-- dump date 20140620_042535 -- class Genbank::CDS -- table cds_function -- id function YP_007034213.1 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings,including catenanes and knotted rings YP_007034214.1 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings,including catenanes and knotted rings YP_007034231.1 Cell division protein FtsI/penicillin-binding protein 2 YP_007034233.1 The only predicted protein phosphatase in M.tuberculosis, it dephosphorylates at least 5 protein kinases (pknA, pknB, pknD, pknE and pknF) and the penicillin-binding protein PBPA YP_007034234.1 FOG: FHA domain YP_007034235.1 FOG: FHA domain YP_007034265.1 Catalyzes the conversion of UDP-glucose into UDP- glucuronate, one of the precursors of teichuronic acid YP_007034270.1 GDP-D-mannose dehydratase YP_007034272.1 Glycosyltransferase YP_007034275.1 Glycosyltransferase YP_007034310.1 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_007034313.1 Iron-storage protein (Potential) YP_007034339.1 Member of the two-component regulatory system devR/devS (dosR/dosS) involved in onset of the dormancy response. When phosphorylated binds the promoter of at least its own and Acr (hspX) gene in response to hypoxia. Activates its own transcription under hypoxic but not aerobic conditions, probably binds as a dimer to tandem binding sites within the devR and hspX promoters. Accepts a phosphate group from devS (dosS) and from dosT YP_007034365.1 Glycosyltransferases involved in cell wall biogenesis YP_007034368.1 Glycosyltransferases involved in cell wall biogenesis YP_007034372.1 Predicted glycosyltransferases YP_007034376.1 Predicted glycosyltransferases YP_007034377.1 May form an ATP-driven O-antigen export apparatus, in association with RfbD YP_007034383.1 May be involved in the generation of reactive oxygen species (ROS). Has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4- naphtoquinone. Has low NADPH-dependent diamine reductase activity (in vitro) YP_007034392.1 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase YP_007034397.1 Involved in poly-3-hydroxybutyrate degradation. Activates acetoacetate to acetoacetyl-CoA YP_007034398.1 Is a recombinase (or integrase), catalyzing the cutting and rejoining of the recombining DNA molecules YP_007034432.1 Cytosine/adenosine deaminases YP_007034437.1 Predicted extracellular nuclease YP_007034443.1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity YP_007034449.1 Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane YP_007034451.1 This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though,unlike OPP, is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system YP_007034452.1 This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though,unlike OPP, is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system YP_007034456.1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) YP_007034460.1 Aspartokinases YP_007034466.1 Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_007034480.1 membrane carboxypeptidase (penicillin-binding protein) YP_007034506.1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain YP_007034514.1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA),respectively YP_007034536.1 The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another YP_007034552.1 Hypoxanthine-guaninephosphoribosyltransferase YP_007034568.1 Panthothenate synthetase YP_007034601.1 FOG: GGDEF domain YP_007034602.1 Permeases of the major facilitator superfamily YP_007034604.1 Predicted membrane protein involved in D-alanine export YP_007034605.1 rRNA methylases YP_007034607.1 Predicted hydrolase (HAD superfamily) YP_007034608.1 Predicted flavin-nucleotide-binding protein YP_007034610.1 4-diphosphocytidyl-2-methyl-D- erithritolsynthase YP_007034611.1 Transcriptional regulators, similar to M. xanthus CarD YP_007034615.1 Trehalose-6-phosphate synthase YP_007034617.1 Predicted integral membrane protein YP_007034634.1 Transcriptional regulator/sugar kinase YP_007034636.1 Predicted N-acetylglucosamine kinase YP_007034653.1 Exhibits dehydratase activity specific for L-threo-3- hydroxyaspartate YP_007034654.1 Hydrolysis of proteins with specificity similar to chymotrypsin. May be specialized for the degradation of chitin- linked proteins. Has a primary specificity for large aliphatic or aromatic amino acids YP_007034655.1 Signal transduction histidine kinase YP_007034663.1 Predicted O-methyltransferase YP_007034692.1 Aerobic-type carbon monoxide dehydrogenase,large subunit, CoxL/CutL homolog YP_007034711.1 In addition to the NAD-dependent oxidative decarboxylation of L-malate, the enzyme catalyzes the decarboxylation of oxaloacetate YP_007034741.1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems YP_007034770.1 Involved in the degradation of long-chain fatty acids YP_007034786.1 Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) YP_007034844.1 Protein related to penicillin acylase YP_007034870.1 Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA,qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration YP_007034889.1 Hydrolysis of proteins with specificity similar to chymotrypsin. May be specialized for the degradation of chitin- linked proteins. Has a primary specificity for large aliphatic or aromatic amino acids YP_007034893.1 Dolichyl-phosphate-mannose--protein O-mannosyl transferase YP_007034899.1 Mg-dependent DNase YP_007034906.1 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase YP_007034932.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_007034936.1 Cytochrome P450 YP_007034946.1 Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system YP_007034947.1 This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though,unlike OPP, is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system YP_007034975.1 Involved in the degradation of long-chain fatty acids YP_007034976.1 Lysophospholipase L1 YP_007034989.1 Highly conserved protein containing a thioredoxin domain YP_007035004.1 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs YP_007035016.1 Penicillin tolerance protein YP_007035052.1 This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though,unlike OPP, is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system YP_007035058.1 Aspartate/tyrosine/aromatic aminotransferase YP_007035059.1 Tetrahydrodipicolinate N-succinyltransferase YP_007035060.1 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases YP_007035078.1 Glycosyltransferase YP_007035081.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_007035131.1 Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps: first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP),followed by sulfur transfer to give CysO-thiocarboxylate (CysO-COSH) (Probable). The sulfur source is unknown YP_007035164.1 Geranylgeranyl pyrophosphate synthase YP_007035186.1 Specifically catalyzes the removal of N-terminal proline residues from peptides YP_007035190.1 Confers resistance to ethidium bromide. Requires lprG lipoprotein for normal function YP_007035193.1 Glycosyltransferase YP_007035227.1 Part of the ABC transporter FtsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KinC, the RapA phosphatase and the Spo0A sporulation protein YP_007035234.1 Glycosyltransferases involved in cell wall biogenesis YP_007035262.1 Predicted ATPase YP_007035271.1 Glycosyltransferases involved in cell wall biogenesis YP_007035286.1 May be involved in active puromycin efflux energized by a proton-dependent electrochemical gradient. In addition, it could be implicated in secreting N-acetylpuromycin, the last intermediate of the puromycin biosynthesis pathway, to the environment YP_007035304.1 ABC-type phosphate transport system,periplasmic component YP_007035318.1 DNA-binding transcriptional activator of the SARP family YP_007035319.1 FOG: TPR repeat YP_007035321.1 Rhs family protein YP_007035326.1 Neuraminidase (sialidase) YP_007035327.1 DNA-binding transcriptional activator of the SARP family YP_007035328.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007035330.1 Permeases of the major facilitator superfamily YP_007035331.1 Predicted flavoprotein YP_007035332.1 NADPH:quinone reductase and related Zn-dependent oxidoreductases YP_007035333.1 DNA-binding HTH domain-containing proteins YP_007035334.1 N-acetyl-beta-hexosaminidase YP_007035359.1 Nicotinic acid phosphoribosyltransferase YP_007035363.1 Protease that hydrolyzes the covalent CysO-cysteine adduct synthesized by CysM to release L-cysteine and regenerate CysO YP_007035365.1 Catalyzes the formation of a covalent CysO-cysteine adduct via a sulfur transfer, using the thiocarboxylated sulfur carrier protein CysO-COSH as sulfur donor and O-phospho-L-serine (OPS) as sulfur acceptor. Can also use sodium sulfide as sulfur donor in vitro, albeit with less efficiency, but not thiosulfate or thio-nitro-benzoate. O-acetylserine (OAS) is a very poor substrate in comparison with OPS. May be of particular importance for cysteine biosynthesis in the persistent phase of M.tuberculosis YP_007035418.1 uncharacterized conserved protein YP_007035440.1 Essential for pSAM2 replication YP_007035449.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_007035457.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_007035464.1 FOG: TPR repeat YP_007035485.1 Predicted transcriptional regulators YP_007035493.1 N-acetyl-beta-hexosaminidase YP_007035500.1 Predicted metal-dependent hydrolase with the TIM-barrel fold YP_007035503.1 uncharacterized protein conserved in cyanobacteria YP_007035517.1 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP YP_007035522.1 Involved in arginine catabolism by converting L-glutamate, into 2-oxoglutarate, which is then channeled into the tricarboxylic acid cycle. Can also utilize other amino acids of the glutamate family YP_007035525.1 Glycosidases YP_007035527.1 Transcription repressor involved in control of expression of alpha-amylase and chitinase genes and of actinorhodin production YP_007035533.1 Required for the transposition of the insertion element (Potential) YP_007035542.1 Aminopeptidase with broad substrate specificity to several peptides. Shows strong preference for leucine but cleaves also next to Arg and lysine in peptide-bond-containing substrates YP_007035543.1 Predicted oxidoreductase YP_007035577.1 Protease subunit of ATP-dependent Clp proteases YP_007035578.1 Protease subunit of ATP-dependent Clp proteases YP_007035609.1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate YP_007035622.1 Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline YP_007035653.1 uncharacterized protein conserved in cyanobacteria YP_007035658.1 Catalyzes the hydrolysis of the ester bond between the phosphatidic acid and alcohol moieties of phospholipids. Can catalyze a transphosphatidylation reaction in the presence of high concentrations of primary alcohols. Has also phosphatase activity toward p-nitrophenyl phosphate YP_007035659.1 Dioxygenases related to 2-nitropropane dioxygenase YP_007035668.1 Enoyl-CoA hydratase/carnithine racemase YP_007035680.1 Sulfite reductase, beta subunit (hemoprotein) YP_007035722.1 DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis YP_007035735.1 Glycosyltransferases, probably involved in cell wall biogenesis YP_007035743.1 Predicted drug exporters of the RND superfamily YP_007035746.1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane YP_007035764.1 ABC-type multidrug transport system, ATPase and permease components YP_007035765.1 ABC-type bacteriocin/lantibiotic exporters,contain an N-terminal double-glycine peptidase domain YP_007035767.1 Cation transport ATPase YP_007035768.1 3-oxoacyl-(acyl-carrier-protein) synthase YP_007035770.1 3-oxoacyl-[acyl-carrier-protein] synthase III YP_007035771.1 (acyl-carrier-protein) S-malonyltransferase YP_007035772.1 Predicted transcriptional regulators YP_007035773.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007035795.1 The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) YP_007035799.1 Catalyzes the reversible transfers of an amino group from glutamate to the alpha-ketoacid of the respective amino acid in the final step in the biosynthesis of branchedchain amino acids. The amino acids can be ranked in the following order with respect to their efficiency as amino donor: Leu > Ile > Val YP_007035801.1 NaMN:DMB phosphoribosyltransferase YP_007035804.1 Probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit YP_007035822.1 Component of the menaquinol-cytochrome c reductase complex YP_007035823.1 Component of the ubiquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein YP_007035825.1 Transcriptional regulators YP_007035830.1 Glycosyltransferase YP_007035831.1 Predicted ATPase YP_007035838.1 Required for glucose repression of many different genes YP_007035846.1 Phytoene/squalene synthetase YP_007035848.1 Phytoene dehydrogenase and related proteins YP_007035849.1 Geranylgeranyl pyrophosphate synthase YP_007035871.1 Uncharacterized conserved protein, contains double-stranded beta-helix domain YP_007035875.1 predicted phosphatases YP_007035905.1 Part of the binding-protein-dependent transport system for glutamate. Probably responsible for energy coupling to the transport system YP_007035943.1 Probably part of the phnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane YP_007035948.1 RNA ligase that mediates the joining of broken tRNA-like stem-loop structures in case of tRNA damage. Probably participates to tRNA restriction-repair by ligating broken tRNA-like stem-loop structures with 2',3'-cyclic phosphate and 5'-OH ends to form a splice junction with a 2'-OH, 3',5'-phosphodiester YP_007035950.1 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP YP_007035958.1 Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism YP_007035959.1 Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism. CutR suppresses a defective melC1 gene,encoding a putative copper-transfer gene, probably by altering copper metabolism YP_007035970.1 It functions in the generation of fumarate for use as an anaerobic electron acceptor YP_007035974.1 Putative transcriptional regulator YP_007035987.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium YP_007035988.1 Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor. GTP, UTP and CTP can replace ATP as phosphoryl donor YP_007036008.1 Deoxyxylulose-5-phosphate synthase YP_007036010.1 Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism. CutR suppresses a defective melC1 gene,encoding a putative copper-transfer gene, probably by altering copper metabolism YP_007036016.1 AraC-type DNA-binding domain-containing proteins YP_007036017.1 predicted nucleoside-diphosphate-sugar epimerases YP_007036038.1 uncharacterized protein containing caspase domain YP_007036056.1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX YP_007036081.1 Uncharacterized protein, contains Trp-Asp (WD) repeat YP_007036083.1 predicted permease, DMT superfamily YP_007036092.1 uncharacterized protein conserved in bacteria YP_007036094.1 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_007036146.1 Predicted transcriptional regulators YP_007036184.1 The FAS-operon encodes genes involved in cytokinin production and in host plant fasciation (leafy gall) YP_007036215.1 Integrase YP_007036245.1 Predicted ATPase YP_007036259.1 Purine-nucleoside phosphorylase YP_007036268.1 Transposase and inactivated derivatives YP_007036296.1 Signal transduction histidine kinase YP_007036315.1 Essential enzyme that catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain of fatty acids YP_007036326.1 Acts on both enantiomers of limonene by their NAD- dependent epoxidation at the 1,2 double bond forming limonene-1,2- epoxide YP_007036331.1 Catalyzes aldol condensation between L-aspartate-4- semialdehyde (ASA) and dihydroxyacetone phosphate (DHAP), to form 2-amino-4,5-dihydroxy-6-one-heptanoic acid-7-phosphate YP_007036332.1 Catalyzes the cyclization of 2-amino-4,5-dihydroxy-6- one-heptanoic acid-7-phosphate to yield 3-amino-4-hydroxybenzoic acid (3,4-AHBA) YP_007036336.1 Global regulatory protein for secondary metabolite formation YP_007036361.1 Glycosyltransferases involved in cell wall biogenesis YP_007036400.1 Glycosyltransferases, probably involved in cell wall biogenesis YP_007036416.1 predicted ATPase YP_007036429.1 Permeases of the major facilitator superfamily YP_007036430.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036431.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036432.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036433.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036434.1 Predicted carbamoyl transferase, NodU family YP_007036436.1 Probable taurine catabolism dioxygenase YP_007036437.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036439.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036440.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036442.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036443.1 Transcriptional regulator YP_007036444.1 Rhs family protein YP_007036469.1 Part of the ABC transporter complex IrtAB involved in iron import. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation. Required for replication in human macrophages and in mouse lungs YP_007036470.1 Part of the ABC transporter complex IrtAB involved in iron import. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation. Required for replication in human macrophages and in mouse lungs YP_007036480.1 Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) YP_007036483.1 ABC-type Fe3+-hydroxamate transport system YP_007036517.1 ABC-type antimicrobial peptide transport system, ATPase component YP_007036529.1 ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_007036531.1 Glutamate decarboxylase and related PLP-dependent proteins YP_007036549.1 77 Permeases of the major facilitator superfamily YP_007036592.1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine YP_007036613.1 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP YP_007036637.1 4.2.A.1 : The Major Facilitator Superfamily (MFS) YP_007036647.1 Involved in the bioreductive activation of the prodrug PA-824 (nitroimidazo-oxazine) developed for anti-tuberculosis therapy against both replicating and persistent bacteria. It does not interact directly with PA-824 but, rather, provides reduced F420 to an accessory protein (Rv3547), which in turn activates PA- 824 YP_007036654.1 Involved in protein export YP_007036655.1 Involved in protein export YP_007036656.1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family YP_007036687.1 Aqualysin I is a thermophilic alkaline serine protease YP_007036688.1 Aqualysin I is a thermophilic alkaline serine protease YP_007036691.1 Serine proteinase with preferred activity for amino acids with aromatic side groups at the P1' side of the scissible bond YP_007036698.1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family YP_007036699.1 Glycosyltransferases involved in cell wall biogenesis YP_007036700.1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family YP_007036711.1 Sugar transferases involved in lipopolysaccharide synthesis YP_007036713.1 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes YP_007036714.1 dTDP-D-glucose 4,6-dehydratase YP_007036718.1 This membrane protein may function as a sensor protein and may transfer the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of the genes YP_007036725.1 membrane protein involved in the export of O-antigen and teichoic acid YP_007036726.1 Glycosyltransferases involved in cell wall biogenesis YP_007036733.1 Teichoic acid biosynthesis proteins YP_007036734.1 Predicted glycosyltransferases YP_007036741.1 predicted ATPase YP_007036752.1 COG1835: Predicted acyltransferases YP_007036766.1 Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 YP_007036769.1 Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid YP_007036776.1 Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose YP_007036793.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_007036794.1 Signal transduction histidine kinase YP_007036795.1 ABC-type multidrug transport system, ATPase component YP_007036870.1 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_007036872.1 Predicted dienelactone hydrolase YP_007036873.1 Transcriptional regulator YP_007036874.1 Uncharacterized protein conserved in bacteria YP_007036877.1 Permeases of the major facilitator superfamily YP_007036878.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036879.1 Non-ribosomal peptide synthetase modules and related proteins YP_007036880.1 ABC-type Fe3+-hydroxamate transport system,periplasmic component YP_007036881.1 ABC-type Fe3+-hydroxamate transport system,periplasmic component YP_007036882.1 ABC-type Fe3+-siderophore transport system,permease component YP_007036883.1 ABC-type enterobactin transport system,permease component YP_007036884.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007036885.1 Anthranilate/para-aminobenzoate synthases component I YP_007036886.1 Peptide arylation enzymes YP_007036887.1 Isochorismate hydrolase YP_007036888.1 Polyketide synthase modules and related proteins YP_007036893.1 Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for energy coupling to the transport system (Probable) YP_007036897.1 Lactoylglutathione lyase YP_007036942.1 Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds YP_007036945.1 Catalyzes the CoA transfer from succinate to 3-oxoadipate (beta-ketoadipate) YP_007036962.1 Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate YP_007036971.1 Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system YP_007036976.1 Predicted transcriptional regulators YP_007036998.1 Sugar diacid utilization regulator YP_007037015.1 Required for the transposition of the insertion element (Potential) YP_007037028.1 AraC-type DNA-binding domain-containing proteins YP_007037071.1 Catalyzes the hydroxylation of sodium ML-236B carboxylate to pravastatin YP_007037096.1 Folylpolyglutamate synthase YP_007037141.1 Glycosyltransferase YP_007037143.1 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) YP_007037184.1 Predicted transcriptional regulators YP_007037199.1 Catalyzes the NAD-dependent dehydration of beta-hydroxybutyryl-CoA to acetoacetyl-CoA in vitro at pH 10. Also catalyzes the reverse reaction albeit in a lower pH range of 5.5- 6.5. The reverse reaction is able to use NADPH as well as NADH YP_007037209.1 Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues YP_007037212.1 Catalyzes the acylation to the position 6 of the alpha- 1,2-linked mannose residue of the phosphatidyl-myo-inositol dimannoside (PIM2) or monomannoside (PIM1) YP_007037213.1 Glycosyltransferase YP_007037227.1 4-aminobutyrate aminotransferase and related aminotransferases YP_007037255.1 Not known, probably involved in the catabolism of octane and guaiacol. It displays a weak activity in the O-dealkylation of 7-ethoxycoumarin YP_007037299.1 Involved in the resistance against the antituberculosis drugs isoniazid and ethionamide YP_007037300.1 Catalyzes the ferrous insertion into protoporphyrin IX YP_007037338.1 Transcriptional regulator YP_007037375.1 Part of the pafABC operon, however pafB does not seem to be involved in pupylation or substrate degradation. Appears to play at least a small role in resistance to reactive nitrogen intermediates (RNI) in vitro YP_007037380.1 Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is involved in the biosynthesis of phosphatidylinositol mannosides (PIMs),probably via a role in the biosynthesis of phosphatidylinositol (PI), a PIM precursor, which is derived from phosphatidic acid. Is also able to phosphorylate other various amphipathic lipids of host and bacterial origin in vitro, such as ceramide YP_007037389.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_007037390.1 putative intracellular protease/amidase YP_007037394.1 Glutamate decarboxylase and related PLP-dependent proteins YP_007037395.1 Carboxylesterase type B YP_007037401.1 3-oxoacyl-(acyl-carrier-protein) synthase YP_007037402.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007037404.1 3-oxoacyl-(acyl-carrier-protein) synthase YP_007037407.1 3-oxoacyl-[acyl-carrier protein] reductase YP_007037408.1 2-hydroxychromene-2-carboxylate isomerase YP_007037409.1 Predicted oxidoreductase YP_007037410.1 Uncharacterized ABC-type transport system,ATPase component YP_007037411.1 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component YP_007037412.1 Transcriptional regulator YP_007037413.1 3-oxoacyl-[acyl-carrier-protein] synthase III YP_007037419.1 Acyl-CoA dehydrogenases YP_007037421.1 Pyruvate/2-oxoglutarate dehydrogenase complex,dihydrolipoamide dehydrogenase (E3) component, and related enzymes YP_007037422.1 Predicted ornithine cyclodeaminase,mu-crystallin-like protein YP_007037424.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037425.1 ABC-type multidrug transport system, permease component YP_007037426.1 Cytochrome P450 YP_007037427.1 Uncharacterized protein conserved in bacteria YP_007037428.1 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component YP_007037433.1 Permeases of the major facilitator superfamily YP_007037434.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037435.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037437.1 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding YP_007037475.1 Part of the binding-protein-dependent transport system for citrate-dependent Fe(3+). Probably responsible for energy coupling to the transport system YP_007037515.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_007037516.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037519.1 Predicted unusual protein kinase YP_007037521.1 3-oxoacyl-(acyl-carrier-protein) synthase YP_007037522.1 membrane protease subunits, stomatin/prohibitin family YP_007037523.1 Penicillin tolerance protein YP_007037526.1 Polyketide synthase modules and related proteins YP_007037527.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007037528.1 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases YP_007037530.1 Predicted NAD/FAD-binding protein YP_007037531.1 Cytochrome P450 YP_007037532.1 Esterase/lipase YP_007037535.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_007037536.1 Dioxygenases related to 2-nitropropane dioxygenase YP_007037537.1 Polyketide synthase modules and related proteins YP_007037539.1 Choline dehydrogenase and related flavoproteins YP_007037540.1 Poly(3-hydroxyalkanoate) synthetase YP_007037541.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007037543.1 3-oxoacyl-[acyl-carrier-protein] synthase III YP_007037544.1 Polyketide synthase modules and related proteins YP_007037545.1 3-oxoacyl-[acyl-carrier-protein] synthase III YP_007037547.1 Acyl carrier protein YP_007037550.1 Predicted O-methyltransferase YP_007037572.1 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP YP_007037573.1 Part of the ABC transporter complex drrAB involved in daunorubicin and doxorubicin resistance. Probably responsible for the translocation of the substrate across the membrane YP_007037584.1 predicted aminopeptidases YP_007037585.1 Cytochrome P450 YP_007037591.1 Transforms 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) into 5-carboxymethyl-2-hydroxy-muconic acid (CHM) YP_007037592.1 Dihydrodipicolinate synthase/N-acetylneuraminate lyase YP_007037615.1 Oxidizes histamine. Other amines including phenethylamine, tyramine, tryptamine, putrescine, and benzylamine also serve as substrate YP_007037654.1 Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system YP_007037661.1 Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism YP_007037666.1 4.3.A.1.m : membrane component YP_007037667.1 4.3.A.1 : The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases YP_007037673.1 Possible cation transporter YP_007037686.1 Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_007037708.1 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases YP_007037709.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037710.1 Polyketide synthase modules and related proteins YP_007037711.1 3-hydroxyacyl-CoA dehydrogenase YP_007037713.1 Acyl-CoA dehydrogenases YP_007037714.1 3-oxoacyl-[acyl-carrier-protein] synthase III YP_007037716.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037717.1 Permeases of the major facilitator superfamily YP_007037718.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases YP_007037719.1 3-oxoacyl-[acyl-carrier-protein] synthase III YP_007037726.1 SAM-dependent methyltransferases YP_007037727.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037728.1 Permeases of the major facilitator superfamily YP_007037729.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037731.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007037732.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037733.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037734.1 Uncharacterized protein conserved in bacteria YP_007037735.1 Predicted phosphohydrolases YP_007037736.1 Transcriptional regulator YP_007037738.1 Glutamate decarboxylase and related PLP-dependent proteins YP_007037739.1 Na+/melibiose symporter and related transporters YP_007037751.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_007037752.1 putative intracellular protease/amidase YP_007037760.1 Predicted dehydrogenases and related proteins YP_007037801.1 Superfamily I DNA and RNA helicases YP_007037879.1 Predicted ATPase YP_007037880.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007037882.1 ABC-type amino acid transport system, permease component YP_007037883.1 ABC-type sugar transport systems, ATPase components YP_007037884.1 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_007037885.1 AraC-type DNA-binding domain-containing proteins YP_007037886.1 AraC-type DNA-binding domain-containing proteins YP_007037887.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_007037888.1 Signal transduction histidine kinase YP_007037889.1 Uncharacterized conserved protein YP_007037890.1 Uncharacterized conserved protein YP_007037891.1 Gluconolactonase YP_007037892.1 Transcriptional regulator YP_007037893.1 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] YP_007037894.1 Permeases of the major facilitator superfamily YP_007037895.1 Predicted aminopeptidases YP_007037897.1 Aminopeptidase N YP_007037898.1 Non-ribosomal peptide synthetase modules and related proteins YP_007037900.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases YP_007037901.1 FOG: WD40 repeat YP_007037902.1 Predicted ATPase YP_007037906.1 Predicted hydrolase (HAD superfamily) YP_007037908.1 Cell wall hydrolyses involved in spore germination YP_007037910.1 ABC-type sugar transport system, permease component YP_007037911.1 ABC-type sugar transport systems, permease components YP_007037912.1 Predicted phosphohydrolases YP_007037913.1 ABC-type sugar transport system, periplasmic component YP_007037914.1 ABC-type sugar transport systems, ATPase components YP_007037915.1 Metal-dependent hydrolases of the beta-lactamase superfamily III YP_007037916.1 UDP-N-acetyl-D-mannosaminuronatedehydrogenase YP_007037917.1 Predicted dehydrogenases and related proteins YP_007037930.1 Transforms O-acetylhomoserine into homocysteine YP_007037934.1 4.3.A.1.m : membrane component YP_007037941.1 Interacts with the two-component regulatory system devR/devS (dosR/dosS) involved in onset of the dormancy response. May act as a direct hypoxia sensor (rather than a redox sensor); the normal state is the oxygenated form, while the deoxy form is probably active for phosphate transfer. May be the secondary sensor for CO. Donates a phosphate group to devR (dosR) YP_007037955.1 Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) YP_007037957.1 predicted transcriptional regulators YP_007037967.1 Member of the two-component regulatory system devR/devS (dosR/dosS) involved in onset of the dormancy response. When phosphorylated binds the promoter of at least its own and Acr (hspX) gene in response to hypoxia. Activates its own transcription under hypoxic but not aerobic conditions, probably binds as a dimer to tandem binding sites within the devR and hspX promoters. Accepts a phosphate group from devS (dosS) and from dosT YP_007037994.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_007037996.1 Glycosyltransferases involved in cell wall biogenesis YP_007037998.1 Metabolism of a number of sulfonylurea herbicides YP_007038007.1 Highly specific for beta-cyano-L-alanine (Ala(CN)). Low activity with 3-phenylpropionitrile (PPN). Not associated with auxin production but may be involved in cyanide detoxification YP_007038013.1 Serine proteinase with preferred activity for amino acids with aromatic side groups at the P1' side of the scissible bond YP_007038051.1 ABC-type antimicrobial peptide transport system, permease component YP_007038052.1 ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_007038053.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_007038054.1 Signal transduction histidine kinase YP_007038057.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain YP_007038058.1 Signal transduction histidine kinase,glucose-6-phosphate specific YP_007038059.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007038060.1 Cytochrome P450 YP_007038061.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007038062.1 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_007038063.1 Permeases of the major facilitator superfamily YP_007038064.1 Uncharacterized conserved protein YP_007038065.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038066.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038067.1 Uncharacterized protein conserved in bacteria YP_007038068.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007038069.1 Aromatic ring hydroxylase YP_007038070.1 Uncharacterized protein conserved in bacteria YP_007038071.1 Predicted O-methyltransferase YP_007038072.1 Polyketide synthase modules and related proteins YP_007038073.1 Cytochrome P450 YP_007038074.1 Acyl-CoA dehydrogenases YP_007038075.1 Cytochrome P450 YP_007038076.1 Pyruvate/2-oxoglutarate dehydrogenase complex,dihydrolipoamide acyltransferase (E2) component, and related enzymes YP_007038077.1 Pyruvate/2-oxoglutarate dehydrogenase complex,dehydrogenase (E1) component, eukaryotic type, beta subunit YP_007038078.1 Pyruvate/2-oxoglutarate dehydrogenase complex,dehydrogenase (E1) component, eukaryotic type, alpha subunit YP_007038079.1 Glutamyl-tRNA reductase YP_007038080.1 Chorismate mutase YP_007038082.1 Choline dehydrogenase and related flavoproteins YP_007038084.1 AraC-type DNA-binding domain-containing proteins YP_007038085.1 Cytochrome P450 YP_007038086.1 Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB YP_007038091.1 Polyketide synthase modules and related proteins YP_007038092.1 Predicted thioesterase YP_007038093.1 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_007038094.1 dTDP-D-glucose 4,6-dehydratase YP_007038095.1 Transcriptional regulator YP_007038097.1 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases YP_007038098.1 Uncharacterized protein conserved in bacteria YP_007038099.1 Uncharacterized conserved protein YP_007038138.1 Possible transporter that might be responsible for the adsorption of amidase substrates or release of their hydrolysis products YP_007038158.1 Involved in the degradation of long-chain fatty acids YP_007038164.1 Probable taurine catabolism dioxygenase YP_007038169.1 3-oxoacyl-(acyl-carrier-protein) synthase YP_007038218.1 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases YP_007038256.1 DNA-binding HTH domain-containing proteins YP_007038258.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007038259.1 Polyketide synthase modules and related proteins YP_007038260.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007038261.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007038262.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases YP_007038263.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases YP_007038264.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007038265.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007038266.1 SAM-dependent methyltransferases YP_007038267.1 ATP-dependent transcriptional regulator YP_007038268.1 AraC-type DNA-binding domain-containing proteins YP_007038269.1 Predicted membrane protein YP_007038270.1 Predicted membrane protein YP_007038271.1 Glycosyltransferases involved in cell wall biogenesis YP_007038280.1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases YP_007038281.1 Threonine dehydrogenase and related Zn-dependent dehydrogenases YP_007038282.1 Uncharacterized protein, putative amidase YP_007038285.1 Glycosyltransferase YP_007038286.1 6-pyruvoyl-tetrahydropterin synthase YP_007038287.1 GTP cyclohydrolase II YP_007038288.1 F0F1-type ATP synthase, subunit a YP_007038289.1 Coenzyme F390 synthetase YP_007038290.1 Histone acetyltransferase HPA2 and related acetyltransferases YP_007038291.1 DNA-binding transcriptional activator of the SARP family YP_007038293.1 Lantibiotic modifying enzyme YP_007038294.1 ABC-type multidrug transport system, ATPase and permease components YP_007038295.1 FAD/FMN-containing dehydrogenases YP_007038296.1 SAM-dependent methyltransferases YP_007038309.1 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP YP_007038321.1 ABC-type cobalt transport system, permease component CbiQ and related transporters YP_007038323.1 GMP synthase - Glutamine amidotransferase domain YP_007038327.1 Aqualysin I is a thermophilic alkaline serine protease YP_007038332.1 Siderophore-interacting protein YP_007038352.1 Predicted RNA polymerase sigma factor containing a TPR repeat domain YP_007038358.1 Not yet known YP_007038365.1 FOG: FHA domain YP_007038399.1 2-polyprenyl-6-methoxyphenol hydroxylase YP_007038404.1 Sugar diacid utilization regulator YP_007038437.1 Removes the amino-terminal methionine from nascent proteins YP_007038464.1 Glycosyltransferases involved in cell wall biogenesis YP_007038468.1 Transcriptional regulator YP_007038513.1 Hydrolyzes the ceramides into sphingosine and free fatty acid at an optimal pH of 8-9 YP_007038571.1 HD-GYP domain YP_007038590.1 Serine/threonine protein kinase YP_007038591.1 Permeases of the major facilitator superfamily YP_007038593.1 Thioredoxin reductase YP_007038595.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007038596.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007038598.1 Uncharacterized low-complexity proteins YP_007038599.1 Predicted transcriptional regulators YP_007038600.1 Uncharacterized protein conserved in bacteria YP_007038603.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007038604.1 Methylase involved in ubiquinone/menaquinone biosynthesis YP_007038605.1 Uncharacterized conserved protein YP_007038606.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007038607.1 Dihydrofolate reductase YP_007038625.1 Beta-lactamase class C and other penicillin binding proteins YP_007038626.1 Transcriptional regulator YP_007038652.1 Predicted glutathione S-transferase YP_007038657.1 FOG: Ankyrin repeat YP_007038658.1 Subtilisin-like serine proteases YP_007038659.1 Cytochrome P450 YP_007038706.1 Superfamily II DNA helicase YP_007038707.1 Tryptophanyl-tRNA synthetase YP_007038708.1 Cyclopropane fatty acid synthase and related methyltransferases YP_007038709.1 Uncharacterized protein conserved in bacteria YP_007038711.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038712.1 Uncharacterized protein conserved in bacteria YP_007038716.1 Predicted iron-dependent peroxidase YP_007038717.1 Nitrous oxidase accessory protein YP_007038722.1 Predicted Zn-dependent protease YP_007038723.1 Fibronectin type 3 domain-containing protein YP_007038724.1 ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_007038725.1 ABC-type Fe3+-siderophore transport system,permease component YP_007038726.1 ABC-type Fe3+-siderophore transport system,permease component YP_007038727.1 ABC-type Fe3+-hydroxamate transport system,periplasmic component YP_007038729.1 Amidases related to nicotinamidase YP_007038733.1 Fe-S oxidoreductase YP_007038734.1 Transcriptional regulator YP_007038735.1 Permeases of the major facilitator superfamily YP_007038736.1 Permeases of the major facilitator superfamily YP_007038737.1 ATP-dependent protease Clp, ATPase subunit YP_007038738.1 Polyketide synthase modules and related proteins YP_007038739.1 Polyketide synthase modules and related proteins YP_007038741.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007038742.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007038743.1 ABC-type multidrug transport system, ATPase and permease components YP_007038745.1 Fe-S oxidoreductase YP_007038746.1 SAM-dependent methyltransferases YP_007038747.1 ABC-type uncharacterized transport system,duplicated ATPase component YP_007038748.1 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_007038749.1 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_007038750.1 ABC-type dipeptide transport system,periplasmic component YP_007038751.1 Dehydrogenases (flavoproteins) YP_007038752.1 3-oxoacyl-(acyl-carrier-protein) synthase YP_007038753.1 Acyl carrier protein YP_007038755.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038757.1 Dioxygenases related to 2-nitropropane dioxygenase YP_007038758.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038759.1 Predicted thioesterase involved in non-ribosomal peptide biosynthesis YP_007038760.1 Adenosylmethionine-8-amino-7- oxononanoateaminotr ansferase YP_007038761.1 Cytochrome P450 YP_007038762.1 ABC-type sugar transport systems, ATPase components YP_007038763.1 ABC-type multidrug transport system, permease component YP_007038765.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007038766.1 3-hydroxy-3-methylglutaryl CoA synthase YP_007038767.1 Acyl carrier protein YP_007038769.1 Polyketide synthase modules and related proteins YP_007038770.1 Polyketide synthase modules and related proteins YP_007038772.1 3-hydroxy-3-methylglutaryl CoA synthase YP_007038773.1 Enoyl-CoA hydratase/carnithine racemase YP_007038774.1 Dioxygenases related to 2-nitropropane dioxygenase YP_007038775.1 Uncharacterized protein conserved in bacteria YP_007038776.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_007038777.1 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_007038780.1 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_007038793.1 Septum formation inhibitor YP_007038797.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_007038800.1 Uncharacterized protein, possibly involved in glyoxylate utilization YP_007038807.1 Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane YP_007038810.1 This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though,unlike OPP, is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system YP_007038837.1 Catalyzes the ortho-cleavage of the aromatic ring of hydroxyquinol YP_007038846.1 predicted lipase YP_007038847.1 Glycosidases YP_007038857.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007038859.1 Predicted GTPase YP_007038861.1 Uncharacterized distant relative of homeotic protein bithoraxoid YP_007038862.1 Signal transduction histidine kinase YP_007038863.1 ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_007038864.1 Enterochelin esterase and related enzymes YP_007038868.1 DNA-binding HTH domain-containing proteins YP_007038869.1 Subtilisin-like serine proteases YP_007038870.1 Cytochrome P450 YP_007038871.1 Monoamine oxidase YP_007038872.1 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases YP_007038874.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007038875.1 Polyketide synthase modules and related proteins YP_007038876.1 Polyketide synthase modules and related proteins YP_007038877.1 4-aminobutyrate aminotransferase and related aminotransferases YP_007038878.1 Polyketide synthase modules and related proteins YP_007038880.1 DNA-binding transcriptional activator of the SARP family YP_007038881.1 ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_007038882.1 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_007038883.1 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_007038884.1 ABC-type dipeptide transport system,periplasmic component YP_007038886.1 Predicted ester cyclase YP_007038887.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007038888.1 Polyketide synthase modules and related proteins YP_007038889.1 Polyketide synthase modules and related proteins YP_007038890.1 Polyketide synthase modules and related proteins YP_007038891.1 Polyketide synthase modules and related proteins YP_007038892.1 DNA-binding HTH domain-containing proteins YP_007038893.1 Dehydrogenases (flavoproteins) YP_007038896.1 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) YP_007038897.1 Permeases of the major facilitator superfamily YP_007038898.1 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) YP_007038899.1 Cytochrome P450 YP_007038900.1 Ca2+/Na+ antiporter YP_007038901.1 Topoisomerase IB YP_007038903.1 Predicted acetyltransferase YP_007038905.1 Predicted membrane protein YP_007038906.1 FOG: HEAT repeat YP_007038907.1 Transcriptional regulator YP_007038908.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007038910.1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain YP_007038912.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007038913.1 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis YP_007038914.1 Cytochrome P450 YP_007038915.1 FOG: WD40 repeat YP_007038916.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038917.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007038918.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038919.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007038920.1 Cytochrome P450 YP_007038922.1 O-Glycosyl hydrolase YP_007038923.1 Cyclopropane fatty acid synthase and related methyltransferases YP_007038925.1 Protease subunit of ATP-dependent Clp proteases YP_007038926.1 Protease subunit of ATP-dependent Clp proteases YP_007038927.1 Predicted transcriptional regulators YP_007038928.1 Monoamine oxidase YP_007038929.1 Monoamine oxidase YP_007038931.1 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase YP_007038933.1 Predicted phosphatase/phosphohexomutase YP_007038934.1 Pyruvate carboxylase YP_007038935.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_007038936.1 Enoyl-CoA hydratase/carnithine racemase YP_007038937.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038938.1 Permeases of the major facilitator superfamily YP_007038939.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038940.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases YP_007038941.1 Polyketide synthase modules and related proteins YP_007038942.1 Non-ribosomal peptide synthetase modules and related proteins YP_007038943.1 Uncharacterized protein conserved in bacteria YP_007038944.1 Transcriptional regulator YP_007038945.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007038946.1 Uncharacterized protein potentially involved in peptidoglycan biosynthesis YP_007038947.1 Beta-glucosidase-related glycosidases YP_007038962.1 Glycosidases YP_007038963.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases YP_007038964.1 Aerobic-type carbon monoxide dehydrogenase,small subunit, CoxS/CutS homolog YP_007038965.1 Aerobic-type carbon monoxide dehydrogenase,middle subunit, CoxM/CutM homolog YP_007038966.1 Aerobic-type carbon monoxide dehydrogenase,large subunit, CoxL/CutL homolog YP_007038967.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007038968.1 Glycosyltransferase YP_007038973.1 Cyclopropane fatty acid synthase and related methyltransferases YP_007038974.1 Uncharacterized conserved protein YP_007038975.1 Leucine-rich repeat (LRR) protein YP_007038976.1 Polyketide synthase modules and related proteins YP_007038977.1 Polyketide synthase modules and related proteins YP_007038978.1 Polyketide synthase modules and related proteins YP_007038979.1 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases YP_007038980.1 Biotin carboxylase YP_007038981.1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) YP_007038982.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_007038984.1 Response regulator containing CheY-like receiver and SARP domains YP_007038985.1 Predicted transcriptional regulators YP_007038986.1 4-aminobutyrate aminotransferase and related aminotransferases YP_007038987.1 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family YP_007038990.1 Acyl-CoA dehydrogenases YP_007038991.1 Cytochrome P450 YP_007038992.1 NAD-dependent aldehyde dehydrogenases YP_007038994.1 Acyl-CoA dehydrogenases YP_007038995.1 Putative ketosteroid isomerase YP_007038996.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_007038997.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_007038998.1 7-keto-8-aminopelargonate synthetase and related enzymes YP_007039005.1 FOG: TPR repeat YP_007039057.1 Esterase/lipase YP_007039058.1 Transcriptional regulator YP_007039059.1 Uncharacterized low-complexity proteins YP_007039063.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007039065.1 Methionine synthase II (cobalamin-independent) YP_007039066.1 Ribonucleotide reductase, alpha subunit YP_007039067.1 Ribonucleotide reductase, beta subunit YP_007039068.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases YP_007039075.1 Positive regulator required for energy stress activation of the sigma-B transcription factor. Could be required for rsbP phosphatase activity YP_007039085.1 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP YP_007039092.1 Catalyzes the formation of 5'adenyl-Trp and tRNA(Trp) but with 5-fold less activity than trpRS. Increases the solubility of the nitric oxide synthase oxygenase (nos), as well as its affinity for substrate L-arginine and its nitric-oxide synthase activity. The complex between trpS2 and nos catalyzes the regioselective nitration of tryptophan at the 4-position YP_007039095.1 predicted nucleoside-diphosphate-sugar epimerases YP_007039097.1 Catalyzes the reduction of N-ethylmaleimide (NEM) to N- ethylsuccinimide YP_007039098.1 DNA-binding HTH domain-containing proteins YP_007039115.1 Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism. CutR suppresses a defective melC1 gene,encoding a putative copper-transfer gene, probably by altering copper metabolism YP_007039117.1 Hydrolyzes the cellular pool of D-Ala-D-Ala dipeptides. May play a role in immunity or defense against glycopeptide antibiotics (perhaps at a moderate level) in the soil environment. Might confer vancomycin resistance to S.coelicolor YP_007039119.1 Required for high-level resistance to glycopeptides antibiotics. Catalyzes the reduction of 2-keto acids to 2-D- hydroxy acids that give rise to peptidoglycan precursors that terminate in the depsipeptide D-alanine-2-lactate rather than the dipeptide D-alanine-D-alanine thus preventing vancomycin binding YP_007039162.1 Glycosyltransferase YP_007039167.1 Not known, probably involved in the catabolism of octane and guaiacol. It displays a weak activity in the O-dealkylation of 7-ethoxycoumarin YP_007039168.1 Involved in 6-O-carbamoylation of Nod-factors YP_007039170.1 Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine YP_007039188.1 Nucleoside-diphosphate-sugar epimerases YP_007039190.1 Glycosyltransferases involved in cell wall biogenesis YP_007039191.1 ADP-heptose:LPS heptosyltransferase YP_007039195.1 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase YP_007039197.1 Glycosyltransferase YP_007039198.1 Glycosyltransferase YP_007039199.1 ADP-heptose:LPS heptosyltransferase YP_007039203.1 Predicted glycosyltransferases YP_007039212.1 predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007039215.1 Glycosyltransferase YP_007039222.1 Phytoene dehydrogenase and related proteins YP_007039223.1 Geranylgeranyl pyrophosphate synthase YP_007039224.1 Phytoene/squalene synthetase YP_007039225.1 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit YP_007039226.1 Uncharacterized conserved protein YP_007039227.1 Methylase involved in ubiquinone/menaquinone biosynthesis YP_007039250.1 Threonine dehydrogenase and related Zn-dependent dehydrogenases YP_007039251.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007039252.1 Cytochrome P450 YP_007039253.1 3-oxoacyl-[acyl-carrier-protein] synthase III YP_007039254.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007039256.1 Cytochrome P450 YP_007039260.1 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase YP_007039261.1 Fructose-2,6-bisphosphatase YP_007039262.1 Anaerobic dehydrogenases, typically selenocysteine-containing YP_007039263.1 Anaerobic dehydrogenases, typically selenocysteine-containing YP_007039264.1 Sterol desaturase YP_007039265.1 AraC-type DNA-binding domain-containing proteins YP_007039266.1 Transcriptional regulator YP_007039267.1 ABC-type multidrug transport system, ATPase and permease components YP_007039268.1 Beta-lactamase class C and other penicillin binding proteins YP_007039270.1 Lysine 2,3-aminomutase YP_007039271.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039272.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039273.1 Lysine/ornithine N-monooxygenase YP_007039275.1 Mannose-6-phosphate isomerase YP_007039276.1 Glycine/D-amino acid oxidases (deaminating) YP_007039277.1 Na+-driven multidrug efflux pump YP_007039278.1 Predicted acyl-CoA transferases/carnitine dehydratase YP_007039279.1 Glycine/D-amino acid oxidases (deaminating) YP_007039280.1 Uncharacterized Fe-S protein YP_007039289.1 Not known, probably involved in the catabolism of octane and guaiacol. It displays a weak activity in the O-dealkylation of 7-ethoxycoumarin YP_007039349.1 ABC-type sugar transport systems, permease components YP_007039350.1 ABC-type sugar transport system YP_007039363.1 Carboxylesterase type B YP_007039394.1 Fucose permease YP_007039395.1 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases YP_007039396.1 Predicted phosphatase/phosphohexomutase YP_007039397.1 Pentose-5-phosphate-3-epimerase YP_007039398.1 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis YP_007039399.1 NADPH:quinone reductase and related Zn-dependent oxidoreductases YP_007039400.1 Threonine dehydrogenase and related Zn-dependent dehydrogenases YP_007039401.1 3-dehydroquinate synthetase YP_007039402.1 Transcriptional regulator/sugar kinase YP_007039403.1 6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase YP_007039404.1 Transcriptional regulator/sugar kinase YP_007039405.1 ADP-ribose pyrophosphatase YP_007039408.1 Transcriptional regulator YP_007039409.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007039410.1 Transcriptional regulator YP_007039411.1 Putative translation initiation inhibitor, yjgF family YP_007039412.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007039413.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007039414.1 Predicted deacylase YP_007039415.1 ABC-type dipeptide transport system,periplasmic component YP_007039416.1 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_007039417.1 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components YP_007039418.1 ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_007039419.1 Aspartate/tyrosine/aromatic aminotransferase YP_007039420.1 Lactate dehydrogenase and related dehydrogenases YP_007039422.1 Transcriptional regulators YP_007039425.1 Predicted Zn-dependent proteases and their inactivated homologs YP_007039426.1 Predicted Zn-dependent proteases and their inactivated homologs YP_007039427.1 Predicted dehydrogenases and related proteins YP_007039430.1 Threonine dehydrogenase and related Zn-dependent dehydrogenases YP_007039431.1 Predicted integral membrane protein YP_007039432.1 ABC-type bacteriocin/lantibiotic exporters,contain an N-terminal double-glycine peptidase domain YP_007039434.1 ABC-type bacteriocin/lantibiotic exporters,contain an N-terminal double-glycine peptidase domain YP_007039435.1 membrane-fusion protein YP_007039439.1 Uncharacterized conserved protein YP_007039442.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039443.1 FOG: PAS/PAC domain YP_007039445.1 Cytochrome P450 YP_007039446.1 Cytochrome P450 YP_007039447.1 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases YP_007039452.1 Uncharacterized conserved protein YP_007039456.1 Uncharacterized conserved protein YP_007039457.1 Response regulator with putative antiterminator output domain YP_007039460.1 Heme/copper-type cytochrome/quinol oxidases,subunit 1 YP_007039461.1 Predicted Zn-dependent hydrolases of the beta-lactamase fold YP_007039462.1 Mn2+ and Fe2+ transporters of the NRAMP family YP_007039464.1 DNA-binding transcriptional activator of the SARP family YP_007039466.1 Uncharacterized protein conserved in bacteria YP_007039468.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases YP_007039469.1 NADPH:quinone reductase and related Zn-dependent oxidoreductases YP_007039470.1 Imidazoleglycerol-phosphate synthase YP_007039471.1 Predicted NAD/FAD-binding protein YP_007039472.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039475.1 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) YP_007039520.1 ADC can be found in two forms: biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins YP_007039523.1 Subtilisin-like serine proteases YP_007039525.1 ABC-type multidrug transport system, ATPase and permease components YP_007039526.1 Asparagine synthase (glutamine-hydrolyzing) YP_007039530.1 Transcriptional regulators YP_007039531.1 Cytosine deaminase and related metal-dependent hydrolases YP_007039532.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007039536.1 Predicted metal-dependent hydrolase with the TIM-barrel fold YP_007039538.1 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family YP_007039541.1 ABC-type multidrug transport system, permease component YP_007039542.1 ATPase components of various ABC-type transport systems, contain duplicated ATPase YP_007039544.1 Cytochrome P450 YP_007039545.1 Nitroreductase YP_007039549.1 Nitroreductase YP_007039550.1 Uncharacterized conserved protein YP_007039557.1 Predicted transcriptional regulator YP_007039558.1 Uncharacterized protein conserved in bacteria YP_007039559.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007039560.1 Transcriptional regulator YP_007039561.1 Uncharacterized protein conserved in bacteria YP_007039562.1 Transcriptional regulators YP_007039572.1 FOG: TPR repeat YP_007039583.1 Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism YP_007039584.1 Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism. CutR suppresses a defective melC1 gene,encoding a putative copper-transfer gene, probably by altering copper metabolism YP_007039594.1 Predicted ATPase YP_007039601.1 Asparagine synthase (glutamine-hydrolyzing) YP_007039602.1 Transcriptional regulator/sugar kinase YP_007039604.1 Predicted flavoprotein YP_007039605.1 Cytochrome P450 YP_007039607.1 4-aminobutyrate aminotransferase and related aminotransferases YP_007039608.1 SAM-dependent methyltransferases YP_007039610.1 Predicted ester cyclase YP_007039611.1 Uncharacterized NAD(FAD)-dependent dehydrogenases YP_007039612.1 Predicted transcriptional regulators YP_007039613.1 Permeases of the major facilitator superfamily YP_007039614.1 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) YP_007039615.1 Biotin carboxylase YP_007039616.1 Biotin carboxylase YP_007039618.1 3-oxoacyl-(acyl-carrier-protein) synthase YP_007039619.1 3-oxoacyl-(acyl-carrier-protein) synthase YP_007039621.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007039623.1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) YP_007039624.1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) YP_007039625.1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) YP_007039626.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_007039627.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_007039635.1 Site-specific recombinase XerD YP_007039636.1 Permeases of the major facilitator superfamily YP_007039638.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_007039639.1 Acyl-CoA dehydrogenases YP_007039640.1 Acyl-CoA dehydrogenases YP_007039641.1 Predicted thioesterase involved in non-ribosomal peptide biosynthesis YP_007039642.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039643.1 Cytochrome P450 YP_007039645.1 Cytochrome P450 YP_007039646.1 Cytochrome P450 YP_007039647.1 Selenocysteine lyase YP_007039648.1 Predicted flavoprotein involved in K+ transport YP_007039649.1 Thioredoxin reductase YP_007039650.1 Predicted transcriptional regulators YP_007039651.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_007039689.1 Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system YP_007039763.1 Member of the two-component regulatory system devR/devS (dosR/dosS) involved in onset of the dormancy response. When phosphorylated binds the promoter of at least its own and Acr (hspX) gene in response to hypoxia. Activates its own transcription under hypoxic but not aerobic conditions, probably binds as a dimer to tandem binding sites within the devR and hspX promoters. Accepts a phosphate group from devS (dosS) and from dosT YP_007039765.1 FOG: GAF domain YP_007039770.1 FOG: CBS domain YP_007039771.1 Universal stress protein UspA and related nucleotide-binding proteins YP_007039772.1 Acyl-CoA synthetase (NDP forming) YP_007039773.1 Universal stress protein UspA and related nucleotide-binding proteins YP_007039774.1 Universal stress protein UspA and related nucleotide-binding proteins YP_007039777.1 Predicted ATP-dependent endonuclease of the OLD family YP_007039778.1 FOG: Transposase and inactivated derivatives YP_007039779.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_007039783.1 Lantibiotic modifying enzyme YP_007039785.1 Integrase YP_007039787.1 Integrase YP_007039788.1 Integrase YP_007039790.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039791.1 Polyketide synthase modules and related proteins YP_007039792.1 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases YP_007039793.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039796.1 Translation elongation factor EF-1alpha (GTPase) YP_007039797.1 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes YP_007039798.1 Permeases of the major facilitator superfamily YP_007039799.1 Predicted aminopeptidases YP_007039800.1 Acetylglutamate kinase YP_007039801.1 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases YP_007039802.1 Acetylglutamate semialdehyde dehydrogenase YP_007039805.1 Deoxyxylulose-5-phosphate synthase YP_007039807.1 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis YP_007039808.1 Cytochrome P450 YP_007039809.1 Acyl-CoA dehydrogenases YP_007039810.1 Acyl-CoA dehydrogenases YP_007039811.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039814.1 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases YP_007039815.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039817.1 Non-ribosomal peptide synthetase modules and related proteins YP_007039818.1 Predicted enzyme related to lactoylglutathione lyase YP_007039821.1 Transposase and inactivated derivatives YP_007039916.1 dTDP-D-glucose 4,6-dehydratase YP_007039972.1 A leucine-specific metalloprotease that plays a role in controlling the amount of leupeptin during colony development. Degrades leupeptin into three components,acetyl-leucine, leucine and argininal YP_007039982.1 Probable taurine catabolism dioxygenase YP_007039988.1 Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA YP_007039992.1 Sortase and related acyltransferases YP_007039993.1 AraC-type DNA-binding domain-containing proteins YP_007039996.1 Aromatic ring hydroxylase YP_007039997.1 dTDP-glucose pyrophosphorylase YP_007039998.1 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II YP_007039999.1 Histidine ammonia-lyase YP_007040000.1 Methylase involved in ubiquinone/menaquinone biosynthesis YP_007040002.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040003.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040004.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040005.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040006.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040007.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040008.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040009.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040010.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040011.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040012.1 Nucleoside-diphosphate-sugar epimerases YP_007040013.1 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) YP_007040014.1 Predicted membrane protein YP_007040015.1 Uncharacterized conserved protein YP_007040018.1 Threonine synthase YP_007040021.1 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis YP_007040023.1 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes YP_007040024.1 Predicted dehydrogenases and related proteins YP_007040025.1 Predicted methyltransferasee (contains TPR repeat) YP_007040026.1 Adenylylsulfate kinase and related kinases YP_007040027.1 Protein related to penicillin acylase YP_007040028.1 Predicted membrane protein YP_007040029.1 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_007040030.1 Predicted integral membrane protein YP_007040075.1 Glycosyltransferase YP_007040078.1 membrane protein involved in the export of O-antigen and teichoic acid YP_007040079.1 Glycosyltransferase YP_007040080.1 Glycosyltransferase YP_007040083.1 Glycosyltransferases involved in cell wall biogenesis YP_007040084.1 Protoporphyrinogen oxidase YP_007040091.1 Responsible for tylosin resistance, and is proposed to be a subunit of a multicomponent export system for the energy- dependent efflux of tylosin YP_007040101.1 Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon YP_007040127.1 Lignostilbene-alpha,beta-dioxygenase YP_007040147.1 Predicted drug exporters of the RND superfamily YP_007040148.1 Transcriptional regulators YP_007040149.1 Transcriptional regulator YP_007040152.1 Transcriptional regulators YP_007040156.1 Beta-lactamase class C and other penicillin binding proteins YP_007040157.1 Protein-tyrosine-phosphatase YP_007040158.1 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) YP_007040159.1 Protein-tyrosine-phosphatase YP_007040160.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040161.1 H+/gluconate symporter and related permeases YP_007040163.1 Transcriptional regulators YP_007040164.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040165.1 Subtilisin-like serine proteases YP_007040166.1 Predicted transcriptional regulators YP_007040167.1 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_007040168.1 Putative translation factor (SUA5) YP_007040171.1 DNA-binding transcriptional activator of the SARP family YP_007040173.1 Exochitinase that generates exclusively chitobiose from chitotetraose, chitohexaose, and colloidal high-molecular mass chitin YP_007040195.1 Involved in glutamate biosynthesis and plays a major role in the primary ammonium ions assimilation in seedling roots. May be involved in the reutilization of glutamine in developing organs. Plays a role in the development of tillers YP_007040204.1 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_007040205.1 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases YP_007040206.1 Geranylgeranyl pyrophosphate synthase YP_007040207.1 Penicillin tolerance protein YP_007040208.1 Deoxyxylulose-5-phosphate synthase YP_007040209.1 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis YP_007040219.1 Glycosyltransferases involved in cell wall biogenesis YP_007040220.1 This enzyme catalyzes carboxypeptidation and transpeptidation reactions involved in bacterial cell wall metabolism. It effectively catalyzes the transfer of the N-alpha, N-epsilon-diacetyl-L-lysyl-D-alanyl electrophilic group of the standard tripeptide substrate N-alpha,N-epsilon-diacetyl-L-lysyl- D-alanyl-D-alanine to water. It also performs a weak beta- lactamase activity,hydrolyzing penicillin into penicilloate at a very low rate YP_007040233.1 Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for energy coupling to the transport system YP_007040247.1 Plays an essential role in the utilization of numerous aromatic and hydroaromatic compounds via the beta-ketoadipate pathway YP_007040273.1 Subtilisin-like serine proteases YP_007040288.1 NAD-dependent aldehyde dehydrogenases YP_007040305.1 Catalyzes the conversion of maltooligosaccharide into the non-reducing saccharide,maltooligosyl trehalose (alpha- maltooligosyl alpha-D-glucoside) by intramolecular transglycosylation YP_007040316.1 membrane carboxypeptidase (penicillin-binding protein) YP_007040329.1 Cell division protein FtsI/penicillin-binding protein 2 YP_007040341.1 Subtilisin-like serine proteases YP_007040342.1 dGTP triphosphohydrolase YP_007040343.1 Predicted integral membrane sensor domain protein YP_007040344.1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases YP_007040345.1 FOG: EAL domain YP_007040346.1 Uncharacterized conserved protein YP_007040349.1 Predicted metal-sulfur cluster biosynthetic enzyme YP_007040350.1 NifU-like protein, involved in Fe-S cluster formation YP_007040351.1 Selenocysteine lyase YP_007040352.1 ABC-type transport system involved in Fe-S cluster assembly, ATPase component YP_007040353.1 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit YP_007040354.1 ABC-type transport system involved in Fe-S cluster assembly, permease component YP_007040355.1 ABC-type transport system involved in Fe-S cluster assembly, permease component YP_007040359.1 Glycosyltransferase YP_007040386.1 Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_007040414.1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate YP_007040417.1 ATP-dependent transcriptional regulator YP_007040419.1 May act as RNA methyltransferase YP_007040428.1 DNA-directed RNA polymerase, subunit K/omega YP_007040446.1 3-dehydroquinate synthetase YP_007040496.1 May be involved in active puromycin efflux energized by a proton-dependent electrochemical gradient. In addition, it could be implicated in secreting N-acetylpuromycin, the last intermediate of the puromycin biosynthesis pathway, to the environment YP_007040505.1 Catalyzes the cyclization of 2-amino-4,5-dihydroxy-6- one-heptanoic acid-7-phosphate to yield 3-amino-4-hydroxybenzoic acid (3,4-AHBA) YP_007040506.1 Catalyzes aldol condensation between L-aspartate-4- semialdehyde (ASA) and dihydroxyacetone phosphate (DHAP), to form 2-amino-4,5-dihydroxy-6-one-heptanoic acid-7-phosphate YP_007040509.1 FOG: TPR repeat YP_007040524.1 Part of the ABC transporter complex TcyABC involved in L-cystine import. Responsible for energy coupling to the transport system (Probable) YP_007040528.1 Catalyzes the reduction of N-ethylmaleimide (NEM) to N- ethylsuccinimide YP_007040563.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) YP_007040567.1 Short-chain alcohol dehydrogenase of unknown specificity YP_007040576.1 Responsible for the C-12 hydroxylation of the macrolactone ring of erythromycin YP_007040577.1 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP YP_007040602.1 DNA-directed RNA polymerase specialized sigma subunit YP_007040648.1 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) YP_007040678.1 May play a role in septum formation YP_007040681.1 May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer YP_007040708.1 Ornithine/acetylornithine aminotransferase YP_007040725.1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins YP_007040756.1 Dihydrodipicolinate synthase/N-acetylneuraminate lyase YP_007040777.1 Predicted integral membrane protein YP_007040815.1 In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity YP_007040818.1 Component of the high-affinity branched-chain amino acid transport system YP_007040819.1 Component of the high affinity leucine,isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids YP_007040823.1 Member of the two-component regulatory system pdtaR/pdtaS YP_007040828.1 Transcriptional regulator YP_007040832.1 Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive YP_007040840.1 Transcriptional regulator YP_007040842.1 Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase YP_007040882.1 Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine YP_007040895.1 Interconversion of serine and glycine YP_007040911.1 Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose YP_007040917.1 Hydrolyzes chitin oligosaccharides; (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5,6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin, glucosamine oligosaccharides,glycoproteins and glycopeptides containing (GlcNAc)2 YP_007040930.1 Glutamate decarboxylase and related PLP-dependent proteins YP_007040931.1 Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known YP_007040934.1 Uncharacterized conserved protein YP_007040935.1 DNA or RNA helicases of superfamily II YP_007040937.1 Endonuclease I YP_007040938.1 Glycosyl transferases, related to UDP-glucuronosyltransferase YP_007040939.1 Putative translation initiation inhibitor, yjgF family YP_007040940.1 Predicted transcriptional regulators YP_007040941.1 NADPH-dependent glutamate synthase beta chain and related oxidoreductases YP_007040942.1 Glutamate synthase domain 1 YP_007040943.1 Na+/H+-dicarboxylate symporters YP_007040950.1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate YP_007040965.1 The FAS-operon encodes genes involved in cytokinin production and in host plant fasciation (leafy gall) YP_007040966.1 Plays a role in electron transfer. The fas operon encodes genes involved in cytokinin production and in host plant fasciation (leafy gall) YP_007040971.1 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase YP_007040979.1 Catalyzes the oxidation of L-aspartate to iminoaspartate YP_007040991.1 Not known, probably involved in the catabolism of octane and guaiacol. It displays a weak activity in the O-dealkylation of 7-ethoxycoumarin YP_007041017.1 UDP-N-acetylmuramate-alanine ligase YP_007041018.1 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase YP_007041019.1 Bacterial cell division membrane protein YP_007041025.1 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase YP_007041028.1 Cell division protein FtsI/penicillin-binding protein 2 YP_007041048.1 May function as a proton-driven pyrimidine uptake system YP_007041062.1 Dihydrodipicolinate synthase/N-acetylneuraminate lyase YP_007041101.1 uncharacterized conserved protein YP_007041110.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_007041129.1 ATP:corrinoid adenosyltransferase YP_007041148.1 Catalyzes the NAD(P)H-dependent reduction of mycothione (the oxidized disulfide form of mycothiol) to mycothiol YP_007041165.1 Methionine aminopeptidase YP_007041166.1 Predicted nucleic acid-binding protein,contains PIN domain YP_007041168.1 Cell division protein FtsI/penicillin-binding protein 2 YP_007041169.1 Predicted acetyltransferase YP_007041170.1 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis YP_007041171.1 Predicted membrane-associated Zn-dependent proteases 1 YP_007041192.1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome YP_007041195.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released YP_007041219.1 Involved in the uptake of ammonia (Probable) YP_007041257.1 Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon YP_007041269.1 8 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) YP_007041271.1 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic function in B.subtilis as it is necessary for growth on glucose, but is not required for sporulation YP_007041296.1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate YP_007041297.1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate YP_007041366.1 Glycosyltransferase YP_007041380.1 Glucan phosphorylase YP_007041382.1 Could be involved in glycogen catabolism YP_007041383.1 Catalyzes the conversion of maltose into alpha,alpha- trehalose by transglucosylation YP_007041403.1 Phosphomannose isomerase YP_007041409.1 Member of the two-component regulatory system devR/devS (dosR/dosS) involved in onset of the dormancy response. When phosphorylated binds the promoter of at least its own and Acr (hspX) gene in response to hypoxia. Activates its own transcription under hypoxic but not aerobic conditions, probably binds as a dimer to tandem binding sites within the devR and hspX promoters. Accepts a phosphate group from devS (dosS) and from dosT YP_007041429.1 Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. Binds covalently dihydroxyacetone in hemiaminal linkage. Acts also as a corepressor of dhaR by binding to its sensor domain, in the absence of dihydroxyacetone YP_007041444.1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_007041446.1 Required for the assimilation of methanol and ethanol YP_007041463.1 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase YP_007041498.1 Necessary for activation of the czc determinant; may function as a membrane-bound sensor protein or as a metal ion transporter YP_007041501.1 Transposase YP_007041505.1 Mg(2+)-activated ribonuclease which hydrolyzes RNA apparently nonspecifically into oligonucleotides with 5'-terminal phosphate YP_007041524.1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase YP_007041525.1 1.5.1.10 : Glycine YP_007041537.1 predicted transcriptional regulators YP_007041575.1 ABC-type amino acid transport system, permease component YP_007041578.1 ABC-type amino acid transport/signal transduction systems YP_007041585.1 Cyclopropane fatty acid synthase YP_007041586.1 FAD/FMN-containing dehydrogenases YP_007041597.1 Enzyme is most active on medium length p-nitrophenyl esters (with C8 to C12 acyl chains) YP_007041608.1 Transforms O-acetylhomoserine into homocysteine YP_007041619.1 May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer YP_007041648.1 In addition to the NAD-dependent oxidative decarboxylation of L-malate, the enzyme catalyzes the decarboxylation of oxaloacetate YP_007041649.1 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes YP_007041671.1 Histone acetyltransferase HPA2 YP_007041677.1 Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR YP_007041680.1 uncharacterized conserved protein YP_007041697.1 Predicted amidophosphoribosyltransferases YP_007041700.1 Member of the two-component regulatory system mtrA/mtrB YP_007041711.1 Phosphomannose isomerase YP_007041714.1 Phosphomannomutase YP_007041717.1 Predicted glycosyltransferases YP_007041720.1 Uncharacterized conserved protein YP_007041723.1 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) YP_007041725.1 Predicted glycosyltransferases YP_007041727.1 Glycosyltransferase YP_007041728.1 Glycosyltransferase YP_007041729.1 Predicted glycosyltransferases YP_007041731.1 membrane carboxypeptidase (penicillin-binding protein) YP_007041732.1 Glycosyltransferase YP_007041737.1 dTDP-D-glucose 4,6-dehydratase YP_007041756.1 Catalyzes the dephosphorylation of histidinol-phosphate to histidinol, the direct precursor of histidine (Probable) YP_007041762.1 Involved in the catabolism of branched amino acids such as leucine (Probable) YP_007041782.1 May contribute to virulence by increasing resistance to reactive oxygen intermediates. It can reduce 2,6-dimethyl-1,4- benzoquinone (DMBQ),5-hydroxy-1,4-naphthaquinone (5-HNQ) and menadione. NAD(P)H is the physiological reductant rather than NADH YP_007041783.1 Key enzyme in the regulation of glycerol uptake and metabolism YP_007041790.1 Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. This conversion most likely represents an important source of building blocks for polyketide antibiotic biosynthesis. It is unable to catalyze the conversion of isobutyryl-CoA into N-butyryl-CoA YP_007041791.1 Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. This conversion most likely represents an important source of building blocks for polyketide antibiotic biosynthesis. It is unable to catalyze the conversion of isobutyryl-CoA into N-butyryl-CoA YP_007041793.1 Purine nucleoside phosphorylase YP_007041856.1 Cytochrome P450 YP_007041865.1 Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases YP_007041874.1 Essential for pSAM2 replication YP_007041908.1 Nucleotidyltransferase/DNA polymerase involved in DNA repair YP_007041942.1 2-polyprenyl-6-methoxyphenol hydroxylase YP_007041944.1 Catalyzes the oxidation and isomerization of cholesterol to cholestenone (4-cholesten-3-one), which is an initial step in the cholesterol degradation process. Required for virulence YP_007041959.1 predicted ATPase YP_007041975.1 Phosphomannomutase YP_007041993.1 Glycosyltransferase YP_007041998.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_007042006.1 Removes the amino-terminal methionine from nascent proteins YP_007042031.1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis YP_007042042.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_007042043.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_007042046.1 ABC-type transport system involved in resistance to organic solvents YP_007042047.1 ABC-type transport system involved in resistance to organic solvents YP_007042048.1 ABC-type transport system involved in resistance to organic solvents YP_007042049.1 ABC-type transport system involved in resistance to organic solvents YP_007042054.1 Not known, could be involved in the transport of ribonucleotides YP_007042075.1 dTDP-glucose pyrophosphorylase YP_007042101.1 Essential for pSAM2 replication YP_007042111.1 Geranylgeranyl pyrophosphate synthase YP_007042128.1 Glycosyltransferase YP_007042129.1 Glycosyltransferase YP_007042132.1 May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation YP_007042136.1 May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation YP_007042143.1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) YP_007042144.1 Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl- CoA (OSB-CoA). May be involved in the biosynthesis of menaquinone YP_007042174.1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps YP_007042196.1 Probably forms part of a two-component regulatory system regX3/senX3 YP_007042197.1 Part of the two-component regulatory system senX3/regX3. Phosphorylates regX3 under conditions of phosphate limitation. Probably does not itself sense phosphate concentrations, which may be relayed to senX3 by the pstSCAB phosphate transporter system YP_007042208.1 Glycosyltransferase YP_007042287.1 Activates the transcription of the glnA gene YP_007042292.1 May be a sulfotransferase involved in the formation of thiosulfate YP_007042294.1 May play a role in the intracellular transport of hydrophobic ligands (Potential) YP_007042317.1 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog YP_007042320.1 Glutamine phosphoribosylpyrophosphate amidotransferase YP_007042328.1 PPE-repeat proteins YP_007042331.1 Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration. Has no beta-mannosidase activity YP_007042340.1 This enzyme has both lysozyme (acetylmuramidase) and diacetylmuramidase activities YP_007042352.1 Part of the binding-protein-dependent transport system for glutamine. Probably responsible for energy coupling to the transport system YP_007042361.1 Stereospecifically catalyzes the interconversion of L- allo-threonine and glycine YP_007042382.1 Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane YP_007042383.1 Adenylosuccinate synthase YP_007042477.1 Part of the binding-protein-dependent transport system for glutamine. Probably responsible for energy coupling to the transport system YP_007042524.1 Nitric oxide synthase, oxygenase domain YP_007042532.1 Acts to efflux copper or a copper complex. It is possible that yfmO could contribute to copper resistance YP_007042538.1 membrane carboxypeptidase (penicillin-binding protein) YP_007042539.1 Predicted integral membrane protein YP_007042547.1 Predicted integral membrane protein YP_007042561.1 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP YP_007042581.1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA YP_007042583.1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) YP_007042588.1 Involved in the high-affinity D-ribose membrane transport system and also serves as the primary chemoreceptor for chemotaxis YP_007042589.1 Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane