-- dump date 20140620_042253 -- class Genbank::CDS -- table cds_note -- id note YP_003131922.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_003131923.1 binds the polymerase to DNA and acts as a sliding clamp YP_003131924.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_003131925.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_003131926.1 PFAM: Protein of unknown function (DUF721) YP_003131927.1 PFAM: DNA gyrase B; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Toprim domain; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit YP_003131928.1 negatively supercoils closed circular double-stranded DNA YP_003131930.1 PFAM: Nucleotidyltransferase domain YP_003131934.1 PFAM: NUDIX domain YP_003131937.1 PFAM: Protein of unknown function (DUF418); Protein of unknown function (DUF405) YP_003131938.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003131939.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Histidine kinase YP_003131940.1 PFAM: Domain of unknown function (DUF2020) YP_003131943.1 PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_003131944.1 PFAM: Rhomboid family YP_003131946.1 integral membrane protein involved in inhibition of the Z-ring formation YP_003131947.1 PFAM: Sortase family; TIGRFAM: LPXTG-site transpeptidase (sortase) family protein YP_003131949.1 PFAM: Bacterial regulatory proteins, tetR family; Tetracyclin repressor, C-terminal all-alpha domain YP_003131950.1 PFAM: ABC transporter; TIGRFAM: daunorubicin resistance ABC transporter ATP-binding subunit YP_003131951.1 PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family YP_003131952.1 PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_003131953.1 PFAM: Protein kinase domain; PASTA domain YP_003131954.1 PFAM: Protein kinase domain YP_003131955.1 PFAM: Penicillin binding protein transpeptidase domain YP_003131956.1 PFAM: Cell cycle protein YP_003131957.1 PFAM: Protein phosphatase 2C YP_003131958.1 PFAM: FHA domain YP_003131959.1 PFAM: FHA domain YP_003131961.1 TIGRFAM: LPXTG-motif cell wall anchor domain YP_003131962.1 PFAM: Bacterial transcriptional activator domain; NB-ARC domain; Transcriptional regulatory protein, C terminal YP_003131963.1 PFAM: Luciferase-like monooxygenase YP_003131964.1 PFAM: HpcH/HpaI aldolase/citrate lyase family YP_003131966.1 PFAM: NAD dependent epimerase/dehydratase family YP_003131967.1 PFAM: D-arabinono-1,4-lactone oxidase; FAD binding domain; TIGRFAM: FAD-linked oxidoreductase YP_003131968.1 PFAM: Alanine racemase, N-terminal domain YP_003131969.1 PFAM: Bacterial regulatory proteins, tetR family YP_003131972.1 PFAM: Helix-turn-helix YP_003131973.1 PFAM: Phosphotransferase enzyme family YP_003131974.1 PFAM: Copper resistance protein D YP_003131975.1 PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport YP_003131976.1 PFAM: Copper resistance protein CopC YP_003131977.1 PFAM: Domain of unkown function (DUF1775) YP_003131979.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003131980.1 PFAM: ABC transporter; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit YP_003131981.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003131982.1 PFAM: Substrate binding domain of ABC-type glycine betaine transport system YP_003131985.1 PFAM: short chain dehydrogenase YP_003131986.1 PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase YP_003131987.1 PFAM: SnoaL-like polyketide cyclase YP_003131988.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: GDP-mannose 4,6-dehydratase YP_003131989.1 TIGRFAM: methyltransferase, FkbM family YP_003131990.1 PFAM: Glycosyl transferases group 1 YP_003131993.1 PFAM: Glycosyl transferases group 1 YP_003131994.1 PFAM: Flagellar basal body-associated protein FliL YP_003131997.1 PFAM: Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase YP_003131998.1 PFAM: Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_003132000.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Histidine kinase YP_003132001.1 PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type YP_003132002.1 PFAM: LytTr DNA-binding domain; Response regulator receiver domain YP_003132004.1 PFAM: Sodium:solute symporter family YP_003132005.1 PFAM: Rhodanese-like domain YP_003132007.1 PFAM: CutA1 divalent ion tolerance protein YP_003132009.1 PFAM: Protein of unknown function (DUF952) YP_003132010.1 PFAM: Sigma-70 region 2; Sigma-70, region 4; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-E family YP_003132012.1 PFAM: Ferritin-like domain YP_003132013.1 catalyzes the degradation of arginine to citruline and ammonia YP_003132015.1 PFAM: CAAX amino terminal protease family YP_003132016.1 PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport YP_003132019.1 PFAM: IclR helix-turn-helix domain YP_003132020.1 PFAM: Uncharacterized protein family UPF0016 YP_003132021.1 PFAM: Bacterial Cytochrome Ubiquinol Oxidase YP_003132022.1 PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB) YP_003132023.1 PFAM: ABC transporter transmembrane region; ABC transporter; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD YP_003132024.1 PFAM: Histidine kinase; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003132025.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003132026.1 PFAM: Substrate binding domain of ABC-type glycine betaine transport system YP_003132027.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003132028.1 PFAM: ABC transporter; CBS domain pair; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit YP_003132031.1 PFAM: Bacterial transcriptional activator domain YP_003132032.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_003132033.1 PFAM: Macro domain YP_003132034.1 PFAM: Prephenate dehydratase; ACT domain YP_003132035.1 PFAM: Major Facilitator Superfamily YP_003132036.1 PFAM: Domain of unknown function (DUF1025) YP_003132038.1 TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003132039.1 PFAM: Glutathionylspermidine synthase YP_003132040.1 PFAM: Domain of Unknown Function (DUF350) YP_003132041.1 PFAM: alpha/beta hydrolase fold YP_003132042.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003132044.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily YP_003132045.1 PFAM: Luciferase-like monooxygenase YP_003132046.1 PFAM: FAD dependent oxidoreductase; UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase YP_003132047.1 PFAM: PAP2 superfamily YP_003132048.1 PFAM: UbiA prenyltransferase family YP_003132049.1 PFAM: Mycobacterial cell wall arabinan synthesis protein YP_003132054.1 PFAM: short chain dehydrogenase YP_003132055.1 PFAM: FAD binding domain; D-arabinono-1,4-lactone oxidase YP_003132056.1 PFAM: GtrA-like protein YP_003132064.1 PFAM: Glycosyl transferase family 2 YP_003132065.1 PFAM: ABC transporter YP_003132066.1 PFAM: ABC-2 type transporter YP_003132069.1 PFAM: Acetyltransferase (GNAT) family YP_003132070.1 PFAM: NeuB family; SAF domain YP_003132071.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family YP_003132072.1 PFAM: Polysaccharide biosynthesis protein YP_003132073.1 PFAM: Cytidylyltransferase YP_003132075.1 PFAM: Protein of unknown function (DUF2587) YP_003132076.1 PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein, VC1184 subfamily YP_003132077.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain; TIGRFAM: putative NAD(P)H quinone oxidoreductase, PIG3 family YP_003132078.1 PFAM: PA domain; Peptidase family M28 YP_003132079.1 PFAM: MarR family YP_003132080.1 PFAM: Small Multidrug Resistance protein YP_003132081.1 PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator) YP_003132082.1 PFAM: Semialdehyde dehydrogenase, NAD binding domain YP_003132083.1 PFAM: Domain of unknown function (DUF955) YP_003132084.1 PFAM: Helix-turn-helix YP_003132086.1 PFAM: Glycosyl hydrolase family 3 N terminal domain YP_003132087.1 PFAM: Streptomyces sporulation and cell division protein, SsgA YP_003132089.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III YP_003132090.1 PFAM: HAMP domain; Adenylate and Guanylate cyclase catalytic domain YP_003132091.1 PFAM: Ku70/Ku80 beta-barrel domain; TIGRFAM: Ku protein, prokaryotic YP_003132092.1 TIGRFAM: DNA ligase D, 3'-phosphoesterase domain YP_003132093.1 PFAM: Sigma-70 region 2; Sigma-70, region 4; Sigma-70 region 3; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily YP_003132096.1 PFAM: Domain of unknown function DUF81 YP_003132097.1 PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase YP_003132098.1 PFAM: Dienelactone hydrolase family YP_003132102.1 PFAM: AMP-binding enzyme; TIGRFAM: acetoacetyl-CoA synthase YP_003132103.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase family YP_003132106.1 PFAM: Protein of unknown function (DUF742) YP_003132107.1 PFAM: Oxidoreductase family, C-terminal alpha/beta domain; Oxidoreductase family, NAD-binding Rossmann fold YP_003132108.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family YP_003132109.1 PFAM: NUDIX domain; TIGRFAM: mutator mutT protein YP_003132110.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_003132111.1 PFAM: Bacterial regulatory protein, arsR family YP_003132112.1 PFAM: alpha/beta hydrolase fold YP_003132113.1 PFAM: Methyltransferase domain YP_003132114.1 PFAM: Helix-turn-helix; Cupin domain YP_003132115.1 PFAM: Protein of unknown function (DUF421) YP_003132117.1 PFAM: Protein of unknown function DUF262; Divergent AAA domain; hypothetical protein (DUF2081) YP_003132120.1 PFAM: Glutamine amidotransferases class-II; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing) YP_003132121.1 PFAM: Bacterial regulatory proteins, tetR family YP_003132122.1 PFAM: Luciferase-like monooxygenase YP_003132124.1 PFAM: DUF218 domain YP_003132126.1 PFAM: MerR, DNA binding; MerR family regulatory protein YP_003132127.1 PFAM: ADP-ribosylglycohydrolase YP_003132128.1 PFAM: Spermine/spermidine synthase YP_003132129.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003132130.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Histidine kinase YP_003132131.1 PFAM: ABC-2 type transporter YP_003132132.1 PFAM: ABC transporter YP_003132134.1 PFAM: Nitrate and nitrite sensing; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003132135.1 PFAM: Roadblock/LC7 domain YP_003132136.1 PFAM: Protein of unknown function (DUF742) YP_003132137.1 PFAM: Conserved hypothetical ATP binding protein YP_003132138.1 PFAM: Methyltransferase domain YP_003132139.1 PFAM: 4Fe-4S binding domain; Cysteine-rich domain YP_003132140.1 PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain YP_003132141.1 PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD YP_003132143.1 PFAM: Cytochrome P450 YP_003132148.1 PFAM: Uncharacterized BCR, YitT family COG1284 YP_003132150.1 PFAM: Aminotransferase class I and II YP_003132151.1 PFAM: Protein of unknown function (DUF445) YP_003132152.1 PFAM: Transcriptional regulator PadR-like family YP_003132153.1 PFAM: ABC transporter YP_003132154.1 PFAM: Predicted permease YP_003132157.1 PFAM: Helix-turn-helix YP_003132159.1 PFAM: Protein of unknown function (DUF2516) YP_003132160.1 PFAM: YbaK / prolyl-tRNA synthetases associated domain YP_003132161.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_003132162.1 PFAM: Zinc-binding dehydrogenase YP_003132163.1 PFAM: Formyl transferase; Formyl transferase, C-terminal domain YP_003132165.1 PFAM: MbtH-like protein YP_003132166.1 PFAM: FecCD transport family YP_003132167.1 PFAM: FecCD transport family YP_003132168.1 PFAM: ABC transporter YP_003132169.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_003132170.1 PFAM: Protein of unknown function (DUF2505) YP_003132171.1 PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; FAD binding domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_003132172.1 PFAM: short chain dehydrogenase YP_003132173.1 PFAM: alpha/beta hydrolase fold YP_003132174.1 PFAM: Glycosyl transferases group 1; TIGRFAM: UDP-N-acetylglucosamine: 1L-myo-inositol-1-phosphate 1-alpha-D-N-acetylglucosaminyltransferase YP_003132175.1 PFAM: Protein of unknown function (DUF2596) YP_003132176.1 PFAM: Phosphoglycerate mutase family; TIGRFAM: phosphoglycerate mutase, BPG-dependent, family 1 YP_003132177.1 PFAM: His Kinase A (phosphoacceptor) domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003132178.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_003132179.1 PFAM: Ppx/GppA phosphatase family YP_003132181.1 PFAM: Xylose isomerase-like TIM barrel YP_003132182.1 PFAM: Proline dehydrogenase YP_003132184.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase YP_003132185.1 PFAM: Prophage CP4-57 regulatory protein (AlpA); TIGRFAM: DNA binding domain, excisionase family YP_003132186.1 PFAM: NAD dependent epimerase/dehydratase family YP_003132187.1 PFAM: Acyltransferase YP_003132188.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like YP_003132190.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_003132191.1 PFAM: AMP-binding enzyme YP_003132192.1 PFAM: Glutaredoxin-like domain (DUF836) YP_003132193.1 modulates transcription in response to the NADH/NAD(+) redox state YP_003132194.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_003132195.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_003132196.1 PFAM: Uroporphyrinogen-III synthase HemD; Tetrapyrrole (Corrin/Porphyrin) Methylases YP_003132197.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_003132201.1 PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase YP_003132202.1 PFAM: Phosphoglycerate mutase family YP_003132203.1 PFAM: Redoxin YP_003132204.1 PFAM: Cytochrome C biogenesis protein transmembrane region YP_003132205.1 PFAM: ResB-like family YP_003132206.1 PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB YP_003132209.1 PFAM: MerR family regulatory protein; TIGRFAM: DNA binding domain, excisionase family YP_003132211.1 PFAM: Pyridoxal-phosphate dependent enzyme YP_003132212.1 PFAM: UbiA prenyltransferase family; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_003132213.1 PFAM: AMP-binding enzyme YP_003132215.1 PFAM: Helix-turn-helix YP_003132218.1 PFAM: Enoyl-CoA hydratase/isomerase family; TIGRFAM: naphthoate synthase (dihydroxynaphthoic acid synthetase) YP_003132219.1 PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; TIGRFAM: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase YP_003132220.1 PFAM: Peptidase family M1 YP_003132222.1 PFAM: ubiE/COQ5 methyltransferase family; TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases YP_003132223.1 PFAM: FAD binding domain; TIGRFAM: geranylgeranyl reductase family YP_003132224.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_003132225.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_003132226.1 Catalyzes the transfer of electrons from NADH to quinone YP_003132227.1 Catalyzes the transfer of electrons from NADH to quinone YP_003132228.1 PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit YP_003132229.1 PFAM: SLBB domain; NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, F subunit YP_003132230.1 Catalyzes the transfer of electrons from NADH to quinone YP_003132231.1 PFAM: NADH dehydrogenase YP_003132232.1 Catalyzes the transfer of electrons from NADH to quinone YP_003132233.1 Catalyzes the transfer of electrons from NADH to quinone YP_003132234.1 Catalyzes the transfer of electrons from NADH to quinone YP_003132235.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_003132236.1 PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M YP_003132237.1 Catalyzes the transfer of electrons from NADH to quinone YP_003132238.1 PFAM: Polyprenyl synthetase YP_003132240.1 PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_003132241.1 PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain YP_003132242.1 PFAM: AsnC family YP_003132243.1 PFAM: Amidinotransferase YP_003132244.1 PFAM: ABC 3 transport family YP_003132245.1 PFAM: ABC 3 transport family YP_003132246.1 PFAM: ABC transporter YP_003132247.1 PFAM: Periplasmic solute binding protein family YP_003132248.1 PFAM: Peptidase family M48 YP_003132249.1 PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form YP_003132251.1 PFAM: Protein of unknown function (DUF520) YP_003132252.1 PFAM: Amidase YP_003132253.1 PFAM: Domain of unknown function (DUF309) YP_003132254.1 PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, subunit I YP_003132256.1 PFAM: SNARE associated Golgi protein YP_003132257.1 PFAM: GAF domain; EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_003132258.1 PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type YP_003132259.1 PFAM: Trypsin YP_003132260.1 PFAM: MaoC like domain YP_003132261.1 PFAM: MaoC like domain YP_003132262.1 PFAM: GDSL-like Lipase/Acylhydrolase YP_003132264.1 PFAM: Bacterial regulatory proteins, gntR family YP_003132265.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_003132266.1 PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial YP_003132267.1 PFAM: Transcription termination factor nusG; KOW motif; TIGRFAM: transcription termination/antitermination factor NusG YP_003132268.1 PFAM: Ribosomal protein L11, RNA binding domain; Ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11 YP_003132269.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_003132271.1 PFAM: Ribosomal protein L10 YP_003132272.1 PFAM: Ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12 YP_003132273.1 PFAM: ABC transporter YP_003132274.1 PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_003132275.1 PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_003132276.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132277.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132278.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132279.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132280.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132281.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132284.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_003132285.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_003132297.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_003132298.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_003132299.1 PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; Elongation factor G C-terminus; TIGRFAM: small GTP-binding protein domain; translation elongation factor EF-G YP_003132300.1 PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Elongation factor Tu C-terminal domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_003132301.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_003132302.1 PFAM: Ribosomal protein L3 YP_003132303.1 PFAM: Ribosomal protein L4/L1 family YP_003132304.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_003132305.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_003132306.1 PFAM: Ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle YP_003132307.1 PFAM: Ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type YP_003132308.1 PFAM: Ribosomal protein S3, C-terminal domain; KH domain; Ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type YP_003132309.1 PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle YP_003132310.1 PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29 YP_003132311.1 PFAM: Ribosomal protein S17 YP_003132312.1 PFAM: Ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle YP_003132313.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_003132314.1 PFAM: Ribosomal protein L5; ribosomal L5P family C-terminus YP_003132315.1 PFAM: Ribosomal protein S14p/S29e YP_003132316.1 PFAM: Ribosomal protein S8 YP_003132317.1 PFAM: Ribosomal protein L6 YP_003132318.1 PFAM: Ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type YP_003132319.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_003132320.1 PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle YP_003132321.1 PFAM: Ribosomal protein L15 amino terminal region; Ribosomal protein L15; TIGRFAM: ribosomal protein L15, bacterial/organelle YP_003132322.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_003132323.1 PFAM: Adenylate kinase; TIGRFAM: adenylate kinases YP_003132324.1 PFAM: metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I YP_003132325.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_003132326.1 PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type YP_003132327.1 PFAM: Ribosomal protein S13/S18 YP_003132328.1 PFAM: Ribosomal protein S11 YP_003132329.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_003132330.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_003132331.1 PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17 YP_003132332.1 PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I YP_003132338.1 PFAM: Protein of unknown function (DUF690) YP_003132339.1 PFAM: Subtilase family YP_003132340.1 PFAM: Protein of unknown function (DUF571); TIGRFAM: secretion protein snm4 YP_003132341.1 PFAM: FtsK/SpoIIIE family YP_003132342.1 PFAM: Hsp70 protein YP_003132343.1 PFAM: Proteins of 100 residues with WXG YP_003132344.1 PFAM: Proteins of 100 residues with WXG YP_003132347.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_003132348.1 PFAM: Ribosomal protein S9/S16 YP_003132349.1 PFAM: Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase YP_003132352.1 PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein YP_003132353.1 PFAM: Beta-ketoacyl synthase, N-terminal domain YP_003132358.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_003132359.1 PFAM: Carbohydrate kinase; YjeF-related protein N-terminus; TIGRFAM: yjeF C-terminal region, hydroxyethylthiazole kinase-related; yjeF N-terminal region YP_003132360.1 PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase YP_003132361.1 PFAM: Alanine racemase, N-terminal domain; Alanine racemase, C-terminal domain; TIGRFAM: alanine racemase YP_003132362.1 PFAM: alpha/beta hydrolase fold YP_003132363.1 PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein YP_003132365.1 PFAM: Glycoprotease family YP_003132366.1 PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase YP_003132367.1 PFAM: Glycoprotease family; TIGRFAM: metalloendopeptidase, putative, glycoprotease family YP_003132368.1 PFAM: Chaperonin 10 Kd subunit YP_003132369.1 PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL YP_003132370.1 PFAM: Transcription factor WhiB YP_003132372.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003132373.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_003132376.1 PFAM: IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase YP_003132377.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_003132378.1 PFAM: FAD dependent oxidoreductase YP_003132379.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_003132382.1 PFAM: PspC domain YP_003132383.1 PFAM: PspC domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003132384.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003132385.1 PFAM: Protein kinase domain YP_003132386.1 PFAM: Protein kinase domain YP_003132390.1 PFAM: Chorismate mutase type II; TIGRFAM: monofunctional chorismate mutase, high GC gram positive type YP_003132391.1 PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA YP_003132392.1 PFAM: Peptidase family M23 YP_003132394.1 catalyzes the interconversion of succinyl-CoA and succinate YP_003132395.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_003132398.1 PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent YP_003132399.1 PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_003132401.1 PFAM: Protein of unknown function, DUF606 YP_003132402.1 PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain YP_003132404.1 PFAM: GtrA-like protein YP_003132405.1 PFAM: Major Facilitator Superfamily YP_003132406.1 PFAM: Domain of unknown function (DUF1918) YP_003132407.1 Converts isocitrate to alpha ketoglutarate YP_003132411.1 PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth) YP_003132413.1 PFAM: Nuclease-related domain YP_003132424.1 PFAM: PglZ domain YP_003132426.1 PFAM: DEAD/DEAH box helicase; Helicase conserved C-terminal domain YP_003132429.1 PFAM: Uncharacterised BCR, YnfA/UPF0060 family YP_003132430.1 PFAM: Alpha amylase, C-terminal all-beta domain; Alpha amylase, catalytic domain YP_003132431.1 PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN); ribonuclease, putative YP_003132432.1 PFAM: Major Facilitator Superfamily YP_003132433.1 PFAM: D-alanyl-D-alanine carboxypeptidase YP_003132435.1 PFAM: Cellulose binding domain; Glycosyl hydrolase family 10 YP_003132436.1 TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein YP_003132437.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_003132438.1 PFAM: Succinate dehydrogenase cytochrome b subunit YP_003132439.1 PFAM: Succinate dehydrogenase cytochrome b subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit YP_003132440.1 PFAM: Basic membrane protein YP_003132441.1 PFAM: ABC transporter YP_003132442.1 PFAM: Branched-chain amino acid transport system / permease component YP_003132443.1 PFAM: Branched-chain amino acid transport system / permease component YP_003132444.1 PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric YP_003132445.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_003132447.1 catalyzes the formation of inosine from adenosine YP_003132449.1 PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_003132450.1 PFAM: Aldehyde dehydrogenase family YP_003132451.1 PFAM: Aldehyde dehydrogenase family YP_003132452.1 PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase YP_003132453.1 PFAM: Domain of unknown function (DUF1707) YP_003132454.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase YP_003132455.1 PFAM: Bacterial regulatory proteins, tetR family YP_003132457.1 PFAM: Major Facilitator Superfamily YP_003132458.1 PFAM: Protein of unknown function (DUF1396) YP_003132460.1 PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II YP_003132461.1 PFAM: Phosphorylase superfamily; TIGRFAM: inosine guanosine and xanthosine phosphorylase family; purine nucleotide phosphorylase YP_003132463.1 PFAM: MerR family regulatory protein YP_003132464.1 PFAM: Protein kinase domain YP_003132465.1 PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, heterodimeric type, beta chain; methylmalonyl-CoA mutase N-terminal domain YP_003132466.1 MDM; functions in conversion of succinate to propionate YP_003132467.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_003132470.1 PFAM: Peptidase family M20/M25/M40; TIGRFAM: amidohydrolase YP_003132471.1 PFAM: Protein of unknown function (DUF559) YP_003132472.1 PFAM: AIG2-like family YP_003132473.1 catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity YP_003132474.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_003132475.1 PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_003132476.1 PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins YP_003132477.1 PFAM: FAD dependent oxidoreductase YP_003132481.1 PFAM: Acetyltransferase (GNAT) family YP_003132482.1 PFAM: Domain of unknown function (DUF1707) YP_003132483.1 PFAM: Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme YP_003132485.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_003132487.1 PFAM: Carboxyl transferase domain YP_003132488.1 PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region YP_003132489.1 PFAM: Bacterial membrane flanked domain YP_003132490.1 PFAM: HMGL-like YP_003132495.1 PFAM: Inositol monophosphatase family; TIGRFAM: histidinol-phosphate phosphatase HisN, inositol monophosphatase family YP_003132496.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_003132497.1 PFAM: HAMP domain; His Kinase A (phosphoacceptor) domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003132498.1 PFAM: GtrA-like protein YP_003132499.1 PFAM: Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_003132500.1 PFAM: Protein of unknown function (DUF2029) YP_003132501.1 PFAM: ATP-grasp domain; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurK protein YP_003132502.1 PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein YP_003132503.1 PFAM: AMP-binding enzyme YP_003132504.1 TIGRFAM: conserved hypothetical protein TIGR03089 YP_003132505.1 PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_003132506.1 PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_003132507.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase YP_003132508.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-4-dehydrorhamnose reductase YP_003132509.1 PFAM: Glycosyl transferases group 1 YP_003132510.1 PFAM: Glycosyl transferase family 2; Glycosyl transferases group 1 YP_003132511.1 PFAM: Glycosyl transferase family 2 YP_003132512.1 PFAM: Glycosyl transferases group 1 YP_003132513.1 PFAM: Glycosyl transferases group 1 YP_003132514.1 PFAM: Glycosyl transferase family 2 YP_003132516.1 PFAM: Nucleotidyl transferase YP_003132518.1 PFAM: Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370 YP_003132519.1 PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain YP_003132520.1 PFAM: NUDIX domain YP_003132521.1 catalyzes the addition of gamma linked glutamate to 7,8-didemethyl-8-hydroxy-5-deazariboflavin coenzyme F420-0) YP_003132522.1 catalyzes the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP from actyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) YP_003132523.1 PFAM: 4Fe-4S binding domain YP_003132524.1 catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis YP_003132527.1 catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate YP_003132528.1 PFAM: Possible lysine decarboxylase; TIGRFAM: conserved hypothetical protein, DprA/Smf-related, family 1; conserved hypothetical protein, DprA/Smf-related, family 2 YP_003132529.1 PFAM: Possible lysine decarboxylase; TIGRFAM: conserved hypothetical protein, DprA/Smf-related, family 1; conserved hypothetical protein, DprA/Smf-related, family 2 YP_003132530.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_003132531.1 PFAM: Glycosyl transferase family 2 YP_003132533.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_003132534.1 PFAM: Methyladenine glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase I YP_003132535.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003132537.1 PFAM: Cytosol aminopeptidase family, N-terminal domain; Cytosol aminopeptidase family, catalytic domain YP_003132538.1 PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_003132539.1 PFAM: Major Facilitator Superfamily YP_003132540.1 PFAM: O-methyltransferase YP_003132541.1 PFAM: Sigma-70 region 2; Sigma-70, region 4; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_003132543.1 PFAM: PDZ domain (Also known as DHR or GLGF); Trypsin YP_003132544.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_003132545.1 PFAM: ParA/MinD ATPase like; Domain of unknown function DUF59 YP_003132547.1 PFAM: Bacterial extracellular solute-binding protein YP_003132548.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003132549.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003132550.1 PFAM: ABC transporter; TOBE domain YP_003132552.1 PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transport protein (corA) YP_003132553.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2332) YP_003132554.1 PFAM: NUDIX domain YP_003132556.1 PFAM: Bacterial membrane flanked domain YP_003132557.1 PFAM: PHP domain YP_003132558.1 PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427 YP_003132561.1 PFAM: alpha/beta hydrolase fold YP_003132563.1 PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_003132567.1 PFAM: Bacterial regulatory proteins, tetR family YP_003132569.1 PFAM: alpha/beta hydrolase fold YP_003132570.1 PFAM: Bacterial regulatory proteins, tetR family YP_003132571.1 PFAM: alpha/beta hydrolase fold YP_003132573.1 The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation YP_003132574.1 TIGRFAM: conserved hypothetical protein TIGR02569, Actinobacterial YP_003132575.1 PFAM: Putative esterase YP_003132576.1 PFAM: Siderophore-interacting protein; Siderophore-interacting FAD-binding domain YP_003132577.1 PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain YP_003132578.1 PFAM: UvrD/REP helicase YP_003132579.1 PFAM: UvrD/REP helicase YP_003132580.1 PFAM: TrkA-N domain; Ion channel YP_003132582.1 PFAM: Putative neutral zinc metallopeptidase YP_003132584.1 PFAM: GDSL-like Lipase/Acylhydrolase YP_003132585.1 PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16) YP_003132586.1 PFAM: Insulinase (Peptidase family M16); Peptidase M16 inactive domain YP_003132587.1 PFAM: NADH pyrophosphatase zinc ribbon domain; NUDIX domain; NADH pyrophosphatase-like rudimentary NUDIX domain YP_003132588.1 PFAM: CobD/Cbib protein YP_003132590.1 PFAM: Phosphotransferase enzyme family YP_003132591.1 PFAM: Low molecular weight phosphotyrosine protein phosphatase YP_003132592.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003132593.1 PFAM: Roadblock/LC7 domain YP_003132594.1 PFAM: Protein of unknown function (DUF742) YP_003132595.1 PFAM: Conserved hypothetical ATP binding protein YP_003132596.1 PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486 YP_003132597.1 PFAM: MarR family YP_003132598.1 PFAM: homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase YP_003132600.1 PFAM: Domain of unknown function (DUF1969); Fumarylacetoacetate (FAA) hydrolase family; TIGRFAM: fumarylacetoacetase YP_003132601.1 PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, A subunit YP_003132602.1 PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit YP_003132603.1 PFAM: Major Facilitator Superfamily YP_003132604.1 PFAM: Oxidoreductase FAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase NAD-binding domain; Cytochrome P450 YP_003132605.1 PFAM: Glycosyl hydrolase family 67 N-terminus; Glycosyl hydrolase family 67 middle domain; Glycosyl hydrolase family 67 C-terminus YP_003132606.1 PFAM: Glucuronate isomerase YP_003132607.1 PFAM: Bacterial regulatory proteins, lacI family; Periplasmic binding proteins and sugar binding domain of the LacI family YP_003132608.1 PFAM: ABC transporter; TOBE domain YP_003132609.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003132610.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003132611.1 PFAM: Mandelate racemase / muconate lactonizing enzyme, N-terminal domain; Mandelate racemase / muconate lactonizing enzyme, C-terminal domain YP_003132612.1 PFAM: pfkB family carbohydrate kinase YP_003132613.1 PFAM: SAF domain; D-galactarate dehydratase / Altronate hydrolase, C terminus YP_003132614.1 PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain YP_003132615.1 PFAM: IclR helix-turn-helix domain YP_003132616.1 PFAM: Putative zinc ribbon domain YP_003132617.1 PFAM: RNase H; Phosphoglycerate mutase family YP_003132619.1 PFAM: Methyltransferase small domain YP_003132627.1 PFAM: NlpC/P60 family YP_003132630.1 PFAM: Periplasmic binding protein YP_003132631.1 PFAM: alpha/beta hydrolase fold; TIGRFAM: proline iminopeptidase, Neisseria-type subfamily YP_003132632.1 PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_003132634.1 PFAM: Protein of unknown function (DUF664) YP_003132635.1 PFAM: Carbon-nitrogen hydrolase; NAD synthase; TIGRFAM: NAD+ synthetase YP_003132636.1 SecA2; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond to SecA2; which is non-essential and seems to play a role in secretion of a subset of proteins YP_003132637.1 PFAM: alpha/beta hydrolase fold; TAP-like protein YP_003132638.1 PFAM: Protein of unknown function (DUF1396) YP_003132639.1 PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I YP_003132640.1 PFAM: Glutamine amidotransferase class-I YP_003132641.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_003132642.1 PFAM: Thioesterase superfamily; TIGRFAM: conserved hypothetical protein TIGR00051 YP_003132643.1 PFAM: Glutamine synthetase, beta-Grasp domain; Glutamine synthetase, catalytic domain; TIGRFAM: glutamine synthetase, type I YP_003132644.1 PFAM: RDD family YP_003132646.1 PFAM: UvrD/REP helicase; HRDC domain YP_003132648.1 PFAM: AT hook motif; Transcription factor WhiB YP_003132650.1 PFAM: Methyltransferase domain YP_003132652.1 PFAM: ABC1 family YP_003132653.1 PFAM: ThiF family YP_003132654.1 PFAM: Protein of unknown function DUF45 YP_003132655.1 PFAM: Uncharacterised conserved protein (DUF2342) YP_003132656.1 PFAM: PDZ domain (Also known as DHR or GLGF) YP_003132658.1 PFAM: Uncharacterised protein family (UPF0182) YP_003132659.1 PFAM: Transcriptional regulator PadR-like family YP_003132660.1 PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2 YP_003132661.1 PFAM: ABC transporter; TIGRFAM: Type II (General) Secretory Pathway (IISP) Family protein; cell division ATP-binding protein FtsE YP_003132662.1 PFAM: Predicted permease YP_003132663.1 PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_003132664.1 PFAM: Amidohydrolase YP_003132665.1 PFAM: hypothetical protein (DUF2267) YP_003132666.1 PFAM: alpha/beta hydrolase fold YP_003132668.1 PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); ATP-dependent helicase C-terminal; TIGRFAM: ATP-dependent helicase HrpB YP_003132669.1 PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_003132670.1 PFAM: DoxX YP_003132671.1 PFAM: DSBA-like thioredoxin domain YP_003132673.1 PFAM: NlpC/P60 family YP_003132678.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_003132679.1 PFAM: Bacterial regulatory proteins, tetR family YP_003132683.1 PFAM: Helix-turn-helix YP_003132684.1 PFAM: alpha/beta hydrolase fold YP_003132685.1 PFAM: TspO/MBR family YP_003132686.1 PFAM: Acylphosphatase; HypF finger; yrdC domain; TIGRFAM: [NiFe] hydrogenase maturation protein HypF YP_003132688.1 PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB YP_003132689.1 PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA YP_003132690.1 PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE YP_003132691.1 PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD YP_003132692.1 PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF YP_003132693.1 PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase maturation protease YP_003132695.1 PFAM: SIS domain; TIGRFAM: phosphoheptose isomerase YP_003132697.1 TIGRFAM: phosphoheptose isomerase YP_003132698.1 PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA) YP_003132699.1 PFAM: Nickel-dependent hydrogenase YP_003132705.1 PFAM: Methyltransferase domain YP_003132706.1 PFAM: Transcription factor WhiB YP_003132707.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_003132708.1 PFAM: CBS domain pair YP_003132709.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B subunit, carboxyl terminus; DNA gyrase B; Toprim domain YP_003132710.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_003132713.1 PFAM: Universal stress protein family YP_003132716.1 PFAM: Domain of unknown function DUF20 YP_003132717.1 PFAM: Protein of unknown function (DUF1360) YP_003132719.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_003132720.1 PFAM: Protein of unknown function (DUF574) YP_003132721.1 PFAM: UbiA prenyltransferase family YP_003132722.1 PFAM: Cytochrome P450 YP_003132723.1 PFAM: Prenyltransferase and squalene oxidase repeat YP_003132724.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase YP_003132725.1 PFAM: FAD binding domain YP_003132726.1 PFAM: MerR family regulatory protein YP_003132731.1 PFAM: FAD dependent oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase YP_003132733.1 PFAM: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; X-Pro dipeptidyl-peptidase (S15 family); TIGRFAM: putative hydrolase, CocE/NonD family YP_003132734.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_003132735.1 PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region YP_003132736.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_003132738.1 PFAM: CobB/CobQ-like glutamine amidotransferase domain; CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: cobyrinic acid a,c-diamide synthase YP_003132739.1 PFAM: Cobalamin-5-phosphate synthase; TIGRFAM: cobalamin 5'-phosphate synthase/cobalamin synthase YP_003132740.1 PFAM: Phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_003132741.1 PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase YP_003132744.1 PFAM: FAD linked oxidases, C-terminal domain; FAD binding domain; Cysteine-rich domain YP_003132745.1 PFAM: Iron-containing alcohol dehydrogenase YP_003132746.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_003132747.1 PFAM: Initiation factor 2 subunit family; TIGRFAM: methylthioribose-1-phosphate isomerase; eIF-2B alpha/beta/delta-related uncharacterized proteins YP_003132748.1 PFAM: Major Facilitator Superfamily YP_003132749.1 PFAM: Aminotransferase class-V YP_003132750.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_003132751.1 activates fatty acids by binding to coenzyme A YP_003132752.1 PFAM: Metallo-beta-lactamase superfamily YP_003132753.1 PFAM: Carbon-nitrogen hydrolase YP_003132754.1 PFAM: Cobalamin-independent synthase, Catalytic domain YP_003132756.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_003132757.1 PFAM: Acetyltransferase (GNAT) family YP_003132759.1 PFAM: ACT domain YP_003132760.1 PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, C subunit YP_003132761.1 PFAM: Amidase; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, A subunit YP_003132762.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_003132765.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_003132769.1 PFAM: RHS Repeat; TIGRFAM: YD repeat (two copies) YP_003132771.1 PFAM: DoxX YP_003132772.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_003132774.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate YP_003132775.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_003132776.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_003132777.1 PFAM: Domain of unknown function (DUF397) YP_003132778.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_003132782.1 PFAM: Isocitrate/isopropylmalate dehydrogenase YP_003132784.1 PFAM: Acetyltransferase (GNAT) family YP_003132785.1 PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein YP_003132786.1 PFAM: Domain of unknown function (DUF2437); Fumarylacetoacetate (FAA) hydrolase family YP_003132787.1 PFAM: FAD binding domain YP_003132788.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_003132789.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; 2-haloalkanoic acid dehalogenase, type II YP_003132790.1 PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_003132791.1 PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit YP_003132792.1 PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit YP_003132794.1 PFAM: Phosphoglycerate mutase family; NUDIX domain YP_003132795.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_003132797.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_003132798.1 PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NADP oxidoreductase coenzyme F420-dependent YP_003132799.1 PFAM: Cupin domain YP_003132800.1 PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II YP_003132801.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_003132803.1 PFAM: AsnC family YP_003132804.1 PFAM: AIR synthase related protein, C-terminal domain; AIR synthase related protein, N-terminal domain; TIGRFAM: thiamine-monophosphate kinase YP_003132805.1 PFAM: Acetyltransferase (GNAT) family YP_003132806.1 PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase YP_003132807.1 PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28 YP_003132808.1 PFAM: DAK2 domain YP_003132809.1 catalyzes branch migration in Holliday junction intermediates YP_003132810.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_003132811.1 PFAM: Arginase family YP_003132812.1 PFAM: Bacterial regulatory protein, Fis family YP_003132815.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132816.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132817.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132818.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132819.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132820.1 PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_003132821.1 PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_003132822.1 PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_003132826.1 PFAM: Nitroreductase family YP_003132828.1 PFAM: Methyltransferase small domain; TIGRFAM: putative methyltransferase YP_003132829.1 PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain YP_003132831.1 PFAM: Uncharacterized ACR, COG1399 YP_003132832.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_003132833.1 PFAM: Double-stranded RNA binding motif; RNase3 domain; TIGRFAM: ribonuclease III, bacterial YP_003132834.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_003132835.1 PFAM: Transcriptional regulator PadR-like family YP_003132838.1 PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase) YP_003132840.1 PFAM: Acylphosphatase YP_003132841.1 PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: chromosome segregation protein SMC, common bacterial type; GTP-binding conserved hypothetical protein YP_003132843.1 PFAM: Sodium:solute symporter family; TIGRFAM: SSS sodium solute transporter superfamily YP_003132844.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_003132845.1 PFAM: SRP54-type protein, helical bundle domain; SRP54-type protein, GTPase domain; TIGRFAM: signal recognition particle-docking protein FtsY YP_003132846.1 PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_003132847.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma-70 factor, sigma-E family; RNA polymerase sigma factor, sigma-70 family YP_003132848.1 PFAM: Bacterial transcriptional regulator; IclR helix-turn-helix domain YP_003132849.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_003132851.1 PFAM: LamB/YcsF family YP_003132852.1 PFAM: Pyridoxamine 5'-phosphate oxidase YP_003132854.1 PFAM: Methyltransferase domain YP_003132855.1 PFAM: SRP54-type protein, GTPase domain; Signal peptide binding domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle protein YP_003132856.1 PFAM: Amidohydrolase family YP_003132857.1 PFAM: CAAX amino terminal protease family YP_003132858.1 PFAM: CAAX amino terminal protease family YP_003132859.1 PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16 YP_003132861.1 PFAM: PRC-barrel domain; RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM YP_003132862.1 PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase YP_003132863.1 PFAM: Ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type YP_003132864.1 PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_003132865.1 PFAM: Ribonuclease HII YP_003132866.1 PFAM: Protein of unknown function (DUF2469) YP_003132867.1 PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252 YP_003132868.1 PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein YP_003132869.1 PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA YP_003132870.1 PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; TIGRFAM: tyrosine recombinase XerC YP_003132871.1 PFAM: Sigma-70 region 2; Sigma-70, region 4; Sigma-70 region 3; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family YP_003132872.1 PFAM: Peptidase family M23 YP_003132873.1 PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type YP_003132874.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_003132875.1 PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase YP_003132876.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_003132877.1 PFAM: Cytidylyltransferase family YP_003132879.1 PFAM: Methyltransferase domain YP_003132880.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_003132882.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_003132883.1 PFAM: Peptidase family M50; TIGRFAM: RIP metalloprotease RseP YP_003132884.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_003132885.1 PFAM: Acetyltransferase (GNAT) family YP_003132886.1 PFAM: metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I YP_003132887.1 PFAM: short chain dehydrogenase; TIGRFAM: 3-hydroxybutyrate dehydrogenase YP_003132888.1 PFAM: Sugar (and other) transporter; TIGRFAM: metabolite-proton symporter YP_003132889.1 PFAM: GAF domain YP_003132890.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_003132891.1 PFAM: Major Facilitator Superfamily; TIGRFAM: cyanate transporter YP_003132892.1 catalyzes the reduction of mycothione or glutathione to mycothione or glutathione disulfide YP_003132893.1 PFAM: Trypsin YP_003132894.1 PFAM: Acetyltransferase (GNAT) family YP_003132895.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_003132896.1 PFAM: GlcNAc-PI de-N-acetylase YP_003132897.1 PFAM: DEAD/DEAH box helicase; Helicase conserved C-terminal domain YP_003132898.1 PFAM: FAD dependent oxidoreductase YP_003132899.1 PFAM: Protein of unknown function (DUF328) YP_003132900.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_003132903.1 PFAM: Uncharacterised protein family UPF0047; TIGRFAM: conserved hypothetical protein TIGR00149 YP_003132904.1 PFAM: Alanine dehydrogenase/PNT, N-terminal domain; Alanine dehydrogenase/PNT, C-terminal domain; TIGRFAM: NAD(P) transhydrogenase, alpha subunit YP_003132906.1 PFAM: NAD(P) transhydrogenase beta subunit YP_003132910.1 PFAM: Beta-ketoacyl synthase, C-terminal domain; Beta-ketoacyl synthase, N-terminal domain; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2 YP_003132911.1 carries the fatty acid chain in fatty acid biosynthesis YP_003132912.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III YP_003132913.1 PFAM: Acyl transferase domain YP_003132915.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_003132917.1 PFAM: AhpC/TSA family YP_003132918.1 PFAM: Putative neutral zinc metallopeptidase YP_003132921.1 PFAM: Protein phosphatase 2C YP_003132922.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_003132923.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_003132924.1 PFAM: SNARE associated Golgi protein YP_003132925.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_003132927.1 PFAM: Bacterial regulatory proteins, tetR family YP_003132928.1 PFAM: Luciferase-like monooxygenase YP_003132929.1 PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoate-protein ligase B YP_003132930.1 PFAM: PAP2 superfamily YP_003132931.1 PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: conserved hypothetical protein TIGR01777 YP_003132932.1 PFAM: e3 binding domain; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Biotin-requiring enzyme; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; 2-oxoglutarate dehydrogenase complex dihydrolipoamide succinyltransferase (E2 component) YP_003132933.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_003132935.1 PFAM: SMI1 / KNR4 family YP_003132936.1 PFAM: Cytosol aminopeptidase family, N-terminal domain; Cytosol aminopeptidase family, catalytic domain YP_003132939.1 PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II YP_003132940.1 PFAM: Phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_003132941.1 PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_003132942.1 PFAM: Aldo/keto reductase family YP_003132944.1 PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein YP_003132945.1 PFAM: Glutamine amidotransferases class-II; Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing) YP_003132946.1 PFAM: Cytochrome C oxidase subunit II, periplasmic domain; TIGRFAM: cytochrome c oxidase, subunit II YP_003132948.1 PFAM: Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: anthranilate phosphoribosyltransferase YP_003132950.1 PFAM: Cytochrome c oxidase subunit III YP_003132951.1 PFAM: Cytochrome c; TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III YP_003132952.1 PFAM: Rieske [2Fe-2S] domain YP_003132953.1 PFAM: Cytochrome b(N-terminal)/b6/petB YP_003132954.1 PFAM: AsnC family YP_003132955.1 contains 3'-5'exonuclease domain YP_003132956.1 PFAM: Protein of unknown function (DUF901) YP_003132957.1 PFAM: NlpC/P60 family YP_003132958.1 PFAM: Glycosyl transferases group 1 YP_003132960.1 PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase YP_003132961.1 TIGRFAM: dethiobiotin synthase YP_003132962.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_003132964.1 PFAM: ATP-dependent protease La (LON) domain YP_003132965.1 PFAM: NUDIX domain YP_003132966.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_003132967.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain; TIGRFAM: L-aspartate oxidase YP_003132968.1 PFAM: Quinolinate phosphoribosyl transferase, N-terminal domain; Quinolinate phosphoribosyl transferase, C-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase YP_003132969.1 PFAM: Carbon-nitrogen hydrolase YP_003132970.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_003132971.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_003132972.1 PFAM: Imidazoleglycerol-phosphate dehydratase YP_003132974.1 PFAM: MMPL family YP_003132975.1 PFAM: Bacterial regulatory proteins, tetR family YP_003132977.1 PFAM: MerR, DNA binding; MerR family regulatory protein; TIGRFAM: redox-sensitive transcriptional activator SoxR YP_003132982.1 PFAM: Pyridoxal-phosphate dependent enzyme YP_003132983.1 PFAM: Domain of unknown function (DUF385); TIGRFAM: conserved hypothetical protein TIGR00026 YP_003132984.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_003132985.1 E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component YP_003132987.1 PFAM: ABC transporter YP_003132988.1 PFAM: Branched-chain amino acid transport system / permease component YP_003132989.1 PFAM: Periplasmic binding proteins and sugar binding domain of the LacI family; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003132990.1 PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain YP_003132991.1 PFAM: Domain of Unknown Function (DUF1080); PKD domain; Carbohydrate binding module (family 6) YP_003132992.1 PFAM: Myo-inositol-1-phosphate synthase YP_003132993.1 PFAM: UbiA prenyltransferase family YP_003132994.1 PFAM: Xylose isomerase-like TIM barrel YP_003132995.1 PFAM: TatD related DNase YP_003132996.1 PFAM: Xylose isomerase-like TIM barrel YP_003132997.1 PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase YP_003132998.1 PFAM: AP endonuclease family 2 C terminus; Xylose isomerase-like TIM barrel YP_003132999.1 PFAM: Xylose isomerase-like TIM barrel YP_003133001.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_003133002.1 PFAM: CBS domain pair YP_003133003.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; TIGRFAM: nucleotide sugar dehydrogenase YP_003133004.1 PFAM: Glycosyltransferase family 9 (heptosyltransferase) YP_003133005.1 PFAM: short chain dehydrogenase YP_003133006.1 PFAM: Cytidylyltransferase; pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain II; rfaE bifunctional protein, domain I; cytidyltransferase-related domain YP_003133007.1 TIGRFAM: phosphoheptose isomerase YP_003133008.1 PFAM: Glycosyltransferase family 9 (heptosyltransferase) YP_003133009.1 PFAM: Glycosyl transferase family 2; haloacid dehalogenase-like hydrolase; TIGRFAM: histidinol-phosphate phosphatase family domain; HAD-superfamily hydrolase, subfamily IIIA; haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_003133010.1 PFAM: Carbamoyltransferase YP_003133011.1 PFAM: NAD dependent epimerase/dehydratase family YP_003133012.1 PFAM: Polysaccharide pyruvyl transferase YP_003133013.1 PFAM: Glycosyl transferase family 2 YP_003133014.1 PFAM: Glycosyl transferase family 2 YP_003133015.1 PFAM: ATPase family associated with various cellular activities (AAA); ATPase family associated with various cellular activities (AAA); C-terminal, D2-small domain, of ClpB protein YP_003133016.1 PFAM: Glycosyl transferases group 1 YP_003133017.1 PFAM: Glycosyl transferases group 1 YP_003133020.1 PFAM: Protein of unknown function (DUF1469) YP_003133023.1 PFAM: Methyltransferase small domain; TIGRFAM: HemK-related putative methylase YP_003133024.1 PFAM: Iron-binding zinc finger CDGSH type YP_003133030.1 PFAM: CBS domain pair; Peptidase family M50 YP_003133031.1 PFAM: NAD dependent epimerase/dehydratase family YP_003133032.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_003133033.1 PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_003133034.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003133035.1 PFAM: Histidine kinase YP_003133036.1 PFAM: ABC transporter YP_003133037.1 PFAM: ABC-2 type transporter YP_003133038.1 PFAM: Protein of unknown function (DUF574) YP_003133039.1 PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_003133040.1 PFAM: NUDIX domain YP_003133041.1 PFAM: Periplasmic binding proteins and sugar binding domain of the LacI family; Bacterial regulatory proteins, lacI family YP_003133042.1 PFAM: Alpha amylase, catalytic domain YP_003133043.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133044.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133045.1 PFAM: Bacterial extracellular solute-binding protein YP_003133046.1 PFAM: Putative peptidoglycan binding domain; Peptidase family M23 YP_003133047.1 PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_003133048.1 PFAM: Aminomethyltransferase folate-binding domain YP_003133049.1 PFAM: Methylenetetrahydrofolate reductase YP_003133050.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_003133051.1 PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain YP_003133052.1 PFAM: Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase; TIGRFAM: oxidoreductase alpha (molybdopterin) subunit YP_003133053.1 PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_003133056.1 PFAM: Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Copper resistance protein D YP_003133057.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_003133059.1 PFAM: Bacterial NAD-glutamate dehydrogenase YP_003133060.1 PFAM: Thioesterase superfamily; TIGRFAM: conserved hypothetical protein TIGR00051 YP_003133062.1 PFAM: Bacterial-like globin YP_003133063.1 PFAM: Mechanosensitive ion channel YP_003133064.1 PFAM: HNH endonuclease YP_003133067.1 PFAM: Domain of unknown function (DUF477) YP_003133068.1 PFAM: Peptidase family M1; TIGRFAM: aminopeptidase N, Streptomyces lividans type YP_003133069.1 PFAM: DSBA-like thioredoxin domain YP_003133070.1 PFAM: Metallo-beta-lactamase superfamily YP_003133071.1 PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase; sugar-phosphate isomerases, RpiB/LacA/LacB family YP_003133072.1 PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain YP_003133074.1 PFAM: NlpC/P60 family YP_003133075.1 PFAM: CYTH domain YP_003133080.1 PFAM: Helix-turn-helix YP_003133081.1 PFAM: Domain of unknown function (DUF397) YP_003133083.1 PFAM: Domain of unknown function (DUF397) YP_003133084.1 PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_003133085.1 PFAM: Sodium Bile acid symporter family YP_003133086.1 PFAM: Sodium:solute symporter family; TIGRFAM: SSS sodium solute transporter superfamily YP_003133087.1 PFAM: Protein of unknown function, DUF485 YP_003133088.1 PFAM: Sodium:solute symporter family YP_003133090.1 PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_003133091.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Histidine kinase YP_003133092.1 PFAM: Na+/H+ antiporter 1; TIGRFAM: Na+/H+ antiporter NhaA YP_003133093.1 PFAM: Bacterial trigger factor protein (TF); Bacterial trigger factor protein (TF) C-terminus; FKBP-type peptidyl-prolyl cis-trans isomerase; TIGRFAM: trigger factor YP_003133094.1 PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_003133095.1 PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_003133096.1 PFAM: ATPase family associated with various cellular activities (AAA); ClpX C4-type zinc finger; C-terminal, D2-small domain, of ClpB protein; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_003133100.1 PFAM: FdhD/NarQ family; TIGRFAM: formate dehydrogenase family accessory protein FdhD YP_003133102.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_003133104.1 PFAM: ABC transporter YP_003133106.1 PFAM: Branched-chain amino acid transport system / permease component YP_003133107.1 PFAM: Branched-chain amino acid transport system / permease component YP_003133109.1 PFAM: Xylose isomerase-like TIM barrel YP_003133110.1 PFAM: PKD domain; Carbohydrate binding module (family 6) YP_003133111.1 PFAM: Major Facilitator Superfamily YP_003133112.1 PFAM: Methyltransferase domain YP_003133113.1 PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_003133117.1 PFAM: Nucleoside diphosphate kinase YP_003133123.1 PFAM: ABC-2 type transporter YP_003133124.1 PFAM: Subtilase family YP_003133125.1 PFAM: Translation initiation factor IF-2, N-terminal region; S1 RNA binding domain; Ribonuclease E/G family; TIGRFAM: ribonuclease, Rne/Rng family YP_003133126.1 PFAM: Ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21 YP_003133127.1 involved in the peptidyltransferase reaction during translation YP_003133128.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_003133129.1 PFAM: Amino acid kinase family; PUA domain; TIGRFAM: glutamate 5-kinase YP_003133130.1 PFAM: Cytidylyltransferase; TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase YP_003133131.1 PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-related protein YP_003133132.1 PFAM: Phosphoglycerate mutase family YP_003133134.1 PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: degV family protein YP_003133135.1 PFAM: SLBB domain; Helix-hairpin-helix motif; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein YP_003133136.1 PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein YP_003133137.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_003133138.1 PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit YP_003133139.1 PFAM: Ribosomal protein S20; TIGRFAM: ribosomal protein S20 YP_003133140.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_003133145.1 PFAM: Methyltransferase domain YP_003133146.1 PFAM: Elongation factor G C-terminus; GTP-binding protein LepA C-terminus; Elongation factor Tu GTP binding domain; Elongation factor Tu domain 2; TIGRFAM: small GTP-binding protein domain; GTP-binding protein LepA YP_003133147.1 PFAM: 2-nitropropane dioxygenase YP_003133148.1 PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_003133150.1 PFAM: Barstar (barnase inhibitor) YP_003133151.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003133152.1 PFAM: Sodium/calcium exchanger protein YP_003133153.1 PFAM: CbiX YP_003133154.1 PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; sulfate adenylyltransferase, large subunit YP_003133155.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_003133156.1 PFAM: Phosphoadenosine phosphosulfate reductase family; TIGRFAM: phosophoadenylyl-sulfate reductase (thioredoxin); thioredoxin-dependent adenylylsulfate APS reductase YP_003133157.1 PFAM: Nitrite/Sulfite reductase ferredoxin-like half domain; Nitrite and sulphite reductase 4Fe-4S domain YP_003133158.1 PFAM: HemN C-terminal region; Radical SAM superfamily; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase YP_003133159.1 PFAM: Saccharopine dehydrogenase YP_003133161.1 PFAM: Transcription factor WhiB YP_003133163.1 PFAM: Domain of unknown function DUF YP_003133164.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_003133167.1 PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4 YP_003133168.1 PFAM: Iron-sulphur cluster biosynthesis YP_003133169.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_003133170.1 PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase YP_003133171.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_003133172.1 PFAM: Coenzyme A transferase YP_003133173.1 PFAM: Coenzyme A transferase YP_003133174.1 PFAM: Thiolase, N-terminal domain; Thiolase, C-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_003133175.1 PFAM: Dioxygenase; TIGRFAM: protocatechuate 3,4-dioxygenase, beta subunit YP_003133176.1 PFAM: Dioxygenase; TIGRFAM: protocatechuate 3,4-dioxygenase, alpha subunit YP_003133177.1 PFAM: Adenylosuccinate lyase C-terminus; Lyase; TIGRFAM: 3-carboxy-cis,cis-muconate cycloisomerase YP_003133178.1 PFAM: alpha/beta hydrolase fold; TIGRFAM: 3-oxoadipate enol-lactonase YP_003133179.1 PFAM: Carboxymuconolactone decarboxylase family; TIGRFAM: alkylhydroperoxidase AhpD family core domain; 4-carboxymuconolactone decarboxylase YP_003133180.1 PFAM: Bacterial transcriptional regulator; IclR helix-turn-helix domain; TIGRFAM: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family YP_003133182.1 PFAM: ATPase family associated with various cellular activities (AAA) YP_003133183.1 PFAM: VWA domain containing CoxE-like protein YP_003133184.1 PFAM: XdhC and CoxI family YP_003133185.1 PFAM: [2Fe-2S] binding domain; 2Fe-2S iron-sulfur cluster binding domain YP_003133186.1 PFAM: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: carbon-monoxide dehydrogenase, large subunit YP_003133187.1 PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain YP_003133188.1 PFAM: Activator of Hsp90 ATPase homolog 1-like protein YP_003133189.1 PFAM: FAD binding domain YP_003133192.1 PFAM: Sortase family; TIGRFAM: LPXTG-site transpeptidase (sortase) family protein YP_003133193.1 PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region YP_003133194.1 PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_003133195.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133196.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133197.1 PFAM: Periplasmic binding proteins and sugar binding domain of the LacI family; Bacterial regulatory proteins, lacI family YP_003133198.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_003133202.1 PFAM: Phosphoglycerate mutase family YP_003133203.1 PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_003133204.1 PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_003133205.1 PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_003133206.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_003133207.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_003133208.1 PFAM: Glycine cleavage H-protein; TIGRFAM: glycine cleavage system H protein YP_003133209.1 PFAM: Aminotransferase class I and II YP_003133210.1 PFAM: O-methyltransferase YP_003133212.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; Multidrug resistance protein YP_003133214.1 PFAM: DNA polymerase III beta subunit, central domain; MerR family regulatory protein YP_003133215.1 PFAM: FMN-dependent dehydrogenase YP_003133216.1 PFAM: Domain of unknown function (DUF1605); Helicase conserved C-terminal domain; Helicase associated domain (HA2); TIGRFAM: ATP-dependent helicase HrpA YP_003133217.1 PFAM: DNA polymerase family A YP_003133218.1 activates fatty acids by binding to coenzyme A YP_003133220.1 PFAM: Subtilase family; Peptidase inhibitor I9 YP_003133221.1 PFAM: short chain dehydrogenase YP_003133222.1 PFAM: Phosphoglycerate mutase family YP_003133223.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133224.1 PFAM: FAD dependent oxidoreductase; GMC oxidoreductase YP_003133225.1 PFAM: Siderophore-interacting protein; Siderophore-interacting FAD-binding domain YP_003133227.1 PFAM: Subtilisin inhibitor-like YP_003133228.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_003133229.1 PFAM: DnaJ C terminal region; DnaJ domain; DnaJ central domain (4 repeats); TIGRFAM: chaperone protein DnaJ YP_003133230.1 PFAM: RNA methyltransferase; TIGRFAM: conserved hypothetical protein TIGR00046 YP_003133231.1 PFAM: HIT domain YP_003133232.1 PFAM: PhoH-like protein YP_003133233.1 PFAM: Uncharacterized protein family UPF0054; TIGRFAM: conserved hypothetical protein TIGR00043 YP_003133234.1 PFAM: CBS domain pair; Domain of unknown function DUF21; Transporter associated domain YP_003133236.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_003133237.1 PFAM: RDD family YP_003133238.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_003133239.1 PFAM: Putative undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_003133241.1 PFAM: Ferric uptake regulator family YP_003133242.1 PFAM: Bacterial regulatory protein, arsR family YP_003133244.1 PFAM: Sortase family YP_003133245.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003133246.1 PFAM: DUF218 domain YP_003133247.1 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol YP_003133248.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_003133249.1 PFAM: Carboxylesterase YP_003133250.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133251.1 PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG; deoxyguanosinetriphosphate triphosphohydrolase, putative YP_003133252.1 PFAM: Serpin (serine protease inhibitor) YP_003133254.1 PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; DNA primase DnaG DnaB-binding; DnaB-helicase binding domain of primase; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core YP_003133256.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_003133258.1 PFAM: Helicase conserved C-terminal domain; TIGRFAM: CRISPR-associated helicase Cas3 YP_003133259.1 PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR-associated protein, Cse1 family YP_003133260.1 PFAM: CRISPR-associated protein Cse2 (CRISPR_cse2); TIGRFAM: CRISPR-associated protein, Cse2 family YP_003133261.1 PFAM: CT1975-like protein; TIGRFAM: CRISPR-associated protein, Cse4 family YP_003133262.1 PFAM: CRISPR-associated protein (Cas_Cas5e); TIGRFAM: CRISPR-associated protein Cas5, N-terminal domain; CRISPR-associated protein Cas5, E. coli subtype YP_003133263.1 PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein, Cse3 family YP_003133265.1 PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport YP_003133266.1 PFAM: PAP2 superfamily YP_003133267.1 PFAM: hypothetical protein (DUF2267) YP_003133270.1 PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_003133276.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_003133277.1 PFAM: Catalase-related immune-responsive; Catalase YP_003133278.1 PFAM: Penicillin amidase YP_003133282.1 PFAM: Polyketide cyclase / dehydrase and lipid transport; TIGRFAM: GTP-binding conserved hypothetical protein YP_003133283.1 PFAM: Sir2 family YP_003133284.1 PFAM: AsnC family YP_003133285.1 PFAM: Transketolase, C-terminal domain YP_003133287.1 TIGRFAM: LPXTG-motif cell wall anchor domain YP_003133289.1 PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_003133291.1 PFAM: NUDIX domain YP_003133293.1 PFAM: Helix-turn-helix YP_003133294.1 PFAM: Domain of unknown function (DUF397) YP_003133296.1 PFAM: Sodium:solute symporter family; TIGRFAM: SSS sodium solute transporter superfamily YP_003133297.1 PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1 YP_003133298.1 PFAM: Glycosyl hydrolases family 2, sugar binding domain; Glycosyl hydrolases family 2, immunoglobulin-like beta-sandwich domain YP_003133299.1 PFAM: Galactokinase galactose-binding signature; GHMP kinases N terminal domain; GHMP kinases C terminal; TIGRFAM: galactokinase YP_003133300.1 PFAM: DeoR-like helix-turn-helix domain; Bacterial regulatory proteins, deoR family YP_003133301.1 PFAM: Glutathione peroxidase YP_003133302.1 PFAM: GDSL-like Lipase/Acylhydrolase YP_003133305.1 PFAM: Sodium:neurotransmitter symporter family YP_003133306.1 PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase YP_003133309.1 PFAM: Isocitrate/isopropylmalate dehydrogenase YP_003133311.1 PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_003133313.1 PFAM: Sigma-70 factor, region 1.2; Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_003133314.1 PFAM: Metallo-beta-lactamase superfamily YP_003133315.1 PFAM: Bacterial capsule synthesis protein PGA_cap YP_003133316.1 PFAM: Bacterial membrane flanked domain YP_003133317.1 PFAM: Bacterial membrane flanked domain YP_003133321.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_003133322.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_003133323.1 PFAM: Protein of unknown function (DUF448) YP_003133324.1 PFAM: Elongation factor Tu GTP binding domain; Translation initiation factor IF-2, N-terminal region; Elongation factor Tu domain 2; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2 YP_003133325.1 PFAM: Protein of unknown function (DUF503) YP_003133326.1 PFAM: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A YP_003133329.1 PFAM: MatE; TIGRFAM: putative efflux protein, MATE family YP_003133330.1 PFAM: Major Facilitator Superfamily YP_003133331.1 PFAM: TruB family pseudouridylate synthase (N terminal domain); tRNA Pseudouridine synthase II, C terminal; TIGRFAM: tRNA pseudouridine 55 synthase YP_003133332.1 PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase YP_003133334.1 PFAM: 2',5' RNA ligase family; TIGRFAM: 2'-5' RNA ligase YP_003133335.1 PFAM: Ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle YP_003133336.1 PFAM: 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; Polyribonucleotide nucleotidyltransferase, RNA binding domain; KH domain; S1 RNA binding domain; TIGRFAM: guanosine pentaphosphate synthetase I/polynucleotide phosphorylase YP_003133337.1 PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16) YP_003133338.1 PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase YP_003133341.1 PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains YP_003133342.1 PFAM: Domain related to MnhB subunit of Na+/H+ antiporter YP_003133343.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_003133344.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_003133346.1 PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF) YP_003133347.1 PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit YP_003133348.1 PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase YP_003133349.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_003133350.1 synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_003133351.1 PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase) YP_003133352.1 PFAM: Protein of unknown function DUF75 YP_003133353.1 PFAM: Streptomyces sporulation and cell division protein, SsgA YP_003133354.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_003133355.1 PFAM: HIT domain YP_003133356.1 PFAM: YceI-like domain YP_003133357.1 PFAM: MarR family YP_003133358.1 PFAM: CDP-alcohol phosphatidyltransferase YP_003133359.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_003133360.1 PFAM: Glycosyl transferases group 1 YP_003133362.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_003133363.1 PFAM: Helix-turn-helix YP_003133364.1 PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC YP_003133365.1 PFAM: Branched-chain amino acid transport protein (AzlD) YP_003133366.1 PFAM: Domain of unknown function DUF28; TIGRFAM: conserved hypothetical protein TIGR01033 YP_003133368.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_003133369.1 PFAM: RuvA N terminal domain; RuvA, C-terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit YP_003133370.1 PFAM: Holliday junction DNA helicase ruvB C-terminus; ATPase family associated with various cellular activities (AAA); Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit YP_003133371.1 PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit YP_003133372.1 PFAM: SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecD YP_003133373.1 PFAM: SecD/SecF GG Motif; Protein export membrane protein; TIGRFAM: protein-export membrane protein SecF; protein-export membrane protein, SecD/SecF family YP_003133374.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: adenine phosphoribosyltransferase YP_003133375.1 PFAM: Region found in RelA / SpoT proteins; HD domain; ACT domain; TGS domain; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_003133376.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003133377.1 PFAM: Aminotransferase class IV YP_003133378.1 PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_003133379.1 PFAM: Metallo-beta-lactamase superfamily YP_003133381.1 PFAM: YibE/F-like protein YP_003133382.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_003133383.1 PFAM: Bacterial transcriptional regulator; IclR helix-turn-helix domain YP_003133384.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_003133385.1 PFAM: Domain of unknown function (DUF227) YP_003133386.1 PFAM: ATPase family associated with various cellular activities (AAA) YP_003133389.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003133390.1 PFAM: Uncharacterised protein family (UPF0081); TIGRFAM: conserved hypothetical protein TIGR00250 YP_003133391.1 PFAM: Aminodeoxychorismate lyase YP_003133392.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_003133393.1 PFAM: Endonuclease/Exonuclease/phosphatase family YP_003133394.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_003133395.1 PFAM: Beta-lactamase YP_003133396.1 PFAM: Dienelactone hydrolase family YP_003133397.1 PFAM: Phosphoribosyl transferase domain YP_003133399.1 PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family YP_003133400.1 PFAM: Phosphotransferase system, EIIC YP_003133401.1 PFAM: UTRA domain; Bacterial regulatory proteins, gntR family YP_003133402.1 PFAM: phosphotransferase system, EIIB YP_003133403.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; TIGRFAM: PTS system, glucose subfamily, IIA component YP_003133404.1 PFAM: Rieske [2Fe-2S] domain; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003133405.1 PFAM: Type IV leader peptidase family YP_003133406.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_003133407.1 PFAM: Shikimate kinase YP_003133408.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_003133409.1 PFAM: Dehydroquinase class II; TIGRFAM: 3-dehydroquinate dehydratase, type II YP_003133412.1 PFAM: Creatinase/Prolidase N-terminal domain; metallopeptidase family M24 YP_003133413.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_003133414.1 PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB YP_003133415.1 PFAM: Helix-turn-helix YP_003133416.1 PFAM: Phosphoribosyl transferase domain YP_003133417.1 PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase YP_003133418.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_003133420.1 PFAM: Glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain, CPSase domain; TIGRFAM: carbamoyl-phosphate synthase, small subunit YP_003133421.1 PFAM: MGS-like domain; ATP-grasp domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; carbamoyl-phosphate synthase, large subunit YP_003133422.1 PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2 YP_003133424.1 PFAM: Guanylate kinase; TIGRFAM: guanylate kinase YP_003133425.1 PFAM: RNA polymerase Rpb6; TIGRFAM: DNA-directed RNA polymerase, omega subunit YP_003133426.1 PFAM: Flavoprotein; DNA / pantothenate metabolism flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic YP_003133427.1 PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, N-terminal domain; S-adenosylmethionine synthetase, central domain; TIGRFAM: S-adenosylmethionine synthetase YP_003133428.1 PFAM: Acyltransferase family YP_003133429.1 TIGRFAM: primosomal protein N' YP_003133430.1 PFAM: Formyl transferase; Formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase YP_003133431.1 PFAM: NusB family; NOL1/NOP2/sun family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB YP_003133432.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_003133433.1 PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD YP_003133434.1 PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit YP_003133435.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate YP_003133436.1 PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_003133437.1 PFAM: Protein of unknown function (DUF2581) YP_003133438.1 PFAM: Integral membrane protein DUF6 YP_003133439.1 PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth) YP_003133440.1 PFAM: UvrB/uvrC motif; Helix-hairpin-helix motif; GIY-YIG catalytic domain; UvrC Helix-hairpin-helix N-terminal; TIGRFAM: excinuclease ABC, C subunit YP_003133441.1 PFAM: P-loop ATPase protein family YP_003133442.1 PFAM: Uncharacterised protein family UPF0052; TIGRFAM: conserved hypothetical protein, cofD-related YP_003133443.1 PFAM: Sporulation Regulator WhiA N terminal; Sporulation Regulator WhiA C terminal domain; TIGRFAM: conserved hypothetical protein YP_003133444.1 PFAM: Glycosyl transferase family 2 YP_003133448.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_003133449.1 PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_003133450.1 PFAM: Phosphoglycerate kinase YP_003133451.1 PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase YP_003133452.1 PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit YP_003133454.1 PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003133455.1 PFAM: Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: 6-phosphogluconolactonase YP_003133456.1 PFAM: Glucose-6-phosphate dehydrogenase subunit; TIGRFAM: opcA protein YP_003133457.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_003133458.1 PFAM: Phosphoglucose isomerase YP_003133459.1 PFAM: Transaldolase; TIGRFAM: transaldolase, mycobacterial type YP_003133460.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_003133461.1 converts protoheme IX and farnesyl diphosphate to heme O YP_003133462.1 PFAM: UvrD/REP helicase YP_003133463.1 PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase YP_003133464.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_003133469.1 PFAM: Fatty acid desaturase YP_003133470.1 PFAM: Cytochrome oxidase assembly protein YP_003133471.1 PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family YP_003133472.1 PFAM: ABC transporter YP_003133475.1 PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB YP_003133476.1 PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD, group 1 YP_003133477.1 PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC YP_003133478.1 PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily YP_003133479.1 PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family YP_003133480.1 PFAM: Domain of unknown function DUF59 YP_003133481.1 PFAM: Beta-lactamase YP_003133482.1 PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: phosphonate C-P lyase system protein PhnK YP_003133483.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133484.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133485.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_003133487.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain YP_003133488.1 PFAM: Prokaryotic protein of unknown function (DUF849) YP_003133489.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133490.1 PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative YP_003133492.1 PFAM: ABC transporter YP_003133495.1 PFAM: ABC transporter; ABC transporter transmembrane region YP_003133497.1 PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_003133498.1 PFAM: AhpC/TSA family YP_003133499.1 PFAM: PAS fold; GGDEF domain; EAL domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; PAS domain S-box YP_003133500.1 PFAM: Ribonucleotide reductase, small chain YP_003133501.1 Catalyzes the rate-limiting step in dNTP synthesis YP_003133502.1 PFAM: FAD dependent oxidoreductase YP_003133503.1 PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_003133504.1 PFAM: Antibiotic biosynthesis monooxygenase YP_003133505.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_003133506.1 PFAM: Acetoacetate decarboxylase (ADC) YP_003133507.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003133508.1 TIGRFAM: conserved hypothetical protein TIGR03084; uncharacterized Actinobacterial protein TIGR03083 YP_003133509.1 PFAM: Protein of unknown function (DUF1446) YP_003133510.1 PFAM: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, C-terminal domain YP_003133511.1 PFAM: Carboxyl transferase domain YP_003133512.1 PFAM: Biotin-requiring enzyme; Carbamoyl-phosphate synthase L chain, N-terminal domain; Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain YP_003133513.1 PFAM: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003133514.1 PFAM: short chain dehydrogenase YP_003133515.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133516.1 PFAM: Carbon starvation protein CstA YP_003133517.1 PFAM: Protein of unknown function (DUF466) YP_003133518.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_003133519.1 PFAM: Amino acid permease YP_003133520.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133521.1 PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases YP_003133522.1 PFAM: SIS domain YP_003133523.1 PFAM: ROK family YP_003133524.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133525.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: ATP synthase subunit 6 (eukaryotes), also subunit A (prokaryotes) YP_003133526.1 PFAM: Bacterial extracellular solute-binding protein YP_003133527.1 PFAM: Oxidoreductase family, NAD-binding Rossmann fold; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003133528.1 PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase YP_003133529.1 PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_003133530.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133531.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_003133532.1 PFAM: short chain dehydrogenase YP_003133533.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133534.1 PFAM: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, C-terminal domain YP_003133535.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003133536.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003133537.1 PFAM: Phosphotransferase enzyme family YP_003133538.1 PFAM: MaoC like domain YP_003133539.1 PFAM: short chain dehydrogenase YP_003133540.1 PFAM: DnaJ domain; Nuclease-related domain YP_003133541.1 PFAM: Conserved TM helix YP_003133543.1 PFAM: Protein kinase domain YP_003133545.1 PFAM: Calcineurin-like phosphoesterase YP_003133546.1 PFAM: Putative phospholipid-binding domain YP_003133549.1 PFAM: Aldehyde dehydrogenase family YP_003133550.1 PFAM: Phosphatidylethanolamine-binding protein; TIGRFAM: conserved hypothetical protein TIGR00481 YP_003133551.1 PFAM: AIR synthase related protein, C-terminal domain; AIR synthase related protein, N-terminal domain; TIGRFAM: selenium donor protein YP_003133552.1 PFAM: L-seryl-tRNA selenium transferase; TIGRFAM: seryl-tRNA(sec) selenium transferase YP_003133553.1 PFAM: Elongation factor Tu GTP binding domain; Elongation factor SelB, winged helix; Elongation factor Tu domain 2; TIGRFAM: selenocysteine-specific elongation factor SelB; small GTP-binding protein domain YP_003133554.1 PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_003133556.1 PFAM: NUDIX domain YP_003133558.1 PFAM: PGAP1-like protein YP_003133559.1 PFAM: ABC transporter; TOBE domain YP_003133560.1 PFAM: ROK family; MarR family YP_003133561.1 PFAM: Activator of Hsp90 ATPase homolog 1-like protein YP_003133562.1 PFAM: HIT domain YP_003133564.1 PFAM: Aminotransferase class-V YP_003133565.1 PFAM: Peptidase family M20/M25/M40 YP_003133566.1 PFAM: Ferric reductase like transmembrane component YP_003133568.1 PFAM: Protein of unknown function (DUF1696) YP_003133569.1 PFAM: Domain of unknown function (DUF1949); Uncharacterized protein family UPF0029; TIGRFAM: conserved hypothetical protein TIGR00257 YP_003133570.1 TIGRFAM: CRISPR-associated helicase Cas3 YP_003133571.1 PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR-associated protein, Cse1 family YP_003133572.1 PFAM: CRISPR-associated protein Cse2 (CRISPR_cse2); TIGRFAM: CRISPR-associated protein, Cse2 family YP_003133573.1 PFAM: CT1975-like protein; TIGRFAM: CRISPR-associated protein, Cse4 family YP_003133574.1 PFAM: CRISPR-associated protein (Cas_Cas5e); TIGRFAM: CRISPR-associated protein Cas5, Ecoli subtype; CRISPR-associated protein Cas5, N-terminal domain YP_003133575.1 PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein, Cse3 family YP_003133576.1 PFAM: Protein of unknown function DUF48; TIGRFAM: CRISPR-associated protein Cas1 YP_003133577.1 PFAM: CRISPR-associated protein (Cas_Cas2CT1978); TIGRFAM: CRISPR-associated protein Cas2, E. coli subfamily YP_003133581.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2220) YP_003133584.1 PFAM: CRISPR-associated protein (Cas_Cas2CT1978); TIGRFAM: CRISPR-associated protein Cas2, E. coli subfamily YP_003133585.1 PFAM: Protein of unknown function DUF48; TIGRFAM: CRISPR-associated protein Cas1 YP_003133586.1 PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein, Cse3 family YP_003133587.1 PFAM: CRISPR-associated protein (Cas_Cas5e); TIGRFAM: CRISPR-associated protein Cas5, N-terminal domain; CRISPR-associated protein Cas5, Ecoli subtype YP_003133588.1 PFAM: CT1975-like protein; TIGRFAM: CRISPR-associated protein, Cse4 family YP_003133589.1 PFAM: CRISPR-associated protein Cse2 (CRISPR_cse2); TIGRFAM: CRISPR-associated protein, Cse2 family YP_003133590.1 PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR-associated protein, Cse1 family YP_003133591.1 PFAM: Helicase conserved C-terminal domain; TIGRFAM: CRISPR-associated helicase Cas3 YP_003133592.1 PFAM: Transposase DDE domain YP_003133596.1 PFAM: Helix-turn-helix YP_003133598.1 PFAM: Peptidase family S58 YP_003133599.1 PFAM: IclR helix-turn-helix domain YP_003133600.1 PFAM: CoA-transferase family III YP_003133601.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003133602.1 PFAM: CBS domain pair YP_003133604.1 PFAM: Amidase YP_003133605.1 PFAM: Phosphopantetheine attachment site YP_003133606.1 PFAM: AMP-binding enzyme YP_003133609.1 PFAM: AMP-binding enzyme YP_003133611.1 PFAM: short chain dehydrogenase YP_003133612.1 catalyzes the formation of precorrin 6x from precorrin 5 YP_003133613.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_003133615.1 PFAM: ABC transporter YP_003133616.1 PFAM: FecCD transport family YP_003133617.1 PFAM: Periplasmic binding protein YP_003133618.1 PFAM: Nitrite/Sulfite reductase ferredoxin-like half domain YP_003133619.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_003133620.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase YP_003133621.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase YP_003133622.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit YP_003133623.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_003133624.1 PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase YP_003133625.1 PFAM: CobD/Cbib protein; TIGRFAM: cobalamin biosynthesis protein CobD YP_003133626.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase YP_003133627.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_003133628.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_003133629.1 PFAM: von Willebrand factor type A domain YP_003133630.1 PFAM: Acetyltransferase (GNAT) family YP_003133631.1 PFAM: short chain dehydrogenase YP_003133633.1 PFAM: Cytochrome P450 YP_003133634.1 PFAM: 2Fe-2S iron-sulfur cluster binding domain YP_003133635.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_003133636.1 PFAM: Aldehyde dehydrogenase family YP_003133637.1 PFAM: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, C-terminal domain YP_003133638.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003133639.1 PFAM: Domain of unknown function DUF35 YP_003133641.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003133642.1 PFAM: Phosphotransferase enzyme family YP_003133643.1 PFAM: short chain dehydrogenase YP_003133644.1 PFAM: short chain dehydrogenase YP_003133645.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_003133646.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133647.1 PFAM: EthD protein; TIGRFAM: conserved hypothetical protein YP_003133648.1 PFAM: Metallo-beta-lactamase superfamily YP_003133650.1 PFAM: Thiolase, N-terminal domain; Thiolase, C-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_003133651.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003133652.1 PFAM: pfkB family carbohydrate kinase YP_003133653.1 PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin YP_003133654.1 PFAM: ADP-ribosylglycohydrolase YP_003133655.1 PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_003133656.1 PFAM: ABC-2 type transporter YP_003133657.1 PFAM: ABC transporter YP_003133658.1 PFAM: Bacterial regulatory protein, arsR family YP_003133659.1 PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_003133660.1 TIGRFAM: conserved hypothetical protein YP_003133661.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_003133662.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, TIGR02957 family YP_003133663.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133664.1 PFAM: ABC transporter YP_003133666.1 PFAM: Taurine catabolism dioxygenase TauD, TfdA family YP_003133667.1 PFAM: Bacterial transferase hexapeptide (three repeats) YP_003133670.1 PFAM: Subtilase family YP_003133672.1 PFAM: DSBA-like thioredoxin domain YP_003133674.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_003133675.1 PFAM: YCII-related domain YP_003133676.1 PFAM: Major Facilitator Superfamily YP_003133681.1 PFAM: SnoaL-like polyketide cyclase YP_003133683.1 PFAM: SNARE associated Golgi protein YP_003133684.1 PFAM: ABC-2 type transporter YP_003133685.1 PFAM: ABC transporter; TIGRFAM: daunorubicin resistance ABC transporter ATP-binding subunit YP_003133686.1 PFAM: AMP-binding enzyme YP_003133687.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003133688.1 PFAM: Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, C-terminal domain YP_003133689.1 PFAM: Phosphopantetheine attachment site YP_003133690.1 PFAM: Condensation domain; AMP-binding enzyme; TIGRFAM: non-ribosomal peptide synthase domain TIGR01720; amino acid adenylation domain YP_003133691.1 PFAM: Condensation domain; AMP-binding enzyme; TIGRFAM: non-ribosomal peptide synthase domain TIGR01720; amino acid adenylation domain YP_003133692.1 PFAM: Thioesterase domain; Condensation domain; AMP-binding enzyme; TIGRFAM: amino acid adenylation domain YP_003133693.1 PFAM: MbtH-like protein YP_003133694.1 PFAM: Methyltransferase domain YP_003133695.1 PFAM: Tryptophan 2,3-dioxygenase YP_003133697.1 PFAM: Thioesterase domain YP_003133698.1 PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_003133699.1 PFAM: Citrate transporter; TIGRFAM: citrate transporter, CitMHS family YP_003133700.1 PFAM: Protein of unknown function (DUF1446) YP_003133702.1 PFAM: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; X-Pro dipeptidyl-peptidase (S15 family); TIGRFAM: putative hydrolase, CocE/NonD family YP_003133706.1 PFAM: MazG nucleotide pyrophosphohydrolase domain YP_003133709.1 PFAM: MmgE/PrpD family YP_003133710.1 PFAM: Putative cyclase YP_003133711.1 PFAM: HpcH/HpaI aldolase/citrate lyase family YP_003133713.1 PFAM: Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain; Oxidoreductase FAD-binding domain YP_003133714.1 PFAM: alpha/beta hydrolase fold YP_003133715.1 PFAM: FAD binding domain YP_003133716.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_003133717.1 PFAM: Phosphotransferase enzyme family YP_003133718.1 PFAM: short chain dehydrogenase YP_003133719.1 PFAM: Peptidase family M28; PA domain YP_003133720.1 PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein YP_003133722.1 PFAM: Sugar (and other) transporter YP_003133723.1 PFAM: Bacterial transcriptional regulator; IclR helix-turn-helix domain YP_003133724.1 PFAM: Rieske [2Fe-2S] domain YP_003133725.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_003133726.1 PFAM: Rieske [2Fe-2S] domain YP_003133727.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain; TIGRFAM: mycothiol-dependent formaldehyde dehydrogenase YP_003133728.1 PFAM: Metallo-beta-lactamase superfamily YP_003133729.1 PFAM: Beta-eliminating lyase YP_003133730.1 PFAM: FAD dependent oxidoreductase; TIGRFAM: sarcosine oxidase, beta subunit family, heterotetrameric form YP_003133731.1 PFAM: Sarcosine oxidase, delta subunit family; TIGRFAM: sarcosine oxidase, delta subunit family, heterotetrameric form YP_003133732.1 PFAM: FAD dependent oxidoreductase; Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: sarcosine oxidase, alpha subunit family, heterotetrameric form YP_003133733.1 PFAM: Sarcosine oxidase, gamma subunit family; TIGRFAM: sarcosine oxidase, gamma subunit family, heterotetrameric form YP_003133734.1 PFAM: FAD dependent oxidoreductase; Glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain YP_003133735.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_003133736.1 PFAM: Serine dehydratase beta chain; Serine dehydratase alpha chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form YP_003133737.1 PFAM: Formyl transferase; ACT domain; TIGRFAM: formyltetrahydrofolate deformylase YP_003133738.1 PFAM: Fumarylacetoacetate (FAA) hydrolase family; Domain of unknown function (DUF1969); TIGRFAM: fumarylacetoacetase YP_003133740.1 PFAM: homogentisate 1,2-dioxygenase; TIGRFAM: homogentisate 1,2-dioxygenase YP_003133741.1 PFAM: GAF domain; Transcriptional regulatory protein, C terminal YP_003133742.1 PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, A subunit YP_003133743.1 PFAM: Coenzyme A transferase; TIGRFAM: 3-oxoacid CoA-transferase, B subunit YP_003133744.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_003133745.1 PFAM: MarR family YP_003133746.1 PFAM: Metallo-beta-lactamase superfamily YP_003133747.1 PFAM: FAD binding domain YP_003133748.1 PFAM: Luciferase-like monooxygenase YP_003133749.1 PFAM: Major Facilitator Superfamily YP_003133751.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133752.1 PFAM: Metallo-beta-lactamase superfamily YP_003133753.1 PFAM: Domain of unknown function (DUF336) YP_003133754.1 PFAM: Molybdopterin oxidoreductase Fe4S4 domain; Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain YP_003133756.1 PFAM: PaaX-like protein C-terminal domain; PaaX-like protein YP_003133757.1 PFAM: Major Facilitator Superfamily YP_003133758.1 PFAM: Cys/Met metabolism PLP-dependent enzyme YP_003133760.1 PFAM: Aldo/keto reductase family YP_003133761.1 PFAM: hypothetical protein (DUF2267) YP_003133762.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133763.1 PFAM: FAD binding domain YP_003133764.1 PFAM: Phage integrase family YP_003133765.1 PFAM: Polysulphide reductase, NrfD YP_003133766.1 PFAM: 4Fe-4S binding domain YP_003133767.1 PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: formate dehydrogenase, alpha subunit, proteobacterial-type YP_003133768.1 PFAM: Acetyltransferase (GNAT) family YP_003133769.1 PFAM: Muconolactone delta-isomerase; TIGRFAM: muconolactone delta-isomerase YP_003133770.1 PFAM: Catechol dioxygenase N terminus; Dioxygenase; TIGRFAM: catechol 1,2-dioxygenase, Actinobacterial YP_003133771.1 PFAM: short chain dehydrogenase YP_003133772.1 PFAM: Bacterial regulatory proteins, luxR family YP_003133773.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_003133775.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133778.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133781.1 PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_003133782.1 PFAM: YCII-related domain YP_003133783.1 PFAM: Protein of unknown function (DUF1275) YP_003133785.1 PFAM: LysE type translocator YP_003133786.1 PFAM: Putative peptidoglycan binding domain; Domain of unknown function (DUF1906) YP_003133790.1 PFAM: Major Facilitator Superfamily YP_003133793.1 PFAM: Cytochrome P450 YP_003133795.1 PFAM: Bacterial regulatory protein, arsR family YP_003133796.1 PFAM: Sulfate transporter family; STAS domain; TIGRFAM: high affinity sulphate transporter 1 YP_003133797.1 PFAM: Alpha-lytic protease prodomain; Trypsin YP_003133799.1 PFAM: Alpha/beta hydrolase of unknown function (DUF1023) YP_003133801.1 PFAM: Protein phosphatase 2C; MerR family regulatory protein YP_003133802.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_003133803.1 PFAM: N-acetyltransferase YP_003133804.1 PFAM: Major Facilitator Superfamily YP_003133805.1 PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_003133806.1 PFAM: Transposase YP_003133807.1 PFAM: Methyltransferase domain YP_003133808.1 PFAM: Bacterial regulatory protein, arsR family YP_003133809.1 PFAM: haloacid dehalogenase-like hydrolase; E1-E2 ATPase; TIGRFAM: heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_003133810.1 PFAM: Phage integrase family YP_003133811.1 PFAM: Amidohydrolase family; WD40-like Beta Propeller Repeat; Dipeptidyl peptidase IV (DPP IV) N-terminal region YP_003133812.1 PFAM: Carbon-nitrogen hydrolase YP_003133813.1 PFAM: Acetamidase/Formamidase family YP_003133814.1 PFAM: Putative regulatory protein (CxxC_CxxC_SSSS); TIGRFAM: putative regulatory protein, FmdB family YP_003133815.1 PFAM: Phage integrase family; Phage integrase, N-terminal SAM-like domain YP_003133817.1 PFAM: Glycerophosphoryl diester phosphodiesterase family YP_003133818.1 PFAM: YeeE/YedE family (DUF395) YP_003133819.1 PFAM: SirA-like protein YP_003133821.1 PFAM: YCII-related domain YP_003133822.1 PFAM: GDSL-like Lipase/Acylhydrolase YP_003133823.1 PFAM: SPFH domain / Band 7 family YP_003133824.1 PFAM: NfeD-like YP_003133826.1 PFAM: Phosphatidylinositol 3- and 4-kinase YP_003133828.1 PFAM: Prolyl oligopeptidase family YP_003133829.1 PFAM: LD-carboxypeptidase YP_003133830.1 PFAM: Methyltransferase domain YP_003133831.1 PFAM: Pyridoxamine 5'-phosphate oxidase YP_003133832.1 TIGRFAM: carotene biosynthesis associated membrane protein YP_003133833.1 PFAM: Oligopeptide/dipeptide transporter, C-terminal region; ABC transporter; TIGRFAM: phosphonate C-P lyase system protein PhnK YP_003133834.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133835.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003133836.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_003133837.1 PFAM: D-aminopeptidase YP_003133838.1 PFAM: Peptidase family M20/M25/M40 YP_003133840.1 catalyzes the oxidation of malate to oxaloacetate YP_003133843.1 PFAM: Integral membrane protein (intg_mem_TP0381); TIGRFAM: conserved hypothetical integral membrane protein TIGR02206 YP_003133844.1 PFAM: Peptidase family M3 YP_003133845.1 PFAM: Phosphoglycerate mutase family YP_003133846.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_003133847.1 PFAM: Luciferase-like monooxygenase YP_003133848.1 PFAM: Aldo/keto reductase family YP_003133851.1 PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_003133853.1 PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain YP_003133854.1 PFAM: [2Fe-2S] binding domain; 2Fe-2S iron-sulfur cluster binding domain YP_003133855.1 PFAM: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; TIGRFAM: carbon-monoxide dehydrogenase, large subunit YP_003133857.1 PFAM: Flavin containing amine oxidoreductase YP_003133858.1 PFAM: NAD dependent epimerase/dehydratase family YP_003133859.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_003133860.1 PFAM: Sodium Bile acid symporter family; TIGRFAM: bile acid transporter YP_003133863.1 PFAM: Amylo-alpha-1,6-glucosidase YP_003133864.1 PFAM: Glycosyl transferases group 1 YP_003133866.1 PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA ligase D; DNA polymerase LigD, ligase domain YP_003133867.1 PFAM: Protein of unknown function (DUF574) YP_003133868.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_003133870.1 PFAM: Aldehyde dehydrogenase family YP_003133871.1 PFAM: Demethylmenaquinone methyltransferase; TIGRFAM: RraA famliy YP_003133872.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133873.1 PFAM: NADPH-dependent FMN reductase YP_003133874.1 PFAM: Amino acid permease YP_003133875.1 PFAM: Uncharacterized protein conserved in bacteria (DUF2236) YP_003133876.1 PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003133877.1 PFAM: PhoD-like phosphatase; TAT (twin-arginine translocation) pathway signal sequence; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003133878.1 molecular chaperone YP_003133880.1 PFAM: SpoOM protein YP_003133882.1 PFAM: UbiA prenyltransferase family YP_003133883.1 PFAM: Methyltransferase domain; TIGRFAM: ubiquinone biosynthesis O-methyltransferase YP_003133884.1 PFAM: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, C-terminal domain YP_003133885.1 PFAM: Chalcone and stilbene synthases, N-terminal domain; Chalcone and stilbene synthases, C-terminal domain YP_003133886.1 PFAM: Ferric uptake regulator family YP_003133887.1 PFAM: Catalase-related immune-responsive; Catalase YP_003133888.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase YP_003133889.1 PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_003133890.1 PFAM: ArsC family; TIGRFAM: arsenate reductase (glutaredoxin) YP_003133892.1 PFAM: RAMP superfamily YP_003133894.1 PFAM: RAMP superfamily YP_003133896.1 PFAM: RAMP superfamily YP_003133898.1 PFAM: Domain of unknown function (DUF397) YP_003133899.1 PFAM: Helix-turn-helix YP_003133902.1 PFAM: Domain of unknown function (DUF397) YP_003133903.1 PFAM: Helix-turn-helix YP_003133907.1 PFAM: Nucleotidyltransferase domain YP_003133908.1 TIGRFAM: uncharacterized Actinobacterial protein TIGR03083 YP_003133909.1 PFAM: Fumarylacetoacetate (FAA) hydrolase family YP_003133910.1 PFAM: Cupin domain; TIGRFAM: gentisate 1,2-dioxygenase YP_003133911.1 PFAM: FAD binding domain YP_003133912.1 PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_003133914.1 PFAM: OsmC-like protein YP_003133915.1 PFAM: Amino acid permease YP_003133916.1 PFAM: short chain dehydrogenase YP_003133917.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_003133918.1 PFAM: AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; non-ribosomal peptide synthase domain TIGR01720 YP_003133919.1 PFAM: ABC transporter YP_003133920.1 PFAM: FecCD transport family YP_003133921.1 PFAM: FecCD transport family YP_003133922.1 PFAM: Periplasmic binding protein YP_003133923.1 PFAM: Siderophore-interacting protein; Siderophore-interacting FAD-binding domain YP_003133924.1 PFAM: Phosphopantetheine attachment site YP_003133925.1 PFAM: Isochorismatase family YP_003133926.1 PFAM: AMP-binding enzyme; TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase YP_003133927.1 PFAM: chorismate binding enzyme; TIGRFAM: isochorismate synthases YP_003133928.1 PFAM: Purine catabolism regulatory protein-like family YP_003133929.1 PFAM: Permease family; TIGRFAM: uracil-xanthine permease YP_003133930.1 PFAM: CO dehydrogenase flavoprotein C-terminal domain; FAD binding domain in molybdopterin dehydrogenase YP_003133931.1 PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain YP_003133932.1 PFAM: Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain YP_003133933.1 PFAM: Carbon monoxide dehydrogenase subunit G (CoxG) YP_003133934.1 PFAM: Hydantoinase/oxoprolinase N-terminal region; Hydantoinase/oxoprolinase YP_003133935.1 PFAM: Hydantoinase B/oxoprolinase YP_003133937.1 PFAM: Amidohydrolase ring-opening protein (Amido_AtzD_TrzD); TIGRFAM: ring-opening amidohydrolases YP_003133938.1 PFAM: Amidase YP_003133939.1 PFAM: Calcineurin-like phosphoesterase YP_003133940.1 PFAM: Bacterial regulatory proteins, tetR family YP_003133941.1 PFAM: Amidase YP_003133942.1 PFAM: Acyltransferase family YP_003133943.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_003133945.1 PFAM: Uncharacterised BCR, YbaB family COG0718 YP_003133949.1 PFAM: Aminotransferase class-V YP_003133950.1 PFAM: Ankyrin repeat YP_003133951.1 PFAM: Catalase; Catalase-related immune-responsive YP_003133952.1 PFAM: Ferric uptake regulator family YP_003133957.1 PFAM: Multicopper oxidase; Multicopper oxidase YP_003133958.1 PFAM: Multicopper oxidase; Multicopper oxidase; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003133959.1 PFAM: Domain of Unknown Function (DUF1080); PKD domain YP_003133960.1 PFAM: Copper binding proteins, plastocyanin/azurin family; HYR domain YP_003133961.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: alkyl hydroperoxide reductase, F subunit; thioredoxin-disulfide reductase YP_003133962.1 PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family; TIGRFAM: peroxiredoxin YP_003133963.1 PFAM: Transcriptional regulatory protein, C terminal; GAF domain YP_003133964.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_003133965.1 PFAM: Zinc carboxypeptidase YP_003133966.1 PFAM: Ferric uptake regulator family YP_003133967.1 PFAM: FecCD transport family YP_003133968.1 PFAM: Periplasmic binding protein YP_003133969.1 PFAM: ABC transporter YP_003133970.1 PFAM: BioY family YP_003133972.1 PFAM: FAD dependent oxidoreductase YP_003133973.1 PFAM: Bacterial transcriptional regulator; IclR helix-turn-helix domain YP_003133974.1 PFAM: Dehydrogenase E1 component YP_003133975.1 PFAM: Transketolase, pyrimidine binding domain; Transketolase, C-terminal domain YP_003133976.1 PFAM: Biotin-requiring enzyme YP_003133978.1 PFAM: Acetamidase/Formamidase family YP_003133979.1 PFAM: Ankyrin repeat YP_003133982.1 PFAM: Domain of unknown function (DUF1990) YP_003133983.1 PFAM: Amino acid permease YP_003133984.1 PFAM: Protein of unknown function (DUF540) YP_003133985.1 PFAM: Acetone carboxylase gamma subunit YP_003133987.1 PFAM: Penicillin amidase YP_003133988.1 PFAM: Ethanolamine ammonia lyase large subunit (EutB) YP_003133989.1 catalyzes the formation of acetaldehyde from ethanolamine YP_003133990.1 PFAM: Amidohydrolase family YP_003133992.1 PFAM: Resolvase, N terminal domain; Helix-turn-helix domain of resolvase YP_003133995.1 PFAM: ABC transporter YP_003133997.1 PFAM: Transposase DDE domain YP_003133999.1 PFAM: Amino acid permease YP_003134000.1 PFAM: Methyltransferase domain YP_003134001.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_003134002.1 PFAM: Citrate transporter YP_003134003.1 activates fatty acids by binding to coenzyme A YP_003134004.1 PFAM: Carboxyl transferase domain YP_003134005.1 PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein YP_003134006.1 PFAM: Acetyltransferase (GNAT) family YP_003134007.1 PFAM: Protein of unknown function, DUF488 YP_003134008.1 PFAM: Cupin domain YP_003134009.1 PFAM: Protein of unknown function (DUF421) YP_003134010.1 PFAM: Major Facilitator Superfamily YP_003134011.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_003134013.1 PFAM: Glycosyl transferase family 2 YP_003134014.1 TIGRFAM: apolipoprotein N-acyltransferase YP_003134015.1 PFAM: Amidohydrolase family YP_003134016.1 PFAM: Radical SAM superfamily; TIGRFAM: KamA family protein YP_003134017.1 PFAM: Predicted permease YP_003134018.1 PFAM: ABC transporter YP_003134019.1 PFAM: ABC transporter YP_003134020.1 PFAM: haloacid dehalogenase-like hydrolase YP_003134022.1 PFAM: AsnC family YP_003134023.1 PFAM: Creatinase/Prolidase N-terminal domain; metallopeptidase family M24 YP_003134024.1 PFAM: 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, C-terminal SAM fold YP_003134028.1 PFAM: DEAD/DEAH box helicase; Helicase conserved C-terminal domain; DSHCT (NUC185) domain YP_003134029.1 PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: conserved protein of unknown function cotranscribed with Bmr (bmrU) YP_003134030.1 PFAM: Sec-independent protein translocase protein (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC YP_003134031.1 PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_003134034.1 PFAM: Actinomycetales protein of unknown function, DUF275; Putative proteasome component YP_003134035.1 PFAM: Diacylglycerol kinase catalytic domain; PAP2 superfamily YP_003134036.1 PFAM: MOSC N-terminal beta barrel domain; MOSC domain YP_003134037.1 PFAM: Proteasome A-type and B-type YP_003134038.1 PFAM: Proteasome A-type and B-type YP_003134039.1 PFAM: Protein of unknown function (DUF797) YP_003134040.1 PFAM: Actinomycetales protein of unknown function, DUF275; Putative proteasome component YP_003134041.1 PFAM: Aldo/keto reductase family YP_003134043.1 PFAM: ATPase family associated with various cellular activities (AAA) YP_003134047.1 PFAM: tRNA methyltransferase complex GCD14 subunit YP_003134048.1 PFAM: Peptidase family M50 YP_003134051.1 PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_003134052.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_003134053.1 PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphatase; phosphoribosyl-ATP pyrophosphohydrolase YP_003134055.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_003134057.1 PFAM: Protein of unknown function DUF75 YP_003134058.1 PFAM: Calcineurin-like phosphoesterase YP_003134059.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_003134060.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134061.1 PFAM: Cytochrome P450 YP_003134062.1 PFAM: Subtilase family YP_003134063.1 PFAM: Clp amino terminal domain YP_003134065.1 PFAM: ATPase family associated with various cellular activities (AAA) YP_003134067.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_003134068.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_003134069.1 PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase YP_003134070.1 PFAM: SpoU rRNA Methylase family; TIGRFAM: rRNA methylase, putative, group 2 YP_003134071.1 PFAM: von Willebrand factor type A domain YP_003134072.1 PFAM: Protein of unknown function DUF58 YP_003134073.1 PFAM: ATPase family associated with various cellular activities (AAA) YP_003134076.1 PFAM: Flagellar basal body-associated protein FliL YP_003134077.1 PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase 1 YP_003134078.1 PFAM: Domain of unknown function DUF81 YP_003134079.1 PFAM: hypothetical protein (DUF2260); TIGRFAM: probable methyltransferase YP_003134080.1 TIGRFAM: conserved hypothetical protein TIGR03442 YP_003134081.1 PFAM: Domain of unknown function (DUF323); TIGRFAM: conserved hypothetical protein TIGR03440 YP_003134082.1 PFAM: Glutamate-cysteine ligase family 2(GCS2); TIGRFAM: glutamate--cysteine ligase family protein YP_003134083.1 PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_003134084.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase YP_003134085.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134086.1 PFAM: CBS domain pair; Domain of unknown function DUF21; Transporter associated domain YP_003134087.1 PFAM: Domain of unknown function DUF21; CBS domain pair YP_003134091.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134092.1 PFAM: Uncharacterised ACR, COG1259 YP_003134093.1 PFAM: MerR family regulatory protein YP_003134094.1 PFAM: FHA domain YP_003134095.1 PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_003134097.1 PFAM: AMP-binding enzyme YP_003134098.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_003134099.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase, N-terminal domain YP_003134100.1 PFAM: Ankyrin repeat YP_003134101.1 PFAM: Aminotransferase class-V YP_003134102.1 PFAM: Major Facilitator Superfamily YP_003134103.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134104.1 catalyzes the interconversion of D-xylose to D-xylulose YP_003134105.1 PFAM: ROK family YP_003134106.1 PFAM: Periplasmic binding protein YP_003134107.1 PFAM: Cytochrome P450 YP_003134108.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134109.1 PFAM: Protein of unknown function (DUF1271) YP_003134110.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_003134111.1 PFAM: Cytochrome P450 YP_003134112.1 PFAM: Protein of unknown function (DUF1271) YP_003134113.1 PFAM: short chain dehydrogenase YP_003134114.1 catalyzes the formation of acetate from pyruvate YP_003134115.1 PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; Globin YP_003134116.1 PFAM: Transcriptional regulator; TIGRFAM: rrf2 family protein (putative transcriptional regulator) YP_003134117.1 PFAM: Metallo-beta-lactamase superfamily YP_003134118.1 PFAM: short chain dehydrogenase YP_003134119.1 PFAM: Nitroreductase family YP_003134120.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003134121.1 PFAM: GAF domain; Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003134122.1 PFAM: Universal stress protein family YP_003134123.1 PFAM: Universal stress protein family YP_003134124.1 PFAM: Universal stress protein family YP_003134125.1 PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_003134126.1 PFAM: Peptidase family M50 YP_003134127.1 PFAM: Universal stress protein family YP_003134129.1 PFAM: Hsp20/alpha crystallin family YP_003134131.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003134132.1 PFAM: tRNA synthetases class I (C) catalytic domain; TIGRFAM: cysteinyl-tRNA synthetase YP_003134133.1 PFAM: Receptor family ligand binding region YP_003134134.1 PFAM: Branched-chain amino acid transport system / permease component YP_003134135.1 PFAM: Branched-chain amino acid transport system / permease component YP_003134136.1 PFAM: ABC transporter YP_003134137.1 PFAM: ABC transporter YP_003134139.1 PFAM: Uncharacterised protein family (UPF0089) YP_003134140.1 PFAM: short chain dehydrogenase YP_003134141.1 PFAM: Radical SAM superfamily; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH YP_003134143.1 PFAM: Prenyltransferase and squalene oxidase repeat; TIGRFAM: squalene/oxidosqualene cyclases; squalene-hopene cyclase YP_003134144.1 PFAM: Polyprenyl synthetase YP_003134145.1 PFAM: Flavin containing amine oxidoreductase; TIGRFAM: squalene-associated FAD-dependent desaturase YP_003134146.1 PFAM: Squalene/phytoene synthase; TIGRFAM: squalene synthase HpnD YP_003134147.1 PFAM: Squalene/phytoene synthase; TIGRFAM: squalene synthase HpnC YP_003134148.1 PFAM: Universal stress protein family YP_003134149.1 PFAM: ROK family YP_003134150.1 PFAM: Domain of unknown function DUF81 YP_003134152.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134153.1 PFAM: ATP-grasp domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Carboxyl transferase domain; Biotin-requiring enzyme YP_003134154.1 PFAM: Major Facilitator Superfamily YP_003134155.1 PFAM: Domain of unknown function (DUF2382); PRC-barrel domain; TIGRFAM: conserved domain YP_003134156.1 PFAM: Uncharacterized protein family UPF0027 YP_003134159.1 PFAM: Histidine kinase; GAF domain YP_003134160.1 PFAM: PASTA domain YP_003134161.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: glycine betaine aldehyde dehydrogenase YP_003134162.1 PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport YP_003134164.1 PFAM: FAD dependent oxidoreductase YP_003134166.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_003134168.1 PFAM: Acyltransferase family YP_003134169.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_003134170.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134171.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_003134173.1 PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase YP_003134174.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003134175.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003134176.1 PFAM: Bacterial extracellular solute-binding protein YP_003134177.1 PFAM: Bacterial regulatory proteins, lacI family; Periplasmic binding proteins and sugar binding domain of the LacI family YP_003134178.1 PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain YP_003134179.1 PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family YP_003134180.1 PFAM: NIL domain; ABC transporter YP_003134181.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003134186.1 PFAM: Uncharacterised BCR, YbaB family COG0718 YP_003134188.1 PFAM: PIN domain YP_003134190.1 PFAM: Aminotransferase class I and II YP_003134191.1 PFAM: SIS domain; Helix-turn-helix domain, rpiR family YP_003134192.1 PFAM: Amino acid permease YP_003134193.1 PFAM: Predicted ATPase of the ABC class YP_003134194.1 PFAM: CoA-transferase family III YP_003134195.1 PFAM: Bacterial regulatory proteins, tetR family; Tetracyclin repressor, C-terminal all-alpha domain YP_003134196.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003134197.1 PFAM: alpha/beta hydrolase fold YP_003134199.1 PFAM: short chain dehydrogenase YP_003134200.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_003134201.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134204.1 PFAM: NAD dependent epimerase/dehydratase family YP_003134210.1 PFAM: FtsK/SpoIIIE family YP_003134215.1 PFAM: MerR family regulatory protein; TIGRFAM: DNA binding domain, excisionase family YP_003134216.1 PFAM: Phage integrase family YP_003134217.1 Catalyzes the conversion of citrate to isocitrate YP_003134218.1 PFAM: Beta-lactamase YP_003134219.1 PFAM: Prolyl oligopeptidase family; Dipeptidyl peptidase IV (DPP IV) N-terminal region YP_003134220.1 PFAM: Aminotransferase class-III; TIGRFAM: ornithine aminotransferase YP_003134221.1 PFAM: PAP2 superfamily YP_003134222.1 PFAM: AFG1-like ATPase YP_003134223.1 PFAM: RibD C-terminal domain YP_003134224.1 PFAM: alpha/beta hydrolase fold; TAP-like protein YP_003134225.1 PFAM: Endonuclease/Exonuclease/phosphatase family YP_003134226.1 PFAM: AMP-binding enzyme YP_003134227.1 PFAM: SNARE associated Golgi protein YP_003134228.1 PFAM: Protein kinase domain YP_003134230.1 PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase YP_003134231.1 PFAM: Chlorite dismutase YP_003134232.1 PFAM: Flavin containing amine oxidoreductase; TIGRFAM: protoporphyrinogen oxidase YP_003134233.1 PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: uroporphyrinogen decarboxylase YP_003134235.1 PFAM: 3'-5' exonuclease; HRDC domain; TIGRFAM: ribonuclease D YP_003134236.1 PFAM: HAMP domain; His Kinase A (phosphoacceptor) domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003134237.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_003134238.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_003134239.1 PFAM: FCD domain; Bacterial regulatory proteins, gntR family YP_003134240.1 PFAM: Shikimate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family YP_003134241.1 PFAM: GntP family permease; TIGRFAM: gluconate transporter YP_003134242.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134243.1 PFAM: MMPL family YP_003134244.1 PFAM: tRNA (Uracil-5-)-methyltransferase; TRAM domain; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA YP_003134248.1 PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) YP_003134252.1 PFAM: Inositol monophosphatase family YP_003134253.1 PFAM: ROK family YP_003134254.1 PFAM: Sigma-70 factor, region 1.2; Sigma-70 region 3; Sigma-70 region 2; Sigma-70, region 4; TIGRFAM: RNA polymerase sigma factor RpoD, C-terminal domain; RNA polymerase sigma factor, sigma-70 family YP_003134255.1 PFAM: Integral membrane protein DUF6 YP_003134257.1 PFAM: ROK family YP_003134258.1 PFAM: Branched-chain amino acid transport system / permease component YP_003134259.1 PFAM: ABC transporter YP_003134261.1 PFAM: Type III restriction enzyme, res subunit YP_003134262.1 PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN) YP_003134264.1 PFAM: Indigoidine synthase A like protein YP_003134265.1 PFAM: pfkB family carbohydrate kinase YP_003134267.1 PFAM: Methyltransferase small domain YP_003134268.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_003134269.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma factors in this cluster are active during stationary phase YP_003134270.1 PFAM: Fumarase C-terminus; Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region YP_003134273.1 PFAM: Polysaccharide deacetylase YP_003134276.1 PFAM: Luciferase-like monooxygenase YP_003134277.1 PFAM: Luciferase-like monooxygenase YP_003134278.1 PFAM: Methylmalonyl-CoA mutase; B12 binding domain; ArgK protein; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain YP_003134279.1 PFAM: Conserved hypothetical ATP binding protein YP_003134280.1 PFAM: Protein of unknown function (DUF742) YP_003134281.1 PFAM: Roadblock/LC7 domain YP_003134282.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; HAMP domain; Nitrate and nitrite sensing YP_003134283.1 PFAM: Pyridoxal-dependent decarboxylase, pyridoxal binding domain; Pyridoxal-dependent decarboxylase, C-terminal sheet domain YP_003134284.1 PFAM: S-adenosylmethionine decarboxylase; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme, Bacillus form YP_003134285.1 PFAM: Spermine/spermidine synthase YP_003134291.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003134292.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134293.1 NADP-dependent semialdehyde dehydrogenase; part of alternative pathway from alpha-ketoglutarate to succinate YP_003134294.1 PFAM: Domain of unknown function (DUF397) YP_003134295.1 PFAM: Helix-turn-helix YP_003134297.1 PFAM: Acyl-CoA thioesterase; TIGRFAM: acyl-CoA thioesterase II YP_003134298.1 PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase YP_003134299.1 PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter YP_003134300.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_003134301.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_003134303.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_003134304.1 PFAM: alpha/beta hydrolase fold YP_003134306.1 PFAM: NUDIX domain YP_003134307.1 PFAM: BadF/BadG/BcrA/BcrD ATPase family; ROK family; TIGRFAM: ROK family protein (putative glucokinase) YP_003134309.1 PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase (arsA) YP_003134310.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_003134311.1 PFAM: Calcineurin-like phosphoesterase YP_003134313.1 PFAM: AMP-binding enzyme YP_003134314.1 PFAM: ABC transporter; TIGRFAM: daunorubicin resistance ABC transporter ATP-binding subunit YP_003134315.1 PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family YP_003134316.1 PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain YP_003134318.1 PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW YP_003134319.1 PFAM: MraZ protein; TIGRFAM: mraZ protein YP_003134324.1 PFAM: ATPase family associated with various cellular activities (AAA) YP_003134325.1 PFAM: Protein of unknown function DUF58 YP_003134326.1 PFAM: Transglutaminase-like superfamily YP_003134328.1 PFAM: impB/mucB/samB family YP_003134329.1 PFAM: Methyltransferase domain; TIGRFAM: methyltransferase, FkbM family YP_003134330.1 PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_003134331.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_003134334.1 PFAM: PspA/IM30 family YP_003134335.1 PFAM: Helix-turn-helix YP_003134336.1 PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain YP_003134337.1 PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_003134338.1 PFAM: Uncharacterized protein family UPF0004; Radical SAM superfamily; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme YliG, TIGR01125 YP_003134339.1 catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis YP_003134340.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_003134341.1 PFAM: FtsK/SpoIIIE family; Ftsk gamma domain YP_003134343.1 PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_003134344.1 PFAM: Integral membrane protein DUF6 YP_003134345.1 PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein YP_003134346.1 PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase YP_003134347.1 PFAM: Protein kinase domain YP_003134349.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_003134350.1 PFAM: HicB family YP_003134352.1 PFAM: Protein of unknown function (DUF1006) YP_003134353.1 PFAM: Acetyltransferase (GNAT) family YP_003134354.1 PFAM: S4 domain; RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase family YP_003134355.1 PFAM: Putative transcriptional regulators (Ypuh-like); TIGRFAM: segregation and condensation protein B YP_003134356.1 PFAM: ScpA/B protein YP_003134358.1 PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_003134359.1 PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; TIGRFAM: tyrosine recombinase XerD YP_003134360.1 PFAM: Protein of unknown function (DUF1264) YP_003134361.1 PFAM: Domain of unknown function (DUF1707) YP_003134362.1 PFAM: NUDIX domain YP_003134363.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_003134364.1 PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase YP_003134366.1 PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN YP_003134367.1 PFAM: ATP-NAD kinase YP_003134368.1 PFAM: FtsJ-like methyltransferase; S4 domain; TIGRFAM: hemolysin TlyA family protein YP_003134370.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase Superfamily Class (subfamily) IIA YP_003134372.1 PFAM: S4 domain; tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase YP_003134373.1 PFAM: Methylpurine-DNA glycosylase (MPG); TIGRFAM: DNA-3-methyladenine glycosylase (3mg) YP_003134374.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_003134375.1 PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase YP_003134376.1 PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor YP_003134377.1 PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase YP_003134378.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_003134379.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_003134380.1 PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase YP_003134381.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_003134382.1 PFAM: Putative tRNA binding domain; Ferredoxin-fold anticodon binding domain; tRNA synthetase B5 domain; B3/4 domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial YP_003134383.1 PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit YP_003134384.1 PFAM: RNA 2'-O ribose methyltransferase substrate binding; SpoU rRNA Methylase family YP_003134385.1 PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20 YP_003134386.1 PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35 YP_003134387.1 PFAM: Translation initiation factor IF-3, N-terminal domain; Translation initiation factor IF-3, C-terminal domain; TIGRFAM: translation initiation factor IF-3 YP_003134389.1 PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP, putative YP_003134390.1 PFAM: Response regulator receiver domain YP_003134391.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box YP_003134392.1 PFAM: Sodium:dicarboxylate symporter family YP_003134393.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_003134394.1 PFAM: Acyltransferase family YP_003134396.1 PFAM: Metallo-beta-lactamase superfamily YP_003134397.1 PFAM: NUDIX domain YP_003134399.1 PFAM: RES domain YP_003134400.1 PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat YP_003134401.1 PFAM: Integral membrane protein TerC family YP_003134402.1 PFAM: X-Pro dipeptidyl-peptidase (S15 family); ABC transporter; X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain YP_003134405.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_003134406.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_003134408.1 PFAM: Bacterial regulatory protein, arsR family YP_003134409.1 PFAM: Protein of unknown function (DUF402) YP_003134410.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; in Mycobacterium tuberculosis the C-terminal UPF0157 domain appears to be necessary for proper folding of the N-terminal domain YP_003134411.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_003134412.1 PFAM: Methyltransferase domain YP_003134414.1 PFAM: 3'-5' exonuclease; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, C-terminal SAM fold; TIGRFAM: DNA polymerase I YP_003134415.1 PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1 YP_003134417.1 PFAM: ANTAR domain; Response regulator receiver domain YP_003134420.1 PFAM: Acetyltransferase (GNAT) family YP_003134421.1 PFAM: Major Facilitator Superfamily YP_003134422.1 PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain YP_003134423.1 PFAM: Rieske [2Fe-2S] domain YP_003134424.1 PFAM: Transcriptional regulator PadR-like family YP_003134425.1 PFAM: Acetyltransferase (GNAT) family YP_003134427.1 PFAM: Luciferase-like monooxygenase YP_003134428.1 PFAM: Flavin reductase like domain YP_003134429.1 PFAM: NADPH-dependent FMN reductase YP_003134430.1 PFAM: Aldehyde dehydrogenase family YP_003134431.1 PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family YP_003134433.1 PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_003134434.1 PFAM: Substrate binding domain of ABC-type glycine betaine transport system; TIGRFAM: choline ABC transporter, periplasmic binding protein YP_003134435.1 PFAM: ABC transporter; CBS domain pair; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit YP_003134436.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003134437.1 PFAM: Sulfatase YP_003134438.1 PFAM: Domain of unknown function (DUF323) YP_003134439.1 PFAM: Domain of unknown function DUF YP_003134440.1 PFAM: Domain of unknown function DUF YP_003134441.1 PFAM: AMP-binding enzyme YP_003134443.1 PFAM: FAD dependent oxidoreductase YP_003134445.1 PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_003134446.1 PFAM: Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain YP_003134449.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_003134450.1 PFAM: RibD C-terminal domain YP_003134456.1 PFAM: Flavin containing amine oxidoreductase; TIGRFAM: phytoene desaturase YP_003134457.1 PFAM: Squalene/phytoene synthase YP_003134458.1 TIGRFAM: lycopene cyclase domain YP_003134459.1 TIGRFAM: lycopene cyclase domain YP_003134460.1 PFAM: Methyltransferase domain YP_003134461.1 PFAM: Flavin containing amine oxidoreductase YP_003134462.1 PFAM: Rieske [2Fe-2S] domain YP_003134463.1 PFAM: ABC transporter YP_003134464.1 PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: phenylacetate-CoA oxygenase/reductase, PaaK subunit YP_003134465.1 PFAM: Domain of unknown function DUF59; TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit YP_003134466.1 PFAM: Phenylacetic acid catabolic protein; TIGRFAM: phenylacetate-CoA oxygenase, PaaI subunit YP_003134467.1 PFAM: Phenylacetic acid degradation B; TIGRFAM: phenylacetate-CoA oxygenase, PaaH subunit YP_003134468.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_003134469.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA YP_003134470.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_003134471.1 PFAM: Thioesterase superfamily; TIGRFAM: phenylacetic acid degradation protein PaaD; uncharacterized domain 1 YP_003134472.1 PFAM: AMP-binding enzyme; TIGRFAM: phenylacetate-CoA ligase YP_003134473.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134475.1 PFAM: Bacterial regulatory proteins, tetR family; Tetracyclin repressor, C-terminal all-alpha domain YP_003134476.1 PFAM: Acetyltransferase (GNAT) family YP_003134478.1 PFAM: Choline/Carnitine o-acyltransferase YP_003134479.1 PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_003134480.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_003134481.1 PFAM: MarR family YP_003134482.1 PFAM: Major Facilitator Superfamily YP_003134483.1 PFAM: AMP-binding enzyme; TIGRFAM: O-succinylbenzoate-CoA ligase YP_003134484.1 catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA YP_003134490.1 PFAM: FAD binding domain YP_003134491.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134492.1 PFAM: Domain of unknown function (DUF1994) YP_003134494.1 PFAM: ABC transporter YP_003134495.1 PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_003134496.1 PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003134499.1 PFAM: Cyclic nucleotide-binding domain YP_003134503.1 PFAM: Endonuclease I YP_003134504.1 PFAM: Glycosyl transferase family 2; Polysaccharide deacetylase; Acyltransferase family YP_003134507.1 PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_003134508.1 PFAM: Cytochrome P450 YP_003134509.1 Required for the synthesis of the thiazole moiety YP_003134511.1 PFAM: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form YP_003134512.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_003134513.1 PFAM: B12 binding domain; Pterin binding enzyme; Homocysteine S-methyltransferase; B12 binding domain; Vitamin B12 dependent methionine synthase, activation domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase YP_003134514.1 PFAM: pfkB family carbohydrate kinase YP_003134515.1 PFAM: S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; S-adenosylmethionine synthetase, C-terminal domain; TIGRFAM: S-adenosylmethionine synthetase YP_003134516.1 PFAM: Methyltransferase domain; Methyltransferase domain YP_003134518.1 PFAM: Helix-turn-helix YP_003134519.1 PFAM: Bacterial transcriptional regulator; IclR helix-turn-helix domain YP_003134520.1 PFAM: Bacterial regulatory proteins, gntR family YP_003134521.1 PFAM: Protein of unknown function (DUF1470) YP_003134522.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_003134523.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; Sigma-70 region 3; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily YP_003134524.1 PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain YP_003134525.1 PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain YP_003134526.1 PFAM: Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain YP_003134527.1 PFAM: short chain dehydrogenase YP_003134529.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: beta-phosphoglucomutase family hydrolase; haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_003134530.1 PFAM: Glycosyl hydrolase family 65 central catalytic domain; Glycosyl hydrolase family 65, C-terminal domain; Glycosyl hydrolase family 65, N-terminal domain YP_003134532.1 PFAM: Ppx/GppA phosphatase family YP_003134533.1 PFAM: Bacterial protein of unknown function (DUF885) YP_003134535.1 PFAM: S4 domain; RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family YP_003134536.1 PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase YP_003134537.1 PFAM: Uncharacterised ACR, YggU family COG1872 YP_003134538.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_003134540.1 PFAM: DivIVA protein YP_003134541.1 PFAM: YGGT family YP_003134542.1 PFAM: Protein of unknown function (DUF552) YP_003134543.1 PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family YP_003134544.1 PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726 YP_003134545.1 PFAM: Tubulin/FtsZ family, C-terminal domain; Tubulin/FtsZ family, GTPase domain; TIGRFAM: cell division protein FtsZ YP_003134546.1 PFAM: Protein of unknown function (DUF664) YP_003134547.1 PFAM: POTRA domain, FtsQ-type YP_003134548.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_003134549.1 PFAM: Glycosyltransferase family 28 C-terminal domain; Glycosyltransferase family 28 N-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_003134550.1 PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW YP_003134551.1 PFAM: Mur ligase middle domain; Mur ligase family, glutamate ligase domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_003134552.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_003134553.1 PFAM: Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_003134554.1 PFAM: Mur ligase middle domain; Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetases YP_003134556.1 PFAM: Acetyltransferase (GNAT) family; CoA binding domain YP_003134557.1 PFAM: Histone deacetylase domain YP_003134558.1 PFAM: Rhodanese-like domain YP_003134559.1 PFAM: FeoA domain; Iron dependent repressor, N-terminal DNA binding domain; Iron dependent repressor, metal binding and dimerisation domain YP_003134560.1 PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase YP_003134562.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue YP_003134563.1 PFAM: Prolyl oligopeptidase family; Prolyl oligopeptidase, N-terminal beta-propeller domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_003134564.1 PFAM: NAD dependent epimerase/dehydratase family YP_003134565.1 catalyzes the reduction of ribonucleotides to deoxyribonucleotides; the rate-limiting step in dNTP synthesis YP_003134566.1 PFAM: ATP cone domain; TIGRFAM: transcriptional regulator NrdR YP_003134567.1 PFAM: LexA DNA binding domain; Peptidase S24-like; TIGRFAM: SOS regulatory protein LexA YP_003134569.1 PFAM: GTPase of unknown function; TIGRFAM: GTP-binding proten HflX; small GTP-binding protein domain YP_003134570.1 PFAM: Bacterial regulatory protein, arsR family YP_003134571.1 PFAM: Major Facilitator Superfamily YP_003134572.1 PFAM: Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase YP_003134573.1 PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA) YP_003134575.1 PFAM: Domain of Unknown Function (DUF349) YP_003134577.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_003134578.1 PFAM: ABC transporter YP_003134579.1 PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_003134580.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_003134581.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_003134582.1 catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source YP_003134583.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_003134586.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_003134587.1 PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase YP_003134588.1 PFAM: Protein of unknown function (DUF1222) YP_003134589.1 PFAM: RecX family YP_003134590.1 PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA YP_003134592.1 PFAM: Hsp70 protein YP_003134593.1 PFAM: DEAD/DEAH box helicase; Helicase conserved C-terminal domain; DEAD/H associated YP_003134594.1 PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase YP_003134597.1 PFAM: Acetyltransferase (GNAT) family YP_003134598.1 PFAM: Integral membrane protein DUF6 YP_003134599.1 PFAM: Sodium/calcium exchanger protein YP_003134600.1 PFAM: Bacterial protein of unknown function (DUF885) YP_003134601.1 PFAM: Polyprenyl synthetase YP_003134603.1 PFAM: Bacterial regulatory proteins, luxR family YP_003134607.1 PFAM: PASTA domain; Protein kinase domain YP_003134608.1 PFAM: Uncharacterised protein family (UPF0089); TIGRFAM: acyltransferase, WS/DGAT/MGAT YP_003134609.1 PFAM: Class-II DAHP synthetase family; TIGRFAM: 3-deoxy-7-phosphoheptulonate synthase, class II YP_003134611.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit YP_003134612.1 PFAM: GXGXG motif; Glutamate synthase central domain; Conserved region in glutamate synthase; Glutamine amidotransferases class-II YP_003134613.1 PFAM: Periplasmic binding protein YP_003134614.1 PFAM: FecCD transport family YP_003134615.1 PFAM: ABC transporter YP_003134616.1 PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_003134617.1 PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit YP_003134618.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_003134619.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_003134620.1 PFAM: Tryptophan-associated transmembrane protein (Trp_oprn_chp); TIGRFAM: trp region conserved hypothetical membrane protein YP_003134621.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_003134622.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134623.1 PFAM: Phosphoribosyl-AMP cyclohydrolase YP_003134624.1 PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit YP_003134626.1 PFAM: Pyridoxamine 5'-phosphate oxidase YP_003134627.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide and the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)anthranilate; involved in histidine and tryptophan biosynthesis YP_003134628.1 PFAM: Glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_003134629.1 PFAM: Major Facilitator Superfamily YP_003134630.1 PFAM: VanW like protein YP_003134631.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase YP_003134632.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003134633.1 PFAM: Electron transfer flavoprotein FAD-binding domain; Electron transfer flavoprotein domain YP_003134634.1 PFAM: Electron transfer flavoprotein domain YP_003134635.1 PFAM: Uncharacterised protein, DegV family COG1307; TIGRFAM: degV family protein YP_003134636.1 PFAM: Methyltransferase domain YP_003134637.1 PFAM: Glycosyl hydrolase family 57; Domain of unknown function (DUF1957) YP_003134638.1 PFAM: Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, immunoglobulin-like beta-sandwich domain; Glycosyl hydrolases family 2, sugar binding domain YP_003134639.1 PFAM: Glycosyl transferases group 1 YP_003134641.1 PFAM: Protein of unknown function (DUF1348); TIGRFAM: conserved hypothetical protein YP_003134642.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134643.1 PFAM: Malate synthase; TIGRFAM: malate synthase A YP_003134644.1 PFAM: Isocitrate lyase family; TIGRFAM: isocitrate lyase YP_003134645.1 PFAM: Domain of unknown function (DUF955); Predicted transcriptional regulator (DUF2083); Helix-turn-helix YP_003134646.1 PFAM: Zinc carboxypeptidase YP_003134647.1 PFAM: Bacterial transferase hexapeptide (three repeats) YP_003134648.1 PFAM: Inosine-uridine preferring nucleoside hydrolase YP_003134649.1 PFAM: NlpC/P60 family YP_003134650.1 PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_003134653.1 PFAM: Methyltransferase domain YP_003134654.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003134655.1 PFAM: ABC transporter YP_003134656.1 PFAM: Carbohydrate phosphorylase; TIGRFAM: alpha-glucan phosphorylases YP_003134658.1 PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_003134659.1 PFAM: Domain of unknown function DUF77; TIGRFAM: conserved hypothetical protein TIGR00106 YP_003134660.1 PFAM: MarR family YP_003134662.1 TIGRFAM: mannose-6-phosphate isomerase, class I YP_003134663.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_003134664.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase YP_003134666.1 PFAM: Universal stress protein family YP_003134667.1 PFAM: Adenylate and Guanylate cyclase catalytic domain YP_003134668.1 PFAM: DbpA RNA binding domain; Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_003134669.1 TIGRFAM: gamma-glutamyl phosphate reductase YP_003134672.1 PFAM: Methyltransferase domain YP_003134673.1 PFAM: Exonuclease YP_003134674.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_003134675.1 PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family; ribose 5-phosphate isomerase YP_003134676.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone YP_003134677.1 PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_003134678.1 PFAM: Xylose isomerase-like TIM barrel YP_003134679.1 PFAM: short chain dehydrogenase YP_003134680.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain YP_003134681.1 PFAM: GntP family permease; TIGRFAM: gluconate transporter YP_003134682.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain YP_003134683.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain YP_003134684.1 PFAM: Ykud domain YP_003134685.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_003134686.1 PFAM: 2-nitropropane dioxygenase YP_003134688.1 PFAM: Pentapeptide repeats (8 copies) YP_003134689.1 PFAM: PspC domain YP_003134690.1 PFAM: Methyltransferase domain YP_003134692.1 PFAM: AMP-binding enzyme YP_003134693.1 PFAM: Major Facilitator Superfamily YP_003134694.1 PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_003134696.1 PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_003134697.1 PFAM: Helix-turn-helix YP_003134699.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134703.1 PFAM: Helix-turn-helix YP_003134708.1 PFAM: Glycosyl hydrolases family 25 YP_003134710.1 PFAM: 'Cold-shock' DNA-binding domain YP_003134711.1 PFAM: Receptor family ligand binding region YP_003134714.1 PFAM: AhpC/TSA family YP_003134715.1 PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family YP_003134716.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_003134717.1 PFAM: Methyltransferase domain YP_003134718.1 PFAM: Metallo-beta-lactamase superfamily YP_003134719.1 PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase YP_003134720.1 PFAM: Rhomboid family YP_003134721.1 PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthases YP_003134722.1 PFAM: ThiS family YP_003134723.1 PFAM: Mov34/MPN/PAD-1 family YP_003134725.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS YP_003134726.1 PFAM: Peptidase family S58 YP_003134727.1 PFAM: Domain of unknown function (DUF2017) YP_003134728.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS YP_003134729.1 PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: putative nicotinate phosphoribosyltransferase YP_003134730.1 PFAM: Isochorismatase family YP_003134731.1 PFAM: pfkB family carbohydrate kinase YP_003134734.1 PFAM: Peptidyl-tRNA hydrolase PTH2 YP_003134735.1 PFAM: ACT domain; haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; phosphoserine phosphatase SerB YP_003134736.1 PFAM: Cytochrome C and Quinol oxidase polypeptide I; TIGRFAM: cytochrome c oxidase, subunit I YP_003134737.1 PFAM: alpha/beta hydrolase fold YP_003134739.1 PFAM: Type I phosphodiesterase / nucleotide pyrophosphatase YP_003134740.1 PFAM: Putative regulatory protein (CxxC_CxxC_SSSS); TIGRFAM: putative regulatory protein, FmdB family YP_003134741.1 PFAM: PTS HPr component phosphorylation site; PTS system fructose IIA component; TIGRFAM: Phosphotransferase System HPr (HPr) Family; dihydroxyacetone kinase, phosphotransfer subunit YP_003134742.1 PFAM: DAK2 domain; TIGRFAM: dihydroxyacetone kinase, phosphoprotein-dependent, L subunit YP_003134743.1 PFAM: Dak1 domain; TIGRFAM: dihydroxyacetone kinase, DhaK subunit YP_003134745.1 PFAM: Protein of unknown function DUF91 YP_003134746.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_003134747.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; ectoine/hydroxyectoine ABC transporter, permease protein EhuD YP_003134748.1 PFAM: Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: ectoine/hydroxyectoine ABC transporter solute-binding protein; Tat (twin-arginine translocation) pathway signal sequence YP_003134749.1 PFAM: NUDIX domain YP_003134750.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003134751.1 PFAM: ABC transporter; TIGRFAM: ectoine/hydroxyectoine ABC transporter, ATP-binding protein YP_003134752.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: ectoine/hydroxyectoine ABC transporter, permease protein EhuD; amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_003134753.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; ectoine/hydroxyectoine ABC transporter, permease protein EhuC YP_003134754.1 PFAM: Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: ectoine/hydroxyectoine ABC transporter solute-binding protein YP_003134755.1 PFAM: LysE type translocator YP_003134756.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_003134757.1 PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase YP_003134758.1 PFAM: Protein of unknown function (DUF2550) YP_003134759.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_003134760.1 PFAM: ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; ATP synthase alpha/beta family, beta-barrel domain; TIGRFAM: ATP synthase, F1 beta subunit YP_003134761.1 PFAM: ATP synthase; TIGRFAM: ATP synthase, F1 gamma subunit YP_003134762.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_003134763.1 PFAM: ATP synthase delta (OSCP) subunit; TIGRFAM: ATP synthase, F1 delta subunit YP_003134764.1 PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase, F0 subunit b YP_003134765.1 PFAM: ATP synthase subunit C YP_003134766.1 PFAM: ATP synthase A chain; TIGRFAM: ATP synthase subunit 6 (eukaryotes), also subunit A (prokaryotes) YP_003134768.1 PFAM: Glycosyl transferase family 4 YP_003134769.1 PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_003134770.1 PFAM: Methyltransferase small domain; TIGRFAM: protein-(glutamine-N5) methyltransferase, release factor-specific; HemK family putative methylases YP_003134771.1 PFAM: ABC-2 type transporter YP_003134772.1 PFAM: ABC-2 type transporter YP_003134773.1 PFAM: ABC transporter YP_003134776.1 PFAM: alpha/beta hydrolase fold YP_003134777.1 PFAM: SnoaL-like polyketide cyclase YP_003134779.1 PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase YP_003134780.1 PFAM: alpha/beta hydrolase fold YP_003134781.1 PFAM: FAD dependent oxidoreductase; FAD binding domain YP_003134782.1 PFAM: Nitroreductase family YP_003134783.1 PFAM: Beta-ketoacyl synthase, C-terminal domain; Beta-ketoacyl synthase, N-terminal domain YP_003134784.1 PFAM: Aminomethyltransferase folate-binding domain YP_003134785.1 PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ YP_003134786.1 TIGRFAM: acyl carrier protein YP_003134787.1 PFAM: short chain dehydrogenase YP_003134788.1 PFAM: FAD binding domain YP_003134789.1 PFAM: Transcriptional regulatory protein, C terminal; Bacterial transcriptional activator domain YP_003134790.1 PFAM: Glycosyltransferase family 28 C-terminal domain; TIGRFAM: glycosyltransferase, MGT family YP_003134791.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family YP_003134792.1 PFAM: NDP-hexose 2,3-dehydratase YP_003134793.1 PFAM: NAD dependent epimerase/dehydratase family YP_003134794.1 PFAM: Methyltransferase domain; C-methyltransferase; Hypothetical methyltransferase YP_003134795.1 PFAM: Bacterial regulatory proteins, luxR family YP_003134796.1 PFAM: RF-1 domain; PCRF domain; TIGRFAM: peptide chain release factor 1 YP_003134797.1 PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31 YP_003134798.1 PFAM: Rho termination factor, N-terminal domain; Rho termination factor, RNA-binding domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: transcription termination factor Rho YP_003134799.1 PFAM: GHMP kinases N terminal domain; GHMP kinases C terminal; TIGRFAM: homoserine kinase YP_003134800.1 PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase YP_003134801.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_003134802.1 PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase YP_003134803.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_003134805.1 PFAM: Domain of unknown function (DUF305) YP_003134806.1 PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_003134807.1 PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_003134808.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134809.1 PFAM: Putative peptidoglycan binding domain; Peptidase M15 YP_003134810.1 PFAM: Luciferase-like monooxygenase; Hemerythrin HHE cation binding domain YP_003134811.1 PFAM: Transglycosylase SLT domain YP_003134812.1 PFAM: CoA binding domain YP_003134813.1 PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, central domain YP_003134814.1 PFAM: Glutathione S-transferase, C-terminal domain YP_003134815.1 PFAM: Amidase YP_003134816.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_003134817.1 PFAM: Asp/Glu/Hydantoin racemase YP_003134818.1 PFAM: FCD domain; Bacterial regulatory proteins, gntR family YP_003134819.1 PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: tartrate dehydrogenase YP_003134820.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase YP_003134821.1 PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type YP_003134824.1 PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD YP_003134825.1 thiamine-pyrophosphate requiring enzyme YP_003134826.1 PFAM: 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YP_003134827.1 PFAM: Thiolase, N-terminal domain; Thiolase, C-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases YP_003134828.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134829.1 PFAM: Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, C-terminal domain YP_003134830.1 PFAM: Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, C-terminal domain YP_003134833.1 PFAM: Inositol monophosphatase family YP_003134834.1 PFAM: Flavoprotein YP_003134835.1 PFAM: Helix-turn-helix YP_003134836.1 PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains YP_003134837.1 PFAM: Domain related to MnhB subunit of Na+/H+ antiporter YP_003134838.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_003134839.1 PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains YP_003134841.1 PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF) YP_003134842.1 PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit YP_003134843.1 PFAM: haloacid dehalogenase-like hydrolase YP_003134844.1 PFAM: Protein of unknown function (DUF1130) YP_003134846.1 PFAM: Zinc-binding dehydrogenase; Alcohol dehydrogenase GroES-like domain YP_003134848.1 PFAM: Sodium:solute symporter family YP_003134849.1 PFAM: Luciferase-like monooxygenase YP_003134850.1 PFAM: NADPH-dependent FMN reductase YP_003134851.1 PFAM: Acetyltransferase (GNAT) family YP_003134852.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003134853.1 PFAM: ATP-grasp domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme; Biotin carboxylase C-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase YP_003134854.1 PFAM: Carboxyl transferase domain YP_003134856.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134857.1 PFAM: ABC transporter YP_003134859.1 PFAM: ABC transporter; ABC transporter transmembrane region YP_003134860.1 kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth YP_003134861.1 PFAM: Flavin-binding monooxygenase-like YP_003134862.1 PFAM: Proprotein convertase P-domain; Subtilase family; Peptidase inhibitor I9 YP_003134863.1 PFAM: Protein of unknown function DUF43 YP_003134865.1 PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain YP_003134866.1 PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase YP_003134868.1 PFAM: Phosphoglycerate mutase family YP_003134869.1 PFAM: Acetyltransferase (GNAT) family YP_003134871.1 PFAM: Diacylglycerol kinase catalytic domain YP_003134872.1 PFAM: Transcription factor WhiB YP_003134873.1 PFAM: Histidine kinase; PAS fold; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003134874.1 PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein YP_003134875.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma-70 factor, TIGR02947 family; RNA polymerase sigma factor, sigma-70 family YP_003134876.1 TIGRFAM: anti-sigma factor, TIGR02949 family YP_003134878.1 PFAM: Uncharacterised ACR, COG2135 YP_003134879.1 PFAM: Protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A; GTP-binding conserved hypothetical protein YP_003134881.1 PFAM: Protein of unknown function (DUF1396) YP_003134882.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 1 YP_003134884.1 PFAM: Uncharacterised protein family (UPF0089); TIGRFAM: acyltransferase, WS/DGAT/MGAT YP_003134885.1 PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding YP_003134889.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_003134891.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_003134892.1 PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein YP_003134894.1 PFAM: Sporulation and spore germination; Lipoprotein LpqB beta-propeller domain YP_003134895.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; HAMP domain; His Kinase A (phosphoacceptor) domain YP_003134896.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_003134897.1 PFAM: Bacterial transcriptional regulator; IclR helix-turn-helix domain YP_003134898.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_003134900.1 TIGRFAM: LPXTG-motif cell wall anchor domain YP_003134901.1 PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I YP_003134903.1 PFAM: Trm112p-like protein YP_003134904.1 converts mannose-6-phosphate to mannose-1-phosphate; the resulting product is then converted to GDP-mannose by ManC which is then used in the synthesis of mannose-containing glycoconjugates that are important for mediating entry into host cells YP_003134909.1 PFAM: Transcription factor WhiB YP_003134910.1 PFAM: Peptidase family M50 YP_003134912.1 PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- glucopyranoside deacetylase YP_003134913.1 PFAM: Oligopeptide/dipeptide transporter, C-terminal region; ABC transporter; TIGRFAM: phosphonate C-P lyase system protein PhnK YP_003134914.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003134915.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003134916.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_003134917.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_003134918.1 PFAM: Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor Tu domain 2; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain YP_003134919.1 PFAM: YCII-related domain YP_003134920.1 PFAM: NUDIX domain; TIGRFAM: mutator mutT protein YP_003134921.1 PFAM: ABC transporter YP_003134922.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003134923.1 PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: ABC transporter periplasmic binding protein, thiB subfamily YP_003134924.1 PFAM: Pterin 4 alpha carbinolamine dehydratase YP_003134927.1 PFAM: Phosphotransferase enzyme family YP_003134929.1 PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_003134930.1 PFAM: HAMP domain; His Kinase A (phosphoacceptor) domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003134932.1 PFAM: Acetyltransferase (GNAT) family YP_003134933.1 PFAM: Methyltransferase domain YP_003134934.1 PFAM: Acetyltransferase (GNAT) family YP_003134936.1 PFAM: CAAX amino terminal protease family YP_003134937.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134939.1 PFAM: CutA1 divalent ion tolerance protein YP_003134940.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_003134942.1 PFAM: AlkA N-terminal domain; Bacterial regulatory helix-turn-helix proteins, AraC family; Metal binding domain of Ada YP_003134943.1 PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_003134944.1 TIGRFAM: exonuclease SbcC YP_003134945.1 PFAM: Calcineurin-like phosphoesterase; TIGRFAM: exonuclease SbcD YP_003134946.1 PFAM: RmuC family YP_003134948.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_003134950.1 PFAM: Exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII, large subunit YP_003134951.1 PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit YP_003134952.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_003134953.1 PFAM: FAD binding domain; Pyridine nucleotide-disulphide oxidoreductase YP_003134954.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_003134955.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134956.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_003134957.1 PFAM: PhoH-like protein YP_003134958.1 PFAM: Putative undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_003134959.1 PFAM: Haemolysin-III related; TIGRFAM: channel protein, hemolysin III family YP_003134968.1 PFAM: BCCT family transporter; TIGRFAM: choline/carnitine/betaine transport YP_003134969.1 PFAM: GMC oxidoreductase; GMC oxidoreductase; TIGRFAM: choline dehydrogenase YP_003134970.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: glycine betaine aldehyde dehydrogenase YP_003134971.1 PFAM: Bacterial regulatory proteins, tetR family YP_003134973.1 PFAM: Esterase PHB depolymerase; TIGRFAM: esterase, PHB depolymerase family YP_003134974.1 PFAM: Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA oxidase; Acyl-CoA dehydrogenase, C-terminal domain YP_003134975.1 PFAM: Protein of unknown function, DUF255 YP_003134979.1 PFAM: GlcNAc-PI de-N-acetylase; TIGRFAM: mycothiol conjugate amidase Mca YP_003134981.1 PFAM: Prokaryotic transcription elongation factor, GreA/GreB, N-terminal domain; Prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain; TIGRFAM: transcription elongation factor GreA YP_003134982.1 PFAM: AsnC family YP_003134983.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase YP_003134984.1 catalyzes the formation of 2-oxobutanoate from L-threonine YP_003134986.1 PFAM: Cys/Met metabolism PLP-dependent enzyme YP_003134989.1 PFAM: Pyridoxal-phosphate dependent enzyme; CBS domain pair; TIGRFAM: cystathionine beta-synthase YP_003134990.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_003134992.1 PFAM: Protein of unknown function (DUF1112) YP_003134994.1 PFAM: Sortase family YP_003134996.1 PFAM: Periplasmic binding protein; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003134998.1 PFAM: GAF domain; Stage II sporulation protein E (SpoIIE) YP_003134999.1 PFAM: Stage II sporulation protein E (SpoIIE) YP_003135000.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003135001.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_003135002.1 PFAM: STAS domain YP_003135003.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_003135004.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003135005.1 PFAM: Major Facilitator Superfamily; TIGRFAM: polyol permease family YP_003135006.1 PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_003135007.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E YP_003135008.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone YP_003135009.1 PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family; ribose 5-phosphate isomerase YP_003135010.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YP_003135011.1 PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_003135012.1 PFAM: Class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase YP_003135013.1 PFAM: Protein of unknown function (DUF1211) YP_003135014.1 PFAM: short chain dehydrogenase; TIGRFAM: acetoin reductases YP_003135015.1 PFAM: Sugar (and other) transporter YP_003135016.1 PFAM: Tetratricopeptide repeat YP_003135017.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_003135018.1 PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4 YP_003135019.1 PFAM: Serine carboxypeptidase YP_003135020.1 PFAM: Ppx/GppA phosphatase family YP_003135022.1 PFAM: Protein of unknown function (DUF501) YP_003135023.1 PFAM: Septum formation initiator; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003135024.1 PFAM: Enolase, C-terminal TIM barrel domain; Enolase, N-terminal domain; TIGRFAM: phosphopyruvate hydratase YP_003135025.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_003135027.1 PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein YP_003135029.1 PFAM: DEAD/DEAH box helicase; CarD-like/TRCF domain; Helicase conserved C-terminal domain; TRCF domain; TIGRFAM: transcription-repair coupling factor (mfd) YP_003135030.1 PFAM: Glucose / Sorbosone dehydrogenase YP_003135031.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135032.1 PFAM: Fatty acid desaturase YP_003135033.1 PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_003135034.1 PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_003135035.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_003135036.1 PFAM: Ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form YP_003135037.1 PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase YP_003135038.1 PFAM: DivIVA protein YP_003135040.1 activates fatty acids by binding to coenzyme A YP_003135041.1 PFAM: ABC transporter YP_003135042.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis YP_003135043.1 PFAM: ABC transporter; NIL domain YP_003135044.1 PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase YP_003135045.1 PFAM: Transglycosylase-like domain; G5 domain; Domain of unknown function (DUF348) YP_003135046.1 PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family YP_003135047.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_003135049.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine YP_003135050.1 PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: conserved hypothetical protein TIGR00096 YP_003135051.1 PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase YP_003135052.1 PFAM: Protein kinase domain YP_003135053.1 PFAM: AMP-binding enzyme YP_003135054.1 PFAM: Glycosyl hydrolase family 20, catalytic domain YP_003135055.1 PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase YP_003135056.1 PFAM: Protein kinase domain YP_003135057.1 PFAM: Protein kinase domain YP_003135058.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_003135060.1 PFAM: Patatin-like phospholipase YP_003135062.1 PFAM: Acetyltransferase (GNAT) family YP_003135063.1 PFAM: MoeA C-terminal region (domain IV); MoeA N-terminal region (domain I and II); Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain YP_003135064.1 PFAM: Nucleotidyl transferase YP_003135065.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase YP_003135066.1 PFAM: Putative regulatory protein (CxxC_CxxC_SSSS); TIGRFAM: putative regulatory protein, FmdB family YP_003135067.1 PFAM: SAF domain; TIGRFAM: Flp pilus assembly protein CpaB YP_003135069.1 PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain YP_003135070.1 PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF) YP_003135071.1 PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 1 YP_003135072.1 PFAM: DeoR-like helix-turn-helix domain; Bacterial regulatory proteins, deoR family YP_003135073.1 PFAM: HAMP domain; His Kinase A (phosphoacceptor) domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003135074.1 PFAM: Transcriptional regulatory protein, C terminal; Response regulator receiver domain YP_003135075.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003135081.1 PFAM: RHS Repeat; TIGRFAM: YD repeat (two copies) YP_003135083.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_003135085.1 PFAM: Acetyltransferase (GNAT) family YP_003135086.1 PFAM: RibD C-terminal domain YP_003135087.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135088.1 PFAM: PE-PPE domain YP_003135090.1 PFAM: Bacterial regulatory proteins, luxR family; Sugar-specific transcriptional regulator TrmB YP_003135091.1 PFAM: UDP-glucoronosyl and UDP-glucosyl transferase; TIGRFAM: glycosyltransferase, MGT family YP_003135092.1 PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain YP_003135093.1 PFAM: GAF domain; Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box YP_003135094.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003135095.1 PFAM: Sugar (and other) transporter YP_003135096.1 PFAM: Aminomethyltransferase folate-binding domain YP_003135099.1 PFAM: RHS Repeat; TIGRFAM: intein N-terminal splicing region; YD repeat (two copies) YP_003135100.1 PFAM: Protein of unknown function (DUF574) YP_003135101.1 PFAM: Peptidase family M23 YP_003135102.1 PFAM: CBS domain pair; MgtE intracellular N domain; Divalent cation transporter; TIGRFAM: Mg2+ transporter (mgtE) YP_003135103.1 PFAM: Peptidase family M48 YP_003135104.1 PFAM: RQC domain; HRDC domain; Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ YP_003135106.1 PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain YP_003135107.1 PFAM: Acetyltransferase (GNAT) family YP_003135108.1 PFAM: Enoyl-CoA hydratase/isomerase family YP_003135109.1 PFAM: AMP-binding enzyme YP_003135110.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135112.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003135113.1 PFAM: 4'-phosphopantetheinyl transferase superfamily YP_003135114.1 PFAM: chorismate binding enzyme; TIGRFAM: isochorismate synthases YP_003135116.1 activates fatty acids by binding to coenzyme A YP_003135118.1 PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain YP_003135119.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135120.1 PFAM: FAD dependent oxidoreductase YP_003135121.1 PFAM: Metallo-beta-lactamase superfamily; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003135122.1 PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase YP_003135123.1 PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_003135124.1 PFAM: Penicillin-binding Protein dimerisation domain; NTF2-like N-terminal transpeptidase domain; Penicillin binding protein transpeptidase domain YP_003135127.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_003135128.1 PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, central domain YP_003135129.1 PFAM: Asparagine synthase YP_003135130.1 PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain YP_003135131.1 PFAM: Arginase family; TIGRFAM: agmatinase YP_003135132.1 PFAM: Taurine catabolism dioxygenase TauD, TfdA family YP_003135133.1 PFAM: Protein of unknown function, DUF482 YP_003135134.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_003135135.1 PFAM: Acetyltransferase (GNAT) family YP_003135136.1 PFAM: Integral membrane protein DUF6 YP_003135138.1 PFAM: Protein of unknown function (DUF1271) YP_003135139.1 PFAM: Cytochrome P450 YP_003135140.1 PFAM: short chain dehydrogenase YP_003135142.1 PFAM: Acetyltransferase (GNAT) family YP_003135143.1 PFAM: Bacterial regulatory proteins, gntR family; UTRA domain YP_003135145.1 PFAM: Conserved hypothetical ATP binding protein YP_003135146.1 PFAM: Protein of unknown function (DUF742) YP_003135147.1 PFAM: Roadblock/LC7 domain YP_003135148.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003135149.1 PFAM: Endonuclease V YP_003135150.1 PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, central domain YP_003135151.1 PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type) YP_003135152.1 PFAM: pfkB family carbohydrate kinase YP_003135153.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135154.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003135155.1 PFAM: Amidohydrolase family YP_003135156.1 PFAM: Aldose 1-epimerase YP_003135157.1 PFAM: SchA / CurD like protein YP_003135158.1 PFAM: Polyketide synthesis cyclase YP_003135159.1 PFAM: Protein of unknown function (DUF861) YP_003135160.1 PFAM: Beta-ketoacyl synthase, C-terminal domain; Beta-ketoacyl synthase, N-terminal domain YP_003135161.1 PFAM: Beta-ketoacyl synthase, C-terminal domain; Beta-ketoacyl synthase, N-terminal domain YP_003135162.1 PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein YP_003135163.1 PFAM: Polyketide cyclase / dehydrase and lipid transport YP_003135164.1 PFAM: Antibiotic biosynthesis monooxygenase YP_003135165.1 PFAM: Antibiotic biosynthesis monooxygenase YP_003135166.1 PFAM: Carboxyl transferase domain; Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit; acetyl-CoA carboxylase, carboxyl transferase, alpha subunit YP_003135167.1 PFAM: Biotin-requiring enzyme; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_003135168.1 PFAM: RimK-like ATP-grasp domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin carboxylase C-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase YP_003135169.1 PFAM: NB-ARC domain; Bacterial transcriptional activator domain; Transcriptional regulatory protein, C terminal YP_003135171.1 PFAM: Major Facilitator Superfamily YP_003135172.1 PFAM: Pyridoxamine 5'-phosphate oxidase; Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; TIGRFAM: pyridoxamine-phosphate oxidase YP_003135173.1 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle YP_003135174.1 PFAM: short chain dehydrogenase; alpha/beta hydrolase fold YP_003135175.1 PFAM: L-lactate permease; TIGRFAM: L-lactate transport YP_003135176.1 PFAM: Beta-lactamase YP_003135177.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate YP_003135179.1 PFAM: NAD dependent epimerase/dehydratase family YP_003135180.1 PFAM: Glycosyl transferase family 2 YP_003135181.1 PFAM: NAD dependent epimerase/dehydratase family YP_003135183.1 PFAM: SpoU rRNA Methylase family YP_003135185.1 PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain YP_003135186.1 PFAM: Major Facilitator Superfamily YP_003135187.1 PFAM: MarR family YP_003135188.1 PFAM: Permease family YP_003135189.1 PFAM: Protein of unknown function (DUF2530) YP_003135192.1 PFAM: Glutamine cyclotransferase YP_003135193.1 PFAM: Major Facilitator Superfamily YP_003135195.1 PFAM: 'Cold-shock' DNA-binding domain YP_003135197.1 PFAM: haloacid dehalogenase-like hydrolase YP_003135198.1 Catalyzes the rate-limiting step in dNTP synthesis YP_003135199.1 PFAM: AMP-binding enzyme YP_003135200.1 PFAM: Domain of unknown function (DUF307) YP_003135201.1 PFAM: Calcineurin-like phosphoesterase YP_003135202.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase Superfamily Class (subfamily) IIA; HAD-superfamily subfamily IIA hydrolase, TIGR01457 YP_003135203.1 PFAM: ABC transporter; TOBE domain YP_003135204.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: NifC-like ABC-type porter; molybdate ABC transporter, permease protein YP_003135205.1 PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein YP_003135206.1 PFAM: TOBE domain; MerR family regulatory protein; TIGRFAM: molybdenum-pterin binding domain; DNA binding domain, excisionase family YP_003135207.1 PFAM: Radical SAM superfamily; Molybdenum Cofactor Synthesis C; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial YP_003135208.1 PFAM: ThiS family YP_003135209.1 PFAM: Transglycosylase-like domain; LysM domain YP_003135210.1 PFAM: MoaE protein; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain YP_003135211.1 PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC YP_003135212.1 PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain YP_003135215.1 PFAM: Protein of unknown function (DUF742) YP_003135216.1 PFAM: Roadblock/LC7 domain YP_003135217.1 PFAM: Miro-like protein YP_003135218.1 PFAM: Protein of unknown function (DUF742) YP_003135219.1 PFAM: Roadblock/LC7 domain YP_003135220.1 PFAM: Nitrate and nitrite sensing; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; HAMP domain YP_003135221.1 PFAM: NMT1/THI5 like YP_003135222.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003135223.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003135224.1 PFAM: ABC transporter YP_003135225.1 PFAM: Nitrate and nitrite sensing; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; HAMP domain YP_003135227.1 PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit YP_003135228.1 PFAM: Protein of unknown function DUF72 YP_003135229.1 PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease, PfpI family YP_003135230.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_003135231.1 PFAM: Periplasmic binding protein YP_003135232.1 PFAM: FecCD transport family YP_003135233.1 PFAM: FecCD transport family YP_003135234.1 PFAM: ABC transporter YP_003135235.1 PFAM: Protein kinase domain YP_003135236.1 PFAM: 'Cold-shock' DNA-binding domain YP_003135237.1 PFAM: Protein of unknown function DUF124 YP_003135238.1 PFAM: Protein of unknown function DUF124; TIGRFAM: conserved hypothetical protein TIGR00266 YP_003135239.1 PFAM: MoeA C-terminal region (domain IV); Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); TIGRFAM: molybdenum cofactor synthesis domain YP_003135240.1 PFAM: Transglycosylase associated protein YP_003135241.1 PFAM: Phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor-related protein YP_003135242.1 PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase YP_003135243.1 PFAM: ATPase family associated with various cellular activities (AAA); ATPase family associated with various cellular activities (AAA) YP_003135246.1 PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase YP_003135247.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_003135248.1 PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase YP_003135249.1 PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase YP_003135250.1 PFAM: Tetratricopeptide repeat; Tetratricopeptide repeat; NB-ARC domain YP_003135251.1 PFAM: Nodulation protein A (NodA) YP_003135252.1 PFAM: MarR family YP_003135253.1 PFAM: Thiazole biosynthesis protein ThiG YP_003135254.1 PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS YP_003135255.1 PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO YP_003135256.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_003135258.1 PFAM: UTRA domain; Bacterial regulatory proteins, gntR family YP_003135259.1 PFAM: SIS domain YP_003135260.1 PFAM: BadF/BadG/BcrA/BcrD ATPase family YP_003135262.1 PFAM: GDSL-like Lipase/Acylhydrolase YP_003135263.1 PFAM: OmpA family YP_003135267.1 PFAM: Phytanoyl-CoA dioxygenase (PhyH); TIGRFAM: ectoine hydroxylase YP_003135268.1 N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid YP_003135269.1 catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde YP_003135270.1 PFAM: Acetyltransferase (GNAT) family; TIGRFAM: L-2,4-diaminobutyric acid acetyltransferase YP_003135272.1 PFAM: ROK family; MarR family YP_003135276.1 PFAM: Phospholipase/Carboxylesterase YP_003135277.1 PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_003135278.1 PFAM: MarR family YP_003135280.1 PFAM: Predicted membrane-bound metal-dependent hydrolase (DUF457) YP_003135281.1 PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain; DNA polymerase LigD, ligase domain YP_003135282.1 PFAM: Eukaryotic and archaeal DNA primase small subunit; TIGRFAM: DNA polymerase LigD, polymerase domain; DNA ligase D YP_003135283.1 PFAM: GAF domain; Stage II sporulation protein E (SpoIIE); Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003135284.1 PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor YP_003135285.1 PFAM: SIS domain YP_003135286.1 PFAM: Amidohydrolase family YP_003135288.1 PFAM: Rhodanese-like domain; Metallo-beta-lactamase superfamily YP_003135290.1 PFAM: B12 binding domain YP_003135291.1 PFAM: GAF domain; Stage II sporulation protein E (SpoIIE) YP_003135292.1 PFAM: Protein of unknown function (DUF1212) YP_003135293.1 PFAM: Glycosyltransferase family 20; TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming] YP_003135294.1 PFAM: Glycosyl hydrolases family 15; Trehalose-phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; trehalose-phosphatase YP_003135295.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_003135296.1 PFAM: Protein of unknown function (DUF461) YP_003135297.1 PFAM: CarD-like/TRCF domain YP_003135298.1 PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_003135299.1 PFAM: YgbB family; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_003135300.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase; haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_003135301.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_003135302.1 PFAM: RNA 2'-O ribose methyltransferase substrate binding; SpoU rRNA Methylase family; TIGRFAM: rRNA methylase, putative, group 3 YP_003135303.1 PFAM: MBOAT family YP_003135304.1 PFAM: UvrD/REP helicase YP_003135305.1 PFAM: DEAD/DEAH box helicase; Helicase conserved C-terminal domain; Domain of unknown function (DUF1998) YP_003135307.1 PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit YP_003135308.1 PFAM: Protein kinase domain YP_003135310.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_003135313.1 PFAM: ABC 3 transport family YP_003135314.1 PFAM: ABC transporter YP_003135315.1 PFAM: Periplasmic solute binding protein family YP_003135316.1 PFAM: Periplasmic binding proteins and sugar binding domain of the LacI family YP_003135317.1 PFAM: Carbonic anhydrase YP_003135318.1 PFAM: Helix-hairpin-helix motif; Iron-sulfur binding domain of endonuclease III; TIGRFAM: A/G-specific adenine glycosylase YP_003135319.1 PFAM: N-acetylmuramoyl-L-alanine amidase; Putative peptidoglycan binding domain YP_003135321.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135322.1 PFAM: alpha/beta hydrolase fold YP_003135323.1 PFAM: Peptidase family M1 YP_003135324.1 PFAM: Antibiotic biosynthesis monooxygenase YP_003135325.1 PFAM: Sir2 family YP_003135326.1 PFAM: ABC transporter; TIGRFAM: daunorubicin resistance ABC transporter ATP-binding subunit YP_003135327.1 PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family YP_003135328.1 PFAM: Bacterial transcriptional activator domain; Transcriptional regulatory protein, C terminal YP_003135329.1 PFAM: ATPase family associated with various cellular activities (AAA); ATPase family associated with various cellular activities (AAA); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain YP_003135336.1 PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: transcriptional activator, putative, Baf family YP_003135337.1 PFAM: Aspartate decarboxylase; TIGRFAM: L-aspartate-alpha-decarboxylase YP_003135338.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_003135339.1 PFAM: Domain of unknown function (DUF2520); Rossmann-like domain YP_003135343.1 PFAM: MerR, DNA binding; MerR family regulatory protein YP_003135344.1 PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_003135345.1 PFAM: Dihydroneopterin aldolase; TIGRFAM: FolB domain; dihydroneopterin aldolase YP_003135346.1 PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_003135347.1 PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I YP_003135348.1 PFAM: Peptidase family M41; ATPase family associated with various cellular activities (AAA); FtsH Extracellular; TIGRFAM: ATP-dependent metalloprotease FtsH YP_003135353.1 PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase YP_003135354.1 PFAM: PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, N-terminal domain YP_003135355.1 PFAM: Uncharacterised conserved protein (DUF2342) YP_003135356.1 PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family YP_003135357.1 PFAM: Inorganic pyrophosphatase YP_003135358.1 PFAM: Bacterial transferase hexapeptide (three repeats) YP_003135360.1 TIGRFAM: DNA polymerase III, delta' subunit YP_003135361.1 PFAM: Major Facilitator Superfamily YP_003135363.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_003135365.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_003135366.1 PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase YP_003135372.1 PFAM: Bacterial type II secretion system protein F domain YP_003135373.1 PFAM: Bacterial type II secretion system protein F domain YP_003135374.1 PFAM: Type II/IV secretion system protein YP_003135376.1 TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like YP_003135377.1 PFAM: Glycosyl hydrolase family 3 N terminal domain; Glycosyl hydrolase family 3 C terminal domain YP_003135378.1 PFAM: Protein of unknown function (DUF1343); TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence YP_003135379.1 PFAM: Beta-lactamase YP_003135380.1 PFAM: SIS domain; Helix-turn-helix domain, rpiR family YP_003135381.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_003135383.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_003135385.1 PFAM: Ykud domain YP_003135387.1 PFAM: Integral membrane protein DUF125 YP_003135388.1 PFAM: Protein of unknown function (DUF1469) YP_003135389.1 PFAM: alpha/beta hydrolase fold YP_003135390.1 PFAM: Colicin V production protein; Trypsin YP_003135391.1 PFAM: NUDIX domain YP_003135392.1 PFAM: AhpC/TSA family YP_003135393.1 PFAM: Iron-sulfur binding domain of endonuclease III; Helix-hairpin-helix motif; TIGRFAM: endonuclease III YP_003135395.1 PFAM: Cyclic nucleotide-binding domain; Bacterial regulatory proteins, crp family YP_003135396.1 PFAM: Major Facilitator Superfamily YP_003135397.1 PFAM: Metallo-beta-lactamase superfamily YP_003135398.1 PFAM: NUDIX domain YP_003135401.1 PFAM: Endoribonuclease L-PSP YP_003135403.1 PFAM: Anion-transporting ATPase YP_003135404.1 PFAM: Anion-transporting ATPase YP_003135405.1 PFAM: Transcription factor WhiB YP_003135406.1 PFAM: Transglycosylase; Penicillin binding protein transpeptidase domain YP_003135407.1 PFAM: Calcineurin-like phosphoesterase YP_003135408.1 PFAM: Methyltransferase domain YP_003135409.1 PFAM: Prolyl oligopeptidase family YP_003135410.1 PFAM: Ferritin-like domain YP_003135411.1 PFAM: NADPH-dependent FMN reductase YP_003135412.1 PFAM: alpha/beta hydrolase fold YP_003135414.1 PFAM: Ferric uptake regulator family YP_003135415.1 PFAM: Major Facilitator Superfamily YP_003135417.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_003135418.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_003135419.1 PFAM: Nitroreductase family YP_003135421.1 PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase, yeast type YP_003135423.1 PFAM: HTH domain YP_003135424.1 PFAM: short chain dehydrogenase YP_003135425.1 PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_003135426.1 PFAM: CoA-transferase family III YP_003135427.1 PFAM: Integral membrane protein DUF6 YP_003135428.1 PFAM: Oligopeptide/dipeptide transporter, C-terminal region; ABC transporter; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_003135429.1 PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region YP_003135430.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003135431.1 PFAM: Binding-protein-dependent transport system inner membrane component YP_003135432.1 PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_003135434.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_003135435.1 PFAM: Uncharacterised BCR, YbaB family COG0718; TIGRFAM: conserved hypothetical protein TIGR00103 YP_003135436.1 PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, subunits gamma and tau YP_003135439.1 PFAM: Helix-turn-helix YP_003135442.1 PFAM: Domain of unknown function (DUF397) YP_003135444.1 PFAM: Helix-turn-helix YP_003135445.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_003135446.1 PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family YP_003135447.1 PFAM: TrkA-N domain; TrkA-C domain YP_003135448.1 PFAM: Cobalamin-independent synthase, Catalytic domain YP_003135450.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_003135451.1 PFAM: haloacid dehalogenase-like hydrolase; Heavy-metal-associated domain; E1-E2 ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-(or silver)-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_003135452.1 PFAM: Heavy-metal-associated domain; TIGRFAM: copper ion binding protein YP_003135453.1 PFAM: Uncharacterised BCR, COG1937 YP_003135456.1 PFAM: FtsK/SpoIIIE family YP_003135462.1 PFAM: Bacterial regulatory proteins, luxR family YP_003135463.1 PFAM: LGFP repeat; PKD domain YP_003135464.1 PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_003135466.1 PFAM: Peptidase family M20/M25/M40; TIGRFAM: amidohydrolase YP_003135467.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_003135469.1 PFAM: Bacterial membrane protein of unknown function (DUF893) YP_003135470.1 PFAM: MarR family YP_003135471.1 PFAM: ABC transporter YP_003135474.1 PFAM: Aldehyde dehydrogenase family; TIGRFAM: succinate-semialdehyde dehydrogenase YP_003135476.1 PFAM: Glutaredoxin YP_003135477.1 TIGRFAM: conserved hypothetical protein TIGR00026 YP_003135478.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135479.1 PFAM: OsmC-like protein YP_003135480.1 PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain YP_003135481.1 PFAM: PAS fold; PAS fold; GGDEF domain; PAS fold; EAL domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; PAS domain S-box YP_003135482.1 PFAM: Uncharacterised ACR, YkgG family COG1556 YP_003135483.1 PFAM: Uncharacterised ACR, YkgG family COG1556; TIGRFAM: 2[4Fe-4S] protein, putative YP_003135484.1 PFAM: Cysteine-rich domain YP_003135485.1 PFAM: YceI-like domain YP_003135489.1 PFAM: 'Cold-shock' DNA-binding domain YP_003135490.1 PFAM: Ykud domain YP_003135491.1 PFAM: Thioesterase superfamily YP_003135492.1 PFAM: Calcineurin-like phosphoesterase YP_003135493.1 PFAM: Protein kinase domain YP_003135494.1 PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_003135496.1 PFAM: Thioesterase superfamily; TIGRFAM: conserved hypothetical protein TIGR00051 YP_003135500.1 PFAM: Peptidase family M48 YP_003135501.1 PFAM: Penicillinase repressor YP_003135502.1 PFAM: Domain of unknown function (DUF1963) YP_003135505.1 PFAM: MMPL family; TIGRFAM: Transport protein YP_003135506.1 PFAM: MarR family YP_003135507.1 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines YP_003135513.1 PFAM: Glycosyl transferase family 2 YP_003135514.1 PFAM: ATP-grasp domain YP_003135516.1 PFAM: Carbamoyltransferase YP_003135518.1 PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1 YP_003135519.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Nitrate and nitrite sensing YP_003135520.1 PFAM: Roadblock/LC7 domain YP_003135521.1 PFAM: Protein of unknown function (DUF742) YP_003135522.1 PFAM: Conserved hypothetical ATP binding protein YP_003135523.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_003135524.1 TIGRFAM: aromatic prenyltransferase, DMATS type YP_003135528.1 PFAM: Integral membrane protein DUF6 YP_003135530.1 PFAM: Dihydrouridine synthase (Dus); TIGRFAM: putative TIM-barrel protein, nifR3 family YP_003135531.1 PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_003135532.1 PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU YP_003135533.1 PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate ABC transporter, phosphate-binding protein YP_003135534.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstC YP_003135535.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA YP_003135536.1 PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter, ATP-binding protein YP_003135537.1 PFAM: Acetyltransferase (GNAT) family; TIGRFAM: mycothiol biosynthesis acetyltransferase YP_003135538.1 PFAM: Transcriptional regulatory protein, C terminal YP_003135542.1 PFAM: Rhodanese-like domain YP_003135543.1 PFAM: Protein of unknown function (DUF1416) YP_003135544.1 PFAM: Domain of unknown function (DUF1794) YP_003135545.1 PFAM: Aminotransferase class IV YP_003135546.1 PFAM: Aminomethyltransferase folate-binding domain; TIGRFAM: folate-binding protein YgfZ YP_003135548.1 PFAM: L-asparaginase II YP_003135551.1 PFAM: Oxidoreductase family, NAD-binding Rossmann fold YP_003135552.1 PFAM: Integral membrane protein DUF112 YP_003135554.1 PFAM: Bordetella uptake gene (bug) product YP_003135555.1 PFAM: PAS fold; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003135556.1 PFAM: Response regulator receiver domain YP_003135557.1 PFAM: RF-1 domain YP_003135558.1 PFAM: AIR synthase related protein, C-terminal domain; AIR synthase related protein, N-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase YP_003135559.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_003135561.1 PFAM: Domain of unknown function (DUF397) YP_003135565.1 PFAM: Glycosyl hydrolases family 25 YP_003135569.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_003135570.1 TIGRFAM: phosphoribosylformylglycinamidine synthase I YP_003135571.1 PFAM: Phosphoribosylformylglycinamidine (FGAM) synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase, purS protein YP_003135573.1 PFAM: Aldehyde dehydrogenase family YP_003135574.1 PFAM: Metallo-beta-lactamase superfamily YP_003135575.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_003135576.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135578.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-E family YP_003135579.1 PFAM: Beta-eliminating lyase YP_003135580.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase; haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_003135582.1 PFAM: Aminotransferase class I and II YP_003135583.1 PFAM: Proteins of 100 residues with WXG; Transglycosylase SLT domain YP_003135588.1 PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase YP_003135589.1 PFAM: Glycerophosphoryl diester phosphodiesterase family YP_003135590.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_003135592.1 PFAM: Secretory lipase YP_003135593.1 PFAM: Domain of unknown function (DUF1994) YP_003135595.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_003135597.1 PFAM: short chain dehydrogenase YP_003135598.1 PFAM: Pyridoxamine 5'-phosphate oxidase YP_003135599.1 PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-E family YP_003135600.1 PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase YP_003135602.1 PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD YP_003135603.1 PFAM: SNARE associated Golgi protein YP_003135605.1 PFAM: pfkB family carbohydrate kinase YP_003135606.1 PFAM: Periplasmic binding proteins and sugar binding domain of the LacI family; Bacterial regulatory proteins, lacI family YP_003135607.1 PFAM: Catalytic LigB subunit of aromatic ring-opening dioxygenase YP_003135608.1 PFAM: Aromatic-ring-opening dioxygenase LigAB, LigA subunit; TIGRFAM: protocatechuate 4,5-dioxygenase, alpha subunit YP_003135609.1 PFAM: Muconolactone delta-isomerase; TIGRFAM: muconolactone delta-isomerase YP_003135611.1 PFAM: Demethylmenaquinone methyltransferase; TIGRFAM: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase YP_003135612.1 PFAM: GlcNAc-PI de-N-acetylase YP_003135613.1 PFAM: Bacterial regulatory proteins, luxR family; Response regulator receiver domain YP_003135614.1 PFAM: GAF domain; PAS fold; Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box YP_003135615.1 PFAM: Major Facilitator Superfamily YP_003135616.1 PFAM: Aldehyde dehydrogenase family YP_003135617.1 PFAM: Protein of unknown function (DUF574) YP_003135618.1 PFAM: SpoU rRNA Methylase family YP_003135620.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_003135621.1 PFAM: short chain dehydrogenase YP_003135624.1 PFAM: C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB YP_003135625.1 PFAM: Oxidoreductase FAD-binding domain; Globin; Oxidoreductase NAD-binding domain YP_003135626.1 PFAM: MerR family regulatory protein YP_003135627.1 PFAM: DnaJ domain; DnaJ C terminal region; DnaJ central domain (4 repeats); TIGRFAM: chaperone protein DnaJ YP_003135628.1 PFAM: GrpE YP_003135629.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_003135631.1 PFAM: Phosphatidylethanolamine-binding protein; TIGRFAM: conserved hypothetical protein TIGR00481 YP_003135632.1 PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator YP_003135633.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135634.1 PFAM: Small Multidrug Resistance protein YP_003135635.1 PFAM: Cysteine-rich domain YP_003135636.1 PFAM: Protein of unknown function (DUF742) YP_003135637.1 PFAM: Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, C-terminal domain YP_003135638.1 PFAM: SCP-like extracellular protein YP_003135639.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_003135641.1 PFAM: Pyridoxamine 5'-phosphate oxidase YP_003135643.1 PFAM: VanZ like family YP_003135644.1 PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_003135645.1 PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain YP_003135648.1 PFAM: Chaperonin 10 Kd subunit YP_003135649.1 PFAM: NHL repeat; AhpC/TSA family YP_003135651.1 PFAM: ABC transporter YP_003135652.1 PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_003135653.1 PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_003135654.1 PFAM: Peptidase family M20/M25/M40 YP_003135655.1 PFAM: Dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, alpha subunit YP_003135656.1 PFAM: Transketolase, pyrimidine binding domain; Transketolase, C-terminal domain YP_003135657.1 PFAM: Biotin-requiring enzyme; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain YP_003135658.1 PFAM: FxsA cytoplasmic membrane protein YP_003135659.1 PFAM: Bacterial regulatory proteins, tetR family YP_003135663.1 PFAM: MaoC like domain YP_003135664.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_003135665.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_003135669.1 PFAM: ABC transporter; TIGRFAM: daunorubicin resistance ABC transporter ATP-binding subunit YP_003135670.1 PFAM: ABC-2 type transporter; TIGRFAM: ABC transporter efflux protein, DrrB family YP_003135671.1 PFAM: DoxX YP_003135674.1 PFAM: Polysaccharide deacetylase YP_003135675.1 PFAM: Asparaginase YP_003135676.1 PFAM: Luciferase-like monooxygenase YP_003135677.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP YP_003135679.1 PFAM: GTPase of unknown function; TIGRFAM: GTP-binding conserved hypothetical protein YP_003135681.1 PFAM: GTPase of unknown function YP_003135682.1 PFAM: ABC transporter YP_003135685.1 PFAM: Putative methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase YP_003135686.1 PFAM: Predicted permease YP_003135687.1 PFAM: ABC transporter YP_003135688.1 PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003135689.1 PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_003135690.1 PFAM: Amidohydrolase family YP_003135692.1 PFAM: ABC transporter YP_003135693.1 PFAM: Bacterial regulatory proteins, gntR family YP_003135694.1 PFAM: Dyp-type peroxidase family; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; Tat-translocated enzyme; Dyp-type peroxidase family YP_003135695.1 PFAM: Protein of unknown function (DUF461) YP_003135697.1 PFAM: short chain dehydrogenase YP_003135698.1 PFAM: Bacterial protein of unknown function (DUF839); TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_003135699.1 PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED YP_003135700.1 PFAM: Myo-inositol-1-phosphate synthase; TIGRFAM: inositol 1-phosphate synthase, Actinobacterial type YP_003135701.1 PFAM: Transcriptional regulator PadR-like family YP_003135703.1 PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase YP_003135705.1 PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1) YP_003135708.1 PFAM: Ribosomal protein S6; TIGRFAM: ribosomal protein S6 YP_003135709.1 PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_003135710.1 PFAM: Ribosomal protein S18; TIGRFAM: ribosomal protein S18 YP_003135711.1 PFAM: Ribosomal protein L9, C-terminal domain; Ribosomal protein L9, N-terminal domain; TIGRFAM: ribosomal protein L9 YP_003135716.1 PFAM: DnaB-like helicase C terminal domain; DnaB-like helicase N terminal domain; TIGRFAM: replicative DNA helicase YP_003135717.1 PFAM: Catalytic LigB subunit of aromatic ring-opening dioxygenase YP_003135718.1 PFAM: Domain of unknown function DUF20 YP_003135719.1 PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_003135720.1 PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_003135721.1 PFAM: Domain of unknown function (DUF1707) YP_003135722.1 PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; PEP-utilising enzyme, mobile domain; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase YP_003135723.1 PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase YP_003135724.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_003135726.1 PFAM: Uncharacterized ACR, COG1678 YP_003135728.1 PFAM: HD domain; Poly A polymerase head domain; TIGRFAM: tRNA adenylyltransferase; uncharacterized domain HDIG YP_003135729.1 PFAM: NUDIX domain YP_003135730.1 TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type YP_003135731.1 PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN YP_003135733.1 PFAM: Sigma-70 region 2; Sigma-70, region 4; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_003135735.1 PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase YP_003135736.1 PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_003135737.1 PFAM: N-acetylmuramoyl-L-alanine amidase; Putative peptidoglycan binding domain YP_003135738.1 PFAM: Acetyltransferase (GNAT) family YP_003135739.1 PFAM: Aminotransferase class I and II YP_003135740.1 PFAM: ATP-grasp domain; D-ala D-ala ligase N-terminus; TIGRFAM: D-alanine--D-alanine ligase YP_003135741.1 PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins YP_003135742.1 PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_003135743.1 PFAM: Glucose inhibited division protein; TIGRFAM: glucose-inhibited division protein B YP_003135744.1 PFAM: R3H domain YP_003135745.1 PFAM: 60Kd inner membrane protein YP_003135746.1 PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein TIGR00278 YP_003135747.1 PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial YP_003135748.1 PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type