-- dump date   	20111121_014509
-- class       	Genbank::CDS
-- table       	cds_function
-- id	function
YP_003566124.1	Mobile and extrachromosomal element functions: Plasmid functions
YP_003566148.1	Single-stranded-DNA-specific exonuclease
YP_003566152.1	Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase.
YP_003566155.1	The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence.
YP_003566157.1	Subunit R is required for both nuclease and ATPase activities, but not for modification
YP_003566159.1	The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence.
YP_003566160.1	Methylation of specific adenine residues; required for both restriction and modification activities
YP_003566162.1	involved in plasmid maintenance and replication
YP_003566170.1	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.
YP_003569736.1	Involved in plasmid partition.
YP_003569739.1	Involved in the transposition of the insertion sequence
YP_003569751.1	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.
YP_003569754.1	Involved in the tonB-independent uptake of proteins
YP_003569875.1	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
YP_003569876.1	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, It slides freely (bidirectional and ATP-independent) along duplex DNA.
YP_003569888.1	The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding.
YP_003569889.1	nvolved in the transcription termination process.
YP_003569890.1	Plays a key role in signaling protein misfolding via the cpxR/CPXA transducing system. It also modulates the phosphorylated status of many phosphoproteins in E.coli, some of which acting as major chaperones. Has been shown, in vitro, to act on Ser, Thr and Tyr-phosphorylated substrates.
YP_003569893.1	Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of lolA.
YP_003569894.1	Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3- sulfolactate (PSL).
YP_003569900.1	Catalyzes two steps in the biosynthesis of coenzyme A.
YP_003569902.1	Essential for recycling GMP and indirectly, cGMP.
YP_003569904.1	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
YP_003569905.1	Catalyzes the phosphorylation of UMP to UDP.
YP_003569906.1	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
YP_003569912.1	Not known, probably involved in fatty acid or phospholipid synthesis.
YP_003569913.1	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
YP_003569914.1	It is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl- carrier protein.
YP_003569916.1	fatty acid biosynthesis.
YP_003569926.1	equired for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex.
YP_003569927.1	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2- thiouridine, which is found in the wobble position of some tRNAs.
YP_003569932.1	Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs.
YP_003569933.1	Probable S-adenosyl-L-methionine dependent methyltransferase specific for a sterol and/or lipid substrate.
YP_003569935.1	Necessary for strand-specific repair. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognized by TRCF which releases RNAP and the truncated transcript; the TCRF may replace RNAP at the lesion site and then recruit the uvrA/B/C repair system.
YP_003569941.1	The recF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single- stranded, linear DNA. It also seems to bind ATP.
YP_003569952.1	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
YP_003569955.1	Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).
YP_003569956.1	The enzyme catalyses the first step in the pentose pathway, i.e. the conversion of glucose-6- phosphate to gluconolactone 6-phosphate in the presence of NADP, producing NADPH.
YP_003569973.1	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
YP_003569985.1	Involved in export of lead, cadmium, zinc and mercury.
YP_003569992.1	Not known
YP_003570005.1	Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism.
YP_003570026.1	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
YP_003570027.1	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
YP_003570029.1	This protein is part of an active transport system that transports exogenous cyanate into Escherichia coli cells.
YP_003570038.1	Responsible for detecting glucose and alpha- methylglucoside.
YP_003570040.1	Required for resistance to DNA-damaging agents.
YP_003570044.1	Respond to changes in the concentration of attractants and repellents in the environment, and transduce a signal from the outside to the inside of the cell
YP_003570047.1	Responsible for energy coupling to the transport system
YP_003570058.1	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from ccdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached
YP_003570061.1	Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
YP_003570078.1	Responsible for energy coupling to the transport system
YP_003570088.1	ATP + L-aspartate + L-glutamine + H2O = AMP + diphosphate + L-asparagine + L-glutamate
YP_003570097.1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing in the extracytoplasmic compartment
YP_003570098.1	yuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids
YP_003570118.1	Required for the extracellular polysaccharide colanic acid synthesis
YP_003570120.1	Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism
YP_003570141.1	Involved in cell wall biogenesis
YP_003570144.1	Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-glutamine route).
YP_003570149.1	Catalyse the conversion of aspartate to asparagine.
YP_003570170.1	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
YP_003570171.1	act as non-specific phosphomonoesterases to hydrolyse phosphate esters, optimally at high pH.
YP_003570174.1	Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism
YP_003570175.1	Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism.
YP_003570180.1	This protein is a serine beta-lactamase with a substrate specificity for cephalosporins catalyses the opening and hydrolysis of the beta-lactam ring of beta- lactam antibiotics such as penicillins and cephalosporins.
YP_003570186.1	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins
YP_003570188.1	Plays a role in electron transfer. The FAS- operon encodes genes involved in cytokinin production and in host plant fasciation
YP_003570190.1	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
YP_003570202.1	Component of the thioredoxin-thioredoxin reductase system.
YP_003570211.1	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates.
YP_003570217.1	Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched duplex DNA (Y- DNA)
YP_003570223.1	catalyzes the reversible transfer of a two- carbon ketol unit from xylulose 5-phosphate to an aldose receptor to form sedoheptulose 7-phosphate and glyceraldehyde 3- phosphate.
YP_003570224.1	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YP_003570230.1	Synthesizes alpha-1,4-glucan chains using ADP- glucose
YP_003570239.1	Biosynthesis and degradation of murein sacculus and peptidoglycan
YP_003570246.1	DNA helicase
YP_003570250.1	Provides the precursors necessary for DNA synthesis.
YP_003570253.1	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Has been shown to bind to the 14 bp palindromic sequence 5'-CGAACNNNNGTTCG-3'. In the presence of single- stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair.
YP_003570254.1	Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis.
YP_003570257.1	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide
YP_003570259.1	Involved in copper processing and transport; in the assembly of the copper chromophores of nitrous oxide reductase.
YP_003570266.1	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1
YP_003570267.1	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
YP_003570269.1	May regulate the transcription
YP_003570275.1	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c or a quinol are transferred to the bimetallic center formed by a high- spin heme and copper B.
YP_003570280.1	Mediates zinc uptake. May also transport other divalent cations
YP_003570281.1	Involved in protection of chromosomal DNA from damage under nutrient-limited and oxidative stress conditions.
YP_003570282.1	Has a low cation transport activity for cobalt, it is essential for the expression of cobalt, zinc, and cadmium resistance.
YP_003570288.1	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by cheR
YP_003570289.1	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
YP_003570292.1	Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP
YP_003570298.1	Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation.
YP_003570300.1	The first enzyme in the salvage pathway of NAD biosynthesis from nicontinate
YP_003570314.1	catalyses the interchange of 5- formyltetrahydrofolate (5-FTHF) to 5-10- methenyltetrahydrofolate
YP_003570318.1	# Hydrolysis of terminal, non-reducing N-acetyl- beta-D-glucosamine residues in chitobiose and higher analogs, and in glycoproteins.
YP_003570319.1	Transcriptional repressor for the ribose rbsDACBK operon
YP_003570323.1	Catalyzes the phosphorylation of N-acetyl-D- glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
YP_003570324.1	# Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
YP_003570330.1	# May be involved in vascular wall and kidney homeostasis.
YP_003570331.1	This enzyme can act in threonine catabolism.
YP_003570334.1	Glutamine synthetase ( 6.3.1.2 ) (GS) [ 1 ] plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine.
YP_003570336.1	hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non- carbohydrate moiety.
YP_003570340.1	# Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity. In lung tissue, it may terminate or significantly reduce the leukotriene induced signal for bronchospasm.
YP_003570343.1	NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain
YP_003570344.1	NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.
YP_003570345.1	Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Component of the iron- sulfur (IP) fragment of the enzyme
YP_003570346.1	# Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Component of the flavoprotein-sulfur (FP) fragment of the enzyme.
YP_003570349.1	NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YP_003570354.1	an use both glutamine or ammonia as a nitrogen source
YP_003570355.1	# This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
YP_003570366.1	# Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism.
YP_003570369.1	# Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate.
YP_003570370.1	Provides the sole de novo source of dTMP for DNA biosynthesis
YP_003570373.1	# Reduction of activated sulfate into sulfite.
YP_003570377.1	Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAO-A preferentially oxidizes biogenic amines such as 5- hydroxytryptamine (5-HT), norepinephrine and epinephrine
YP_003570381.1	# Involved in a multicomponent binding-protein- dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system.
YP_003570393.1	probably involved in phosphate transport and/or metabolism
YP_003570398.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_003570403.1	# Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde.
YP_003570405.1	Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accomodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YP_003570407.1	The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of ruvB
YP_003570416.1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon interaction with the dnaJ-bound protein, dnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from dnaK; ATP binding to dnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between dnaJ, dnaK and grpE are required for fully efficient folding. Also involved, together with dnaK and grpE, in the DNA replication of plasmids through activation of initiation proteins
YP_003570417.1	Component of the acetyl coenzyme A carboxylase (ACC) complex
YP_003570426.1	Defense mechanisms
YP_003570429.1	# Probable outer membrane component of the sepABC efflux pump with unknown specificity.
YP_003570431.1	# PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
YP_003570432.1	Transforms O-acetylhomoserine into homocysteine
YP_003570433.1	catalyses the first step unique to methionine biosynthesis, converting L-homoserine to O-acetyl-L- homoserine using acetyl-CoA as an acetyl group donor
YP_003570434.1	Catalyzes the phosphorylation of aspartate
YP_003570435.1	Catalyses the first and third steps of methionine and threonine biosynthesis
YP_003570439.1	Succinate + acceptor = fumarate + reduced acceptor.
YP_003570440.1	Succinate + acceptor = fumarate + reduced acceptor.
YP_003570441.1	Putative hydrophobic component of the succinate dehydrogenase complex
YP_003570442.1	The exact function of the plasmid-encoded citrate synthase is not clear, it could help nodulation by allowing the bacteria to use citrate as a chelator of iron and calcium.
YP_003570443.1	Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process.
YP_003570447.1	Catalyzes a trans-dehydration via an enolate intermediate
YP_003570451.1	May donate electrons to ubiquinone.
YP_003570453.1	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.
YP_003570456.1	Dephosphorylates etk
YP_003570463.1	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates.
YP_003570464.1	Catalyses the conversion of D-ribose 5- phosphate to D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway.
YP_003570466.1	Members of this family are helicases that catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA.
YP_003570473.1	Rhomboid-type serine protease that catalyzes intramembrane proteolysis
YP_003570477.1	This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair
YP_003570485.1	BirA acts both as a biotin-operon repressor and as the enzyme that synthesizes the corepressor, acetyl- CoA:carbon-dioxide ligase.
YP_003570487.1	enzymes of the inositol phosphate second messenger signalling pathway
YP_003570489.1	Catalyzes the dephosphorylation of 2- phosphoglycolate.
YP_003570494.1	Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present.
YP_003570498.1	The HIT superfamily are conserved as nucleotide- binding proteins and that Hint homologs
YP_003570503.1	Oxidizes PNP and PMP into pyridoxal 5'- phosphate (PLP)
YP_003570505.1	# Oxidizes proline to glutamate for use as a carbon and nitrogen source, and also functions as a transcriptional repressor of its own gene.
YP_003570509.1	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen
YP_003570510.1	# Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'- CTGTATATATATACAG-3'. In the presence of single-stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).
YP_003570512.1	Exhibits a S-adenosyl-dependent methyltransferase activity
YP_003570515.1	Cell wall formation. Diaminopimelic acid adding enzyme
YP_003570516.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.
YP_003570517.1	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl- L-alanine (UMA)
YP_003570519.1	Cell wall formation
YP_003570520.1	This protein may be involved in septum formation.
YP_003570521.1	This protein may be involved in septum formation
YP_003570522.1	# This protein is essential to the cell- division process. It seems to assemble into a dynamic ring on the inner surface of the cytoplasmic membrane at the place where division will occur, and the formation of the ring is the signal for septation to begin. Binds to and hydrolyzes GTP (By similarity).
YP_003570531.1	# Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group C2 O antigen.
YP_003570532.1	catalyse the de-phosphorylation of trehalose-6- phosphate to trehalose and orthophosphate
YP_003570533.1	This enzime catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life.
YP_003570535.1	# Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols.
YP_003570537.1	Provides the D-alanine required for cell wall biosynthesis
YP_003570539.1	# Member of the two-component regulatory system cusS/cusR. Copper ion sensor. Could also be a silver ion sensor. Probably activates cusR by phosphorylation.
YP_003570544.1	ATP + sulfate = diphosphate + adenylyl sulfate.
YP_003570547.1	May be the GTPase, regulating ATP sulfurylase activity
YP_003570554.1	# Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.
YP_003570555.1	is involved in the biosynthesis of dTDP-l- rhamnose, which is an essential component of the bacterial cell wall, converting dTDP-4-keto-6-deoxy-D-glucose to dTDP-4-keto-L-rhamnose
YP_003570567.1	Galactose metabolism; third step.
YP_003570569.1	Aminosugars metabolism
YP_003570572.1	# Produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). Can also use N-acetylmannosamine 6-phosphate and mannose 6- phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
YP_003570573.1	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YP_003570576.1	Together with algJ and algF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid.
YP_003570578.1	Together with algJ and algF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid
YP_003570591.1	Probably involved in the synthesis of sugar components of EPS I, by converting NDP-N-acetyl-D- galactosamine into NDP-N-acetyl-D-galactosaminuronic acid
YP_003570613.1	Required for the transposition of the insertion element
YP_003570624.1	Required for the transposition of the insertion element
YP_003570659.1	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerC binding sites by a short central region, forming the heterotetrameric xerC-xerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex xerD specifically exchanges the bottom DNA strands (By similarity).
YP_003570671.1	Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase
YP_003570694.1	Catalyses the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis
YP_003570697.1	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate
YP_003570702.1	Proteolytically removes the C-terminal three residues of farnesylated proteins
YP_003570706.1	Predicted transcription factor
YP_003570713.1	Involved in the formation of pseudouridine at the anticodon stem and loop of transfer-RNAs Pseudouridine is an isomer of uridine uracil, and id the most abundant modified nucleoside found in all cellular RNAs
YP_003570718.1	Serine biosynthesis
YP_003570720.1	Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
YP_003570721.1	Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports proteins with bound cofactors that require folding prior to export (By similarity).
YP_003570722.1	Adenosine deaminase ( 3.5.4.4 ) catalyzes the hydrolytic deamination of adenosine into inosine and AMP deaminase ( 3.5.4.6 ) catalyzes the hydrolytic deamination of AMP into IMP
YP_003570726.1	Required for resistance to DNA-damaging agents (By similarity).
YP_003570731.1	Converts 2C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E) - butenyl 4-diphosphate (By similarity).
YP_003570738.1	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity).
YP_003570741.1	Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules.
YP_003570754.1	Part of a potassium transport system (By similarity).
YP_003570766.1	Involved in the binding of tRNA to the ribosomes (By similarity).
YP_003570767.1	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (By similarity).
YP_003570768.1	All proteins in this family, for which functions are known, are single-stranded DNA-binding proteins that function in many processes including transcription, repair, replication and recombination.
YP_003570769.1	Histidine degradation; first step
YP_003570770.1	Essential helicase (By similarity).
YP_003570778.1	ATP phosphoribosyltransferase (EC:2.4.2.17) is the enzyme that catalyzes the first step in the biosynthesis of histidine in bacteria, fungi and plants.
YP_003570787.1	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides. It can also degrade 3' or 5' ss regions extending from the termini of duplex DNA molecules and displaced ss regions.
YP_003570793.1	This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds.
YP_003570795.1	Anaerobic transformation of coproporphyrinogen- III into protoporphyrinogen-IX.
YP_003570798.1	Member of the two-component regulatory system lytR/lytS that regulates genes involved in autolysis and cell wall metabolism. Regulates the activity of the cell wall-associated murein hydrolase through regulation of lrgA and lrgB.
YP_003570813.1	Catalyzes the conversion of 7,8- dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
YP_003570814.1	Catalyzes the synthesis of GMP from XMP (By similarity).
YP_003570815.1	Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.
YP_003570816.1	ATPases involved in chromosome partitioning
YP_003570827.1	Interconversion of serine and glycine.
YP_003570829.1	Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports proteins with bound cofactors that require folding prior to export (By similarity).
YP_003570832.1	Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity).
YP_003570836.1	These enzymes phosphorylate glucose using ATP as a donor to give glucose-6-phosphate and ADP.
YP_003570837.1	Required for the cell division process (By similarity).
YP_003570842.1	Synthesizes alpha-1,4-glucan chains using ADP- glucose
YP_003570851.1	May be involved in recombinational repair of damaged DNA (By similarity).
YP_003570852.1	Involved in protein export. Interacts with the secY/secE subunits. SecA has a central role in coupling the hydrolysis of ATP to the transfer of pre-secretory periplasmic and outer membrane proteins across the membrane (By similarity).
YP_003570853.1	Required for resistance to DNA-damaging agents (By similarity).
YP_003570854.1	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerC binding sites by a short central region, forming the heterotetrameric xerC-xerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex xerD specifically exchanges the bottom DNA strands (By similarity).
YP_003570863.1	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) . It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
YP_003570864.1	Generates a proton motive force; it probably catalyzes a fully reversible reaction, thus being able to synthesize pyrophosphate when the proton motive force is sufficient (By similarity).
YP_003570865.1	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity).
YP_003570866.1	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
YP_003570874.1	Methylates ribosomal protein L11 (By similarity).
YP_003570875.1	Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4- benzoquinol (DMQH2) (By similarity).
YP_003570879.1	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity).
YP_003570880.1	Catalyzes a 2-step reaction, involving the ATP- dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production.
YP_003570887.1	Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation
YP_003570897.1	In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium
YP_003570902.1	Catalyzes the formation of the alpha-1,6- glucosidic linkages in glycogen by scission of a 1, 4-alpha- linked oligosaccharide from growing alpha-1, 4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity).
YP_003570903.1	Catalyzes the conversion of maltose into alpha, alpha-trehalose by transglucosylation.
YP_003570911.1	Part of a potassium transport system (By similarity).
YP_003570914.1	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.
YP_003570919.1	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
YP_003570921.1	Catalyzes the reversible isomerization- deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity).
YP_003570928.1	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein tonB (By similarity).
YP_003570939.1	Specifically methylates the ribose of guanosine 2251 in 23S rRNA (By similarity).
YP_003570950.1	This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'- hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity).
YP_003570960.1	This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
YP_003570967.1	This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle during sporulation.
YP_003570972.1	Binds directly to 16S ribosomal RNA (By similarity).
YP_003570977.1	Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity).
YP_003570980.1	This protein seems to be part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) into CF(1) or is implicated in proton conduction.
YP_003570981.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
YP_003570982.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
YP_003570984.1	Exhibits several catalytic activities
YP_003570987.1	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
YP_003570988.1	Cell wall formation (By similarity).
YP_003570995.1	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6- hydroxy-phenol, the fourth step in ubiquinone biosynthesis. Required for the expression of 2'-N- acetyltransferase.
YP_003570997.1	Formation of iron-sulfur complexes and cyanide detoxification. Binds molecular oxygen and sulfur.
YP_003571001.1	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
YP_003571002.1	This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA (By similarity).
YP_003571004.1	biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
YP_003571016.1	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).
YP_003571023.1	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
YP_003571024.1	The carbamoyl-phosphate synthase domain is in the amino terminus of protein. Carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl- phosphate from glutamine or ammonia and bicarbonate. This important enzyme initiates both the urea cycle and the biosynthesis of arginine and/or pyrimidines
YP_003571025.1	Carbamoyl-phosphate synthase (CPSase) catalyzes the ATP-dependent synthesis of carbamyl-phosphate from glutamine () or ammonia () and bicarbonate
YP_003571028.1	This enzyme, CDP-diacylglycerol--serine O- phosphatidyltransferase, is involved in phospholipid biosynthesis catalyzing the reaction CDP-diacylglycerol + L-serine = CMP + L-1-phosphatidylserine.
YP_003571029.1	This entry represents a single-molecule form of phosphoribosylformylglycinamidine synthase, also called FGAM synthase, an enzyme of purine de novo biosynthesis
YP_003571030.1	Involved in the modulation of the specificity of the clpAP-mediated ATP-dependent protein degradation (By similarity).
YP_003571036.1	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis.
YP_003571038.1	Catalyzes the synthesis of GMP from XMP (By similarity).
YP_003571041.1	Catalyzes the synthesis of GMP from XMP (By similarity).
YP_003571046.1	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase (By similarity).
YP_003571048.1	Key enzyme in the regulation of glycerol uptake and metabolism.
YP_003571051.1	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity).
YP_003571058.1	May be a sulfotransferase involved in the formation of thiosulfate (By similarity).
YP_003571076.1	Catalyzes the NAD-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylate to form 1-amino-3-(phosphohydroxy)propan-2- one (3-amino-2-oxopropyl phosphate) (By similarity).
YP_003571103.1	With S4 and S5 plays an important role in translational accuracy (By similarity).
YP_003571104.1	This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.
YP_003571105.1	This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.
YP_003571106.1	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
YP_003571107.1	Involved in the binding of tRNA to the ribosomes (By similarity).
YP_003571109.1	One of the primary rRNA binding proteins, it binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity).
YP_003571110.1	One of the primary rRNA binding proteins, this protein initially binds near the 5' end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
YP_003571111.1	Binds to the 23S rRNA.
YP_003571112.1	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).
YP_003571113.1	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity).
YP_003571114.1	This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
YP_003571115.1	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity).
YP_003571116.1	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity).
YP_003571118.1	Binds specifically to the 5' end of 16S ribosomal RNA. S17 is thought to be involved in the recognition of termination codons (By similarity).
YP_003571119.1	This protein binds directly to 23S ribosomal RNA (By similarity).
YP_003571120.1	One of two assembly inititator proteins, it binds directly to the 5' end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity).
YP_003571121.1	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (By similarity).
YP_003571122.1	Known to be required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity).
YP_003571123.1	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity).
YP_003571124.1	This protein binds directly to 23S ribosomal RNA and is located at the aminoacyl-tRNA binding site of the peptidyltransferase center.
YP_003571125.1	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity).
YP_003571126.1	With S4 and S12 plays an important role in translational accuracy (By similarity).
YP_003571127.1	Binds to the 23S rRNA (By similarity).
YP_003571128.1	Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel.
YP_003571129.1	Removes the amino-terminal methionine from nascent proteins.
YP_003571130.1	No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3.
YP_003571131.1	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites (By similarity).
YP_003571132.1	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity).
YP_003571133.1	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity).
YP_003571134.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YP_003571136.1	In eubacteria ppGpp (guanosine 3'-diphosphate 5- ' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the degradation of ppGpp into GDP. It may also be capable of catalyzing the synthesis of ppGpp (By similarity).
YP_003571137.1	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions (By similarity).
YP_003571138.1	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination.
YP_003571141.1	Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5- amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7- dimethyl-8-lumazine. The beta subunit catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)- pyrimidinedione with L-3,4-dihydrohy-2-butanone-4- phosphate yielding 6,7-dimethyl-8-lumazine (By similarity).
YP_003571144.1	nvolved in transformation (competence for DNA uptake)
YP_003571145.1	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
YP_003571146.1	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
YP_003571149.1	Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD- endopeptidase reaction (By similarity).
YP_003571153.1	Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300- 600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.
YP_003571169.1	Involved in protection of chromosomal DNA from damage under nutrient-limited and oxidative stress conditions. Binds heme (By similarity).
YP_003571170.1	The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another.
YP_003571174.1	Cystathionine beta-synthase (EC:4.2.1.22) that catalyzes the first irreversible step in homocysteine transulphuration
YP_003571180.1	Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'- phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differentiation.
YP_003571186.1	Cell wall formation (By similarity).
YP_003571188.1	Is a secondary, electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux. Makes modest contributions to pH homeostasis in the alkaline range of pH but is not contributor to Na(+) resistance. Appears to have a repressive effect on growth and on alkaline phosphatases production in the presence of sodium, by affecting the transcription of the phoP/phoR two-component regulatory system.
YP_003571192.1	S-adenosyl-L-homocysteine hydrolase (AdoHycase) catalyzes the hydrolysis of S-adenosyl-L-homocysteine (AdoHyc) to form adenosine (Ado) and homocysteine.
YP_003571198.1	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. This ferredoxin could play a role in regulating gene expression by interacting directly with DNA.
YP_003571199.1	The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination.
YP_003571229.1	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
YP_003571232.1	This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited.
YP_003571241.1	The mdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
YP_003571243.1	This enzyme is an endonuclease that degrades the RNA of DNA-DNA hybrids specifically (By similarity).
YP_003571244.1	predicted GTPase
YP_003571246.1	Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur- containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo (By similarity).
YP_003571248.1	Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA (By similarity).
YP_003571253.1	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
YP_003571255.1	Involved in the synthesis of Nod factor, a sulfated N-acyl-beta-1,4-tetrasaccharide of N- acetylglucosamine which initiates a series of events in the host plant species leading eventually to nodulation.
YP_003571265.1	Degrades short-lived regulatory and abnormal proteins in presence of ATP. Degrades the regulatory proteins rcsA and sulA. Hydrolyzes two ATPs for each peptide bond cleaved in the protein substrate (By similarity).
YP_003571269.1	Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that ttgR binds these antibiotics.
YP_003571270.1	Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids
YP_003571274.1	Catalyzes the dehydrogenation of acyl-CoA (By similarity).
YP_003571277.1	Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Also oxidizes the pathway intermediate coproporphyrinogen III.
YP_003571287.1	Supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone and menaquinone.
YP_003571289.1	Member of the two-component regulatory system atoS/atoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism.
YP_003571290.1	Deoxyribose-phosphate aldolase is involved in nucleotide metabolism.
YP_003571291.1	oxidoreductase activity
YP_003571308.1	Catalyses the transformation of HMG-CoA into acetyl-CoA and acetoacetate.
YP_003571314.1	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline
YP_003571317.1	Binds to NAD+ and NADH. In Salmonella it is required for resistance to antimicrobial peptides.
YP_003571319.1	The glycine cleavage system catalyzes the degradation of glycine.
YP_003571322.1	Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2.
YP_003571324.1	Involved in the assembly of outer membrane proteins.
YP_003571327.1	DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism.
YP_003571330.1	Selenoamino acid metabolism
YP_003571331.1	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation.
YP_003571332.1	Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia.
YP_003571336.1	Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of pullulanase.
YP_003571339.1	May be involved in pilus retraction.
YP_003571340.1	May be involved in pilus retraction.
YP_003571343.1	Involved in a general secretion pathway (GSP) for the export of proteins.
YP_003571345.1	Allows the formation of correctly charged Asn- tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.
YP_003571355.1	Involved in the conversion of glucose to GDP-L- fucose, which can be converted to L-fucose, a capsular polysaccharide.
YP_003571356.1	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction.
YP_003571362.1	May act at the level of sigma-G activity or its stability. SpoIID is probably required for engulfment.
YP_003571365.1	Acts as a chaperone
YP_003571366.1	involved in phospholipid biosynthesis
YP_003571370.1	Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide.
YP_003571378.1	Hydrolyzes peptides containing between 7 and 17 amino acids with a rather wide specificity.
YP_003571380.1	Required for resistance to DNA-damaging agents
YP_003571381.1	Required for resistance to DNA-damaging agents
YP_003571392.1	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YP_003571393.1	Converts adenosine 3'-phosphate 5'- phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Regulates the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. Involved in salt tolerance. Confers resistance to lithium.
YP_003571402.1	catalyzes the conversion of aspartate and carbamoyl phosphate to carbamoylaspartate, the second step in the de novo biosynthesis of pyrimidine nucleotides.
YP_003571403.1	The enzyme uracil phosphoribosyltransferase (UPRT ) catalyzes conversion of uracil to uridine 5'- monophosphate utilizing 5'-phosphoribosyl--1-pyrophosphate (PRPP).
YP_003571410.1	Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs
YP_003571417.1	Menaquinone biosynthesis
YP_003571418.1	menaquinone biosynthesis
YP_003571420.1	Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK).
YP_003571422.1	Converts 2-succinylbenzoate (OSB) to 2- succinylbenzoyl-CoA (OSB-CoA).
YP_003571426.1	In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts spoIIAB and thus releases sigma f from inhibition.
YP_003571431.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
YP_003571432.1	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YP_003571433.1	Binds together with S18 to 16S ribosomal RNA.
YP_003571434.1	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
YP_003571435.1	Binds to the 23S rRNA
YP_003571436.1	Involved in methionine biosynthesis
YP_003571437.1	Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus.
YP_003571438.1	4-hydroxyphenylpyruvate dioxygenase oxidizes 4- hydroxyphenylpyruvate, a tyrosine and phenylalanine catabolite, to homogentisate.
YP_003571443.1	Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.
YP_003571451.1	Participates in cysteine desulfuration mediated by sufS.
YP_003571453.1	Transport protein involved in the [Fe-S] cluster assembly.
YP_003571461.1	Anaerobic transformation of coproporphyrinogen- III into protoporphyrinogen-IX.
YP_003571466.1	Hydrolyzes most efficiently N-acetyl derivatives of aromatic amino acids but is also active on other amino acids. L-stereospecific.
YP_003571468.1	Hydrolyzes peptide amides
YP_003571476.1	Pantothenate biosynthesis
YP_003571480.1	Diaminopimelate epimerase catalyzes the isomeriazation of L,L- to D,L-meso-diaminopimelate in the biosynthetic pathway leading from aspartate to lysine.
YP_003571481.1	Peptidylprolyl isomerase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YP_003571485.1	This protein binds to 23S ribosomal RNA in the presence of protein L20.
YP_003571487.1	Oxidizes PNP and PMP into pyridoxal 5'- phosphate (PLP).
YP_003571488.1	Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
YP_003571489.1	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites
YP_003571490.1	Converts cytosolic UDP-MurNAc-tetrapeptides to tripeptides, the precursors for murein synthesis. Is essential for viability during stationary phase.
YP_003571495.1	Catalyzes the reaction from prephytoene diphosphate to phytoene.
YP_003571500.1	catalyses the condensation of L-aspartate-beta- semialdehyde and pyruvate to dihydropicolinic acid via a ping-pong mechanism in which pyruvate binds to the enzyme by forming a Schiff-base with a lysine residue
YP_003571504.1	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin- like activity.
YP_003571505.1	ephosphorylates several organic phosphomonoesters and catalyzes the transfer of low-energy phosphate groups from phosphomonoesters to hydroxyl groups of various organic compounds
YP_003571507.1	Degradation of inorganic polyphosphates.
YP_003571508.1	Oxidative phosphorylation
YP_003571509.1	Oxidative phosphorylation
YP_003571510.1	catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane.
YP_003571511.1	catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane.
YP_003571524.1	fatty acid metabolism
YP_003571525.1	atalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
YP_003571529.1	catalyzes the conversion of glycerol-3- phosphate into dihydroxyacetone phosphate.
YP_003571537.1	Key enzyme in the regulation of glycerol uptake and metabolism.
YP_003571539.1	Catalyses the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate.
YP_003571542.1	hydratation of 2-trans-enoyl-CoA into 3- hydroxyacyl-CoA.
YP_003571543.1	catalyzes the reversible, stereo-specific, isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle, a non-redox active process.
YP_003571544.1	Terpenoid biosynthesis
YP_003571545.1	purine biosynthetic pathway
YP_003571547.1	Catalyses the interconversion of dihydroxyacetone phosphate and L-glycerol-3-phosphate.
YP_003571549.1	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.
YP_003571550.1	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.
YP_003571562.1	arbohydrate transport and metabolism
YP_003571565.1	Participates to chromosomal partition during cell division. May act via the formation of a condensin- like complex containing smc and scpA that pull DNA away from mid-cell into both cell halves
YP_003571566.1	Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA
YP_003571567.1	catalyzes the rate-limiting reaction of de novo GTP biosynthesis, the NAD-dependent reduction of IMP into XMP.
YP_003571568.1	Xaa-Pro dipeptidase (prolidase) splits dipeptides with a prolyl residue in the carboxyl terminal position.
YP_003571570.1	Catalyzes the first step in the biosynthesis of 2-methylthio-N6-(delta(2)-isopentenyl)-adenosine adjacent to the anticodon of several tRNA species.
YP_003571572.1	atalyzes the reaction from prephytoene diphosphate to phytoene.
YP_003571573.1	This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds.
YP_003571577.1	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.
YP_003571579.1	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.
YP_003571581.1	transforms dihydroneopterin triphosphate into 6- pyruvoyltetrahydropterin in the presence of Mg(II).
YP_003571586.1	catalyzes the seventh step in the de novo purine biosynthetic pathway; the ATP-dependent conversion of 5'-phosphoribosyl-5-aminoimidazole-4-carboxylic acid and aspartic acid to SAICAR.
YP_003571590.1	Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon
YP_003571598.1	3-dehydroquinate (DHQ) synthase catalyses the formation of dehydroquinate (DHQ) and orthophosphate from 3-deoxy-D-arabino heptulosonic 7 phosphate.
YP_003571600.1	3'-5'exoribonuclease that participates in an essential cell function.
YP_003571603.1	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP- dependent hybridization of homologous single-stranded DNAs.
YP_003571610.1	Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols.
YP_003571611.1	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.
YP_003571616.1	Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7- methylguanine, O2-methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions.
YP_003571621.1	Degrades an unidentified toxic product from the first step of tartrate degradation.
YP_003571623.1	Condenses 4-methyl-5-(beta- hydroxyethyl) thiazole monophosphate (THZ-P) and 4-amino-5- hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate
YP_003571624.1	Uroporphyrinogen III synthase (HEM4) catalyses the fourth step in the heme biosynthetic pathway in eukaryotes, bacteria and archaea.
YP_003571625.1	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
YP_003571626.1	catalyzes the Mg 2+ /NADPH-dependent conversion of glutamate- tRNA(Glu) to glutamate-1- semialdehyde (GSA) with the concomitant release of tRNA(Glu) which can then be recharged with glutamate by glutamyl-tRNA synthetase.
YP_003571627.1	Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine.
YP_003571628.1	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
YP_003571630.1	Imidazoleglycerol-phosphate dehydratase is the enzyme that catalyzes the seventh step in the biosynthesis of histidine in bacteria, fungi and plants.
YP_003571632.1	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The hisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to hisF for the synthesis of IGP and AICAR
YP_003571634.1	catalyses the fourth step in histidine biosynthesis.
YP_003571635.1	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The hisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the hisH subunit
YP_003571639.1	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.
YP_003571641.1	Catalyzes the reversible oxidation of malate to oxaloacetate
YP_003571643.1	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S- lactoylglutathione.
YP_003571650.1	UvrC both incises the 5' and 3' sides of the lesion.
YP_003571662.1	Azurin, found in bacteria, is thought to transfer electrons from cytochrome c551 to cytochrome oxidase.
YP_003571664.1	Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4- benzoquinol (DMQH2)
YP_003571666.1	Involved in copper efflux
YP_003571668.1	Could be part of an electron transfer system required for anaerobic carnitine reduction.
YP_003571676.1	Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes.
YP_003571681.1	This protein is involved in the repair of mismatches in DNA.
YP_003571682.1	Required for resistance to DNA-damaging agents
YP_003571684.1	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus
YP_003571687.1	catalyzes the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD
YP_003571689.1	involved in tyrosine biosynthesis.
YP_003571690.1	The glycine cleavage system catalyzes the degradation of glycine.
YP_003571691.1	catalyzes the sulfonation of phosphoenolpyruvate to form 2-phospho-3-sulfolactate
YP_003571692.1	DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation.
YP_003571693.1	Possesses an ATPase activity that is dependent on the presence of AIR.
YP_003571694.1	This subunit can alone transform AIR to CAIR, but in association with purK, which possesses an ATPase activity, an enzyme complex is produced which is capable of converting AIR to CAIR efficiently under physiological condition.
YP_003571695.1	Lysine-specific endoprotease. Involved in corneal virulence.
YP_003571697.1	Binds specifically to the ssrA RNA (tmRNA) and is required for stable association of ssrA with ribosomes
YP_003571699.1	his protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
YP_003571700.1	Specifically methylates guanosine-37 in various tRNAs.
YP_003571701.1	Essential for efficient processing of 16S rRNA.
YP_003571703.1	Necessary for efficient export of extra- cytoplasmic proteins.
YP_003571708.1	this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity
YP_003571710.1	Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.
YP_003571714.1	catalysing the last two steps in de novo purine biosynthesis
YP_003571716.1	Involved in formation of the rod shape of the cell.
YP_003571717.1	Protease subunit of a proteasome-like degradation complex.
YP_003571719.1	Chaperone subunit of a proteasome-like degradation complex.
YP_003571725.1	Converts 4-diphosphocytidyl-2-C-methyl-D- erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (MECDP) and CMP.
YP_003571726.1	Catalyzes the formation of 4-diphosphocytidyl-2- C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate.
YP_003571727.1	Synthesizes oQ from preQ1 in a single S- adenosylmethionine-requiring step.
YP_003571729.1	Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.
YP_003571733.1	Potential transporter for phosphate.
YP_003571740.1	L-tryptophan biosynthesis
YP_003571742.1	L-tryptophan biosynthesis
YP_003571743.1	Catalyzes the biosynthesis of 4-amino-4- deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate.
YP_003571744.1	L-tryptophan biosynthesis
YP_003571745.1	L-tryptophan biosynthesis
YP_003571746.1	L-tryptophan biosynthesis
YP_003571747.1	The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
YP_003571748.1	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
YP_003571751.1	Involved in the recF recombination pathway.
YP_003571754.1	isocitrate metabolism
YP_003571761.1	nables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt.
YP_003571762.1	Catalyzes the biosynthesis of 4-amino-4- deoxychorismate (ADC) from chorismate and glutamine.
YP_003571763.1	Alcohol dehydrogenase catalyzes the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD.
YP_003571767.1	Catalyzes the interconversion of succinyl-CoA and methylmalonyl-CoA during the polyhydroxyalkanoate degradation pathway.
YP_003571769.1	Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis.
YP_003571771.1	Mrp complex is a Na(+)/H(+) antiporter involved in Na(+) excretion and Na(+) resistance.
YP_003571772.1	Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
YP_003571773.1	nh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
YP_003571774.1	May enhance mrpA stability, assembly, or function. May play chaperone or assembly roles for mrpA and perhaps for other mrp proteins.
YP_003571775.1	Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis.Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis.
YP_003571781.1	Porphyrin biosynthesis.
YP_003571782.1	Ring cleavage of cyclic ester dienelactone to produce maleylacetate.
YP_003571783.1	Phospholipid biosynthesis.
YP_003571788.1	aromatic amino acid family metabolism
YP_003571789.1	catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion
YP_003571790.1	This enzyme acts exclusively on hypoxanthine; it does not act on guanine
YP_003571792.1	This protein is involved in the repair of mismatches in DNA.
YP_003571793.1	Phospholipid biosynthesis.
YP_003571798.1	drug/sodium antiporters
YP_003571808.1	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
YP_003571816.1	Arginine biosynthesis
YP_003571818.1	Nucleotide biosynthesis
YP_003571820.1	Required for resistance to DNA-damaging agents
YP_003571821.1	Required for resistance to DNA-damaging agents
YP_003571825.1	Porphyrin biosynthesis by the C5 pathway
YP_003571827.1	Catalyzes the ferrous insertion into protoporphyrin IX.
YP_003571828.1	Porphyrin biosynthesis
YP_003571829.1	Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
YP_003571831.1	catalyzes the phosphorylation of aspartate.
YP_003571834.1	Removes C-terminal D-alanyl residues from sugar- peptide cell wall precursors. Binds penicillin.
YP_003571840.1	DNA repair
YP_003571843.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
YP_003571844.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
YP_003571847.1	This protein binds directly to 23S rRNA and is located in the neighborhood of the site where elongation factor Tu is bound to the ribosome
YP_003571848.1	This protein binds directly to 23S ribosomal RNA
YP_003571849.1	Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase
YP_003571850.1	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
YP_003571856.1	Participates in chromosomal partition during cell division. May act via the formation of a condensin- like complex containing smc and scpB that pull DNA away from mid-cell into both cell halves
YP_003571858.1	Involved in mRNA degradation. Hydrolyzes single- stranded polyribonucleotides processively in the 3' to 5' direction
YP_003571865.1	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YP_003571871.1	Malic enzymes (malate oxidoreductases) catalyse the oxidative decarboxylation of malate to form pyruvate [ 1 ], a reaction important in a number of metabolic pathways - e.g. carbon dioxide released from the reaction may be used in sugar production during the Calvin cycle of photosynthesis
YP_003571872.1	Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
YP_003571876.1	Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl- CoA to the tricarboxylic acid cycle
YP_003571877.1	Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates
YP_003571880.1	ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA
YP_003571881.1	ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)
YP_003571882.1	PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins
YP_003571884.1	Chaperone involved in the folding of extracytoplasmic proteins. Required for the efficient folding of ompA, ompF and lamB. Essential for the survival of E.coli in stationary phase
YP_003571885.1	May be involved in the regulation of formation of active methanol dehydrogenase
YP_003571886.1	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by nqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
YP_003571887.1	The molecular function of FxsA is unknown, but in Escherichia coli its overexpression has been shown to alleviate the exclusion of phage T7 in those cells with an F plasmid
YP_003571890.1	Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide
YP_003571891.1	he enzyme complex may have a wide variety of catalytic activities including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent helicase and DNA-dependent ATPase activities. The subunit A may have a role in DNA unwinding (helicase), and in the nuclease activity
YP_003571900.1	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YP_003571901.1	Seems to act as an ATP-dependent zinc metallopeptidase
YP_003571909.1	# Plays an important role in the de novo pathway of purine nucleotide biosynthesis.
YP_003571910.1	Involved in protein export
YP_003571911.1	Involved in protein export
YP_003571915.1	catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two- step reaction.
YP_003571917.1	catalyzes the formation of phosphoenolpyruvate by decarboxylation of oxaloacetate while hydrolyzing ATP, a rate limiting step in gluconeogenesis (the biosynthesis of glucose)
YP_003571919.1	This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp
YP_003571923.1	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YP_003571928.1	Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide
YP_003571930.1	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C- methyl-D-erythritol 4-phosphate (MEP)
YP_003571935.1	Cell envelope biogenesis
YP_003571936.1	catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two- step reaction
YP_003571939.1	Catalyzes the removal of elemental sulfur from cysteine to produce alanine
YP_003571940.1	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
YP_003571943.1	catalyzes the second step in the de novo biosynthesis of purine
YP_003571946.1	Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N- acetylglucosamine, that stimulates mitosis in various plant protoplasts
YP_003571947.1	Binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.This protein also expresses aconitase activity
YP_003571953.1	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
YP_003571955.1	Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate which is a precursor of the ether-linked lipids
YP_003571956.1	This small ubiquitous enzyme is essential for maintenance and cell growth
YP_003571961.1	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4- diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)
YP_003571970.1	Hydrolyzes diadenosine polyphosphate
YP_003571978.1	Aminopeptidase with broad substrate specificity to several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity
YP_003571983.1	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YP_003571986.1	Allows the formation of correctly charged Asn- tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YP_003571989.1	D-glyceraldehyde 3-phosphate = glycerone phosphate.
YP_003571996.1	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YP_003571997.1	catalyses the conversion of nicotinate D- ribonucleotide, pyrophosphate and carbon dioxide into pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1- diphosphate.
YP_003571998.1	Catalyzes the oxidation of L-aspartate to iminoaspartate
YP_003572011.1	The enzyme catalyzes the hydrolysis of N- carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. Industrial production of beta-lactam antibiotics is now being developed using this enzyme
YP_003572021.1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing in the extracytoplasmic compartment
YP_003572028.1	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YP_003572031.1	Involved in protection of the bacterium from thermal and osmotic stresses
YP_003572033.1	Catalyzes the methyl esterification of L- isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L- asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins
YP_003572035.1	DHPS catalyzes the formation of the immediate precursor of folic acid. It is implicated in resistance to sulfonamide
YP_003572036.1	Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin. Strongly reactive with Glu, Gln, Trp, Asp, Ala, Leu, Phe, Gly, Tyr, Met, Ile and Val. Little or no product formation with His, Ser, Thr, Arg, Lys, or Cys. Also active on pyruvic and butyric acid analogs of IAA, PAA and the synthetic auxin naphthaleneacetic acid (NAA). The two chlorinated synthetic auxin herbicides 2,4-D and 3,6-dichloro-o-anisic acid (dicamba) cannot be used as substrates
YP_003572037.1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium
YP_003572039.1	Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel
YP_003572050.1	This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
YP_003572055.1	The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2)
YP_003572059.1	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) . It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3)
YP_003572063.1	Probably mediates the hydrolysis of some nucleoside diphosphate derivatives
YP_003572077.1	Required for resistance to DNA-damaging agents
YP_003572078.1	The most conserved residues are probably involved in metal binding and catalysis.
YP_003572085.1	In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity. Intein encoded endonucleases are thought to mediate intein mobility by site-specfic recombination initiated by endonuclease cleavage at the
YP_003572089.1	Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules
YP_003572090.1	is the enzyme responsible for the hydrolysis of pyrophosphate (PPi) which is formed principally as the product of the many biosynthetic reactions that utilize ATP.
YP_003572109.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
YP_003572117.1	Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light- induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports one Ca(2+) and one K(+) in exchange for four Na(+)
YP_003572124.1	Fatty acid biosynthesis pathway; first reduction step
YP_003572129.1	involved in sulphur transfer
YP_003572130.1	Involved in the biosynthesis of a demolybdo cofactor (molybdopterin), necessary for molybdoenzymes.
YP_003572132.1	Catalyzes the attachment of valine to tRNA(Val)
YP_003572133.1	Iron-binding repressor of siderophore biosynthesis and iron uptake
YP_003572146.1	catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane.
YP_003572148.1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon interaction with the dnaJ-bound protein, dnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from dnaK; ATP binding to dnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between dnaJ, dnaK and grpE are required for fully efficient folding. Also involved, together with dnaK and grpE, in the DNA replication of plasmids through activation of initiation proteins
YP_003572149.1	This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds
YP_003572152.1	catalyzes the last of the seven steps in the shikimate pathway which is used in prokaryotes, fungi and plants for the biosynthesis of aromatic amino acids
YP_003572156.1	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes
YP_003572157.1	Methylates the translation termination release factor RF1 on Gln-235 and RF2 on Gln-252
YP_003572158.1	catalyses the hydrolysis of the carboxyl- phosphate bond of acylphosphates
YP_003572161.1	Antioxidant. Reduces peroxides with reducing equivalent provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism
YP_003572162.1	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
YP_003572165.1	Catalyzes the synthesis of GMP from XMP
YP_003572166.1	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
YP_003572167.1	Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YP_003572170.1	Catalyzes the condensation of 1-deoxy-D- xylulose-5-phosphate (DXP) and 1-amino-3- (phosphohydroxy) propan-2-one to form pyridoxine 5'- phosphate (PNP)
YP_003572171.1	Binds both GDP and GTP, has an intrinsic GTPase activity and is essential for cell growth
YP_003572172.1	Catalyzes the oxidation of erythronate-4- phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate
YP_003572176.1	The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These are enzymes that catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds
YP_003572177.1	Can hydrolyze carbapenem compounds
YP_003572190.1	Subunits I, II and III form the functional core of the enzyme complex
YP_003572191.1	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YP_003572192.1	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.
YP_003572209.1	Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process
YP_003572214.1	Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities
YP_003572217.1	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YP_003572218.1	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
YP_003572219.1	Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids
YP_003572224.1	Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine
YP_003572225.1	The biosynthesis of histidine is a central metabolic process in organisms ranging from bacteria to yeast and plants. The seventh step in the synthesis of histidine within eubacteria is carried out by a pyridoxal- 5'-phosphate (PLP)-dependent l-histidinol phosphate aminotransferase (HisC, 2.6.1.9 ).
YP_003572228.1	Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules.
YP_003572230.1	Modulates recA activity
YP_003572234.1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YP_003572236.1	The function of RlpA is not well understood, but it has been shown to act as a prc mutant suppressor in Escherichia coli
YP_003572237.1	Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase
YP_003572241.1	Acetohydroxy acid isomeroreductase catalyses the conversion of acetohydroxy acids into dihydroxy valerates.
YP_003572242.1	Catalyzes the oxidation of 3-carboxy-2-hydroxy- 4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4- methyl-2-oxopentanoate. The product decarboxylates to 4- methyl-2 oxopentanoate
YP_003572243.1	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2- oxoisovalerate) to form 3-carboxy-3-hydroxy-4- methylpentanoate (2-isopropylmalate)
YP_003572244.1	Catalyzes the isomerization between 2- isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YP_003572246.1	Catalyzes the isomerization between 2- isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YP_003572248.1	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2- oxoisovalerate) to form 3-carboxy-3-hydroxy-4- methylpentanoate (2-isopropylmalate)
YP_003572254.1	Catalyzes the formation of methylthio-D-ribose 1-phosphate (MTR-1-P) from methylthioadenosine (MTA)
YP_003572258.1	Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'trailer from precursor tRNA
YP_003572263.1	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate- dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr)
YP_003572265.1	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N- formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP
YP_003572266.1	Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein)
YP_003572267.1	his protein catalyzes the committed step to the synthesis of the acidic phospholipids
YP_003572275.1	Repair of alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme.
YP_003572281.1	Cell wall formation
YP_003572287.1	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YP_003572288.1	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YP_003572293.1	Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance
YP_003572296.1	Cell wall formation
YP_003572297.1	catalyzes the third step in the de novo biosynthesis of pyrimidine, the conversion of ureidosuccinic acid (N-carbamoyl-L-aspartate) into dihydroorotate.
YP_003572298.1	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings
YP_003572303.1	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YP_003572304.1	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YP_003572305.1	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YP_003572306.1	catalyse the conversion of O-phospho-L-serine and oxoglutarate to 3-phosphonooxypyruvate and L-glutamate in the major phosphorylated serine biosynthesis pathway. In bacteria it is also equired for the biosynthesis of pyridoxine
YP_003572307.1	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
YP_003572311.1	Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation.
YP_003572314.1	Argininosuccinate synthase ( 6.3.4.5 ) (AS) is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate
YP_003572316.1	It's involved in arginine biosynthesis
YP_003572317.1	Arginine biosynthesis
YP_003572318.1	catalyzes the conversion of ornithine and carbamoyl phosphate to citrulline
YP_003572319.1	it is the first intermediate in the biosynthesis of arginine
YP_003572320.1	Catalyse the final step in arginine biosynthesis. Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde
YP_003572321.1	Omega-N-(L-arginino)succinate = fumarate + L- arginine.
YP_003572324.1	Photoactive blue-light protein. Probably functions as a photoreceptor for a negative phototaxis response.
YP_003572334.1	Required for many types of recombinational events, although the stringency of the requirement for recJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available
YP_003572335.1	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YP_003572338.1	Required for the rotation of the flagellar motor. Might be a linker that fastens the torque- generating machinery to the cell wall.
YP_003572340.1	The directed movement of sulfate into, out of, within or between cells
YP_003572346.1	carboxylation of acetyl-CoA to malonyl-CoA
YP_003572349.1	This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing in the extracytoplasmic compartment
YP_003572355.1	May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate
YP_003572362.1	Part of a potassium transport system
YP_003572366.1	Part of a potassium transport system
YP_003572368.1	This protein is required for high-affinity potassium transport
YP_003572369.1	Part of a potassium transport system
YP_003572370.1	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity
YP_003572371.1	Transport system that facilitates potassium- efflux, possibly by potassium-proton antiporter
YP_003572372.1	# Transport system that facilitates potassium- efflux, possibly by potassium-proton antiport.
YP_003572376.1	involved in the biosynthesis of aromatic amino acids.
YP_003572383.1	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation
YP_003572387.1	Catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia
YP_003572392.1	Required for binding-protein-mediated phosphate transport
YP_003572393.1	Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane
YP_003572394.1	Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane
YP_003572395.1	Part of the ABC transporter complex pstSACB involved in phosphate import. Responsible for energy coupling to the transport system
YP_003572396.1	probably involved in phosphate transport and/or metabolism
YP_003572400.1	Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position
YP_003572401.1	Converts 2,5-diamino-6-(ribosylamino)-4(3h)- pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)- 2, 4(1h,3h)-pyrimidinedione 5'-phosphate
YP_003572402.1	# Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5- amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7- dimethyl-8-lumazine. The alpha subunit catalyzes the dismutation of 6,7-dimethyl-8-lumazine to riboflavin and 5- amino-6-(1'-D)-ribityl-amino-2,4(1H,3H) -pyrimidinedione.
YP_003572406.1	catalyzes the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD.
YP_003572409.1	Since only maltooligosaccharides up to a chain length of 6 glucose units are actively transported through the cytoplasmic membrane via the membrane-bound complex of three proteins, malF, malG, and malK, longer maltooligosaccharides must first be degraded by the periplasmic alpha-amylase, the malS protein.
YP_003572413.1	Catalyzes the methyl esterification of L- isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L- asparaginyl residues.
YP_003572416.1	Acts on leucine, isoleucine and valine
YP_003572417.1	Regulates polyamine concentration by their degradation. Acts on spermidine, forming 1-N- and 8-N- acetylspermidine
YP_003572418.1	Involved in chlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX
YP_003572425.1	catalyses the oxidation of long-chain aldehydes and releases energy in the form of visible light
YP_003572427.1	This enzyme catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand, upon exposure to ultraviolet radiation.
YP_003572428.1	can protect other proteins against heat-induced denaturation and aggregation.
YP_003572429.1	Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4- benzoquinol (DMQH2)
YP_003572431.1	catalyse the attachment of glycyl to its cognate transfer RNA molecule in a highly specific two- step reaction
YP_003572433.1	Involved in DNA repair
YP_003572434.1	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YP_003572436.1	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl- pentapeptide, the precursor of murein.
YP_003572439.1	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes
YP_003572442.1	This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
YP_003572444.1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
YP_003572445.1	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with dnaK and grpE. It is the nucleotide exchange factor for dnaK and may function as a thermosensor.
YP_003572446.1	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
YP_003572447.1	Digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane
YP_003572448.1	Catalyzes the interconversion of 2- phosphoglycerate and 3-phosphoglycerate
YP_003572453.1	Fumarylacetoacetate hydrolase is the last enzyme of the tyrosine catabolic pathway, and deficiency in this enzyme causes Tyrosinemia type I, an inborn error of metabolism
YP_003572456.1	Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur- containing biomolecules.
YP_003572458.1	ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
YP_003572460.1	Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS O antigen.
YP_003572461.1	Required for cytochrome aa3 biosynthesis and independently for sporulation.
YP_003572465.1	Endonuclease that specifically degrades the RNA of RNA-DNA hybrids
YP_003572466.1	catalyzes the formation of phosphoenolpyruvate by decarboxylation of oxaloacetate while hydrolyzing ATP, a rate limiting step in gluconeogenesis (the biosynthesis of glucose) . It is involved in the glyoxylate bypass, an alternative to the tricarboxylic acid cycle in bacteria, fungi and plants.
YP_003572467.1	This enzyme converts phytoene into zeta- carotene via the intermediary of phytofluene by the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene.
YP_003572468.1	hydrolyses adenine to form hypoxanthine and ammonia
YP_003572470.1	It is involved in threonine biosynthesis
YP_003572472.1	Catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids.
YP_003572473.1	Pyrimidine biosynthesis
YP_003572476.1	# Cell wall formation; PBP-2 is responsible for the determination of the rod shape of the cell. Its synthesize cross-linked peptidoglycan from the lipid intermediates.
YP_003572477.1	This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division
YP_003572479.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YP_003572484.1	Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).
YP_003572491.1	Part of the ABC transporter complex fbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system
YP_003572492.1	Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. Probably responsible for the translocation of the substrate across the membrane
YP_003572493.1	Part of the ABC transporter complex fbpABC (TC 3.A.1.10.1) involved in Fe(3+) ions import. This protein specifically binds Fe(3+) and is involved in its transmembrane transport
YP_003572498.1	Bifunctional, exhibiting both a catalase and broad-spectrum peroxidase activities.
YP_003572499.1	Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione-reductase.
YP_003572501.1	Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
YP_003572502.1	O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety.
YP_003572511.1	Conversion of folates to polyglutamate derivatives.
YP_003572513.1	Converts HMG-CoA to mevalonate
YP_003572517.1	ATP + thiamine phosphate = ADP + thiamine diphosphate.
YP_003572520.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is the catalytic subunit.
YP_003572521.1	Produces ATP from ADP in the presence of a proton gradient across the membrane.
YP_003572524.1	Provides the D-alanine required for cell wall biosynthesis.
YP_003572527.1	tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA.
YP_003572530.1	Glycerophospholipid metabolism
YP_003572538.1	Protein phosphorylation plays a central role in the regulation of cell function causing the activation or inhibition of many enzymes involved in various biochemical pathways.
YP_003572539.1	Alkaline phosphatase is a zinc and magnesium- containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH.
YP_003572540.1	participates in iron transport.
YP_003572543.1	This group of enzymes represents a large metal dependent hydrolase superfamily.
YP_003572545.1	Folate biosynthesis.
YP_003572547.1	hydrolysis of phosphoric acid anhydride.
YP_003572549.1	Three genes, crcA, cspE and crcB when present in high copy confer camphor resistance on a cell and suppress mutations in the chromosomal partition gene mukB in Escherichia coli.
YP_003572553.1	Involved in resistance to arsenic compounds.
YP_003572565.1	This domain is a part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation.
YP_003572566.1	This family of domains are likely to bind to zinc ions.
YP_003572571.1	ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances across cellular membranes.
YP_003572575.1	eleases amino acids sequentially from the C- terminus with a broad substrate specificity (except for proline)
YP_003572578.1	Members of the 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthetase family catalyse the first step in aromatic amino acid biosynthesis from chorismate.
YP_003572583.1	tRNA (5-methylaminomethyl-2-thiouridylate)- methyltransferase catalyses the addition of 5- methylaminomethyl-2-thiouridylate to tRNAs using S- adenosyl-L-methionine as a substrate and releasing S- adenosyl-L-homocysteine.
YP_003572584.1	This domain is found in endoribonuclease, that is active on single-stranded mRNA and inhibits protein synthesis by cleavage of mRNA. Previously it was thought to inhibit protein synthesis initiation. This endoribonuclease may also be involved in the regulation of purine biosynthesis.
YP_003572586.1	Autolysin hydrolyses the link between N- acetylmuramoyl residues and L-amino acid residues in certain bacterial cell wall glycopeptides.
YP_003572588.1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing in the extracytoplasmic compartment
YP_003572589.1	May play a role in the repair of endogenous alkylation damage.
YP_003572606.1	Involved in the control of phototaxis. Mediates both photoattractant (in the red) and photophobic (in the near UV) responses. Seems to activate a methyl-accepting protein (HTR-I).
YP_003572614.1	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
YP_003572620.1	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine
YP_003572621.1	atalyzes the reversible isomerization- deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
YP_003572628.1	Bacterial transcription regulatory proteins that bind DNA via a helix-turn-helix (HTH) motif can be grouped into families on the basis of sequence similarities.
YP_003572632.1	tRNA synthetases, or tRNA ligases are involved in protein synthesis.
YP_003572636.1	Could be a metalloprotease.
YP_003572639.1	no known function
YP_003572644.1	Catalyzes the transfer of the endogenously synthesized lipoate to apoproteins, creating an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoate-dependent enzymes. Utilizes lipoyl-acyl-carrier protein as a source of lipoyl groups, although octanoyl groups from octanoyl-ACP can also be transferred to the lipoyl domain of apoproteins
YP_003572647.1	May play a role in DNA repair. It seems to be involved in an recBC-independent recombinational process of DNA repair. It may act with recF and recO.
YP_003572649.1	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
YP_003572651.1	ATP + thymidine = ADP + thymidine 5'- phosphate.
YP_003572652.1	unknown function
YP_003572653.1	transporting small solutes
YP_003572655.1	Regulates the expression of the alsSD operon for acetoin biosynthesis.
YP_003572663.1	Modulates the activity of chromatin proteins, thereby having an effect on transcription.
YP_003572668.1	Could be required for maximum PGA (gamma- polyglutamic acid) production.
YP_003572673.1	Transcription.
YP_003572676.1	Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.
YP_003572677.1	Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin.
YP_003572678.1	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin.
YP_003572679.1	Role in flagellar biosynthesis
YP_003572680.1	Role in flagellar biosynthesis
YP_003572681.1	Plays a role in the flagellum-specific transport system.
YP_003572683.1	FliN is one of three proteins (fliG, fliN, fliM) that form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with the cheY and cheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
YP_003572684.1	FliM is one of three proteins (fliG, fliN, fliM) that form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with the cheY and cheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
YP_003572685.1	ontrols the rotational direction of flagella during chemotaxis.
YP_003572686.1	Required for the rotation of the flagellar motor. Might be a linker that fastens the torque- generating machinery to the cell wall.
YP_003572687.1	Required for rotation of the flagellar motor. Probable transmembrane proton channel.
YP_003572690.1	Cell motility and secretion / Signal transduction mechanisms
YP_003572692.1	Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation.
YP_003572693.1	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
YP_003572694.1	Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by cheR.
YP_003572695.1	Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either cheB or cheY.
YP_003572698.1	Methylation of the membrane-bound methyl- accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
YP_003572699.1	nvolved in the transmission of sensory signals from the chemoreceptors to the flagellar motors.
YP_003572702.1	Required for flagellar hook formation. May act as a scaffolding protein.
YP_003572706.1	It is needed for flagellar assembly, its ATPase activity is required for flagellation, and it may be involved in a specialized protein export pathway that proceeds without signal peptide cleavage.
YP_003572708.1	FliG is one of three proteins (fliG, fliN, fliM) that form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with the cheY and cheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
YP_003572709.1	he M ring may be actively involved in energy transduction.
YP_003572714.1	Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54.
YP_003572717.1	equired for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential for motility. Responsible for adhesion to mucin, which is the initial event in colonization by this organism of the airways of cystic fibrosis patients.
YP_003572718.1	Not known.
YP_003572726.1	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaA is required to form a core or scaffold into which the other flagellins are inserted to provide structural integrity. Essential for flagellar synthesis and motility; important for full virulence.
YP_003572729.1	Flagellar assembly
YP_003572733.1	Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
YP_003572734.1	Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
YP_003572747.1	omponent of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
YP_003572750.1	catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate).
YP_003572758.1	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'terminal phosphate and a 3'terminal hydroxyl group.
YP_003572762.1	Involved in ATP-dependent electrogenic sodium extrusion
YP_003572763.1	nvolved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.
YP_003572764.1	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin- like activity. Plays a major role in the degradation of misfolded proteins.
YP_003572765.1	lays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
YP_003572774.1	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6- hydroxy-phenol, the fourth step in ubiquinone biosynthesis. Required for the expression of 2'-N- acetyltransferase.
YP_003572776.1	Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
YP_003572779.1	Catalyzes the ferrous insertion into protoporphyrin IX.
YP_003572782.1	Required for the rotation of the flagellar motor. Might be a linker that fastens the torque- generating machinery to the cell wall.
YP_003572785.1	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
YP_003572786.1	Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer- membrane proteins including the iron transport operon.
YP_003572789.1	dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O.
YP_003572792.1	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm, thereby maintaining the active site of dsbC, dsbE and dsbG in a reduced state. This transfer involves a cascade of disulfide bond formation and reduction steps.
YP_003572799.1	Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
YP_003572803.1	This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
YP_003572808.1	Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism.
YP_003572809.1	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein tonB.
YP_003572810.1	Part of the ABC transporter complex btuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of btuC.
YP_003572811.1	Part of the ABC transporter complex btuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
YP_003572814.1	Part of the binding-protein-dependent transport system for hemin.
YP_003572817.1	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein tonB.
YP_003572822.1	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis.
YP_003572829.1	Recognizes a specific hairpin sequence on phiX ssDNA. This structure is then recognized and bound by proteins priB and priC. Formation of the primosome proceeds with the subsequent actions of dnaB, dnaC, dnaT and primase. PriA then functions as a helicase within the primosome.
YP_003572832.1	Catalyzes the dephosphorylation of the artificial chromogenic susbtrate p-nitrophenyl phosphate (pNPP) and of the natural substrate glucose 6-phosphate.
YP_003572835.1	equired for proper expression of outer membrane protein genes such as ompF, nmpC, protein 2, hemolysin, colicin V, or colicin E1. May be specialized for signal sequence independent, extracellular secretion in Gram- negative bacteria.
YP_003572837.1	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis.
YP_003572838.1	Carrier of the growing fatty acid chain in fatty acid biosynthesis.
YP_003572839.1	Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
YP_003572841.1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
YP_003572845.1	catalyze the hydrolysis of asparagine (or glutamine) to aspartate (or glutamate) and ammonia.
YP_003572846.1	igma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing in the extracytoplasmic compartment.
YP_003572850.1	Release of an N-terminal dipeptide, Xaa-Yaa-|- Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline
YP_003572852.1	Converts O-succinylbenzoyl-CoA (OSB-CoA) to 1, 4- dihydroxy-2-naphthoic acid (DHNA)
YP_003572862.1	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
YP_003572863.1	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
YP_003572864.1	Is a secondary, electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux. Makes modest contributions to pH homeostasis in the alkaline range of pH but is not contributor to Na(+) resistance. Appears to have a repressive effect on growth and on alkaline phosphatases production in the presence of sodium, by affecting the transcription of the phoP/phoR two-component regulatory system.
YP_003572866.1	Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells.
YP_003572867.1	Light-driven chloride pump.
YP_003572868.1	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
YP_003572871.1	Ubiquinone biosynthesis, Oxidative phosphorylation
YP_003572874.1	Glycine, serine and threonine metabolism, Methionine metabolism, Selenoamino acid metabolism.
YP_003572875.1	Involved in the transposition of the insertion sequence.
YP_003572880.1	Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatases genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals.
YP_003572881.1	Catalyzes the phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A
YP_003572889.1	Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde.
YP_003572890.1	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair.
YP_003572891.1	catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two- step reaction.
YP_003572892.1	F-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
YP_003572894.1	This protein binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
YP_003572902.1	Hydrolyzes chitin oligosaccharides; (GlcNAc)4 to (GlcNAc)2 and (GlcNAc)5,6 to (GlcNAc)2 and (GlcNAc)3. Inactive towards chitin, glucosamine oligosaccharides, glycoproteins and glycopeptides containing (GlcNAc)2
YP_003572906.1	Kills cells. Doc and phd proteins function in unisson to stabilize plasmid number by inducing a lethal response to plasmid loss.
YP_003572907.1	hiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from ccdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached.
YP_003572908.1	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm, thereby maintaining the active site of dsbC, dsbE and dsbG in a reduced state. This transfer involves a cascade of disulfide bond formation and reduction steps.
YP_003572915.1	Has a low cation transport activity for cobalt, it is essential for the expression of cobalt, zinc, and cadmium resistance. CzcA and czcB together would act in zinc efflux nearly as effectively as the complete CZC efflux system.
YP_003572916.1	P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents NR-II- catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylylation of glutamine synthetase by glnE, so activating the enzyme.
YP_003572922.1	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Acts before dnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of clpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by dnaK (By similarity).
YP_003572926.1	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
YP_003572933.1	Shows activity on lichenan, beta-glucan and laminarin but not on CMC cellulose or xylan.
YP_003572945.1	Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism.
YP_003572946.1	Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism.
YP_003572957.1	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S- lactoylglutathione