricopeptide repeat; Region: TPR_9; pfam13371
761193013252	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193013253	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193013254	binding surface
761193013255	TPR motif; other site
761193013256	TPR repeat; Region: TPR_11; pfam13414
761193013257	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193013258	binding surface
761193013259	TPR motif; other site
761193013260	TPR repeat; Region: TPR_11; pfam13414
761193013261	TPR repeat; Region: TPR_11; pfam13414
761193013262	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193013263	binding surface
761193013264	TPR motif; other site
761193013265	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193013266	binding surface
761193013267	TPR motif; other site
761193013268	TPR repeat; Region: TPR_11; pfam13414
761193013269	Cyclomaltodextrinase, N-terminal; Region: Cyc-maltodext_N; pfam09087
761193013270	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like_3; cd11340
761193013271	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
761193013272	Ca binding site [ion binding]; other site
761193013273	active site
761193013274	homodimer interface [polypeptide binding]; other site
761193013275	catalytic site [active]
761193013276	Cyclo-malto-dextrinase C-terminal domain; Region: Cyc-maltodext_C; pfam10438
761193013277	Cupin domain; Region: Cupin_2; cl17218
761193013278	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193013279	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193013280	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C); Region: NT5C; cl17836
761193013281	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
761193013282	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193013283	motif II; other site
761193013284	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
761193013285	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193013286	putative metal binding site [ion binding]; other site
761193013287	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193013288	putative substrate translocation pore; other site
761193013289	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193013290	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193013291	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
761193013292	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
761193013293	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
761193013294	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
761193013295	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
761193013296	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
761193013297	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
761193013298	PGAP1-like protein; Region: PGAP1; pfam07819
761193013299	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193013300	Serine hydrolase; Region: Ser_hydrolase; cl17834
761193013301	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
761193013302	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
761193013303	MarR family; Region: MarR_2; pfam12802
761193013304	YceI-like domain; Region: YceI; pfam04264
761193013305	MORN repeat; Region: MORN; cl14787
761193013306	MORN repeat; Region: MORN; pfam02493
761193013307	Protein of unknown function DUF72; Region: DUF72; pfam01904
761193013308	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467
761193013309	iron-sulfur cluster [ion binding]; other site
761193013310	[2Fe-2S] cluster binding site [ion binding]; other site
761193013311	YceI-like domain; Region: YceI; pfam04264
761193013312	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193013313	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193013314	Enoyl-(Acyl carrier protein) reductase; Region: adh_short_C2; pfam13561
761193013315	NAD(P) binding site [chemical binding]; other site
761193013316	active site
761193013317	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
761193013318	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193013319	Walker A/P-loop; other site
761193013320	ATP binding site [chemical binding]; other site
761193013321	Q-loop/lid; other site
761193013322	ABC transporter signature motif; other site
761193013323	Walker B; other site
761193013324	D-loop; other site
761193013325	H-loop/switch region; other site
761193013326	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
761193013327	tandem repeat interface [polypeptide binding]; other site
761193013328	oligomer interface [polypeptide binding]; other site
761193013329	active site residues [active]
761193013330	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
761193013331	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
761193013332	tandem repeat interface [polypeptide binding]; other site
761193013333	oligomer interface [polypeptide binding]; other site
761193013334	active site residues [active]
761193013335	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
761193013336	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
761193013337	Transposase; Region: DDE_Tnp_ISL3; pfam01610
761193013338	Histidine kinase; Region: HisKA_3; pfam07730
761193013339	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193013340	ATP binding site [chemical binding]; other site
761193013341	Mg2+ binding site [ion binding]; other site
761193013342	G-X-G motif; other site
761193013343	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
761193013344	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193013345	active site
761193013346	phosphorylation site [posttranslational modification]
761193013347	intermolecular recognition site; other site
761193013348	dimerization interface [polypeptide binding]; other site
761193013349	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
761193013350	DNA binding residues [nucleotide binding]
761193013351	dimerization interface [polypeptide binding]; other site
761193013352	Catalytic domain of Protein Kinases; Region: PKc; cd00180
761193013353	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
761193013354	active site
761193013355	ATP binding site [chemical binding]; other site
761193013356	substrate binding site [chemical binding]; other site
761193013357	activation loop (A-loop); other site
761193013358	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193013359	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
761193013360	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
761193013361	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193013362	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193013363	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
761193013364	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193013365	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193013366	ligand binding site [chemical binding]; other site
761193013367	Caspase domain; Region: Peptidase_C14; pfam00656
761193013368	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
761193013369	Protein phosphatase 2C; Region: PP2C; pfam00481
761193013370	active site
761193013371	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
761193013372	phosphopeptide binding site; other site
761193013373	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
761193013374	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
761193013375	phosphopeptide binding site; other site
761193013376	FOG: PKD repeat [General function prediction only]; Region: COG3291
761193013377	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
761193013378	VWFA-related Acidobacterial domain; Region: acidobact_VWFA; TIGR03436
761193013379	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
761193013380	metal ion-dependent adhesion site (MIDAS); other site
761193013381	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
761193013382	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193013383	Walker A motif; other site
761193013384	ATP binding site [chemical binding]; other site
761193013385	Walker B motif; other site
761193013386	arginine finger; other site
761193013387	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193013388	ATP binding site [chemical binding]; other site
761193013389	Walker B motif; other site
761193013390	arginine finger; other site
761193013391	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
761193013392	Protein of unknown function (DUF877); Region: DUF877; pfam05943
761193013393	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
761193013394	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
761193013395	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
761193013396	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
761193013397	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522; cl01406
761193013398	Uncharacterized conserved protein [Function unknown]; Region: COG4104
761193013399	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193013400	active site residue [active]
761193013401	KEGG: dfe:Dfer_3825 hypothetical protein; SPTR:  uncharacterized protein
761193013402	M28 Zn-Peptidases; Region: M28_like_6; cd08656
761193013403	Peptidase family M28; Region: Peptidase_M28; pfam04389
761193013404	metal binding site [ion binding]; metal-binding site
761193013405	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
761193013406	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
761193013407	active site
761193013408	catalytic triad [active]
761193013409	oxyanion hole [active]
761193013410	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
761193013411	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193013412	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193013413	Cadherin repeat-like domain; Region: CA_like; cl15786
761193013414	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193013415	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193013416	Cadherin repeat-like domain; Region: CA_like; cl15786
761193013417	Ca2+ binding site [ion binding]; other site
761193013418	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
761193013419	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193013420	Cadherin repeat-like domain; Region: CA_like; cl15786
761193013421	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
761193013422	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193013423	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
761193013424	conserved cys residue [active]
761193013425	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
761193013426	EamA-like transporter family; Region: EamA; pfam00892
761193013427	EamA-like transporter family; Region: EamA; pfam00892
761193013428	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
761193013429	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
761193013430	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
761193013431	active site
761193013432	universal stress protein UspE; Provisional; Region: PRK11175
761193013433	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
761193013434	Ligand Binding Site [chemical binding]; other site
761193013435	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
761193013436	Ligand Binding Site [chemical binding]; other site
761193013437	Response regulator receiver domain; Region: Response_reg; pfam00072
761193013438	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193013439	active site
761193013440	phosphorylation site [posttranslational modification]
761193013441	intermolecular recognition site; other site
761193013442	dimerization interface [polypeptide binding]; other site
761193013443	PglZ domain; Region: PglZ; pfam08665
761193013444	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193013445	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193013446	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
761193013447	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
761193013448	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
761193013449	metal-binding site [ion binding]
761193013450	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
761193013451	Soluble P-type ATPase [General function prediction only]; Region: COG4087
761193013452	Cytochrome oxidase maturation protein cbb3-type; Region: CcoS; pfam03597
761193013453	putative bifunctional cbb3-type cytochrome c oxidase subunit I/II; Provisional; Region: PRK14485
761193013454	Cytochrome cbb3 oxidase subunit I.  Cytochrome cbb3 oxidase, the terminal oxidase in the respiratory chains of proteobacteria, is a multi-chain transmembrane protein located in the cell membrane. Like other cytochrome oxidases, it catalyzes the reduction...; Region: cbb3_Oxidase_I; cd01661
761193013455	Low-spin heme binding site [chemical binding]; other site
761193013456	Putative water exit pathway; other site
761193013457	Binuclear center (active site) [active]
761193013458	Putative proton exit pathway; other site
761193013459	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; pfam02433
761193013460	Uncharacterized protein family (UPF0233); Region: UPF0233; cl11506
761193013461	Cytochrome c; Region: Cytochrom_C; cl11414
761193013462	Cytochrome c; Region: Cytochrom_C; pfam00034
761193013463	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
761193013464	4Fe-4S binding domain; Region: Fer4_5; pfam12801
761193013465	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
761193013466	FixH; Region: FixH; pfam05751
761193013467	Family description; Region: DsbD_2; pfam13386
761193013468	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
761193013469	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193013470	FeS/SAM binding site; other site
761193013471	HemN C-terminal domain; Region: HemN_C; pfam06969
761193013472	PAS domain S-box; Region: sensory_box; TIGR00229
761193013473	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193013474	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193013475	dimer interface [polypeptide binding]; other site
761193013476	phosphorylation site [posttranslational modification]
761193013477	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193013478	ATP binding site [chemical binding]; other site
761193013479	Mg2+ binding site [ion binding]; other site
761193013480	G-X-G motif; other site
761193013481	Response regulator receiver domain; Region: Response_reg; pfam00072
761193013482	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193013483	active site
761193013484	phosphorylation site [posttranslational modification]
761193013485	intermolecular recognition site; other site
761193013486	dimerization interface [polypeptide binding]; other site
761193013487	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193013488	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193013489	ligand binding site [chemical binding]; other site
761193013490	flexible hinge region; other site
761193013491	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
761193013492	putative switch regulator; other site
761193013493	non-specific DNA interactions [nucleotide binding]; other site
761193013494	DNA binding site [nucleotide binding]
761193013495	sequence specific DNA binding site [nucleotide binding]; other site
761193013496	putative cAMP binding site [chemical binding]; other site
761193013497	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
761193013498	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193013499	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193013500	ABC transporter; Region: ABC_tran_2; pfam12848
761193013501	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
761193013502	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
761193013503	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
761193013504	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
761193013505	active site
761193013506	HIGH motif; other site
761193013507	nucleotide binding site [chemical binding]; other site
761193013508	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
761193013509	KMSKS motif; other site
761193013510	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
761193013511	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
761193013512	active site
761193013513	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
761193013514	GTP cyclohydrolase I; Provisional; Region: PLN03044
761193013515	active site
761193013516	Tetratricopeptide repeat; Region: TPR_12; pfam13424
761193013517	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cl01898
761193013518	putative active site [active]
761193013519	transcription elongation factor GreA; Region: greA; TIGR01462
761193013520	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
761193013521	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
761193013522	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
761193013523	active site
761193013524	catalytic tetrad [active]
761193013525	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
761193013526	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193013527	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
761193013528	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
761193013529	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
761193013530	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
761193013531	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
761193013532	Domain of unknown function DUF21; Region: DUF21; pfam01595
761193013533	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
761193013534	Transporter associated domain; Region: CorC_HlyC; smart01091
761193013535	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
761193013536	active site
761193013537	Ap6A binding site [chemical binding]; other site
761193013538	nudix motif; other site
761193013539	metal binding site [ion binding]; metal-binding site
761193013540	HsdM N-terminal domain; Region: HsdM_N; pfam12161
761193013541	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
761193013542	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
761193013543	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
761193013544	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
761193013545	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193013546	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
761193013547	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193013548	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
761193013549	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
761193013550	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
761193013551	ATP binding site [chemical binding]; other site
761193013552	putative Mg++ binding site [ion binding]; other site
761193013553	Protein of unknown function DUF45; Region: DUF45; pfam01863
761193013554	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
761193013555	active site
761193013556	Ricin-type beta-trefoil lectin domain-like; Region: RicinB_lectin_2; pfam14200
761193013557	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
761193013558	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
761193013559	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
761193013560	Walker A/P-loop; other site
761193013561	ATP binding site [chemical binding]; other site
761193013562	Q-loop/lid; other site
761193013563	ABC transporter signature motif; other site
761193013564	Walker B; other site
761193013565	D-loop; other site
761193013566	H-loop/switch region; other site
761193013567	ABC exporter membrane fusion protein, DevB family; Region: heterocyst_DevB; TIGR02971
761193013568	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193013569	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193013570	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
761193013571	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193013572	FtsX-like permease family; Region: FtsX; pfam02687
761193013573	Outer membrane efflux protein; Region: OEP; pfam02321
761193013574	Outer membrane efflux protein; Region: OEP; pfam02321
761193013575	Prodigal; manually curated
761193013576	InterPro IPR003346; KEGG: sli:Slin_6004 transposase IS116/IS110/IS902 family protein; PFAM: Transposase, IS116/IS110/IS902; SPTR: Transposase IS116/IS110/IS902 family protein
761193013577	Transposase; Region: DEDD_Tnp_IS110; pfam01548
761193013578	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
761193013579	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
761193013580	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193013581	Walker A motif; other site
761193013582	ATP binding site [chemical binding]; other site
761193013583	Walker B motif; other site
761193013584	arginine finger; other site
761193013585	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
761193013586	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
761193013587	Transposase; Region: DDE_Tnp_ISL3; pfam01610
761193013588	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
761193013589	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193013590	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
761193013591	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193013592	catalytic residue [active]
761193013593	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
761193013594	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193013595	Coenzyme A binding pocket [chemical binding]; other site
761193013596	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
761193013597	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
761193013598	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
761193013599	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
761193013600	substrate binding pocket [chemical binding]; other site
761193013601	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
761193013602	B12 binding site [chemical binding]; other site
761193013603	cobalt ligand [ion binding]; other site
761193013604	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
761193013605	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193013606	putative outer membrane lipoprotein; Provisional; Region: PRK10510
761193013607	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193013608	ligand binding site [chemical binding]; other site
761193013609	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
761193013610	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
761193013611	dimerization interface [polypeptide binding]; other site
761193013612	putative DNA binding site [nucleotide binding]; other site
761193013613	putative Zn2+ binding site [ion binding]; other site
761193013614	AsnC family; Region: AsnC_trans_reg; pfam01037
761193013615	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
761193013616	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
761193013617	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
761193013618	putative active site [active]
761193013619	putative CoA binding site [chemical binding]; other site
761193013620	nudix motif; other site
761193013621	metal binding site [ion binding]; metal-binding site
761193013622	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
761193013623	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
761193013624	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
761193013625	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
761193013626	putative active site [active]
761193013627	replicative DNA helicase; Region: DnaB; TIGR00665
761193013628	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
761193013629	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
761193013630	Walker A motif; other site
761193013631	ATP binding site [chemical binding]; other site
761193013632	Walker B motif; other site
761193013633	DNA binding loops [nucleotide binding]
761193013634	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
761193013635	Predicted aminopeptidase (DUF2265); Region: DUF2265; cl17720
761193013636	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
761193013637	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
761193013638	Protein of unknown function (DUF721); Region: DUF721; pfam05258
761193013639	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
761193013640	Clp amino terminal domain; Region: Clp_N; pfam02861
761193013641	Clp amino terminal domain; Region: Clp_N; pfam02861
761193013642	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193013643	Walker A motif; other site
761193013644	ATP binding site [chemical binding]; other site
761193013645	Walker B motif; other site
761193013646	arginine finger; other site
761193013647	UvrB/uvrC motif; Region: UVR; pfam02151
761193013648	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193013649	Walker A motif; other site
761193013650	ATP binding site [chemical binding]; other site
761193013651	Walker B motif; other site
761193013652	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
761193013653	WbqC-like protein family; Region: WbqC; pfam08889
761193013654	Creatinine amidohydrolase; Region: Creatininase; pfam02633
761193013655	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
761193013656	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
761193013657	putative acyl-acceptor binding pocket; other site
761193013658	InterPro IPR000182; KEGG: ran:Riean_1382 spermine/spermidine N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: N-acetyltransferase
761193013659	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
761193013660	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193013661	Coenzyme A binding pocket [chemical binding]; other site
761193013662	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
761193013663	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193013664	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193013665	non-specific DNA binding site [nucleotide binding]; other site
761193013666	salt bridge; other site
761193013667	sequence-specific DNA binding site [nucleotide binding]; other site
761193013668	Predicted transcriptional regulator [Transcription]; Region: COG2932
761193013669	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
761193013670	Catalytic site [active]
761193013671	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
761193013672	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
761193013673	Catalytic site [active]
761193013674	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
761193013675	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
761193013676	active site
761193013677	DNA binding site [nucleotide binding]
761193013678	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
761193013679	SPTR: Transposase IS4 family protein
761193013680	COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sli:Slin_1040 response regulator receiver sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver sensor signal transduction histidine kinase
761193013681	Response regulator receiver domain; Region: Response_reg; pfam00072
761193013682	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193013683	active site
761193013684	phosphorylation site [posttranslational modification]
761193013685	intermolecular recognition site; other site
761193013686	dimerization interface [polypeptide binding]; other site
761193013687	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193013688	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193013689	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193013690	putative active site [active]
761193013691	heme pocket [chemical binding]; other site
761193013692	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193013693	putative active site [active]
761193013694	heme pocket [chemical binding]; other site
761193013695	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193013696	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193013697	dimer interface [polypeptide binding]; other site
761193013698	phosphorylation site [posttranslational modification]
761193013699	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193013700	ATP binding site [chemical binding]; other site
761193013701	Mg2+ binding site [ion binding]; other site
761193013702	G-X-G motif; other site
761193013703	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193013704	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193013705	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
761193013706	Transposase; Region: DDE_Tnp_ISL3; pfam01610
761193013707	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
761193013708	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
761193013709	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
761193013710	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
761193013711	putative ligand binding site [chemical binding]; other site
761193013712	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
761193013713	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193013714	motif II; other site
761193013715	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193013716	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193013717	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193013718	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193013719	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
761193013720	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
761193013721	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
761193013722	Amidohydrolase; Region: Amidohydro_2; pfam04909
761193013723	Kelch motif; Region: Kelch_2; pfam07646
761193013724	Galactose oxidase, central domain; Region: Kelch_3; cl02701
761193013725	Kelch motif; Region: Kelch_1; pfam01344
761193013726	Kelch motif; Region: Kelch_1; pfam01344
761193013727	Galactose oxidase, central domain; Region: Kelch_4; pfam13418
761193013728	Kelch motif; Region: Kelch_6; pfam13964
761193013729	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193013730	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193013731	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
761193013732	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
761193013733	hydrophobic ligand binding site; other site
761193013734	Family description; Region: VCBS; pfam13517
761193013735	Family description; Region: VCBS; pfam13517
761193013736	Family description; Region: VCBS; pfam13517
761193013737	Family description; Region: VCBS; pfam13517
761193013738	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
761193013739	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193013740	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
761193013741	active site
761193013742	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193013743	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
761193013744	active site
761193013745	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
761193013746	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
761193013747	inhibitor-cofactor binding pocket; inhibition site
761193013748	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193013749	catalytic residue [active]
761193013750	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
761193013751	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
761193013752	active site
761193013753	catalytic tetrad [active]
761193013754	Putative Zn-dependent protease [General function prediction only]; Region: COG4784
761193013755	Peptidase family M48; Region: Peptidase_M48; pfam01435
761193013756	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
761193013757	DNA protecting protein DprA; Region: dprA; TIGR00732
761193013758	Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069
761193013759	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
761193013760	active site
761193013761	FMN binding site [chemical binding]; other site
761193013762	substrate binding site [chemical binding]; other site
761193013763	3Fe-4S cluster binding site [ion binding]; other site
761193013764	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
761193013765	COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: dfe:Dfer_0035 endonuclease/exonuclease/phosphatase; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase
761193013766	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2; Region: EEP-2; cd09084
761193013767	putative catalytic site [active]
761193013768	putative metal binding site [ion binding]; other site
761193013769	putative phosphate binding site [ion binding]; other site
761193013770	Family description; Region: VCBS; pfam13517
761193013771	Family description; Region: VCBS; pfam13517
761193013772	Family description; Region: VCBS; pfam13517
761193013773	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
761193013774	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
761193013775	active site
761193013776	substrate-binding site [chemical binding]; other site
761193013777	metal-binding site [ion binding]
761193013778	ATP binding site [chemical binding]; other site
761193013779	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193013780	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193013781	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
761193013782	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
761193013783	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
761193013784	competence damage-inducible protein A; Provisional; Region: PRK00549
761193013785	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
761193013786	putative MPT binding site; other site
761193013787	Competence-damaged protein; Region: CinA; pfam02464
761193013788	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
761193013789	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
761193013790	E3 interaction surface; other site
761193013791	lipoyl attachment site [posttranslational modification]; other site
761193013792	e3 binding domain; Region: E3_binding; pfam02817
761193013793	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
761193013794	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193013795	TAP-like protein; Region: Abhydrolase_4; pfam08386
761193013796	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
761193013797	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193013798	Coenzyme A binding pocket [chemical binding]; other site
761193013799	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193013800	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193013801	ligand binding site [chemical binding]; other site
761193013802	flexible hinge region; other site
761193013803	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
761193013804	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
761193013805	NAD(P) binding site [chemical binding]; other site
761193013806	active site
761193013807	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
761193013808	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
761193013809	ligand binding site [chemical binding]; other site
761193013810	flexible hinge region; other site
761193013811	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
761193013812	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
761193013813	metal ion-dependent adhesion site (MIDAS); other site
761193013814	Methyltransferase domain; Region: Methyltransf_23; pfam13489
761193013815	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193013816	S-adenosylmethionine binding site [chemical binding]; other site
761193013817	bacillithiol system oxidoreductase, YphP/YqiW family; Region: YphP_YqiW; TIGR04191
761193013818	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
761193013819	Fe-S metabolism associated domain; Region: SufE; cl00951
761193013820	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
761193013821	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
761193013822	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
761193013823	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193013824	catalytic residue [active]
761193013825	YtxH-like protein; Region: YtxH; pfam12732
761193013826	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
761193013827	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
761193013828	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
761193013829	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
761193013830	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
761193013831	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
761193013832	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
761193013833	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
761193013834	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
761193013835	homodimer interface [polypeptide binding]; other site
761193013836	substrate-cofactor binding pocket; other site
761193013837	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193013838	catalytic residue [active]
761193013839	Protein of unknown function (DUF1684); Region: DUF1684; pfam07920
761193013840	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
761193013841	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
761193013842	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
761193013843	COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: sli:Slin_1920 ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; SPTR: ComEC/Rec2-related protein; TIGRFAM: ComEC/Rec2-related protein
761193013844	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
761193013845	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
761193013846	Competence protein; Region: Competence; pfam03772
761193013847	Zinc-dependent metalloprotease, pappalysin_like subfamily. The pregnancy-associated plasma protein A (PAPP-A or pappalysin-1) cleaves insulin-like growth factor-binding proteins 4 and 5, thereby promoting cell growth by releasing bound growth factor; Region: ZnMc_pappalysin_like; cd04275
761193013848	active site
761193013849	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193013850	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
761193013851	PhoH-like protein; Region: PhoH; pfam02562
761193013852	choice-of-anchor A domain; Region: choice_anch_A; TIGR04215
761193013853	PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398
761193013854	active site
761193013855	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
761193013856	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13540
761193013857	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193013858	Walker A/P-loop; other site
761193013859	ATP binding site [chemical binding]; other site
761193013860	Q-loop/lid; other site
761193013861	ABC transporter signature motif; other site
761193013862	Walker B; other site
761193013863	D-loop; other site
761193013864	H-loop/switch region; other site
761193013865	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193013866	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193013867	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193013868	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14970
761193013869	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193013870	Walker A motif; other site
761193013871	ATP binding site [chemical binding]; other site
761193013872	Walker B motif; other site
761193013873	arginine finger; other site
761193013874	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258
761193013875	MOSC domain; Region: MOSC; pfam03473
761193013876	Protein of unknown function, DUF479; Region: DUF479; cl01203
761193013877	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
761193013878	catalytic motif [active]
761193013879	Zn binding site [ion binding]; other site
761193013880	Demethylmenaquinone methyltransferase; Region: Methyltransf_6; cl00480
761193013881	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
761193013882	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
761193013883	active site pocket [active]
761193013884	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
761193013885	Uncharacterized conserved protein [Function unknown]; Region: COG3743
761193013886	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193013887	ligand binding site [chemical binding]; other site
761193013888	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
761193013889	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
761193013890	ligand binding site [chemical binding]; other site
761193013891	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
761193013892	FAD binding site [chemical binding]; other site
761193013893	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
761193013894	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
761193013895	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
761193013896	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
761193013897	Methyltransferase domain; Region: Methyltransf_11; pfam08241
761193013898	shikimate kinase; Reviewed; Region: aroK; PRK00131
761193013899	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
761193013900	ADP binding site [chemical binding]; other site
761193013901	magnesium binding site [ion binding]; other site
761193013902	putative shikimate binding site; other site
761193013903	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
761193013904	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
761193013905	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
761193013906	dihydropteroate synthase; Region: DHPS; TIGR01496
761193013907	substrate binding pocket [chemical binding]; other site
761193013908	dimer interface [polypeptide binding]; other site
761193013909	inhibitor binding site; inhibition site
761193013910	Predicted membrane protein [Function unknown]; Region: COG2259
761193013911	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
761193013912	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
761193013913	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
761193013914	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
761193013915	RIP metalloprotease RseP; Region: TIGR00054
761193013916	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
761193013917	active site
761193013918	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
761193013919	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
761193013920	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
761193013921	putative substrate binding region [chemical binding]; other site
761193013922	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
761193013923	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
761193013924	23S rRNA binding site [nucleotide binding]; other site
761193013925	L21 binding site [polypeptide binding]; other site
761193013926	L13 binding site [polypeptide binding]; other site
761193013927	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193013928	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193013929	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193013930	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193013931	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193013932	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
761193013933	metal-binding site [ion binding]
761193013934	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193013935	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
761193013936	DNA-binding site [nucleotide binding]; DNA binding site
761193013937	RNA-binding motif; other site
761193013938	Response regulator receiver domain; Region: Response_reg; pfam00072
761193013939	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193013940	active site
761193013941	phosphorylation site [posttranslational modification]
761193013942	intermolecular recognition site; other site
761193013943	dimerization interface [polypeptide binding]; other site
761193013944	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193013945	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193013946	ATP binding site [chemical binding]; other site
761193013947	Mg2+ binding site [ion binding]; other site
761193013948	G-X-G motif; other site
761193013949	Response regulator receiver domain; Region: Response_reg; pfam00072
761193013950	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193013951	active site
761193013952	phosphorylation site [posttranslational modification]
761193013953	intermolecular recognition site; other site
761193013954	dimerization interface [polypeptide binding]; other site
761193013955	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193013956	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193013957	YhhN-like protein; Region: YhhN; pfam07947
761193013958	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
761193013959	dimer interface [polypeptide binding]; other site
761193013960	substrate binding site [chemical binding]; other site
761193013961	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
761193013962	metal binding site [ion binding]; metal-binding site
761193013963	Family of unknown function (DUF706); Region: DUF706; pfam05153
761193013964	Transcriptional regulators [Transcription]; Region: PurR; COG1609
761193013965	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
761193013966	DNA binding site [nucleotide binding]
761193013967	domain linker motif; other site
761193013968	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
761193013969	dimerization interface [polypeptide binding]; other site
761193013970	ligand binding site [chemical binding]; other site
761193013971	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
761193013972	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
761193013973	AIR carboxylase; Region: AIRC; pfam00731
761193013974	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193013975	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
761193013976	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
761193013977	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
761193013978	putative active site [active]
761193013979	putative metal binding site [ion binding]; other site
761193013980	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
761193013981	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
761193013982	putative trimer interface [polypeptide binding]; other site
761193013983	putative CoA binding site [chemical binding]; other site
761193013984	recombination protein F; Reviewed; Region: recF; PRK00064
761193013985	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193013986	Walker A/P-loop; other site
761193013987	ATP binding site [chemical binding]; other site
761193013988	Q-loop/lid; other site
761193013989	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193013990	ABC transporter signature motif; other site
761193013991	Walker B; other site
761193013992	D-loop; other site
761193013993	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
761193013994	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
761193013995	tetramer interface [polypeptide binding]; other site
761193013996	TPP-binding site [chemical binding]; other site
761193013997	heterodimer interface [polypeptide binding]; other site
761193013998	phosphorylation loop region [posttranslational modification]
761193013999	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
761193014000	Permease; Region: Permease; pfam02405
761193014001	MarR family; Region: MarR_2; cl17246
761193014002	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
761193014003	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
761193014004	nucleotide binding site [chemical binding]; other site
761193014005	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
761193014006	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193014007	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193014008	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193014009	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193014010	starch binding outer membrane protein SusD; Region: SusD; cl17845
761193014011	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
761193014012	RES domain; Region: RES; pfam08808
761193014013	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
761193014014	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193014015	catalytic residues [active]
761193014016	HEPN domain; Region: HEPN; cl00824
761193014017	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
761193014018	active site
761193014019	NTP binding site [chemical binding]; other site
761193014020	metal binding triad [ion binding]; metal-binding site
761193014021	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
761193014022	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
761193014023	FtsX-like permease family; Region: FtsX; pfam02687
761193014024	FtsX-like permease family; Region: FtsX; pfam02687
761193014025	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
761193014026	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
761193014027	Walker A/P-loop; other site
761193014028	ATP binding site [chemical binding]; other site
761193014029	Q-loop/lid; other site
761193014030	ABC transporter signature motif; other site
761193014031	Walker B; other site
761193014032	D-loop; other site
761193014033	H-loop/switch region; other site
761193014034	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
761193014035	active site
761193014036	catalytic triad [active]
761193014037	oxyanion hole [active]
761193014038	switch loop; other site
761193014039	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
761193014040	Asp-box motif; other site
761193014041	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
761193014042	active site
761193014043	catalytic residues [active]
761193014044	BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure; Region: KU; cd00109
761193014045	trypsin interaction site; other site
761193014046	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
761193014047	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
761193014048	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721
761193014049	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
761193014050	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193014051	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
761193014052	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
761193014053	TIGR02646 family protein; Region: TIGR02646
761193014054	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193014055	AAA domain; Region: AAA_21; pfam13304
761193014056	Walker A/P-loop; other site
761193014057	ATP binding site [chemical binding]; other site
761193014058	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193014059	Walker A/P-loop; other site
761193014060	ATP binding site [chemical binding]; other site
761193014061	Q-loop/lid; other site
761193014062	ABC transporter signature motif; other site
761193014063	Walker B; other site
761193014064	D-loop; other site
761193014065	H-loop/switch region; other site
761193014066	PGAP1-like protein; Region: PGAP1; pfam07819
761193014067	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193014068	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
761193014069	Protein of unknown function DUF58; Region: DUF58; pfam01882
761193014070	tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Region: TIGR00057
761193014071	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
761193014072	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
761193014073	active site
761193014074	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
761193014075	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193014076	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193014077	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193014078	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
761193014079	active site
761193014080	YceG-like family; Region: YceG; pfam02618
761193014081	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
761193014082	dimerization interface [polypeptide binding]; other site
761193014083	DinB superfamily; Region: DinB_2; pfam12867
761193014084	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
761193014085	Phosphoesterase family; Region: Phosphoesterase; pfam04185
761193014086	Phosphoesterase family; Region: Phosphoesterase; pfam04185
761193014087	Domain of unknown function (DUF756); Region: DUF756; pfam05506
761193014088	Domain of unknown function (DUF756); Region: DUF756; pfam05506
761193014089	Cytochrome C subunit of the bacterial photosynthetic reaction center; Region: CytoC_RC; cl12263
761193014090	Heme binding sites [chemical binding]; other site
761193014091	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
761193014092	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
761193014093	COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: lby:Lbys_1032 oxidoreductase domain protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein
761193014094	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
761193014095	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
761193014096	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
761193014097	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193014098	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193014099	putative substrate translocation pore; other site
761193014100	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193014101	binding surface
761193014102	TPR motif; other site
761193014103	TPR repeat; Region: TPR_11; pfam13414
761193014104	TPR repeat; Region: TPR_11; pfam13414
761193014105	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
761193014106	TPR motif; other site
761193014107	TPR repeat; Region: TPR_11; pfam13414
761193014108	binding surface
761193014109	legume lectins; Region: lectin_L-type; cl14058
761193014110	carbohydrate binding site [chemical binding]; other site
761193014111	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
761193014112	amphipathic channel; other site
761193014113	Asn-Pro-Ala signature motifs; other site
761193014114	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
761193014115	Trp docking motif [polypeptide binding]; other site
761193014116	putative active site [active]
761193014117	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193014118	Cytochrome c; Region: Cytochrom_C; pfam00034
761193014119	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
761193014120	adenylosuccinate lyase; Provisional; Region: PRK09285
761193014121	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
761193014122	tetramer interface [polypeptide binding]; other site
761193014123	active site
761193014124	Predicted amidohydrolase [General function prediction only]; Region: COG0388
761193014125	Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564
761193014126	putative active site [active]
761193014127	catalytic triad [active]
761193014128	putative dimer interface [polypeptide binding]; other site
761193014129	4-aminobutyrate aminotransferase; Provisional; Region: PRK06082
761193014130	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
761193014131	inhibitor-cofactor binding pocket; inhibition site
761193014132	pyridoxal 5'-phosphate binding site [chemical binding]; other site
761193014133	catalytic residue [active]
761193014134	Domain of unknown function DUF20; Region: UPF0118; pfam01594
761193014135	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
761193014136	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
761193014137	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
761193014138	acyl-activating enzyme (AAE) consensus motif; other site
761193014139	putative AMP binding site [chemical binding]; other site
761193014140	putative active site [active]
761193014141	putative CoA binding site [chemical binding]; other site
761193014142	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
761193014143	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
761193014144	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
761193014145	Histidine kinase; Region: HisKA_3; pfam07730
761193014146	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193014147	Mg2+ binding site [ion binding]; other site
761193014148	G-X-G motif; other site
761193014149	Glycosyl hydrolase family 43, includes mostly 1,4-beta-xylanases; Region: GH43_bXyl; cd09004
761193014150	putative substrate binding site [chemical binding]; other site
761193014151	active site
761193014152	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
761193014153	dimer interface [polypeptide binding]; other site
761193014154	catalytic triad [active]
761193014155	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
761193014156	signal recognition particle protein; Provisional; Region: PRK10867
761193014157	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
761193014158	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
761193014159	P loop; other site
761193014160	GTP binding site [chemical binding]; other site
761193014161	Signal peptide binding domain; Region: SRP_SPB; pfam02978
761193014162	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193014163	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193014164	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
761193014165	NADH dehydrogenase subunit B; Provisional; Region: PRK14820
761193014166	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
761193014167	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
761193014168	NADH dehydrogenase subunit D; Validated; Region: PRK06075
761193014169	NADH dehydrogenase subunit E; Validated; Region: PRK07539
761193014170	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
761193014171	putative dimer interface [polypeptide binding]; other site
761193014172	[2Fe-2S] cluster binding site [ion binding]; other site
761193014173	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
761193014174	SLBB domain; Region: SLBB; pfam10531
761193014175	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
761193014176	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193014177	catalytic loop [active]
761193014178	iron binding site [ion binding]; other site
761193014179	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
761193014180	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
761193014181	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
761193014182	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
761193014183	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
761193014184	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
761193014185	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
761193014186	NADH dehydrogenase subunit 6; Provisional; Region: ND6; MTH00213
761193014187	DNA alkylation repair enzyme [DNA replication, recombination, and repair]; Region: COG4335
761193014188	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
761193014189	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
761193014190	substrate binding site [chemical binding]; other site
761193014191	oxyanion hole (OAH) forming residues; other site
761193014192	trimer interface [polypeptide binding]; other site
761193014193	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
761193014194	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
761193014195	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
761193014196	acetyl-CoA acetyltransferase; Validated; Region: PRK08242
761193014197	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
761193014198	dimer interface [polypeptide binding]; other site
761193014199	active site
761193014200	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193014201	D-galactonate transporter; Region: 2A0114; TIGR00893
761193014202	putative substrate translocation pore; other site
761193014203	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193014204	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
761193014205	catalytic core [active]
761193014206	similar to UDP-N-acetylglucosamine1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR000748:IPR006145; KEGG: chu:CHU_1012 RNA pseudouridylate synthase small subunit; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA and RluB/E/F
761193014207	similar to pseudouridine synthase Rsu; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase; COGs: COG3652 outer membrane protein; KEGG: sus:Acid_6666 outer membrane protein; SPTR: Outer membrane protein
761193014208	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
761193014209	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
761193014210	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193014211	PAS domain S-box; Region: sensory_box; TIGR00229
761193014212	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193014213	putative active site [active]
761193014214	heme pocket [chemical binding]; other site
761193014215	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193014216	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193014217	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193014218	putative active site [active]
761193014219	heme pocket [chemical binding]; other site
761193014220	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
761193014221	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193014222	putative active site [active]
761193014223	heme pocket [chemical binding]; other site
761193014224	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193014225	dimer interface [polypeptide binding]; other site
761193014226	phosphorylation site [posttranslational modification]
761193014227	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193014228	ATP binding site [chemical binding]; other site
761193014229	Mg2+ binding site [ion binding]; other site
761193014230	G-X-G motif; other site
761193014231	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193014232	PAS domain; Region: PAS_9; pfam13426
761193014233	putative active site [active]
761193014234	heme pocket [chemical binding]; other site
761193014235	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193014236	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193014237	dimer interface [polypeptide binding]; other site
761193014238	phosphorylation site [posttranslational modification]
761193014239	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193014240	ATP binding site [chemical binding]; other site
761193014241	Mg2+ binding site [ion binding]; other site
761193014242	G-X-G motif; other site
761193014243	GAF domain; Region: GAF_3; pfam13492
761193014244	GAF domain; Region: GAF_2; pfam13185
761193014245	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
761193014246	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193014247	dimer interface [polypeptide binding]; other site
761193014248	phosphorylation site [posttranslational modification]
761193014249	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193014250	ATP binding site [chemical binding]; other site
761193014251	Mg2+ binding site [ion binding]; other site
761193014252	G-X-G motif; other site
761193014253	Response regulator receiver domain; Region: Response_reg; pfam00072
761193014254	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193014255	active site
761193014256	phosphorylation site [posttranslational modification]
761193014257	intermolecular recognition site; other site
761193014258	dimerization interface [polypeptide binding]; other site
761193014259	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193014260	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
761193014261	putative active site [active]
761193014262	heme pocket [chemical binding]; other site
761193014263	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
761193014264	putative active site [active]
761193014265	heme pocket [chemical binding]; other site
761193014266	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
761193014267	dimer interface [polypeptide binding]; other site
761193014268	phosphorylation site [posttranslational modification]
761193014269	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193014270	ATP binding site [chemical binding]; other site
761193014271	Mg2+ binding site [ion binding]; other site
761193014272	G-X-G motif; other site
761193014273	putative hydrolase; Provisional; Region: PRK02113
761193014274	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
761193014275	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
761193014276	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193014277	active site
761193014278	phosphorylation site [posttranslational modification]
761193014279	intermolecular recognition site; other site
761193014280	dimerization interface [polypeptide binding]; other site
761193014281	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
761193014282	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
761193014283	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193014284	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193014285	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193014286	Predicted methyltransferases [General function prediction only]; Region: COG0313
761193014287	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
761193014288	putative SAM binding site [chemical binding]; other site
761193014289	putative homodimer interface [polypeptide binding]; other site
761193014290	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
761193014291	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
761193014292	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
761193014293	active site
761193014294	dimerization interface [polypeptide binding]; other site
761193014295	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
761193014296	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
761193014297	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
761193014298	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
761193014299	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
761193014300	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193014301	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
761193014302	Fn3 associated; Region: Fn3_assoc; pfam13287
761193014303	Protein of unknown function (DUF1501); Region: DUF1501; pfam07394
761193014304	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193014305	Protein of unknown function (DUF1549); Region: PSCyt2; pfam07583
761193014306	Protein of unknown function (DUF1553); Region: PSD1; pfam07587
761193014307	Protein of unknown function (DUF1501); Region: DUF1501; pfam07394
761193014308	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
761193014309	Protein of unknown function (DUF1549); Region: PSCyt2; pfam07583
761193014310	Protein of unknown function (DUF1553); Region: PSD1; pfam07587
761193014311	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193014312	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
761193014313	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193014314	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193014315	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193014316	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193014317	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cd00229
761193014318	active site
761193014319	catalytic triad [active]
761193014320	oxyanion hole [active]
761193014321	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
761193014322	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
761193014323	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
761193014324	DNA binding residues [nucleotide binding]
761193014325	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
761193014326	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
761193014327	AMP binding site [chemical binding]; other site
761193014328	metal binding site [ion binding]; metal-binding site
761193014329	active site
761193014330	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
761193014331	Phosphotransferase enzyme family; Region: APH; pfam01636
761193014332	active site
761193014333	substrate binding site [chemical binding]; other site
761193014334	ATP binding site [chemical binding]; other site
761193014335	Ecdysteroid kinase; Region: EcKinase; cl17738
761193014336	substrate binding site [chemical binding]; other site
761193014337	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
761193014338	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
761193014339	catalytic motif [active]
761193014340	Catalytic residue [active]
761193014341	Aspartyl protease; Region: Asp_protease_2; pfam13650
761193014342	inhibitor binding site; inhibition site
761193014343	catalytic motif [active]
761193014344	Catalytic residue [active]
761193014345	Active site flap [active]
761193014346	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cd00136
761193014347	protein binding site [polypeptide binding]; other site
761193014348	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
761193014349	triosephosphate isomerase; Provisional; Region: PRK14565
761193014350	substrate binding site [chemical binding]; other site
761193014351	dimer interface [polypeptide binding]; other site
761193014352	catalytic triad [active]
761193014353	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
761193014354	C-N hydrolase family amidase; Provisional; Region: PRK10438
761193014355	putative active site [active]
761193014356	catalytic triad [active]
761193014357	dimer interface [polypeptide binding]; other site
761193014358	multimer interface [polypeptide binding]; other site
761193014359	Bacillus subtilis PhoD and related proteins, metallophosphatase domain; Region: MPP_PhoD; cd07389
761193014360	putative active site [active]
761193014361	putative metal binding site [ion binding]; other site
761193014362	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
761193014363	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193014364	S-adenosylmethionine binding site [chemical binding]; other site
761193014365	diaminopimelate decarboxylase; Region: lysA; TIGR01048
761193014366	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
761193014367	active site
761193014368	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
761193014369	substrate binding site [chemical binding]; other site
761193014370	catalytic residues [active]
761193014371	dimer interface [polypeptide binding]; other site
761193014372	hypothetical protein; Provisional; Region: PRK12378
761193014373	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
761193014374	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
761193014375	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
761193014376	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
761193014377	DNA polymerase III, delta subunit; Region: holA; TIGR01128
761193014378	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
761193014379	dimer interface [polypeptide binding]; other site
761193014380	catalytic triad [active]
761193014381	gliding motility-associated lipoprotein GldB; Region: GldB_lipo; TIGR03514
761193014382	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
761193014383	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193014384	ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249
761193014385	Walker A/P-loop; other site
761193014386	ATP binding site [chemical binding]; other site
761193014387	Q-loop/lid; other site
761193014388	ABC transporter signature motif; other site
761193014389	Walker B; other site
761193014390	D-loop; other site
761193014391	H-loop/switch region; other site
761193014392	Predicted membrane protein [Function unknown]; Region: COG1950
761193014393	Helical bundle domain of the death-domain associated protein (DAXX); Region: DAXX_helical_bundle; cd13151
761193014394	DinB superfamily; Region: DinB_2; pfam12867
761193014395	Predicted alpha/beta hydrolase [General function prediction only]; Region: COG4757
761193014396	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
761193014397	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
761193014398	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
761193014399	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
761193014400	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
761193014401	active site
761193014402	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
761193014403	dimer interface [polypeptide binding]; other site
761193014404	Citrate synthase; Region: Citrate_synt; pfam00285
761193014405	active site
761193014406	citrylCoA binding site [chemical binding]; other site
761193014407	NADH binding [chemical binding]; other site
761193014408	cationic pore residues; other site
761193014409	oxalacetate/citrate binding site [chemical binding]; other site
761193014410	coenzyme A binding site [chemical binding]; other site
761193014411	catalytic triad [active]
761193014412	Domain of unknown function (DUF303); Region: DUF303; pfam03629
761193014413	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193014414	Interdomain contacts; other site
761193014415	Cytokine receptor motif; other site
761193014416	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193014417	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like2; cd05667
761193014418	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
761193014419	metal binding site [ion binding]; metal-binding site
761193014420	putative dimer interface [polypeptide binding]; other site
761193014421	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
761193014422	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193014423	active site
761193014424	motif I; other site
761193014425	motif II; other site
761193014426	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
761193014427	putative active site pocket [active]
761193014428	4-fold oligomerization interface [polypeptide binding]; other site
761193014429	metal binding residues [ion binding]; metal-binding site
761193014430	3-fold/trimer interface [polypeptide binding]; other site
761193014431	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
761193014432	Trehalase; Region: Trehalase; cl17346
761193014433	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
761193014434	Major Facilitator Superfamily; Region: MFS_1; pfam07690
761193014435	putative substrate translocation pore; other site
761193014436	Cupin domain; Region: Cupin_2; cl17218
761193014437	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
761193014438	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193014439	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
761193014440	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
761193014441	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
761193014442	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
761193014443	active site
761193014444	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
761193014445	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
761193014446	active site
761193014447	HIGH motif; other site
761193014448	dimer interface [polypeptide binding]; other site
761193014449	KMSKS motif; other site
761193014450	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
761193014451	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
761193014452	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
761193014453	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
761193014454	enoyl-CoA hydratase; Provisional; Region: PRK08140
761193014455	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
761193014456	substrate binding site [chemical binding]; other site
761193014457	oxyanion hole (OAH) forming residues; other site
761193014458	trimer interface [polypeptide binding]; other site
761193014459	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
761193014460	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
761193014461	Protein of unknown function (DUF4242); Region: DUF4242; pfam14026
761193014462	MutS domain III; Region: MutS_III; pfam05192
761193014463	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193014464	Walker A/P-loop; other site
761193014465	ATP binding site [chemical binding]; other site
761193014466	Q-loop/lid; other site
761193014467	ABC transporter signature motif; other site
761193014468	Walker B; other site
761193014469	D-loop; other site
761193014470	H-loop/switch region; other site
761193014471	Signal peptidase (SPase) II; Region: Peptidase_A8; pfam01252
761193014472	lipoprotein signal peptidase; Provisional; Region: PRK14787
761193014473	heat shock protein 90; Provisional; Region: PRK05218
761193014474	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193014475	ATP binding site [chemical binding]; other site
761193014476	Mg2+ binding site [ion binding]; other site
761193014477	G-X-G motif; other site
761193014478	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
761193014479	active site
761193014480	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193014481	Cytokine receptor motif; other site
761193014482	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
761193014483	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
761193014484	Coenzyme A binding pocket [chemical binding]; other site
761193014485	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
761193014486	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
761193014487	FAD binding pocket [chemical binding]; other site
761193014488	FAD binding motif [chemical binding]; other site
761193014489	phosphate binding motif [ion binding]; other site
761193014490	beta-alpha-beta structure motif; other site
761193014491	NAD(p) ribose binding residues [chemical binding]; other site
761193014492	NAD binding pocket [chemical binding]; other site
761193014493	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
761193014494	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
761193014495	catalytic loop [active]
761193014496	iron binding site [ion binding]; other site
761193014497	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
761193014498	FAD-linked oxidoreductase; Region: bact_FAD_ox; TIGR01679
761193014499	FAD binding domain; Region: FAD_binding_4; pfam01565
761193014500	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
761193014501	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
761193014502	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
761193014503	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
761193014504	P-loop; other site
761193014505	Magnesium ion binding site [ion binding]; other site
761193014506	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
761193014507	Magnesium ion binding site [ion binding]; other site
761193014508	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
761193014509	ParB-like nuclease domain; Region: ParB; smart00470
761193014510	KorB domain; Region: KorB; pfam08535
761193014511	Haem utilisation ChuX/HutX; Region: ChuX_HutX; cl01509
761193014512	dihydrodipicolinate reductase; Provisional; Region: PRK00048
761193014513	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
761193014514	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
761193014515	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
761193014516	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
761193014517	Catalytic site [active]
761193014518	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
761193014519	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
761193014520	Asp-box motif; other site
761193014521	BNR repeat-like domain; Region: BNR_2; pfam13088
761193014522	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
761193014523	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
761193014524	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
761193014525	butyryl-CoA:acetate CoA-transferase; Region: butyr_acet_CoA; TIGR03948
761193014526	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
761193014527	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
761193014528	NIPSNAP; Region: NIPSNAP; pfam07978
761193014529	Predicted transcriptional regulators [Transcription]; Region: COG1733
761193014530	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
761193014531	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
761193014532	active site
761193014533	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
761193014534	catalytic tetrad [active]
761193014535	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
761193014536	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
761193014537	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
761193014538	Cytochrome c; Region: Cytochrom_C; pfam00034
761193014539	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
761193014540	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
761193014541	catalytic residue [active]
761193014542	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
761193014543	four helix bundle protein; Region: TIGR02436
761193014544	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
761193014545	Dehydroquinase class II; Region: DHquinase_II; pfam01220
761193014546	active site
761193014547	trimer interface [polypeptide binding]; other site
761193014548	dimer interface [polypeptide binding]; other site
761193014549	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
761193014550	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193014551	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193014552	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193014553	starch binding outer membrane protein SusD; Region: SusD; cd08977
761193014554	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
761193014555	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193014556	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
761193014557	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
761193014558	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193014559	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
761193014560	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
761193014561	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193014562	active site
761193014563	phosphorylation site [posttranslational modification]
761193014564	intermolecular recognition site; other site
761193014565	dimerization interface [polypeptide binding]; other site
761193014566	LytTr DNA-binding domain; Region: LytTR; smart00850
761193014567	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
761193014568	Histidine kinase; Region: His_kinase; pfam06580
761193014569	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
761193014570	ATP binding site [chemical binding]; other site
761193014571	Mg2+ binding site [ion binding]; other site
761193014572	G-X-G motif; other site
761193014573	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
761193014574	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193014575	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193014576	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_4; cd06241
761193014577	putative active site [active]
761193014578	Zn binding site [ion binding]; other site
761193014579	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair]; Region: RecB; COG1074
761193014580	Family description; Region: UvrD_C_2; pfam13538
761193014581	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
761193014582	COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: sli:Slin_6331 ABC transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein
761193014583	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
761193014584	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
761193014585	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193014586	Walker A/P-loop; other site
761193014587	ATP binding site [chemical binding]; other site
761193014588	Q-loop/lid; other site
761193014589	ABC transporter signature motif; other site
761193014590	Walker B; other site
761193014591	D-loop; other site
761193014592	H-loop/switch region; other site
761193014593	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
761193014594	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
761193014595	DNA binding residues [nucleotide binding]
761193014596	thymidylate synthase; Reviewed; Region: thyA; PRK01827
761193014597	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
761193014598	dimerization interface [polypeptide binding]; other site
761193014599	active site
761193014600	TIGR02646 family protein; Region: TIGR02646
761193014601	AAA domain; Region: AAA_23; pfam13476
761193014602	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
761193014603	AAA domain; Region: AAA_21; pfam13304
761193014604	Walker A/P-loop; other site
761193014605	ATP binding site [chemical binding]; other site
761193014606	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
761193014607	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
761193014608	active site
761193014609	substrate binding site [chemical binding]; other site
761193014610	coenzyme B12 binding site [chemical binding]; other site
761193014611	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
761193014612	B12 binding site [chemical binding]; other site
761193014613	cobalt ligand [ion binding]; other site
761193014614	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Beta subunit-like subfamily; contains bacterial proteins similar to the beta subunit of MCMs from Propionbacterium shermanni and Streptomyces cinnamonensis, which are alpha/beta...; Region: MM_CoA_mutase_beta; cd03677
761193014615	heterodimer interface [polypeptide binding]; other site
761193014616	substrate interaction site [chemical binding]; other site
761193014617	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
761193014618	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
761193014619	P-loop; other site
761193014620	Magnesium ion binding site [ion binding]; other site
761193014621	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
761193014622	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
761193014623	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
761193014624	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
761193014625	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
761193014626	Domain of unknown function DUF87; Region: DUF87; pfam01935
761193014627	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
761193014628	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
761193014629	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
761193014630	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
761193014631	Conjugative transposon protein TraO; Region: TraO; pfam10626
761193014632	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
761193014633	Integrase core domain; Region: rve; pfam00665
761193014634	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
761193014635	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193014636	Walker A motif; other site
761193014637	ATP binding site [chemical binding]; other site
761193014638	Walker B motif; other site
761193014639	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
761193014640	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
761193014641	Radical SAM superfamily; Region: Radical_SAM; pfam04055
761193014642	FeS/SAM binding site; other site
761193014643	HipA-like N-terminal domain; Region: HipA_N; pfam07805
761193014644	HipA-like C-terminal domain; Region: HipA_C; pfam07804
761193014645	HipA N-terminal domain; Region: Couple_hipA; pfam13657
761193014646	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193014647	non-specific DNA binding site [nucleotide binding]; other site
761193014648	salt bridge; other site
761193014649	sequence-specific DNA binding site [nucleotide binding]; other site
761193014651	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
761193014652	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
761193014653	Domain of unknown function (DUF932); Region: DUF932; cl12129
761193014654	Initiator Replication protein; Region: Rep_3; pfam01051
761193014655	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
761193014656	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
761193014657	metal-binding site [ion binding]
761193014658	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
761193014659	Soluble P-type ATPase [General function prediction only]; Region: COG4087
761193014660	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
761193014661	metal-binding site [ion binding]
761193014662	Protein of unknown function DUF45; Region: DUF45; pfam01863
761193014663	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
761193014664	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
761193014665	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
761193014666	ATP binding site [chemical binding]; other site
761193014667	putative Mg++ binding site [ion binding]; other site
761193014668	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193014669	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
761193014670	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
761193014671	HsdM N-terminal domain; Region: HsdM_N; pfam12161
761193014672	Methyltransferase domain; Region: Methyltransf_26; pfam13659
761193014673	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
761193014674	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
761193014675	Soluble P-type ATPase [General function prediction only]; Region: COG4087
761193014676	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193014677	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193014678	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
761193014679	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
761193014680	oligomer interface [polypeptide binding]; other site
761193014681	Outer membrane efflux protein; Region: OEP; pfam02321
761193014682	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
761193014683	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
761193014684	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
761193014685	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
761193014686	motif II; other site
761193014687	PepSY-associated TM helix; Region: PepSY_TM_3; pfam13706
761193014688	SnoaL-like domain; Region: SnoaL_3; pfam13474
761193014689	Protein of unknown function (DUF3347); Region: DUF3347; pfam11827
761193014690	MerT mercuric transport protein; Region: MerT; cl03578
761193014691	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
761193014692	metal-binding site [ion binding]
761193014693	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193014694	S-adenosylmethionine binding site [chemical binding]; other site
761193014695	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
761193014696	Haem-binding domain; Region: Haem_bd; pfam14376
761193014697	Protein of unknown function (DUF3347); Region: DUF3347; pfam11827
761193014698	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193014699	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
761193014700	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193014701	Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999
761193014702	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193014703	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
761193014704	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
761193014705	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
761193014706	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
761193014707	Asp-box motif; other site
761193014708	multicopper oxidase; Provisional; Region: PRK10965
761193014709	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
761193014710	Multicopper oxidase; Region: Cu-oxidase; pfam00394
761193014711	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
761193014712	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193014713	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193014714	transcription elongation factor S-II; Region: TFSII; TIGR01385
761193014715	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
761193014716	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
761193014717	Cre recombinase, C-terminal catalytic domain. Cre-like recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The bacteriophage P1 Cre...; Region: INT_Cre; cd00799
761193014718	DNA binding site [nucleotide binding]
761193014719	dimer interface [polypeptide binding]; other site
761193014720	active site
761193014721	Int/Topo IB signature motif; other site
761193014722	Homeodomain-like domain; Region: HTH_23; pfam13384
761193014723	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3415
761193014724	Homeodomain-like domain; Region: HTH_32; pfam13565
761193014725	Winged helix-turn helix; Region: HTH_33; pfam13592
761193014726	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193014727	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
761193014728	Winged helix-turn helix; Region: HTH_29; pfam13551
761193014729	Homeodomain-like domain; Region: HTH_32; pfam13565
761193014730	DDE superfamily endonuclease; Region: DDE_3; pfam13358
761193014731	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
761193014732	active site
761193014733	NTP binding site [chemical binding]; other site
761193014734	metal binding triad [ion binding]; metal-binding site
761193014735	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
761193014736	active site
761193014737	NTP binding site [chemical binding]; other site
761193014738	metal binding triad [ion binding]; metal-binding site
761193014739	Patatin-like phospholipase; includes PNPLA8, PNPLA9, and Pat17; Region: Pat17_PNPLA8_PNPLA9_like; cd07199
761193014740	active site
761193014741	nucleophile elbow; other site
761193014742	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
761193014743	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193014744	non-specific DNA binding site [nucleotide binding]; other site
761193014745	salt bridge; other site
761193014746	sequence-specific DNA binding site [nucleotide binding]; other site
761193014747	Domain of unknown function (DUF955); Region: DUF955; cl01076
761193014748	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
761193014749	putative active site [active]
761193014750	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
761193014751	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
761193014752	metal binding site [ion binding]; metal-binding site
761193014753	active site
761193014754	I-site; other site
761193014755	Methyltransferase domain; Region: Methyltransf_26; pfam13659
761193014756	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
761193014757	DEAD-like helicases superfamily; Region: DEXDc; smart00487
761193014758	DNA methylase [Transcription / DNA replication, recombination, and repair]; Region: COG4646
761193014759	helicase superfamily c-terminal domain; Region: HELICc; smart00490
761193014760	ATP-binding site [chemical binding]; other site
761193014761	Domain of unknown function (DUF1896); Region: DUF1896; pfam08989
761193014762	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
761193014763	Peptidase family M23; Region: Peptidase_M23; pfam01551
761193014764	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
761193014765	non-specific DNA binding site [nucleotide binding]; other site
761193014766	salt bridge; other site
761193014767	sequence-specific DNA binding site [nucleotide binding]; other site
761193014768	HipA N-terminal domain; Region: couple_hipA; TIGR03071
761193014769	HipA-like N-terminal domain; Region: HipA_N; pfam07805
761193014770	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
761193014771	HipA-like C-terminal domain; Region: HipA_C; pfam07804
761193014772	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
761193014773	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
761193014774	AAA domain; Region: AAA_22; pfam13401
761193014775	Walker A motif; other site
761193014776	ATP binding site [chemical binding]; other site
761193014777	Walker B motif; other site
761193014778	arginine finger; other site
761193014779	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
761193014780	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
761193014781	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
761193014782	COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sli:Slin_6996 ATPase-like protein involved in chromosome partitioning; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Cobyrinic acid ac-diamide synthase
761193014783	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
761193014784	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
761193014785	P-loop; other site
761193014786	Magnesium ion binding site [ion binding]; other site
761193014787	Initiator Replication protein; Region: Rep_3; pfam01051
761193014788	KEGG: dfe:Dfer_0389 hypothetical protein; SPTR: Putative uncharacterized protein
761193014789	Protein of unknown function (DUF983); Region: DUF983; cl02211
761193014790	Predicted transporter component [General function prediction only]; Region: COG2391
761193014791	Sulphur transport; Region: Sulf_transp; pfam04143
761193014792	Predicted transporter component [General function prediction only]; Region: COG2391
761193014793	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
761193014794	outer membrane porin, OprD family; Region: OprD; pfam03573
761193014795	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
761193014796	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
761193014797	active site
761193014798	metal binding site [ion binding]; metal-binding site
761193014799	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
761193014800	DsrE/DsrF-like family; Region: DrsE; cl00672
761193014801	Cytochrome c [Energy production and conversion]; Region: COG3258
761193014802	Cytochrome c; Region: Cytochrom_C; pfam00034
761193014803	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193014804	S-adenosylmethionine binding site [chemical binding]; other site
761193014805	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
761193014806	S-adenosylmethionine binding site [chemical binding]; other site
761193014807	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
761193014808	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
761193014809	catalytic residues [active]
761193014810	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
761193014811	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193014812	active site residue [active]
761193014813	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193014814	active site residue [active]
761193014815	Domain of unknown function (DUF202); Region: DUF202; pfam02656
761193014816	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
761193014817	Rhodanese-like domain; Region: Rhodanese; pfam00581
761193014818	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
761193014819	active site residue [active]
761193014820	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
761193014821	Prodigal; manually curated
761193014822	KEGG: hch:HCH_05614 transposase; SPTR: Putative transposase
761193014823	Homeodomain-like domain; Region: HTH_23; pfam13384
761193014824	Winged helix-turn helix; Region: HTH_29; pfam13551
761193014825	Homeodomain-like domain; Region: HTH_32; pfam13565
761193014826	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
761193014827	Cna protein B-type domain; Region: Cna_B_2; pfam13715
761193014828	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
761193014829	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
761193014830	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
761193014831	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
761193014832	HlyD family secretion protein; Region: HlyD_3; pfam13437
761193014833	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
761193014834	Helix-turn-helix domain; Region: HTH_18; pfam12833
761193014835	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
761193014836	two-component response regulator; Provisional; Region: PRK14084
761193014837	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
761193014838	active site
761193014839	phosphorylation site [posttranslational modification]
761193014840	intermolecular recognition site; other site
761193014841	dimerization interface [polypeptide binding]; other site
761193014842	LytTr DNA-binding domain; Region: LytTR; smart00850
761193014843	Histidine kinase; Region: His_kinase; pfam06580
761193014844	COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: sus:Acid_0065 beta-lactamase; PFAM: Beta-lactamase-related; SPTR: Beta-lactamase, putative
761193014845	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
761193014846	Beta-lactamase; Region: Beta-lactamase; pfam00144
761193014847	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
761193014848	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
761193014849	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
761193014850	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
761193014851	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193014852	Interdomain contacts; other site
761193014853	Cytokine receptor motif; other site
761193014854	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
761193014855	Interdomain contacts; other site
761193014856	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
761193014857	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
761193014858	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
761193014859	catalytic residues [active]
761193014860	catalytic nucleophile [active]
761193014861	Presynaptic Site I dimer interface [polypeptide binding]; other site
761193014862	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
761193014863	Synaptic Flat tetramer interface [polypeptide binding]; other site
761193014864	Synaptic Site I dimer interface [polypeptide binding]; other site
761193014865	DNA binding site [nucleotide binding]