-- dump date   	20140620_043127
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
882884000001	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
882884000002	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
882884000003	active site
882884000004	tetramer interface [polypeptide binding]; other site
882884000005	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
882884000006	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
882884000007	active site
882884000008	tetramer interface [polypeptide binding]; other site
882884000009	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
882884000010	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
882884000011	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
882884000012	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884000013	dimerization interface [polypeptide binding]; other site
882884000014	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884000015	dimer interface [polypeptide binding]; other site
882884000016	phosphorylation site [posttranslational modification]
882884000017	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884000018	ATP binding site [chemical binding]; other site
882884000019	Mg2+ binding site [ion binding]; other site
882884000020	G-X-G motif; other site
882884000021	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
882884000022	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884000023	active site
882884000024	phosphorylation site [posttranslational modification]
882884000025	intermolecular recognition site; other site
882884000026	dimerization interface [polypeptide binding]; other site
882884000027	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
882884000028	putative binding surface; other site
882884000029	active site
882884000030	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
882884000031	TRAM domain; Region: TRAM; pfam01938
882884000032	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884000033	S-adenosylmethionine binding site [chemical binding]; other site
882884000034	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
882884000035	HD domain; Region: HD_4; pfam13328
882884000036	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
882884000037	synthetase active site [active]
882884000038	NTP binding site [chemical binding]; other site
882884000039	metal binding site [ion binding]; metal-binding site
882884000040	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
882884000041	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
882884000042	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
882884000043	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
882884000044	homodimer interface [polypeptide binding]; other site
882884000045	metal binding site [ion binding]; metal-binding site
882884000046	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
882884000047	homodimer interface [polypeptide binding]; other site
882884000048	active site
882884000049	putative chemical substrate binding site [chemical binding]; other site
882884000050	metal binding site [ion binding]; metal-binding site
882884000051	CTP synthetase; Validated; Region: pyrG; PRK05380
882884000052	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
882884000053	Catalytic site [active]
882884000054	active site
882884000055	UTP binding site [chemical binding]; other site
882884000056	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
882884000057	active site
882884000058	putative oxyanion hole; other site
882884000059	catalytic triad [active]
882884000060	enolase; Provisional; Region: eno; PRK00077
882884000061	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
882884000062	dimer interface [polypeptide binding]; other site
882884000063	metal binding site [ion binding]; metal-binding site
882884000064	substrate binding pocket [chemical binding]; other site
882884000065	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
882884000066	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
882884000067	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
882884000068	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
882884000069	active site
882884000070	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
882884000071	Flavodoxin; Region: Flavodoxin_1; pfam00258
882884000072	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
882884000073	FAD binding pocket [chemical binding]; other site
882884000074	FAD binding motif [chemical binding]; other site
882884000075	catalytic residues [active]
882884000076	NAD binding pocket [chemical binding]; other site
882884000077	phosphate binding motif [ion binding]; other site
882884000078	beta-alpha-beta structure motif; other site
882884000079	sulfite reductase subunit beta; Provisional; Region: PRK13504
882884000080	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
882884000081	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
882884000082	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
882884000083	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
882884000084	Active Sites [active]
882884000085	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
882884000086	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
882884000087	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
882884000088	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
882884000089	metal binding site [ion binding]; metal-binding site
882884000090	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
882884000091	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
882884000092	Active Sites [active]
882884000093	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
882884000094	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
882884000095	CysD dimerization site [polypeptide binding]; other site
882884000096	G1 box; other site
882884000097	putative GEF interaction site [polypeptide binding]; other site
882884000098	GTP/Mg2+ binding site [chemical binding]; other site
882884000099	Switch I region; other site
882884000100	G2 box; other site
882884000101	G3 box; other site
882884000102	Switch II region; other site
882884000103	G4 box; other site
882884000104	G5 box; other site
882884000105	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
882884000106	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
882884000107	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
882884000108	ligand-binding site [chemical binding]; other site
882884000109	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
882884000110	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
882884000111	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
882884000112	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
882884000113	substrate binding site; other site
882884000114	dimer interface; other site
882884000115	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
882884000116	homotrimer interaction site [polypeptide binding]; other site
882884000117	zinc binding site [ion binding]; other site
882884000118	CDP-binding sites; other site
882884000119	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
882884000120	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
882884000121	Permutation of conserved domain; other site
882884000122	active site
882884000123	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
882884000124	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
882884000125	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
882884000126	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884000127	S-adenosylmethionine binding site [chemical binding]; other site
882884000128	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
882884000129	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
882884000130	Peptidase family M23; Region: Peptidase_M23; pfam01551
882884000131	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
882884000132	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
882884000133	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
882884000134	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
882884000135	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
882884000136	DNA binding residues [nucleotide binding]
882884000137	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
882884000138	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
882884000139	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
882884000140	Flavoprotein; Region: Flavoprotein; pfam02441
882884000141	MarR family; Region: MarR_2; cl17246
882884000142	Transcriptional regulators [Transcription]; Region: MarR; COG1846
882884000143	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884000144	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884000145	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
882884000146	putative effector binding pocket; other site
882884000147	dimerization interface [polypeptide binding]; other site
882884000148	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884000149	Major Facilitator Superfamily; Region: MFS_1; pfam07690
882884000150	putative substrate translocation pore; other site
882884000151	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
882884000152	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
882884000153	MutS domain I; Region: MutS_I; pfam01624
882884000154	MutS domain II; Region: MutS_II; pfam05188
882884000155	MutS domain III; Region: MutS_III; pfam05192
882884000156	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
882884000157	Walker A/P-loop; other site
882884000158	ATP binding site [chemical binding]; other site
882884000159	Q-loop/lid; other site
882884000160	ABC transporter signature motif; other site
882884000161	Walker B; other site
882884000162	D-loop; other site
882884000163	H-loop/switch region; other site
882884000164	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
882884000165	Integrase core domain; Region: rve; pfam00665
882884000166	Integrase core domain; Region: rve_3; pfam13683
882884000167	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
882884000168	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; cl14901
882884000169	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
882884000170	multiple promoter invertase; Provisional; Region: mpi; PRK13413
882884000171	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
882884000172	catalytic residues [active]
882884000173	catalytic nucleophile [active]
882884000174	Presynaptic Site I dimer interface [polypeptide binding]; other site
882884000175	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
882884000176	Synaptic Flat tetramer interface [polypeptide binding]; other site
882884000177	Synaptic Site I dimer interface [polypeptide binding]; other site
882884000178	DNA binding site [nucleotide binding]
882884000179	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
882884000180	DNA-binding interface [nucleotide binding]; DNA binding site
882884000181	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
882884000182	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
882884000183	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
882884000184	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
882884000185	This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990
882884000186	Protein of unknown function (DUF3396); Region: DUF3396; pfam11876
882884000187	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
882884000188	DNA-binding interface [nucleotide binding]; DNA binding site
882884000189	Winged helix-turn helix; Region: HTH_29; pfam13551
882884000190	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
882884000191	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
882884000192	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
882884000193	active site flap/lid [active]
882884000194	nucleophilic elbow; other site
882884000195	catalytic triad [active]
882884000196	MbeB-like, N-term conserved region; Region: MbeB_N; pfam04837
882884000197	Transposase, Mutator family; Region: Transposase_mut; pfam00872
882884000198	Transposase; Region: DEDD_Tnp_IS110; pfam01548
882884000199	InvH outer membrane lipoprotein; Region: InvH; pfam04741
882884000200	transcriptional regulator InvF; Provisional; Region: PRK15340
882884000201	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
882884000202	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
882884000203	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
882884000204	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
882884000205	type III secretion system regulator InvE; Provisional; Region: PRK15338
882884000206	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
882884000207	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
882884000208	type III secretion system protein InvA; Provisional; Region: PRK15337
882884000209	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
882884000210	ATP synthase SpaL; Validated; Region: PRK08149
882884000211	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
882884000212	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
882884000213	Walker A motif; other site
882884000214	ATP binding site [chemical binding]; other site
882884000215	Walker B motif; other site
882884000216	type III secretion system protein SpaM; Provisional; Region: PRK15335
882884000217	antigen presentation protein SpaN; Provisional; Region: PRK15334
882884000218	Surface presentation of antigens protein; Region: SPAN; pfam02510
882884000219	type III secretion system protein SpaO; Validated; Region: PRK08158
882884000220	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
882884000221	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
882884000222	type III secretion system protein SpaQ; Provisional; Region: PRK15333
882884000223	type III secretion system protein SpaR; Provisional; Region: PRK15332
882884000224	type III secretion system protein SpaS; Validated; Region: PRK08156
882884000225	chaperone protein SicA; Provisional; Region: PRK15331
882884000226	Tetratricopeptide repeat; Region: TPR_3; pfam07720
882884000227	Tetratricopeptide repeat; Region: TPR_3; pfam07720
882884000228	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
882884000229	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
882884000230	cell invasion protein SipD; Provisional; Region: PRK15330
882884000231	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
882884000232	putative acyl carrier protein IacP; Validated; Region: PRK08172
882884000233	chaperone protein SicP; Provisional; Region: PRK15329
882884000234	SicP binding; Region: SicP-binding; pfam09119
882884000235	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
882884000236	switch II binding region; other site
882884000237	Rac1 P-loop interaction site [polypeptide binding]; other site
882884000238	GTP binding residues [chemical binding]; other site
882884000239	switch I binding region; other site
882884000240	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
882884000241	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
882884000242	N-acetyl-D-glucosamine binding site [chemical binding]; other site
882884000243	catalytic residue [active]
882884000244	invasion protein regulator; Provisional; Region: PRK12370
882884000245	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884000246	DNA binding site [nucleotide binding]
882884000247	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
882884000248	binding surface
882884000249	TPR motif; other site
882884000250	transcriptional regulator HilD; Provisional; Region: PRK15185
882884000251	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884000252	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
882884000253	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
882884000254	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
882884000255	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
882884000256	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
882884000257	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
882884000258	invasion protein OrgA; Provisional; Region: PRK15323
882884000259	invasion protein OrgB; Provisional; Region: PRK15322
882884000260	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
882884000261	transcriptional regulator SirC; Provisional; Region: PRK15044
882884000262	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884000263	transcriptional activator SprB; Provisional; Region: PRK15320
882884000264	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
882884000265	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
882884000266	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
882884000267	ABC-ATPase subunit  interface; other site
882884000268	dimer interface [polypeptide binding]; other site
882884000269	putative PBP binding regions; other site
882884000270	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
882884000271	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
882884000272	ABC-ATPase subunit  interface; other site
882884000273	dimer interface [polypeptide binding]; other site
882884000274	putative PBP binding regions; other site
882884000275	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
882884000276	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
882884000277	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
882884000278	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
882884000279	metal binding site [ion binding]; metal-binding site
882884000280	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
882884000281	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
882884000282	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
882884000283	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
882884000284	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884000285	Walker A motif; other site
882884000286	ATP binding site [chemical binding]; other site
882884000287	Walker B motif; other site
882884000288	arginine finger; other site
882884000289	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
882884000290	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
882884000291	dimerization interface [polypeptide binding]; other site
882884000292	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
882884000293	ATP binding site [chemical binding]; other site
882884000294	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
882884000295	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
882884000296	hydrogenase assembly chaperone; Provisional; Region: PRK10409
882884000297	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
882884000298	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
882884000299	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
882884000300	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
882884000301	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
882884000302	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
882884000303	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
882884000304	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
882884000305	NADH dehydrogenase; Region: NADHdh; cl00469
882884000306	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
882884000307	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
882884000308	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
882884000309	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
882884000310	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
882884000311	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
882884000312	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
882884000313	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
882884000314	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
882884000315	nickel binding site [ion binding]; other site
882884000316	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
882884000317	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
882884000318	Acylphosphatase; Region: Acylphosphatase; pfam00708
882884000319	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
882884000320	HypF finger; Region: zf-HYPF; pfam07503
882884000321	HypF finger; Region: zf-HYPF; pfam07503
882884000322	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
882884000323	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
882884000324	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
882884000325	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884000326	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
882884000327	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
882884000328	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
882884000329	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
882884000330	iron binding site [ion binding]; other site
882884000331	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
882884000332	GAF domain; Region: GAF; pfam01590
882884000333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884000334	Walker A motif; other site
882884000335	ATP binding site [chemical binding]; other site
882884000336	Walker B motif; other site
882884000337	arginine finger; other site
882884000338	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
882884000339	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
882884000340	putative active site [active]
882884000341	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
882884000342	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
882884000343	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
882884000344	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884000345	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
882884000346	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
882884000347	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
882884000348	putative NAD(P) binding site [chemical binding]; other site
882884000349	active site
882884000350	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
882884000351	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
882884000352	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
882884000353	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
882884000354	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
882884000355	Transglycosylase SLT domain; Region: SLT_2; pfam13406
882884000356	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
882884000357	N-acetyl-D-glucosamine binding site [chemical binding]; other site
882884000358	catalytic residue [active]
882884000359	hypothetical protein; Validated; Region: PRK03661
882884000360	recombinase A; Provisional; Region: recA; PRK09354
882884000361	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
882884000362	hexamer interface [polypeptide binding]; other site
882884000363	Walker A motif; other site
882884000364	ATP binding site [chemical binding]; other site
882884000365	Walker B motif; other site
882884000366	recombination regulator RecX; Reviewed; Region: recX; PRK00117
882884000367	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
882884000368	Walker A motif; other site
882884000369	ATP binding site [chemical binding]; other site
882884000370	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
882884000371	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
882884000372	motif 1; other site
882884000373	active site
882884000374	motif 2; other site
882884000375	motif 3; other site
882884000376	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
882884000377	DHHA1 domain; Region: DHHA1; pfam02272
882884000378	carbon storage regulator; Provisional; Region: PRK01712
882884000379	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
882884000380	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884000381	motif II; other site
882884000382	Predicted membrane protein [Function unknown]; Region: COG1238
882884000383	glutamate--cysteine ligase; Provisional; Region: PRK02107
882884000384	S-ribosylhomocysteinase; Provisional; Region: PRK02260
882884000385	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
882884000386	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884000387	putative substrate translocation pore; other site
882884000388	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884000389	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
882884000390	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
882884000391	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884000392	transcriptional repressor MprA; Provisional; Region: PRK10870
882884000393	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
882884000394	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
882884000395	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884000396	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
882884000397	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
882884000398	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
882884000399	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884000400	dimer interface [polypeptide binding]; other site
882884000401	conserved gate region; other site
882884000402	putative PBP binding loops; other site
882884000403	ABC-ATPase subunit interface; other site
882884000404	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
882884000405	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
882884000406	Walker A/P-loop; other site
882884000407	ATP binding site [chemical binding]; other site
882884000408	Q-loop/lid; other site
882884000409	ABC transporter signature motif; other site
882884000410	Walker B; other site
882884000411	D-loop; other site
882884000412	H-loop/switch region; other site
882884000413	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
882884000414	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
882884000415	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
882884000416	dimer interface [polypeptide binding]; other site
882884000417	putative radical transfer pathway; other site
882884000418	diiron center [ion binding]; other site
882884000419	tyrosyl radical; other site
882884000420	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
882884000421	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
882884000422	Class I ribonucleotide reductase; Region: RNR_I; cd01679
882884000423	active site
882884000424	dimer interface [polypeptide binding]; other site
882884000425	catalytic residues [active]
882884000426	effector binding site; other site
882884000427	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
882884000428	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
882884000429	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
882884000430	catalytic residues [active]
882884000431	hypothetical protein; Provisional; Region: PRK10132
882884000432	hypothetical protein; Provisional; Region: PRK10556
882884000433	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
882884000434	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
882884000435	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
882884000436	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
882884000437	active site residue [active]
882884000438	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
882884000439	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
882884000440	putative DNA binding site [nucleotide binding]; other site
882884000441	putative Zn2+ binding site [ion binding]; other site
882884000442	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
882884000443	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
882884000444	bacterial OsmY and nodulation domain; Region: BON; smart00749
882884000445	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
882884000446	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
882884000447	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884000448	DNA-binding site [nucleotide binding]; DNA binding site
882884000449	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
882884000450	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
882884000451	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
882884000452	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
882884000453	inhibitor-cofactor binding pocket; inhibition site
882884000454	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884000455	catalytic residue [active]
882884000456	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
882884000457	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
882884000458	tetramerization interface [polypeptide binding]; other site
882884000459	NAD(P) binding site [chemical binding]; other site
882884000460	catalytic residues [active]
882884000461	Predicted dehydrogenase [General function prediction only]; Region: COG0579
882884000462	hydroxyglutarate oxidase; Provisional; Region: PRK11728
882884000463	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
882884000464	substrate binding pocket [chemical binding]; other site
882884000465	active site
882884000466	iron coordination sites [ion binding]; other site
882884000467	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
882884000468	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
882884000469	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
882884000470	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
882884000471	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884000472	active site
882884000473	phosphorylation site [posttranslational modification]
882884000474	intermolecular recognition site; other site
882884000475	dimerization interface [polypeptide binding]; other site
882884000476	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884000477	DNA binding site [nucleotide binding]
882884000478	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
882884000479	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
882884000480	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
882884000481	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884000482	dimer interface [polypeptide binding]; other site
882884000483	phosphorylation site [posttranslational modification]
882884000484	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884000485	ATP binding site [chemical binding]; other site
882884000486	Mg2+ binding site [ion binding]; other site
882884000487	G-X-G motif; other site
882884000488	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
882884000489	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
882884000490	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
882884000491	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
882884000492	secreted effector protein PipB2; Provisional; Region: PRK15196
882884000493	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
882884000494	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
882884000495	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
882884000496	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
882884000497	outer membrane receptor FepA; Provisional; Region: PRK13528
882884000498	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
882884000499	N-terminal plug; other site
882884000500	ligand-binding site [chemical binding]; other site
882884000501	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
882884000502	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
882884000503	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
882884000504	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
882884000505	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884000506	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
882884000507	Walker A/P-loop; other site
882884000508	ATP binding site [chemical binding]; other site
882884000509	Q-loop/lid; other site
882884000510	ABC transporter signature motif; other site
882884000511	Walker B; other site
882884000512	D-loop; other site
882884000513	H-loop/switch region; other site
882884000514	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
882884000515	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
882884000516	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884000517	Walker A/P-loop; other site
882884000518	ATP binding site [chemical binding]; other site
882884000519	Q-loop/lid; other site
882884000520	ABC transporter signature motif; other site
882884000521	Walker B; other site
882884000522	D-loop; other site
882884000523	H-loop/switch region; other site
882884000524	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
882884000525	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
882884000526	homodimer interface [polypeptide binding]; other site
882884000527	active site
882884000528	TDP-binding site; other site
882884000529	acceptor substrate-binding pocket; other site
882884000530	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
882884000531	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
882884000532	catalytic nucleophile [active]
882884000533	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
882884000534	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
882884000535	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
882884000536	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
882884000537	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
882884000538	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
882884000539	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
882884000540	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
882884000541	active site
882884000542	Int/Topo IB signature motif; other site
882884000543	catalytic residues [active]
882884000544	DNA binding site [nucleotide binding]
882884000545	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
882884000546	active site
882884000547	catalytic residues [active]
882884000548	DNA binding site [nucleotide binding]
882884000549	Int/Topo IB signature motif; other site
882884000550	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4688
882884000551	lipoprotein NlpI; Provisional; Region: PRK11189
882884000552	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
882884000553	DEAD-like helicases superfamily; Region: DEXDc; smart00487
882884000554	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884000555	ATP binding site [chemical binding]; other site
882884000556	putative Mg++ binding site [ion binding]; other site
882884000557	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
882884000558	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
882884000559	active site
882884000560	nucleophile elbow; other site
882884000561	ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2; Region: Pat_ExoU_VipD_like; cd07207
882884000562	integrase; Provisional; Region: PRK09692
882884000563	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
882884000564	active site
882884000565	Int/Topo IB signature motif; other site
882884000566	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
882884000567	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884000568	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
882884000569	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
882884000570	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884000571	Walker A/P-loop; other site
882884000572	ATP binding site [chemical binding]; other site
882884000573	Q-loop/lid; other site
882884000574	ABC transporter signature motif; other site
882884000575	Walker B; other site
882884000576	D-loop; other site
882884000577	H-loop/switch region; other site
882884000578	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
882884000579	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000580	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000581	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000582	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000583	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000584	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000585	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000586	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000587	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000588	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000589	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000590	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884000591	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000592	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884000593	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
882884000594	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
882884000595	SmpB-tmRNA interface; other site
882884000596	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
882884000597	putative coenzyme Q binding site [chemical binding]; other site
882884000598	hypothetical protein; Validated; Region: PRK01777
882884000599	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
882884000600	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
882884000601	recombination and repair protein; Provisional; Region: PRK10869
882884000602	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
882884000603	Walker A/P-loop; other site
882884000604	ATP binding site [chemical binding]; other site
882884000605	Q-loop/lid; other site
882884000606	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
882884000607	ABC transporter signature motif; other site
882884000608	Walker B; other site
882884000609	D-loop; other site
882884000610	H-loop/switch region; other site
882884000611	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
882884000612	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
882884000613	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
882884000614	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
882884000615	dimer interface [polypeptide binding]; other site
882884000616	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
882884000617	hypothetical protein; Provisional; Region: PRK11573
882884000618	Domain of unknown function DUF21; Region: DUF21; pfam01595
882884000619	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
882884000620	Transporter associated domain; Region: CorC_HlyC; smart01091
882884000621	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
882884000622	signal recognition particle protein; Provisional; Region: PRK10867
882884000623	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
882884000624	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
882884000625	P loop; other site
882884000626	GTP binding site [chemical binding]; other site
882884000627	Signal peptide binding domain; Region: SRP_SPB; pfam02978
882884000628	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
882884000629	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
882884000630	RimM N-terminal domain; Region: RimM; pfam01782
882884000631	PRC-barrel domain; Region: PRC; pfam05239
882884000632	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
882884000633	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
882884000634	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
882884000635	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
882884000636	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
882884000637	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
882884000638	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
882884000639	Chorismate mutase type II; Region: CM_2; cl00693
882884000640	prephenate dehydrogenase; Validated; Region: PRK08507
882884000641	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
882884000642	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
882884000643	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
882884000644	Prephenate dehydratase; Region: PDT; pfam00800
882884000645	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
882884000646	putative L-Phe binding site [chemical binding]; other site
882884000647	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
882884000648	30S subunit binding site; other site
882884000649	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
882884000650	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
882884000651	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
882884000652	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
882884000653	RNA binding surface [nucleotide binding]; other site
882884000654	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
882884000655	active site
882884000656	hypothetical protein; Provisional; Region: PRK10723
882884000657	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
882884000658	protein disaggregation chaperone; Provisional; Region: PRK10865
882884000659	Clp amino terminal domain; Region: Clp_N; pfam02861
882884000660	Clp amino terminal domain; Region: Clp_N; pfam02861
882884000661	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884000662	Walker A motif; other site
882884000663	ATP binding site [chemical binding]; other site
882884000664	Walker B motif; other site
882884000665	arginine finger; other site
882884000666	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884000667	Walker A motif; other site
882884000668	ATP binding site [chemical binding]; other site
882884000669	Walker B motif; other site
882884000670	arginine finger; other site
882884000671	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
882884000672	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
882884000673	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
882884000674	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884000675	putative substrate translocation pore; other site
882884000676	lipoprotein; Provisional; Region: PRK10759
882884000677	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
882884000678	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
882884000679	domain interface [polypeptide binding]; other site
882884000680	putative active site [active]
882884000681	catalytic site [active]
882884000682	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
882884000683	domain interface [polypeptide binding]; other site
882884000684	putative active site [active]
882884000685	catalytic site [active]
882884000686	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
882884000687	CoA binding domain; Region: CoA_binding_2; pfam13380
882884000688	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
882884000689	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
882884000690	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
882884000691	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884000692	Coenzyme A binding pocket [chemical binding]; other site
882884000693	Uncharacterized conserved protein [Function unknown]; Region: COG3148
882884000694	thioredoxin 2; Provisional; Region: PRK10996
882884000695	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
882884000696	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
882884000697	catalytic residues [active]
882884000698	putative methyltransferase; Provisional; Region: PRK10864
882884000699	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
882884000700	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
882884000701	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
882884000702	ligand binding site [chemical binding]; other site
882884000703	active site
882884000704	UGI interface [polypeptide binding]; other site
882884000705	catalytic site [active]
882884000706	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
882884000707	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
882884000708	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
882884000709	ATP binding site [chemical binding]; other site
882884000710	Mg++ binding site [ion binding]; other site
882884000711	motif III; other site
882884000712	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884000713	nucleotide binding region [chemical binding]; other site
882884000714	ATP-binding site [chemical binding]; other site
882884000715	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
882884000716	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884000717	S-adenosylmethionine binding site [chemical binding]; other site
882884000718	L-aspartate oxidase; Provisional; Region: PRK09077
882884000719	L-aspartate oxidase; Provisional; Region: PRK06175
882884000720	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
882884000721	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
882884000722	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
882884000723	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
882884000724	DNA binding residues [nucleotide binding]
882884000725	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
882884000726	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
882884000727	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
882884000728	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
882884000729	anti-sigma E factor; Provisional; Region: rseB; PRK09455
882884000730	SoxR reducing system protein RseC; Provisional; Region: PRK10862
882884000731	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
882884000732	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
882884000733	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
882884000734	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
882884000735	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
882884000736	GTP-binding protein LepA; Provisional; Region: PRK05433
882884000737	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
882884000738	G1 box; other site
882884000739	putative GEF interaction site [polypeptide binding]; other site
882884000740	GTP/Mg2+ binding site [chemical binding]; other site
882884000741	Switch I region; other site
882884000742	G2 box; other site
882884000743	G3 box; other site
882884000744	Switch II region; other site
882884000745	G4 box; other site
882884000746	G5 box; other site
882884000747	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
882884000748	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
882884000749	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
882884000750	signal peptidase I; Provisional; Region: PRK10861
882884000751	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
882884000752	Catalytic site [active]
882884000753	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
882884000754	rncO; Rfam score 223.8; SARI_00297
882884000755	GTPase Era; Reviewed; Region: era; PRK00089
882884000756	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
882884000757	G1 box; other site
882884000758	GTP/Mg2+ binding site [chemical binding]; other site
882884000759	Switch I region; other site
882884000760	G2 box; other site
882884000761	Switch II region; other site
882884000762	G3 box; other site
882884000763	G4 box; other site
882884000764	G5 box; other site
882884000765	KH domain; Region: KH_2; pfam07650
882884000766	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
882884000767	Recombination protein O N terminal; Region: RecO_N; pfam11967
882884000768	Recombination protein O C terminal; Region: RecO_C; pfam02565
882884000769	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
882884000770	active site
882884000771	hydrophilic channel; other site
882884000772	dimerization interface [polypeptide binding]; other site
882884000773	catalytic residues [active]
882884000774	active site lid [active]
882884000775	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
882884000776	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
882884000777	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
882884000778	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
882884000779	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
882884000780	putative active site [active]
882884000781	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
882884000782	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
882884000783	putative active site [active]
882884000784	hypothetical protein; Provisional; Region: PRK11590
882884000785	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
882884000786	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
882884000787	nucleoside/Zn binding site; other site
882884000788	dimer interface [polypeptide binding]; other site
882884000789	catalytic motif [active]
882884000790	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
882884000791	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884000792	substrate binding pocket [chemical binding]; other site
882884000793	membrane-bound complex binding site; other site
882884000794	hinge residues; other site
882884000795	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
882884000796	N-acetyl-D-glucosamine binding site [chemical binding]; other site
882884000797	catalytic residue [active]
882884000798	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
882884000799	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
882884000800	dimerization interface [polypeptide binding]; other site
882884000801	ATP binding site [chemical binding]; other site
882884000802	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
882884000803	dimerization interface [polypeptide binding]; other site
882884000804	ATP binding site [chemical binding]; other site
882884000805	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
882884000806	putative active site [active]
882884000807	catalytic triad [active]
882884000808	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
882884000809	HAMP domain; Region: HAMP; pfam00672
882884000810	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884000811	dimer interface [polypeptide binding]; other site
882884000812	phosphorylation site [posttranslational modification]
882884000813	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884000814	ATP binding site [chemical binding]; other site
882884000815	Mg2+ binding site [ion binding]; other site
882884000816	G-X-G motif; other site
882884000817	hypothetical protein; Provisional; Region: PRK10722
882884000818	response regulator GlrR; Provisional; Region: PRK15115
882884000819	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884000820	active site
882884000821	phosphorylation site [posttranslational modification]
882884000822	intermolecular recognition site; other site
882884000823	dimerization interface [polypeptide binding]; other site
882884000824	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884000825	Walker A motif; other site
882884000826	ATP binding site [chemical binding]; other site
882884000827	Walker B motif; other site
882884000828	arginine finger; other site
882884000829	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
882884000830	Nitrogen regulatory protein P-II; Region: P-II; smart00938
882884000831	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
882884000832	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884000833	putative substrate translocation pore; other site
882884000834	POT family; Region: PTR2; pfam00854
882884000835	lysine decarboxylase CadA; Provisional; Region: PRK15400
882884000836	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
882884000837	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
882884000838	homodimer interface [polypeptide binding]; other site
882884000839	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884000840	catalytic residue [active]
882884000841	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
882884000842	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
882884000843	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
882884000844	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884000845	DNA binding site [nucleotide binding]
882884000846	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
882884000847	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
882884000848	heme-binding site [chemical binding]; other site
882884000849	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
882884000850	FAD binding pocket [chemical binding]; other site
882884000851	FAD binding motif [chemical binding]; other site
882884000852	phosphate binding motif [ion binding]; other site
882884000853	beta-alpha-beta structure motif; other site
882884000854	NAD binding pocket [chemical binding]; other site
882884000855	Heme binding  pocket [chemical binding]; other site
882884000856	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
882884000857	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
882884000858	dimer interface [polypeptide binding]; other site
882884000859	active site
882884000860	glycine-pyridoxal phosphate binding site [chemical binding]; other site
882884000861	folate binding site [chemical binding]; other site
882884000862	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
882884000863	MFS_1 like family; Region: MFS_1_like; pfam12832
882884000864	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
882884000865	PRD domain; Region: PRD; pfam00874
882884000866	PRD domain; Region: PRD; pfam00874
882884000867	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
882884000868	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
882884000869	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
882884000870	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
882884000871	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
882884000872	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
882884000873	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
882884000874	FAD binding pocket [chemical binding]; other site
882884000875	FAD binding motif [chemical binding]; other site
882884000876	phosphate binding motif [ion binding]; other site
882884000877	beta-alpha-beta structure motif; other site
882884000878	NAD binding pocket [chemical binding]; other site
882884000879	Iron coordination center [ion binding]; other site
882884000880	anaerobic sulfite reductase subunit A; Provisional; Region: PRK15055
882884000881	The Death Domain Superfamily of protein-protein interaction domains; Region: DD_superfamily; cl14633
882884000882	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
882884000883	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
882884000884	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
882884000885	active site
882884000886	dimerization interface [polypeptide binding]; other site
882884000887	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
882884000888	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
882884000889	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
882884000890	Rrf2 family protein; Region: rrf2_super; TIGR00738
882884000891	cysteine desulfurase; Provisional; Region: PRK14012
882884000892	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
882884000893	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
882884000894	catalytic residue [active]
882884000895	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
882884000896	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
882884000897	trimerization site [polypeptide binding]; other site
882884000898	active site
882884000899	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
882884000900	co-chaperone HscB; Provisional; Region: hscB; PRK05014
882884000901	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
882884000902	HSP70 interaction site [polypeptide binding]; other site
882884000903	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
882884000904	chaperone protein HscA; Provisional; Region: hscA; PRK05183
882884000905	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
882884000906	nucleotide binding site [chemical binding]; other site
882884000907	putative NEF/HSP70 interaction site [polypeptide binding]; other site
882884000908	SBD interface [polypeptide binding]; other site
882884000909	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
882884000910	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
882884000911	catalytic loop [active]
882884000912	iron binding site [ion binding]; other site
882884000913	hypothetical protein; Provisional; Region: PRK10721
882884000914	aminopeptidase B; Provisional; Region: PRK05015
882884000915	Peptidase; Region: DUF3663; pfam12404
882884000916	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
882884000917	interface (dimer of trimers) [polypeptide binding]; other site
882884000918	Substrate-binding/catalytic site; other site
882884000919	Zn-binding sites [ion binding]; other site
882884000920	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
882884000921	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
882884000922	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
882884000923	active site residue [active]
882884000924	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
882884000925	active site residue [active]
882884000926	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
882884000927	MG2 domain; Region: A2M_N; pfam01835
882884000928	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
882884000929	surface patch; other site
882884000930	thioester region; other site
882884000931	specificity defining residues; other site
882884000932	penicillin-binding protein 1C; Provisional; Region: PRK11240
882884000933	Transglycosylase; Region: Transgly; pfam00912
882884000934	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
882884000935	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
882884000936	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
882884000937	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
882884000938	putative [Fe4-S4] binding site [ion binding]; other site
882884000939	putative molybdopterin cofactor binding site [chemical binding]; other site
882884000940	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
882884000941	putative molybdopterin cofactor binding site; other site
882884000942	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
882884000943	4Fe-4S binding domain; Region: Fer4; pfam00037
882884000944	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
882884000945	4Fe-4S binding domain; Region: Fer4; pfam00037
882884000946	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
882884000947	active site
882884000948	multimer interface [polypeptide binding]; other site
882884000949	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
882884000950	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884000951	FeS/SAM binding site; other site
882884000952	cytoskeletal protein RodZ; Provisional; Region: PRK10856
882884000953	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884000954	non-specific DNA binding site [nucleotide binding]; other site
882884000955	salt bridge; other site
882884000956	sequence-specific DNA binding site [nucleotide binding]; other site
882884000957	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
882884000958	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
882884000959	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
882884000960	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
882884000961	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
882884000962	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
882884000963	dimer interface [polypeptide binding]; other site
882884000964	motif 1; other site
882884000965	active site
882884000966	motif 2; other site
882884000967	motif 3; other site
882884000968	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
882884000969	anticodon binding site; other site
882884000970	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
882884000971	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
882884000972	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
882884000973	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
882884000974	Trp docking motif [polypeptide binding]; other site
882884000975	GTP-binding protein Der; Reviewed; Region: PRK00093
882884000976	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
882884000977	G1 box; other site
882884000978	GTP/Mg2+ binding site [chemical binding]; other site
882884000979	Switch I region; other site
882884000980	G2 box; other site
882884000981	Switch II region; other site
882884000982	G3 box; other site
882884000983	G4 box; other site
882884000984	G5 box; other site
882884000985	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
882884000986	G1 box; other site
882884000987	GTP/Mg2+ binding site [chemical binding]; other site
882884000988	Switch I region; other site
882884000989	G2 box; other site
882884000990	G3 box; other site
882884000991	Switch II region; other site
882884000992	G4 box; other site
882884000993	G5 box; other site
882884000994	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
882884000995	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
882884000996	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
882884000997	active site
882884000998	Zn binding site [ion binding]; other site
882884000999	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
882884001000	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
882884001001	generic binding surface II; other site
882884001002	generic binding surface I; other site
882884001003	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
882884001004	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
882884001005	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
882884001006	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
882884001007	active site
882884001008	GMP synthase; Reviewed; Region: guaA; PRK00074
882884001009	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
882884001010	AMP/PPi binding site [chemical binding]; other site
882884001011	candidate oxyanion hole; other site
882884001012	catalytic triad [active]
882884001013	potential glutamine specificity residues [chemical binding]; other site
882884001014	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
882884001015	ATP Binding subdomain [chemical binding]; other site
882884001016	Ligand Binding sites [chemical binding]; other site
882884001017	Dimerization subdomain; other site
882884001018	Homeodomain-like domain; Region: HTH_23; pfam13384
882884001019	Winged helix-turn helix; Region: HTH_29; pfam13551
882884001020	Winged helix-turn helix; Region: HTH_33; pfam13592
882884001021	DDE superfamily endonuclease; Region: DDE_3; pfam13358
882884001022	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
882884001023	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
882884001024	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
882884001025	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
882884001026	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
882884001027	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
882884001028	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
882884001029	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
882884001030	Sel1 repeat; Region: Sel1; cl02723
882884001031	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
882884001032	MASE1; Region: MASE1; pfam05231
882884001033	diguanylate cyclase; Region: GGDEF; smart00267
882884001034	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
882884001035	exopolyphosphatase; Provisional; Region: PRK10854
882884001036	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
882884001037	nucleotide binding site [chemical binding]; other site
882884001038	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
882884001039	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
882884001040	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
882884001041	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
882884001042	putative active site [active]
882884001043	catalytic site [active]
882884001044	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
882884001045	domain interface [polypeptide binding]; other site
882884001046	active site
882884001047	catalytic site [active]
882884001048	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
882884001049	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
882884001050	active site
882884001051	substrate binding site [chemical binding]; other site
882884001052	cosubstrate binding site; other site
882884001053	catalytic site [active]
882884001054	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
882884001055	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
882884001056	dimerization interface [polypeptide binding]; other site
882884001057	putative ATP binding site [chemical binding]; other site
882884001058	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
882884001059	active site
882884001060	uracil transporter; Provisional; Region: PRK10720
882884001061	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
882884001062	DNA replication initiation factor; Provisional; Region: PRK08084
882884001063	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
882884001064	ArsC family; Region: ArsC; pfam03960
882884001065	catalytic residues [active]
882884001066	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
882884001067	Peptidase family M48; Region: Peptidase_M48; cl12018
882884001068	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
882884001069	Domain of unknown function DUF20; Region: UPF0118; pfam01594
882884001070	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
882884001071	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
882884001072	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
882884001073	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
882884001074	fructuronate transporter; Provisional; Region: PRK10034; cl15264
882884001075	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
882884001076	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
882884001077	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
882884001078	catalytic triad [active]
882884001079	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
882884001080	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
882884001081	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
882884001082	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
882884001083	dihydrodipicolinate synthase; Region: dapA; TIGR00674
882884001084	dimer interface [polypeptide binding]; other site
882884001085	active site
882884001086	catalytic residue [active]
882884001087	lipoprotein; Provisional; Region: PRK11679
882884001088	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
882884001089	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
882884001090	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
882884001091	ATP binding site [chemical binding]; other site
882884001092	active site
882884001093	substrate binding site [chemical binding]; other site
882884001094	Predicted metalloprotease [General function prediction only]; Region: COG2321
882884001095	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
882884001096	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
882884001097	Helicase; Region: Helicase_RecD; pfam05127
882884001098	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
882884001099	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
882884001100	hypothetical protein; Provisional; Region: PRK13664
882884001101	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
882884001102	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
882884001103	metal binding site [ion binding]; metal-binding site
882884001104	dimer interface [polypeptide binding]; other site
882884001105	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
882884001106	ArsC family; Region: ArsC; pfam03960
882884001107	putative catalytic residues [active]
882884001108	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
882884001109	Protein export membrane protein; Region: SecD_SecF; cl14618
882884001110	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
882884001111	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
882884001112	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884001113	dimerization interface [polypeptide binding]; other site
882884001114	Histidine kinase; Region: HisKA_3; pfam07730
882884001115	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884001116	ATP binding site [chemical binding]; other site
882884001117	Mg2+ binding site [ion binding]; other site
882884001118	G-X-G motif; other site
882884001119	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
882884001120	4Fe-4S binding domain; Region: Fer4; pfam00037
882884001121	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
882884001122	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884001123	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
882884001124	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
882884001125	dimer interface [polypeptide binding]; other site
882884001126	ADP-ribose binding site [chemical binding]; other site
882884001127	active site
882884001128	nudix motif; other site
882884001129	metal binding site [ion binding]; metal-binding site
882884001130	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
882884001131	transketolase; Reviewed; Region: PRK12753
882884001132	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
882884001133	TPP-binding site [chemical binding]; other site
882884001134	dimer interface [polypeptide binding]; other site
882884001135	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
882884001136	PYR/PP interface [polypeptide binding]; other site
882884001137	dimer interface [polypeptide binding]; other site
882884001138	TPP binding site [chemical binding]; other site
882884001139	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
882884001140	transaldolase-like protein; Provisional; Region: PTZ00411
882884001141	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
882884001142	active site
882884001143	dimer interface [polypeptide binding]; other site
882884001144	catalytic residue [active]
882884001145	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
882884001146	Malic enzyme, N-terminal domain; Region: malic; pfam00390
882884001147	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
882884001148	putative NAD(P) binding site [chemical binding]; other site
882884001149	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
882884001150	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884001151	Sulfatase; Region: Sulfatase; pfam00884
882884001152	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
882884001153	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884001154	FeS/SAM binding site; other site
882884001155	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
882884001156	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
882884001157	putative hexamer interface [polypeptide binding]; other site
882884001158	putative hexagonal pore; other site
882884001159	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
882884001160	G1 box; other site
882884001161	GTP/Mg2+ binding site [chemical binding]; other site
882884001162	G2 box; other site
882884001163	Switch I region; other site
882884001164	G3 box; other site
882884001165	Switch II region; other site
882884001166	G4 box; other site
882884001167	G5 box; other site
882884001168	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
882884001169	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
882884001170	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
882884001171	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
882884001172	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
882884001173	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
882884001174	Hexamer interface [polypeptide binding]; other site
882884001175	Hexagonal pore residue; other site
882884001176	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
882884001177	Hexamer/Pentamer interface [polypeptide binding]; other site
882884001178	central pore; other site
882884001179	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
882884001180	putative catalytic cysteine [active]
882884001181	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
882884001182	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
882884001183	nucleotide binding site [chemical binding]; other site
882884001184	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
882884001185	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
882884001186	active site
882884001187	metal binding site [ion binding]; metal-binding site
882884001188	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
882884001189	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
882884001190	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
882884001191	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
882884001192	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
882884001193	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
882884001194	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
882884001195	putative hexamer interface [polypeptide binding]; other site
882884001196	putative hexagonal pore; other site
882884001197	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
882884001198	putative hexamer interface [polypeptide binding]; other site
882884001199	putative hexagonal pore; other site
882884001200	carboxysome structural protein EutK; Provisional; Region: PRK15466
882884001201	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
882884001202	Hexamer interface [polypeptide binding]; other site
882884001203	Hexagonal pore residue; other site
882884001204	transcriptional regulator EutR; Provisional; Region: PRK10130
882884001205	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884001206	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884001207	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
882884001208	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
882884001209	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
882884001210	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
882884001211	active site
882884001212	metal binding site [ion binding]; metal-binding site
882884001213	putative acetyltransferase; Provisional; Region: PRK03624
882884001214	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884001215	Coenzyme A binding pocket [chemical binding]; other site
882884001216	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
882884001217	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
882884001218	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
882884001219	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
882884001220	putative periplasmic esterase; Provisional; Region: PRK03642
882884001221	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
882884001222	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
882884001223	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
882884001224	active site turn [active]
882884001225	phosphorylation site [posttranslational modification]
882884001226	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
882884001227	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
882884001228	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
882884001229	putative active site [active]
882884001230	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; pfam09829
882884001231	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
882884001232	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
882884001233	trimer interface [polypeptide binding]; other site
882884001234	eyelet of channel; other site
882884001235	transcriptional regulator MurR; Provisional; Region: PRK15482
882884001236	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
882884001237	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
882884001238	putative active site [active]
882884001239	short chain dehydrogenase; Provisional; Region: PRK08226
882884001240	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
882884001241	NAD binding site [chemical binding]; other site
882884001242	homotetramer interface [polypeptide binding]; other site
882884001243	homodimer interface [polypeptide binding]; other site
882884001244	active site
882884001245	thiosulfate transporter subunit; Provisional; Region: PRK10852
882884001246	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
882884001247	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
882884001248	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884001249	dimer interface [polypeptide binding]; other site
882884001250	conserved gate region; other site
882884001251	putative PBP binding loops; other site
882884001252	ABC-ATPase subunit interface; other site
882884001253	sulfate transport protein; Provisional; Region: cysT; CHL00187
882884001254	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884001255	dimer interface [polypeptide binding]; other site
882884001256	conserved gate region; other site
882884001257	putative PBP binding loops; other site
882884001258	ABC-ATPase subunit interface; other site
882884001259	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
882884001260	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
882884001261	Walker A/P-loop; other site
882884001262	ATP binding site [chemical binding]; other site
882884001263	Q-loop/lid; other site
882884001264	ABC transporter signature motif; other site
882884001265	Walker B; other site
882884001266	D-loop; other site
882884001267	H-loop/switch region; other site
882884001268	TOBE-like domain; Region: TOBE_3; pfam12857
882884001269	cysteine synthase B; Region: cysM; TIGR01138
882884001270	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
882884001271	dimer interface [polypeptide binding]; other site
882884001272	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884001273	catalytic residue [active]
882884001274	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
882884001275	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
882884001276	catalytic triad [active]
882884001277	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
882884001278	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884001279	DNA-binding site [nucleotide binding]; DNA binding site
882884001280	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884001281	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884001282	homodimer interface [polypeptide binding]; other site
882884001283	catalytic residue [active]
882884001284	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
882884001285	dimer interface [polypeptide binding]; other site
882884001286	pyridoxamine kinase; Validated; Region: PRK05756
882884001287	pyridoxal binding site [chemical binding]; other site
882884001288	ATP binding site [chemical binding]; other site
882884001289	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
882884001290	HPr interaction site; other site
882884001291	glycerol kinase (GK) interaction site [polypeptide binding]; other site
882884001292	active site
882884001293	phosphorylation site [posttranslational modification]
882884001294	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
882884001295	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
882884001296	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
882884001297	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
882884001298	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
882884001299	dimerization domain swap beta strand [polypeptide binding]; other site
882884001300	regulatory protein interface [polypeptide binding]; other site
882884001301	active site
882884001302	regulatory phosphorylation site [posttranslational modification]; other site
882884001303	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
882884001304	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
882884001305	dimer interface [polypeptide binding]; other site
882884001306	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884001307	catalytic residue [active]
882884001308	putative sulfate transport protein CysZ; Validated; Region: PRK04949
882884001309	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
882884001310	cell division protein ZipA; Provisional; Region: PRK03427
882884001311	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
882884001312	FtsZ protein binding site [polypeptide binding]; other site
882884001313	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
882884001314	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
882884001315	nucleotide binding pocket [chemical binding]; other site
882884001316	K-X-D-G motif; other site
882884001317	catalytic site [active]
882884001318	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
882884001319	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
882884001320	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
882884001321	Dimer interface [polypeptide binding]; other site
882884001322	BRCT sequence motif; other site
882884001323	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
882884001324	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
882884001325	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
882884001326	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
882884001327	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
882884001328	active site
882884001329	HIGH motif; other site
882884001330	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
882884001331	active site
882884001332	KMSKS motif; other site
882884001333	Winged helix-turn helix; Region: HTH_29; pfam13551
882884001334	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
882884001335	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
882884001336	MASE1; Region: MASE1; pfam05231
882884001337	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
882884001338	diguanylate cyclase; Region: GGDEF; smart00267
882884001339	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
882884001340	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
882884001341	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
882884001342	Nucleoside recognition; Region: Gate; pfam07670
882884001343	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
882884001344	manganese transport protein MntH; Reviewed; Region: PRK00701
882884001345	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
882884001346	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
882884001347	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
882884001348	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
882884001349	active site
882884001350	catalytic tetrad [active]
882884001351	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
882884001352	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
882884001353	dimer interface [polypeptide binding]; other site
882884001354	PYR/PP interface [polypeptide binding]; other site
882884001355	TPP binding site [chemical binding]; other site
882884001356	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
882884001357	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
882884001358	TPP-binding site [chemical binding]; other site
882884001359	dimer interface [polypeptide binding]; other site
882884001360	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
882884001361	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
882884001362	Cl- selectivity filter; other site
882884001363	Cl- binding residues [ion binding]; other site
882884001364	pore gating glutamate residue; other site
882884001365	dimer interface [polypeptide binding]; other site
882884001366	glucokinase; Provisional; Region: glk; PRK00292
882884001367	glucokinase, proteobacterial type; Region: glk; TIGR00749
882884001368	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
882884001369	active site
882884001370	P-loop; other site
882884001371	phosphorylation site [posttranslational modification]
882884001372	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
882884001373	aminopeptidase; Provisional; Region: PRK09795
882884001374	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
882884001375	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
882884001376	active site
882884001377	exoaminopeptidase; Provisional; Region: PRK09961
882884001378	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
882884001379	oligomer interface [polypeptide binding]; other site
882884001380	active site
882884001381	metal binding site [ion binding]; metal-binding site
882884001382	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
882884001383	dimerization domain swap beta strand [polypeptide binding]; other site
882884001384	regulatory protein interface [polypeptide binding]; other site
882884001385	active site
882884001386	regulatory phosphorylation site [posttranslational modification]; other site
882884001387	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
882884001388	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
882884001389	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
882884001390	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
882884001391	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
882884001392	active site
882884001393	phosphorylation site [posttranslational modification]
882884001394	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
882884001395	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884001396	aminotransferase; Validated; Region: PRK08175
882884001397	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884001398	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884001399	homodimer interface [polypeptide binding]; other site
882884001400	catalytic residue [active]
882884001401	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
882884001402	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
882884001403	putative acyl-acceptor binding pocket; other site
882884001404	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
882884001405	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
882884001406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884001407	putative substrate translocation pore; other site
882884001408	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884001409	outer membrane protease; Reviewed; Region: PRK10993
882884001410	Integrase core domain; Region: rve_3; cl15866
882884001411	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884001412	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884001413	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
882884001414	sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022
882884001415	active site
882884001416	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
882884001417	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
882884001418	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
882884001419	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
882884001420	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
882884001421	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
882884001422	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
882884001423	dimer interface [polypeptide binding]; other site
882884001424	active site
882884001425	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
882884001426	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
882884001427	substrate binding site [chemical binding]; other site
882884001428	oxyanion hole (OAH) forming residues; other site
882884001429	trimer interface [polypeptide binding]; other site
882884001430	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
882884001431	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
882884001432	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
882884001433	catalytic core [active]
882884001434	hypothetical protein; Provisional; Region: PRK04946
882884001435	Smr domain; Region: Smr; pfam01713
882884001436	HemK family putative methylases; Region: hemK_fam; TIGR00536
882884001437	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884001438	S-adenosylmethionine binding site [chemical binding]; other site
882884001439	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
882884001440	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
882884001441	Tetramer interface [polypeptide binding]; other site
882884001442	active site
882884001443	FMN-binding site [chemical binding]; other site
882884001444	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
882884001445	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
882884001446	hypothetical protein; Provisional; Region: PRK10621
882884001447	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
882884001448	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
882884001449	YfcL protein; Region: YfcL; pfam08891
882884001450	Uncharacterized conserved protein [Function unknown]; Region: COG4121
882884001451	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
882884001452	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
882884001453	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
882884001454	dimer interface [polypeptide binding]; other site
882884001455	active site
882884001456	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
882884001457	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884001458	non-specific DNA binding site [nucleotide binding]; other site
882884001459	salt bridge; other site
882884001460	sequence-specific DNA binding site [nucleotide binding]; other site
882884001461	putative transporter; Provisional; Region: PRK12382
882884001462	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884001463	putative substrate translocation pore; other site
882884001464	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
882884001465	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
882884001466	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
882884001467	ligand binding site [chemical binding]; other site
882884001468	NAD binding site [chemical binding]; other site
882884001469	catalytic site [active]
882884001470	homodimer interface [polypeptide binding]; other site
882884001471	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
882884001472	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
882884001473	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
882884001474	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
882884001475	dimerization interface 3.5A [polypeptide binding]; other site
882884001476	active site
882884001477	hypothetical protein; Provisional; Region: PRK10847
882884001478	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
882884001479	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
882884001480	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
882884001481	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
882884001482	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
882884001483	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
882884001484	cell division protein DedD; Provisional; Region: PRK11633
882884001485	Sporulation related domain; Region: SPOR; pfam05036
882884001486	colicin V production protein; Provisional; Region: PRK10845
882884001487	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
882884001488	amidophosphoribosyltransferase; Provisional; Region: PRK09246
882884001489	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
882884001490	active site
882884001491	tetramer interface [polypeptide binding]; other site
882884001492	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
882884001493	active site
882884001494	PAS fold; Region: PAS_4; pfam08448
882884001495	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
882884001496	putative active site [active]
882884001497	heme pocket [chemical binding]; other site
882884001498	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
882884001499	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884001500	Walker A motif; other site
882884001501	ATP binding site [chemical binding]; other site
882884001502	Walker B motif; other site
882884001503	arginine finger; other site
882884001504	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
882884001505	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
882884001506	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
882884001507	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
882884001508	catalytic residue [active]
882884001509	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
882884001510	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
882884001511	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
882884001512	dimer interface [polypeptide binding]; other site
882884001513	active site
882884001514	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
882884001515	substrate binding site [chemical binding]; other site
882884001516	catalytic residue [active]
882884001517	gamma-aminobutyrate permease; Region: GABAperm; TIGR01773
882884001518	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
882884001519	Flavoprotein; Region: Flavoprotein; pfam02441
882884001520	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
882884001521	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884001522	substrate binding pocket [chemical binding]; other site
882884001523	membrane-bound complex binding site; other site
882884001524	hinge residues; other site
882884001525	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
882884001526	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884001527	substrate binding pocket [chemical binding]; other site
882884001528	membrane-bound complex binding site; other site
882884001529	hinge residues; other site
882884001530	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
882884001531	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884001532	dimer interface [polypeptide binding]; other site
882884001533	conserved gate region; other site
882884001534	putative PBP binding loops; other site
882884001535	ABC-ATPase subunit interface; other site
882884001536	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
882884001537	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884001538	dimer interface [polypeptide binding]; other site
882884001539	conserved gate region; other site
882884001540	putative PBP binding loops; other site
882884001541	ABC-ATPase subunit interface; other site
882884001542	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
882884001543	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
882884001544	Walker A/P-loop; other site
882884001545	ATP binding site [chemical binding]; other site
882884001546	Q-loop/lid; other site
882884001547	ABC transporter signature motif; other site
882884001548	Walker B; other site
882884001549	D-loop; other site
882884001550	H-loop/switch region; other site
882884001551	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
882884001552	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
882884001553	putative NAD(P) binding site [chemical binding]; other site
882884001554	putative active site [active]
882884001555	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
882884001556	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
882884001557	C-terminal domain interface [polypeptide binding]; other site
882884001558	GSH binding site (G-site) [chemical binding]; other site
882884001559	dimer interface [polypeptide binding]; other site
882884001560	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
882884001561	N-terminal domain interface [polypeptide binding]; other site
882884001562	putative dimer interface [polypeptide binding]; other site
882884001563	active site
882884001564	glutathione S-transferase; Provisional; Region: PRK15113
882884001565	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
882884001566	C-terminal domain interface [polypeptide binding]; other site
882884001567	GSH binding site (G-site) [chemical binding]; other site
882884001568	dimer interface [polypeptide binding]; other site
882884001569	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
882884001570	N-terminal domain interface [polypeptide binding]; other site
882884001571	putative dimer interface [polypeptide binding]; other site
882884001572	putative substrate binding pocket (H-site) [chemical binding]; other site
882884001573	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
882884001574	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
882884001575	active site
882884001576	metal binding site [ion binding]; metal-binding site
882884001577	homotetramer interface [polypeptide binding]; other site
882884001578	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
882884001579	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
882884001580	nudix motif; other site
882884001581	Transcriptional regulators [Transcription]; Region: PurR; COG1609
882884001582	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884001583	DNA binding site [nucleotide binding]
882884001584	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
882884001585	putative dimerization interface [polypeptide binding]; other site
882884001586	putative ligand binding site [chemical binding]; other site
882884001587	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
882884001588	active site
882884001589	phosphorylation site [posttranslational modification]
882884001590	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
882884001591	active site
882884001592	P-loop; other site
882884001593	phosphorylation site [posttranslational modification]
882884001594	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
882884001595	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
882884001596	TPP-binding site [chemical binding]; other site
882884001597	dimer interface [polypeptide binding]; other site
882884001598	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
882884001599	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
882884001600	PYR/PP interface [polypeptide binding]; other site
882884001601	dimer interface [polypeptide binding]; other site
882884001602	TPP binding site [chemical binding]; other site
882884001603	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
882884001604	hypothetical protein; Provisional; Region: PRK11588
882884001605	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
882884001606	phosphate acetyltransferase; Reviewed; Region: PRK05632
882884001607	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
882884001608	DRTGG domain; Region: DRTGG; pfam07085
882884001609	phosphate acetyltransferase; Region: pta; TIGR00651
882884001610	propionate/acetate kinase; Provisional; Region: PRK12379
882884001611	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
882884001612	hypothetical protein; Provisional; Region: PRK01816
882884001613	hypothetical protein; Validated; Region: PRK05445
882884001614	putative phosphatase; Provisional; Region: PRK11587
882884001615	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884001616	motif II; other site
882884001617	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
882884001618	transmembrane helices; other site
882884001619	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
882884001620	TrkA-C domain; Region: TrkA_C; pfam02080
882884001621	TrkA-C domain; Region: TrkA_C; pfam02080
882884001622	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
882884001623	5'-nucleotidase; Provisional; Region: PRK03826
882884001624	aminotransferase AlaT; Validated; Region: PRK09265
882884001625	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884001626	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884001627	homodimer interface [polypeptide binding]; other site
882884001628	catalytic residue [active]
882884001629	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
882884001630	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884001631	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
882884001632	putative dimerization interface [polypeptide binding]; other site
882884001633	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
882884001634	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
882884001635	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
882884001636	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
882884001637	NADH dehydrogenase subunit D; Validated; Region: PRK06075
882884001638	NADH dehydrogenase subunit E; Validated; Region: PRK07539
882884001639	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
882884001640	putative dimer interface [polypeptide binding]; other site
882884001641	[2Fe-2S] cluster binding site [ion binding]; other site
882884001642	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
882884001643	SLBB domain; Region: SLBB; pfam10531
882884001644	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
882884001645	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
882884001646	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
882884001647	catalytic loop [active]
882884001648	iron binding site [ion binding]; other site
882884001649	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
882884001650	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
882884001651	[4Fe-4S] binding site [ion binding]; other site
882884001652	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
882884001653	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
882884001654	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
882884001655	4Fe-4S binding domain; Region: Fer4; pfam00037
882884001656	4Fe-4S binding domain; Region: Fer4; pfam00037
882884001657	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
882884001658	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
882884001659	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
882884001660	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
882884001661	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
882884001662	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
882884001663	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
882884001664	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
882884001665	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
882884001666	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
882884001667	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
882884001668	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
882884001669	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884001670	active site
882884001671	phosphorylation site [posttranslational modification]
882884001672	intermolecular recognition site; other site
882884001673	dimerization interface [polypeptide binding]; other site
882884001674	ribonuclease BN; Region: true_RNase_BN; TIGR02649
882884001675	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884001676	Coenzyme A binding pocket [chemical binding]; other site
882884001677	hypothetical protein; Provisional; Region: PRK10404
882884001678	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
882884001679	isochorismate synthases; Region: isochor_syn; TIGR00543
882884001680	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
882884001681	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
882884001682	dimer interface [polypeptide binding]; other site
882884001683	tetramer interface [polypeptide binding]; other site
882884001684	PYR/PP interface [polypeptide binding]; other site
882884001685	TPP binding site [chemical binding]; other site
882884001686	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
882884001687	TPP-binding site; other site
882884001688	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
882884001689	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
882884001690	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
882884001691	substrate binding site [chemical binding]; other site
882884001692	oxyanion hole (OAH) forming residues; other site
882884001693	trimer interface [polypeptide binding]; other site
882884001694	O-succinylbenzoate synthase; Provisional; Region: PRK05105
882884001695	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
882884001696	active site
882884001697	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
882884001698	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
882884001699	acyl-activating enzyme (AAE) consensus motif; other site
882884001700	putative AMP binding site [chemical binding]; other site
882884001701	putative active site [active]
882884001702	putative CoA binding site [chemical binding]; other site
882884001703	signal transduction protein PmrD; Provisional; Region: PRK15450
882884001704	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
882884001705	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
882884001706	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
882884001707	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
882884001708	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
882884001709	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
882884001710	inhibitor-cofactor binding pocket; inhibition site
882884001711	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884001712	catalytic residue [active]
882884001713	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
882884001714	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
882884001715	catalytic core [active]
882884001716	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
882884001717	YfaZ precursor; Region: YfaZ; pfam07437
882884001718	hypothetical protein; Provisional; Region: PRK03673
882884001719	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
882884001720	putative MPT binding site; other site
882884001721	Competence-damaged protein; Region: CinA; cl00666
882884001722	deubiquitinase SseL; Provisional; Region: PRK14848
882884001723	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
882884001724	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
882884001725	Cysteine-rich domain; Region: CCG; pfam02754
882884001726	Cysteine-rich domain; Region: CCG; pfam02754
882884001727	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
882884001728	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
882884001729	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
882884001730	hydroxyglutarate oxidase; Provisional; Region: PRK11728
882884001731	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
882884001732	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
882884001733	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884001734	putative substrate translocation pore; other site
882884001735	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
882884001736	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
882884001737	active site
882884001738	catalytic site [active]
882884001739	metal binding site [ion binding]; metal-binding site
882884001740	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884001741	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884001742	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
882884001743	dimerization interface [polypeptide binding]; other site
882884001744	Major Facilitator Superfamily; Region: MFS_1; pfam07690
882884001745	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884001746	putative substrate translocation pore; other site
882884001747	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
882884001748	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
882884001749	catalytic loop [active]
882884001750	iron binding site [ion binding]; other site
882884001751	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
882884001752	dimer interface [polypeptide binding]; other site
882884001753	putative radical transfer pathway; other site
882884001754	diiron center [ion binding]; other site
882884001755	tyrosyl radical; other site
882884001756	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
882884001757	ATP cone domain; Region: ATP-cone; pfam03477
882884001758	Class I ribonucleotide reductase; Region: RNR_I; cd01679
882884001759	active site
882884001760	dimer interface [polypeptide binding]; other site
882884001761	catalytic residues [active]
882884001762	effector binding site; other site
882884001763	R2 peptide binding site; other site
882884001764	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
882884001765	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884001766	S-adenosylmethionine binding site [chemical binding]; other site
882884001767	DNA gyrase subunit A; Validated; Region: PRK05560
882884001768	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
882884001769	CAP-like domain; other site
882884001770	active site
882884001771	primary dimer interface [polypeptide binding]; other site
882884001772	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
882884001773	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
882884001774	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
882884001775	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
882884001776	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
882884001777	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
882884001778	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
882884001779	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884001780	dimer interface [polypeptide binding]; other site
882884001781	phosphorylation site [posttranslational modification]
882884001782	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884001783	ATP binding site [chemical binding]; other site
882884001784	Mg2+ binding site [ion binding]; other site
882884001785	G-X-G motif; other site
882884001786	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
882884001787	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884001788	active site
882884001789	phosphorylation site [posttranslational modification]
882884001790	intermolecular recognition site; other site
882884001791	dimerization interface [polypeptide binding]; other site
882884001792	transcriptional regulator RcsB; Provisional; Region: PRK10840
882884001793	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884001794	active site
882884001795	phosphorylation site [posttranslational modification]
882884001796	intermolecular recognition site; other site
882884001797	dimerization interface [polypeptide binding]; other site
882884001798	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884001799	DNA binding residues [nucleotide binding]
882884001800	dimerization interface [polypeptide binding]; other site
882884001801	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
882884001802	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
882884001803	trimer interface [polypeptide binding]; other site
882884001804	eyelet of channel; other site
882884001805	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
882884001806	ApbE family; Region: ApbE; pfam02424
882884001807	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
882884001808	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
882884001809	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884001810	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
882884001811	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
882884001812	DNA binding site [nucleotide binding]
882884001813	active site
882884001814	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
882884001815	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
882884001816	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
882884001817	Walker A/P-loop; other site
882884001818	ATP binding site [chemical binding]; other site
882884001819	Q-loop/lid; other site
882884001820	ABC transporter signature motif; other site
882884001821	Walker B; other site
882884001822	D-loop; other site
882884001823	H-loop/switch region; other site
882884001824	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
882884001825	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
882884001826	Sulfate transporter family; Region: Sulfate_transp; pfam00916
882884001827	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
882884001828	secondary substrate binding site; other site
882884001829	primary substrate binding site; other site
882884001830	inhibition loop; other site
882884001831	dimerization interface [polypeptide binding]; other site
882884001832	ferredoxin-type protein; Provisional; Region: PRK10194
882884001833	4Fe-4S binding domain; Region: Fer4; pfam00037
882884001834	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
882884001835	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
882884001836	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
882884001837	[4Fe-4S] binding site [ion binding]; other site
882884001838	molybdopterin cofactor binding site; other site
882884001839	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
882884001840	molybdopterin cofactor binding site; other site
882884001841	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
882884001842	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
882884001843	4Fe-4S binding domain; Region: Fer4_5; pfam12801
882884001844	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
882884001845	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
882884001846	cytochrome c-type protein NapC; Provisional; Region: PRK10617
882884001847	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
882884001848	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
882884001849	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
882884001850	Walker A/P-loop; other site
882884001851	ATP binding site [chemical binding]; other site
882884001852	Q-loop/lid; other site
882884001853	ABC transporter signature motif; other site
882884001854	Walker B; other site
882884001855	D-loop; other site
882884001856	H-loop/switch region; other site
882884001857	heme exporter protein CcmB; Region: ccmB; TIGR01190
882884001858	heme exporter protein CcmC; Region: ccmC; TIGR01191
882884001859	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
882884001860	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
882884001861	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
882884001862	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
882884001863	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
882884001864	catalytic residues [active]
882884001865	central insert; other site
882884001866	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
882884001867	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
882884001868	transcriptional regulator NarP; Provisional; Region: PRK10403
882884001869	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884001870	active site
882884001871	phosphorylation site [posttranslational modification]
882884001872	intermolecular recognition site; other site
882884001873	dimerization interface [polypeptide binding]; other site
882884001874	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884001875	DNA binding residues [nucleotide binding]
882884001876	dimerization interface [polypeptide binding]; other site
882884001877	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
882884001878	catalytic residue [active]
882884001879	ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydD; COG4988
882884001880	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
882884001881	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
882884001882	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
882884001883	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
882884001884	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
882884001885	Peptidase M35 family; Region: M35_like; cl03449
882884001886	active site
882884001887	Zn binding site [ion binding]; other site
882884001888	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
882884001889	Family description; Region: VCBS; pfam13517
882884001890	Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256
882884001891	Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255
882884001892	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
882884001893	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
882884001894	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884001895	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884001896	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
882884001897	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
882884001898	Sulfatase; Region: Sulfatase; cl17466
882884001899	hypothetical protein; Provisional; Region: PRK13689
882884001900	Nucleoid-associated protein [General function prediction only]; Region: COG3081
882884001901	nucleoid-associated protein NdpA; Validated; Region: PRK00378
882884001902	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
882884001903	5S rRNA interface [nucleotide binding]; other site
882884001904	CTC domain interface [polypeptide binding]; other site
882884001905	L16 interface [polypeptide binding]; other site
882884001906	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
882884001907	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884001908	ATP binding site [chemical binding]; other site
882884001909	putative Mg++ binding site [ion binding]; other site
882884001910	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884001911	nucleotide binding region [chemical binding]; other site
882884001912	ATP-binding site [chemical binding]; other site
882884001913	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
882884001914	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
882884001915	RNA binding surface [nucleotide binding]; other site
882884001916	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
882884001917	active site
882884001918	uracil binding [chemical binding]; other site
882884001919	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884001920	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
882884001921	putative substrate translocation pore; other site
882884001922	hypothetical protein; Provisional; Region: PRK11835
882884001923	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
882884001924	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884001925	Walker A/P-loop; other site
882884001926	ATP binding site [chemical binding]; other site
882884001927	Q-loop/lid; other site
882884001928	ABC transporter signature motif; other site
882884001929	Walker B; other site
882884001930	D-loop; other site
882884001931	H-loop/switch region; other site
882884001932	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
882884001933	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884001934	Walker A/P-loop; other site
882884001935	ATP binding site [chemical binding]; other site
882884001936	Q-loop/lid; other site
882884001937	ABC transporter signature motif; other site
882884001938	Walker B; other site
882884001939	D-loop; other site
882884001940	H-loop/switch region; other site
882884001941	microcin C ABC transporter permease; Provisional; Region: PRK15021
882884001942	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884001943	dimer interface [polypeptide binding]; other site
882884001944	conserved gate region; other site
882884001945	ABC-ATPase subunit interface; other site
882884001946	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
882884001947	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884001948	dimer interface [polypeptide binding]; other site
882884001949	conserved gate region; other site
882884001950	putative PBP binding loops; other site
882884001951	ABC-ATPase subunit interface; other site
882884001952	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
882884001953	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
882884001954	phage resistance protein; Provisional; Region: PRK10551
882884001955	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
882884001956	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
882884001957	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
882884001958	NlpC/P60 family; Region: NLPC_P60; pfam00877
882884001959	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
882884001960	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
882884001961	active site
882884001962	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
882884001963	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
882884001964	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
882884001965	elongation factor P; Provisional; Region: PRK04542
882884001966	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
882884001967	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
882884001968	RNA binding site [nucleotide binding]; other site
882884001969	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
882884001970	RNA binding site [nucleotide binding]; other site
882884001971	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
882884001972	sugar efflux transporter B; Provisional; Region: PRK15011
882884001973	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884001974	putative substrate translocation pore; other site
882884001975	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
882884001976	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
882884001977	active site
882884001978	phosphorylation site [posttranslational modification]
882884001979	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
882884001980	dimerization domain swap beta strand [polypeptide binding]; other site
882884001981	regulatory protein interface [polypeptide binding]; other site
882884001982	active site
882884001983	regulatory phosphorylation site [posttranslational modification]; other site
882884001984	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
882884001985	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
882884001986	putative substrate binding site [chemical binding]; other site
882884001987	putative ATP binding site [chemical binding]; other site
882884001988	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
882884001989	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
882884001990	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
882884001991	active site
882884001992	P-loop; other site
882884001993	phosphorylation site [posttranslational modification]
882884001994	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
882884001995	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
882884001996	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
882884001997	ligand binding site [chemical binding]; other site
882884001998	flexible hinge region; other site
882884001999	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
882884002000	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
882884002001	active site
882884002002	tetramer interface [polypeptide binding]; other site
882884002003	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
882884002004	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
882884002005	Nucleoside recognition; Region: Gate; pfam07670
882884002006	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
882884002007	endonuclease IV; Provisional; Region: PRK01060
882884002008	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
882884002009	AP (apurinic/apyrimidinic) site pocket; other site
882884002010	DNA interaction; other site
882884002011	Metal-binding active site; metal-binding site
882884002012	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
882884002013	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
882884002014	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884002015	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
882884002016	putative dimerization interface [polypeptide binding]; other site
882884002017	lysine transporter; Provisional; Region: PRK10836
882884002018	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
882884002019	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
882884002020	N-terminal plug; other site
882884002021	ligand-binding site [chemical binding]; other site
882884002022	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
882884002023	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884002024	putative substrate translocation pore; other site
882884002025	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
882884002026	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
882884002027	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884002028	motif II; other site
882884002029	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
882884002030	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
882884002031	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
882884002032	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884002033	sequence-specific DNA binding site [nucleotide binding]; other site
882884002034	salt bridge; other site
882884002035	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
882884002036	S-formylglutathione hydrolase; Region: PLN02442
882884002037	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
882884002038	GTP cyclohydrolase I; Provisional; Region: PLN03044
882884002039	active site
882884002040	Predicted membrane protein [Function unknown]; Region: COG2311
882884002041	hypothetical protein; Provisional; Region: PRK10835
882884002042	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
882884002043	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884002044	DNA binding site [nucleotide binding]
882884002045	domain linker motif; other site
882884002046	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
882884002047	dimerization interface (closed form) [polypeptide binding]; other site
882884002048	ligand binding site [chemical binding]; other site
882884002049	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
882884002050	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
882884002051	ligand binding site [chemical binding]; other site
882884002052	calcium binding site [ion binding]; other site
882884002053	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
882884002054	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
882884002055	Walker A/P-loop; other site
882884002056	ATP binding site [chemical binding]; other site
882884002057	Q-loop/lid; other site
882884002058	ABC transporter signature motif; other site
882884002059	Walker B; other site
882884002060	D-loop; other site
882884002061	H-loop/switch region; other site
882884002062	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
882884002063	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
882884002064	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
882884002065	TM-ABC transporter signature motif; other site
882884002066	4Fe-4S binding domain; Region: Fer4; cl02805
882884002067	insertion element IS2 transposase InsD; Provisional; Region: PRK14702
882884002068	Integrase core domain; Region: rve; pfam00665
882884002069	Integrase core domain; Region: rve_3; pfam13683
882884002070	Transposase; Region: HTH_Tnp_1; pfam01527
882884002071	Post-segregation antitoxin CcdA; Region: CcdA; cl02188
882884002072	CcdB protein; Region: CcdB; cl03380
882884002073	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
882884002074	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
882884002075	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
882884002076	putative active site [active]
882884002077	Homeodomain-like domain; Region: HTH_23; pfam13384
882884002078	Winged helix-turn helix; Region: HTH_29; pfam13551
882884002079	Homeodomain-like domain; Region: HTH_32; pfam13565
882884002080	cytidine deaminase; Provisional; Region: PRK09027
882884002081	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
882884002082	active site
882884002083	catalytic motif [active]
882884002084	Zn binding site [ion binding]; other site
882884002085	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
882884002086	active site
882884002087	catalytic motif [active]
882884002088	Zn binding site [ion binding]; other site
882884002089	hypothetical protein; Provisional; Region: PRK10711
882884002090	hypothetical protein; Provisional; Region: PRK01821
882884002091	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
882884002092	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884002093	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884002094	dimerization interface [polypeptide binding]; other site
882884002095	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884002096	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884002097	putative substrate translocation pore; other site
882884002098	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
882884002099	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
882884002100	FMN binding site [chemical binding]; other site
882884002101	active site
882884002102	catalytic residues [active]
882884002103	substrate binding site [chemical binding]; other site
882884002104	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
882884002105	oxidoreductase; Provisional; Region: PRK12743
882884002106	classical (c) SDRs; Region: SDR_c; cd05233
882884002107	NAD(P) binding site [chemical binding]; other site
882884002108	active site
882884002109	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
882884002110	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
882884002111	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
882884002112	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
882884002113	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
882884002114	D-lactate dehydrogenase; Provisional; Region: PRK11183
882884002115	FAD binding domain; Region: FAD_binding_4; pfam01565
882884002116	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
882884002117	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
882884002118	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
882884002119	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
882884002120	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
882884002121	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884002122	dimer interface [polypeptide binding]; other site
882884002123	conserved gate region; other site
882884002124	ABC-ATPase subunit interface; other site
882884002125	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
882884002126	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
882884002127	Walker A/P-loop; other site
882884002128	ATP binding site [chemical binding]; other site
882884002129	Q-loop/lid; other site
882884002130	ABC transporter signature motif; other site
882884002131	Walker B; other site
882884002132	D-loop; other site
882884002133	H-loop/switch region; other site
882884002134	CBS domain; Region: CBS; pfam00571
882884002135	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884002136	putative PBP binding loops; other site
882884002137	ABC-ATPase subunit interface; other site
882884002138	transcriptional regulator MirA; Provisional; Region: PRK15043
882884002139	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
882884002140	DNA binding residues [nucleotide binding]
882884002141	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
882884002142	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
882884002143	GAF domain; Region: GAF; pfam01590
882884002144	Histidine kinase; Region: His_kinase; pfam06580
882884002145	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884002146	ATP binding site [chemical binding]; other site
882884002147	Mg2+ binding site [ion binding]; other site
882884002148	G-X-G motif; other site
882884002149	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
882884002150	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884002151	active site
882884002152	phosphorylation site [posttranslational modification]
882884002153	intermolecular recognition site; other site
882884002154	dimerization interface [polypeptide binding]; other site
882884002155	LytTr DNA-binding domain; Region: LytTR; pfam04397
882884002156	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
882884002157	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
882884002158	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
882884002159	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
882884002160	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
882884002161	active site
882884002162	HIGH motif; other site
882884002163	KMSKS motif; other site
882884002164	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
882884002165	tRNA binding surface [nucleotide binding]; other site
882884002166	anticodon binding site; other site
882884002167	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
882884002168	dimer interface [polypeptide binding]; other site
882884002169	putative tRNA-binding site [nucleotide binding]; other site
882884002170	antiporter inner membrane protein; Provisional; Region: PRK11670
882884002171	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
882884002172	Walker A motif; other site
882884002173	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
882884002174	fimbrial chaperone protein; Provisional; Region: PRK15220
882884002175	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
882884002176	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
882884002177	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
882884002178	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
882884002179	PapC N-terminal domain; Region: PapC_N; pfam13954
882884002180	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
882884002181	PapC C-terminal domain; Region: PapC_C; pfam13953
882884002182	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
882884002183	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
882884002184	Predicted integral membrane protein [Function unknown]; Region: COG5455
882884002185	TPP riboswitch (THI element)
882884002186	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
882884002187	substrate binding site [chemical binding]; other site
882884002188	multimerization interface [polypeptide binding]; other site
882884002189	ATP binding site [chemical binding]; other site
882884002190	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
882884002191	dimer interface [polypeptide binding]; other site
882884002192	substrate binding site [chemical binding]; other site
882884002193	ATP binding site [chemical binding]; other site
882884002194	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
882884002195	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884002196	DNA-binding site [nucleotide binding]; DNA binding site
882884002197	UTRA domain; Region: UTRA; pfam07702
882884002198	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
882884002199	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
882884002200	putative active site; other site
882884002201	catalytic residue [active]
882884002202	lipid kinase; Reviewed; Region: PRK13054
882884002203	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
882884002204	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
882884002205	putative protease; Provisional; Region: PRK15452
882884002206	Peptidase family U32; Region: Peptidase_U32; pfam01136
882884002207	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
882884002208	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884002209	active site
882884002210	phosphorylation site [posttranslational modification]
882884002211	intermolecular recognition site; other site
882884002212	dimerization interface [polypeptide binding]; other site
882884002213	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884002214	DNA binding site [nucleotide binding]
882884002215	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
882884002216	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884002217	dimerization interface [polypeptide binding]; other site
882884002218	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884002219	dimer interface [polypeptide binding]; other site
882884002220	phosphorylation site [posttranslational modification]
882884002221	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884002222	ATP binding site [chemical binding]; other site
882884002223	Mg2+ binding site [ion binding]; other site
882884002224	G-X-G motif; other site
882884002225	putative transporter; Provisional; Region: PRK10504
882884002226	putative transporter; Provisional; Region: PRK10504
882884002227	putative transporter; Provisional; Region: PRK10504
882884002228	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
882884002229	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
882884002230	Protein export membrane protein; Region: SecD_SecF; cl14618
882884002231	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
882884002232	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
882884002233	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884002234	putative chaperone; Provisional; Region: PRK11678
882884002235	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
882884002236	putative NEF/HSP70 interaction site [polypeptide binding]; other site
882884002237	nucleotide binding site [chemical binding]; other site
882884002238	SBD interface [polypeptide binding]; other site
882884002239	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
882884002240	AlkA N-terminal domain; Region: AlkA_N; pfam06029
882884002241	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
882884002242	minor groove reading motif; other site
882884002243	helix-hairpin-helix signature motif; other site
882884002244	substrate binding pocket [chemical binding]; other site
882884002245	active site
882884002246	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
882884002247	PAS domain S-box; Region: sensory_box; TIGR00229
882884002248	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
882884002249	putative active site [active]
882884002250	heme pocket [chemical binding]; other site
882884002251	PAS domain S-box; Region: sensory_box; TIGR00229
882884002252	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
882884002253	putative active site [active]
882884002254	heme pocket [chemical binding]; other site
882884002255	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
882884002256	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
882884002257	metal binding site [ion binding]; metal-binding site
882884002258	active site
882884002259	I-site; other site
882884002260	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
882884002261	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
882884002262	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
882884002263	ATP-binding site [chemical binding]; other site
882884002264	Sugar specificity; other site
882884002265	Pyrimidine base specificity; other site
882884002266	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
882884002267	trimer interface [polypeptide binding]; other site
882884002268	active site
882884002269	putative assembly protein; Provisional; Region: PRK10833
882884002270	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
882884002271	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
882884002272	FOG: CBS domain [General function prediction only]; Region: COG0517
882884002273	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
882884002274	Transporter associated domain; Region: CorC_HlyC; smart01091
882884002275	polysaccharide export protein Wza; Provisional; Region: PRK15078
882884002276	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
882884002277	Low molecular weight phosphatase family; Region: LMWPc; cd00115
882884002278	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
882884002279	active site
882884002280	tyrosine kinase; Provisional; Region: PRK11519
882884002281	Chain length determinant protein; Region: Wzz; pfam02706
882884002282	Chain length determinant protein; Region: Wzz; cl15801
882884002283	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
882884002284	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
882884002285	putative glycosyl transferase; Provisional; Region: PRK10018
882884002286	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
882884002287	active site
882884002288	putative acyl transferase; Provisional; Region: PRK10191
882884002289	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
882884002290	trimer interface [polypeptide binding]; other site
882884002291	active site
882884002292	substrate binding site [chemical binding]; other site
882884002293	CoA binding site [chemical binding]; other site
882884002294	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
882884002295	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
882884002296	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
882884002297	putative colanic acid biosynthesis protein; Provisional; Region: wcaD; cl08075
882884002298	putative glycosyl transferase; Provisional; Region: PRK10063
882884002299	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
882884002300	metal-binding site
882884002301	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
882884002302	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
882884002303	putative trimer interface [polypeptide binding]; other site
882884002304	putative active site [active]
882884002305	putative substrate binding site [chemical binding]; other site
882884002306	putative CoA binding site [chemical binding]; other site
882884002307	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
882884002308	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
882884002309	NADP-binding site; other site
882884002310	homotetramer interface [polypeptide binding]; other site
882884002311	substrate binding site [chemical binding]; other site
882884002312	homodimer interface [polypeptide binding]; other site
882884002313	active site
882884002314	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
882884002315	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
882884002316	NADP binding site [chemical binding]; other site
882884002317	active site
882884002318	putative substrate binding site [chemical binding]; other site
882884002319	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
882884002320	active site
882884002321	GDP-Mannose binding site [chemical binding]; other site
882884002322	dimer interface [polypeptide binding]; other site
882884002323	modified nudix motif
882884002324	metal binding site [ion binding]; metal-binding site
882884002325	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
882884002326	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
882884002327	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
882884002328	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
882884002329	Substrate binding site; other site
882884002330	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
882884002331	phosphomannomutase CpsG; Provisional; Region: PRK15414
882884002332	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
882884002333	active site
882884002334	substrate binding site [chemical binding]; other site
882884002335	metal binding site [ion binding]; metal-binding site
882884002336	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
882884002337	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
882884002338	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
882884002339	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
882884002340	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
882884002341	NAD(P) binding site [chemical binding]; other site
882884002342	homodimer interface [polypeptide binding]; other site
882884002343	substrate binding site [chemical binding]; other site
882884002344	active site
882884002345	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
882884002346	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
882884002347	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
882884002348	NADP binding site [chemical binding]; other site
882884002349	active site
882884002350	putative substrate binding site [chemical binding]; other site
882884002351	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
882884002352	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
882884002353	active site
882884002354	homodimer interface [polypeptide binding]; other site
882884002355	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
882884002356	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
882884002357	cupin fold metalloprotein, WbuC family; Region: cupin_WbuC; TIGR04366
882884002358	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
882884002359	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
882884002360	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
882884002361	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
882884002362	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
882884002363	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
882884002364	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
882884002365	chain length determinant protein WzzB; Provisional; Region: PRK15471
882884002366	Chain length determinant protein; Region: Wzz; cl15801
882884002367	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
882884002368	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
882884002369	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
882884002370	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
882884002371	metal binding site [ion binding]; metal-binding site
882884002372	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
882884002373	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
882884002374	substrate binding site [chemical binding]; other site
882884002375	glutamase interaction surface [polypeptide binding]; other site
882884002376	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
882884002377	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
882884002378	catalytic residues [active]
882884002379	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
882884002380	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
882884002381	putative active site [active]
882884002382	oxyanion strand; other site
882884002383	catalytic triad [active]
882884002384	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
882884002385	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884002386	active site
882884002387	motif I; other site
882884002388	motif II; other site
882884002389	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
882884002390	putative active site pocket [active]
882884002391	4-fold oligomerization interface [polypeptide binding]; other site
882884002392	metal binding residues [ion binding]; metal-binding site
882884002393	3-fold/trimer interface [polypeptide binding]; other site
882884002394	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
882884002395	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884002396	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884002397	homodimer interface [polypeptide binding]; other site
882884002398	catalytic residue [active]
882884002399	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
882884002400	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
882884002401	NAD binding site [chemical binding]; other site
882884002402	dimerization interface [polypeptide binding]; other site
882884002403	product binding site; other site
882884002404	substrate binding site [chemical binding]; other site
882884002405	zinc binding site [ion binding]; other site
882884002406	catalytic residues [active]
882884002407	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
882884002408	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
882884002409	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
882884002410	histidine operon leader
882884002411	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
882884002412	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
882884002413	putative NAD(P) binding site [chemical binding]; other site
882884002414	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
882884002415	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
882884002416	exonuclease I; Provisional; Region: sbcB; PRK11779
882884002417	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
882884002418	active site
882884002419	catalytic site [active]
882884002420	substrate binding site [chemical binding]; other site
882884002421	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
882884002422	thiosulfate reductase PhsA; Provisional; Region: PRK15488
882884002423	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
882884002424	putative [Fe4-S4] binding site [ion binding]; other site
882884002425	putative molybdopterin cofactor binding site [chemical binding]; other site
882884002426	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
882884002427	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
882884002428	putative molybdopterin cofactor binding site; other site
882884002429	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
882884002430	4Fe-4S binding domain; Region: Fer4; cl02805
882884002431	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
882884002432	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
882884002433	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
882884002434	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
882884002435	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
882884002436	DNA gyrase inhibitor; Provisional; Region: PRK10016
882884002437	Predicted membrane protein [Function unknown]; Region: COG1289
882884002438	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
882884002439	hypothetical protein; Provisional; Region: PRK05423
882884002440	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
882884002441	propionate kinase; Reviewed; Region: PRK12397
882884002442	propionate/acetate kinase; Provisional; Region: PRK12379
882884002443	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
882884002444	G1 box; other site
882884002445	GTP/Mg2+ binding site [chemical binding]; other site
882884002446	G2 box; other site
882884002447	G3 box; other site
882884002448	Switch II region; other site
882884002449	G4 box; other site
882884002450	G5 box; other site
882884002451	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
882884002452	putative hexamer interface [polypeptide binding]; other site
882884002453	putative hexagonal pore; other site
882884002454	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
882884002455	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
882884002456	putative hexamer interface [polypeptide binding]; other site
882884002457	putative hexagonal pore; other site
882884002458	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
882884002459	putative hexamer interface [polypeptide binding]; other site
882884002460	putative hexagonal pore; other site
882884002461	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
882884002462	SLBB domain; Region: SLBB; pfam10531
882884002463	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
882884002464	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
882884002465	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
882884002466	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
882884002467	putative active site [active]
882884002468	metal binding site [ion binding]; metal-binding site
882884002469	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
882884002470	putative catalytic cysteine [active]
882884002471	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
882884002472	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
882884002473	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cl01889
882884002474	Hexamer/Pentamer interface [polypeptide binding]; other site
882884002475	central pore; other site
882884002476	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
882884002477	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
882884002478	Propanediol utilisation protein PduL; Region: PduL; pfam06130
882884002479	Propanediol utilisation protein PduL; Region: PduL; pfam06130
882884002480	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
882884002481	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
882884002482	putative hexamer interface [polypeptide binding]; other site
882884002483	putative hexagonal pore; other site
882884002484	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
882884002485	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
882884002486	Hexamer interface [polypeptide binding]; other site
882884002487	Putative hexagonal pore residue; other site
882884002488	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
882884002489	Cell division protein FtsA; Region: FtsA; cl17206
882884002490	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
882884002491	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
882884002492	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
882884002493	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
882884002494	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
882884002495	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
882884002496	alpha-beta subunit interface [polypeptide binding]; other site
882884002497	alpha-gamma subunit interface [polypeptide binding]; other site
882884002498	active site
882884002499	substrate and K+ binding site; other site
882884002500	K+ binding site [ion binding]; other site
882884002501	cobalamin binding site [chemical binding]; other site
882884002502	propanediol utilization protein PduB; Provisional; Region: PRK15415
882884002503	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
882884002504	putative hexamer interface [polypeptide binding]; other site
882884002505	putative hexagonal pore; other site
882884002506	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
882884002507	putative hexamer interface [polypeptide binding]; other site
882884002508	putative hexagonal pore; other site
882884002509	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
882884002510	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
882884002511	Hexamer interface [polypeptide binding]; other site
882884002512	Putative hexagonal pore residue; other site
882884002513	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
882884002514	amphipathic channel; other site
882884002515	Asn-Pro-Ala signature motifs; other site
882884002516	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
882884002517	Sensory domain found in PocR; Region: PocR; pfam10114
882884002518	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884002519	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
882884002520	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884002521	cobalamin riboswitch
882884002522	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
882884002523	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
882884002524	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
882884002525	catalytic triad [active]
882884002526	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
882884002527	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
882884002528	Precorrin-8X methylmutase; Region: CbiC; pfam02570
882884002529	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
882884002530	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
882884002531	active site
882884002532	putative homodimer interface [polypeptide binding]; other site
882884002533	SAM binding site [chemical binding]; other site
882884002534	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
882884002535	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884002536	S-adenosylmethionine binding site [chemical binding]; other site
882884002537	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
882884002538	active site
882884002539	SAM binding site [chemical binding]; other site
882884002540	homodimer interface [polypeptide binding]; other site
882884002541	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
882884002542	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
882884002543	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
882884002544	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
882884002545	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
882884002546	active site
882884002547	SAM binding site [chemical binding]; other site
882884002548	homodimer interface [polypeptide binding]; other site
882884002549	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
882884002550	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
882884002551	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
882884002552	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
882884002553	active site
882884002554	C-terminal domain interface [polypeptide binding]; other site
882884002555	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
882884002556	active site
882884002557	N-terminal domain interface [polypeptide binding]; other site
882884002558	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
882884002559	active site
882884002560	SAM binding site [chemical binding]; other site
882884002561	homodimer interface [polypeptide binding]; other site
882884002562	cobalt transport protein CbiM; Validated; Region: PRK08319
882884002563	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
882884002564	cobalt transport protein CbiN; Provisional; Region: PRK02898
882884002565	cobalt transport protein CbiQ; Provisional; Region: PRK15485
882884002566	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
882884002567	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
882884002568	Walker A/P-loop; other site
882884002569	ATP binding site [chemical binding]; other site
882884002570	Q-loop/lid; other site
882884002571	ABC transporter signature motif; other site
882884002572	Walker B; other site
882884002573	D-loop; other site
882884002574	H-loop/switch region; other site
882884002575	cobyric acid synthase; Provisional; Region: PRK00784
882884002576	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
882884002577	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
882884002578	catalytic triad [active]
882884002579	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
882884002580	homotrimer interface [polypeptide binding]; other site
882884002581	Walker A motif; other site
882884002582	GTP binding site [chemical binding]; other site
882884002583	Walker B motif; other site
882884002584	cobalamin synthase; Reviewed; Region: cobS; PRK00235
882884002585	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
882884002586	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
882884002587	putative dimer interface [polypeptide binding]; other site
882884002588	active site pocket [active]
882884002589	putative cataytic base [active]
882884002590	L,D-transpeptidase; Provisional; Region: PRK10190
882884002591	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
882884002592	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
882884002593	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
882884002594	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
882884002595	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884002596	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
882884002597	MATE family multidrug exporter; Provisional; Region: PRK10189
882884002598	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
882884002599	AMP nucleosidase; Provisional; Region: PRK08292
882884002600	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
882884002601	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
882884002602	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884002603	Peptidase family C69; Region: Peptidase_C69; cl17793
882884002604	Integrase core domain; Region: rve_3; pfam13683
882884002605	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
882884002606	Integrase core domain; Region: rve; pfam00665
882884002607	Transposase; Region: HTH_Tnp_1; pfam01527
882884002608	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
882884002609	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
882884002610	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
882884002611	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884002612	dimer interface [polypeptide binding]; other site
882884002613	conserved gate region; other site
882884002614	putative PBP binding loops; other site
882884002615	ABC-ATPase subunit interface; other site
882884002616	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884002617	dimer interface [polypeptide binding]; other site
882884002618	conserved gate region; other site
882884002619	putative PBP binding loops; other site
882884002620	ABC-ATPase subunit interface; other site
882884002621	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
882884002622	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884002623	Walker A/P-loop; other site
882884002624	ATP binding site [chemical binding]; other site
882884002625	Q-loop/lid; other site
882884002626	ABC transporter signature motif; other site
882884002627	Walker B; other site
882884002628	D-loop; other site
882884002629	H-loop/switch region; other site
882884002630	TOBE domain; Region: TOBE_2; pfam08402
882884002631	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
882884002632	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
882884002633	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
882884002634	type III secretion protein GogB; Provisional; Region: PRK15386
882884002635	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
882884002636	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
882884002637	amidase catalytic site [active]
882884002638	Zn binding residues [ion binding]; other site
882884002639	substrate binding site [chemical binding]; other site
882884002640	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
882884002641	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884002642	DNA binding site [nucleotide binding]
882884002643	active site
882884002644	Int/Topo IB signature motif; other site
882884002645	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
882884002646	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884002647	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884002648	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
882884002649	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
882884002650	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
882884002651	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
882884002652	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
882884002653	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
882884002654	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
882884002655	Transposase; Region: HTH_Tnp_1; cl17663
882884002656	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
882884002657	Helix-turn-helix domain; Region: HTH_36; pfam13730
882884002658	DNA-binding protein H-NS [General function prediction only]; Region: Hns; COG2916
882884002659	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
882884002660	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
882884002661	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
882884002662	Transposase; Region: HTH_Tnp_1; cl17663
882884002663	putative transposase OrfB; Reviewed; Region: PHA02517
882884002664	HTH-like domain; Region: HTH_21; pfam13276
882884002665	Integrase core domain; Region: rve; pfam00665
882884002666	Integrase core domain; Region: rve_2; pfam13333
882884002667	secreted effector protein PipB; Provisional; Region: PRK15197
882884002668	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
882884002669	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
882884002670	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
882884002671	DNA-binding site [nucleotide binding]; DNA binding site
882884002672	RNA-binding motif; other site
882884002673	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884002674	Helix-turn-helix domain; Region: HTH_28; pfam13518
882884002675	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
882884002676	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
882884002677	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
882884002678	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
882884002679	DNA cytosine methylase; Provisional; Region: PRK10458
882884002680	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
882884002681	cofactor binding site; other site
882884002682	DNA binding site [nucleotide binding]
882884002683	substrate interaction site [chemical binding]; other site
882884002684	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
882884002685	additional DNA contacts [nucleotide binding]; other site
882884002686	mismatch recognition site; other site
882884002687	active site
882884002688	zinc binding site [ion binding]; other site
882884002689	DNA intercalation site [nucleotide binding]; other site
882884002690	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
882884002691	EamA-like transporter family; Region: EamA; pfam00892
882884002692	EamA-like transporter family; Region: EamA; pfam00892
882884002693	hypothetical protein; Provisional; Region: PRK10062
882884002694	Uncharacterized small protein [Function unknown]; Region: COG5475
882884002695	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
882884002696	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
882884002697	metal binding site [ion binding]; metal-binding site
882884002698	active site
882884002699	I-site; other site
882884002700	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
882884002701	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884002702	active site
882884002703	motif I; other site
882884002704	motif II; other site
882884002705	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
882884002706	hypothetical protein; Provisional; Region: PRK10708
882884002707	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
882884002708	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884002709	DNA binding residues [nucleotide binding]
882884002710	dimerization interface [polypeptide binding]; other site
882884002711	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
882884002712	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
882884002713	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
882884002714	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
882884002715	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
882884002716	flagellar motor switch protein; Validated; Region: fliN; PRK05698
882884002717	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
882884002718	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
882884002719	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
882884002720	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
882884002721	flagellar hook-length control protein; Provisional; Region: PRK10118
882884002722	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
882884002723	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
882884002724	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
882884002725	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
882884002726	Walker A motif/ATP binding site; other site
882884002727	Walker B motif; other site
882884002728	flagellar assembly protein H; Validated; Region: fliH; PRK05687
882884002729	Flagellar assembly protein FliH; Region: FliH; pfam02108
882884002730	flagellar motor switch protein FliG; Region: fliG; TIGR00207
882884002731	FliG C-terminal domain; Region: FliG_C; pfam01706
882884002732	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
882884002733	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
882884002734	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
882884002735	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
882884002736	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
882884002737	CPxP  motif; other site
882884002738	putative inner membrane protein; Provisional; Region: PRK11099
882884002739	lipoprotein; Provisional; Region: PRK10397
882884002740	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
882884002741	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
882884002742	flagellar protein FliS; Validated; Region: fliS; PRK05685
882884002743	flagellar capping protein; Reviewed; Region: fliD; PRK08032
882884002744	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
882884002745	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
882884002746	flagellin; Validated; Region: PRK06819
882884002747	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
882884002748	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
882884002749	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
882884002750	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
882884002751	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
882884002752	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
882884002753	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
882884002754	DNA binding residues [nucleotide binding]
882884002755	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
882884002756	cystine transporter subunit; Provisional; Region: PRK11260
882884002757	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884002758	substrate binding pocket [chemical binding]; other site
882884002759	membrane-bound complex binding site; other site
882884002760	hinge residues; other site
882884002761	D-cysteine desulfhydrase; Validated; Region: PRK03910
882884002762	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
882884002763	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884002764	catalytic residue [active]
882884002765	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
882884002766	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884002767	dimer interface [polypeptide binding]; other site
882884002768	conserved gate region; other site
882884002769	putative PBP binding loops; other site
882884002770	ABC-ATPase subunit interface; other site
882884002771	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
882884002772	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
882884002773	Walker A/P-loop; other site
882884002774	ATP binding site [chemical binding]; other site
882884002775	Q-loop/lid; other site
882884002776	ABC transporter signature motif; other site
882884002777	Walker B; other site
882884002778	D-loop; other site
882884002779	H-loop/switch region; other site
882884002780	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
882884002781	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
882884002782	Autoinducer binding domain; Region: Autoind_bind; pfam03472
882884002783	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884002784	DNA binding residues [nucleotide binding]
882884002785	dimerization interface [polypeptide binding]; other site
882884002786	hypothetical protein; Provisional; Region: PRK10613
882884002787	response regulator; Provisional; Region: PRK09483
882884002788	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884002789	active site
882884002790	phosphorylation site [posttranslational modification]
882884002791	intermolecular recognition site; other site
882884002792	dimerization interface [polypeptide binding]; other site
882884002793	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884002794	DNA binding residues [nucleotide binding]
882884002795	dimerization interface [polypeptide binding]; other site
882884002796	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
882884002797	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
882884002798	GIY-YIG motif/motif A; other site
882884002799	active site
882884002800	catalytic site [active]
882884002801	putative DNA binding site [nucleotide binding]; other site
882884002802	metal binding site [ion binding]; metal-binding site
882884002803	UvrB/uvrC motif; Region: UVR; pfam02151
882884002804	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
882884002805	Helix-hairpin-helix motif; Region: HHH; pfam00633
882884002806	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
882884002807	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
882884002808	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
882884002809	NlpC/P60 family; Region: NLPC_P60; cl17555
882884002810	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
882884002811	hypothetical protein; Provisional; Region: PRK10396
882884002812	yecA family protein; Region: ygfB_yecA; TIGR02292
882884002813	SEC-C motif; Region: SEC-C; pfam02810
882884002814	tyrosine transporter TyrP; Provisional; Region: PRK15132
882884002815	aromatic amino acid transport protein; Region: araaP; TIGR00837
882884002816	probable metal-binding protein; Region: matur_matur; TIGR03853
882884002817	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
882884002818	Ferritin-like domain; Region: Ferritin; pfam00210
882884002819	ferroxidase diiron center [ion binding]; other site
882884002820	YecR-like lipoprotein; Region: YecR; pfam13992
882884002821	hypothetical protein; Provisional; Region: PRK09273
882884002822	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
882884002823	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
882884002824	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
882884002825	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
882884002826	Ferritin-like domain; Region: Ferritin; pfam00210
882884002827	ferroxidase diiron center [ion binding]; other site
882884002828	DJ-1 family protein; Region: not_thiJ; TIGR01383
882884002829	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
882884002830	conserved cys residue [active]
882884002831	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
882884002832	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
882884002833	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
882884002834	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
882884002835	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
882884002836	active site
882884002837	homotetramer interface [polypeptide binding]; other site
882884002838	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
882884002839	Ligand Binding Site [chemical binding]; other site
882884002840	transcriptional activator FlhD; Provisional; Region: PRK02909
882884002841	transcriptional activator FlhC; Provisional; Region: PRK12722
882884002842	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
882884002843	flagellar motor protein MotA; Validated; Region: PRK09110
882884002844	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
882884002845	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
882884002846	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
882884002847	ligand binding site [chemical binding]; other site
882884002848	chemotaxis protein CheA; Provisional; Region: PRK10547
882884002849	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
882884002850	putative binding surface; other site
882884002851	active site
882884002852	CheY binding; Region: CheY-binding; pfam09078
882884002853	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
882884002854	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884002855	ATP binding site [chemical binding]; other site
882884002856	Mg2+ binding site [ion binding]; other site
882884002857	G-X-G motif; other site
882884002858	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
882884002859	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
882884002860	putative CheA interaction surface; other site
882884002861	Spore Coat Protein U domain; Region: SCPU; pfam05229
882884002862	Spore Coat Protein U domain; Region: SCPU; pfam05229
882884002863	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
882884002864	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
882884002865	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
882884002866	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
882884002867	PapC N-terminal domain; Region: PapC_N; pfam13954
882884002868	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
882884002869	PapC C-terminal domain; Region: PapC_C; pfam13953
882884002870	Spore Coat Protein U domain; Region: SCPU; pfam05229
882884002871	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
882884002872	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
882884002873	dimer interface [polypeptide binding]; other site
882884002874	ligand binding site [chemical binding]; other site
882884002875	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884002876	dimerization interface [polypeptide binding]; other site
882884002877	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
882884002878	dimer interface [polypeptide binding]; other site
882884002879	putative CheW interface [polypeptide binding]; other site
882884002880	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
882884002881	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
882884002882	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884002883	S-adenosylmethionine binding site [chemical binding]; other site
882884002884	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
882884002885	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884002886	active site
882884002887	phosphorylation site [posttranslational modification]
882884002888	intermolecular recognition site; other site
882884002889	dimerization interface [polypeptide binding]; other site
882884002890	CheB methylesterase; Region: CheB_methylest; pfam01339
882884002891	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
882884002892	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884002893	active site
882884002894	phosphorylation site [posttranslational modification]
882884002895	intermolecular recognition site; other site
882884002896	dimerization interface [polypeptide binding]; other site
882884002897	chemotaxis regulator CheZ; Provisional; Region: PRK11166
882884002898	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
882884002899	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
882884002900	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
882884002901	FHIPEP family; Region: FHIPEP; pfam00771
882884002902	Flagellar protein FlhE; Region: FlhE; pfam06366
882884002903	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
882884002904	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
882884002905	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
882884002906	penicillin-binding protein 2; Provisional; Region: PRK10795
882884002907	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
882884002908	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
882884002909	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
882884002910	arginyl-tRNA synthetase; Region: argS; TIGR00456
882884002911	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
882884002912	active site
882884002913	HIGH motif; other site
882884002914	KMSK motif region; other site
882884002915	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
882884002916	tRNA binding surface [nucleotide binding]; other site
882884002917	anticodon binding site; other site
882884002918	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
882884002919	putative metal binding site [ion binding]; other site
882884002920	copper homeostasis protein CutC; Provisional; Region: PRK11572
882884002921	Methyltransferase domain; Region: Methyltransf_23; pfam13489
882884002922	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884002923	S-adenosylmethionine binding site [chemical binding]; other site
882884002924	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884002925	S-adenosylmethionine binding site [chemical binding]; other site
882884002926	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
882884002927	hypothetical protein; Provisional; Region: PRK10302
882884002928	Isochorismatase family; Region: Isochorismatase; pfam00857
882884002929	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
882884002930	catalytic triad [active]
882884002931	conserved cis-peptide bond; other site
882884002932	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
882884002933	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
882884002934	dimer interface [polypeptide binding]; other site
882884002935	anticodon binding site; other site
882884002936	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
882884002937	homodimer interface [polypeptide binding]; other site
882884002938	motif 1; other site
882884002939	active site
882884002940	motif 2; other site
882884002941	GAD domain; Region: GAD; pfam02938
882884002942	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
882884002943	active site
882884002944	motif 3; other site
882884002945	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
882884002946	nudix motif; other site
882884002947	hypothetical protein; Validated; Region: PRK00110
882884002948	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
882884002949	active site
882884002950	putative DNA-binding cleft [nucleotide binding]; other site
882884002951	dimer interface [polypeptide binding]; other site
882884002952	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
882884002953	RuvA N terminal domain; Region: RuvA_N; pfam01330
882884002954	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
882884002955	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
882884002956	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884002957	Walker A motif; other site
882884002958	ATP binding site [chemical binding]; other site
882884002959	Walker B motif; other site
882884002960	arginine finger; other site
882884002961	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
882884002962	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
882884002963	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
882884002964	ABC-ATPase subunit  interface; other site
882884002965	dimer interface [polypeptide binding]; other site
882884002966	putative PBP binding regions; other site
882884002967	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
882884002968	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
882884002969	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
882884002970	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
882884002971	metal binding site [ion binding]; metal-binding site
882884002972	putative peptidase; Provisional; Region: PRK11649
882884002973	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
882884002974	Peptidase family M23; Region: Peptidase_M23; pfam01551
882884002975	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
882884002976	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
882884002977	putative acyl-acceptor binding pocket; other site
882884002978	pyruvate kinase; Provisional; Region: PRK05826
882884002979	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
882884002980	domain interfaces; other site
882884002981	active site
882884002982	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
882884002983	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
882884002984	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
882884002985	putative active site [active]
882884002986	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
882884002987	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
882884002988	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
882884002989	phosphogluconate dehydratase; Validated; Region: PRK09054
882884002990	6-phosphogluconate dehydratase; Region: edd; TIGR01196
882884002991	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
882884002992	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
882884002993	active site
882884002994	intersubunit interface [polypeptide binding]; other site
882884002995	catalytic residue [active]
882884002996	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
882884002997	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
882884002998	ATP-grasp domain; Region: ATP-grasp; pfam02222
882884002999	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
882884003000	hypothetical protein; Provisional; Region: PRK13680
882884003001	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
882884003002	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
882884003003	putative metal binding site [ion binding]; other site
882884003004	protease 2; Provisional; Region: PRK10115
882884003005	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
882884003006	exodeoxyribonuclease X; Provisional; Region: PRK07983
882884003007	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
882884003008	active site
882884003009	catalytic site [active]
882884003010	substrate binding site [chemical binding]; other site
882884003011	Predicted amidohydrolase [General function prediction only]; Region: COG0388
882884003012	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
882884003013	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
882884003014	hypothetical protein; Provisional; Region: PRK10301
882884003015	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
882884003016	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
882884003017	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884003018	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
882884003019	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
882884003020	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
882884003021	DinI-like family; Region: DinI; cl11630
882884003022	type III secretion protein SopE2; Provisional; Region: PRK15280
882884003023	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
882884003024	SopE GEF domain; Region: SopE_GEF; pfam07487
882884003025	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
882884003026	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
882884003027	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
882884003028	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
882884003029	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
882884003030	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
882884003031	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
882884003032	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
882884003033	mce related protein; Region: MCE; pfam02470
882884003034	mce related protein; Region: MCE; pfam02470
882884003035	mce related protein; Region: MCE; pfam02470
882884003036	mce related protein; Region: MCE; pfam02470
882884003037	mce related protein; Region: MCE; pfam02470
882884003038	mce related protein; Region: MCE; pfam02470
882884003039	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
882884003040	Paraquat-inducible protein A; Region: PqiA; pfam04403
882884003041	Paraquat-inducible protein A; Region: PqiA; pfam04403
882884003042	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
882884003043	GAF domain; Region: GAF_2; pfam13185
882884003044	ProP expression regulator; Provisional; Region: PRK04950
882884003045	ProQ/FINO family; Region: ProQ; pfam04352
882884003046	carboxy-terminal protease; Provisional; Region: PRK11186
882884003047	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
882884003048	protein binding site [polypeptide binding]; other site
882884003049	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
882884003050	Catalytic dyad [active]
882884003051	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
882884003052	heat shock protein HtpX; Provisional; Region: PRK05457
882884003053	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884003054	Major Facilitator Superfamily; Region: MFS_1; pfam07690
882884003055	putative substrate translocation pore; other site
882884003056	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884003057	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
882884003058	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
882884003059	dimerization interface [polypeptide binding]; other site
882884003060	putative Zn2+ binding site [ion binding]; other site
882884003061	putative DNA binding site [nucleotide binding]; other site
882884003062	Bacterial transcriptional regulator; Region: IclR; pfam01614
882884003063	YobH-like protein; Region: YobH; pfam13996
882884003064	PhoPQ regulatory protein; Provisional; Region: PRK10299
882884003065	YebO-like protein; Region: YebO; pfam13974
882884003066	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
882884003067	DNA-binding site [nucleotide binding]; DNA binding site
882884003068	RNA-binding motif; other site
882884003069	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
882884003070	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
882884003071	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
882884003072	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
882884003073	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884003074	S-adenosylmethionine binding site [chemical binding]; other site
882884003075	hypothetical protein; Provisional; Region: PRK11469
882884003076	Domain of unknown function DUF; Region: DUF204; pfam02659
882884003077	Domain of unknown function DUF; Region: DUF204; pfam02659
882884003078	yybp-ykoy leader
882884003079	hypothetical protein; Provisional; Region: PRK02913
882884003080	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
882884003081	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
882884003082	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
882884003083	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
882884003084	active pocket/dimerization site; other site
882884003085	active site
882884003086	phosphorylation site [posttranslational modification]
882884003087	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
882884003088	active site
882884003089	phosphorylation site [posttranslational modification]
882884003090	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
882884003091	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
882884003092	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
882884003093	Transporter associated domain; Region: CorC_HlyC; smart01091
882884003094	phage resistance protein; Provisional; Region: PRK10551
882884003095	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
882884003096	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
882884003097	L-serine deaminase; Provisional; Region: PRK15023
882884003098	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
882884003099	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
882884003100	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
882884003101	putative active site [active]
882884003102	putative CoA binding site [chemical binding]; other site
882884003103	nudix motif; other site
882884003104	metal binding site [ion binding]; metal-binding site
882884003105	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
882884003106	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
882884003107	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
882884003108	hypothetical protein; Provisional; Region: PRK05114
882884003109	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
882884003110	homotrimer interaction site [polypeptide binding]; other site
882884003111	putative active site [active]
882884003112	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
882884003113	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
882884003114	DEAD_2; Region: DEAD_2; pfam06733
882884003115	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
882884003116	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
882884003117	Glycoprotease family; Region: Peptidase_M22; pfam00814
882884003118	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
882884003119	ribonuclease D; Provisional; Region: PRK10829
882884003120	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
882884003121	catalytic site [active]
882884003122	putative active site [active]
882884003123	putative substrate binding site [chemical binding]; other site
882884003124	HRDC domain; Region: HRDC; cl02578
882884003125	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
882884003126	cell division inhibitor MinD; Provisional; Region: PRK10818
882884003127	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
882884003128	Switch I; other site
882884003129	Switch II; other site
882884003130	septum formation inhibitor; Reviewed; Region: minC; PRK03511
882884003131	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
882884003132	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
882884003133	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
882884003134	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
882884003135	hypothetical protein; Provisional; Region: PRK10691
882884003136	hypothetical protein; Provisional; Region: PRK05170
882884003137	GnsA/GnsB family; Region: GnsAB; pfam08178
882884003138	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
882884003139	disulfide bond formation protein B; Provisional; Region: PRK01749
882884003140	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
882884003141	transmembrane helices; other site
882884003142	fatty acid metabolism regulator; Provisional; Region: PRK04984
882884003143	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884003144	DNA-binding site [nucleotide binding]; DNA binding site
882884003145	FadR C-terminal domain; Region: FadR_C; pfam07840
882884003146	SpoVR family protein; Provisional; Region: PRK11767
882884003147	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
882884003148	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
882884003149	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
882884003150	alanine racemase; Reviewed; Region: dadX; PRK03646
882884003151	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
882884003152	active site
882884003153	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
882884003154	substrate binding site [chemical binding]; other site
882884003155	catalytic residues [active]
882884003156	dimer interface [polypeptide binding]; other site
882884003157	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
882884003158	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
882884003159	TrkA-C domain; Region: TrkA_C; pfam02080
882884003160	Transporter associated domain; Region: CorC_HlyC; smart01091
882884003161	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
882884003162	dimer interface [polypeptide binding]; other site
882884003163	catalytic triad [active]
882884003164	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
882884003165	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
882884003166	N-acetyl-D-glucosamine binding site [chemical binding]; other site
882884003167	catalytic residue [active]
882884003168	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
882884003169	Flagellar regulator YcgR; Region: YcgR; pfam07317
882884003170	PilZ domain; Region: PilZ; pfam07238
882884003171	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
882884003172	trehalase; Provisional; Region: treA; PRK13271
882884003173	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
882884003174	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
882884003175	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
882884003176	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
882884003177	NAD(P) binding site [chemical binding]; other site
882884003178	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
882884003179	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
882884003180	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
882884003181	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
882884003182	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
882884003183	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
882884003184	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
882884003185	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
882884003186	putative substrate-binding site; other site
882884003187	nickel binding site [ion binding]; other site
882884003188	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
882884003189	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
882884003190	hydrogenase 1 large subunit; Provisional; Region: PRK10170
882884003191	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
882884003192	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
882884003193	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
882884003194	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
882884003195	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884003196	Sulfatase; Region: Sulfatase; cl17466
882884003197	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
882884003198	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
882884003199	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884003200	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
882884003201	active site
882884003202	phosphorylation site [posttranslational modification]
882884003203	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
882884003204	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
882884003205	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
882884003206	active pocket/dimerization site; other site
882884003207	active site
882884003208	phosphorylation site [posttranslational modification]
882884003209	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
882884003210	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
882884003211	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884003212	FeS/SAM binding site; other site
882884003213	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
882884003214	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884003215	Sulfatase; Region: Sulfatase; pfam00884
882884003216	Uncharacterized protein conserved in bacteria (DUF2264); Region: DUF2264; cl01752
882884003217	GTP-binding protein YchF; Reviewed; Region: PRK09601
882884003218	YchF GTPase; Region: YchF; cd01900
882884003219	G1 box; other site
882884003220	GTP/Mg2+ binding site [chemical binding]; other site
882884003221	Switch I region; other site
882884003222	G2 box; other site
882884003223	Switch II region; other site
882884003224	G3 box; other site
882884003225	G4 box; other site
882884003226	G5 box; other site
882884003227	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
882884003228	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
882884003229	putative active site [active]
882884003230	catalytic residue [active]
882884003231	hypothetical protein; Provisional; Region: PRK10692
882884003232	putative transporter; Provisional; Region: PRK11660
882884003233	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
882884003234	Sulfate transporter family; Region: Sulfate_transp; pfam00916
882884003235	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
882884003236	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
882884003237	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
882884003238	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
882884003239	active site
882884003240	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
882884003241	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
882884003242	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
882884003243	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
882884003244	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
882884003245	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
882884003246	tRNA; other site
882884003247	putative tRNA binding site [nucleotide binding]; other site
882884003248	putative NADP binding site [chemical binding]; other site
882884003249	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
882884003250	peptide chain release factor 1; Validated; Region: prfA; PRK00591
882884003251	This domain is found in peptide chain release factors; Region: PCRF; smart00937
882884003252	RF-1 domain; Region: RF-1; pfam00472
882884003253	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
882884003254	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884003255	hypothetical protein; Provisional; Region: PRK10278
882884003256	hypothetical protein; Provisional; Region: PRK10941
882884003257	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
882884003258	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
882884003259	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
882884003260	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
882884003261	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
882884003262	cation transport regulator; Reviewed; Region: chaB; PRK09582
882884003263	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
882884003264	putative invasin; Provisional; Region: PRK10177
882884003265	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
882884003266	transcriptional regulator NarL; Provisional; Region: PRK10651
882884003267	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884003268	active site
882884003269	phosphorylation site [posttranslational modification]
882884003270	intermolecular recognition site; other site
882884003271	dimerization interface [polypeptide binding]; other site
882884003272	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884003273	DNA binding residues [nucleotide binding]
882884003274	dimerization interface [polypeptide binding]; other site
882884003275	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
882884003276	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
882884003277	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884003278	dimerization interface [polypeptide binding]; other site
882884003279	Histidine kinase; Region: HisKA_3; pfam07730
882884003280	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884003281	ATP binding site [chemical binding]; other site
882884003282	Mg2+ binding site [ion binding]; other site
882884003283	G-X-G motif; other site
882884003284	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
882884003285	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
882884003286	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
882884003287	[4Fe-4S] binding site [ion binding]; other site
882884003288	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
882884003289	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
882884003290	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
882884003291	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
882884003292	molybdopterin cofactor binding site; other site
882884003293	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
882884003294	4Fe-4S binding domain; Region: Fer4; cl02805
882884003295	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
882884003296	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
882884003297	RtT RNA; Rfam score 145.46; SARI_01194
882884003298	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
882884003299	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
882884003300	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
882884003301	putative active site [active]
882884003302	putative substrate binding site [chemical binding]; other site
882884003303	putative cosubstrate binding site; other site
882884003304	catalytic site [active]
882884003305	hypothetical protein; Provisional; Region: PRK01617
882884003306	hypothetical protein; Provisional; Region: PRK10279
882884003307	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
882884003308	active site
882884003309	nucleophile elbow; other site
882884003310	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884003311	active site
882884003312	response regulator of RpoS; Provisional; Region: PRK10693
882884003313	phosphorylation site [posttranslational modification]
882884003314	intermolecular recognition site; other site
882884003315	dimerization interface [polypeptide binding]; other site
882884003316	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
882884003317	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
882884003318	active site
882884003319	tetramer interface; other site
882884003320	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
882884003321	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
882884003322	thymidine kinase; Provisional; Region: PRK04296
882884003323	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
882884003324	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
882884003325	putative catalytic cysteine [active]
882884003326	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
882884003327	putative active site [active]
882884003328	metal binding site [ion binding]; metal-binding site
882884003329	hypothetical protein; Provisional; Region: PRK11111
882884003330	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
882884003331	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
882884003332	peptide binding site [polypeptide binding]; other site
882884003333	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
882884003334	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884003335	dimer interface [polypeptide binding]; other site
882884003336	conserved gate region; other site
882884003337	putative PBP binding loops; other site
882884003338	ABC-ATPase subunit interface; other site
882884003339	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
882884003340	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
882884003341	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884003342	dimer interface [polypeptide binding]; other site
882884003343	conserved gate region; other site
882884003344	ABC-ATPase subunit interface; other site
882884003345	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
882884003346	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884003347	Walker A/P-loop; other site
882884003348	ATP binding site [chemical binding]; other site
882884003349	Q-loop/lid; other site
882884003350	ABC transporter signature motif; other site
882884003351	Walker B; other site
882884003352	D-loop; other site
882884003353	H-loop/switch region; other site
882884003354	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
882884003355	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
882884003356	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884003357	Walker A/P-loop; other site
882884003358	ATP binding site [chemical binding]; other site
882884003359	Q-loop/lid; other site
882884003360	ABC transporter signature motif; other site
882884003361	Walker B; other site
882884003362	D-loop; other site
882884003363	H-loop/switch region; other site
882884003364	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
882884003365	Ion transport protein; Region: Ion_trans; pfam00520
882884003366	Ion channel; Region: Ion_trans_2; pfam07885
882884003367	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
882884003368	Double zinc ribbon; Region: DZR; pfam12773
882884003369	dsDNA-mimic protein; Reviewed; Region: PRK05094
882884003370	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
882884003371	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
882884003372	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
882884003373	putative active site [active]
882884003374	catalytic site [active]
882884003375	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
882884003376	putative active site [active]
882884003377	catalytic site [active]
882884003378	YciI-like protein; Reviewed; Region: PRK11370
882884003379	transport protein TonB; Provisional; Region: PRK10819
882884003380	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
882884003381	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
882884003382	intracellular septation protein A; Reviewed; Region: PRK00259
882884003383	hypothetical protein; Provisional; Region: PRK02868
882884003384	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
882884003385	outer membrane protein W; Provisional; Region: PRK10959
882884003386	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
882884003387	dimanganese center [ion binding]; other site
882884003388	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
882884003389	dinuclear metal binding motif [ion binding]; other site
882884003390	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
882884003391	dimerization interface [polypeptide binding]; other site
882884003392	metal binding site [ion binding]; metal-binding site
882884003393	General stress protein [General function prediction only]; Region: GsiB; COG3729
882884003394	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
882884003395	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
882884003396	substrate binding site [chemical binding]; other site
882884003397	active site
882884003398	catalytic residues [active]
882884003399	heterodimer interface [polypeptide binding]; other site
882884003400	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
882884003401	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
882884003402	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884003403	catalytic residue [active]
882884003404	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
882884003405	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
882884003406	active site
882884003407	ribulose/triose binding site [chemical binding]; other site
882884003408	phosphate binding site [ion binding]; other site
882884003409	substrate (anthranilate) binding pocket [chemical binding]; other site
882884003410	product (indole) binding pocket [chemical binding]; other site
882884003411	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
882884003412	active site
882884003413	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
882884003414	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
882884003415	glutamine binding [chemical binding]; other site
882884003416	catalytic triad [active]
882884003417	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
882884003418	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
882884003419	anthranilate synthase component I; Provisional; Region: PRK13564
882884003420	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
882884003421	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
882884003422	tryptophan operon leader
882884003423	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
882884003424	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
882884003425	active site
882884003426	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
882884003427	hypothetical protein; Provisional; Region: PRK11630
882884003428	Integrase core domain; Region: rve; pfam00665
882884003429	Integrase core domain; Region: rve_3; pfam13683
882884003430	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
882884003431	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
882884003432	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
882884003433	RNA binding surface [nucleotide binding]; other site
882884003434	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
882884003435	probable active site [active]
882884003436	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
882884003437	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
882884003438	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
882884003439	homodimer interface [polypeptide binding]; other site
882884003440	Walker A motif; other site
882884003441	ATP binding site [chemical binding]; other site
882884003442	hydroxycobalamin binding site [chemical binding]; other site
882884003443	Walker B motif; other site
882884003444	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
882884003445	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
882884003446	NADP binding site [chemical binding]; other site
882884003447	homodimer interface [polypeptide binding]; other site
882884003448	active site
882884003449	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
882884003450	putative inner membrane peptidase; Provisional; Region: PRK11778
882884003451	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
882884003452	tandem repeat interface [polypeptide binding]; other site
882884003453	oligomer interface [polypeptide binding]; other site
882884003454	active site residues [active]
882884003455	hypothetical protein; Provisional; Region: PRK11037
882884003456	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
882884003457	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
882884003458	active site
882884003459	interdomain interaction site; other site
882884003460	putative metal-binding site [ion binding]; other site
882884003461	nucleotide binding site [chemical binding]; other site
882884003462	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
882884003463	domain I; other site
882884003464	DNA binding groove [nucleotide binding]
882884003465	phosphate binding site [ion binding]; other site
882884003466	domain II; other site
882884003467	domain III; other site
882884003468	nucleotide binding site [chemical binding]; other site
882884003469	catalytic site [active]
882884003470	domain IV; other site
882884003471	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
882884003472	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
882884003473	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
882884003474	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
882884003475	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
882884003476	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884003477	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
882884003478	substrate binding site [chemical binding]; other site
882884003479	putative dimerization interface [polypeptide binding]; other site
882884003480	aconitate hydratase; Validated; Region: PRK09277
882884003481	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
882884003482	substrate binding site [chemical binding]; other site
882884003483	ligand binding site [chemical binding]; other site
882884003484	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
882884003485	substrate binding site [chemical binding]; other site
882884003486	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
882884003487	dimerization interface [polypeptide binding]; other site
882884003488	active site
882884003489	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
882884003490	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
882884003491	active site
882884003492	Predicted membrane protein [Function unknown]; Region: COG3771
882884003493	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
882884003494	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
882884003495	TPR motif; other site
882884003496	binding surface
882884003497	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
882884003498	binding surface
882884003499	TPR motif; other site
882884003500	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
882884003501	active site
882884003502	dimer interface [polypeptide binding]; other site
882884003503	translation initiation factor Sui1; Validated; Region: PRK06824
882884003504	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
882884003505	putative rRNA binding site [nucleotide binding]; other site
882884003506	lipoprotein; Provisional; Region: PRK10540
882884003507	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
882884003508	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
882884003509	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884003510	hypothetical protein; Provisional; Region: PRK13658
882884003511	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
882884003512	RNase II stability modulator; Provisional; Region: PRK10060
882884003513	exoribonuclease II; Provisional; Region: PRK05054
882884003514	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
882884003515	RNB domain; Region: RNB; pfam00773
882884003516	S1 RNA binding domain; Region: S1; pfam00575
882884003517	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
882884003518	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
882884003519	NAD binding site [chemical binding]; other site
882884003520	homotetramer interface [polypeptide binding]; other site
882884003521	homodimer interface [polypeptide binding]; other site
882884003522	substrate binding site [chemical binding]; other site
882884003523	active site
882884003524	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
882884003525	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
882884003526	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884003527	Walker A/P-loop; other site
882884003528	ATP binding site [chemical binding]; other site
882884003529	Q-loop/lid; other site
882884003530	ABC transporter signature motif; other site
882884003531	Walker B; other site
882884003532	D-loop; other site
882884003533	H-loop/switch region; other site
882884003534	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
882884003535	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884003536	Walker A/P-loop; other site
882884003537	ATP binding site [chemical binding]; other site
882884003538	Q-loop/lid; other site
882884003539	ABC transporter signature motif; other site
882884003540	Walker B; other site
882884003541	D-loop; other site
882884003542	H-loop/switch region; other site
882884003543	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
882884003544	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
882884003545	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
882884003546	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884003547	dimer interface [polypeptide binding]; other site
882884003548	conserved gate region; other site
882884003549	putative PBP binding loops; other site
882884003550	ABC-ATPase subunit interface; other site
882884003551	Integrase core domain; Region: rve_3; cl15866
882884003552	HTH-like domain; Region: HTH_21; pfam13276
882884003553	Integrase core domain; Region: rve; pfam00665
882884003554	Transposase; Region: DEDD_Tnp_IS110; pfam01548
882884003555	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884003556	Transposase; Region: HTH_Tnp_1; pfam01527
882884003557	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
882884003558	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
882884003559	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
882884003560	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
882884003561	DNA-binding interface [nucleotide binding]; DNA binding site
882884003562	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
882884003563	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884003564	dimer interface [polypeptide binding]; other site
882884003565	conserved gate region; other site
882884003566	putative PBP binding loops; other site
882884003567	ABC-ATPase subunit interface; other site
882884003568	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
882884003569	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
882884003570	peptide binding site [polypeptide binding]; other site
882884003571	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
882884003572	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884003573	Walker A motif; other site
882884003574	ATP binding site [chemical binding]; other site
882884003575	Walker B motif; other site
882884003576	arginine finger; other site
882884003577	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
882884003578	phage shock protein PspA; Provisional; Region: PRK10698
882884003579	phage shock protein B; Provisional; Region: pspB; PRK09458
882884003580	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
882884003581	phage shock protein C; Region: phageshock_pspC; TIGR02978
882884003582	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
882884003583	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
882884003584	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
882884003585	active site
882884003586	homodimer interface [polypeptide binding]; other site
882884003587	catalytic site [active]
882884003588	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
882884003589	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
882884003590	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884003591	dimer interface [polypeptide binding]; other site
882884003592	conserved gate region; other site
882884003593	putative PBP binding loops; other site
882884003594	ABC-ATPase subunit interface; other site
882884003595	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
882884003596	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884003597	dimer interface [polypeptide binding]; other site
882884003598	conserved gate region; other site
882884003599	putative PBP binding loops; other site
882884003600	ABC-ATPase subunit interface; other site
882884003601	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
882884003602	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
882884003603	putative NAD(P) binding site [chemical binding]; other site
882884003604	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
882884003605	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
882884003606	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
882884003607	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
882884003608	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
882884003609	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
882884003610	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
882884003611	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
882884003612	beta-phosphoglucomutase; Region: bPGM; TIGR01990
882884003613	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884003614	motif II; other site
882884003615	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
882884003616	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
882884003617	Walker A/P-loop; other site
882884003618	ATP binding site [chemical binding]; other site
882884003619	Q-loop/lid; other site
882884003620	ABC transporter signature motif; other site
882884003621	Walker B; other site
882884003622	D-loop; other site
882884003623	H-loop/switch region; other site
882884003624	TOBE domain; Region: TOBE_2; pfam08402
882884003625	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
882884003626	Transcriptional regulators [Transcription]; Region: PurR; COG1609
882884003627	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884003628	DNA binding site [nucleotide binding]
882884003629	domain linker motif; other site
882884003630	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
882884003631	putative dimerization interface [polypeptide binding]; other site
882884003632	putative ligand binding site [chemical binding]; other site
882884003633	Predicted ATPase [General function prediction only]; Region: COG3106
882884003634	hypothetical protein; Provisional; Region: PRK05415
882884003635	TIGR01620 family protein; Region: hyp_HI0043
882884003636	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
882884003637	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
882884003638	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884003639	Walker A motif; other site
882884003640	ATP binding site [chemical binding]; other site
882884003641	Walker B motif; other site
882884003642	arginine finger; other site
882884003643	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
882884003644	dimer interface [polypeptide binding]; other site
882884003645	catalytic triad [active]
882884003646	peroxidatic and resolving cysteines [active]
882884003647	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
882884003648	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
882884003649	active site
882884003650	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
882884003651	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
882884003652	putative active site [active]
882884003653	Zn binding site [ion binding]; other site
882884003654	Cytolethal distending toxin A/C family; Region: CDtoxinA; pfam03498
882884003655	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cl15820
882884003656	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
882884003657	putative catalytic site [active]
882884003658	putative phosphate binding site [ion binding]; other site
882884003659	putative metal binding site [ion binding]; other site
882884003660	Cytolethal distending toxin A/C family; Region: CDtoxinA; pfam03498
882884003661	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
882884003662	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
882884003663	peptide binding site [polypeptide binding]; other site
882884003664	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
882884003665	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
882884003666	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
882884003667	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884003668	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
882884003669	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
882884003670	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
882884003671	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
882884003672	B3/4 domain; Region: B3_4; pfam03483
882884003673	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884003674	non-specific DNA binding site [nucleotide binding]; other site
882884003675	salt bridge; other site
882884003676	sequence-specific DNA binding site [nucleotide binding]; other site
882884003677	Cupin domain; Region: Cupin_2; pfam07883
882884003678	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
882884003679	Mechanosensitive ion channel; Region: MS_channel; pfam00924
882884003680	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
882884003681	universal stress protein UspE; Provisional; Region: PRK11175
882884003682	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
882884003683	Ligand Binding Site [chemical binding]; other site
882884003684	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
882884003685	Ligand Binding Site [chemical binding]; other site
882884003686	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
882884003687	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
882884003688	ligand binding site [chemical binding]; other site
882884003689	flexible hinge region; other site
882884003690	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
882884003691	putative switch regulator; other site
882884003692	non-specific DNA interactions [nucleotide binding]; other site
882884003693	DNA binding site [nucleotide binding]
882884003694	sequence specific DNA binding site [nucleotide binding]; other site
882884003695	putative cAMP binding site [chemical binding]; other site
882884003696	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
882884003697	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
882884003698	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
882884003699	DNA binding site [nucleotide binding]
882884003700	active site
882884003701	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
882884003702	Smr domain; Region: Smr; pfam01713
882884003703	HAMP domain; Region: HAMP; pfam00672
882884003704	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
882884003705	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
882884003706	dimer interface [polypeptide binding]; other site
882884003707	putative CheW interface [polypeptide binding]; other site
882884003708	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
882884003709	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
882884003710	Cl binding site [ion binding]; other site
882884003711	oligomer interface [polypeptide binding]; other site
882884003712	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
882884003713	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
882884003714	ATP binding site [chemical binding]; other site
882884003715	Mg++ binding site [ion binding]; other site
882884003716	motif III; other site
882884003717	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884003718	nucleotide binding region [chemical binding]; other site
882884003719	ATP-binding site [chemical binding]; other site
882884003720	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
882884003721	putative RNA binding site [nucleotide binding]; other site
882884003722	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
882884003723	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
882884003724	Ligand Binding Site [chemical binding]; other site
882884003725	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
882884003726	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
882884003727	Ligand Binding Site [chemical binding]; other site
882884003728	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
882884003729	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
882884003730	dimer interface [polypeptide binding]; other site
882884003731	PYR/PP interface [polypeptide binding]; other site
882884003732	TPP binding site [chemical binding]; other site
882884003733	substrate binding site [chemical binding]; other site
882884003734	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
882884003735	Domain of unknown function; Region: EKR; smart00890
882884003736	4Fe-4S binding domain; Region: Fer4_6; pfam12837
882884003737	4Fe-4S binding domain; Region: Fer4; pfam00037
882884003738	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
882884003739	TPP-binding site [chemical binding]; other site
882884003740	dimer interface [polypeptide binding]; other site
882884003741	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
882884003742	Domain of unknown function (DUF333); Region: DUF333; pfam03891
882884003743	heat-inducible protein; Provisional; Region: PRK10449
882884003744	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
882884003745	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
882884003746	putative ligand binding site [chemical binding]; other site
882884003747	putative NAD binding site [chemical binding]; other site
882884003748	catalytic site [active]
882884003749	hypothetical protein; Provisional; Region: PRK10695
882884003750	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
882884003751	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
882884003752	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
882884003753	Cytidylyltransferase family; Region: CTP_transf_1; cl17467
882884003754	Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; cl01553
882884003755	azoreductase; Reviewed; Region: PRK00170
882884003756	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
882884003757	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
882884003758	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884003759	ATP binding site [chemical binding]; other site
882884003760	putative Mg++ binding site [ion binding]; other site
882884003761	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884003762	nucleotide binding region [chemical binding]; other site
882884003763	ATP-binding site [chemical binding]; other site
882884003764	Helicase associated domain (HA2); Region: HA2; pfam04408
882884003765	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
882884003766	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
882884003767	Uncharacterized conserved protein [Function unknown]; Region: COG1434
882884003768	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
882884003769	putative active site [active]
882884003770	cytochrome b561; Provisional; Region: PRK11513
882884003771	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
882884003772	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884003773	S-adenosylmethionine binding site [chemical binding]; other site
882884003774	Sif protein; Region: Sif; cl11505
882884003775	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
882884003776	active site
882884003777	catalytic triad [active]
882884003778	oxyanion hole [active]
882884003779	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
882884003780	putative metal binding site [ion binding]; other site
882884003781	putative homodimer interface [polypeptide binding]; other site
882884003782	putative homotetramer interface [polypeptide binding]; other site
882884003783	putative homodimer-homodimer interface [polypeptide binding]; other site
882884003784	putative allosteric switch controlling residues; other site
882884003785	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
882884003786	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
882884003787	substrate binding site [chemical binding]; other site
882884003788	catalytic Zn binding site [ion binding]; other site
882884003789	NAD binding site [chemical binding]; other site
882884003790	structural Zn binding site [ion binding]; other site
882884003791	dimer interface [polypeptide binding]; other site
882884003792	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
882884003793	dimer interface [polypeptide binding]; other site
882884003794	ligand binding site [chemical binding]; other site
882884003795	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
882884003796	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884003797	dimerization interface [polypeptide binding]; other site
882884003798	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
882884003799	dimer interface [polypeptide binding]; other site
882884003800	putative CheW interface [polypeptide binding]; other site
882884003801	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
882884003802	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884003803	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884003804	dimerization interface [polypeptide binding]; other site
882884003805	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
882884003806	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
882884003807	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
882884003808	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
882884003809	substrate binding pocket [chemical binding]; other site
882884003810	catalytic triad [active]
882884003811	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
882884003812	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
882884003813	Protein of unknown function (DUF796); Region: DUF796; cl01226
882884003814	M42 glutamyl aminopeptidase; Region: Peptidase_M42; cl17262
882884003815	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
882884003816	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
882884003817	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884003818	Coenzyme A binding pocket [chemical binding]; other site
882884003819	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
882884003820	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
882884003821	gating phenylalanine in ion channel; other site
882884003822	tellurite resistance protein TehB; Provisional; Region: PRK11207
882884003823	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884003824	S-adenosylmethionine binding site [chemical binding]; other site
882884003825	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
882884003826	benzoate transporter; Region: benE; TIGR00843
882884003827	Cupin domain; Region: Cupin_2; pfam07883
882884003828	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
882884003829	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
882884003830	Peptidase family U32; Region: Peptidase_U32; pfam01136
882884003831	Collagenase; Region: DUF3656; pfam12392
882884003832	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
882884003833	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
882884003834	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
882884003835	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
882884003836	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884003837	DNA-binding site [nucleotide binding]; DNA binding site
882884003838	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884003839	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884003840	homodimer interface [polypeptide binding]; other site
882884003841	catalytic residue [active]
882884003842	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
882884003843	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
882884003844	tetrameric interface [polypeptide binding]; other site
882884003845	NAD binding site [chemical binding]; other site
882884003846	catalytic residues [active]
882884003847	substrate binding site [chemical binding]; other site
882884003848	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
882884003849	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
882884003850	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
882884003851	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
882884003852	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
882884003853	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
882884003854	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
882884003855	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
882884003856	Prostaglandin dehydrogenases; Region: PGDH; cd05288
882884003857	NAD(P) binding site [chemical binding]; other site
882884003858	substrate binding site [chemical binding]; other site
882884003859	dimer interface [polypeptide binding]; other site
882884003860	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
882884003861	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884003862	DNA-binding site [nucleotide binding]; DNA binding site
882884003863	FCD domain; Region: FCD; pfam07729
882884003864	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
882884003865	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
882884003866	N-terminal plug; other site
882884003867	ligand-binding site [chemical binding]; other site
882884003868	Uncharacterized conserved protein [Function unknown]; Region: COG3391
882884003869	TetR family transcriptional regulator; Provisional; Region: PRK14996
882884003870	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884003871	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
882884003872	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884003873	putative substrate translocation pore; other site
882884003874	Uncharacterized conserved protein [Function unknown]; Region: COG3791
882884003875	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
882884003876	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
882884003877	trimer interface [polypeptide binding]; other site
882884003878	eyelet of channel; other site
882884003879	aromatic amino acid exporter; Provisional; Region: PRK11689
882884003880	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
882884003881	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
882884003882	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
882884003883	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
882884003884	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
882884003885	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
882884003886	NAD binding site [chemical binding]; other site
882884003887	substrate binding site [chemical binding]; other site
882884003888	catalytic Zn binding site [ion binding]; other site
882884003889	tetramer interface [polypeptide binding]; other site
882884003890	structural Zn binding site [ion binding]; other site
882884003891	malate dehydrogenase; Provisional; Region: PRK13529
882884003892	Malic enzyme, N-terminal domain; Region: malic; pfam00390
882884003893	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
882884003894	NAD(P) binding site [chemical binding]; other site
882884003895	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
882884003896	biofilm-dependent modulation protein; Provisional; Region: PRK11436
882884003897	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
882884003898	acid-resistance protein; Provisional; Region: hdeB; PRK11566
882884003899	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
882884003900	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
882884003901	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
882884003902	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
882884003903	catalytic site [active]
882884003904	active site
882884003905	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
882884003906	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
882884003907	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
882884003908	active site
882884003909	catalytic site [active]
882884003910	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
882884003911	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
882884003912	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
882884003913	active site
882884003914	catalytic site [active]
882884003915	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
882884003916	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884003917	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884003918	homodimer interface [polypeptide binding]; other site
882884003919	catalytic residue [active]
882884003920	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
882884003921	Transcriptional regulators [Transcription]; Region: PurR; COG1609
882884003922	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884003923	DNA binding site [nucleotide binding]
882884003924	domain linker motif; other site
882884003925	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
882884003926	dimerization interface (closed form) [polypeptide binding]; other site
882884003927	ligand binding site [chemical binding]; other site
882884003928	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
882884003929	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
882884003930	Restriction endonuclease; Region: Mrr_cat; pfam04471
882884003931	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
882884003932	HsdM N-terminal domain; Region: HsdM_N; pfam12161
882884003933	Methyltransferase domain; Region: Methyltransf_26; pfam13659
882884003934	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
882884003935	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
882884003936	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
882884003937	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
882884003938	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884003939	ATP binding site [chemical binding]; other site
882884003940	putative Mg++ binding site [ion binding]; other site
882884003941	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
882884003942	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
882884003943	Walker A/P-loop; other site
882884003944	ATP binding site [chemical binding]; other site
882884003945	Q-loop/lid; other site
882884003946	ABC transporter signature motif; other site
882884003947	Walker B; other site
882884003948	D-loop; other site
882884003949	H-loop/switch region; other site
882884003950	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
882884003951	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884003952	dimer interface [polypeptide binding]; other site
882884003953	conserved gate region; other site
882884003954	ABC-ATPase subunit interface; other site
882884003955	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
882884003956	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884003957	dimer interface [polypeptide binding]; other site
882884003958	conserved gate region; other site
882884003959	putative PBP binding loops; other site
882884003960	ABC-ATPase subunit interface; other site
882884003961	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
882884003962	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
882884003963	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
882884003964	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
882884003965	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
882884003966	putative [Fe4-S4] binding site [ion binding]; other site
882884003967	putative molybdopterin cofactor binding site [chemical binding]; other site
882884003968	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
882884003969	putative molybdopterin cofactor binding site; other site
882884003970	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
882884003971	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
882884003972	putative [Fe4-S4] binding site [ion binding]; other site
882884003973	putative molybdopterin cofactor binding site [chemical binding]; other site
882884003974	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
882884003975	putative molybdopterin cofactor binding site; other site
882884003976	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
882884003977	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
882884003978	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
882884003979	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884003980	Coenzyme A binding pocket [chemical binding]; other site
882884003981	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
882884003982	hypothetical protein; Provisional; Region: PRK13659
882884003983	hypothetical protein; Provisional; Region: PRK02237
882884003984	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
882884003985	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
882884003986	putative active site pocket [active]
882884003987	putative metal binding site [ion binding]; other site
882884003988	putative oxidoreductase; Provisional; Region: PRK10083
882884003989	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
882884003990	putative NAD(P) binding site [chemical binding]; other site
882884003991	catalytic Zn binding site [ion binding]; other site
882884003992	structural Zn binding site [ion binding]; other site
882884003993	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884003994	metabolite-proton symporter; Region: 2A0106; TIGR00883
882884003995	putative substrate translocation pore; other site
882884003996	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
882884003997	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
882884003998	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
882884003999	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
882884004000	Transcriptional regulators [Transcription]; Region: GntR; COG1802
882884004001	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884004002	DNA-binding site [nucleotide binding]; DNA binding site
882884004003	FCD domain; Region: FCD; pfam07729
882884004004	malonic semialdehyde reductase; Provisional; Region: PRK10538
882884004005	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
882884004006	putative NAD(P) binding site [chemical binding]; other site
882884004007	homodimer interface [polypeptide binding]; other site
882884004008	homotetramer interface [polypeptide binding]; other site
882884004009	active site
882884004010	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
882884004011	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
882884004012	active site
882884004013	Zn binding site [ion binding]; other site
882884004014	General stress protein [General function prediction only]; Region: GsiB; COG3729
882884004015	hypothetical protein; Validated; Region: PRK03657
882884004016	hypothetical protein; Provisional; Region: PRK10053
882884004017	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
882884004018	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884004019	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884004020	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
882884004021	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
882884004022	inner membrane protein; Provisional; Region: PRK10995
882884004023	putative arabinose transporter; Provisional; Region: PRK03545
882884004024	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884004025	putative substrate translocation pore; other site
882884004026	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884004027	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884004028	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
882884004029	putative dimerization interface [polypeptide binding]; other site
882884004030	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
882884004031	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
882884004032	NAD(P) binding site [chemical binding]; other site
882884004033	catalytic residues [active]
882884004034	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
882884004035	glutaminase; Provisional; Region: PRK00971
882884004036	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
882884004037	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
882884004038	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
882884004039	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
882884004040	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
882884004041	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
882884004042	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
882884004043	Rubredoxin [Energy production and conversion]; Region: COG1773
882884004044	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
882884004045	iron binding site [ion binding]; other site
882884004046	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
882884004047	HupF/HypC family; Region: HupF_HypC; cl00394
882884004048	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
882884004049	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
882884004050	putative substrate-binding site; other site
882884004051	nickel binding site [ion binding]; other site
882884004052	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
882884004053	hydrogenase 1 large subunit; Provisional; Region: PRK10170
882884004054	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
882884004055	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
882884004056	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
882884004057	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
882884004058	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
882884004059	ProQ/FINO family; Region: ProQ; pfam04352
882884004060	transcriptional regulator SpvR; Provisional; Region: PRK15243
882884004061	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884004062	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884004063	virulence protein SpvA; Provisional; Region: PRK15212
882884004064	virulence protein SpvB; Provisional; Region: PRK15244
882884004065	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
882884004066	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
882884004067	active site
882884004068	conformational flexibility of ligand binding pocket; other site
882884004069	ADP-ribosylating toxin turn-turn motif; other site
882884004070	Salmonella virulence-associated 28kDa protein; Region: VRP3; pfam03536
882884004071	Protein of unknown function DUF45; Region: DUF45; pfam01863
882884004072	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
882884004073	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
882884004074	Cl- selectivity filter; other site
882884004075	Cl- binding residues [ion binding]; other site
882884004076	pore gating glutamate residue; other site
882884004077	dimer interface [polypeptide binding]; other site
882884004078	putative dithiobiotin synthetase; Provisional; Region: PRK12374
882884004079	AAA domain; Region: AAA_26; pfam13500
882884004080	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
882884004081	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
882884004082	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
882884004083	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
882884004084	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884004085	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
882884004086	dimerization interface [polypeptide binding]; other site
882884004087	substrate binding pocket [chemical binding]; other site
882884004088	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
882884004089	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884004090	putative substrate translocation pore; other site
882884004091	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
882884004092	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
882884004093	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
882884004094	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
882884004095	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
882884004096	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
882884004097	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
882884004098	ligand binding site [chemical binding]; other site
882884004099	homodimer interface [polypeptide binding]; other site
882884004100	NAD(P) binding site [chemical binding]; other site
882884004101	trimer interface B [polypeptide binding]; other site
882884004102	trimer interface A [polypeptide binding]; other site
882884004103	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
882884004104	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884004105	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884004106	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884004107	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
882884004108	Spore germination protein; Region: Spore_permease; cl17796
882884004109	GlpM protein; Region: GlpM; pfam06942
882884004110	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
882884004111	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884004112	active site
882884004113	phosphorylation site [posttranslational modification]
882884004114	intermolecular recognition site; other site
882884004115	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884004116	DNA binding site [nucleotide binding]
882884004117	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
882884004118	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
882884004119	trimer interface [polypeptide binding]; other site
882884004120	eyelet of channel; other site
882884004121	sensor protein RstB; Provisional; Region: PRK10604
882884004122	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884004123	dimerization interface [polypeptide binding]; other site
882884004124	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884004125	dimer interface [polypeptide binding]; other site
882884004126	phosphorylation site [posttranslational modification]
882884004127	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884004128	ATP binding site [chemical binding]; other site
882884004129	Mg2+ binding site [ion binding]; other site
882884004130	G-X-G motif; other site
882884004131	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
882884004132	fumarate hydratase; Reviewed; Region: fumC; PRK00485
882884004133	Class II fumarases; Region: Fumarase_classII; cd01362
882884004134	active site
882884004135	tetramer interface [polypeptide binding]; other site
882884004136	fumarate hydratase; Provisional; Region: PRK15389
882884004137	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
882884004138	Fumarase C-terminus; Region: Fumerase_C; pfam05683
882884004139	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
882884004140	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
882884004141	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
882884004142	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
882884004143	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
882884004144	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
882884004145	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884004146	DNA binding site [nucleotide binding]
882884004147	domain linker motif; other site
882884004148	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
882884004149	putative dimerization interface [polypeptide binding]; other site
882884004150	putative ligand binding site [chemical binding]; other site
882884004151	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
882884004152	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
882884004153	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
882884004154	active site turn [active]
882884004155	phosphorylation site [posttranslational modification]
882884004156	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
882884004157	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884004158	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884004159	homodimer interface [polypeptide binding]; other site
882884004160	catalytic residue [active]
882884004161	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
882884004162	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
882884004163	active site
882884004164	purine riboside binding site [chemical binding]; other site
882884004165	putative oxidoreductase; Provisional; Region: PRK11579
882884004166	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
882884004167	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
882884004168	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
882884004169	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
882884004170	electron transport complex protein RsxA; Provisional; Region: PRK05151
882884004171	electron transport complex protein RnfB; Provisional; Region: PRK05113
882884004172	Putative Fe-S cluster; Region: FeS; cl17515
882884004173	4Fe-4S binding domain; Region: Fer4; pfam00037
882884004174	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
882884004175	SLBB domain; Region: SLBB; pfam10531
882884004176	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
882884004177	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
882884004178	electron transport complex protein RnfG; Validated; Region: PRK01908
882884004179	electron transport complex RsxE subunit; Provisional; Region: PRK12405
882884004180	endonuclease III; Provisional; Region: PRK10702
882884004181	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
882884004182	minor groove reading motif; other site
882884004183	helix-hairpin-helix signature motif; other site
882884004184	substrate binding pocket [chemical binding]; other site
882884004185	active site
882884004186	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
882884004187	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
882884004188	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884004189	putative substrate translocation pore; other site
882884004190	POT family; Region: PTR2; pfam00854
882884004191	glutathionine S-transferase; Provisional; Region: PRK10542
882884004192	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
882884004193	C-terminal domain interface [polypeptide binding]; other site
882884004194	GSH binding site (G-site) [chemical binding]; other site
882884004195	dimer interface [polypeptide binding]; other site
882884004196	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
882884004197	dimer interface [polypeptide binding]; other site
882884004198	N-terminal domain interface [polypeptide binding]; other site
882884004199	substrate binding pocket (H-site) [chemical binding]; other site
882884004200	pyridoxamine kinase; Validated; Region: PRK05756
882884004201	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
882884004202	dimer interface [polypeptide binding]; other site
882884004203	pyridoxal binding site [chemical binding]; other site
882884004204	ATP binding site [chemical binding]; other site
882884004205	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
882884004206	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
882884004207	active site
882884004208	HIGH motif; other site
882884004209	dimer interface [polypeptide binding]; other site
882884004210	KMSKS motif; other site
882884004211	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
882884004212	RNA binding surface [nucleotide binding]; other site
882884004213	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
882884004214	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
882884004215	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
882884004216	lysozyme inhibitor; Provisional; Region: PRK11372
882884004217	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
882884004218	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
882884004219	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
882884004220	transcriptional regulator SlyA; Provisional; Region: PRK03573
882884004221	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
882884004222	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
882884004223	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
882884004224	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884004225	Fusaric acid resistance protein family; Region: FUSC; pfam04632
882884004226	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
882884004227	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
882884004228	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
882884004229	E-class dimer interface [polypeptide binding]; other site
882884004230	P-class dimer interface [polypeptide binding]; other site
882884004231	active site
882884004232	Cu2+ binding site [ion binding]; other site
882884004233	Zn2+ binding site [ion binding]; other site
882884004234	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
882884004235	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
882884004236	active site
882884004237	catalytic tetrad [active]
882884004238	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
882884004239	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884004240	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
882884004241	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
882884004242	FMN binding site [chemical binding]; other site
882884004243	active site
882884004244	substrate binding site [chemical binding]; other site
882884004245	catalytic residue [active]
882884004246	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
882884004247	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
882884004248	dimer interface [polypeptide binding]; other site
882884004249	active site
882884004250	glutathione binding site [chemical binding]; other site
882884004251	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
882884004252	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
882884004253	dimer interface [polypeptide binding]; other site
882884004254	catalytic site [active]
882884004255	putative active site [active]
882884004256	putative substrate binding site [chemical binding]; other site
882884004257	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
882884004258	putative GSH binding site [chemical binding]; other site
882884004259	catalytic residues [active]
882884004260	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
882884004261	NlpC/P60 family; Region: NLPC_P60; pfam00877
882884004262	superoxide dismutase; Provisional; Region: PRK10543
882884004263	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
882884004264	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
882884004265	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
882884004266	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884004267	DNA binding site [nucleotide binding]
882884004268	domain linker motif; other site
882884004269	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
882884004270	dimerization interface [polypeptide binding]; other site
882884004271	ligand binding site [chemical binding]; other site
882884004272	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
882884004273	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884004274	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884004275	dimerization interface [polypeptide binding]; other site
882884004276	putative transporter; Provisional; Region: PRK11043
882884004277	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884004278	putative substrate translocation pore; other site
882884004279	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
882884004280	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
882884004281	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884004282	S-adenosylmethionine binding site [chemical binding]; other site
882884004283	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
882884004284	Lumazine binding domain; Region: Lum_binding; pfam00677
882884004285	Lumazine binding domain; Region: Lum_binding; pfam00677
882884004286	multidrug efflux protein; Reviewed; Region: PRK01766
882884004287	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
882884004288	cation binding site [ion binding]; other site
882884004289	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
882884004290	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
882884004291	type III secretion system protein SsaT; Provisional; Region: PRK15349
882884004292	type III secretion system protein SsaS; Provisional; Region: PRK15350
882884004293	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
882884004294	type III secretion system protein SsaQ; Validated; Region: PRK08035
882884004295	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
882884004296	type III secretion system protein SsaP; Provisional; Region: PRK15351
882884004297	type III secretion system protein SsaO; Provisional; Region: PRK15352
882884004298	type III secretion system ATPase SsaN; Validated; Region: PRK07594
882884004299	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
882884004300	Walker A motif; other site
882884004301	ATP binding site [chemical binding]; other site
882884004302	Walker B motif; other site
882884004303	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
882884004304	FHIPEP family; Region: FHIPEP; pfam00771
882884004305	type III secretion system protein SsaL; Provisional; Region: PRK15345
882884004306	HrpJ-like domain; Region: HrpJ; cl15454
882884004307	TyeA; Region: TyeA; cl07611
882884004308	type III secretion system protein SsaK; Provisional; Region: PRK15354
882884004309	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
882884004310	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
882884004311	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
882884004312	type III secretion system protein SsaI; Provisional; Region: PRK15355
882884004313	type III secretion system protein SsaH; Provisional; Region: PRK15356
882884004314	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
882884004315	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
882884004316	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
882884004317	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
882884004318	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
882884004319	binding surface
882884004320	TPR motif; other site
882884004321	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
882884004322	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
882884004323	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
882884004324	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
882884004325	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
882884004326	type III secretion system chaperone SseA; Provisional; Region: PRK15365
882884004327	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
882884004328	type III secretion system protein SsaD; Provisional; Region: PRK15367
882884004329	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
882884004330	outer membrane secretin SsaC; Provisional; Region: PRK15346
882884004331	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
882884004332	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
882884004333	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
882884004334	two component system sensor kinase SsrA; Provisional; Region: PRK15347
882884004335	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884004336	dimerization interface [polypeptide binding]; other site
882884004337	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884004338	dimer interface [polypeptide binding]; other site
882884004339	phosphorylation site [posttranslational modification]
882884004340	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884004341	ATP binding site [chemical binding]; other site
882884004342	Mg2+ binding site [ion binding]; other site
882884004343	G-X-G motif; other site
882884004344	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884004345	active site
882884004346	phosphorylation site [posttranslational modification]
882884004347	intermolecular recognition site; other site
882884004348	dimerization interface [polypeptide binding]; other site
882884004349	two component system sensor kinase SsrB; Provisional; Region: PRK15369
882884004350	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884004351	active site
882884004352	phosphorylation site [posttranslational modification]
882884004353	intermolecular recognition site; other site
882884004354	dimerization interface [polypeptide binding]; other site
882884004355	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884004356	DNA binding residues [nucleotide binding]
882884004357	dimerization interface [polypeptide binding]; other site
882884004358	transcriptional regulator MirA; Provisional; Region: PRK15043
882884004359	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
882884004360	DNA binding residues [nucleotide binding]
882884004361	Uncharacterized conserved protein [Function unknown]; Region: COG1683
882884004362	Uncharacterized conserved protein [Function unknown]; Region: COG3272
882884004363	Protein of unknown function (DUF1722); Region: DUF1722; pfam08349
882884004364	hypothetical protein; Provisional; Region: PRK10292
882884004365	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
882884004366	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884004367	active site
882884004368	phosphorylation site [posttranslational modification]
882884004369	intermolecular recognition site; other site
882884004370	dimerization interface [polypeptide binding]; other site
882884004371	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884004372	DNA binding residues [nucleotide binding]
882884004373	dimerization interface [polypeptide binding]; other site
882884004374	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
882884004375	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
882884004376	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
882884004377	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884004378	dimer interface [polypeptide binding]; other site
882884004379	phosphorylation site [posttranslational modification]
882884004380	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884004381	ATP binding site [chemical binding]; other site
882884004382	Mg2+ binding site [ion binding]; other site
882884004383	G-X-G motif; other site
882884004384	tetrathionate reductase subunit B; Provisional; Region: PRK14993
882884004385	4Fe-4S binding domain; Region: Fer4; pfam00037
882884004386	tetrathionate reductase subunit C; Provisional; Region: PRK14992
882884004387	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
882884004388	tetrathionate reductase subunit A; Provisional; Region: PRK14991
882884004389	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
882884004390	putative [Fe4-S4] binding site [ion binding]; other site
882884004391	putative molybdopterin cofactor binding site [chemical binding]; other site
882884004392	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
882884004393	putative molybdopterin cofactor binding site; other site
882884004394	pyruvate kinase; Provisional; Region: PRK09206
882884004395	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
882884004396	domain interfaces; other site
882884004397	active site
882884004398	murein lipoprotein; Provisional; Region: PRK15396
882884004399	L,D-transpeptidase; Provisional; Region: PRK10190
882884004400	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
882884004401	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
882884004402	cysteine desufuration protein SufE; Provisional; Region: PRK09296
882884004403	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
882884004404	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
882884004405	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
882884004406	catalytic residue [active]
882884004407	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
882884004408	FeS assembly protein SufD; Region: sufD; TIGR01981
882884004409	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
882884004410	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
882884004411	Walker A/P-loop; other site
882884004412	ATP binding site [chemical binding]; other site
882884004413	Q-loop/lid; other site
882884004414	ABC transporter signature motif; other site
882884004415	Walker B; other site
882884004416	D-loop; other site
882884004417	H-loop/switch region; other site
882884004418	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
882884004419	putative ABC transporter; Region: ycf24; CHL00085
882884004420	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
882884004421	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
882884004422	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
882884004423	CoenzymeA binding site [chemical binding]; other site
882884004424	subunit interaction site [polypeptide binding]; other site
882884004425	PHB binding site; other site
882884004426	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
882884004427	FAD binding domain; Region: FAD_binding_4; pfam01565
882884004428	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
882884004429	putative inner membrane protein; Provisional; Region: PRK10983
882884004430	Domain of unknown function DUF20; Region: UPF0118; pfam01594
882884004431	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
882884004432	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
882884004433	active site
882884004434	catalytic residue [active]
882884004435	dimer interface [polypeptide binding]; other site
882884004436	phosphoenolpyruvate synthase; Validated; Region: PRK06464
882884004437	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
882884004438	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
882884004439	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
882884004440	PEP synthetase regulatory protein; Provisional; Region: PRK05339
882884004441	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
882884004442	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
882884004443	hypothetical protein; Provisional; Region: PRK10183
882884004444	Uncharacterized conserved protein [Function unknown]; Region: COG0397
882884004445	hypothetical protein; Validated; Region: PRK00029
882884004446	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
882884004447	NlpC/P60 family; Region: NLPC_P60; pfam00877
882884004448	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
882884004449	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
882884004450	Walker A/P-loop; other site
882884004451	ATP binding site [chemical binding]; other site
882884004452	Q-loop/lid; other site
882884004453	ABC transporter signature motif; other site
882884004454	Walker B; other site
882884004455	D-loop; other site
882884004456	H-loop/switch region; other site
882884004457	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
882884004458	catalytic residues [active]
882884004459	dimer interface [polypeptide binding]; other site
882884004460	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
882884004461	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
882884004462	ABC-ATPase subunit  interface; other site
882884004463	dimer interface [polypeptide binding]; other site
882884004464	putative PBP binding regions; other site
882884004465	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
882884004466	IHF dimer interface [polypeptide binding]; other site
882884004467	IHF - DNA interface [nucleotide binding]; other site
882884004468	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
882884004469	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
882884004470	putative tRNA-binding site [nucleotide binding]; other site
882884004471	B3/4 domain; Region: B3_4; pfam03483
882884004472	tRNA synthetase B5 domain; Region: B5; smart00874
882884004473	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
882884004474	dimer interface [polypeptide binding]; other site
882884004475	motif 1; other site
882884004476	motif 3; other site
882884004477	motif 2; other site
882884004478	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
882884004479	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
882884004480	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
882884004481	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
882884004482	dimer interface [polypeptide binding]; other site
882884004483	motif 1; other site
882884004484	active site
882884004485	motif 2; other site
882884004486	motif 3; other site
882884004487	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
882884004488	23S rRNA binding site [nucleotide binding]; other site
882884004489	L21 binding site [polypeptide binding]; other site
882884004490	L13 binding site [polypeptide binding]; other site
882884004491	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
882884004492	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
882884004493	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
882884004494	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
882884004495	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
882884004496	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
882884004497	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
882884004498	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
882884004499	active site
882884004500	dimer interface [polypeptide binding]; other site
882884004501	motif 1; other site
882884004502	motif 2; other site
882884004503	motif 3; other site
882884004504	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
882884004505	anticodon binding site; other site
882884004506	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
882884004507	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
882884004508	active site
882884004509	DNA binding site [nucleotide binding]
882884004510	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
882884004511	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
882884004512	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
882884004513	Catalytic site [active]
882884004514	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
882884004515	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
882884004516	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
882884004517	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
882884004518	Integrase core domain; Region: rve; pfam00665
882884004519	Winged helix-turn helix; Region: HTH_29; pfam13551
882884004520	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
882884004521	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
882884004522	active site
882884004523	substrate binding site [chemical binding]; other site
882884004524	Mg2+ binding site [ion binding]; other site
882884004525	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
882884004526	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
882884004527	6-phosphofructokinase 2; Provisional; Region: PRK10294
882884004528	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
882884004529	putative substrate binding site [chemical binding]; other site
882884004530	putative ATP binding site [chemical binding]; other site
882884004531	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
882884004532	Phosphotransferase enzyme family; Region: APH; pfam01636
882884004533	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
882884004534	active site
882884004535	ATP binding site [chemical binding]; other site
882884004536	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
882884004537	YniB-like protein; Region: YniB; pfam14002
882884004538	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
882884004539	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884004540	motif II; other site
882884004541	inner membrane protein; Provisional; Region: PRK11648
882884004542	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
882884004543	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
882884004544	cell division modulator; Provisional; Region: PRK10113
882884004545	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
882884004546	putative active site [active]
882884004547	YdjC motif; other site
882884004548	Mg binding site [ion binding]; other site
882884004549	putative homodimer interface [polypeptide binding]; other site
882884004550	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
882884004551	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
882884004552	NAD binding site [chemical binding]; other site
882884004553	sugar binding site [chemical binding]; other site
882884004554	divalent metal binding site [ion binding]; other site
882884004555	tetramer (dimer of dimers) interface [polypeptide binding]; other site
882884004556	dimer interface [polypeptide binding]; other site
882884004557	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
882884004558	Cupin domain; Region: Cupin_2; pfam07883
882884004559	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884004560	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
882884004561	methionine cluster; other site
882884004562	active site
882884004563	phosphorylation site [posttranslational modification]
882884004564	metal binding site [ion binding]; metal-binding site
882884004565	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
882884004566	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
882884004567	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
882884004568	active site
882884004569	P-loop; other site
882884004570	phosphorylation site [posttranslational modification]
882884004571	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
882884004572	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
882884004573	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
882884004574	homodimer interface [polypeptide binding]; other site
882884004575	NAD binding pocket [chemical binding]; other site
882884004576	ATP binding pocket [chemical binding]; other site
882884004577	Mg binding site [ion binding]; other site
882884004578	active-site loop [active]
882884004579	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
882884004580	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
882884004581	GIY-YIG motif/motif A; other site
882884004582	active site
882884004583	catalytic site [active]
882884004584	putative DNA binding site [nucleotide binding]; other site
882884004585	metal binding site [ion binding]; metal-binding site
882884004586	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
882884004587	dimer interface [polypeptide binding]; other site
882884004588	succinylglutamate desuccinylase; Provisional; Region: PRK05324
882884004589	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
882884004590	active site
882884004591	Zn binding site [ion binding]; other site
882884004592	succinylarginine dihydrolase; Provisional; Region: PRK13281
882884004593	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
882884004594	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
882884004595	NAD(P) binding site [chemical binding]; other site
882884004596	catalytic residues [active]
882884004597	arginine succinyltransferase; Provisional; Region: PRK10456
882884004598	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
882884004599	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
882884004600	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
882884004601	inhibitor-cofactor binding pocket; inhibition site
882884004602	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884004603	catalytic residue [active]
882884004604	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
882884004605	putative catalytic site [active]
882884004606	putative phosphate binding site [ion binding]; other site
882884004607	active site
882884004608	metal binding site A [ion binding]; metal-binding site
882884004609	DNA binding site [nucleotide binding]
882884004610	putative AP binding site [nucleotide binding]; other site
882884004611	putative metal binding site B [ion binding]; other site
882884004612	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
882884004613	active site
882884004614	8-oxo-dGMP binding site [chemical binding]; other site
882884004615	nudix motif; other site
882884004616	metal binding site [ion binding]; metal-binding site
882884004617	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
882884004618	glutamate dehydrogenase; Provisional; Region: PRK09414
882884004619	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
882884004620	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
882884004621	NAD(P) binding site [chemical binding]; other site
882884004622	DNA topoisomerase III; Provisional; Region: PRK07726
882884004623	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
882884004624	active site
882884004625	putative interdomain interaction site [polypeptide binding]; other site
882884004626	putative metal-binding site [ion binding]; other site
882884004627	putative nucleotide binding site [chemical binding]; other site
882884004628	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
882884004629	domain I; other site
882884004630	DNA binding groove [nucleotide binding]
882884004631	phosphate binding site [ion binding]; other site
882884004632	domain II; other site
882884004633	domain III; other site
882884004634	nucleotide binding site [chemical binding]; other site
882884004635	catalytic site [active]
882884004636	domain IV; other site
882884004637	selenophosphate synthetase; Provisional; Region: PRK00943
882884004638	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
882884004639	dimerization interface [polypeptide binding]; other site
882884004640	putative ATP binding site [chemical binding]; other site
882884004641	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
882884004642	putative FMN binding site [chemical binding]; other site
882884004643	protease 4; Provisional; Region: PRK10949
882884004644	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
882884004645	tandem repeat interface [polypeptide binding]; other site
882884004646	oligomer interface [polypeptide binding]; other site
882884004647	active site residues [active]
882884004648	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
882884004649	tandem repeat interface [polypeptide binding]; other site
882884004650	oligomer interface [polypeptide binding]; other site
882884004651	active site residues [active]
882884004652	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
882884004653	active site
882884004654	homodimer interface [polypeptide binding]; other site
882884004655	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
882884004656	Isochorismatase family; Region: Isochorismatase; pfam00857
882884004657	catalytic triad [active]
882884004658	metal binding site [ion binding]; metal-binding site
882884004659	conserved cis-peptide bond; other site
882884004660	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
882884004661	methionine sulfoxide reductase B; Provisional; Region: PRK00222
882884004662	SelR domain; Region: SelR; pfam01641
882884004663	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
882884004664	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
882884004665	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
882884004666	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
882884004667	active site
882884004668	phosphate binding residues; other site
882884004669	catalytic residues [active]
882884004670	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
882884004671	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
882884004672	active site
882884004673	catalytic tetrad [active]
882884004674	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
882884004675	PrkA family serine protein kinase; Provisional; Region: PRK15455
882884004676	AAA ATPase domain; Region: AAA_16; pfam13191
882884004677	Walker A motif; other site
882884004678	ATP binding site [chemical binding]; other site
882884004679	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
882884004680	hypothetical protein; Provisional; Region: PRK05325
882884004681	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
882884004682	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
882884004683	metal binding site [ion binding]; metal-binding site
882884004684	active site
882884004685	I-site; other site
882884004686	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
882884004687	putative deacylase active site [active]
882884004688	Predicted membrane protein [Function unknown]; Region: COG2707
882884004689	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
882884004690	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
882884004691	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884004692	putative substrate translocation pore; other site
882884004693	Uncharacterized conserved protein [Function unknown]; Region: COG3189
882884004694	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
882884004695	Domain of unknown function (DUF333); Region: DUF333; pfam03891
882884004696	hypothetical protein; Provisional; Region: PRK10457
882884004697	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
882884004698	leucine export protein LeuE; Provisional; Region: PRK10958
882884004699	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
882884004700	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884004701	substrate binding pocket [chemical binding]; other site
882884004702	membrane-bound complex binding site; other site
882884004703	hinge residues; other site
882884004704	chorismate mutase; Provisional; Region: PRK08055
882884004705	Pleckstrin homology-like domain; Region: PH-like; cl17171
882884004706	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
882884004707	transcriptional regulator MirA; Provisional; Region: PRK15043
882884004708	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
882884004709	DNA binding residues [nucleotide binding]
882884004710	dimer interface [polypeptide binding]; other site
882884004711	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884004712	DNA binding residues [nucleotide binding]
882884004713	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
882884004714	zinc/cadmium-binding protein; Provisional; Region: PRK10306
882884004715	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
882884004716	dimerization interface [polypeptide binding]; other site
882884004717	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
882884004718	Mechanosensitive ion channel; Region: MS_channel; pfam00924
882884004719	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884004720	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
882884004721	Walker A/P-loop; other site
882884004722	ATP binding site [chemical binding]; other site
882884004723	Q-loop/lid; other site
882884004724	ABC transporter signature motif; other site
882884004725	Walker B; other site
882884004726	D-loop; other site
882884004727	H-loop/switch region; other site
882884004728	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884004729	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
882884004730	Walker A/P-loop; other site
882884004731	ATP binding site [chemical binding]; other site
882884004732	Q-loop/lid; other site
882884004733	ABC transporter signature motif; other site
882884004734	Walker B; other site
882884004735	D-loop; other site
882884004736	H-loop/switch region; other site
882884004737	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
882884004738	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884004739	dimer interface [polypeptide binding]; other site
882884004740	conserved gate region; other site
882884004741	putative PBP binding loops; other site
882884004742	ABC-ATPase subunit interface; other site
882884004743	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
882884004744	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884004745	dimer interface [polypeptide binding]; other site
882884004746	conserved gate region; other site
882884004747	ABC-ATPase subunit interface; other site
882884004748	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
882884004749	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
882884004750	TRL-like protein family; Region: TRL; pfam13146
882884004751	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
882884004752	BNR repeat-like domain; Region: BNR_2; pfam13088
882884004753	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
882884004754	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
882884004755	putative dimer interface [polypeptide binding]; other site
882884004756	lysozyme inhibitor; Provisional; Region: PRK13791
882884004757	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
882884004758	Ricin-type beta-trefoil; Region: RICIN; smart00458
882884004759	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
882884004760	putative sugar binding sites [chemical binding]; other site
882884004761	Q-X-W motif; other site
882884004762	DinI-like family; Region: DinI; pfam06183
882884004763	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
882884004764	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
882884004765	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
882884004766	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
882884004767	Autotransporter beta-domain; Region: Autotransporter; pfam03797
882884004768	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
882884004769	Bor protein; Region: Lambda_Bor; pfam06291
882884004770	outer membrane protease; Reviewed; Region: PRK10993
882884004771	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317
882884004772	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
882884004773	dimer interface [polypeptide binding]; other site
882884004774	catalytic triad [active]
882884004775	Integrase core domain; Region: rve; pfam00665
882884004776	Integrase core domain; Region: rve_2; pfam13333
882884004777	PipA protein; Region: PipA; pfam07108
882884004778	isocitrate dehydrogenase; Validated; Region: PRK07362
882884004779	isocitrate dehydrogenase; Reviewed; Region: PRK07006
882884004780	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
882884004781	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
882884004782	probable active site [active]
882884004783	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
882884004784	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
882884004785	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
882884004786	nudix motif; other site
882884004787	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
882884004788	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
882884004789	putative lysogenization regulator; Reviewed; Region: PRK00218
882884004790	adenylosuccinate lyase; Provisional; Region: PRK09285
882884004791	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
882884004792	tetramer interface [polypeptide binding]; other site
882884004793	active site
882884004794	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
882884004795	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884004796	active site
882884004797	phosphorylation site [posttranslational modification]
882884004798	intermolecular recognition site; other site
882884004799	dimerization interface [polypeptide binding]; other site
882884004800	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884004801	DNA binding site [nucleotide binding]
882884004802	sensor protein PhoQ; Provisional; Region: PRK10815
882884004803	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
882884004804	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
882884004805	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884004806	ATP binding site [chemical binding]; other site
882884004807	Mg2+ binding site [ion binding]; other site
882884004808	G-X-G motif; other site
882884004809	Uncharacterized conserved protein [Function unknown]; Region: COG2850
882884004810	Cupin domain; Region: Cupin_2; cl17218
882884004811	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
882884004812	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
882884004813	metal binding site [ion binding]; metal-binding site
882884004814	dimer interface [polypeptide binding]; other site
882884004815	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
882884004816	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884004817	Walker A/P-loop; other site
882884004818	ATP binding site [chemical binding]; other site
882884004819	Q-loop/lid; other site
882884004820	ABC transporter signature motif; other site
882884004821	Walker B; other site
882884004822	D-loop; other site
882884004823	H-loop/switch region; other site
882884004824	TOBE domain; Region: TOBE_2; pfam08402
882884004825	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
882884004826	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884004827	dimer interface [polypeptide binding]; other site
882884004828	conserved gate region; other site
882884004829	putative PBP binding loops; other site
882884004830	ABC-ATPase subunit interface; other site
882884004831	Sif protein; Region: Sif; pfam06767
882884004832	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
882884004833	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884004834	dimer interface [polypeptide binding]; other site
882884004835	conserved gate region; other site
882884004836	putative PBP binding loops; other site
882884004837	ABC-ATPase subunit interface; other site
882884004838	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
882884004839	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
882884004840	NAD-dependent deacetylase; Provisional; Region: PRK00481
882884004841	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
882884004842	NAD+ binding site [chemical binding]; other site
882884004843	substrate binding site [chemical binding]; other site
882884004844	Zn binding site [ion binding]; other site
882884004845	fructokinase; Reviewed; Region: PRK09557
882884004846	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
882884004847	nucleotide binding site [chemical binding]; other site
882884004848	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
882884004849	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
882884004850	FtsX-like permease family; Region: FtsX; pfam02687
882884004851	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
882884004852	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
882884004853	Walker A/P-loop; other site
882884004854	ATP binding site [chemical binding]; other site
882884004855	Q-loop/lid; other site
882884004856	ABC transporter signature motif; other site
882884004857	Walker B; other site
882884004858	D-loop; other site
882884004859	H-loop/switch region; other site
882884004860	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
882884004861	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
882884004862	FtsX-like permease family; Region: FtsX; pfam02687
882884004863	transcription-repair coupling factor; Provisional; Region: PRK10689
882884004864	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
882884004865	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884004866	ATP binding site [chemical binding]; other site
882884004867	putative Mg++ binding site [ion binding]; other site
882884004868	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884004869	nucleotide binding region [chemical binding]; other site
882884004870	ATP-binding site [chemical binding]; other site
882884004871	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
882884004872	L,D-transpeptidase; Provisional; Region: PRK10190
882884004873	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
882884004874	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
882884004875	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884004876	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
882884004877	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884004878	RecT family; Region: RecT; cl04285
882884004879	hypothetical protein; Provisional; Region: PRK11280
882884004880	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
882884004881	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884004882	hypothetical protein; Provisional; Region: PRK04940
882884004883	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
882884004884	beta-hexosaminidase; Provisional; Region: PRK05337
882884004885	thiamine kinase; Region: ycfN_thiK; TIGR02721
882884004886	thiamine kinase; Provisional; Region: thiK; PRK10271
882884004887	substrate binding site [chemical binding]; other site
882884004888	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
882884004889	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
882884004890	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
882884004891	putative dimer interface [polypeptide binding]; other site
882884004892	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
882884004893	nucleotide binding site/active site [active]
882884004894	HIT family signature motif; other site
882884004895	catalytic residue [active]
882884004896	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
882884004897	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
882884004898	N-terminal plug; other site
882884004899	ligand-binding site [chemical binding]; other site
882884004900	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
882884004901	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
882884004902	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
882884004903	active site turn [active]
882884004904	phosphorylation site [posttranslational modification]
882884004905	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
882884004906	active site
882884004907	DNA polymerase III subunit delta'; Validated; Region: PRK07993
882884004908	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
882884004909	thymidylate kinase; Validated; Region: tmk; PRK00698
882884004910	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
882884004911	TMP-binding site; other site
882884004912	ATP-binding site [chemical binding]; other site
882884004913	conserved hypothetical protein, YceG family; Region: TIGR00247
882884004914	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
882884004915	dimerization interface [polypeptide binding]; other site
882884004916	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
882884004917	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
882884004918	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884004919	catalytic residue [active]
882884004920	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
882884004921	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
882884004922	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
882884004923	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
882884004924	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
882884004925	PapC N-terminal domain; Region: PapC_N; pfam13954
882884004926	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
882884004927	PapC C-terminal domain; Region: PapC_C; pfam13953
882884004928	Fimbrial protein; Region: Fimbrial; pfam00419
882884004929	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
882884004930	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
882884004931	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
882884004932	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
882884004933	dimer interface [polypeptide binding]; other site
882884004934	active site
882884004935	acyl carrier protein; Provisional; Region: acpP; PRK00982
882884004936	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
882884004937	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
882884004938	NAD(P) binding site [chemical binding]; other site
882884004939	homotetramer interface [polypeptide binding]; other site
882884004940	homodimer interface [polypeptide binding]; other site
882884004941	active site
882884004942	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
882884004943	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
882884004944	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
882884004945	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
882884004946	dimer interface [polypeptide binding]; other site
882884004947	active site
882884004948	CoA binding pocket [chemical binding]; other site
882884004949	putative phosphate acyltransferase; Provisional; Region: PRK05331
882884004950	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
882884004951	hypothetical protein; Provisional; Region: PRK11193
882884004952	Maf-like protein; Region: Maf; pfam02545
882884004953	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
882884004954	active site
882884004955	dimer interface [polypeptide binding]; other site
882884004956	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
882884004957	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
882884004958	RNA binding surface [nucleotide binding]; other site
882884004959	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
882884004960	active site
882884004961	RNAse e 5' utr element
882884004962	ribonuclease E; Reviewed; Region: rne; PRK10811
882884004963	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
882884004964	homodimer interface [polypeptide binding]; other site
882884004965	oligonucleotide binding site [chemical binding]; other site
882884004966	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
882884004967	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
882884004968	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
882884004969	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
882884004970	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
882884004971	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
882884004972	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
882884004973	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
882884004974	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
882884004975	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
882884004976	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
882884004977	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
882884004978	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
882884004979	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
882884004980	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
882884004981	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
882884004982	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
882884004983	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
882884004984	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
882884004985	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
882884004986	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
882884004987	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
882884004988	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
882884004989	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
882884004990	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
882884004991	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
882884004992	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
882884004993	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
882884004994	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
882884004995	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
882884004996	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
882884004997	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
882884004998	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
882884004999	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
882884005000	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
882884005001	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
882884005002	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
882884005003	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
882884005004	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
882884005005	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
882884005006	hypothetical protein; Provisional; Region: PRK11239
882884005007	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
882884005008	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
882884005009	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
882884005010	multidrug resistance protein MdtH; Provisional; Region: PRK11646
882884005011	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884005012	putative substrate translocation pore; other site
882884005013	glutaredoxin 2; Provisional; Region: PRK10387
882884005014	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
882884005015	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
882884005016	N-terminal domain interface [polypeptide binding]; other site
882884005017	lipoprotein; Provisional; Region: PRK10598
882884005018	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
882884005019	active site
882884005020	substrate binding pocket [chemical binding]; other site
882884005021	dimer interface [polypeptide binding]; other site
882884005022	DNA damage-inducible protein I; Provisional; Region: PRK10597
882884005023	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
882884005024	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
882884005025	hydroxyglutarate oxidase; Provisional; Region: PRK11728
882884005026	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
882884005027	hypothetical protein; Provisional; Region: PRK03757
882884005028	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
882884005029	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
882884005030	active site residue [active]
882884005031	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
882884005032	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
882884005033	putative acyl-acceptor binding pocket; other site
882884005034	drug efflux system protein MdtG; Provisional; Region: PRK09874
882884005035	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884005036	putative substrate translocation pore; other site
882884005037	secY/secA suppressor protein; Provisional; Region: PRK11467
882884005038	lipoprotein; Provisional; Region: PRK10175
882884005039	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
882884005040	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
882884005041	Ligand binding site; other site
882884005042	DXD motif; other site
882884005043	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
882884005044	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
882884005045	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
882884005046	Acyltransferase family; Region: Acyl_transf_3; pfam01757
882884005047	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
882884005048	PLD-like domain; Region: PLDc_2; pfam13091
882884005049	putative active site [active]
882884005050	catalytic site [active]
882884005051	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
882884005052	PLD-like domain; Region: PLDc_2; pfam13091
882884005053	putative active site [active]
882884005054	catalytic site [active]
882884005055	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
882884005056	putative ADP-ribose binding site [chemical binding]; other site
882884005057	putative active site [active]
882884005058	Fimbrial protein; Region: Fimbrial; cl01416
882884005059	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
882884005060	major curlin subunit; Provisional; Region: csgA; PRK10051
882884005061	Curlin associated repeat; Region: Curlin_rpt; pfam07012
882884005062	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
882884005063	Curlin associated repeat; Region: Curlin_rpt; pfam07012
882884005064	Curlin associated repeat; Region: Curlin_rpt; pfam07012
882884005065	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
882884005066	Type VIII secretion system (T8SS), CsgF protein; Region: CsgF; cl08082
882884005067	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
882884005068	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
882884005069	putative hydrolase; Validated; Region: PRK09248
882884005070	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
882884005071	active site
882884005072	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
882884005073	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
882884005074	putative ligand binding site [chemical binding]; other site
882884005075	NAD binding site [chemical binding]; other site
882884005076	dimerization interface [polypeptide binding]; other site
882884005077	catalytic site [active]
882884005078	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
882884005079	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
882884005080	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
882884005081	putative sialic acid transporter; Provisional; Region: PRK12307
882884005082	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884005083	putative substrate translocation pore; other site
882884005084	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
882884005085	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
882884005086	Kelch motif; Region: Kelch_1; pfam01344
882884005087	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
882884005088	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
882884005089	putative active site cavity [active]
882884005090	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
882884005091	Na binding site [ion binding]; other site
882884005092	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
882884005093	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
882884005094	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
882884005095	putative active site [active]
882884005096	hypothetical protein; Provisional; Region: PRK10536
882884005097	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
882884005098	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
882884005099	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
882884005100	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
882884005101	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
882884005102	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
882884005103	Na binding site [ion binding]; other site
882884005104	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
882884005105	Predicted transcriptional regulator [Transcription]; Region: COG3905
882884005106	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
882884005107	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
882884005108	Glutamate binding site [chemical binding]; other site
882884005109	NAD binding site [chemical binding]; other site
882884005110	catalytic residues [active]
882884005111	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
882884005112	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
882884005113	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884005114	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
882884005115	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
882884005116	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
882884005117	hypothetical protein; Provisional; Region: PRK10174
882884005118	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
882884005119	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
882884005120	catalytic core [active]
882884005121	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
882884005122	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
882884005123	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
882884005124	catalytic residues [active]
882884005125	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
882884005126	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
882884005127	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
882884005128	catalytic residues [active]
882884005129	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
882884005130	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
882884005131	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
882884005132	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
882884005133	DsbD alpha interface [polypeptide binding]; other site
882884005134	catalytic residues [active]
882884005135	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
882884005136	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
882884005137	HSP70 interaction site [polypeptide binding]; other site
882884005138	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
882884005139	substrate binding site [polypeptide binding]; other site
882884005140	dimer interface [polypeptide binding]; other site
882884005141	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
882884005142	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
882884005143	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
882884005144	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
882884005145	Cupin domain; Region: Cupin_2; pfam07883
882884005146	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884005147	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884005148	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
882884005149	putative substrate translocation pore; other site
882884005150	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
882884005151	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
882884005152	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
882884005153	putative substrate binding pocket [chemical binding]; other site
882884005154	trimer interface [polypeptide binding]; other site
882884005155	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
882884005156	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
882884005157	putative active site [active]
882884005158	putative metal binding site [ion binding]; other site
882884005159	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
882884005160	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
882884005161	NAD binding site [chemical binding]; other site
882884005162	catalytic residues [active]
882884005163	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
882884005164	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
882884005165	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
882884005166	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
882884005167	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
882884005168	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
882884005169	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
882884005170	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
882884005171	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
882884005172	active site
882884005173	homotetramer interface [polypeptide binding]; other site
882884005174	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
882884005175	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884005176	active site
882884005177	phosphorylation site [posttranslational modification]
882884005178	intermolecular recognition site; other site
882884005179	dimerization interface [polypeptide binding]; other site
882884005180	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884005181	DNA binding site [nucleotide binding]
882884005182	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
882884005183	HAMP domain; Region: HAMP; pfam00672
882884005184	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884005185	dimer interface [polypeptide binding]; other site
882884005186	phosphorylation site [posttranslational modification]
882884005187	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884005188	ATP binding site [chemical binding]; other site
882884005189	Mg2+ binding site [ion binding]; other site
882884005190	G-X-G motif; other site
882884005191	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
882884005192	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
882884005193	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
882884005194	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
882884005195	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
882884005196	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
882884005197	secreted effector protein PipB; Provisional; Region: PRK15197
882884005198	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
882884005199	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
882884005200	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
882884005201	catalytic residues [active]
882884005202	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
882884005203	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
882884005204	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
882884005205	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
882884005206	YccA-like proteins; Region: YccA_like; cd10433
882884005207	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
882884005208	sulfur transfer protein TusE; Provisional; Region: PRK11508
882884005209	acylphosphatase; Provisional; Region: PRK14426
882884005210	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
882884005211	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
882884005212	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
882884005213	putative RNA binding site [nucleotide binding]; other site
882884005214	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884005215	S-adenosylmethionine binding site [chemical binding]; other site
882884005216	heat shock protein HspQ; Provisional; Region: PRK14129
882884005217	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
882884005218	hypothetical protein; Provisional; Region: PRK03641
882884005219	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
882884005220	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
882884005221	active site
882884005222	dimer interfaces [polypeptide binding]; other site
882884005223	catalytic residues [active]
882884005224	DNA helicase IV; Provisional; Region: helD; PRK11054
882884005225	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
882884005226	Part of AAA domain; Region: AAA_19; pfam13245
882884005227	Family description; Region: UvrD_C_2; pfam13538
882884005228	Predicted membrane protein [Function unknown]; Region: COG3304
882884005229	Domain of unknown function (DUF307); Region: DUF307; pfam03733
882884005230	Domain of unknown function (DUF307); Region: DUF307; pfam03733
882884005231	TIGR01666 family membrane protein; Region: YCCS
882884005232	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
882884005233	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
882884005234	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
882884005235	TfoX C-terminal domain; Region: TfoX_C; pfam04994
882884005236	cell division inhibitor SulA; Region: sula; TIGR00623
882884005237	outer membrane protein A; Reviewed; Region: PRK10808
882884005238	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
882884005239	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
882884005240	ligand binding site [chemical binding]; other site
882884005241	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
882884005242	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
882884005243	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
882884005244	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
882884005245	active site 1 [active]
882884005246	dimer interface [polypeptide binding]; other site
882884005247	active site 2 [active]
882884005248	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
882884005249	Protein of unknown function (DUF330); Region: DUF330; pfam03886
882884005250	paraquat-inducible protein B; Provisional; Region: PRK10807
882884005251	mce related protein; Region: MCE; pfam02470
882884005252	mce related protein; Region: MCE; pfam02470
882884005253	mce related protein; Region: MCE; pfam02470
882884005254	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
882884005255	Paraquat-inducible protein A; Region: PqiA; pfam04403
882884005256	Paraquat-inducible protein A; Region: PqiA; pfam04403
882884005257	ABC transporter ATPase component; Reviewed; Region: PRK11147
882884005258	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884005259	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884005260	Walker A/P-loop; other site
882884005261	Walker A/P-loop; other site
882884005262	ATP binding site [chemical binding]; other site
882884005263	ATP binding site [chemical binding]; other site
882884005264	Q-loop/lid; other site
882884005265	Q-loop/lid; other site
882884005266	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884005267	ABC transporter signature motif; other site
882884005268	Walker B; other site
882884005269	D-loop; other site
882884005270	ABC transporter; Region: ABC_tran_2; pfam12848
882884005271	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884005272	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
882884005273	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
882884005274	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
882884005275	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884005276	S-adenosylmethionine binding site [chemical binding]; other site
882884005277	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
882884005278	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
882884005279	MOSC domain; Region: MOSC; pfam03473
882884005280	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
882884005281	catalytic loop [active]
882884005282	iron binding site [ion binding]; other site
882884005283	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
882884005284	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
882884005285	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
882884005286	quinone interaction residues [chemical binding]; other site
882884005287	active site
882884005288	catalytic residues [active]
882884005289	FMN binding site [chemical binding]; other site
882884005290	substrate binding site [chemical binding]; other site
882884005291	aminopeptidase N; Provisional; Region: pepN; PRK14015
882884005292	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
882884005293	active site
882884005294	Zn binding site [ion binding]; other site
882884005295	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
882884005296	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
882884005297	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
882884005298	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
882884005299	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
882884005300	active site
882884005301	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
882884005302	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
882884005303	putative dimer interface [polypeptide binding]; other site
882884005304	putative anticodon binding site; other site
882884005305	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
882884005306	homodimer interface [polypeptide binding]; other site
882884005307	motif 1; other site
882884005308	motif 2; other site
882884005309	active site
882884005310	motif 3; other site
882884005311	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
882884005312	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
882884005313	trimer interface [polypeptide binding]; other site
882884005314	eyelet of channel; other site
882884005315	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
882884005316	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884005317	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884005318	homodimer interface [polypeptide binding]; other site
882884005319	catalytic residue [active]
882884005320	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
882884005321	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
882884005322	Peptidase M15; Region: Peptidase_M15_3; cl01194
882884005323	murein L,D-transpeptidase; Provisional; Region: PRK10594
882884005324	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
882884005325	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
882884005326	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
882884005327	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
882884005328	P-loop containing region of AAA domain; Region: AAA_29; cl17516
882884005329	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
882884005330	condesin subunit E; Provisional; Region: PRK05256
882884005331	condesin subunit F; Provisional; Region: PRK05260
882884005332	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
882884005333	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884005334	S-adenosylmethionine binding site [chemical binding]; other site
882884005335	Uncharacterized conserved protein [Function unknown]; Region: COG1434
882884005336	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
882884005337	putative active site [active]
882884005338	hypothetical protein; Provisional; Region: PRK10593
882884005339	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
882884005340	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
882884005341	Ligand binding site; other site
882884005342	oligomer interface; other site
882884005343	hypothetical protein; Provisional; Region: PRK11827
882884005344	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
882884005345	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
882884005346	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
882884005347	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
882884005348	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
882884005349	Walker A/P-loop; other site
882884005350	ATP binding site [chemical binding]; other site
882884005351	Q-loop/lid; other site
882884005352	ABC transporter signature motif; other site
882884005353	Walker B; other site
882884005354	D-loop; other site
882884005355	H-loop/switch region; other site
882884005356	ComEC family competence protein; Provisional; Region: PRK11539
882884005357	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
882884005358	Competence protein; Region: Competence; pfam03772
882884005359	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
882884005360	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
882884005361	IHF dimer interface [polypeptide binding]; other site
882884005362	IHF - DNA interface [nucleotide binding]; other site
882884005363	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
882884005364	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
882884005365	RNA binding site [nucleotide binding]; other site
882884005366	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
882884005367	RNA binding site [nucleotide binding]; other site
882884005368	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
882884005369	RNA binding site [nucleotide binding]; other site
882884005370	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
882884005371	RNA binding site [nucleotide binding]; other site
882884005372	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
882884005373	RNA binding site [nucleotide binding]; other site
882884005374	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
882884005375	RNA binding site [nucleotide binding]; other site
882884005376	cytidylate kinase; Provisional; Region: cmk; PRK00023
882884005377	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
882884005378	CMP-binding site; other site
882884005379	The sites determining sugar specificity; other site
882884005380	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
882884005381	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
882884005382	putative active site [active]
882884005383	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
882884005384	homodimer interface [polypeptide binding]; other site
882884005385	substrate-cofactor binding pocket; other site
882884005386	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884005387	catalytic residue [active]
882884005388	Predicted membrane protein [Function unknown]; Region: COG2323
882884005389	uncharacterized domain; Region: TIGR00702
882884005390	YcaO-like family; Region: YcaO; pfam02624
882884005391	formate transporter; Provisional; Region: PRK10805
882884005392	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
882884005393	Pyruvate formate lyase 1; Region: PFL1; cd01678
882884005394	coenzyme A binding site [chemical binding]; other site
882884005395	active site
882884005396	catalytic residues [active]
882884005397	glycine loop; other site
882884005398	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
882884005399	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
882884005400	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884005401	FeS/SAM binding site; other site
882884005402	inner membrane transporter YjeM; Provisional; Region: PRK15238
882884005403	putative MFS family transporter protein; Provisional; Region: PRK03633
882884005404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884005405	putative substrate translocation pore; other site
882884005406	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
882884005407	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
882884005408	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
882884005409	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
882884005410	4Fe-4S binding domain; Region: Fer4; pfam00037
882884005411	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
882884005412	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
882884005413	putative [Fe4-S4] binding site [ion binding]; other site
882884005414	putative molybdopterin cofactor binding site [chemical binding]; other site
882884005415	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
882884005416	putative molybdopterin cofactor binding site; other site
882884005417	seryl-tRNA synthetase; Provisional; Region: PRK05431
882884005418	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
882884005419	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
882884005420	dimer interface [polypeptide binding]; other site
882884005421	active site
882884005422	motif 1; other site
882884005423	motif 2; other site
882884005424	motif 3; other site
882884005425	recombination factor protein RarA; Reviewed; Region: PRK13342
882884005426	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884005427	Walker A motif; other site
882884005428	ATP binding site [chemical binding]; other site
882884005429	Walker B motif; other site
882884005430	arginine finger; other site
882884005431	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
882884005432	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
882884005433	periplasmic chaperone LolA; Region: lolA; TIGR00547
882884005434	DNA translocase FtsK; Provisional; Region: PRK10263
882884005435	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
882884005436	DNA translocase FtsK; Provisional; Region: PRK10263
882884005437	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
882884005438	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
882884005439	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
882884005440	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
882884005441	putative DNA binding site [nucleotide binding]; other site
882884005442	putative Zn2+ binding site [ion binding]; other site
882884005443	AsnC family; Region: AsnC_trans_reg; pfam01037
882884005444	thioredoxin reductase; Provisional; Region: PRK10262
882884005445	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
882884005446	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884005447	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
882884005448	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
882884005449	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884005450	Walker A/P-loop; other site
882884005451	ATP binding site [chemical binding]; other site
882884005452	Q-loop/lid; other site
882884005453	ABC transporter signature motif; other site
882884005454	Walker B; other site
882884005455	D-loop; other site
882884005456	H-loop/switch region; other site
882884005457	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
882884005458	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
882884005459	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884005460	Walker A/P-loop; other site
882884005461	ATP binding site [chemical binding]; other site
882884005462	Q-loop/lid; other site
882884005463	ABC transporter signature motif; other site
882884005464	Walker B; other site
882884005465	D-loop; other site
882884005466	H-loop/switch region; other site
882884005467	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
882884005468	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
882884005469	rRNA binding site [nucleotide binding]; other site
882884005470	predicted 30S ribosome binding site; other site
882884005471	LysR family transcriptional regulator; Provisional; Region: PRK14997
882884005472	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884005473	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
882884005474	putative effector binding pocket; other site
882884005475	putative dimerization interface [polypeptide binding]; other site
882884005476	Pirin-related protein [General function prediction only]; Region: COG1741
882884005477	Pirin; Region: Pirin; pfam02678
882884005478	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
882884005479	Isochorismatase family; Region: Isochorismatase; pfam00857
882884005480	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
882884005481	catalytic triad [active]
882884005482	dimer interface [polypeptide binding]; other site
882884005483	conserved cis-peptide bond; other site
882884005484	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
882884005485	Clp amino terminal domain; Region: Clp_N; pfam02861
882884005486	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884005487	Walker A motif; other site
882884005488	ATP binding site [chemical binding]; other site
882884005489	Walker B motif; other site
882884005490	arginine finger; other site
882884005491	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884005492	Walker A motif; other site
882884005493	ATP binding site [chemical binding]; other site
882884005494	Walker B motif; other site
882884005495	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
882884005496	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
882884005497	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
882884005498	DNA-binding site [nucleotide binding]; DNA binding site
882884005499	RNA-binding motif; other site
882884005500	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
882884005501	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
882884005502	Walker A/P-loop; other site
882884005503	ATP binding site [chemical binding]; other site
882884005504	Q-loop/lid; other site
882884005505	ABC transporter signature motif; other site
882884005506	Walker B; other site
882884005507	D-loop; other site
882884005508	H-loop/switch region; other site
882884005509	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
882884005510	FtsX-like permease family; Region: FtsX; pfam02687
882884005511	macrolide transporter subunit MacA; Provisional; Region: PRK11578
882884005512	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
882884005513	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884005514	Protein of unknown function (DUF535); Region: DUF535; pfam04393
882884005515	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
882884005516	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
882884005517	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
882884005518	putative active site [active]
882884005519	putative metal-binding site [ion binding]; other site
882884005520	Predicted membrane protein [Function unknown]; Region: COG2431
882884005521	hybrid cluster protein; Provisional; Region: PRK05290
882884005522	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
882884005523	ACS interaction site; other site
882884005524	CODH interaction site; other site
882884005525	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
882884005526	hybrid metal cluster; other site
882884005527	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
882884005528	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
882884005529	FAD binding pocket [chemical binding]; other site
882884005530	FAD binding motif [chemical binding]; other site
882884005531	phosphate binding motif [ion binding]; other site
882884005532	beta-alpha-beta structure motif; other site
882884005533	NAD binding pocket [chemical binding]; other site
882884005534	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
882884005535	catalytic loop [active]
882884005536	iron binding site [ion binding]; other site
882884005537	pyruvate dehydrogenase; Provisional; Region: PRK09124
882884005538	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
882884005539	PYR/PP interface [polypeptide binding]; other site
882884005540	dimer interface [polypeptide binding]; other site
882884005541	tetramer interface [polypeptide binding]; other site
882884005542	TPP binding site [chemical binding]; other site
882884005543	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
882884005544	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
882884005545	TPP-binding site [chemical binding]; other site
882884005546	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
882884005547	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
882884005548	tetramer interface [polypeptide binding]; other site
882884005549	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884005550	catalytic residue [active]
882884005551	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
882884005552	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
882884005553	putative NAD(P) binding site [chemical binding]; other site
882884005554	putative active site [active]
882884005555	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
882884005556	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
882884005557	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
882884005558	NAD(P) binding site [chemical binding]; other site
882884005559	active site
882884005560	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
882884005561	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
882884005562	amidase catalytic site [active]
882884005563	Zn binding residues [ion binding]; other site
882884005564	substrate binding site [chemical binding]; other site
882884005565	hypothetical protein; Provisional; Region: PRK02877
882884005566	Integrase core domain; Region: rve; pfam00665
882884005567	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884005568	Transposase; Region: HTH_Tnp_1; cl17663
882884005569	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884005570	DNA binding site [nucleotide binding]
882884005571	active site
882884005572	Int/Topo IB signature motif; other site
882884005573	putative lipoprotein; Provisional; Region: PRK10533
882884005574	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
882884005575	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884005576	Walker A/P-loop; other site
882884005577	ATP binding site [chemical binding]; other site
882884005578	Q-loop/lid; other site
882884005579	ABC transporter signature motif; other site
882884005580	Walker B; other site
882884005581	D-loop; other site
882884005582	H-loop/switch region; other site
882884005583	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
882884005584	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884005585	dimer interface [polypeptide binding]; other site
882884005586	conserved gate region; other site
882884005587	putative PBP binding loops; other site
882884005588	ABC-ATPase subunit interface; other site
882884005589	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884005590	dimer interface [polypeptide binding]; other site
882884005591	conserved gate region; other site
882884005592	putative PBP binding loops; other site
882884005593	ABC-ATPase subunit interface; other site
882884005594	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
882884005595	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884005596	substrate binding pocket [chemical binding]; other site
882884005597	membrane-bound complex binding site; other site
882884005598	hinge residues; other site
882884005599	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884005600	Sulfatase; Region: Sulfatase; cl17466
882884005601	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
882884005602	active site
882884005603	P-loop; other site
882884005604	phosphorylation site [posttranslational modification]
882884005605	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
882884005606	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
882884005607	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884005608	S-adenosylmethionine binding site [chemical binding]; other site
882884005609	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
882884005610	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
882884005611	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884005612	dimer interface [polypeptide binding]; other site
882884005613	conserved gate region; other site
882884005614	putative PBP binding loops; other site
882884005615	ABC-ATPase subunit interface; other site
882884005616	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884005617	dimer interface [polypeptide binding]; other site
882884005618	conserved gate region; other site
882884005619	putative PBP binding loops; other site
882884005620	ABC-ATPase subunit interface; other site
882884005621	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
882884005622	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
882884005623	Walker A/P-loop; other site
882884005624	ATP binding site [chemical binding]; other site
882884005625	Q-loop/lid; other site
882884005626	ABC transporter signature motif; other site
882884005627	Walker B; other site
882884005628	D-loop; other site
882884005629	H-loop/switch region; other site
882884005630	TOBE domain; Region: TOBE_2; pfam08402
882884005631	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
882884005632	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
882884005633	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
882884005634	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
882884005635	RimK-like ATP-grasp domain; Region: RimK; pfam08443
882884005636	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
882884005637	dimer interface [polypeptide binding]; other site
882884005638	FMN binding site [chemical binding]; other site
882884005639	NADPH bind site [chemical binding]; other site
882884005640	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
882884005641	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
882884005642	GSH binding site [chemical binding]; other site
882884005643	catalytic residues [active]
882884005644	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
882884005645	putative transporter; Provisional; Region: PRK04972
882884005646	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
882884005647	TrkA-C domain; Region: TrkA_C; pfam02080
882884005648	TrkA-C domain; Region: TrkA_C; pfam02080
882884005649	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
882884005650	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884005651	putative substrate translocation pore; other site
882884005652	Major Facilitator Superfamily; Region: MFS_1; pfam07690
882884005653	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
882884005654	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
882884005655	active site
882884005656	motif I; other site
882884005657	motif II; other site
882884005658	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884005659	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
882884005660	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884005661	putative substrate translocation pore; other site
882884005662	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
882884005663	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
882884005664	active site
882884005665	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
882884005666	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
882884005667	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884005668	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
882884005669	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
882884005670	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
882884005671	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
882884005672	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
882884005673	putative C-terminal domain interface [polypeptide binding]; other site
882884005674	putative GSH binding site (G-site) [chemical binding]; other site
882884005675	putative dimer interface [polypeptide binding]; other site
882884005676	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
882884005677	putative N-terminal domain interface [polypeptide binding]; other site
882884005678	putative dimer interface [polypeptide binding]; other site
882884005679	putative substrate binding pocket (H-site) [chemical binding]; other site
882884005680	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
882884005681	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
882884005682	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
882884005683	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
882884005684	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
882884005685	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884005686	FeS/SAM binding site; other site
882884005687	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
882884005688	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
882884005689	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884005690	dimer interface [polypeptide binding]; other site
882884005691	conserved gate region; other site
882884005692	putative PBP binding loops; other site
882884005693	ABC-ATPase subunit interface; other site
882884005694	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
882884005695	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884005696	dimer interface [polypeptide binding]; other site
882884005697	conserved gate region; other site
882884005698	putative PBP binding loops; other site
882884005699	ABC-ATPase subunit interface; other site
882884005700	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
882884005701	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
882884005702	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
882884005703	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884005704	Walker A/P-loop; other site
882884005705	ATP binding site [chemical binding]; other site
882884005706	Q-loop/lid; other site
882884005707	ABC transporter signature motif; other site
882884005708	Walker B; other site
882884005709	D-loop; other site
882884005710	H-loop/switch region; other site
882884005711	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
882884005712	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884005713	Walker A/P-loop; other site
882884005714	ATP binding site [chemical binding]; other site
882884005715	Q-loop/lid; other site
882884005716	ABC transporter signature motif; other site
882884005717	Walker B; other site
882884005718	D-loop; other site
882884005719	H-loop/switch region; other site
882884005720	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
882884005721	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
882884005722	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
882884005723	dimer interface [polypeptide binding]; other site
882884005724	putative functional site; other site
882884005725	putative MPT binding site; other site
882884005726	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
882884005727	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
882884005728	ATP binding site [chemical binding]; other site
882884005729	substrate interface [chemical binding]; other site
882884005730	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
882884005731	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884005732	FeS/SAM binding site; other site
882884005733	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
882884005734	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
882884005735	dimer interface [polypeptide binding]; other site
882884005736	active site
882884005737	glycine loop; other site
882884005738	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
882884005739	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884005740	active site
882884005741	motif I; other site
882884005742	motif II; other site
882884005743	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884005744	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
882884005745	Transcriptional regulators [Transcription]; Region: PurR; COG1609
882884005746	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884005747	DNA binding site [nucleotide binding]
882884005748	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
882884005749	ligand binding site [chemical binding]; other site
882884005750	dimerization interface [polypeptide binding]; other site
882884005751	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884005752	D-galactonate transporter; Region: 2A0114; TIGR00893
882884005753	putative substrate translocation pore; other site
882884005754	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
882884005755	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
882884005756	Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599
882884005757	putative active site [active]
882884005758	putative catalytic site [active]
882884005759	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
882884005760	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884005761	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884005762	Walker A/P-loop; other site
882884005763	ATP binding site [chemical binding]; other site
882884005764	ABC transporter signature motif; other site
882884005765	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884005766	Walker B; other site
882884005767	ABC transporter; Region: ABC_tran_2; pfam12848
882884005768	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884005769	L,D-transpeptidase; Provisional; Region: PRK10260
882884005770	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
882884005771	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
882884005772	transmembrane helices; other site
882884005773	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
882884005774	manganese transport regulator MntR; Provisional; Region: PRK11050
882884005775	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
882884005776	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
882884005777	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
882884005778	Sulfatase; Region: Sulfatase; pfam00884
882884005779	outer membrane protein X; Provisional; Region: ompX; PRK09408
882884005780	threonine and homoserine efflux system; Provisional; Region: PRK10532
882884005781	EamA-like transporter family; Region: EamA; pfam00892
882884005782	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
882884005783	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
882884005784	dimerization interface [polypeptide binding]; other site
882884005785	DPS ferroxidase diiron center [ion binding]; other site
882884005786	ion pore; other site
882884005787	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
882884005788	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884005789	substrate binding pocket [chemical binding]; other site
882884005790	membrane-bound complex binding site; other site
882884005791	hinge residues; other site
882884005792	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
882884005793	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884005794	dimer interface [polypeptide binding]; other site
882884005795	conserved gate region; other site
882884005796	putative PBP binding loops; other site
882884005797	ABC-ATPase subunit interface; other site
882884005798	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
882884005799	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
882884005800	Walker A/P-loop; other site
882884005801	ATP binding site [chemical binding]; other site
882884005802	Q-loop/lid; other site
882884005803	ABC transporter signature motif; other site
882884005804	Walker B; other site
882884005805	D-loop; other site
882884005806	H-loop/switch region; other site
882884005807	putative mechanosensitive channel protein; Provisional; Region: PRK11465
882884005808	Mechanosensitive ion channel; Region: MS_channel; pfam00924
882884005809	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
882884005810	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
882884005811	hypothetical protein; Provisional; Region: PRK11019
882884005812	hypothetical protein; Provisional; Region: PRK10259
882884005813	glycosyl transferase family protein; Provisional; Region: PRK08136
882884005814	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
882884005815	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
882884005816	DEAD_2; Region: DEAD_2; pfam06733
882884005817	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
882884005818	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
882884005819	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
882884005820	ATP binding site [chemical binding]; other site
882884005821	Mg++ binding site [ion binding]; other site
882884005822	motif III; other site
882884005823	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884005824	nucleotide binding region [chemical binding]; other site
882884005825	ATP-binding site [chemical binding]; other site
882884005826	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
882884005827	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884005828	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
882884005829	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
882884005830	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
882884005831	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884005832	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
882884005833	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
882884005834	Walker A/P-loop; other site
882884005835	ATP binding site [chemical binding]; other site
882884005836	Q-loop/lid; other site
882884005837	ABC transporter signature motif; other site
882884005838	Walker B; other site
882884005839	D-loop; other site
882884005840	H-loop/switch region; other site
882884005841	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
882884005842	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
882884005843	Walker A/P-loop; other site
882884005844	ATP binding site [chemical binding]; other site
882884005845	Q-loop/lid; other site
882884005846	ABC transporter signature motif; other site
882884005847	Walker B; other site
882884005848	D-loop; other site
882884005849	H-loop/switch region; other site
882884005850	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
882884005851	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
882884005852	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
882884005853	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
882884005854	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
882884005855	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
882884005856	putative catalytic site [active]
882884005857	putative metal binding site [ion binding]; other site
882884005858	putative phosphate binding site [ion binding]; other site
882884005859	cardiolipin synthase 2; Provisional; Region: PRK11263
882884005860	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
882884005861	putative active site [active]
882884005862	catalytic site [active]
882884005863	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
882884005864	putative active site [active]
882884005865	catalytic site [active]
882884005866	Predicted integral membrane protein [Function unknown]; Region: COG0392
882884005867	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
882884005868	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
882884005869	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
882884005870	MoaE homodimer interface [polypeptide binding]; other site
882884005871	MoaD interaction [polypeptide binding]; other site
882884005872	active site residues [active]
882884005873	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
882884005874	MoaE interaction surface [polypeptide binding]; other site
882884005875	MoeB interaction surface [polypeptide binding]; other site
882884005876	thiocarboxylated glycine; other site
882884005877	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
882884005878	trimer interface [polypeptide binding]; other site
882884005879	dimer interface [polypeptide binding]; other site
882884005880	putative active site [active]
882884005881	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
882884005882	MPT binding site; other site
882884005883	trimer interface [polypeptide binding]; other site
882884005884	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
882884005885	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884005886	FeS/SAM binding site; other site
882884005887	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
882884005888	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
882884005889	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
882884005890	putative substrate binding pocket [chemical binding]; other site
882884005891	dimer interface [polypeptide binding]; other site
882884005892	phosphate binding site [ion binding]; other site
882884005893	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
882884005894	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
882884005895	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
882884005896	excinuclease ABC subunit B; Provisional; Region: PRK05298
882884005897	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884005898	ATP binding site [chemical binding]; other site
882884005899	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884005900	nucleotide binding region [chemical binding]; other site
882884005901	ATP-binding site [chemical binding]; other site
882884005902	Ultra-violet resistance protein B; Region: UvrB; pfam12344
882884005903	UvrB/uvrC motif; Region: UVR; pfam02151
882884005904	AAA domain; Region: AAA_26; pfam13500
882884005905	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
882884005906	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
882884005907	active site
882884005908	ADP binding site [chemical binding]; other site
882884005909	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
882884005910	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884005911	S-adenosylmethionine binding site [chemical binding]; other site
882884005912	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
882884005913	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
882884005914	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
882884005915	catalytic residue [active]
882884005916	biotin synthase; Provisional; Region: PRK15108
882884005917	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884005918	FeS/SAM binding site; other site
882884005919	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
882884005920	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
882884005921	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
882884005922	inhibitor-cofactor binding pocket; inhibition site
882884005923	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884005924	catalytic residue [active]
882884005925	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
882884005926	substrate binding site [chemical binding]; other site
882884005927	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
882884005928	active sites [active]
882884005929	tetramer interface [polypeptide binding]; other site
882884005930	urocanate hydratase; Provisional; Region: PRK05414
882884005931	histidine utilization repressor; Provisional; Region: PRK14999
882884005932	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884005933	DNA-binding site [nucleotide binding]; DNA binding site
882884005934	UTRA domain; Region: UTRA; pfam07702
882884005935	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
882884005936	putative active site [active]
882884005937	putative metal binding site [ion binding]; other site
882884005938	imidazolonepropionase; Validated; Region: PRK09356
882884005939	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
882884005940	active site
882884005941	acyl-CoA thioesterase; Provisional; Region: PRK10531
882884005942	putative pectinesterase; Region: PLN02432; cl01911
882884005943	Tetratricopeptide repeat; Region: TPR_16; pfam13432
882884005944	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
882884005945	TPR motif; other site
882884005946	Protein of unknown function (DUF560); Region: DUF560; pfam04575
882884005947	Transferrin binding protein-like solute binding protein; Region: Lipoprotein_5; pfam01298
882884005948	Fimbrial protein; Region: Fimbrial; pfam00419
882884005949	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884005950	Transposase; Region: HTH_Tnp_1; cl17663
882884005951	HTH-like domain; Region: HTH_21; pfam13276
882884005952	Transposase; Region: DEDD_Tnp_IS110; pfam01548
882884005953	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884005954	Major Facilitator Superfamily; Region: MFS_1; pfam07690
882884005955	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
882884005956	IucA / IucC family; Region: IucA_IucC; pfam04183
882884005957	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
882884005958	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
882884005959	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
882884005960	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
882884005961	IucA / IucC family; Region: IucA_IucC; pfam04183
882884005962	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
882884005963	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
882884005964	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
882884005965	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
882884005966	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
882884005967	N-terminal plug; other site
882884005968	ligand-binding site [chemical binding]; other site
882884005969	6-phosphogluconolactonase; Provisional; Region: PRK11028
882884005970	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
882884005971	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884005972	active site
882884005973	motif I; other site
882884005974	motif II; other site
882884005975	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884005976	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
882884005977	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884005978	Walker A/P-loop; other site
882884005979	ATP binding site [chemical binding]; other site
882884005980	Q-loop/lid; other site
882884005981	ABC transporter signature motif; other site
882884005982	Walker B; other site
882884005983	D-loop; other site
882884005984	H-loop/switch region; other site
882884005985	molybdenum-pterin binding domain; Region: Mop; TIGR00638
882884005986	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
882884005987	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884005988	dimer interface [polypeptide binding]; other site
882884005989	conserved gate region; other site
882884005990	putative PBP binding loops; other site
882884005991	ABC-ATPase subunit interface; other site
882884005992	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
882884005993	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884005994	substrate binding pocket [chemical binding]; other site
882884005995	membrane-bound complex binding site; other site
882884005996	hinge residues; other site
882884005997	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
882884005998	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
882884005999	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
882884006000	molybdenum-pterin binding domain; Region: Mop; TIGR00638
882884006001	TOBE domain; Region: TOBE; pfam03459
882884006002	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
882884006003	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884006004	Walker A/P-loop; other site
882884006005	ATP binding site [chemical binding]; other site
882884006006	Q-loop/lid; other site
882884006007	ABC transporter signature motif; other site
882884006008	Walker B; other site
882884006009	D-loop; other site
882884006010	H-loop/switch region; other site
882884006011	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884006012	Walker A/P-loop; other site
882884006013	ATP binding site [chemical binding]; other site
882884006014	Q-loop/lid; other site
882884006015	ABC transporter signature motif; other site
882884006016	Walker B; other site
882884006017	D-loop; other site
882884006018	H-loop/switch region; other site
882884006019	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
882884006020	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
882884006021	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
882884006022	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
882884006023	dimer interface [polypeptide binding]; other site
882884006024	active site
882884006025	galactokinase; Provisional; Region: PRK05101
882884006026	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
882884006027	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
882884006028	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
882884006029	active site
882884006030	catalytic residues [active]
882884006031	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
882884006032	putative active site [active]
882884006033	YdjC motif; other site
882884006034	Mg binding site [ion binding]; other site
882884006035	putative homodimer interface [polypeptide binding]; other site
882884006036	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
882884006037	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
882884006038	NAD binding site [chemical binding]; other site
882884006039	sugar binding site [chemical binding]; other site
882884006040	divalent metal binding site [ion binding]; other site
882884006041	tetramer (dimer of dimers) interface [polypeptide binding]; other site
882884006042	dimer interface [polypeptide binding]; other site
882884006043	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
882884006044	Cupin domain; Region: Cupin_2; pfam07883
882884006045	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884006046	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
882884006047	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
882884006048	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
882884006049	catalytic core [active]
882884006050	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
882884006051	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
882884006052	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
882884006053	YbgS-like protein; Region: YbgS; pfam13985
882884006054	zinc transporter ZitB; Provisional; Region: PRK03557
882884006055	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
882884006056	quinolinate synthetase; Provisional; Region: PRK09375
882884006057	tol-pal system protein YbgF; Provisional; Region: PRK10803
882884006058	Tetratricopeptide repeat; Region: TPR_6; pfam13174
882884006059	Tetratricopeptide repeat; Region: TPR_6; pfam13174
882884006060	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
882884006061	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
882884006062	ligand binding site [chemical binding]; other site
882884006063	translocation protein TolB; Provisional; Region: tolB; PRK03629
882884006064	TolB amino-terminal domain; Region: TolB_N; pfam04052
882884006065	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
882884006066	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
882884006067	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
882884006068	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
882884006069	TolA C-terminal; Region: TolA; pfam06519
882884006070	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
882884006071	colicin uptake protein TolR; Provisional; Region: PRK11024
882884006072	colicin uptake protein TolQ; Provisional; Region: PRK10801
882884006073	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
882884006074	active site
882884006075	hypothetical protein; Provisional; Region: PRK10588
882884006076	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
882884006077	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
882884006078	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
882884006079	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
882884006080	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
882884006081	B12 binding domain of glutamate mutase (Glm). Glutamate mutase catalysis the conversion of (S)-glutamate with (2S,3S)-3-methylaspartate. The rearrangement reaction is initiated by the extraction of a hydrogen from the protein-bound substrate by a 5'...; Region: Glm_B12_BD; cd02072
882884006082	B12 binding site [chemical binding]; other site
882884006083	heterodimer interface [polypeptide binding]; other site
882884006084	cobalt ligand [ion binding]; other site
882884006085	conserved hypothetical protein; Region: glmL_fam; TIGR01319
882884006086	Coenzyme B12-dependent glutamate mutase epsilon subunit-like family; contains proteins similar to Clostridium cochlearium glutamate mutase (Glm) and Streptomyces tendae Tu901 NikV. Glm catalyzes a carbon-skeleton rearrangement of L-glutamate to...; Region: Glm_e; cd00245
882884006087	substrate binding site [chemical binding]; other site
882884006088	B12 cofactor binding site [chemical binding]; other site
882884006089	heterodimer (sigma-epsilon) interface [polypeptide binding]; other site
882884006090	homodimer (epsilon-epsilon) interface [polypeptide binding]; other site
882884006091	Methylaspartate ammonia-lyase [Amino acid transport and metabolism]; Region: Mal; COG3799
882884006092	Methylaspartate ammonia lyase (3-methylaspartase, MAL) is a homodimeric enzyme, catalyzing the magnesium-dependent reversible alpha,beta-elimination of ammonia from L-threo-(2S,3S)-3-methylaspartic acid to mesaconic acid. This reaction is part of the...; Region: MAL; cd03314
882884006093	dimer interface [polypeptide binding]; other site
882884006094	active site
882884006095	Protein of unknown function (DUF1446); Region: DUF1446; pfam07287
882884006096	Domain of unknown function (DUF4387); Region: DUF4387; pfam14330
882884006097	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
882884006098	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
882884006099	putative fumarate hydratase; Provisional; Region: PRK15392
882884006100	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
882884006101	Fumarase C-terminus; Region: Fumerase_C; pfam05683
882884006102	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
882884006103	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
882884006104	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
882884006105	homodimer interface [polypeptide binding]; other site
882884006106	Walker A motif; other site
882884006107	ATP binding site [chemical binding]; other site
882884006108	hydroxycobalamin binding site [chemical binding]; other site
882884006109	Walker B motif; other site
882884006110	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884006111	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
882884006112	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884006113	dimerization interface [polypeptide binding]; other site
882884006114	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
882884006115	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884006116	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
882884006117	CoA binding domain; Region: CoA_binding; smart00881
882884006118	CoA-ligase; Region: Ligase_CoA; pfam00549
882884006119	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
882884006120	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
882884006121	CoA-ligase; Region: Ligase_CoA; pfam00549
882884006122	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
882884006123	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
882884006124	E3 interaction surface; other site
882884006125	lipoyl attachment site [posttranslational modification]; other site
882884006126	e3 binding domain; Region: E3_binding; pfam02817
882884006127	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
882884006128	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
882884006129	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
882884006130	TPP-binding site [chemical binding]; other site
882884006131	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
882884006132	dimer interface [polypeptide binding]; other site
882884006133	PYR/PP interface [polypeptide binding]; other site
882884006134	TPP binding site [chemical binding]; other site
882884006135	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
882884006136	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
882884006137	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
882884006138	L-aspartate oxidase; Provisional; Region: PRK06175
882884006139	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
882884006140	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
882884006141	SdhC subunit interface [polypeptide binding]; other site
882884006142	proximal heme binding site [chemical binding]; other site
882884006143	cardiolipin binding site; other site
882884006144	Iron-sulfur protein interface; other site
882884006145	proximal quinone binding site [chemical binding]; other site
882884006146	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
882884006147	Iron-sulfur protein interface; other site
882884006148	proximal quinone binding site [chemical binding]; other site
882884006149	SdhD (CybS) interface [polypeptide binding]; other site
882884006150	proximal heme binding site [chemical binding]; other site
882884006151	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
882884006152	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
882884006153	dimer interface [polypeptide binding]; other site
882884006154	active site
882884006155	citrylCoA binding site [chemical binding]; other site
882884006156	NADH binding [chemical binding]; other site
882884006157	cationic pore residues; other site
882884006158	oxalacetate/citrate binding site [chemical binding]; other site
882884006159	coenzyme A binding site [chemical binding]; other site
882884006160	catalytic triad [active]
882884006161	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
882884006162	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
882884006163	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
882884006164	endonuclease VIII; Provisional; Region: PRK10445
882884006165	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
882884006166	DNA binding site [nucleotide binding]
882884006167	catalytic residue [active]
882884006168	putative catalytic residues [active]
882884006169	H2TH interface [polypeptide binding]; other site
882884006170	intercalation triad [nucleotide binding]; other site
882884006171	substrate specificity determining residue; other site
882884006172	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
882884006173	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
882884006174	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
882884006175	putative active site [active]
882884006176	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
882884006177	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
882884006178	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
882884006179	Uncharacterized conserved protein [Function unknown]; Region: COG0327
882884006180	metal-binding protein; Provisional; Region: PRK10799
882884006181	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
882884006182	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884006183	putative substrate translocation pore; other site
882884006184	POT family; Region: PTR2; pfam00854
882884006185	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
882884006186	DNA photolyase; Region: DNA_photolyase; pfam00875
882884006187	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
882884006188	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
882884006189	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
882884006190	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
882884006191	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
882884006192	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
882884006193	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
882884006194	sensor protein KdpD; Provisional; Region: PRK10490
882884006195	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
882884006196	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
882884006197	Ligand Binding Site [chemical binding]; other site
882884006198	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
882884006199	GAF domain; Region: GAF_3; pfam13492
882884006200	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884006201	dimer interface [polypeptide binding]; other site
882884006202	phosphorylation site [posttranslational modification]
882884006203	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884006204	ATP binding site [chemical binding]; other site
882884006205	Mg2+ binding site [ion binding]; other site
882884006206	G-X-G motif; other site
882884006207	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
882884006208	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884006209	active site
882884006210	phosphorylation site [posttranslational modification]
882884006211	intermolecular recognition site; other site
882884006212	dimerization interface [polypeptide binding]; other site
882884006213	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884006214	DNA binding site [nucleotide binding]
882884006215	ornithine decarboxylase; Provisional; Region: PRK13578
882884006216	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
882884006217	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
882884006218	homodimer interface [polypeptide binding]; other site
882884006219	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884006220	catalytic residue [active]
882884006221	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
882884006222	putrescine transporter; Provisional; Region: potE; PRK10655
882884006223	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
882884006224	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
882884006225	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
882884006226	active site
882884006227	substrate binding site [chemical binding]; other site
882884006228	metal binding site [ion binding]; metal-binding site
882884006229	replication initiation regulator SeqA; Provisional; Region: PRK11187
882884006230	acyl-CoA esterase; Provisional; Region: PRK10673
882884006231	PGAP1-like protein; Region: PGAP1; pfam07819
882884006232	LexA regulated protein; Provisional; Region: PRK11675
882884006233	flavodoxin FldA; Validated; Region: PRK09267
882884006234	ferric uptake regulator; Provisional; Region: fur; PRK09462
882884006235	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
882884006236	metal binding site 2 [ion binding]; metal-binding site
882884006237	putative DNA binding helix; other site
882884006238	metal binding site 1 [ion binding]; metal-binding site
882884006239	dimer interface [polypeptide binding]; other site
882884006240	structural Zn2+ binding site [ion binding]; other site
882884006241	tricarballylate utilization protein B; Provisional; Region: PRK15033
882884006242	citrate-proton symporter; Provisional; Region: PRK15075
882884006243	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884006244	putative substrate translocation pore; other site
882884006245	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
882884006246	YbfN-like lipoprotein; Region: YbfN; pfam13982
882884006247	outer membrane porin, OprD family; Region: OprD; pfam03573
882884006248	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
882884006249	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
882884006250	active site
882884006251	HIGH motif; other site
882884006252	nucleotide binding site [chemical binding]; other site
882884006253	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
882884006254	KMSKS motif; other site
882884006255	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
882884006256	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
882884006257	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
882884006258	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
882884006259	active site turn [active]
882884006260	phosphorylation site [posttranslational modification]
882884006261	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
882884006262	HPr interaction site; other site
882884006263	glycerol kinase (GK) interaction site [polypeptide binding]; other site
882884006264	active site
882884006265	phosphorylation site [posttranslational modification]
882884006266	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
882884006267	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
882884006268	active site
882884006269	trimer interface [polypeptide binding]; other site
882884006270	allosteric site; other site
882884006271	active site lid [active]
882884006272	hexamer (dimer of trimers) interface [polypeptide binding]; other site
882884006273	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
882884006274	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
882884006275	active site
882884006276	dimer interface [polypeptide binding]; other site
882884006277	MarR family; Region: MarR; pfam01047
882884006278	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
882884006279	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
882884006280	nucleotide binding site [chemical binding]; other site
882884006281	UMP phosphatase; Provisional; Region: PRK10444
882884006282	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884006283	active site
882884006284	motif I; other site
882884006285	motif II; other site
882884006286	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884006287	asparagine synthetase B; Provisional; Region: asnB; PRK09431
882884006288	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
882884006289	active site
882884006290	dimer interface [polypeptide binding]; other site
882884006291	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
882884006292	Ligand Binding Site [chemical binding]; other site
882884006293	Molecular Tunnel; other site
882884006294	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
882884006295	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
882884006296	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
882884006297	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
882884006298	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884006299	FeS/SAM binding site; other site
882884006300	TRAM domain; Region: TRAM; pfam01938
882884006301	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
882884006302	PhoH-like protein; Region: PhoH; pfam02562
882884006303	metal-binding heat shock protein; Provisional; Region: PRK00016
882884006304	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
882884006305	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
882884006306	Transporter associated domain; Region: CorC_HlyC; smart01091
882884006307	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
882884006308	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
882884006309	putative active site [active]
882884006310	catalytic triad [active]
882884006311	putative dimer interface [polypeptide binding]; other site
882884006312	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
882884006313	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884006314	substrate binding pocket [chemical binding]; other site
882884006315	membrane-bound complex binding site; other site
882884006316	hinge residues; other site
882884006317	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
882884006318	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884006319	dimer interface [polypeptide binding]; other site
882884006320	conserved gate region; other site
882884006321	putative PBP binding loops; other site
882884006322	ABC-ATPase subunit interface; other site
882884006323	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
882884006324	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884006325	dimer interface [polypeptide binding]; other site
882884006326	conserved gate region; other site
882884006327	putative PBP binding loops; other site
882884006328	ABC-ATPase subunit interface; other site
882884006329	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
882884006330	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
882884006331	Walker A/P-loop; other site
882884006332	ATP binding site [chemical binding]; other site
882884006333	Q-loop/lid; other site
882884006334	ABC transporter signature motif; other site
882884006335	Walker B; other site
882884006336	D-loop; other site
882884006337	H-loop/switch region; other site
882884006338	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
882884006339	active site
882884006340	tetramer interface [polypeptide binding]; other site
882884006341	hypothetical protein; Provisional; Region: PRK11032
882884006342	SPX domain; Region: SPX; pfam03105
882884006343	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
882884006344	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
882884006345	HIGH motif; other site
882884006346	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
882884006347	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
882884006348	active site
882884006349	KMSKS motif; other site
882884006350	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
882884006351	tRNA binding surface [nucleotide binding]; other site
882884006352	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
882884006353	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
882884006354	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
882884006355	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
882884006356	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
882884006357	active site
882884006358	(T/H)XGH motif; other site
882884006359	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
882884006360	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884006361	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884006362	homodimer interface [polypeptide binding]; other site
882884006363	catalytic residue [active]
882884006364	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
882884006365	catalytic core [active]
882884006366	ribosome-associated protein; Provisional; Region: PRK11538
882884006367	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
882884006368	penicillin-binding protein 2; Provisional; Region: PRK10795
882884006369	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
882884006370	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
882884006371	cell wall shape-determining protein; Provisional; Region: PRK10794
882884006372	rare lipoprotein A; Provisional; Region: PRK10672
882884006373	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
882884006374	Sporulation related domain; Region: SPOR; pfam05036
882884006375	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
882884006376	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
882884006377	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
882884006378	hypothetical protein; Provisional; Region: PRK04998
882884006379	lipoate-protein ligase B; Provisional; Region: PRK14342
882884006380	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
882884006381	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884006382	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
882884006383	substrate binding pocket [chemical binding]; other site
882884006384	dimerization interface [polypeptide binding]; other site
882884006385	lipoyl synthase; Provisional; Region: PRK05481
882884006386	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884006387	FeS/SAM binding site; other site
882884006388	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
882884006389	Predicted amidohydrolase [General function prediction only]; Region: COG0388
882884006390	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
882884006391	putative active site [active]
882884006392	catalytic triad [active]
882884006393	putative dimer interface [polypeptide binding]; other site
882884006394	chromosome condensation membrane protein; Provisional; Region: PRK14196
882884006395	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
882884006396	DNA-binding site [nucleotide binding]; DNA binding site
882884006397	RNA-binding motif; other site
882884006398	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
882884006399	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
882884006400	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
882884006401	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
882884006402	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884006403	active site
882884006404	phosphorylation site [posttranslational modification]
882884006405	intermolecular recognition site; other site
882884006406	dimerization interface [polypeptide binding]; other site
882884006407	Transcriptional regulator; Region: CitT; pfam12431
882884006408	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
882884006409	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
882884006410	putative active site [active]
882884006411	heme pocket [chemical binding]; other site
882884006412	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884006413	ATP binding site [chemical binding]; other site
882884006414	Mg2+ binding site [ion binding]; other site
882884006415	G-X-G motif; other site
882884006416	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
882884006417	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
882884006418	putative active site [active]
882884006419	(T/H)XGH motif; other site
882884006420	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
882884006421	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
882884006422	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
882884006423	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
882884006424	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
882884006425	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
882884006426	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
882884006427	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
882884006428	transmembrane helices; other site
882884006429	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
882884006430	B1 nucleotide binding pocket [chemical binding]; other site
882884006431	B2 nucleotide binding pocket [chemical binding]; other site
882884006432	CAS motifs; other site
882884006433	active site
882884006434	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
882884006435	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
882884006436	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
882884006437	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
882884006438	NAD binding site [chemical binding]; other site
882884006439	catalytic Zn binding site [ion binding]; other site
882884006440	structural Zn binding site [ion binding]; other site
882884006441	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
882884006442	Ligand Binding Site [chemical binding]; other site
882884006443	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
882884006444	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
882884006445	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
882884006446	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
882884006447	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
882884006448	putative [4Fe-4S] binding site [ion binding]; other site
882884006449	putative molybdopterin cofactor binding site [chemical binding]; other site
882884006450	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
882884006451	molybdopterin cofactor binding site; other site
882884006452	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
882884006453	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
882884006454	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
882884006455	catalytic residue [active]
882884006456	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
882884006457	catalytic residues [active]
882884006458	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
882884006459	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884006460	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
882884006461	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
882884006462	dimer interface [polypeptide binding]; other site
882884006463	decamer (pentamer of dimers) interface [polypeptide binding]; other site
882884006464	catalytic triad [active]
882884006465	peroxidatic and resolving cysteines [active]
882884006466	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
882884006467	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
882884006468	dimerization domain [polypeptide binding]; other site
882884006469	dimer interface [polypeptide binding]; other site
882884006470	catalytic residues [active]
882884006471	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884006472	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884006473	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884006474	dimerization interface [polypeptide binding]; other site
882884006475	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
882884006476	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
882884006477	Active Sites [active]
882884006478	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
882884006479	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
882884006480	ParB-like nuclease domain; Region: ParBc; pfam02195
882884006481	methionine aminotransferase; Validated; Region: PRK09082
882884006482	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884006483	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884006484	homodimer interface [polypeptide binding]; other site
882884006485	catalytic residue [active]
882884006486	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
882884006487	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
882884006488	putative active site [active]
882884006489	metal binding site [ion binding]; metal-binding site
882884006490	Uncharacterized small protein [Function unknown]; Region: COG2879
882884006491	carbon starvation protein A; Provisional; Region: PRK15015
882884006492	Carbon starvation protein CstA; Region: CstA; pfam02554
882884006493	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
882884006494	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
882884006495	CoenzymeA binding site [chemical binding]; other site
882884006496	subunit interaction site [polypeptide binding]; other site
882884006497	PHB binding site; other site
882884006498	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
882884006499	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
882884006500	putative NAD(P) binding site [chemical binding]; other site
882884006501	active site
882884006502	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
882884006503	hydrophobic substrate binding pocket; other site
882884006504	Isochorismatase family; Region: Isochorismatase; pfam00857
882884006505	active site
882884006506	conserved cis-peptide bond; other site
882884006507	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
882884006508	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
882884006509	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
882884006510	acyl-activating enzyme (AAE) consensus motif; other site
882884006511	active site
882884006512	AMP binding site [chemical binding]; other site
882884006513	substrate binding site [chemical binding]; other site
882884006514	isochorismate synthase EntC; Provisional; Region: PRK15016
882884006515	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
882884006516	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
882884006517	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
882884006518	siderophore binding site; other site
882884006519	enterobactin exporter EntS; Provisional; Region: PRK10489
882884006520	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884006521	putative substrate translocation pore; other site
882884006522	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
882884006523	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
882884006524	ABC-ATPase subunit  interface; other site
882884006525	dimer interface [polypeptide binding]; other site
882884006526	putative PBP binding regions; other site
882884006527	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
882884006528	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
882884006529	ABC-ATPase subunit  interface; other site
882884006530	dimer interface [polypeptide binding]; other site
882884006531	putative PBP binding regions; other site
882884006532	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
882884006533	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
882884006534	Walker A/P-loop; other site
882884006535	ATP binding site [chemical binding]; other site
882884006536	Q-loop/lid; other site
882884006537	ABC transporter signature motif; other site
882884006538	Walker B; other site
882884006539	D-loop; other site
882884006540	H-loop/switch region; other site
882884006541	LPS O-antigen length regulator; Provisional; Region: PRK10381
882884006542	Chain length determinant protein; Region: Wzz; pfam02706
882884006543	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
882884006544	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
882884006545	acyl-activating enzyme (AAE) consensus motif; other site
882884006546	AMP binding site [chemical binding]; other site
882884006547	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
882884006548	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
882884006549	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
882884006550	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
882884006551	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
882884006552	outer membrane receptor FepA; Provisional; Region: PRK13524
882884006553	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
882884006554	N-terminal plug; other site
882884006555	ligand-binding site [chemical binding]; other site
882884006556	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
882884006557	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
882884006558	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
882884006559	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
882884006560	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
882884006561	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
882884006562	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884006563	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
882884006564	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884006565	hypothetical protein; Provisional; Region: PRK10250
882884006566	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
882884006567	dimer interface [polypeptide binding]; other site
882884006568	FMN binding site [chemical binding]; other site
882884006569	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
882884006570	active pocket/dimerization site; other site
882884006571	active site
882884006572	phosphorylation site [posttranslational modification]
882884006573	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
882884006574	active site
882884006575	phosphorylation site [posttranslational modification]
882884006576	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
882884006577	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
882884006578	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
882884006579	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
882884006580	dimer interface [polypeptide binding]; other site
882884006581	active site
882884006582	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
882884006583	dimer interface [polypeptide binding]; other site
882884006584	active site
882884006585	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
882884006586	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
882884006587	putative active site [active]
882884006588	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
882884006589	dimer interface [polypeptide binding]; other site
882884006590	active site
882884006591	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
882884006592	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884006593	ATP binding site [chemical binding]; other site
882884006594	Walker B motif; other site
882884006595	arginine finger; other site
882884006596	Transcriptional antiterminator [Transcription]; Region: COG3933
882884006597	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
882884006598	active pocket/dimerization site; other site
882884006599	active site
882884006600	phosphorylation site [posttranslational modification]
882884006601	PRD domain; Region: PRD; pfam00874
882884006602	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
882884006603	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
882884006604	active site
882884006605	oxyanion hole [active]
882884006606	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
882884006607	catalytic triad [active]
882884006608	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
882884006609	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
882884006610	Mechanosensitive ion channel; Region: MS_channel; pfam00924
882884006611	phenylalanine transporter; Provisional; Region: PRK10249
882884006612	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
882884006613	Predicted membrane protein [Function unknown]; Region: COG3059
882884006614	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884006615	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
882884006616	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884006617	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
882884006618	Cupin; Region: Cupin_6; pfam12852
882884006619	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
882884006620	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884006621	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
882884006622	Autotransporter beta-domain; Region: Autotransporter; pfam03797
882884006623	Lyase, N terminal; Region: Lyase_N; pfam09092
882884006624	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
882884006625	substrate binding site [chemical binding]; other site
882884006626	catalytic residues [active]
882884006627	Winged helix-turn helix; Region: HTH_29; pfam13551
882884006628	Homeodomain-like domain; Region: HTH_23; cl17451
882884006629	CdtB, the catalytic DNase I-like subunit of cytolethal distending toxin (CDT) protein; Region: CdtB; cd09081
882884006630	putative catalytic site [active]
882884006631	CdtC interface [polypeptide binding]; other site
882884006632	heterotrimer interface [polypeptide binding]; other site
882884006633	CdtA interface [polypeptide binding]; other site
882884006634	putative metal binding site [ion binding]; other site
882884006635	putative phosphate binding site [ion binding]; other site
882884006636	Protein of unknown function (DUF1353); Region: DUF1353; pfam07087
882884006637	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
882884006638	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
882884006639	pertussis toxin-like subunit ArtA; Provisional; Region: PRK15272
882884006640	subtilase cytotoxin subunit B; Provisional; Region: PRK15266
882884006641	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
882884006642	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
882884006643	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
882884006644	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
882884006645	Protein of unknown function (DUF551); Region: DUF551; pfam04448
882884006646	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
882884006647	Interdomain contacts; other site
882884006648	Cytokine receptor motif; other site
882884006649	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
882884006650	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
882884006651	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
882884006652	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
882884006653	Autotransporter beta-domain; Region: Autotransporter; pfam03797
882884006654	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
882884006655	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
882884006656	Fimbrial protein; Region: Fimbrial; cl01416
882884006657	outer membrane usher protein FimD; Provisional; Region: PRK15198
882884006658	PapC N-terminal domain; Region: PapC_N; pfam13954
882884006659	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
882884006660	PapC C-terminal domain; Region: PapC_C; pfam13953
882884006661	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
882884006662	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
882884006663	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
882884006664	fimbrial protein FimI; Provisional; Region: PRK15200
882884006665	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
882884006666	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
882884006667	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
882884006668	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
882884006669	homodimer interface [polypeptide binding]; other site
882884006670	NADP binding site [chemical binding]; other site
882884006671	substrate binding site [chemical binding]; other site
882884006672	ribosome-associated protein; Provisional; Region: PRK11507
882884006673	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
882884006674	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
882884006675	active site
882884006676	HIGH motif; other site
882884006677	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
882884006678	KMSKS motif; other site
882884006679	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
882884006680	tRNA binding surface [nucleotide binding]; other site
882884006681	anticodon binding site; other site
882884006682	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
882884006683	substrate binding site [chemical binding]; other site
882884006684	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
882884006685	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
882884006686	putative active site [active]
882884006687	putative metal binding site [ion binding]; other site
882884006688	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
882884006689	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
882884006690	ATP-grasp domain; Region: ATP-grasp; pfam02222
882884006691	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
882884006692	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
882884006693	active site residue [active]
882884006694	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884006695	dimer interface [polypeptide binding]; other site
882884006696	conserved gate region; other site
882884006697	ABC-ATPase subunit interface; other site
882884006698	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
882884006699	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
882884006700	Walker A/P-loop; other site
882884006701	ATP binding site [chemical binding]; other site
882884006702	Q-loop/lid; other site
882884006703	ABC transporter signature motif; other site
882884006704	Walker B; other site
882884006705	D-loop; other site
882884006706	H-loop/switch region; other site
882884006707	NIL domain; Region: NIL; pfam09383
882884006708	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
882884006709	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
882884006710	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
882884006711	FtsX-like permease family; Region: FtsX; pfam02687
882884006712	FtsX-like permease family; Region: FtsX; pfam02687
882884006713	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
882884006714	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
882884006715	Walker A/P-loop; other site
882884006716	ATP binding site [chemical binding]; other site
882884006717	Q-loop/lid; other site
882884006718	ABC transporter signature motif; other site
882884006719	Walker B; other site
882884006720	D-loop; other site
882884006721	H-loop/switch region; other site
882884006722	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
882884006723	active site
882884006724	catalytic triad [active]
882884006725	oxyanion hole [active]
882884006726	switch loop; other site
882884006727	oxidoreductase; Provisional; Region: PRK08017
882884006728	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
882884006729	NADP binding site [chemical binding]; other site
882884006730	active site
882884006731	steroid binding site; other site
882884006732	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
882884006733	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
882884006734	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
882884006735	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
882884006736	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
882884006737	Walker A/P-loop; other site
882884006738	ATP binding site [chemical binding]; other site
882884006739	Q-loop/lid; other site
882884006740	ABC transporter signature motif; other site
882884006741	Walker B; other site
882884006742	D-loop; other site
882884006743	H-loop/switch region; other site
882884006744	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
882884006745	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
882884006746	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
882884006747	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
882884006748	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
882884006749	DNA binding residues [nucleotide binding]
882884006750	dimer interface [polypeptide binding]; other site
882884006751	copper binding site [ion binding]; other site
882884006752	copper exporting ATPase; Provisional; Region: copA; PRK10671
882884006753	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
882884006754	metal-binding site [ion binding]
882884006755	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
882884006756	metal-binding site [ion binding]
882884006757	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
882884006758	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884006759	motif II; other site
882884006760	TraB family; Region: TraB; cl12050
882884006761	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
882884006762	putative deacylase active site [active]
882884006763	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
882884006764	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
882884006765	active site
882884006766	metal binding site [ion binding]; metal-binding site
882884006767	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
882884006768	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884006769	Major Facilitator Superfamily; Region: MFS_1; pfam07690
882884006770	putative substrate translocation pore; other site
882884006771	putative cation:proton antiport protein; Provisional; Region: PRK10669
882884006772	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
882884006773	TrkA-N domain; Region: TrkA_N; pfam02254
882884006774	inosine/guanosine kinase; Provisional; Region: PRK15074
882884006775	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
882884006776	acetyl esterase; Provisional; Region: PRK10162
882884006777	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
882884006778	ferrochelatase; Reviewed; Region: hemH; PRK00035
882884006779	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
882884006780	C-terminal domain interface [polypeptide binding]; other site
882884006781	active site
882884006782	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
882884006783	active site
882884006784	N-terminal domain interface [polypeptide binding]; other site
882884006785	adenylate kinase; Reviewed; Region: adk; PRK00279
882884006786	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
882884006787	AMP-binding site [chemical binding]; other site
882884006788	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
882884006789	heat shock protein 90; Provisional; Region: PRK05218
882884006790	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884006791	ATP binding site [chemical binding]; other site
882884006792	Mg2+ binding site [ion binding]; other site
882884006793	G-X-G motif; other site
882884006794	recombination protein RecR; Reviewed; Region: recR; PRK00076
882884006795	RecR protein; Region: RecR; pfam02132
882884006796	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
882884006797	putative active site [active]
882884006798	putative metal-binding site [ion binding]; other site
882884006799	tetramer interface [polypeptide binding]; other site
882884006800	hypothetical protein; Validated; Region: PRK00153
882884006801	Dnax ribosomal frameshifting element
882884006802	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
882884006803	active site
882884006804	hypothetical protein; Provisional; Region: PRK10527
882884006805	primosomal replication protein N''; Provisional; Region: PRK10093
882884006806	hypothetical protein; Provisional; Region: PRK11038
882884006807	hypothetical protein; Provisional; Region: PRK11281
882884006808	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
882884006809	Mechanosensitive ion channel; Region: MS_channel; pfam00924
882884006810	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
882884006811	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884006812	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
882884006813	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
882884006814	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884006815	Animal heme peroxidases and related proteins; Region: An_peroxidase_like; cl14561
882884006816	substrate binding site [chemical binding]; other site
882884006817	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
882884006818	Protein export membrane protein; Region: SecD_SecF; cl14618
882884006819	Protein export membrane protein; Region: SecD_SecF; cl14618
882884006820	Hha toxicity attenuator; Provisional; Region: PRK10667
882884006821	gene expression modulator; Provisional; Region: PRK10945
882884006822	maltose O-acetyltransferase; Provisional; Region: PRK10092
882884006823	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
882884006824	active site
882884006825	substrate binding site [chemical binding]; other site
882884006826	trimer interface [polypeptide binding]; other site
882884006827	CoA binding site [chemical binding]; other site
882884006828	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
882884006829	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
882884006830	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
882884006831	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
882884006832	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
882884006833	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
882884006834	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
882884006835	DNA binding site [nucleotide binding]
882884006836	active site
882884006837	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
882884006838	acyl-CoA thioesterase II; Provisional; Region: PRK10526
882884006839	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
882884006840	active site
882884006841	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
882884006842	catalytic triad [active]
882884006843	dimer interface [polypeptide binding]; other site
882884006844	ammonium transporter; Provisional; Region: PRK10666
882884006845	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
882884006846	Nitrogen regulatory protein P-II; Region: P-II; smart00938
882884006847	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
882884006848	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
882884006849	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884006850	Walker A/P-loop; other site
882884006851	ATP binding site [chemical binding]; other site
882884006852	Q-loop/lid; other site
882884006853	ABC transporter signature motif; other site
882884006854	Walker B; other site
882884006855	D-loop; other site
882884006856	H-loop/switch region; other site
882884006857	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
882884006858	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
882884006859	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884006860	Walker A/P-loop; other site
882884006861	ATP binding site [chemical binding]; other site
882884006862	Q-loop/lid; other site
882884006863	ABC transporter signature motif; other site
882884006864	Walker B; other site
882884006865	D-loop; other site
882884006866	H-loop/switch region; other site
882884006867	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
882884006868	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
882884006869	putative DNA binding site [nucleotide binding]; other site
882884006870	putative Zn2+ binding site [ion binding]; other site
882884006871	AsnC family; Region: AsnC_trans_reg; pfam01037
882884006872	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
882884006873	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
882884006874	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
882884006875	catalytic residue [active]
882884006876	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
882884006877	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884006878	active site
882884006879	motif I; other site
882884006880	motif II; other site
882884006881	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
882884006882	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
882884006883	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
882884006884	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
882884006885	Ligand Binding Site [chemical binding]; other site
882884006886	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
882884006887	active site
882884006888	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
882884006889	periplasmic folding chaperone; Provisional; Region: PRK10788
882884006890	SurA N-terminal domain; Region: SurA_N_3; cl07813
882884006891	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
882884006892	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
882884006893	IHF dimer interface [polypeptide binding]; other site
882884006894	IHF - DNA interface [nucleotide binding]; other site
882884006895	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
882884006896	Found in ATP-dependent protease La (LON); Region: LON; smart00464
882884006897	Found in ATP-dependent protease La (LON); Region: LON; smart00464
882884006898	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884006899	Walker A motif; other site
882884006900	ATP binding site [chemical binding]; other site
882884006901	Walker B motif; other site
882884006902	arginine finger; other site
882884006903	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
882884006904	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
882884006905	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
882884006906	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884006907	Walker A motif; other site
882884006908	ATP binding site [chemical binding]; other site
882884006909	Walker B motif; other site
882884006910	Iron permease FTR1 family; Region: FTR1; cl00475
882884006911	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
882884006912	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
882884006913	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
882884006914	oligomer interface [polypeptide binding]; other site
882884006915	active site residues [active]
882884006916	trigger factor; Provisional; Region: tig; PRK01490
882884006917	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
882884006918	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
882884006919	transcriptional regulator BolA; Provisional; Region: PRK11628
882884006920	hypothetical protein; Provisional; Region: PRK11627
882884006921	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
882884006922	muropeptide transporter; Reviewed; Region: ampG; PRK11902
882884006923	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884006924	putative substrate translocation pore; other site
882884006925	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
882884006926	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
882884006927	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
882884006928	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
882884006929	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
882884006930	D-pathway; other site
882884006931	Putative ubiquinol binding site [chemical binding]; other site
882884006932	Low-spin heme (heme b) binding site [chemical binding]; other site
882884006933	Putative water exit pathway; other site
882884006934	Binuclear center (heme o3/CuB) [ion binding]; other site
882884006935	K-pathway; other site
882884006936	Putative proton exit pathway; other site
882884006937	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
882884006938	Subunit I/III interface [polypeptide binding]; other site
882884006939	Subunit III/IV interface [polypeptide binding]; other site
882884006940	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
882884006941	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
882884006942	UbiA prenyltransferase family; Region: UbiA; pfam01040
882884006943	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884006944	Major Facilitator Superfamily; Region: MFS_1; pfam07690
882884006945	putative substrate translocation pore; other site
882884006946	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
882884006947	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
882884006948	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
882884006949	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
882884006950	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
882884006951	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
882884006952	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
882884006953	conserved cys residue [active]
882884006954	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
882884006955	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
882884006956	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
882884006957	Ligand Binding Site [chemical binding]; other site
882884006958	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
882884006959	active site residue [active]
882884006960	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
882884006961	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
882884006962	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
882884006963	substrate binding pocket [chemical binding]; other site
882884006964	chain length determination region; other site
882884006965	substrate-Mg2+ binding site; other site
882884006966	catalytic residues [active]
882884006967	aspartate-rich region 1; other site
882884006968	active site lid residues [active]
882884006969	aspartate-rich region 2; other site
882884006970	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
882884006971	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
882884006972	TPP-binding site; other site
882884006973	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
882884006974	PYR/PP interface [polypeptide binding]; other site
882884006975	dimer interface [polypeptide binding]; other site
882884006976	TPP binding site [chemical binding]; other site
882884006977	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
882884006978	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
882884006979	tetramer interfaces [polypeptide binding]; other site
882884006980	binuclear metal-binding site [ion binding]; other site
882884006981	thiamine monophosphate kinase; Provisional; Region: PRK05731
882884006982	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
882884006983	ATP binding site [chemical binding]; other site
882884006984	dimerization interface [polypeptide binding]; other site
882884006985	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
882884006986	putative RNA binding site [nucleotide binding]; other site
882884006987	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
882884006988	homopentamer interface [polypeptide binding]; other site
882884006989	active site
882884006990	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
882884006991	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
882884006992	catalytic motif [active]
882884006993	Zn binding site [ion binding]; other site
882884006994	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
882884006995	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
882884006996	ATP cone domain; Region: ATP-cone; pfam03477
882884006997	hypothetical protein; Provisional; Region: PRK11530
882884006998	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
882884006999	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
882884007000	active site
882884007001	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
882884007002	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
882884007003	Protein export membrane protein; Region: SecD_SecF; pfam02355
882884007004	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
882884007005	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
882884007006	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
882884007007	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
882884007008	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
882884007009	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
882884007010	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
882884007011	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
882884007012	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
882884007013	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
882884007014	peroxidase; Provisional; Region: PRK15000
882884007015	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
882884007016	dimer interface [polypeptide binding]; other site
882884007017	decamer (pentamer of dimers) interface [polypeptide binding]; other site
882884007018	catalytic triad [active]
882884007019	peroxidatic and resolving cysteines [active]
882884007020	maltodextrin glucosidase; Provisional; Region: PRK10785
882884007021	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
882884007022	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
882884007023	active site
882884007024	homodimer interface [polypeptide binding]; other site
882884007025	catalytic site [active]
882884007026	putative proline-specific permease; Provisional; Region: proY; PRK10580
882884007027	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
882884007028	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
882884007029	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
882884007030	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
882884007031	putative active site [active]
882884007032	heme pocket [chemical binding]; other site
882884007033	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884007034	dimer interface [polypeptide binding]; other site
882884007035	phosphorylation site [posttranslational modification]
882884007036	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884007037	ATP binding site [chemical binding]; other site
882884007038	Mg2+ binding site [ion binding]; other site
882884007039	G-X-G motif; other site
882884007040	transcriptional regulator PhoB; Provisional; Region: PRK10161
882884007041	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884007042	active site
882884007043	phosphorylation site [posttranslational modification]
882884007044	intermolecular recognition site; other site
882884007045	dimerization interface [polypeptide binding]; other site
882884007046	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884007047	DNA binding site [nucleotide binding]
882884007048	exonuclease subunit SbcD; Provisional; Region: PRK10966
882884007049	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
882884007050	active site
882884007051	metal binding site [ion binding]; metal-binding site
882884007052	DNA binding site [nucleotide binding]
882884007053	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
882884007054	exonuclease subunit SbcC; Provisional; Region: PRK10246
882884007055	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884007056	Walker A/P-loop; other site
882884007057	ATP binding site [chemical binding]; other site
882884007058	Q-loop/lid; other site
882884007059	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884007060	ABC transporter signature motif; other site
882884007061	Walker B; other site
882884007062	D-loop; other site
882884007063	H-loop/switch region; other site
882884007064	MFS transport protein AraJ; Provisional; Region: PRK10091
882884007065	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884007066	putative substrate translocation pore; other site
882884007067	fructokinase; Reviewed; Region: PRK09557
882884007068	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
882884007069	nucleotide binding site [chemical binding]; other site
882884007070	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
882884007071	hypothetical protein; Provisional; Region: PRK10579
882884007072	hypothetical protein; Provisional; Region: PRK10481
882884007073	hypothetical protein; Provisional; Region: PRK10380
882884007074	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
882884007075	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
882884007076	ADP binding site [chemical binding]; other site
882884007077	magnesium binding site [ion binding]; other site
882884007078	putative shikimate binding site; other site
882884007079	hypothetical protein; Validated; Region: PRK00124
882884007080	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
882884007081	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
882884007082	hypothetical protein; Provisional; Region: PRK11505
882884007083	psiF repeat; Region: PsiF_repeat; pfam07769
882884007084	psiF repeat; Region: PsiF_repeat; pfam07769
882884007085	anti-RssB factor; Provisional; Region: PRK10244
882884007086	drug efflux system protein MdtG; Provisional; Region: PRK09874
882884007087	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884007088	putative substrate translocation pore; other site
882884007089	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
882884007090	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
882884007091	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
882884007092	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
882884007093	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
882884007094	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
882884007095	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
882884007096	microcin B17 transporter; Reviewed; Region: PRK11098
882884007097	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
882884007098	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
882884007099	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
882884007100	dimer interface [polypeptide binding]; other site
882884007101	active site
882884007102	Schiff base residues; other site
882884007103	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
882884007104	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
882884007105	acyl-activating enzyme (AAE) consensus motif; other site
882884007106	AMP binding site [chemical binding]; other site
882884007107	active site
882884007108	CoA binding site [chemical binding]; other site
882884007109	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
882884007110	2-methylcitrate dehydratase; Region: prpD; TIGR02330
882884007111	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
882884007112	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
882884007113	dimer interface [polypeptide binding]; other site
882884007114	active site
882884007115	citrylCoA binding site [chemical binding]; other site
882884007116	oxalacetate/citrate binding site [chemical binding]; other site
882884007117	coenzyme A binding site [chemical binding]; other site
882884007118	catalytic triad [active]
882884007119	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
882884007120	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
882884007121	tetramer interface [polypeptide binding]; other site
882884007122	active site
882884007123	Mg2+/Mn2+ binding site [ion binding]; other site
882884007124	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
882884007125	Propionate catabolism activator; Region: PrpR_N; pfam06506
882884007126	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884007127	Walker A motif; other site
882884007128	ATP binding site [chemical binding]; other site
882884007129	Walker B motif; other site
882884007130	arginine finger; other site
882884007131	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
882884007132	hypothetical protein; Provisional; Region: PRK09929
882884007133	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
882884007134	Protein of unknown function (DUF2474); Region: DUF2474; pfam10617
882884007135	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
882884007136	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
882884007137	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
882884007138	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
882884007139	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
882884007140	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
882884007141	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
882884007142	VRR-NUC domain; Region: VRR_NUC; pfam08774
882884007143	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
882884007144	DNA methylase; Region: N6_N4_Mtase; cl17433
882884007145	DNA methylase; Region: N6_N4_Mtase; pfam01555
882884007146	putative sialic acid transporter; Region: 2A0112; TIGR00891
882884007147	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884007148	putative substrate translocation pore; other site
882884007149	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884007150	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884007151	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
882884007152	putative dimerization interface [polypeptide binding]; other site
882884007153	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
882884007154	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
882884007155	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
882884007156	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
882884007157	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
882884007158	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
882884007159	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
882884007160	active site
882884007161	Uncharacterized conserved protein [Function unknown]; Region: COG3777
882884007162	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
882884007163	active site 2 [active]
882884007164	active site 1 [active]
882884007165	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
882884007166	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
882884007167	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
882884007168	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
882884007169	Ligand binding site [chemical binding]; other site
882884007170	Electron transfer flavoprotein domain; Region: ETF; pfam01012
882884007171	Integrase core domain; Region: rve; pfam00665
882884007172	Integrase core domain; Region: rve_3; cl15866
882884007173	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884007174	Transposase; Region: HTH_Tnp_1; cl17663
882884007175	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
882884007176	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
882884007177	Integrase core domain; Region: rve; pfam00665
882884007178	Integrase core domain; Region: rve_3; cl15866
882884007179	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
882884007180	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
882884007181	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
882884007182	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
882884007183	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
882884007184	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
882884007185	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
882884007186	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
882884007187	Peptidase family M23; Region: Peptidase_M23; pfam01551
882884007188	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
882884007189	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
882884007190	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
882884007191	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
882884007192	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
882884007193	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
882884007194	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
882884007195	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
882884007196	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
882884007197	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
882884007198	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
882884007199	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
882884007200	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
882884007201	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
882884007202	S-type Pyocin; Region: Pyocin_S; pfam06958
882884007203	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
882884007204	active site
882884007205	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
882884007206	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
882884007207	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
882884007208	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
882884007209	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
882884007210	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
882884007211	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
882884007212	TPR repeat; Region: TPR_11; pfam13414
882884007213	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
882884007214	binding surface
882884007215	TPR motif; other site
882884007216	Tetratricopeptide repeat; Region: TPR_12; pfam13424
882884007217	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
882884007218	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
882884007219	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
882884007220	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
882884007221	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
882884007222	Integrase core domain; Region: rve; pfam00665
882884007223	Integrase core domain; Region: rve_3; pfam13683
882884007224	PAAR motif; Region: PAAR_motif; pfam05488
882884007225	Peptidase family M23; Region: Peptidase_M23; pfam01551
882884007226	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
882884007227	catalytic residue [active]
882884007228	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
882884007229	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
882884007230	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
882884007231	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
882884007232	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
882884007233	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
882884007234	Clp amino terminal domain; Region: Clp_N; pfam02861
882884007235	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884007236	Walker A motif; other site
882884007237	ATP binding site [chemical binding]; other site
882884007238	Walker B motif; other site
882884007239	arginine finger; other site
882884007240	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884007241	Walker A motif; other site
882884007242	ATP binding site [chemical binding]; other site
882884007243	Walker B motif; other site
882884007244	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
882884007245	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
882884007246	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
882884007247	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
882884007248	ligand binding site [chemical binding]; other site
882884007249	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
882884007250	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
882884007251	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
882884007252	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
882884007253	Protein of unknown function (DUF877); Region: DUF877; pfam05943
882884007254	Protein of unknown function (DUF770); Region: DUF770; pfam05591
882884007255	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
882884007256	Integrase core domain; Region: rve; pfam00665
882884007257	Integrase core domain; Region: rve_3; pfam13683
882884007258	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
882884007259	DNA-binding interface [nucleotide binding]; DNA binding site
882884007260	Winged helix-turn helix; Region: HTH_29; pfam13551
882884007261	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
882884007262	Head binding; Region: Head_binding; pfam09008
882884007263	head assembly protein; Region: PHA00771
882884007264	Protein of unknown function (DUF812); Region: DUF812; pfam05667
882884007265	Phage stabilisation protein; Region: Phage_stabilise; pfam11134
882884007266	P22 tail accessory factor; Region: P22_Tail-4; pfam11650
882884007267	coat protein; Region: PHA01511
882884007268	P22 coat protein - gene protein 5; Region: P22_CoatProtein; pfam11651
882884007269	Bacteriophage, scaffolding protein; Region: Phage-scaffold; pfam09306
882884007270	Terminase-like family; Region: Terminase_6; pfam03237
882884007271	Bacteriophage terminase large (ATPase) subunit and inactivated derivatives [General function prediction only]; Region: COG5565
882884007272	hypothetical protein; Region: PHA00781
882884007273	Protein of unknown function (DUF2560); Region: DUF2560; pfam10834
882884007274	T5orf172 domain; Region: T5orf172; pfam10544
882884007275	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
882884007276	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
882884007277	catalytic residues [active]
882884007278	phage holin, lambda family; Region: holin_lambda; TIGR01594
882884007279	Antitermination protein; Region: Antiterm; pfam03589
882884007280	Antitermination protein; Region: Antiterm; pfam03589
882884007281	hypothetical protein; Provisional; Region: PRK09741
882884007282	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
882884007283	phage replicative helicase, DnaB family, HK022 subfamily; Region: phage_DnaB; TIGR03600
882884007284	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
882884007285	Walker A motif; other site
882884007286	ATP binding site [chemical binding]; other site
882884007287	Walker B motif; other site
882884007288	Protein of unknown function (DUF2740); Region: DUF2740; pfam10872
882884007289	Bacteriophage CII protein; Region: Phage_CII; pfam05269
882884007290	Helix-turn-helix domain; Region: HTH_17; pfam12728
882884007291	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884007292	non-specific DNA binding site [nucleotide binding]; other site
882884007293	salt bridge; other site
882884007294	Predicted transcriptional regulator [Transcription]; Region: COG2932
882884007295	sequence-specific DNA binding site [nucleotide binding]; other site
882884007296	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
882884007297	Catalytic site [active]
882884007298	P63C domain; Region: P63C; pfam10546
882884007299	hypothetical protein; Provisional; Region: PRK09946
882884007300	hypothetical protein; Provisional; Region: PRK09946
882884007301	Bacteriophage lambda Kil protein; Region: Lambda_Kil; pfam06301
882884007302	Rad52/22 family double-strand break repair protein; Region: Rad52_Rad22; cl01936
882884007303	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
882884007304	Protein of unknown function (DUF2856); Region: DUF2856; pfam11043
882884007305	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
882884007306	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
882884007307	active site
882884007308	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
882884007309	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
882884007310	Int/Topo IB signature motif; other site
882884007311	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
882884007312	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
882884007313	putative catalytic cysteine [active]
882884007314	gamma-glutamyl kinase; Provisional; Region: PRK05429
882884007315	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
882884007316	nucleotide binding site [chemical binding]; other site
882884007317	homotetrameric interface [polypeptide binding]; other site
882884007318	putative phosphate binding site [ion binding]; other site
882884007319	putative allosteric binding site; other site
882884007320	PUA domain; Region: PUA; pfam01472
882884007321	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
882884007322	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
882884007323	trimer interface [polypeptide binding]; other site
882884007324	eyelet of channel; other site
882884007325	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
882884007326	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
882884007327	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
882884007328	active site
882884007329	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
882884007330	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
882884007331	metal binding site [ion binding]; metal-binding site
882884007332	dimer interface [polypeptide binding]; other site
882884007333	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
882884007334	active site
882884007335	DNA polymerase IV; Validated; Region: PRK02406
882884007336	DNA binding site [nucleotide binding]
882884007337	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
882884007338	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
882884007339	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
882884007340	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
882884007341	putative active site [active]
882884007342	putative dimer interface [polypeptide binding]; other site
882884007343	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
882884007344	dimer interface [polypeptide binding]; other site
882884007345	active site
882884007346	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
882884007347	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
882884007348	active site
882884007349	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
882884007350	C-N hydrolase family amidase; Provisional; Region: PRK10438
882884007351	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
882884007352	putative active site [active]
882884007353	catalytic triad [active]
882884007354	dimer interface [polypeptide binding]; other site
882884007355	multimer interface [polypeptide binding]; other site
882884007356	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
882884007357	dimer interface [polypeptide binding]; other site
882884007358	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
882884007359	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
882884007360	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
882884007361	ImpA domain protein; Region: DUF3702; pfam12486
882884007362	This entry represents the putative helicase A859L; Region: T5orf172; smart00974
882884007363	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
882884007364	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
882884007365	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
882884007366	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
882884007367	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
882884007368	Protein of unknown function (DUF805); Region: DUF805; cl01224
882884007369	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
882884007370	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
882884007371	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
882884007372	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
882884007373	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
882884007374	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
882884007375	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
882884007376	Uncharacterized conserved protein [Function unknown]; Region: COG1262
882884007377	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
882884007378	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
882884007379	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
882884007380	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
882884007381	Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106
882884007382	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
882884007383	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884007384	Walker A motif; other site
882884007385	ATP binding site [chemical binding]; other site
882884007386	Walker B motif; other site
882884007387	arginine finger; other site
882884007388	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884007389	Walker A motif; other site
882884007390	ATP binding site [chemical binding]; other site
882884007391	Walker B motif; other site
882884007392	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
882884007393	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
882884007394	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
882884007395	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
882884007396	ligand binding site [chemical binding]; other site
882884007397	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
882884007398	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
882884007399	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
882884007400	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
882884007401	Protein of unknown function (DUF877); Region: DUF877; pfam05943
882884007402	Protein of unknown function (DUF770); Region: DUF770; pfam05591
882884007403	Protein of unknown function (DUF2913); Region: DUF2913; pfam11140
882884007404	Methyltransferase domain; Region: Methyltransf_27; pfam13708
882884007405	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
882884007406	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
882884007407	active site
882884007408	catalytic site [active]
882884007409	substrate binding site [chemical binding]; other site
882884007410	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
882884007411	RNA/DNA hybrid binding site [nucleotide binding]; other site
882884007412	active site
882884007413	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884007414	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
882884007415	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
882884007416	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
882884007417	N-acetyl-D-glucosamine binding site [chemical binding]; other site
882884007418	catalytic residue [active]
882884007419	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
882884007420	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
882884007421	hypothetical protein; Provisional; Region: PRK05421
882884007422	putative catalytic site [active]
882884007423	putative metal binding site [ion binding]; other site
882884007424	putative phosphate binding site [ion binding]; other site
882884007425	putative catalytic site [active]
882884007426	putative phosphate binding site [ion binding]; other site
882884007427	putative metal binding site [ion binding]; other site
882884007428	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884007429	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884007430	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
882884007431	putative effector binding pocket; other site
882884007432	dimerization interface [polypeptide binding]; other site
882884007433	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
882884007434	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884007435	active site
882884007436	motif I; other site
882884007437	motif II; other site
882884007438	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
882884007439	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
882884007440	Walker A/P-loop; other site
882884007441	ATP binding site [chemical binding]; other site
882884007442	Q-loop/lid; other site
882884007443	ABC transporter signature motif; other site
882884007444	Walker B; other site
882884007445	D-loop; other site
882884007446	H-loop/switch region; other site
882884007447	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
882884007448	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884007449	dimer interface [polypeptide binding]; other site
882884007450	conserved gate region; other site
882884007451	ABC-ATPase subunit interface; other site
882884007452	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
882884007453	lipoprotein, YaeC family; Region: TIGR00363
882884007454	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
882884007455	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
882884007456	homodimer interaction site [polypeptide binding]; other site
882884007457	cofactor binding site; other site
882884007458	prolyl-tRNA synthetase; Provisional; Region: PRK09194
882884007459	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
882884007460	dimer interface [polypeptide binding]; other site
882884007461	motif 1; other site
882884007462	active site
882884007463	motif 2; other site
882884007464	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
882884007465	putative deacylase active site [active]
882884007466	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
882884007467	active site
882884007468	motif 3; other site
882884007469	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
882884007470	anticodon binding site; other site
882884007471	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
882884007472	NlpE N-terminal domain; Region: NlpE; pfam04170
882884007473	hypothetical protein; Provisional; Region: PRK09256
882884007474	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
882884007475	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
882884007476	hypothetical protein; Provisional; Region: PRK04964
882884007477	Rho-binding antiterminator; Provisional; Region: PRK11625
882884007478	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
882884007479	TilS substrate binding domain; Region: TilS; pfam09179
882884007480	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
882884007481	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
882884007482	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
882884007483	putative metal binding site [ion binding]; other site
882884007484	lysine decarboxylase LdcC; Provisional; Region: PRK15399
882884007485	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
882884007486	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
882884007487	homodimer interface [polypeptide binding]; other site
882884007488	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884007489	catalytic residue [active]
882884007490	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
882884007491	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
882884007492	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
882884007493	putative sugar binding site [chemical binding]; other site
882884007494	catalytic residues [active]
882884007495	PKD domain; Region: PKD; pfam00801
882884007496	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
882884007497	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
882884007498	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
882884007499	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
882884007500	putative active site [active]
882884007501	putative PHP Thumb interface [polypeptide binding]; other site
882884007502	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
882884007503	generic binding surface II; other site
882884007504	generic binding surface I; other site
882884007505	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
882884007506	RNA/DNA hybrid binding site [nucleotide binding]; other site
882884007507	active site
882884007508	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
882884007509	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
882884007510	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
882884007511	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
882884007512	active site
882884007513	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
882884007514	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
882884007515	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
882884007516	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
882884007517	trimer interface [polypeptide binding]; other site
882884007518	active site
882884007519	UDP-GlcNAc binding site [chemical binding]; other site
882884007520	lipid binding site [chemical binding]; lipid-binding site
882884007521	periplasmic chaperone; Provisional; Region: PRK10780
882884007522	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
882884007523	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
882884007524	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
882884007525	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
882884007526	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
882884007527	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
882884007528	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
882884007529	Surface antigen; Region: Bac_surface_Ag; pfam01103
882884007530	zinc metallopeptidase RseP; Provisional; Region: PRK10779
882884007531	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
882884007532	active site
882884007533	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
882884007534	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
882884007535	protein binding site [polypeptide binding]; other site
882884007536	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
882884007537	putative substrate binding region [chemical binding]; other site
882884007538	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
882884007539	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
882884007540	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
882884007541	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
882884007542	catalytic residue [active]
882884007543	putative FPP diphosphate  binding site; other site
882884007544	putative FPP binding hydrophobic cleft; other site
882884007545	dimer interface [polypeptide binding]; other site
882884007546	putative IPP diphosphate binding site; other site
882884007547	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
882884007548	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
882884007549	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
882884007550	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
882884007551	ribosome recycling factor; Reviewed; Region: frr; PRK00083
882884007552	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
882884007553	hinge region; other site
882884007554	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
882884007555	putative nucleotide binding site [chemical binding]; other site
882884007556	uridine monophosphate binding site [chemical binding]; other site
882884007557	homohexameric interface [polypeptide binding]; other site
882884007558	elongation factor Ts; Provisional; Region: tsf; PRK09377
882884007559	UBA/TS-N domain; Region: UBA; pfam00627
882884007560	Elongation factor TS; Region: EF_TS; pfam00889
882884007561	Elongation factor TS; Region: EF_TS; pfam00889
882884007562	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
882884007563	rRNA interaction site [nucleotide binding]; other site
882884007564	S8 interaction site; other site
882884007565	putative laminin-1 binding site; other site
882884007566	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
882884007567	active site
882884007568	PII uridylyl-transferase; Provisional; Region: PRK05007
882884007569	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
882884007570	metal binding triad; other site
882884007571	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
882884007572	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
882884007573	Zn2+ binding site [ion binding]; other site
882884007574	Mg2+ binding site [ion binding]; other site
882884007575	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
882884007576	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
882884007577	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
882884007578	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
882884007579	trimer interface [polypeptide binding]; other site
882884007580	active site
882884007581	substrate binding site [chemical binding]; other site
882884007582	CoA binding site [chemical binding]; other site
882884007583	shikimate transporter; Provisional; Region: PRK09952
882884007584	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884007585	putative substrate translocation pore; other site
882884007586	hypothetical protein; Provisional; Region: PRK13677
882884007587	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
882884007588	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
882884007589	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
882884007590	serine endoprotease; Provisional; Region: PRK10942
882884007591	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
882884007592	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
882884007593	protein binding site [polypeptide binding]; other site
882884007594	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
882884007595	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
882884007596	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
882884007597	Zn2+ binding site [ion binding]; other site
882884007598	Mg2+ binding site [ion binding]; other site
882884007599	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
882884007600	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
882884007601	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
882884007602	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
882884007603	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
882884007604	cobalamin binding residues [chemical binding]; other site
882884007605	putative BtuC binding residues; other site
882884007606	dimer interface [polypeptide binding]; other site
882884007607	hypothetical protein; Provisional; Region: PRK10578
882884007608	UPF0126 domain; Region: UPF0126; pfam03458
882884007609	UPF0126 domain; Region: UPF0126; pfam03458
882884007610	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
882884007611	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
882884007612	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
882884007613	Cl- selectivity filter; other site
882884007614	Cl- binding residues [ion binding]; other site
882884007615	pore gating glutamate residue; other site
882884007616	dimer interface [polypeptide binding]; other site
882884007617	H+/Cl- coupling transport residue; other site
882884007618	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
882884007619	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
882884007620	inhibitor-cofactor binding pocket; inhibition site
882884007621	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884007622	catalytic residue [active]
882884007623	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
882884007624	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
882884007625	ABC-ATPase subunit  interface; other site
882884007626	dimer interface [polypeptide binding]; other site
882884007627	putative PBP binding regions; other site
882884007628	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
882884007629	ABC-ATPase subunit  interface; other site
882884007630	dimer interface [polypeptide binding]; other site
882884007631	putative PBP binding regions; other site
882884007632	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
882884007633	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
882884007634	siderophore binding site; other site
882884007635	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
882884007636	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
882884007637	Walker A/P-loop; other site
882884007638	ATP binding site [chemical binding]; other site
882884007639	Q-loop/lid; other site
882884007640	ABC transporter signature motif; other site
882884007641	Walker B; other site
882884007642	D-loop; other site
882884007643	H-loop/switch region; other site
882884007644	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
882884007645	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
882884007646	N-terminal plug; other site
882884007647	ligand-binding site [chemical binding]; other site
882884007648	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
882884007649	Transglycosylase; Region: Transgly; pfam00912
882884007650	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
882884007651	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
882884007652	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884007653	ATP binding site [chemical binding]; other site
882884007654	putative Mg++ binding site [ion binding]; other site
882884007655	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884007656	nucleotide binding region [chemical binding]; other site
882884007657	ATP-binding site [chemical binding]; other site
882884007658	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
882884007659	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
882884007660	2'-5' RNA ligase; Provisional; Region: PRK15124
882884007661	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
882884007662	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
882884007663	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
882884007664	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
882884007665	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
882884007666	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
882884007667	active site
882884007668	nucleotide binding site [chemical binding]; other site
882884007669	HIGH motif; other site
882884007670	KMSKS motif; other site
882884007671	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
882884007672	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
882884007673	active site
882884007674	NTP binding site [chemical binding]; other site
882884007675	metal binding triad [ion binding]; metal-binding site
882884007676	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
882884007677	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
882884007678	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
882884007679	catalytic center binding site [active]
882884007680	ATP binding site [chemical binding]; other site
882884007681	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
882884007682	oligomerization interface [polypeptide binding]; other site
882884007683	active site
882884007684	metal binding site [ion binding]; metal-binding site
882884007685	pantoate--beta-alanine ligase; Region: panC; TIGR00018
882884007686	Pantoate-beta-alanine ligase; Region: PanC; cd00560
882884007687	active site
882884007688	ATP-binding site [chemical binding]; other site
882884007689	pantoate-binding site; other site
882884007690	HXXH motif; other site
882884007691	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
882884007692	tetramerization interface [polypeptide binding]; other site
882884007693	active site
882884007694	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
882884007695	putative active site [active]
882884007696	putative metal binding site [ion binding]; other site
882884007697	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
882884007698	active pocket/dimerization site; other site
882884007699	active site
882884007700	phosphorylation site [posttranslational modification]
882884007701	inner membrane transport permease; Provisional; Region: PRK15066
882884007702	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
882884007703	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
882884007704	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
882884007705	Walker A/P-loop; other site
882884007706	ATP binding site [chemical binding]; other site
882884007707	Q-loop/lid; other site
882884007708	ABC transporter signature motif; other site
882884007709	Walker B; other site
882884007710	D-loop; other site
882884007711	H-loop/switch region; other site
882884007712	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
882884007713	active site clefts [active]
882884007714	zinc binding site [ion binding]; other site
882884007715	dimer interface [polypeptide binding]; other site
882884007716	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
882884007717	active site
882884007718	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
882884007719	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
882884007720	Trp docking motif [polypeptide binding]; other site
882884007721	putative active site [active]
882884007722	multicopper oxidase; Provisional; Region: PRK10965
882884007723	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
882884007724	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
882884007725	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
882884007726	spermidine synthase; Provisional; Region: PRK00811
882884007727	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884007728	S-adenosylmethionine binding site [chemical binding]; other site
882884007729	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
882884007730	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
882884007731	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
882884007732	active site
882884007733	substrate binding site [chemical binding]; other site
882884007734	trimer interface [polypeptide binding]; other site
882884007735	CoA binding site [chemical binding]; other site
882884007736	galactoside permease; Reviewed; Region: lacY; PRK09528
882884007737	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884007738	putative substrate translocation pore; other site
882884007739	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
882884007740	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
882884007741	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
882884007742	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
882884007743	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
882884007744	lac repressor; Reviewed; Region: lacI; PRK09526
882884007745	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884007746	DNA binding site [nucleotide binding]
882884007747	domain linker motif; other site
882884007748	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
882884007749	ligand binding site [chemical binding]; other site
882884007750	dimerization interface (open form) [polypeptide binding]; other site
882884007751	dimerization interface (closed form) [polypeptide binding]; other site
882884007752	hypothetical protein; Provisional; Region: PRK05248
882884007753	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
882884007754	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
882884007755	substrate binding site [chemical binding]; other site
882884007756	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
882884007757	substrate binding site [chemical binding]; other site
882884007758	ligand binding site [chemical binding]; other site
882884007759	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
882884007760	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
882884007761	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
882884007762	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
882884007763	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884007764	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
882884007765	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
882884007766	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
882884007767	E3 interaction surface; other site
882884007768	lipoyl attachment site [posttranslational modification]; other site
882884007769	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
882884007770	E3 interaction surface; other site
882884007771	lipoyl attachment site [posttranslational modification]; other site
882884007772	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
882884007773	E3 interaction surface; other site
882884007774	lipoyl attachment site [posttranslational modification]; other site
882884007775	e3 binding domain; Region: E3_binding; pfam02817
882884007776	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
882884007777	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
882884007778	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
882884007779	dimer interface [polypeptide binding]; other site
882884007780	TPP-binding site [chemical binding]; other site
882884007781	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
882884007782	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884007783	DNA-binding site [nucleotide binding]; DNA binding site
882884007784	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
882884007785	aromatic amino acid transporter; Provisional; Region: PRK10238
882884007786	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
882884007787	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884007788	putative substrate translocation pore; other site
882884007789	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
882884007790	active site
882884007791	regulatory protein AmpE; Provisional; Region: PRK10987
882884007792	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
882884007793	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
882884007794	amidase catalytic site [active]
882884007795	substrate binding site [chemical binding]; other site
882884007796	Zn binding residues [ion binding]; other site
882884007797	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
882884007798	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
882884007799	dimerization interface [polypeptide binding]; other site
882884007800	active site
882884007801	putative major pilin subunit; Provisional; Region: PRK10574
882884007802	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
882884007803	Pilin (bacterial filament); Region: Pilin; pfam00114
882884007804	hypothetical protein; Provisional; Region: PRK10436
882884007805	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
882884007806	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
882884007807	Walker A motif; other site
882884007808	ATP binding site [chemical binding]; other site
882884007809	Walker B motif; other site
882884007810	type IV pilin biogenesis protein; Provisional; Region: PRK10573
882884007811	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
882884007812	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
882884007813	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
882884007814	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
882884007815	active site
882884007816	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
882884007817	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
882884007818	CoA-binding site [chemical binding]; other site
882884007819	ATP-binding [chemical binding]; other site
882884007820	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
882884007821	DNA gyrase inhibitor; Reviewed; Region: PRK00418
882884007822	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884007823	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
882884007824	active site
882884007825	8-oxo-dGMP binding site [chemical binding]; other site
882884007826	nudix motif; other site
882884007827	metal binding site [ion binding]; metal-binding site
882884007828	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
882884007829	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
882884007830	SEC-C motif; Region: SEC-C; pfam02810
882884007831	SecA regulator SecM; Provisional; Region: PRK02943
882884007832	Glycine zipper; Region: Gly-zipper_Omp; cl17724
882884007833	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
882884007834	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
882884007835	cell division protein FtsZ; Validated; Region: PRK09330
882884007836	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
882884007837	nucleotide binding site [chemical binding]; other site
882884007838	SulA interaction site; other site
882884007839	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
882884007840	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
882884007841	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
882884007842	Cell division protein FtsA; Region: FtsA; pfam14450
882884007843	cell division protein FtsQ; Provisional; Region: PRK10775
882884007844	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
882884007845	Cell division protein FtsQ; Region: FtsQ; pfam03799
882884007846	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
882884007847	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
882884007848	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
882884007849	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
882884007850	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
882884007851	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
882884007852	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
882884007853	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
882884007854	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
882884007855	active site
882884007856	homodimer interface [polypeptide binding]; other site
882884007857	cell division protein FtsW; Provisional; Region: PRK10774
882884007858	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
882884007859	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
882884007860	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
882884007861	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
882884007862	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
882884007863	Mg++ binding site [ion binding]; other site
882884007864	putative catalytic motif [active]
882884007865	putative substrate binding site [chemical binding]; other site
882884007866	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
882884007867	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
882884007868	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
882884007869	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
882884007870	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
882884007871	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
882884007872	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
882884007873	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
882884007874	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
882884007875	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
882884007876	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
882884007877	cell division protein FtsL; Provisional; Region: PRK10772
882884007878	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
882884007879	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
882884007880	mraZ protein; Region: TIGR00242
882884007881	MraZ protein; Region: MraZ; pfam02381
882884007882	MraZ protein; Region: MraZ; pfam02381
882884007883	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
882884007884	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884007885	DNA binding site [nucleotide binding]
882884007886	domain linker motif; other site
882884007887	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
882884007888	dimerization interface [polypeptide binding]; other site
882884007889	ligand binding site [chemical binding]; other site
882884007890	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
882884007891	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
882884007892	putative valine binding site [chemical binding]; other site
882884007893	dimer interface [polypeptide binding]; other site
882884007894	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
882884007895	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
882884007896	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
882884007897	PYR/PP interface [polypeptide binding]; other site
882884007898	dimer interface [polypeptide binding]; other site
882884007899	TPP binding site [chemical binding]; other site
882884007900	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
882884007901	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
882884007902	TPP-binding site [chemical binding]; other site
882884007903	dimer interface [polypeptide binding]; other site
882884007904	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
882884007905	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884007906	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
882884007907	putative substrate binding pocket [chemical binding]; other site
882884007908	putative dimerization interface [polypeptide binding]; other site
882884007909	leucine operon leader
882884007910	2-isopropylmalate synthase; Validated; Region: PRK00915
882884007911	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
882884007912	active site
882884007913	catalytic residues [active]
882884007914	metal binding site [ion binding]; metal-binding site
882884007915	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
882884007916	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
882884007917	tartrate dehydrogenase; Region: TTC; TIGR02089
882884007918	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
882884007919	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
882884007920	substrate binding site [chemical binding]; other site
882884007921	ligand binding site [chemical binding]; other site
882884007922	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
882884007923	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
882884007924	substrate binding site [chemical binding]; other site
882884007925	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884007926	sugar efflux transporter; Region: 2A0120; TIGR00899
882884007927	putative substrate translocation pore; other site
882884007928	transcriptional regulator SgrR; Provisional; Region: PRK13626
882884007929	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
882884007930	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
882884007931	TPP riboswitch (THI element)
882884007932	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
882884007933	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
882884007934	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
882884007935	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884007936	dimer interface [polypeptide binding]; other site
882884007937	conserved gate region; other site
882884007938	putative PBP binding loops; other site
882884007939	ABC-ATPase subunit interface; other site
882884007940	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884007941	dimer interface [polypeptide binding]; other site
882884007942	conserved gate region; other site
882884007943	putative PBP binding loops; other site
882884007944	ABC-ATPase subunit interface; other site
882884007945	thiamine ABC transporter, ATP-binding protein; Region: thiQ; TIGR01277
882884007946	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
882884007947	Walker A/P-loop; other site
882884007948	ATP binding site [chemical binding]; other site
882884007949	Q-loop/lid; other site
882884007950	ABC transporter signature motif; other site
882884007951	Walker B; other site
882884007952	D-loop; other site
882884007953	H-loop/switch region; other site
882884007954	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
882884007955	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
882884007956	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
882884007957	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
882884007958	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884007959	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884007960	ribulokinase; Provisional; Region: PRK04123
882884007961	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
882884007962	N- and C-terminal domain interface [polypeptide binding]; other site
882884007963	active site
882884007964	MgATP binding site [chemical binding]; other site
882884007965	catalytic site [active]
882884007966	metal binding site [ion binding]; metal-binding site
882884007967	carbohydrate binding site [chemical binding]; other site
882884007968	homodimer interface [polypeptide binding]; other site
882884007969	L-arabinose isomerase; Provisional; Region: PRK02929
882884007970	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
882884007971	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
882884007972	trimer interface [polypeptide binding]; other site
882884007973	putative substrate binding site [chemical binding]; other site
882884007974	putative metal binding site [ion binding]; other site
882884007975	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
882884007976	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
882884007977	intersubunit interface [polypeptide binding]; other site
882884007978	active site
882884007979	Zn2+ binding site [ion binding]; other site
882884007980	DNA polymerase II; Reviewed; Region: PRK05762
882884007981	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
882884007982	active site
882884007983	catalytic site [active]
882884007984	substrate binding site [chemical binding]; other site
882884007985	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
882884007986	active site
882884007987	metal-binding site
882884007988	ATP-dependent helicase HepA; Validated; Region: PRK04914
882884007989	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884007990	ATP binding site [chemical binding]; other site
882884007991	putative Mg++ binding site [ion binding]; other site
882884007992	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884007993	nucleotide binding region [chemical binding]; other site
882884007994	ATP-binding site [chemical binding]; other site
882884007995	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
882884007996	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
882884007997	active site
882884007998	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
882884007999	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
882884008000	putative metal binding site [ion binding]; other site
882884008001	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
882884008002	HSP70 interaction site [polypeptide binding]; other site
882884008003	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
882884008004	OstA-like protein; Region: OstA; pfam03968
882884008005	Organic solvent tolerance protein; Region: OstA_C; pfam04453
882884008006	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
882884008007	SurA N-terminal domain; Region: SurA_N; pfam09312
882884008008	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
882884008009	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
882884008010	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
882884008011	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
882884008012	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
882884008013	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
882884008014	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
882884008015	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
882884008016	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
882884008017	active site
882884008018	metal binding site [ion binding]; metal-binding site
882884008019	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
882884008020	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
882884008021	folate binding site [chemical binding]; other site
882884008022	NADP+ binding site [chemical binding]; other site
882884008023	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
882884008024	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
882884008025	TrkA-N domain; Region: TrkA_N; pfam02254
882884008026	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
882884008027	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
882884008028	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884008029	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
882884008030	putative substrate translocation pore; other site
882884008031	ferredoxin-like protein FixX; Provisional; Region: PRK15449
882884008032	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
882884008033	putative oxidoreductase FixC; Provisional; Region: PRK10157
882884008034	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
882884008035	Electron transfer flavoprotein domain; Region: ETF; smart00893
882884008036	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
882884008037	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
882884008038	Ligand binding site [chemical binding]; other site
882884008039	Electron transfer flavoprotein domain; Region: ETF; pfam01012
882884008040	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
882884008041	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
882884008042	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
882884008043	active site
882884008044	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
882884008045	CoA-transferase family III; Region: CoA_transf_3; pfam02515
882884008046	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
882884008047	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
882884008048	acyl-activating enzyme (AAE) consensus motif; other site
882884008049	putative AMP binding site [chemical binding]; other site
882884008050	putative active site [active]
882884008051	putative CoA binding site [chemical binding]; other site
882884008052	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
882884008053	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
882884008054	substrate binding site [chemical binding]; other site
882884008055	oxyanion hole (OAH) forming residues; other site
882884008056	trimer interface [polypeptide binding]; other site
882884008057	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884008058	Sulfatase; Region: Sulfatase; cl17466
882884008059	Sulfatase; Region: Sulfatase; cl17466
882884008060	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
882884008061	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
882884008062	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
882884008063	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
882884008064	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
882884008065	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
882884008066	ATP-grasp domain; Region: ATP-grasp_4; cl17255
882884008067	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
882884008068	IMP binding site; other site
882884008069	dimer interface [polypeptide binding]; other site
882884008070	interdomain contacts; other site
882884008071	partial ornithine binding site; other site
882884008072	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
882884008073	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
882884008074	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
882884008075	catalytic site [active]
882884008076	subunit interface [polypeptide binding]; other site
882884008077	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
882884008078	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
882884008079	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
882884008080	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
882884008081	active site
882884008082	tetramer interface [polypeptide binding]; other site
882884008083	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
882884008084	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
882884008085	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
882884008086	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
882884008087	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
882884008088	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
882884008089	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
882884008090	HIGH motif; other site
882884008091	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
882884008092	active site
882884008093	KMSKS motif; other site
882884008094	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
882884008095	tRNA binding surface [nucleotide binding]; other site
882884008096	anticodon binding site; other site
882884008097	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
882884008098	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
882884008099	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
882884008100	active site
882884008101	Riboflavin kinase; Region: Flavokinase; smart00904
882884008102	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
882884008103	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
882884008104	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884008105	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
882884008106	putative dimerization interface [polypeptide binding]; other site
882884008107	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
882884008108	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
882884008109	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
882884008110	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884008111	FeS/SAM binding site; other site
882884008112	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
882884008113	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884008114	Sulfatase; Region: Sulfatase; pfam00884
882884008115	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
882884008116	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
882884008117	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
882884008118	active site
882884008119	metal binding site [ion binding]; metal-binding site
882884008120	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
882884008121	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
882884008122	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
882884008123	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884008124	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884008125	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884008126	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
882884008127	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
882884008128	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
882884008129	catalytic residues [active]
882884008130	fimbrial chaperone BcfG; Provisional; Region: PRK15192
882884008131	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
882884008132	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
882884008133	fimbrial protein BcfF; Provisional; Region: PRK15191
882884008134	fimbrial protein BcfE; Provisional; Region: PRK15190
882884008135	fimbrial protein BcfD; Provisional; Region: PRK15189
882884008136	outer membrane usher protein; Provisional; Region: PRK15193
882884008137	PapC N-terminal domain; Region: PapC_N; pfam13954
882884008138	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
882884008139	PapC C-terminal domain; Region: PapC_C; pfam13953
882884008140	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
882884008141	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
882884008142	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
882884008143	fimbrial protein BcfA; Provisional; Region: PRK15187
882884008144	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
882884008145	Helix-turn-helix domain; Region: HTH_36; pfam13730
882884008146	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
882884008147	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
882884008148	active site
882884008149	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
882884008150	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
882884008151	aromatic chitin/cellulose binding site residues [chemical binding]; other site
882884008152	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
882884008153	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
882884008154	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
882884008155	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
882884008156	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884008157	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884008158	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884008159	dimerization interface [polypeptide binding]; other site
882884008160	chaperone protein DnaJ; Provisional; Region: PRK10767
882884008161	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
882884008162	HSP70 interaction site [polypeptide binding]; other site
882884008163	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
882884008164	substrate binding site [polypeptide binding]; other site
882884008165	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
882884008166	Zn binding sites [ion binding]; other site
882884008167	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
882884008168	dimer interface [polypeptide binding]; other site
882884008169	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
882884008170	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
882884008171	nucleotide binding site [chemical binding]; other site
882884008172	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
882884008173	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
882884008174	catalytic residues [active]
882884008175	catalytic nucleophile [active]
882884008176	hypothetical protein; Provisional; Region: PRK10659
882884008177	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
882884008178	MPT binding site; other site
882884008179	trimer interface [polypeptide binding]; other site
882884008180	Uncharacterized conserved protein [Function unknown]; Region: COG5464
882884008181	transaldolase-like protein; Provisional; Region: PTZ00411
882884008182	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
882884008183	active site
882884008184	dimer interface [polypeptide binding]; other site
882884008185	catalytic residue [active]
882884008186	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
882884008187	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
882884008188	hypothetical protein; Validated; Region: PRK02101
882884008189	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
882884008190	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
882884008191	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884008192	catalytic residue [active]
882884008193	homoserine kinase; Provisional; Region: PRK01212
882884008194	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
882884008195	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
882884008196	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
882884008197	putative catalytic residues [active]
882884008198	putative nucleotide binding site [chemical binding]; other site
882884008199	putative aspartate binding site [chemical binding]; other site
882884008200	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
882884008201	dimer interface [polypeptide binding]; other site
882884008202	putative threonine allosteric regulatory site; other site
882884008203	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
882884008204	putative threonine allosteric regulatory site; other site
882884008205	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
882884008206	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
882884008207	threonine operon leader
882884008208	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
882884008209	putative RNA methyltransferase; Provisional; Region: PRK10433
882884008210	two-component response regulator; Provisional; Region: PRK11173
882884008211	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884008212	active site
882884008213	phosphorylation site [posttranslational modification]
882884008214	intermolecular recognition site; other site
882884008215	dimerization interface [polypeptide binding]; other site
882884008216	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884008217	DNA binding site [nucleotide binding]
882884008218	putative major fimbrial protein SthE; Provisional; Region: PRK15292
882884008219	Inner membrane protein CreD; Region: CreD; cl01844
882884008220	hypothetical protein; Provisional; Region: PRK10756
882884008221	CreA protein; Region: CreA; pfam05981
882884008222	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
882884008223	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884008224	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
882884008225	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
882884008226	catalytic core [active]
882884008227	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
882884008228	Trp operon repressor; Provisional; Region: PRK01381
882884008229	lytic murein transglycosylase; Provisional; Region: PRK11619
882884008230	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
882884008231	N-acetyl-D-glucosamine binding site [chemical binding]; other site
882884008232	catalytic residue [active]
882884008233	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
882884008234	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884008235	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884008236	ABC transporter; Region: ABC_tran_2; pfam12848
882884008237	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884008238	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884008239	non-specific DNA binding site [nucleotide binding]; other site
882884008240	salt bridge; other site
882884008241	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
882884008242	sequence-specific DNA binding site [nucleotide binding]; other site
882884008243	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
882884008244	active site
882884008245	(T/H)XGH motif; other site
882884008246	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
882884008247	DNA repair protein RadA; Region: sms; TIGR00416
882884008248	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
882884008249	Walker A motif/ATP binding site; other site
882884008250	ATP binding site [chemical binding]; other site
882884008251	Walker B motif; other site
882884008252	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
882884008253	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
882884008254	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
882884008255	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884008256	motif II; other site
882884008257	hypothetical protein; Provisional; Region: PRK11246
882884008258	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
882884008259	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
882884008260	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
882884008261	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
882884008262	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
882884008263	phosphopentomutase; Provisional; Region: PRK05362
882884008264	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
882884008265	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
882884008266	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
882884008267	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
882884008268	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
882884008269	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
882884008270	intersubunit interface [polypeptide binding]; other site
882884008271	active site
882884008272	catalytic residue [active]
882884008273	hypothetical protein; Provisional; Region: PRK10977
882884008274	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
882884008275	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
882884008276	active site
882884008277	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
882884008278	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
882884008279	active site
882884008280	nucleophile elbow; other site
882884008281	periplasmic protein; Provisional; Region: PRK10568
882884008282	BON domain; Region: BON; pfam04972
882884008283	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
882884008284	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
882884008285	G1 box; other site
882884008286	putative GEF interaction site [polypeptide binding]; other site
882884008287	GTP/Mg2+ binding site [chemical binding]; other site
882884008288	Switch I region; other site
882884008289	G2 box; other site
882884008290	G3 box; other site
882884008291	Switch II region; other site
882884008292	G4 box; other site
882884008293	G5 box; other site
882884008294	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
882884008295	dUMP phosphatase; Provisional; Region: PRK09449
882884008296	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884008297	motif II; other site
882884008298	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
882884008299	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884008300	Coenzyme A binding pocket [chemical binding]; other site
882884008301	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
882884008302	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
882884008303	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884008304	S-adenosylmethionine binding site [chemical binding]; other site
882884008305	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
882884008306	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
882884008307	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
882884008308	metal binding site [ion binding]; metal-binding site
882884008309	active site
882884008310	I-site; other site
882884008311	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
882884008312	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
882884008313	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
882884008314	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
882884008315	putative deacylase active site [active]
882884008316	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
882884008317	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884008318	DNA binding residues [nucleotide binding]
882884008319	dimerization interface [polypeptide binding]; other site
882884008320	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
882884008321	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884008322	DNA binding residues [nucleotide binding]
882884008323	dimerization interface [polypeptide binding]; other site
882884008324	Uncharacterized conserved protein [Function unknown]; Region: COG2966
882884008325	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
882884008326	hypothetical protein; Provisional; Region: PRK09917
882884008327	primosomal protein DnaI; Provisional; Region: PRK02854
882884008328	DNA replication protein DnaC; Validated; Region: PRK07952
882884008329	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884008330	Walker A motif; other site
882884008331	ATP binding site [chemical binding]; other site
882884008332	Walker B motif; other site
882884008333	phosphoglycerol transferase I; Provisional; Region: PRK03776
882884008334	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
882884008335	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
882884008336	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
882884008337	putative active site [active]
882884008338	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
882884008339	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
882884008340	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
882884008341	dimer interface [polypeptide binding]; other site
882884008342	active site
882884008343	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
882884008344	dimer interface [polypeptide binding]; other site
882884008345	active site
882884008346	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
882884008347	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
882884008348	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
882884008349	active site
882884008350	phosphorylation site [posttranslational modification]
882884008351	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
882884008352	active pocket/dimerization site; other site
882884008353	active site
882884008354	phosphorylation site [posttranslational modification]
882884008355	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
882884008356	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884008357	Walker A motif; other site
882884008358	ATP binding site [chemical binding]; other site
882884008359	Walker B motif; other site
882884008360	arginine finger; other site
882884008361	Transcriptional antiterminator [Transcription]; Region: COG3933
882884008362	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
882884008363	active pocket/dimerization site; other site
882884008364	active site
882884008365	phosphorylation site [posttranslational modification]
882884008366	PRD domain; Region: PRD; pfam00874
882884008367	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
882884008368	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
882884008369	dimer interface [polypeptide binding]; other site
882884008370	ligand binding site [chemical binding]; other site
882884008371	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884008372	dimerization interface [polypeptide binding]; other site
882884008373	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
882884008374	dimer interface [polypeptide binding]; other site
882884008375	putative CheW interface [polypeptide binding]; other site
882884008376	carbon starvation protein A; Provisional; Region: PRK15015
882884008377	Carbon starvation protein CstA; Region: CstA; pfam02554
882884008378	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
882884008379	Uncharacterized small protein [Function unknown]; Region: COG2879
882884008380	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
882884008381	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
882884008382	P-loop, Walker A motif; other site
882884008383	Base recognition motif; other site
882884008384	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
882884008385	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
882884008386	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
882884008387	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884008388	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
882884008389	Protein of unknown function DUF91; Region: DUF91; cl00709
882884008390	Uncharacterized conserved protein [Function unknown]; Region: COG3586
882884008391	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
882884008392	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
882884008393	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
882884008394	NAD(P) binding site [chemical binding]; other site
882884008395	catalytic residues [active]
882884008396	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
882884008397	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884008398	putative substrate translocation pore; other site
882884008399	Predicted membrane protein [Function unknown]; Region: COG2733
882884008400	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
882884008401	Homeodomain-like domain; Region: HTH_23; pfam13384
882884008402	Winged helix-turn helix; Region: HTH_29; pfam13551
882884008403	Homeodomain-like domain; Region: HTH_32; pfam13565
882884008404	Winged helix-turn helix; Region: HTH_33; pfam13592
882884008405	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
882884008406	DDE superfamily endonuclease; Region: DDE_3; pfam13358
882884008407	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
882884008408	Nucleoside recognition; Region: Gate; pfam07670
882884008409	hypothetical protein; Provisional; Region: PRK10519
882884008410	isoaspartyl dipeptidase; Provisional; Region: PRK10657
882884008411	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
882884008412	active site
882884008413	cell density-dependent motility repressor; Provisional; Region: PRK10082
882884008414	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884008415	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
882884008416	dimerization interface [polypeptide binding]; other site
882884008417	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
882884008418	aspartate racemase; Region: asp_race; TIGR00035
882884008419	Protein of unknown function (DUF796); Region: DUF796; cl01226
882884008420	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
882884008421	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
882884008422	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884008423	DNA-binding site [nucleotide binding]; DNA binding site
882884008424	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
882884008425	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
882884008426	Uncharacterized conserved protein [Function unknown]; Region: COG3439
882884008427	Integrase core domain; Region: rve; pfam00665
882884008428	Integrase core domain; Region: rve_2; pfam13333
882884008429	HTH-like domain; Region: HTH_21; pfam13276
882884008430	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
882884008431	Transposase; Region: DEDD_Tnp_IS110; pfam01548
882884008432	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884008433	Transposase; Region: HTH_Tnp_1; cl17663
882884008434	integrase; Provisional; Region: PRK09692
882884008435	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
882884008436	active site
882884008437	Int/Topo IB signature motif; other site
882884008438	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
882884008439	AAA domain; Region: AAA_31; pfam13614
882884008440	P-loop; other site
882884008441	Magnesium ion binding site [ion binding]; other site
882884008442	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
882884008443	Magnesium ion binding site [ion binding]; other site
882884008444	replicative DNA helicase; Region: DnaB; TIGR00665
882884008445	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
882884008446	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
882884008447	Walker A motif; other site
882884008448	ATP binding site [chemical binding]; other site
882884008449	Walker B motif; other site
882884008450	DNA binding loops [nucleotide binding]
882884008451	integrating conjugative element, PFGI_1 class, ParB family protein; Region: ICE_PFGI_1_parB; TIGR03764
882884008452	ParB-like nuclease domain; Region: ParBc; pfam02195
882884008453	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
882884008454	Homeodomain-like domain; Region: HTH_23; pfam13384
882884008455	Winged helix-turn helix; Region: HTH_29; pfam13551
882884008456	Homeodomain-like domain; Region: HTH_32; pfam13565
882884008457	Winged helix-turn helix; Region: HTH_33; pfam13592
882884008458	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
882884008459	DDE superfamily endonuclease; Region: DDE_3; pfam13358
882884008460	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
882884008461	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
882884008462	Autotransporter beta-domain; Region: Autotransporter; pfam03797
882884008463	Fic family protein [Function unknown]; Region: COG3177
882884008464	Fic/DOC family; Region: Fic; pfam02661
882884008465	integrating conjugative element protein, PFL_4669 family; Region: ICE_PFL4669; TIGR03761
882884008466	Protein of unknown function (DUF3158); Region: DUF3158; pfam11358
882884008467	Protein of unknown function (DUF3577); Region: DUF3577; pfam12101
882884008468	conjugative transfer region protein, TIGR03748 family; Region: conj_PilL
882884008469	seryl-tRNA synthetase; Region: serS; TIGR00414
882884008470	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
882884008471	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
882884008472	N-acetyl-D-glucosamine binding site [chemical binding]; other site
882884008473	integrating conjugative element protein, PFL_4695 family; Region: ICE_PFL_4695; TIGR03765
882884008474	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
882884008475	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
882884008476	Domain of unknown function (DUF4400); Region: DUF4400; cl14023
882884008477	Protein of unknwon function (DUF2893); Region: DUF2893; pfam11459
882884008478	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
882884008479	integrative conjugative element protein, RAQPRD family; Region: ICE_RAQPRD; TIGR01690
882884008480	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
882884008481	Protein of unknown function (DUF3262); Region: DUF3262; pfam11660
882884008482	integrating conjugative element membrane protein, PFL_4702 family; Region: conj_TIGR03745
882884008483	conjugative transfer region protein, TIGR03750 family; Region: conj_TIGR03750
882884008484	integrating conjugative element protein, PFL_4703 family; Region: conj_TIGR03746
882884008485	Protein of unknown function (DUF3438); Region: DUF3438; pfam11920
882884008486	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
882884008487	Protein of unknown function (DUF904); Region: DUF904; pfam06005
882884008488	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
882884008489	conjugative transfer ATPase, PFL_4706 family; Region: traC_PFL_4706; TIGR03744
882884008490	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
882884008491	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
882884008492	Walker A motif; other site
882884008493	ATP binding site [chemical binding]; other site
882884008494	Protein of unknown function (DUF796); Region: DUF796; cl01226
882884008495	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
882884008496	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884008497	non-specific DNA binding site [nucleotide binding]; other site
882884008498	salt bridge; other site
882884008499	sequence-specific DNA binding site [nucleotide binding]; other site
882884008500	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
882884008501	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884008502	non-specific DNA binding site [nucleotide binding]; other site
882884008503	salt bridge; other site
882884008504	sequence-specific DNA binding site [nucleotide binding]; other site
882884008505	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
882884008506	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
882884008507	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
882884008508	ligand binding site [chemical binding]; other site
882884008509	flexible hinge region; other site
882884008510	DNA cytosine methylase; Provisional; Region: PRK10458
882884008511	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
882884008512	cofactor binding site; other site
882884008513	DNA binding site [nucleotide binding]
882884008514	substrate interaction site [chemical binding]; other site
882884008515	N-terminal domain of type IIE restriction endonuclease EcoRII and similar proteins; Region: EcoRII_N; cd10016
882884008516	DNA binding site [nucleotide binding]
882884008517	EcoRII C terminal; Region: EcoRII-C; pfam09019
882884008518	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
882884008519	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884008520	FeS/SAM binding site; other site
882884008521	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
882884008522	Predicted permeases [General function prediction only]; Region: COG0730
882884008523	Sulfatase; Region: Sulfatase; cl17466
882884008524	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884008525	galactoside permease; Reviewed; Region: lacY; PRK09528
882884008526	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884008527	putative substrate translocation pore; other site
882884008528	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
882884008529	Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain; Region: NAGLU_N; pfam12971
882884008530	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain; Region: NAGLU; pfam05089
882884008531	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; Region: NAGLU_C; pfam12972
882884008532	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
882884008533	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
882884008534	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cd00413
882884008535	active site
882884008536	catalytic residues [active]
882884008537	TraU protein; Region: TraU; cl06067
882884008538	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
882884008539	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
882884008540	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884008541	S-adenosylmethionine binding site [chemical binding]; other site
882884008542	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
882884008543	active site
882884008544	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
882884008545	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884008546	ATP binding site [chemical binding]; other site
882884008547	Mg2+ binding site [ion binding]; other site
882884008548	G-X-G motif; other site
882884008549	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
882884008550	HNH endonuclease; Region: HNH_2; pfam13391
882884008551	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
882884008552	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
882884008553	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
882884008554	Putative helicase; Region: TraI_2; pfam07514
882884008555	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
882884008556	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
882884008557	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
882884008558	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
882884008559	active site
882884008560	catalytic residues [active]
882884008561	DNA binding site [nucleotide binding]
882884008562	Int/Topo IB signature motif; other site
882884008563	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
882884008564	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
882884008565	putative NAD(P) binding site [chemical binding]; other site
882884008566	putative substrate binding site [chemical binding]; other site
882884008567	catalytic Zn binding site [ion binding]; other site
882884008568	structural Zn binding site [ion binding]; other site
882884008569	dimer interface [polypeptide binding]; other site
882884008570	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
882884008571	ATP-binding site [chemical binding]; other site
882884008572	Gluconate-6-phosphate binding site [chemical binding]; other site
882884008573	Shikimate kinase; Region: SKI; pfam01202
882884008574	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
882884008575	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
882884008576	fructuronate transporter; Provisional; Region: PRK10034; cl15264
882884008577	fructuronate transporter; Provisional; Region: PRK10034; cl15264
882884008578	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
882884008579	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
882884008580	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
882884008581	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
882884008582	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
882884008583	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
882884008584	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
882884008585	multifunctional aminopeptidase A; Provisional; Region: PRK00913
882884008586	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
882884008587	interface (dimer of trimers) [polypeptide binding]; other site
882884008588	Substrate-binding/catalytic site; other site
882884008589	Zn-binding sites [ion binding]; other site
882884008590	DNA polymerase III subunit chi; Validated; Region: PRK05728
882884008591	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
882884008592	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
882884008593	HIGH motif; other site
882884008594	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
882884008595	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
882884008596	active site
882884008597	KMSKS motif; other site
882884008598	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
882884008599	tRNA binding surface [nucleotide binding]; other site
882884008600	anticodon binding site; other site
882884008601	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
882884008602	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884008603	Coenzyme A binding pocket [chemical binding]; other site
882884008604	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
882884008605	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
882884008606	active site
882884008607	dinuclear metal binding site [ion binding]; other site
882884008608	dimerization interface [polypeptide binding]; other site
882884008609	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
882884008610	RNase E inhibitor protein; Provisional; Region: PRK11191
882884008611	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
882884008612	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
882884008613	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
882884008614	Domain of unknown function (DUF386); Region: DUF386; cl01047
882884008615	arginine deiminase; Provisional; Region: PRK01388
882884008616	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
882884008617	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
882884008618	putative substrate binding site [chemical binding]; other site
882884008619	nucleotide binding site [chemical binding]; other site
882884008620	nucleotide binding site [chemical binding]; other site
882884008621	homodimer interface [polypeptide binding]; other site
882884008622	ornithine carbamoyltransferase; Validated; Region: PRK02102
882884008623	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
882884008624	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
882884008625	Predicted membrane protein [Function unknown]; Region: COG1288
882884008626	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
882884008627	Arginine repressor [Transcription]; Region: ArgR; COG1438
882884008628	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
882884008629	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
882884008630	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
882884008631	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
882884008632	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
882884008633	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
882884008634	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
882884008635	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
882884008636	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
882884008637	homotrimer interaction site [polypeptide binding]; other site
882884008638	putative active site [active]
882884008639	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
882884008640	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
882884008641	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
882884008642	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
882884008643	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
882884008644	Soluble P-type ATPase [General function prediction only]; Region: COG4087
882884008645	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
882884008646	trehalose repressor; Provisional; Region: treR; PRK09492
882884008647	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884008648	DNA binding site [nucleotide binding]
882884008649	domain linker motif; other site
882884008650	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
882884008651	dimerization interface [polypeptide binding]; other site
882884008652	ligand binding site [chemical binding]; other site
882884008653	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
882884008654	active site turn [active]
882884008655	phosphorylation site [posttranslational modification]
882884008656	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
882884008657	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl17885
882884008658	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
882884008659	ATP cone domain; Region: ATP-cone; pfam03477
882884008660	Class III ribonucleotide reductase; Region: RNR_III; cd01675
882884008661	effector binding site; other site
882884008662	active site
882884008663	Zn binding site [ion binding]; other site
882884008664	glycine loop; other site
882884008665	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
882884008666	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884008667	FeS/SAM binding site; other site
882884008668	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
882884008669	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
882884008670	Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism]; Region: MtlA; COG4668
882884008671	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; cl11916
882884008672	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
882884008673	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
882884008674	cytochrome b562; Provisional; Region: PRK15058
882884008675	peptidase PmbA; Provisional; Region: PRK11040
882884008676	hypothetical protein; Provisional; Region: PRK05255
882884008677	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
882884008678	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
882884008679	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
882884008680	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
882884008681	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
882884008682	AMP binding site [chemical binding]; other site
882884008683	metal binding site [ion binding]; metal-binding site
882884008684	active site
882884008685	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
882884008686	dimer interface [polypeptide binding]; other site
882884008687	substrate binding site [chemical binding]; other site
882884008688	metal binding sites [ion binding]; metal-binding site
882884008689	Protein of unknown function (DUF796); Region: DUF796; cl01226
882884008690	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
882884008691	putative active site pocket [active]
882884008692	dimerization interface [polypeptide binding]; other site
882884008693	putative catalytic residue [active]
882884008694	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
882884008695	Family of unknown function (DUF490); Region: DUF490; pfam04357
882884008696	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
882884008697	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
882884008698	Surface antigen; Region: Bac_surface_Ag; pfam01103
882884008699	methionine sulfoxide reductase A; Provisional; Region: PRK00058
882884008700	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
882884008701	Domain of unknown function DUF21; Region: DUF21; pfam01595
882884008702	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
882884008703	Transporter associated domain; Region: CorC_HlyC; smart01091
882884008704	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
882884008705	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
882884008706	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
882884008707	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
882884008708	active site
882884008709	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
882884008710	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
882884008711	active site
882884008712	metal binding site [ion binding]; metal-binding site
882884008713	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
882884008714	Predicted transcriptional regulators [Transcription]; Region: COG1733
882884008715	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
882884008716	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
882884008717	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
882884008718	NADP binding site [chemical binding]; other site
882884008719	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
882884008720	EamA-like transporter family; Region: EamA; pfam00892
882884008721	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
882884008722	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
882884008723	Hemerythrin-like domain; Region: Hr-like; cd12108
882884008724	Fe binding site [ion binding]; other site
882884008725	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
882884008726	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
882884008727	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
882884008728	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
882884008729	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
882884008730	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
882884008731	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
882884008732	EamA-like transporter family; Region: EamA; pfam00892
882884008733	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
882884008734	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
882884008735	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
882884008736	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
882884008737	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
882884008738	dimer interface [polypeptide binding]; other site
882884008739	ssDNA binding site [nucleotide binding]; other site
882884008740	tetramer (dimer of dimers) interface [polypeptide binding]; other site
882884008741	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
882884008742	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884008743	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
882884008744	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
882884008745	intersubunit interface [polypeptide binding]; other site
882884008746	active site
882884008747	Zn2+ binding site [ion binding]; other site
882884008748	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
882884008749	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
882884008750	AP (apurinic/apyrimidinic) site pocket; other site
882884008751	DNA interaction; other site
882884008752	Metal-binding active site; metal-binding site
882884008753	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
882884008754	active site
882884008755	dimer interface [polypeptide binding]; other site
882884008756	magnesium binding site [ion binding]; other site
882884008757	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
882884008758	active site
882884008759	phosphorylation site [posttranslational modification]
882884008760	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
882884008761	active site
882884008762	P-loop; other site
882884008763	phosphorylation site [posttranslational modification]
882884008764	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
882884008765	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
882884008766	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
882884008767	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
882884008768	transcriptional repressor UlaR; Provisional; Region: PRK13509
882884008769	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
882884008770	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884008771	esterase; Provisional; Region: PRK10566
882884008772	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
882884008773	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
882884008774	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
882884008775	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884008776	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
882884008777	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
882884008778	FAD binding site [chemical binding]; other site
882884008779	substrate binding site [chemical binding]; other site
882884008780	catalytic residues [active]
882884008781	Glutathionylspermidine synthase preATP-grasp; Region: GSP_synth; cl00503
882884008782	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
882884008783	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
882884008784	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
882884008785	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
882884008786	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
882884008787	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
882884008788	exoribonuclease R; Provisional; Region: PRK11642
882884008789	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
882884008790	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
882884008791	RNB domain; Region: RNB; pfam00773
882884008792	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
882884008793	RNA binding site [nucleotide binding]; other site
882884008794	Predicted transcriptional regulator [Transcription]; Region: COG1959
882884008795	transcriptional repressor NsrR; Provisional; Region: PRK11014
882884008796	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
882884008797	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
882884008798	GDP-binding site [chemical binding]; other site
882884008799	ACT binding site; other site
882884008800	IMP binding site; other site
882884008801	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
882884008802	FtsH protease regulator HflC; Provisional; Region: PRK11029
882884008803	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
882884008804	FtsH protease regulator HflK; Provisional; Region: PRK10930
882884008805	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
882884008806	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
882884008807	GTPase HflX; Provisional; Region: PRK11058
882884008808	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
882884008809	HflX GTPase family; Region: HflX; cd01878
882884008810	G1 box; other site
882884008811	GTP/Mg2+ binding site [chemical binding]; other site
882884008812	Switch I region; other site
882884008813	G2 box; other site
882884008814	G3 box; other site
882884008815	Switch II region; other site
882884008816	G4 box; other site
882884008817	G5 box; other site
882884008818	bacterial Hfq-like; Region: Hfq; cd01716
882884008819	hexamer interface [polypeptide binding]; other site
882884008820	Sm1 motif; other site
882884008821	RNA binding site [nucleotide binding]; other site
882884008822	Sm2 motif; other site
882884008823	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
882884008824	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
882884008825	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
882884008826	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884008827	ATP binding site [chemical binding]; other site
882884008828	Mg2+ binding site [ion binding]; other site
882884008829	G-X-G motif; other site
882884008830	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
882884008831	ATP binding site [chemical binding]; other site
882884008832	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
882884008833	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
882884008834	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
882884008835	active site
882884008836	metal binding site [ion binding]; metal-binding site
882884008837	ADP-binding protein; Provisional; Region: PRK10646
882884008838	putative carbohydrate kinase; Provisional; Region: PRK10565
882884008839	Uncharacterized conserved protein [Function unknown]; Region: COG0062
882884008840	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
882884008841	putative substrate binding site [chemical binding]; other site
882884008842	putative ATP binding site [chemical binding]; other site
882884008843	epoxyqueuosine reductase; Region: TIGR00276
882884008844	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
882884008845	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
882884008846	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884008847	substrate binding pocket [chemical binding]; other site
882884008848	membrane-bound complex binding site; other site
882884008849	hinge residues; other site
882884008850	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
882884008851	catalytic site [active]
882884008852	putative active site [active]
882884008853	putative substrate binding site [chemical binding]; other site
882884008854	dimer interface [polypeptide binding]; other site
882884008855	GTPase RsgA; Reviewed; Region: PRK12288
882884008856	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
882884008857	RNA binding site [nucleotide binding]; other site
882884008858	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
882884008859	GTPase/Zn-binding domain interface [polypeptide binding]; other site
882884008860	GTP/Mg2+ binding site [chemical binding]; other site
882884008861	G4 box; other site
882884008862	G5 box; other site
882884008863	G1 box; other site
882884008864	Switch I region; other site
882884008865	G2 box; other site
882884008866	G3 box; other site
882884008867	Switch II region; other site
882884008868	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
882884008869	putative mechanosensitive channel protein; Provisional; Region: PRK10929
882884008870	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
882884008871	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
882884008872	Mechanosensitive ion channel; Region: MS_channel; pfam00924
882884008873	inner membrane transporter YjeM; Provisional; Region: PRK15238
882884008874	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
882884008875	poxB regulator PoxA; Provisional; Region: PRK09350
882884008876	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
882884008877	motif 1; other site
882884008878	dimer interface [polypeptide binding]; other site
882884008879	active site
882884008880	motif 2; other site
882884008881	motif 3; other site
882884008882	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
882884008883	L-aspartate oxidase; Provisional; Region: PRK06175
882884008884	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
882884008885	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
882884008886	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
882884008887	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
882884008888	D-subunit interface [polypeptide binding]; other site
882884008889	Iron-sulfur protein interface; other site
882884008890	proximal quinone binding site [chemical binding]; other site
882884008891	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
882884008892	Iron-sulfur protein interface; other site
882884008893	proximal quinone binding site [chemical binding]; other site
882884008894	C-subunit interface; other site
882884008895	distal quinone binding site; other site
882884008896	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
882884008897	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
882884008898	multidrug efflux system protein; Provisional; Region: PRK11431
882884008899	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
882884008900	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884008901	DNA binding residues [nucleotide binding]
882884008902	dimerization interface [polypeptide binding]; other site
882884008903	elongation factor P; Validated; Region: PRK00529
882884008904	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
882884008905	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
882884008906	RNA binding site [nucleotide binding]; other site
882884008907	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
882884008908	RNA binding site [nucleotide binding]; other site
882884008909	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
882884008910	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884008911	FeS/SAM binding site; other site
882884008912	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
882884008913	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
882884008914	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
882884008915	ring oligomerisation interface [polypeptide binding]; other site
882884008916	ATP/Mg binding site [chemical binding]; other site
882884008917	stacking interactions; other site
882884008918	hinge regions; other site
882884008919	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
882884008920	oligomerisation interface [polypeptide binding]; other site
882884008921	mobile loop; other site
882884008922	roof hairpin; other site
882884008923	putative transporter; Provisional; Region: PRK11021
882884008924	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
882884008925	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
882884008926	Aspartase; Region: Aspartase; cd01357
882884008927	active sites [active]
882884008928	tetramer interface [polypeptide binding]; other site
882884008929	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
882884008930	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
882884008931	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
882884008932	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
882884008933	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
882884008934	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
882884008935	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
882884008936	DsbD alpha interface [polypeptide binding]; other site
882884008937	catalytic residues [active]
882884008938	putative transcriptional regulator; Provisional; Region: PRK11640
882884008939	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884008940	integrase; Provisional; Region: PRK09692
882884008941	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
882884008942	active site
882884008943	Int/Topo IB signature motif; other site
882884008944	Integrase; Region: Integrase_1; pfam12835
882884008945	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
882884008946	Integrase; Region: Integrase_1; pfam12835
882884008947	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
882884008948	Ash protein family; Region: Phage_ASH; pfam10554
882884008949	AAA ATPase domain; Region: AAA_16; pfam13191
882884008950	Divergent AAA domain; Region: AAA_4; pfam04326
882884008951	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
882884008952	Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg3; cd01282
882884008953	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
882884008954	DNA binding residues [nucleotide binding]
882884008955	putative dimer interface [polypeptide binding]; other site
882884008956	EthD domain; Region: EthD; pfam07110
882884008957	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884008958	Transposase; Region: HTH_Tnp_1; pfam01527
882884008959	AraC family transcriptional regulator; Provisional; Region: PRK15186
882884008960	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884008961	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
882884008962	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884008963	DNA binding residues [nucleotide binding]
882884008964	dimerization interface [polypeptide binding]; other site
882884008965	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
882884008966	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619
882884008967	Walker A/P-loop; other site
882884008968	ATP binding site [chemical binding]; other site
882884008969	Q-loop/lid; other site
882884008970	ABC transporter signature motif; other site
882884008971	Walker B; other site
882884008972	D-loop; other site
882884008973	H-loop/switch region; other site
882884008974	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884008975	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
882884008976	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008977	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884008978	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008979	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008980	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008981	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008982	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884008983	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008984	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008985	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884008986	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008987	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008988	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008989	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884008990	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008991	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008992	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008993	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008994	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008995	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884008996	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008997	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884008998	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
882884008999	SdiA-regulated; Region: SdiA-regulated; cd09971
882884009000	putative active site [active]
882884009001	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
882884009002	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
882884009003	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
882884009004	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
882884009005	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
882884009006	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
882884009007	putative [Fe4-S4] binding site [ion binding]; other site
882884009008	putative molybdopterin cofactor binding site [chemical binding]; other site
882884009009	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
882884009010	putative molybdopterin cofactor binding site; other site
882884009011	sensory histidine kinase DcuS; Provisional; Region: PRK11086
882884009012	PAS domain; Region: PAS; smart00091
882884009013	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884009014	ATP binding site [chemical binding]; other site
882884009015	Mg2+ binding site [ion binding]; other site
882884009016	G-X-G motif; other site
882884009017	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
882884009018	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884009019	active site
882884009020	phosphorylation site [posttranslational modification]
882884009021	intermolecular recognition site; other site
882884009022	dimerization interface [polypeptide binding]; other site
882884009023	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
882884009024	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
882884009025	fumarate hydratase; Provisional; Region: PRK15389
882884009026	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
882884009027	Fumarase C-terminus; Region: Fumerase_C; pfam05683
882884009028	hypothetical protein; Provisional; Region: PRK09867
882884009029	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
882884009030	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884009031	ABC transporter; Region: ABC_tran_2; pfam12848
882884009032	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884009033	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884009034	H+ Antiporter protein; Region: 2A0121; TIGR00900
882884009035	putative substrate translocation pore; other site
882884009036	Cupin-like domain; Region: Cupin_8; pfam13621
882884009037	HEXXH motif domain; Region: mod_HExxH; TIGR04267
882884009038	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
882884009039	ATP binding site [chemical binding]; other site
882884009040	substrate interface [chemical binding]; other site
882884009041	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
882884009042	Cupin-like domain; Region: Cupin_8; pfam13621
882884009043	melibiose:sodium symporter; Provisional; Region: PRK10429
882884009044	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
882884009045	alpha-galactosidase; Provisional; Region: PRK15076
882884009046	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
882884009047	NAD binding site [chemical binding]; other site
882884009048	sugar binding site [chemical binding]; other site
882884009049	divalent metal binding site [ion binding]; other site
882884009050	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
882884009051	dimer interface [polypeptide binding]; other site
882884009052	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
882884009053	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009054	arginine decarboxylase; Provisional; Region: PRK15029
882884009055	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
882884009056	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
882884009057	homodimer interface [polypeptide binding]; other site
882884009058	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884009059	catalytic residue [active]
882884009060	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
882884009061	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
882884009062	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009063	arginine:agmatin antiporter; Provisional; Region: PRK10644
882884009064	putative metal dependent hydrolase; Provisional; Region: PRK11598
882884009065	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
882884009066	Sulfatase; Region: Sulfatase; pfam00884
882884009067	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
882884009068	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884009069	active site
882884009070	phosphorylation site [posttranslational modification]
882884009071	intermolecular recognition site; other site
882884009072	dimerization interface [polypeptide binding]; other site
882884009073	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884009074	DNA binding site [nucleotide binding]
882884009075	sensor protein BasS/PmrB; Provisional; Region: PRK10755
882884009076	HAMP domain; Region: HAMP; pfam00672
882884009077	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884009078	dimer interface [polypeptide binding]; other site
882884009079	phosphorylation site [posttranslational modification]
882884009080	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884009081	ATP binding site [chemical binding]; other site
882884009082	Mg2+ binding site [ion binding]; other site
882884009083	G-X-G motif; other site
882884009084	proline/glycine betaine transporter; Provisional; Region: PRK10642
882884009085	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884009086	putative substrate translocation pore; other site
882884009087	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
882884009088	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
882884009089	PhnA protein; Region: PhnA; pfam03831
882884009090	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
882884009091	dimer interface [polypeptide binding]; other site
882884009092	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
882884009093	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
882884009094	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
882884009095	Walker A/P-loop; other site
882884009096	ATP binding site [chemical binding]; other site
882884009097	Q-loop/lid; other site
882884009098	ABC transporter signature motif; other site
882884009099	Walker B; other site
882884009100	D-loop; other site
882884009101	H-loop/switch region; other site
882884009102	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
882884009103	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
882884009104	substrate binding pocket [chemical binding]; other site
882884009105	membrane-bound complex binding site; other site
882884009106	hinge residues; other site
882884009107	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
882884009108	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884009109	dimer interface [polypeptide binding]; other site
882884009110	conserved gate region; other site
882884009111	putative PBP binding loops; other site
882884009112	ABC-ATPase subunit interface; other site
882884009113	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
882884009114	carbon-phosphorus lyase complex subunit; Validated; Region: phnH; PRK10147
882884009115	Bacterial phosphonate metabolism protein (PhnI); Region: PhnI; pfam05861
882884009116	Phosphonate metabolism protein PhnJ; Region: PhnJ; pfam06007
882884009117	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
882884009118	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884009119	Walker A/P-loop; other site
882884009120	ATP binding site [chemical binding]; other site
882884009121	Q-loop/lid; other site
882884009122	ABC transporter signature motif; other site
882884009123	Walker B; other site
882884009124	D-loop; other site
882884009125	H-loop/switch region; other site
882884009126	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
882884009127	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
882884009128	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884009129	Walker A/P-loop; other site
882884009130	ATP binding site [chemical binding]; other site
882884009131	Q-loop/lid; other site
882884009132	ABC transporter signature motif; other site
882884009133	Walker B; other site
882884009134	D-loop; other site
882884009135	H-loop/switch region; other site
882884009136	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
882884009137	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
882884009138	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
882884009139	active site
882884009140	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
882884009141	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
882884009142	active site
882884009143	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
882884009144	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884009145	Coenzyme A binding pocket [chemical binding]; other site
882884009146	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
882884009147	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
882884009148	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
882884009149	multidrug resistance protein MdtN; Provisional; Region: PRK10476
882884009150	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
882884009151	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884009152	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
882884009153	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
882884009154	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
882884009155	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
882884009156	Sel1-like repeats; Region: SEL1; smart00671
882884009157	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
882884009158	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
882884009159	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
882884009160	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
882884009161	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
882884009162	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
882884009163	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
882884009164	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
882884009165	acetyl-CoA synthetase; Provisional; Region: PRK00174
882884009166	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
882884009167	active site
882884009168	CoA binding site [chemical binding]; other site
882884009169	acyl-activating enzyme (AAE) consensus motif; other site
882884009170	AMP binding site [chemical binding]; other site
882884009171	acetate binding site [chemical binding]; other site
882884009172	Predicted membrane protein [Function unknown]; Region: COG3162
882884009173	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
882884009174	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
882884009175	Na binding site [ion binding]; other site
882884009176	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
882884009177	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
882884009178	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884009179	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884009180	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
882884009181	putative dimerization interface [polypeptide binding]; other site
882884009182	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
882884009183	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
882884009184	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
882884009185	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
882884009186	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
882884009187	DNA binding residues [nucleotide binding]
882884009188	dimer interface [polypeptide binding]; other site
882884009189	[2Fe-2S] cluster binding site [ion binding]; other site
882884009190	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
882884009191	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009192	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
882884009193	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009194	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
882884009195	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884009196	Walker A/P-loop; other site
882884009197	ATP binding site [chemical binding]; other site
882884009198	Q-loop/lid; other site
882884009199	ABC transporter signature motif; other site
882884009200	Walker B; other site
882884009201	D-loop; other site
882884009202	H-loop/switch region; other site
882884009203	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009204	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009205	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009206	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009207	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
882884009208	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009209	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
882884009210	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
882884009211	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009212	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009213	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
882884009214	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009215	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009216	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
882884009217	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009218	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009219	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009220	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009221	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
882884009222	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009223	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009224	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009225	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009226	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009227	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009228	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009229	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
882884009230	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009231	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009232	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009233	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009234	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009235	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009236	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
882884009237	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009238	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
882884009239	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009240	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009241	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
882884009242	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009243	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009244	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009245	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009246	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009247	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009248	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009249	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
882884009250	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009251	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009252	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009253	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009254	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
882884009255	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009256	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
882884009257	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009258	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
882884009259	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
882884009260	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
882884009261	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884009262	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
882884009263	hypothetical protein; Validated; Region: PRK09039
882884009264	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
882884009265	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
882884009266	dimer interface [polypeptide binding]; other site
882884009267	ssDNA binding site [nucleotide binding]; other site
882884009268	tetramer (dimer of dimers) interface [polypeptide binding]; other site
882884009269	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
882884009270	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
882884009271	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
882884009272	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
882884009273	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
882884009274	Uncharacterized conserved protein [Function unknown]; Region: COG0432
882884009275	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
882884009276	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884009277	active site
882884009278	motif I; other site
882884009279	motif II; other site
882884009280	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
882884009281	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884009282	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884009283	homodimer interface [polypeptide binding]; other site
882884009284	catalytic residue [active]
882884009285	alanine racemase; Reviewed; Region: alr; PRK00053
882884009286	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
882884009287	active site
882884009288	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
882884009289	substrate binding site [chemical binding]; other site
882884009290	catalytic residues [active]
882884009291	dimer interface [polypeptide binding]; other site
882884009292	replicative DNA helicase; Provisional; Region: PRK08006
882884009293	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
882884009294	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
882884009295	Walker A motif; other site
882884009296	ATP binding site [chemical binding]; other site
882884009297	Walker B motif; other site
882884009298	DNA binding loops [nucleotide binding]
882884009299	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
882884009300	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
882884009301	NADP binding site [chemical binding]; other site
882884009302	dimer interface [polypeptide binding]; other site
882884009303	phage shock protein G; Reviewed; Region: pspG; PRK09459
882884009304	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
882884009305	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
882884009306	FMN binding site [chemical binding]; other site
882884009307	active site
882884009308	catalytic residues [active]
882884009309	substrate binding site [chemical binding]; other site
882884009310	formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH2; cd08286
882884009311	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
882884009312	catalytic Zn binding site [ion binding]; other site
882884009313	structural Zn binding site [ion binding]; other site
882884009314	NAD(P) binding site [chemical binding]; other site
882884009315	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
882884009316	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
882884009317	metal binding site 2 [ion binding]; metal-binding site
882884009318	putative DNA binding helix; other site
882884009319	metal binding site 1 [ion binding]; metal-binding site
882884009320	dimer interface [polypeptide binding]; other site
882884009321	structural Zn2+ binding site [ion binding]; other site
882884009322	hypothetical protein; Provisional; Region: PRK10428
882884009323	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
882884009324	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
882884009325	LexA repressor; Validated; Region: PRK00215
882884009326	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
882884009327	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
882884009328	Catalytic site [active]
882884009329	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
882884009330	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
882884009331	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
882884009332	putative acyl-acceptor binding pocket; other site
882884009333	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
882884009334	UbiA prenyltransferase family; Region: UbiA; pfam01040
882884009335	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
882884009336	maltose regulon periplasmic protein; Provisional; Region: PRK10564
882884009337	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
882884009338	trimer interface; other site
882884009339	sugar binding site [chemical binding]; other site
882884009340	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
882884009341	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
882884009342	Walker A/P-loop; other site
882884009343	ATP binding site [chemical binding]; other site
882884009344	Q-loop/lid; other site
882884009345	ABC transporter signature motif; other site
882884009346	Walker B; other site
882884009347	D-loop; other site
882884009348	H-loop/switch region; other site
882884009349	TOBE domain; Region: TOBE_2; pfam08402
882884009350	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
882884009351	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
882884009352	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
882884009353	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884009354	dimer interface [polypeptide binding]; other site
882884009355	conserved gate region; other site
882884009356	putative PBP binding loops; other site
882884009357	ABC-ATPase subunit interface; other site
882884009358	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
882884009359	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884009360	dimer interface [polypeptide binding]; other site
882884009361	conserved gate region; other site
882884009362	putative PBP binding loops; other site
882884009363	ABC-ATPase subunit interface; other site
882884009364	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
882884009365	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884009366	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
882884009367	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
882884009368	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
882884009369	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
882884009370	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
882884009371	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
882884009372	active site
882884009373	dimer interface [polypeptide binding]; other site
882884009374	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
882884009375	dimer interface [polypeptide binding]; other site
882884009376	active site
882884009377	aspartate kinase III; Validated; Region: PRK09084
882884009378	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
882884009379	nucleotide binding site [chemical binding]; other site
882884009380	substrate binding site [chemical binding]; other site
882884009381	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
882884009382	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
882884009383	dimer interface [polypeptide binding]; other site
882884009384	hypothetical protein; Provisional; Region: PRK10515
882884009385	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
882884009386	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
882884009387	RNA binding surface [nucleotide binding]; other site
882884009388	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
882884009389	probable active site [active]
882884009390	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
882884009391	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
882884009392	active site pocket [active]
882884009393	oxyanion hole [active]
882884009394	catalytic triad [active]
882884009395	active site nucleophile [active]
882884009396	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
882884009397	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
882884009398	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
882884009399	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
882884009400	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
882884009401	substrate binding pocket [chemical binding]; other site
882884009402	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
882884009403	B12 binding site [chemical binding]; other site
882884009404	cobalt ligand [ion binding]; other site
882884009405	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
882884009406	transcriptional repressor IclR; Provisional; Region: PRK11569
882884009407	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
882884009408	Bacterial transcriptional regulator; Region: IclR; pfam01614
882884009409	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
882884009410	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
882884009411	isocitrate lyase; Provisional; Region: PRK15063
882884009412	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
882884009413	tetramer interface [polypeptide binding]; other site
882884009414	active site
882884009415	Mg2+/Mn2+ binding site [ion binding]; other site
882884009416	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
882884009417	malate synthase A; Region: malate_syn_A; TIGR01344
882884009418	active site
882884009419	homoserine O-succinyltransferase; Provisional; Region: PRK05368
882884009420	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
882884009421	proposed active site lysine [active]
882884009422	conserved cys residue [active]
882884009423	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
882884009424	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884009425	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
882884009426	Coenzyme A binding pocket [chemical binding]; other site
882884009427	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
882884009428	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
882884009429	purine monophosphate binding site [chemical binding]; other site
882884009430	dimer interface [polypeptide binding]; other site
882884009431	putative catalytic residues [active]
882884009432	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
882884009433	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
882884009434	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
882884009435	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
882884009436	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
882884009437	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
882884009438	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884009439	active site
882884009440	phosphorylation site [posttranslational modification]
882884009441	intermolecular recognition site; other site
882884009442	dimerization interface [polypeptide binding]; other site
882884009443	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884009444	Walker A motif; other site
882884009445	ATP binding site [chemical binding]; other site
882884009446	Walker B motif; other site
882884009447	arginine finger; other site
882884009448	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
882884009449	sensor protein ZraS; Provisional; Region: PRK10364
882884009450	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884009451	dimer interface [polypeptide binding]; other site
882884009452	phosphorylation site [posttranslational modification]
882884009453	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884009454	ATP binding site [chemical binding]; other site
882884009455	Mg2+ binding site [ion binding]; other site
882884009456	G-X-G motif; other site
882884009457	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
882884009458	dimer interface [polypeptide binding]; other site
882884009459	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
882884009460	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
882884009461	IHF dimer interface [polypeptide binding]; other site
882884009462	IHF - DNA interface [nucleotide binding]; other site
882884009463	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
882884009464	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
882884009465	Active_site [active]
882884009466	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
882884009467	substrate binding site [chemical binding]; other site
882884009468	active site
882884009469	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
882884009470	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
882884009471	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
882884009472	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
882884009473	putative NADH binding site [chemical binding]; other site
882884009474	putative active site [active]
882884009475	nudix motif; other site
882884009476	putative metal binding site [ion binding]; other site
882884009477	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
882884009478	TPP riboswitch (THI element)
882884009479	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
882884009480	ThiC-associated domain; Region: ThiC-associated; pfam13667
882884009481	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
882884009482	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
882884009483	thiamine phosphate binding site [chemical binding]; other site
882884009484	active site
882884009485	pyrophosphate binding site [ion binding]; other site
882884009486	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
882884009487	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
882884009488	ATP binding site [chemical binding]; other site
882884009489	substrate interface [chemical binding]; other site
882884009490	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
882884009491	thiS-thiF/thiG interaction site; other site
882884009492	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
882884009493	ThiS interaction site; other site
882884009494	putative active site [active]
882884009495	tetramer interface [polypeptide binding]; other site
882884009496	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
882884009497	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884009498	FeS/SAM binding site; other site
882884009499	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
882884009500	type III secretion system protein; Provisional; Region: PRK15384
882884009501	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
882884009502	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
882884009503	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
882884009504	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
882884009505	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
882884009506	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
882884009507	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
882884009508	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
882884009509	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
882884009510	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
882884009511	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
882884009512	DNA binding site [nucleotide binding]
882884009513	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
882884009514	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
882884009515	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
882884009516	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
882884009517	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
882884009518	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
882884009519	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
882884009520	RPB3 interaction site [polypeptide binding]; other site
882884009521	RPB1 interaction site [polypeptide binding]; other site
882884009522	RPB11 interaction site [polypeptide binding]; other site
882884009523	RPB10 interaction site [polypeptide binding]; other site
882884009524	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
882884009525	core dimer interface [polypeptide binding]; other site
882884009526	peripheral dimer interface [polypeptide binding]; other site
882884009527	L10 interface [polypeptide binding]; other site
882884009528	L11 interface [polypeptide binding]; other site
882884009529	putative EF-Tu interaction site [polypeptide binding]; other site
882884009530	putative EF-G interaction site [polypeptide binding]; other site
882884009531	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
882884009532	23S rRNA interface [nucleotide binding]; other site
882884009533	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
882884009534	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
882884009535	mRNA/rRNA interface [nucleotide binding]; other site
882884009536	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
882884009537	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
882884009538	23S rRNA interface [nucleotide binding]; other site
882884009539	L7/L12 interface [polypeptide binding]; other site
882884009540	putative thiostrepton binding site; other site
882884009541	L25 interface [polypeptide binding]; other site
882884009542	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
882884009543	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
882884009544	putative homodimer interface [polypeptide binding]; other site
882884009545	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
882884009546	heterodimer interface [polypeptide binding]; other site
882884009547	homodimer interface [polypeptide binding]; other site
882884009548	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
882884009549	elongation factor Tu; Reviewed; Region: PRK00049
882884009550	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
882884009551	G1 box; other site
882884009552	GEF interaction site [polypeptide binding]; other site
882884009553	GTP/Mg2+ binding site [chemical binding]; other site
882884009554	Switch I region; other site
882884009555	G2 box; other site
882884009556	G3 box; other site
882884009557	Switch II region; other site
882884009558	G4 box; other site
882884009559	G5 box; other site
882884009560	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
882884009561	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
882884009562	Antibiotic Binding Site [chemical binding]; other site
882884009563	pantothenate kinase; Provisional; Region: PRK05439
882884009564	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
882884009565	ATP-binding site [chemical binding]; other site
882884009566	CoA-binding site [chemical binding]; other site
882884009567	Mg2+-binding site [ion binding]; other site
882884009568	Biotin operon repressor [Transcription]; Region: BirA; COG1654
882884009569	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
882884009570	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
882884009571	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
882884009572	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
882884009573	FAD binding domain; Region: FAD_binding_4; pfam01565
882884009574	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
882884009575	glutamate racemase; Provisional; Region: PRK00865
882884009576	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
882884009577	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
882884009578	N-terminal plug; other site
882884009579	ligand-binding site [chemical binding]; other site
882884009580	cobalamin riboswitch
882884009581	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
882884009582	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
882884009583	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884009584	S-adenosylmethionine binding site [chemical binding]; other site
882884009585	hypothetical protein; Provisional; Region: PRK11056
882884009586	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
882884009587	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884009588	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884009589	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
882884009590	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
882884009591	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884009592	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
882884009593	dimerization interface [polypeptide binding]; other site
882884009594	argininosuccinate lyase; Provisional; Region: PRK04833
882884009595	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
882884009596	active sites [active]
882884009597	tetramer interface [polypeptide binding]; other site
882884009598	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
882884009599	nucleotide binding site [chemical binding]; other site
882884009600	N-acetyl-L-glutamate binding site [chemical binding]; other site
882884009601	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
882884009602	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
882884009603	acetylornithine deacetylase; Provisional; Region: PRK05111
882884009604	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
882884009605	metal binding site [ion binding]; metal-binding site
882884009606	putative dimer interface [polypeptide binding]; other site
882884009607	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
882884009608	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
882884009609	hypothetical protein; Provisional; Region: PRK10649
882884009610	Sulfatase; Region: Sulfatase; pfam00884
882884009611	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
882884009612	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009613	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
882884009614	active site
882884009615	intersubunit interactions; other site
882884009616	catalytic residue [active]
882884009617	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
882884009618	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
882884009619	dimer interface [polypeptide binding]; other site
882884009620	active site
882884009621	metal binding site [ion binding]; metal-binding site
882884009622	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
882884009623	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
882884009624	heme binding site [chemical binding]; other site
882884009625	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
882884009626	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
882884009627	FAD binding site [chemical binding]; other site
882884009628	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
882884009629	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
882884009630	active site
882884009631	metal binding site [ion binding]; metal-binding site
882884009632	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
882884009633	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
882884009634	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
882884009635	putative catalytic residues [active]
882884009636	putative nucleotide binding site [chemical binding]; other site
882884009637	putative aspartate binding site [chemical binding]; other site
882884009638	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
882884009639	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
882884009640	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
882884009641	cystathionine gamma-synthase; Provisional; Region: PRK08045
882884009642	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
882884009643	homodimer interface [polypeptide binding]; other site
882884009644	substrate-cofactor binding pocket; other site
882884009645	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884009646	catalytic residue [active]
882884009647	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
882884009648	dimerization interface [polypeptide binding]; other site
882884009649	DNA binding site [nucleotide binding]
882884009650	corepressor binding sites; other site
882884009651	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
882884009652	MFS/sugar transport protein; Region: MFS_2; pfam13347
882884009653	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
882884009654	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
882884009655	primosome assembly protein PriA; Validated; Region: PRK05580
882884009656	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884009657	ATP binding site [chemical binding]; other site
882884009658	putative Mg++ binding site [ion binding]; other site
882884009659	helicase superfamily c-terminal domain; Region: HELICc; smart00490
882884009660	ATP-binding site [chemical binding]; other site
882884009661	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884009662	DNA binding site [nucleotide binding]
882884009663	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
882884009664	domain linker motif; other site
882884009665	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
882884009666	dimerization interface [polypeptide binding]; other site
882884009667	ligand binding site [chemical binding]; other site
882884009668	essential cell division protein FtsN; Provisional; Region: PRK10927
882884009669	cell division protein FtsN; Provisional; Region: PRK12757
882884009670	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
882884009671	active site
882884009672	HslU subunit interaction site [polypeptide binding]; other site
882884009673	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
882884009674	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884009675	Walker A motif; other site
882884009676	ATP binding site [chemical binding]; other site
882884009677	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
882884009678	Walker B motif; other site
882884009679	arginine finger; other site
882884009680	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
882884009681	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
882884009682	UbiA prenyltransferase family; Region: UbiA; pfam01040
882884009683	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
882884009684	septal ring assembly protein ZapB; Provisional; Region: PRK15422
882884009685	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
882884009686	amphipathic channel; other site
882884009687	Asn-Pro-Ala signature motifs; other site
882884009688	glycerol kinase; Provisional; Region: glpK; PRK00047
882884009689	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
882884009690	N- and C-terminal domain interface [polypeptide binding]; other site
882884009691	active site
882884009692	MgATP binding site [chemical binding]; other site
882884009693	catalytic site [active]
882884009694	metal binding site [ion binding]; metal-binding site
882884009695	glycerol binding site [chemical binding]; other site
882884009696	homotetramer interface [polypeptide binding]; other site
882884009697	homodimer interface [polypeptide binding]; other site
882884009698	FBP binding site [chemical binding]; other site
882884009699	protein IIAGlc interface [polypeptide binding]; other site
882884009700	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
882884009701	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
882884009702	putative active site [active]
882884009703	ferredoxin-NADP reductase; Provisional; Region: PRK10926
882884009704	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
882884009705	FAD binding pocket [chemical binding]; other site
882884009706	FAD binding motif [chemical binding]; other site
882884009707	phosphate binding motif [ion binding]; other site
882884009708	beta-alpha-beta structure motif; other site
882884009709	NAD binding pocket [chemical binding]; other site
882884009710	Predicted membrane protein [Function unknown]; Region: COG3152
882884009711	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
882884009712	triosephosphate isomerase; Provisional; Region: PRK14567
882884009713	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
882884009714	substrate binding site [chemical binding]; other site
882884009715	dimer interface [polypeptide binding]; other site
882884009716	catalytic triad [active]
882884009717	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
882884009718	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
882884009719	transmembrane helices; other site
882884009720	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
882884009721	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
882884009722	transmembrane helices; other site
882884009723	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
882884009724	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
882884009725	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884009726	membrane-bound complex binding site; other site
882884009727	hinge residues; other site
882884009728	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
882884009729	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
882884009730	active site
882884009731	ADP/pyrophosphate binding site [chemical binding]; other site
882884009732	dimerization interface [polypeptide binding]; other site
882884009733	allosteric effector site; other site
882884009734	fructose-1,6-bisphosphate binding site; other site
882884009735	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
882884009736	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
882884009737	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
882884009738	dimer interface [polypeptide binding]; other site
882884009739	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
882884009740	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884009741	active site
882884009742	intermolecular recognition site; other site
882884009743	dimerization interface [polypeptide binding]; other site
882884009744	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884009745	DNA binding site [nucleotide binding]
882884009746	two-component sensor protein; Provisional; Region: cpxA; PRK09470
882884009747	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884009748	dimerization interface [polypeptide binding]; other site
882884009749	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884009750	dimer interface [polypeptide binding]; other site
882884009751	phosphorylation site [posttranslational modification]
882884009752	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884009753	ATP binding site [chemical binding]; other site
882884009754	Mg2+ binding site [ion binding]; other site
882884009755	G-X-G motif; other site
882884009756	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
882884009757	MOSC domain; Region: MOSC; pfam03473
882884009758	3-alpha domain; Region: 3-alpha; pfam03475
882884009759	superoxide dismutase; Provisional; Region: PRK10925
882884009760	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
882884009761	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
882884009762	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
882884009763	Homeodomain-like domain; Region: HTH_23; pfam13384
882884009764	Winged helix-turn helix; Region: HTH_29; pfam13551
882884009765	Homeodomain-like domain; Region: HTH_32; pfam13565
882884009766	Winged helix-turn helix; Region: HTH_33; pfam13592
882884009767	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
882884009768	DDE superfamily endonuclease; Region: DDE_3; pfam13358
882884009769	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
882884009770	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
882884009771	transcriptional activator RhaR; Provisional; Region: PRK13502
882884009772	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
882884009773	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009774	transcriptional activator RhaS; Provisional; Region: PRK13503
882884009775	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
882884009776	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009777	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009778	rhamnulokinase; Provisional; Region: rhaB; PRK10640
882884009779	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
882884009780	N- and C-terminal domain interface [polypeptide binding]; other site
882884009781	active site
882884009782	carbohydrate binding site [chemical binding]; other site
882884009783	ATP binding site [chemical binding]; other site
882884009784	L-rhamnose isomerase; Provisional; Region: PRK01076
882884009785	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
882884009786	intersubunit interface [polypeptide binding]; other site
882884009787	active site
882884009788	Zn2+ binding site [ion binding]; other site
882884009789	lactaldehyde reductase; Region: lactal_redase; TIGR02638
882884009790	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
882884009791	dimer interface [polypeptide binding]; other site
882884009792	active site
882884009793	metal binding site [ion binding]; metal-binding site
882884009794	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
882884009795	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
882884009796	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884009797	non-specific DNA binding site [nucleotide binding]; other site
882884009798	salt bridge; other site
882884009799	sequence-specific DNA binding site [nucleotide binding]; other site
882884009800	Cupin domain; Region: Cupin_2; cl17218
882884009801	AzlC protein; Region: AzlC; cl00570
882884009802	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
882884009803	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
882884009804	active site
882884009805	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
882884009806	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
882884009807	active site
882884009808	P-loop; other site
882884009809	phosphorylation site [posttranslational modification]
882884009810	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
882884009811	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425
882884009812	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425
882884009813	putative frv operon regulatory protein; Provisional; Region: PRK09863
882884009814	putative frv operon regulatory protein; Provisional; Region: PRK09863
882884009815	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884009816	HlyD family secretion protein; Region: HlyD; pfam00529
882884009817	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
882884009818	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884009819	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
882884009820	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
882884009821	putative active site [active]
882884009822	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
882884009823	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884009824	Walker A/P-loop; other site
882884009825	ATP binding site [chemical binding]; other site
882884009826	Q-loop/lid; other site
882884009827	ABC transporter signature motif; other site
882884009828	Walker B; other site
882884009829	D-loop; other site
882884009830	H-loop/switch region; other site
882884009831	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009832	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
882884009833	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884009834	Outer membrane lipoprotein OmlA (small protein A) [Cell envelope biogenesis, outer membrane]; Region: OlmA; COG2913
882884009835	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
882884009836	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
882884009837	ligand binding site [chemical binding]; other site
882884009838	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
882884009839	trimer interface [polypeptide binding]; other site
882884009840	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
882884009841	trimer interface [polypeptide binding]; other site
882884009842	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
882884009843	trimer interface [polypeptide binding]; other site
882884009844	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
882884009845	Xylella fastidiosa surface protein related; Region: X_fast-SP_rel; pfam06669
882884009846	YadA-like C-terminal region; Region: YadA; pfam03895
882884009847	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
882884009848	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
882884009849	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
882884009850	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
882884009851	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
882884009852	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
882884009853	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
882884009854	Predicted transcriptional regulator [Transcription]; Region: COG2944
882884009855	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884009856	non-specific DNA binding site [nucleotide binding]; other site
882884009857	salt bridge; other site
882884009858	sequence-specific DNA binding site [nucleotide binding]; other site
882884009859	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
882884009860	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
882884009861	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
882884009862	substrate binding pocket [chemical binding]; other site
882884009863	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884009864	Coenzyme A binding pocket [chemical binding]; other site
882884009865	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
882884009866	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
882884009867	putative active site [active]
882884009868	dimerization interface [polypeptide binding]; other site
882884009869	putative tRNAtyr binding site [nucleotide binding]; other site
882884009870	hypothetical protein; Reviewed; Region: PRK01637
882884009871	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
882884009872	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884009873	motif II; other site
882884009874	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
882884009875	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
882884009876	putative DNA binding site [nucleotide binding]; other site
882884009877	putative Zn2+ binding site [ion binding]; other site
882884009878	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884009879	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
882884009880	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
882884009881	substrate binding site [chemical binding]; other site
882884009882	ATP binding site [chemical binding]; other site
882884009883	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
882884009884	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
882884009885	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
882884009886	catalytic residue [active]
882884009887	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
882884009888	dimerization interface [polypeptide binding]; other site
882884009889	putative active cleft [active]
882884009890	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
882884009891	active site
882884009892	catalytic residues [active]
882884009893	alpha-glucosidase; Provisional; Region: PRK10426
882884009894	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
882884009895	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
882884009896	putative active site [active]
882884009897	putative catalytic site [active]
882884009898	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
882884009899	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
882884009900	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
882884009901	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884009902	putative substrate translocation pore; other site
882884009903	outer membrane porin L; Provisional; Region: ompL; PRK09980
882884009904	GTP-binding protein; Provisional; Region: PRK10218
882884009905	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
882884009906	G1 box; other site
882884009907	putative GEF interaction site [polypeptide binding]; other site
882884009908	GTP/Mg2+ binding site [chemical binding]; other site
882884009909	Switch I region; other site
882884009910	G2 box; other site
882884009911	G3 box; other site
882884009912	Switch II region; other site
882884009913	G4 box; other site
882884009914	G5 box; other site
882884009915	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
882884009916	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
882884009917	glutamine synthetase; Provisional; Region: glnA; PRK09469
882884009918	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
882884009919	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
882884009920	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
882884009921	PAS domain; Region: PAS; smart00091
882884009922	putative active site [active]
882884009923	heme pocket [chemical binding]; other site
882884009924	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884009925	dimer interface [polypeptide binding]; other site
882884009926	phosphorylation site [posttranslational modification]
882884009927	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884009928	ATP binding site [chemical binding]; other site
882884009929	Mg2+ binding site [ion binding]; other site
882884009930	G-X-G motif; other site
882884009931	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
882884009932	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884009933	active site
882884009934	phosphorylation site [posttranslational modification]
882884009935	intermolecular recognition site; other site
882884009936	dimerization interface [polypeptide binding]; other site
882884009937	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884009938	Walker A motif; other site
882884009939	ATP binding site [chemical binding]; other site
882884009940	Walker B motif; other site
882884009941	arginine finger; other site
882884009942	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
882884009943	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
882884009944	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884009945	FeS/SAM binding site; other site
882884009946	HemN C-terminal domain; Region: HemN_C; pfam06969
882884009947	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
882884009948	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
882884009949	G1 box; other site
882884009950	GTP/Mg2+ binding site [chemical binding]; other site
882884009951	Switch I region; other site
882884009952	G2 box; other site
882884009953	G3 box; other site
882884009954	Switch II region; other site
882884009955	G4 box; other site
882884009956	G5 box; other site
882884009957	DNA polymerase I; Provisional; Region: PRK05755
882884009958	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
882884009959	active site
882884009960	metal binding site 1 [ion binding]; metal-binding site
882884009961	putative 5' ssDNA interaction site; other site
882884009962	metal binding site 3; metal-binding site
882884009963	metal binding site 2 [ion binding]; metal-binding site
882884009964	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
882884009965	putative DNA binding site [nucleotide binding]; other site
882884009966	putative metal binding site [ion binding]; other site
882884009967	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
882884009968	active site
882884009969	catalytic site [active]
882884009970	substrate binding site [chemical binding]; other site
882884009971	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
882884009972	active site
882884009973	DNA binding site [nucleotide binding]
882884009974	catalytic site [active]
882884009975	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
882884009976	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
882884009977	putative acyl-acceptor binding pocket; other site
882884009978	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
882884009979	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
882884009980	catalytic residues [active]
882884009981	hinge region; other site
882884009982	alpha helical domain; other site
882884009983	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
882884009984	serine/threonine protein kinase; Provisional; Region: PRK11768
882884009985	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
882884009986	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
882884009987	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
882884009988	GTP binding site; other site
882884009989	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
882884009990	Walker A motif; other site
882884009991	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
882884009992	potassium transporter; Provisional; Region: PRK10750
882884009993	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
882884009994	hypothetical protein; Provisional; Region: PRK11568
882884009995	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
882884009996	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
882884009997	proline dipeptidase; Provisional; Region: PRK13607
882884009998	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
882884009999	active site
882884010000	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
882884010001	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
882884010002	substrate binding site [chemical binding]; other site
882884010003	oxyanion hole (OAH) forming residues; other site
882884010004	trimer interface [polypeptide binding]; other site
882884010005	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
882884010006	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
882884010007	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
882884010008	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
882884010009	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
882884010010	dimer interface [polypeptide binding]; other site
882884010011	active site
882884010012	FMN reductase; Validated; Region: fre; PRK08051
882884010013	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
882884010014	FAD binding pocket [chemical binding]; other site
882884010015	FAD binding motif [chemical binding]; other site
882884010016	phosphate binding motif [ion binding]; other site
882884010017	beta-alpha-beta structure motif; other site
882884010018	NAD binding pocket [chemical binding]; other site
882884010019	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
882884010020	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
882884010021	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
882884010022	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
882884010023	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
882884010024	active site
882884010025	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
882884010026	sec-independent translocase; Provisional; Region: PRK01770
882884010027	sec-independent translocase; Provisional; Region: tatB; PRK00404
882884010028	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
882884010029	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
882884010030	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
882884010031	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
882884010032	SCP-2 sterol transfer family; Region: SCP2; pfam02036
882884010033	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
882884010034	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884010035	S-adenosylmethionine binding site [chemical binding]; other site
882884010036	DNA recombination protein RmuC; Provisional; Region: PRK10361
882884010037	RmuC family; Region: RmuC; pfam02646
882884010038	uridine phosphorylase; Provisional; Region: PRK11178
882884010039	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
882884010040	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
882884010041	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
882884010042	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884010043	FeS/SAM binding site; other site
882884010044	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
882884010045	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
882884010046	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
882884010047	THF binding site; other site
882884010048	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
882884010049	substrate binding site [chemical binding]; other site
882884010050	THF binding site; other site
882884010051	zinc-binding site [ion binding]; other site
882884010052	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
882884010053	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884010054	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
882884010055	putative dimerization interface [polypeptide binding]; other site
882884010056	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
882884010057	EamA-like transporter family; Region: EamA; pfam00892
882884010058	putative hydrolase; Provisional; Region: PRK10976
882884010059	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884010060	active site
882884010061	motif I; other site
882884010062	motif II; other site
882884010063	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884010064	lysophospholipase L2; Provisional; Region: PRK10749
882884010065	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
882884010066	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
882884010067	threonine efflux system; Provisional; Region: PRK10229
882884010068	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
882884010069	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884010070	ATP binding site [chemical binding]; other site
882884010071	putative Mg++ binding site [ion binding]; other site
882884010072	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884010073	nucleotide binding region [chemical binding]; other site
882884010074	ATP-binding site [chemical binding]; other site
882884010075	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
882884010076	HRDC domain; Region: HRDC; pfam00570
882884010077	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
882884010078	dimerization interface [polypeptide binding]; other site
882884010079	substrate binding site [chemical binding]; other site
882884010080	active site
882884010081	calcium binding site [ion binding]; other site
882884010082	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
882884010083	CoenzymeA binding site [chemical binding]; other site
882884010084	subunit interaction site [polypeptide binding]; other site
882884010085	PHB binding site; other site
882884010086	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
882884010087	EamA-like transporter family; Region: EamA; cl17759
882884010088	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
882884010089	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
882884010090	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
882884010091	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
882884010092	Cl binding site [ion binding]; other site
882884010093	oligomer interface [polypeptide binding]; other site
882884010094	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
882884010095	Part of AAA domain; Region: AAA_19; pfam13245
882884010096	Family description; Region: UvrD_C_2; pfam13538
882884010097	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
882884010098	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884010099	motif II; other site
882884010100	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
882884010101	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
882884010102	active site
882884010103	Int/Topo IB signature motif; other site
882884010104	hypothetical protein; Provisional; Region: PRK10963
882884010105	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
882884010106	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
882884010107	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
882884010108	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
882884010109	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
882884010110	putative iron binding site [ion binding]; other site
882884010111	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
882884010112	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
882884010113	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
882884010114	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
882884010115	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
882884010116	domain interfaces; other site
882884010117	active site
882884010118	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
882884010119	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
882884010120	active site
882884010121	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
882884010122	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
882884010123	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
882884010124	HemY protein N-terminus; Region: HemY_N; pfam07219
882884010125	putative transport protein YifK; Provisional; Region: PRK10746
882884010126	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
882884010127	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
882884010128	putative common antigen polymerase; Provisional; Region: PRK02975
882884010129	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
882884010130	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
882884010131	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
882884010132	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
882884010133	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
882884010134	inhibitor-cofactor binding pocket; inhibition site
882884010135	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884010136	catalytic residue [active]
882884010137	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
882884010138	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
882884010139	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
882884010140	substrate binding site; other site
882884010141	tetramer interface; other site
882884010142	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
882884010143	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
882884010144	NAD binding site [chemical binding]; other site
882884010145	substrate binding site [chemical binding]; other site
882884010146	homodimer interface [polypeptide binding]; other site
882884010147	active site
882884010148	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
882884010149	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
882884010150	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
882884010151	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
882884010152	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
882884010153	homodimer interface [polypeptide binding]; other site
882884010154	active site
882884010155	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
882884010156	Chain length determinant protein; Region: Wzz; pfam02706
882884010157	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
882884010158	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
882884010159	Mg++ binding site [ion binding]; other site
882884010160	putative catalytic motif [active]
882884010161	substrate binding site [chemical binding]; other site
882884010162	transcription termination factor Rho; Provisional; Region: rho; PRK09376
882884010163	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
882884010164	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
882884010165	RNA binding site [nucleotide binding]; other site
882884010166	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
882884010167	multimer interface [polypeptide binding]; other site
882884010168	Walker A motif; other site
882884010169	ATP binding site [chemical binding]; other site
882884010170	Walker B motif; other site
882884010171	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
882884010172	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
882884010173	catalytic residues [active]
882884010174	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
882884010175	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
882884010176	ATP binding site [chemical binding]; other site
882884010177	Mg++ binding site [ion binding]; other site
882884010178	motif III; other site
882884010179	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884010180	nucleotide binding region [chemical binding]; other site
882884010181	ATP-binding site [chemical binding]; other site
882884010182	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
882884010183	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
882884010184	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
882884010185	Part of AAA domain; Region: AAA_19; pfam13245
882884010186	Family description; Region: UvrD_C_2; pfam13538
882884010187	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
882884010188	uridine phosphorylase; Provisional; Region: PRK11178
882884010189	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
882884010190	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
882884010191	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
882884010192	ligand binding site [chemical binding]; other site
882884010193	flexible hinge region; other site
882884010194	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
882884010195	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
882884010196	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
882884010197	ketol-acid reductoisomerase; Validated; Region: PRK05225
882884010198	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
882884010199	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
882884010200	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
882884010201	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884010202	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
882884010203	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
882884010204	putative dimerization interface [polypeptide binding]; other site
882884010205	threonine dehydratase; Reviewed; Region: PRK09224
882884010206	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
882884010207	tetramer interface [polypeptide binding]; other site
882884010208	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884010209	catalytic residue [active]
882884010210	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
882884010211	putative Ile/Val binding site [chemical binding]; other site
882884010212	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
882884010213	putative Ile/Val binding site [chemical binding]; other site
882884010214	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
882884010215	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
882884010216	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
882884010217	homodimer interface [polypeptide binding]; other site
882884010218	substrate-cofactor binding pocket; other site
882884010219	catalytic residue [active]
882884010220	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
882884010221	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
882884010222	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
882884010223	PYR/PP interface [polypeptide binding]; other site
882884010224	dimer interface [polypeptide binding]; other site
882884010225	TPP binding site [chemical binding]; other site
882884010226	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
882884010227	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
882884010228	TPP-binding site [chemical binding]; other site
882884010229	dimer interface [polypeptide binding]; other site
882884010230	putative ATP-dependent protease; Provisional; Region: PRK09862
882884010231	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
882884010232	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884010233	Walker A motif; other site
882884010234	ATP binding site [chemical binding]; other site
882884010235	Walker B motif; other site
882884010236	arginine finger; other site
882884010237	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
882884010238	hypothetical protein; Provisional; Region: PRK11027
882884010239	transcriptional regulator HdfR; Provisional; Region: PRK03601
882884010240	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884010241	LysR substrate binding domain; Region: LysR_substrate; pfam03466
882884010242	dimerization interface [polypeptide binding]; other site
882884010243	Transcriptional regulators [Transcription]; Region: FadR; COG2186
882884010244	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884010245	DNA-binding site [nucleotide binding]; DNA binding site
882884010246	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
882884010247	putative transporter; Provisional; Region: PRK10504
882884010248	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884010249	putative substrate translocation pore; other site
882884010250	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884010251	transcriptional repressor RbsR; Provisional; Region: PRK10423
882884010252	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884010253	DNA binding site [nucleotide binding]
882884010254	domain linker motif; other site
882884010255	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
882884010256	dimerization interface [polypeptide binding]; other site
882884010257	ligand binding site [chemical binding]; other site
882884010258	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
882884010259	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
882884010260	substrate binding site [chemical binding]; other site
882884010261	dimer interface [polypeptide binding]; other site
882884010262	ATP binding site [chemical binding]; other site
882884010263	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
882884010264	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
882884010265	ligand binding site [chemical binding]; other site
882884010266	dimerization interface [polypeptide binding]; other site
882884010267	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
882884010268	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
882884010269	TM-ABC transporter signature motif; other site
882884010270	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
882884010271	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
882884010272	Walker A/P-loop; other site
882884010273	ATP binding site [chemical binding]; other site
882884010274	Q-loop/lid; other site
882884010275	ABC transporter signature motif; other site
882884010276	Walker B; other site
882884010277	D-loop; other site
882884010278	H-loop/switch region; other site
882884010279	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
882884010280	D-ribose pyranase; Provisional; Region: PRK11797
882884010281	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
882884010282	potassium uptake protein; Region: kup; TIGR00794
882884010283	regulatory ATPase RavA; Provisional; Region: PRK13531
882884010284	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884010285	Walker A motif; other site
882884010286	ATP binding site [chemical binding]; other site
882884010287	Walker B motif; other site
882884010288	arginine finger; other site
882884010289	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
882884010290	hypothetical protein; Provisional; Region: yieM; PRK10997
882884010291	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
882884010292	metal ion-dependent adhesion site (MIDAS); other site
882884010293	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
882884010294	dimer interface [polypeptide binding]; other site
882884010295	active site
882884010296	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
882884010297	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
882884010298	putative DNA binding site [nucleotide binding]; other site
882884010299	putative Zn2+ binding site [ion binding]; other site
882884010300	AsnC family; Region: AsnC_trans_reg; pfam01037
882884010301	FMN-binding protein MioC; Provisional; Region: PRK09004
882884010302	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
882884010303	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
882884010304	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
882884010305	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
882884010306	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884010307	S-adenosylmethionine binding site [chemical binding]; other site
882884010308	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
882884010309	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
882884010310	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
882884010311	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
882884010312	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
882884010313	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
882884010314	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
882884010315	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
882884010316	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
882884010317	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
882884010318	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
882884010319	beta subunit interaction interface [polypeptide binding]; other site
882884010320	Walker A motif; other site
882884010321	ATP binding site [chemical binding]; other site
882884010322	Walker B motif; other site
882884010323	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
882884010324	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
882884010325	core domain interface [polypeptide binding]; other site
882884010326	delta subunit interface [polypeptide binding]; other site
882884010327	epsilon subunit interface [polypeptide binding]; other site
882884010328	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
882884010329	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
882884010330	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
882884010331	alpha subunit interaction interface [polypeptide binding]; other site
882884010332	Walker A motif; other site
882884010333	ATP binding site [chemical binding]; other site
882884010334	Walker B motif; other site
882884010335	inhibitor binding site; inhibition site
882884010336	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
882884010337	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
882884010338	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
882884010339	gamma subunit interface [polypeptide binding]; other site
882884010340	epsilon subunit interface [polypeptide binding]; other site
882884010341	LBP interface [polypeptide binding]; other site
882884010342	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
882884010343	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
882884010344	Substrate binding site; other site
882884010345	Mg++ binding site; other site
882884010346	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
882884010347	active site
882884010348	substrate binding site [chemical binding]; other site
882884010349	CoA binding site [chemical binding]; other site
882884010350	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
882884010351	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
882884010352	glutaminase active site [active]
882884010353	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
882884010354	dimer interface [polypeptide binding]; other site
882884010355	active site
882884010356	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
882884010357	dimer interface [polypeptide binding]; other site
882884010358	active site
882884010359	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
882884010360	substrate binding pocket [chemical binding]; other site
882884010361	membrane-bound complex binding site; other site
882884010362	hinge residues; other site
882884010363	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
882884010364	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884010365	dimer interface [polypeptide binding]; other site
882884010366	conserved gate region; other site
882884010367	putative PBP binding loops; other site
882884010368	ABC-ATPase subunit interface; other site
882884010369	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
882884010370	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884010371	dimer interface [polypeptide binding]; other site
882884010372	conserved gate region; other site
882884010373	putative PBP binding loops; other site
882884010374	ABC-ATPase subunit interface; other site
882884010375	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
882884010376	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
882884010377	Walker A/P-loop; other site
882884010378	ATP binding site [chemical binding]; other site
882884010379	Q-loop/lid; other site
882884010380	ABC transporter signature motif; other site
882884010381	Walker B; other site
882884010382	D-loop; other site
882884010383	H-loop/switch region; other site
882884010384	transcriptional regulator PhoU; Provisional; Region: PRK11115
882884010385	PhoU domain; Region: PhoU; pfam01895
882884010386	PhoU domain; Region: PhoU; pfam01895
882884010387	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
882884010388	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884010389	active site
882884010390	motif I; other site
882884010391	motif II; other site
882884010392	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
882884010393	Predicted flavoprotein [General function prediction only]; Region: COG0431
882884010394	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
882884010395	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
882884010396	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
882884010397	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884010398	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
882884010399	substrate binding pocket [chemical binding]; other site
882884010400	dimerization interface [polypeptide binding]; other site
882884010401	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
882884010402	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884010403	putative substrate translocation pore; other site
882884010404	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
882884010405	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
882884010406	trmE is a tRNA modification GTPase; Region: trmE; cd04164
882884010407	G1 box; other site
882884010408	GTP/Mg2+ binding site [chemical binding]; other site
882884010409	Switch I region; other site
882884010410	G2 box; other site
882884010411	Switch II region; other site
882884010412	G3 box; other site
882884010413	G4 box; other site
882884010414	G5 box; other site
882884010415	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
882884010416	membrane protein insertase; Provisional; Region: PRK01318
882884010417	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
882884010418	ribonuclease P; Reviewed; Region: rnpA; PRK01732
882884010419	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
882884010420	DnaA N-terminal domain; Region: DnaA_N; pfam11638
882884010421	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
882884010422	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884010423	Walker A motif; other site
882884010424	ATP binding site [chemical binding]; other site
882884010425	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
882884010426	Walker B motif; other site
882884010427	arginine finger; other site
882884010428	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
882884010429	DnaA box-binding interface [nucleotide binding]; other site
882884010430	DNA polymerase III subunit beta; Validated; Region: PRK05643
882884010431	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
882884010432	putative DNA binding surface [nucleotide binding]; other site
882884010433	dimer interface [polypeptide binding]; other site
882884010434	beta-clamp/clamp loader binding surface; other site
882884010435	beta-clamp/translesion DNA polymerase binding surface; other site
882884010436	recF protein; Region: recf; TIGR00611
882884010437	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884010438	Walker A/P-loop; other site
882884010439	ATP binding site [chemical binding]; other site
882884010440	Q-loop/lid; other site
882884010441	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884010442	ABC transporter signature motif; other site
882884010443	Walker B; other site
882884010444	D-loop; other site
882884010445	H-loop/switch region; other site
882884010446	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
882884010447	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884010448	Mg2+ binding site [ion binding]; other site
882884010449	G-X-G motif; other site
882884010450	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
882884010451	anchoring element; other site
882884010452	dimer interface [polypeptide binding]; other site
882884010453	ATP binding site [chemical binding]; other site
882884010454	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
882884010455	active site
882884010456	putative metal-binding site [ion binding]; other site
882884010457	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
882884010458	sugar phosphate phosphatase; Provisional; Region: PRK10513
882884010459	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884010460	active site
882884010461	motif I; other site
882884010462	motif II; other site
882884010463	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884010464	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
882884010465	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884010466	dimer interface [polypeptide binding]; other site
882884010467	phosphorylation site [posttranslational modification]
882884010468	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884010469	ATP binding site [chemical binding]; other site
882884010470	Mg2+ binding site [ion binding]; other site
882884010471	G-X-G motif; other site
882884010472	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884010473	active site
882884010474	phosphorylation site [posttranslational modification]
882884010475	intermolecular recognition site; other site
882884010476	dimerization interface [polypeptide binding]; other site
882884010477	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
882884010478	putative binding surface; other site
882884010479	active site
882884010480	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
882884010481	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
882884010482	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
882884010483	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884010484	active site
882884010485	phosphorylation site [posttranslational modification]
882884010486	intermolecular recognition site; other site
882884010487	dimerization interface [polypeptide binding]; other site
882884010488	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884010489	DNA binding site [nucleotide binding]
882884010490	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
882884010491	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
882884010492	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
882884010493	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
882884010494	molybdopterin cofactor binding site [chemical binding]; other site
882884010495	substrate binding site [chemical binding]; other site
882884010496	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
882884010497	molybdopterin cofactor binding site; other site
882884010498	chaperone protein TorD; Validated; Region: torD; PRK04976
882884010499	Haem-binding domain; Region: Haem_bd; pfam14376
882884010500	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
882884010501	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
882884010502	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
882884010503	Walker A/P-loop; other site
882884010504	ATP binding site [chemical binding]; other site
882884010505	Q-loop/lid; other site
882884010506	ABC transporter signature motif; other site
882884010507	Walker B; other site
882884010508	D-loop; other site
882884010509	H-loop/switch region; other site
882884010510	heme exporter protein CcmB; Region: ccmB; TIGR01190
882884010511	heme exporter protein CcmC; Region: ccmC; TIGR01191
882884010512	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
882884010513	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
882884010514	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
882884010515	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
882884010516	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
882884010517	catalytic residues [active]
882884010518	central insert; other site
882884010519	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
882884010520	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
882884010521	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
882884010522	hypothetical protein; Provisional; Region: PRK11616
882884010523	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
882884010524	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
882884010525	putative dimer interface [polypeptide binding]; other site
882884010526	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
882884010527	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
882884010528	putative dimer interface [polypeptide binding]; other site
882884010529	putative transporter; Validated; Region: PRK03818
882884010530	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
882884010531	TrkA-C domain; Region: TrkA_C; pfam02080
882884010532	TrkA-C domain; Region: TrkA_C; pfam02080
882884010533	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
882884010534	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
882884010535	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884010536	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
882884010537	putative transporter; Provisional; Region: PRK10484
882884010538	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
882884010539	Na binding site [ion binding]; other site
882884010540	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884010541	Sulfatase; Region: Sulfatase; pfam00884
882884010542	Predicted membrane protein [Function unknown]; Region: COG2149
882884010543	Domain of unknown function (DUF202); Region: DUF202; pfam02656
882884010544	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
882884010545	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
882884010546	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
882884010547	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
882884010548	catalytic residue [active]
882884010549	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
882884010550	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
882884010551	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884010552	putative substrate translocation pore; other site
882884010553	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
882884010554	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
882884010555	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
882884010556	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
882884010557	PYR/PP interface [polypeptide binding]; other site
882884010558	dimer interface [polypeptide binding]; other site
882884010559	TPP binding site [chemical binding]; other site
882884010560	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
882884010561	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
882884010562	TPP-binding site [chemical binding]; other site
882884010563	dimer interface [polypeptide binding]; other site
882884010564	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
882884010565	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
882884010566	putative valine binding site [chemical binding]; other site
882884010567	dimer interface [polypeptide binding]; other site
882884010568	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
882884010569	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
882884010570	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884010571	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
882884010572	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
882884010573	substrate binding site [chemical binding]; other site
882884010574	dimer interface [polypeptide binding]; other site
882884010575	ATP binding site [chemical binding]; other site
882884010576	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
882884010577	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884010578	putative substrate translocation pore; other site
882884010579	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
882884010580	active site
882884010581	catalytic residues [active]
882884010582	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
882884010583	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884010584	active site
882884010585	phosphorylation site [posttranslational modification]
882884010586	intermolecular recognition site; other site
882884010587	dimerization interface [polypeptide binding]; other site
882884010588	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884010589	DNA binding residues [nucleotide binding]
882884010590	dimerization interface [polypeptide binding]; other site
882884010591	sensory histidine kinase UhpB; Provisional; Region: PRK11644
882884010592	MASE1; Region: MASE1; pfam05231
882884010593	Histidine kinase; Region: HisKA_3; pfam07730
882884010594	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884010595	ATP binding site [chemical binding]; other site
882884010596	Mg2+ binding site [ion binding]; other site
882884010597	G-X-G motif; other site
882884010598	regulatory protein UhpC; Provisional; Region: PRK11663
882884010599	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884010600	putative substrate translocation pore; other site
882884010601	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
882884010602	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884010603	putative substrate translocation pore; other site
882884010604	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
882884010605	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
882884010606	EamA-like transporter family; Region: EamA; pfam00892
882884010607	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
882884010608	EamA-like transporter family; Region: EamA; cl17759
882884010609	magnesium transport protein MgtC; Provisional; Region: PRK15385
882884010610	MgtC family; Region: MgtC; pfam02308
882884010611	magnesium-transporting ATPase; Provisional; Region: PRK15122
882884010612	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
882884010613	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
882884010614	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
882884010615	Soluble P-type ATPase [General function prediction only]; Region: COG4087
882884010616	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
882884010617	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
882884010618	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
882884010619	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
882884010620	active site
882884010621	metal binding site [ion binding]; metal-binding site
882884010622	interdomain interaction site; other site
882884010623	D5 N terminal like; Region: D5_N; smart00885
882884010624	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
882884010625	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
882884010626	Ash protein family; Region: Phage_ASH; pfam10554
882884010627	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
882884010628	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
882884010629	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
882884010630	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
882884010631	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
882884010632	putative active site [active]
882884010633	putative NTP binding site [chemical binding]; other site
882884010634	putative nucleic acid binding site [nucleotide binding]; other site
882884010635	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
882884010636	integrase; Provisional; Region: PRK09692
882884010637	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
882884010638	active site
882884010639	Int/Topo IB signature motif; other site
882884010640	putative transporter; Provisional; Region: PRK11462
882884010641	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
882884010642	putative alpha-glucosidase; Provisional; Region: PRK10658
882884010643	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
882884010644	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
882884010645	active site
882884010646	homotrimer interface [polypeptide binding]; other site
882884010647	catalytic site [active]
882884010648	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
882884010649	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
882884010650	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
882884010651	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
882884010652	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
882884010653	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
882884010654	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
882884010655	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
882884010656	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
882884010657	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
882884010658	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
882884010659	AsmA family; Region: AsmA; pfam05170
882884010660	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
882884010661	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
882884010662	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
882884010663	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
882884010664	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
882884010665	generic binding surface II; other site
882884010666	ssDNA binding site; other site
882884010667	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
882884010668	ATP binding site [chemical binding]; other site
882884010669	putative Mg++ binding site [ion binding]; other site
882884010670	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884010671	nucleotide binding region [chemical binding]; other site
882884010672	ATP-binding site [chemical binding]; other site
882884010673	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
882884010674	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
882884010675	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
882884010676	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
882884010677	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
882884010678	Zn2+ binding site [ion binding]; other site
882884010679	Mg2+ binding site [ion binding]; other site
882884010680	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
882884010681	synthetase active site [active]
882884010682	NTP binding site [chemical binding]; other site
882884010683	metal binding site [ion binding]; metal-binding site
882884010684	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
882884010685	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
882884010686	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
882884010687	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
882884010688	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
882884010689	catalytic site [active]
882884010690	G-X2-G-X-G-K; other site
882884010691	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
882884010692	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
882884010693	nucleotide binding pocket [chemical binding]; other site
882884010694	K-X-D-G motif; other site
882884010695	catalytic site [active]
882884010696	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
882884010697	Predicted membrane protein [Function unknown]; Region: COG2860
882884010698	UPF0126 domain; Region: UPF0126; pfam03458
882884010699	UPF0126 domain; Region: UPF0126; pfam03458
882884010700	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
882884010701	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884010702	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884010703	dimerization interface [polypeptide binding]; other site
882884010704	LysR substrate binding domain; Region: LysR_substrate; pfam03466
882884010705	hypothetical protein; Provisional; Region: PRK11820
882884010706	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
882884010707	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
882884010708	ribonuclease PH; Reviewed; Region: rph; PRK00173
882884010709	Ribonuclease PH; Region: RNase_PH_bact; cd11362
882884010710	hexamer interface [polypeptide binding]; other site
882884010711	active site
882884010712	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
882884010713	active site
882884010714	division inhibitor protein; Provisional; Region: slmA; PRK09480
882884010715	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884010716	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
882884010717	trimer interface [polypeptide binding]; other site
882884010718	active site
882884010719	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
882884010720	Flavoprotein; Region: Flavoprotein; pfam02441
882884010721	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
882884010722	hypothetical protein; Reviewed; Region: PRK00024
882884010723	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
882884010724	MPN+ (JAMM) motif; other site
882884010725	Zinc-binding site [ion binding]; other site
882884010726	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
882884010727	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
882884010728	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
882884010729	DNA binding site [nucleotide binding]
882884010730	catalytic residue [active]
882884010731	H2TH interface [polypeptide binding]; other site
882884010732	putative catalytic residues [active]
882884010733	turnover-facilitating residue; other site
882884010734	intercalation triad [nucleotide binding]; other site
882884010735	8OG recognition residue [nucleotide binding]; other site
882884010736	putative reading head residues; other site
882884010737	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
882884010738	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
882884010739	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
882884010740	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
882884010741	active site
882884010742	(T/H)XGH motif; other site
882884010743	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
882884010744	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
882884010745	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
882884010746	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
882884010747	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
882884010748	putative active site [active]
882884010749	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
882884010750	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
882884010751	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
882884010752	Glycosyltransferase family 52; Region: Glyco_transf_52; pfam07922
882884010753	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
882884010754	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
882884010755	putative ADP-binding pocket [chemical binding]; other site
882884010756	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
882884010757	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
882884010758	Ligand binding site; other site
882884010759	metal-binding site
882884010760	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
882884010761	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
882884010762	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
882884010763	Ligand binding site; other site
882884010764	metal-binding site
882884010765	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
882884010766	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
882884010767	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
882884010768	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
882884010769	O-antigen ligase RfaL; Provisional; Region: PRK15487
882884010770	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
882884010771	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
882884010772	putative active site [active]
882884010773	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
882884010774	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
882884010775	putative active site [active]
882884010776	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
882884010777	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
882884010778	NADP binding site [chemical binding]; other site
882884010779	homopentamer interface [polypeptide binding]; other site
882884010780	substrate binding site [chemical binding]; other site
882884010781	active site
882884010782	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
882884010783	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
882884010784	substrate-cofactor binding pocket; other site
882884010785	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884010786	catalytic residue [active]
882884010787	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
882884010788	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
882884010789	NAD(P) binding site [chemical binding]; other site
882884010790	putative glycosyl transferase; Provisional; Region: PRK10073
882884010791	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
882884010792	active site
882884010793	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
882884010794	NodB motif; other site
882884010795	putative active site [active]
882884010796	putative catalytic site [active]
882884010797	Zn binding site [ion binding]; other site
882884010798	AmiB activator; Provisional; Region: PRK11637
882884010799	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
882884010800	Peptidase family M23; Region: Peptidase_M23; pfam01551
882884010801	phosphoglyceromutase; Provisional; Region: PRK05434
882884010802	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
882884010803	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
882884010804	active site residue [active]
882884010805	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
882884010806	GSH binding site [chemical binding]; other site
882884010807	catalytic residues [active]
882884010808	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
882884010809	SecA binding site; other site
882884010810	Preprotein binding site; other site
882884010811	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
882884010812	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
882884010813	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
882884010814	serine acetyltransferase; Provisional; Region: cysE; PRK11132
882884010815	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
882884010816	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
882884010817	trimer interface [polypeptide binding]; other site
882884010818	active site
882884010819	substrate binding site [chemical binding]; other site
882884010820	CoA binding site [chemical binding]; other site
882884010821	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884010822	D-galactonate transporter; Region: 2A0114; TIGR00893
882884010823	putative substrate translocation pore; other site
882884010824	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
882884010825	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
882884010826	active site pocket [active]
882884010827	Transcriptional regulators [Transcription]; Region: PurR; COG1609
882884010828	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884010829	DNA binding site [nucleotide binding]
882884010830	domain linker motif; other site
882884010831	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
882884010832	putative dimerization interface [polypeptide binding]; other site
882884010833	putative ligand binding site [chemical binding]; other site
882884010834	putative rRNA methylase; Provisional; Region: PRK10358
882884010835	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
882884010836	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
882884010837	active site
882884010838	substrate binding site [chemical binding]; other site
882884010839	FMN binding site [chemical binding]; other site
882884010840	putative catalytic residues [active]
882884010841	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
882884010842	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884010843	DNA-binding site [nucleotide binding]; DNA binding site
882884010844	FCD domain; Region: FCD; pfam07729
882884010845	L-lactate permease; Provisional; Region: PRK10420
882884010846	glycolate transporter; Provisional; Region: PRK09695
882884010847	hypothetical protein; Provisional; Region: PRK11020
882884010848	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
882884010849	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
882884010850	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
882884010851	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
882884010852	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
882884010853	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
882884010854	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
882884010855	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
882884010856	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
882884010857	active site
882884010858	P-loop; other site
882884010859	phosphorylation site [posttranslational modification]
882884010860	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
882884010861	active site
882884010862	phosphorylation site [posttranslational modification]
882884010863	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
882884010864	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
882884010865	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
882884010866	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
882884010867	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
882884010868	active site turn [active]
882884010869	phosphorylation site [posttranslational modification]
882884010870	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884010871	Sulfatase; Region: Sulfatase; cl17466
882884010872	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
882884010873	active site
882884010874	catalytic residues [active]
882884010875	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
882884010876	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
882884010877	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
882884010878	putative active site [active]
882884010879	Domain of unknown function (DUF202); Region: DUF202; cl09954
882884010880	Domain of unknown function (DUF202); Region: DUF202; pfam02656
882884010881	putative glutathione S-transferase; Provisional; Region: PRK10357
882884010882	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
882884010883	putative C-terminal domain interface [polypeptide binding]; other site
882884010884	putative GSH binding site (G-site) [chemical binding]; other site
882884010885	putative dimer interface [polypeptide binding]; other site
882884010886	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
882884010887	dimer interface [polypeptide binding]; other site
882884010888	N-terminal domain interface [polypeptide binding]; other site
882884010889	putative substrate binding pocket (H-site) [chemical binding]; other site
882884010890	selenocysteine synthase; Provisional; Region: PRK04311
882884010891	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
882884010892	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
882884010893	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
882884010894	catalytic residue [active]
882884010895	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
882884010896	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
882884010897	G1 box; other site
882884010898	putative GEF interaction site [polypeptide binding]; other site
882884010899	GTP/Mg2+ binding site [chemical binding]; other site
882884010900	Switch I region; other site
882884010901	G2 box; other site
882884010902	G3 box; other site
882884010903	Switch II region; other site
882884010904	G4 box; other site
882884010905	G5 box; other site
882884010906	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
882884010907	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
882884010908	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
882884010909	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
882884010910	putative alcohol dehydrogenase; Provisional; Region: PRK09860
882884010911	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
882884010912	dimer interface [polypeptide binding]; other site
882884010913	active site
882884010914	metal binding site [ion binding]; metal-binding site
882884010915	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
882884010916	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
882884010917	nucleotide binding site [chemical binding]; other site
882884010918	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
882884010919	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
882884010920	NAD(P) binding site [chemical binding]; other site
882884010921	catalytic residues [active]
882884010922	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
882884010923	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
882884010924	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
882884010925	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884010926	homodimer interface [polypeptide binding]; other site
882884010927	catalytic residue [active]
882884010928	alpha-amylase; Reviewed; Region: malS; PRK09505
882884010929	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
882884010930	hypothetical protein; Provisional; Region: PRK10356
882884010931	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
882884010932	putative dimerization interface [polypeptide binding]; other site
882884010933	Transcriptional regulators [Transcription]; Region: PurR; COG1609
882884010934	putative ligand binding site [chemical binding]; other site
882884010935	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884010936	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
882884010937	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884010938	xylose isomerase; Provisional; Region: PRK05474
882884010939	xylose isomerase; Region: xylose_isom_A; TIGR02630
882884010940	xylulokinase; Provisional; Region: PRK15027
882884010941	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
882884010942	N- and C-terminal domain interface [polypeptide binding]; other site
882884010943	active site
882884010944	MgATP binding site [chemical binding]; other site
882884010945	catalytic site [active]
882884010946	metal binding site [ion binding]; metal-binding site
882884010947	xylulose binding site [chemical binding]; other site
882884010948	homodimer interface [polypeptide binding]; other site
882884010949	Predicted membrane protein [Function unknown]; Region: COG4682
882884010950	yiaA/B two helix domain; Region: YiaAB; pfam05360
882884010951	yiaA/B two helix domain; Region: YiaAB; cl01759
882884010952	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
882884010953	Acyltransferase family; Region: Acyl_transf_3; pfam01757
882884010954	YsaB-like lipoprotein; Region: YsaB; pfam13983
882884010955	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
882884010956	dimer interface [polypeptide binding]; other site
882884010957	motif 1; other site
882884010958	active site
882884010959	motif 2; other site
882884010960	motif 3; other site
882884010961	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
882884010962	DALR anticodon binding domain; Region: DALR_1; pfam05746
882884010963	Integrase core domain; Region: rve; pfam00665
882884010964	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
882884010965	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
882884010966	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
882884010967	DNA-binding site [nucleotide binding]; DNA binding site
882884010968	RNA-binding motif; other site
882884010969	Predicted transcriptional regulator [Transcription]; Region: COG2944
882884010970	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
882884010971	salt bridge; other site
882884010972	non-specific DNA binding site [nucleotide binding]; other site
882884010973	sequence-specific DNA binding site [nucleotide binding]; other site
882884010974	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
882884010975	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
882884010976	NADP binding site [chemical binding]; other site
882884010977	catalytic site [active]
882884010978	putative outer membrane lipoprotein; Provisional; Region: PRK10510
882884010979	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
882884010980	ligand binding site [chemical binding]; other site
882884010981	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
882884010982	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
882884010983	molybdopterin cofactor binding site [chemical binding]; other site
882884010984	substrate binding site [chemical binding]; other site
882884010985	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
882884010986	molybdopterin cofactor binding site; other site
882884010987	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
882884010988	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884010989	Coenzyme A binding pocket [chemical binding]; other site
882884010990	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
882884010991	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
882884010992	phosphoethanolamine transferase; Provisional; Region: PRK11560
882884010993	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
882884010994	Sulfatase; Region: Sulfatase; pfam00884
882884010995	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
882884010996	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
882884010997	peptide binding site [polypeptide binding]; other site
882884010998	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
882884010999	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884011000	dimer interface [polypeptide binding]; other site
882884011001	conserved gate region; other site
882884011002	putative PBP binding loops; other site
882884011003	ABC-ATPase subunit interface; other site
882884011004	dipeptide transporter; Provisional; Region: PRK10913
882884011005	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
882884011006	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884011007	dimer interface [polypeptide binding]; other site
882884011008	conserved gate region; other site
882884011009	putative PBP binding loops; other site
882884011010	ABC-ATPase subunit interface; other site
882884011011	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
882884011012	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884011013	Walker A/P-loop; other site
882884011014	ATP binding site [chemical binding]; other site
882884011015	Q-loop/lid; other site
882884011016	ABC transporter signature motif; other site
882884011017	Walker B; other site
882884011018	D-loop; other site
882884011019	H-loop/switch region; other site
882884011020	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
882884011021	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
882884011022	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
882884011023	Walker A/P-loop; other site
882884011024	ATP binding site [chemical binding]; other site
882884011025	Q-loop/lid; other site
882884011026	ABC transporter signature motif; other site
882884011027	Walker B; other site
882884011028	D-loop; other site
882884011029	H-loop/switch region; other site
882884011030	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
882884011031	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
882884011032	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
882884011033	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
882884011034	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
882884011035	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
882884011036	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
882884011037	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
882884011038	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
882884011039	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
882884011040	cell division protein; Provisional; Region: PRK10037
882884011041	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
882884011042	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
882884011043	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
882884011044	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
882884011045	DXD motif; other site
882884011046	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
882884011047	PilZ domain; Region: PilZ; pfam07238
882884011048	cellulose synthase regulator protein; Provisional; Region: PRK11114
882884011049	endo-1,4-D-glucanase; Provisional; Region: PRK11097
882884011050	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
882884011051	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
882884011052	TPR motif; other site
882884011053	binding surface
882884011054	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
882884011055	TPR motif; other site
882884011056	binding surface
882884011057	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
882884011058	binding surface
882884011059	TPR motif; other site
882884011060	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
882884011061	putative diguanylate cyclase; Provisional; Region: PRK13561
882884011062	HAMP domain; Region: HAMP; pfam00672
882884011063	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
882884011064	I-site; other site
882884011065	active site
882884011066	metal binding site [ion binding]; metal-binding site
882884011067	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
882884011068	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
882884011069	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
882884011070	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
882884011071	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
882884011072	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
882884011073	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
882884011074	substrate binding site [chemical binding]; other site
882884011075	ATP binding site [chemical binding]; other site
882884011076	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
882884011077	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
882884011078	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
882884011079	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884011080	metabolite-proton symporter; Region: 2A0106; TIGR00883
882884011081	putative substrate translocation pore; other site
882884011082	inner membrane protein YhjD; Region: TIGR00766
882884011083	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884011084	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
882884011085	putative effector binding pocket; other site
882884011086	putative dimerization interface [polypeptide binding]; other site
882884011087	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
882884011088	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884011089	DNA binding residues [nucleotide binding]
882884011090	dimerization interface [polypeptide binding]; other site
882884011091	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
882884011092	catalytic residue [active]
882884011093	trehalase; Provisional; Region: treF; PRK13270
882884011094	Trehalase; Region: Trehalase; pfam01204
882884011095	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
882884011096	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884011097	DNA-binding site [nucleotide binding]; DNA binding site
882884011098	UTRA domain; Region: UTRA; pfam07702
882884011099	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
882884011100	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
882884011101	putative active site [active]
882884011102	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
882884011103	dimer interface [polypeptide binding]; other site
882884011104	active site
882884011105	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
882884011106	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
882884011107	substrate binding site [chemical binding]; other site
882884011108	ATP binding site [chemical binding]; other site
882884011109	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
882884011110	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
882884011111	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
882884011112	active site
882884011113	homodimer interface [polypeptide binding]; other site
882884011114	homotetramer interface [polypeptide binding]; other site
882884011115	glutathione reductase; Validated; Region: PRK06116
882884011116	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
882884011117	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884011118	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
882884011119	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
882884011120	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
882884011121	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
882884011122	active site
882884011123	oligopeptidase A; Provisional; Region: PRK10911
882884011124	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
882884011125	active site
882884011126	Zn binding site [ion binding]; other site
882884011127	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884011128	S-adenosylmethionine binding site [chemical binding]; other site
882884011129	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
882884011130	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
882884011131	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884011132	Predicted transcriptional regulator [Transcription]; Region: COG1959
882884011133	Transcriptional regulator; Region: Rrf2; pfam02082
882884011134	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
882884011135	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884011136	putative substrate translocation pore; other site
882884011137	POT family; Region: PTR2; pfam00854
882884011138	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
882884011139	Ligand Binding Site [chemical binding]; other site
882884011140	universal stress protein UspB; Provisional; Region: PRK04960
882884011141	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
882884011142	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
882884011143	Predicted flavoproteins [General function prediction only]; Region: COG2081
882884011144	nickel responsive regulator; Provisional; Region: PRK02967
882884011145	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
882884011146	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
882884011147	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
882884011148	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
882884011149	Domain of unknown function DUF20; Region: UPF0118; pfam01594
882884011150	hypothetical protein; Provisional; Region: PRK11615
882884011151	hypothetical protein; Provisional; Region: PRK11212
882884011152	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
882884011153	CPxP  motif; other site
882884011154	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
882884011155	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
882884011156	metal-binding site [ion binding]
882884011157	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
882884011158	Predicted membrane protein [Function unknown]; Region: COG3714
882884011159	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
882884011160	hypothetical protein; Provisional; Region: PRK10910
882884011161	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
882884011162	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884011163	S-adenosylmethionine binding site [chemical binding]; other site
882884011164	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
882884011165	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
882884011166	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
882884011167	P loop; other site
882884011168	GTP binding site [chemical binding]; other site
882884011169	cell division protein FtsE; Provisional; Region: PRK10908
882884011170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884011171	Walker A/P-loop; other site
882884011172	ATP binding site [chemical binding]; other site
882884011173	Q-loop/lid; other site
882884011174	ABC transporter signature motif; other site
882884011175	Walker B; other site
882884011176	D-loop; other site
882884011177	H-loop/switch region; other site
882884011178	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
882884011179	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
882884011180	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
882884011181	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
882884011182	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
882884011183	DNA binding residues [nucleotide binding]
882884011184	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
882884011185	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
882884011186	dimerization interface [polypeptide binding]; other site
882884011187	ligand binding site [chemical binding]; other site
882884011188	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
882884011189	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
882884011190	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
882884011191	dimerization interface [polypeptide binding]; other site
882884011192	ligand binding site [chemical binding]; other site
882884011193	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
882884011194	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
882884011195	TM-ABC transporter signature motif; other site
882884011196	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
882884011197	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
882884011198	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
882884011199	TM-ABC transporter signature motif; other site
882884011200	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
882884011201	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
882884011202	Walker A/P-loop; other site
882884011203	ATP binding site [chemical binding]; other site
882884011204	Q-loop/lid; other site
882884011205	ABC transporter signature motif; other site
882884011206	Walker B; other site
882884011207	D-loop; other site
882884011208	H-loop/switch region; other site
882884011209	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
882884011210	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
882884011211	Walker A/P-loop; other site
882884011212	ATP binding site [chemical binding]; other site
882884011213	Q-loop/lid; other site
882884011214	ABC transporter signature motif; other site
882884011215	Walker B; other site
882884011216	D-loop; other site
882884011217	H-loop/switch region; other site
882884011218	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
882884011219	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
882884011220	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
882884011221	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884011222	putative PBP binding loops; other site
882884011223	dimer interface [polypeptide binding]; other site
882884011224	ABC-ATPase subunit interface; other site
882884011225	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
882884011226	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
882884011227	dimer interface [polypeptide binding]; other site
882884011228	conserved gate region; other site
882884011229	ABC-ATPase subunit interface; other site
882884011230	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
882884011231	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
882884011232	Walker A/P-loop; other site
882884011233	ATP binding site [chemical binding]; other site
882884011234	Q-loop/lid; other site
882884011235	ABC transporter signature motif; other site
882884011236	Walker B; other site
882884011237	D-loop; other site
882884011238	H-loop/switch region; other site
882884011239	TOBE domain; Region: TOBE_2; pfam08402
882884011240	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
882884011241	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
882884011242	putative active site [active]
882884011243	catalytic site [active]
882884011244	putative metal binding site [ion binding]; other site
882884011245	hypothetical protein; Provisional; Region: PRK10350
882884011246	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
882884011247	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
882884011248	putative oxidoreductase; Provisional; Region: PRK10206
882884011249	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
882884011250	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
882884011251	Pirin-related protein [General function prediction only]; Region: COG1741
882884011252	Pirin; Region: Pirin; pfam02678
882884011253	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
882884011254	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884011255	DNA binding site [nucleotide binding]
882884011256	domain linker motif; other site
882884011257	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
882884011258	putative ligand binding site [chemical binding]; other site
882884011259	putative dimerization interface [polypeptide binding]; other site
882884011260	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
882884011261	ATP-binding site [chemical binding]; other site
882884011262	Gluconate-6-phosphate binding site [chemical binding]; other site
882884011263	Shikimate kinase; Region: SKI; pfam01202
882884011264	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
882884011265	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
882884011266	glycogen branching enzyme; Provisional; Region: PRK05402
882884011267	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
882884011268	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
882884011269	active site
882884011270	catalytic site [active]
882884011271	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
882884011272	glycogen debranching enzyme; Provisional; Region: PRK03705
882884011273	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
882884011274	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
882884011275	active site
882884011276	catalytic site [active]
882884011277	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
882884011278	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
882884011279	ligand binding site; other site
882884011280	oligomer interface; other site
882884011281	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
882884011282	dimer interface [polypeptide binding]; other site
882884011283	N-terminal domain interface [polypeptide binding]; other site
882884011284	sulfate 1 binding site; other site
882884011285	glycogen synthase; Provisional; Region: glgA; PRK00654
882884011286	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
882884011287	ADP-binding pocket [chemical binding]; other site
882884011288	homodimer interface [polypeptide binding]; other site
882884011289	glycogen phosphorylase; Provisional; Region: PRK14986
882884011290	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
882884011291	homodimer interface [polypeptide binding]; other site
882884011292	active site pocket [active]
882884011293	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
882884011294	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
882884011295	active site residue [active]
882884011296	intramembrane serine protease GlpG; Provisional; Region: PRK10907
882884011297	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
882884011298	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
882884011299	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
882884011300	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
882884011301	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884011302	transcriptional regulator MalT; Provisional; Region: PRK04841
882884011303	AAA ATPase domain; Region: AAA_16; pfam13191
882884011304	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884011305	DNA binding residues [nucleotide binding]
882884011306	dimerization interface [polypeptide binding]; other site
882884011307	maltodextrin phosphorylase; Provisional; Region: PRK14985
882884011308	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
882884011309	homodimer interface [polypeptide binding]; other site
882884011310	active site pocket [active]
882884011311	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
882884011312	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
882884011313	high-affinity gluconate transporter; Provisional; Region: PRK14984
882884011314	gluconate transporter; Region: gntP; TIGR00791
882884011315	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
882884011316	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
882884011317	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
882884011318	DNA utilization protein GntX; Provisional; Region: PRK11595
882884011319	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
882884011320	active site
882884011321	carboxylesterase BioH; Provisional; Region: PRK10349
882884011322	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
882884011323	hypothetical protein; Provisional; Region: PRK09956
882884011324	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
882884011325	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
882884011326	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
882884011327	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
882884011328	G1 box; other site
882884011329	GTP/Mg2+ binding site [chemical binding]; other site
882884011330	Switch I region; other site
882884011331	G2 box; other site
882884011332	G3 box; other site
882884011333	Switch II region; other site
882884011334	G4 box; other site
882884011335	G5 box; other site
882884011336	Nucleoside recognition; Region: Gate; pfam07670
882884011337	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
882884011338	Nucleoside recognition; Region: Gate; pfam07670
882884011339	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
882884011340	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
882884011341	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
882884011342	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
882884011343	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
882884011344	RNA binding site [nucleotide binding]; other site
882884011345	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
882884011346	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
882884011347	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
882884011348	osmolarity response regulator; Provisional; Region: ompR; PRK09468
882884011349	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884011350	active site
882884011351	phosphorylation site [posttranslational modification]
882884011352	intermolecular recognition site; other site
882884011353	dimerization interface [polypeptide binding]; other site
882884011354	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884011355	DNA binding site [nucleotide binding]
882884011356	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
882884011357	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884011358	dimerization interface [polypeptide binding]; other site
882884011359	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884011360	dimer interface [polypeptide binding]; other site
882884011361	phosphorylation site [posttranslational modification]
882884011362	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884011363	ATP binding site [chemical binding]; other site
882884011364	G-X-G motif; other site
882884011365	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
882884011366	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
882884011367	active site
882884011368	substrate-binding site [chemical binding]; other site
882884011369	metal-binding site [ion binding]
882884011370	ATP binding site [chemical binding]; other site
882884011371	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
882884011372	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
882884011373	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
882884011374	dimerization interface [polypeptide binding]; other site
882884011375	domain crossover interface; other site
882884011376	redox-dependent activation switch; other site
882884011377	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
882884011378	RNA binding surface [nucleotide binding]; other site
882884011379	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
882884011380	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884011381	motif II; other site
882884011382	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
882884011383	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
882884011384	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
882884011385	ADP-ribose binding site [chemical binding]; other site
882884011386	dimer interface [polypeptide binding]; other site
882884011387	active site
882884011388	nudix motif; other site
882884011389	metal binding site [ion binding]; metal-binding site
882884011390	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
882884011391	Transglycosylase; Region: Transgly; pfam00912
882884011392	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
882884011393	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
882884011394	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
882884011395	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
882884011396	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
882884011397	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
882884011398	shikimate kinase; Reviewed; Region: aroK; PRK00131
882884011399	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
882884011400	ADP binding site [chemical binding]; other site
882884011401	magnesium binding site [ion binding]; other site
882884011402	putative shikimate binding site; other site
882884011403	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
882884011404	active site
882884011405	dimer interface [polypeptide binding]; other site
882884011406	metal binding site [ion binding]; metal-binding site
882884011407	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
882884011408	cell division protein DamX; Validated; Region: PRK10905
882884011409	DNA adenine methylase; Provisional; Region: PRK10904
882884011410	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
882884011411	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
882884011412	substrate binding site [chemical binding]; other site
882884011413	hexamer interface [polypeptide binding]; other site
882884011414	metal binding site [ion binding]; metal-binding site
882884011415	phosphoglycolate phosphatase; Provisional; Region: PRK13222
882884011416	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
882884011417	motif II; other site
882884011418	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
882884011419	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
882884011420	active site
882884011421	HIGH motif; other site
882884011422	dimer interface [polypeptide binding]; other site
882884011423	KMSKS motif; other site
882884011424	siroheme synthase; Provisional; Region: cysG; PRK10637
882884011425	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
882884011426	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
882884011427	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
882884011428	active site
882884011429	SAM binding site [chemical binding]; other site
882884011430	homodimer interface [polypeptide binding]; other site
882884011431	nitrite transporter NirC; Provisional; Region: PRK11562
882884011432	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
882884011433	nitrite reductase subunit NirD; Provisional; Region: PRK14989
882884011434	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884011435	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
882884011436	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
882884011437	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
882884011438	putative transporter; Provisional; Region: PRK03699
882884011439	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884011440	putative substrate translocation pore; other site
882884011441	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
882884011442	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
882884011443	substrate binding site [chemical binding]; other site
882884011444	hypothetical protein; Provisional; Region: PRK10204
882884011445	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
882884011446	cell filamentation protein Fic; Provisional; Region: PRK10347
882884011447	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
882884011448	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
882884011449	glutamine binding [chemical binding]; other site
882884011450	catalytic triad [active]
882884011451	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
882884011452	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
882884011453	inhibitor-cofactor binding pocket; inhibition site
882884011454	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884011455	catalytic residue [active]
882884011456	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
882884011457	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
882884011458	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
882884011459	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
882884011460	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
882884011461	ligand binding site [chemical binding]; other site
882884011462	flexible hinge region; other site
882884011463	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
882884011464	putative switch regulator; other site
882884011465	non-specific DNA interactions [nucleotide binding]; other site
882884011466	DNA binding site [nucleotide binding]
882884011467	sequence specific DNA binding site [nucleotide binding]; other site
882884011468	putative cAMP binding site [chemical binding]; other site
882884011469	hypothetical protein; Provisional; Region: PRK10738
882884011470	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
882884011471	active site
882884011472	hypothetical protein; Provisional; Region: PRK04966
882884011473	putative hydrolase; Provisional; Region: PRK10985
882884011474	putative monooxygenase; Provisional; Region: PRK11118
882884011475	malonate decarboxylase, alpha subunit; Region: mdcA; TIGR01110
882884011476	Coenzyme A transferase; Region: CoA_trans; cl17247
882884011477	triphosphoribosyl-dephospho-CoA synthase; Validated; Region: PRK01237
882884011478	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189
882884011479	Malonate decarboxylase gamma subunit (MdcE); Region: MdcE; pfam06833
882884011480	he Auxin Efflux Carrier (AEC) Family; Region: 2a69; TIGR00946
882884011481	phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK01293
882884011482	Phosphoribosyl-dephospho-CoA transferase MdcG; Region: MdcG; pfam10620
882884011483	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
882884011484	malonate decarboxylase, epsilon subunit; Region: malonate_mdcH; TIGR03131
882884011485	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884011486	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884011487	The C-terminal substrate-binding domian of LysR-type transcriptional regulator MdcR, which involved in the malonate catabolism contains the type 2 periplasmic binding fold; Region: PBP2_MdcR; cd08416
882884011488	putative dimerization interface [polypeptide binding]; other site
882884011489	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
882884011490	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
882884011491	Walker A/P-loop; other site
882884011492	ATP binding site [chemical binding]; other site
882884011493	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884011494	ABC transporter signature motif; other site
882884011495	Walker B; other site
882884011496	D-loop; other site
882884011497	ABC transporter; Region: ABC_tran_2; pfam12848
882884011498	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
882884011499	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
882884011500	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
882884011501	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
882884011502	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
882884011503	TrkA-N domain; Region: TrkA_N; pfam02254
882884011504	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
882884011505	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
882884011506	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
882884011507	phi X174 lysis protein; Provisional; Region: PRK02793
882884011508	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
882884011509	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
882884011510	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
882884011511	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
882884011512	YheO-like PAS domain; Region: PAS_6; pfam08348
882884011513	HTH domain; Region: HTH_22; pfam13309
882884011514	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
882884011515	sulfur relay protein TusC; Validated; Region: PRK00211
882884011516	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
882884011517	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
882884011518	S17 interaction site [polypeptide binding]; other site
882884011519	S8 interaction site; other site
882884011520	16S rRNA interaction site [nucleotide binding]; other site
882884011521	streptomycin interaction site [chemical binding]; other site
882884011522	23S rRNA interaction site [nucleotide binding]; other site
882884011523	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
882884011524	30S ribosomal protein S7; Validated; Region: PRK05302
882884011525	elongation factor G; Reviewed; Region: PRK00007
882884011526	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
882884011527	G1 box; other site
882884011528	putative GEF interaction site [polypeptide binding]; other site
882884011529	GTP/Mg2+ binding site [chemical binding]; other site
882884011530	Switch I region; other site
882884011531	G2 box; other site
882884011532	G3 box; other site
882884011533	Switch II region; other site
882884011534	G4 box; other site
882884011535	G5 box; other site
882884011536	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
882884011537	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
882884011538	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
882884011539	elongation factor Tu; Reviewed; Region: PRK00049
882884011540	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
882884011541	G1 box; other site
882884011542	GEF interaction site [polypeptide binding]; other site
882884011543	GTP/Mg2+ binding site [chemical binding]; other site
882884011544	Switch I region; other site
882884011545	G2 box; other site
882884011546	G3 box; other site
882884011547	Switch II region; other site
882884011548	G4 box; other site
882884011549	G5 box; other site
882884011550	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
882884011551	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
882884011552	Antibiotic Binding Site [chemical binding]; other site
882884011553	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
882884011554	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
882884011555	heme binding site [chemical binding]; other site
882884011556	ferroxidase pore; other site
882884011557	ferroxidase diiron center [ion binding]; other site
882884011558	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
882884011559	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
882884011560	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
882884011561	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
882884011562	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
882884011563	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
882884011564	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
882884011565	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
882884011566	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
882884011567	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
882884011568	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
882884011569	protein-rRNA interface [nucleotide binding]; other site
882884011570	putative translocon binding site; other site
882884011571	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
882884011572	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
882884011573	G-X-X-G motif; other site
882884011574	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
882884011575	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
882884011576	23S rRNA interface [nucleotide binding]; other site
882884011577	5S rRNA interface [nucleotide binding]; other site
882884011578	putative antibiotic binding site [chemical binding]; other site
882884011579	L25 interface [polypeptide binding]; other site
882884011580	L27 interface [polypeptide binding]; other site
882884011581	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
882884011582	23S rRNA interface [nucleotide binding]; other site
882884011583	putative translocon interaction site; other site
882884011584	signal recognition particle (SRP54) interaction site; other site
882884011585	L23 interface [polypeptide binding]; other site
882884011586	trigger factor interaction site; other site
882884011587	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
882884011588	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
882884011589	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
882884011590	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
882884011591	RNA binding site [nucleotide binding]; other site
882884011592	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
882884011593	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
882884011594	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
882884011595	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
882884011596	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
882884011597	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
882884011598	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
882884011599	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
882884011600	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
882884011601	23S rRNA interface [nucleotide binding]; other site
882884011602	5S rRNA interface [nucleotide binding]; other site
882884011603	L27 interface [polypeptide binding]; other site
882884011604	L5 interface [polypeptide binding]; other site
882884011605	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
882884011606	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
882884011607	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
882884011608	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
882884011609	23S rRNA binding site [nucleotide binding]; other site
882884011610	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
882884011611	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
882884011612	SecY translocase; Region: SecY; pfam00344
882884011613	alpha operon ribosome binding site
882884011614	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
882884011615	30S ribosomal protein S13; Region: bact_S13; TIGR03631
882884011616	30S ribosomal protein S11; Validated; Region: PRK05309
882884011617	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
882884011618	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
882884011619	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
882884011620	RNA binding surface [nucleotide binding]; other site
882884011621	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
882884011622	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
882884011623	alphaNTD homodimer interface [polypeptide binding]; other site
882884011624	alphaNTD - beta interaction site [polypeptide binding]; other site
882884011625	alphaNTD - beta' interaction site [polypeptide binding]; other site
882884011626	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
882884011627	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
882884011628	hypothetical protein; Provisional; Region: PRK10203
882884011629	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
882884011630	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
882884011631	DNA binding residues [nucleotide binding]
882884011632	dimer interface [polypeptide binding]; other site
882884011633	metal binding site [ion binding]; metal-binding site
882884011634	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
882884011635	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
882884011636	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
882884011637	TrkA-N domain; Region: TrkA_N; pfam02254
882884011638	TrkA-C domain; Region: TrkA_C; pfam02080
882884011639	TrkA-N domain; Region: TrkA_N; pfam02254
882884011640	TrkA-C domain; Region: TrkA_C; pfam02080
882884011641	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
882884011642	putative RNA binding site [nucleotide binding]; other site
882884011643	16S rRNA methyltransferase B; Provisional; Region: PRK10901
882884011644	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884011645	S-adenosylmethionine binding site [chemical binding]; other site
882884011646	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
882884011647	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
882884011648	putative active site [active]
882884011649	substrate binding site [chemical binding]; other site
882884011650	putative cosubstrate binding site; other site
882884011651	catalytic site [active]
882884011652	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
882884011653	substrate binding site [chemical binding]; other site
882884011654	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
882884011655	active site
882884011656	catalytic residues [active]
882884011657	metal binding site [ion binding]; metal-binding site
882884011658	hypothetical protein; Provisional; Region: PRK10736
882884011659	DNA protecting protein DprA; Region: dprA; TIGR00732
882884011660	hypothetical protein; Validated; Region: PRK03430
882884011661	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
882884011662	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
882884011663	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
882884011664	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
882884011665	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
882884011666	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
882884011667	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
882884011668	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
882884011669	shikimate binding site; other site
882884011670	NAD(P) binding site [chemical binding]; other site
882884011671	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
882884011672	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
882884011673	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
882884011674	trimer interface [polypeptide binding]; other site
882884011675	putative metal binding site [ion binding]; other site
882884011676	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
882884011677	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
882884011678	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
882884011679	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884011680	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
882884011681	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
882884011682	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
882884011683	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
882884011684	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
882884011685	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
882884011686	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
882884011687	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884011688	DNA methylase; Region: N6_N4_Mtase; pfam01555
882884011689	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
882884011690	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
882884011691	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
882884011692	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
882884011693	FMN binding site [chemical binding]; other site
882884011694	active site
882884011695	catalytic residues [active]
882884011696	substrate binding site [chemical binding]; other site
882884011697	Carbonic anhydrase alpha, prokaryotic-like subfamily. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon...; Region: alpha_CA_prokaryotic_like; cd03124
882884011698	active site
882884011699	zinc binding site [ion binding]; other site
882884011700	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
882884011701	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
882884011702	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
882884011703	Na binding site [ion binding]; other site
882884011704	hypothetical protein; Provisional; Region: PRK10633
882884011705	Peptidase M60-like family; Region: M60-like; pfam13402
882884011706	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
882884011707	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
882884011708	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
882884011709	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
882884011710	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
882884011711	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
882884011712	carboxyltransferase (CT) interaction site; other site
882884011713	biotinylation site [posttranslational modification]; other site
882884011714	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
882884011715	TMAO/DMSO reductase; Reviewed; Region: PRK05363
882884011716	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
882884011717	Moco binding site; other site
882884011718	metal coordination site [ion binding]; other site
882884011719	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
882884011720	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
882884011721	NADP binding site [chemical binding]; other site
882884011722	dimer interface [polypeptide binding]; other site
882884011723	regulatory protein CsrD; Provisional; Region: PRK11059
882884011724	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
882884011725	metal binding site [ion binding]; metal-binding site
882884011726	active site
882884011727	I-site; other site
882884011728	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
882884011729	rod shape-determining protein MreB; Provisional; Region: PRK13927
882884011730	MreB and similar proteins; Region: MreB_like; cd10225
882884011731	nucleotide binding site [chemical binding]; other site
882884011732	Mg binding site [ion binding]; other site
882884011733	putative protofilament interaction site [polypeptide binding]; other site
882884011734	RodZ interaction site [polypeptide binding]; other site
882884011735	rod shape-determining protein MreC; Region: mreC; TIGR00219
882884011736	rod shape-determining protein MreC; Region: MreC; pfam04085
882884011737	rod shape-determining protein MreD; Provisional; Region: PRK11060
882884011738	Maf-like protein; Region: Maf; pfam02545
882884011739	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
882884011740	active site
882884011741	dimer interface [polypeptide binding]; other site
882884011742	ribonuclease G; Provisional; Region: PRK11712
882884011743	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
882884011744	homodimer interface [polypeptide binding]; other site
882884011745	oligonucleotide binding site [chemical binding]; other site
882884011746	hypothetical protein; Provisional; Region: PRK10899
882884011747	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
882884011748	protease TldD; Provisional; Region: tldD; PRK10735
882884011749	transcriptional regulator; Provisional; Region: PRK10632
882884011750	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884011751	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
882884011752	putative effector binding pocket; other site
882884011753	dimerization interface [polypeptide binding]; other site
882884011754	efflux system membrane protein; Provisional; Region: PRK11594
882884011755	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
882884011756	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
882884011757	HlyD family secretion protein; Region: HlyD_3; pfam13437
882884011758	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
882884011759	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
882884011760	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
882884011761	RNAase interaction site [polypeptide binding]; other site
882884011762	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884011763	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
882884011764	arginine repressor; Provisional; Region: PRK05066
882884011765	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
882884011766	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
882884011767	malate dehydrogenase; Provisional; Region: PRK05086
882884011768	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
882884011769	NAD binding site [chemical binding]; other site
882884011770	dimerization interface [polypeptide binding]; other site
882884011771	Substrate binding site [chemical binding]; other site
882884011772	serine endoprotease; Provisional; Region: PRK10898
882884011773	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
882884011774	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
882884011775	serine endoprotease; Provisional; Region: PRK10139
882884011776	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
882884011777	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
882884011778	protein binding site [polypeptide binding]; other site
882884011779	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
882884011780	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
882884011781	hypothetical protein; Provisional; Region: PRK11677
882884011782	Predicted ATPase [General function prediction only]; Region: COG1485
882884011783	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
882884011784	23S rRNA interface [nucleotide binding]; other site
882884011785	L3 interface [polypeptide binding]; other site
882884011786	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
882884011787	stringent starvation protein A; Provisional; Region: sspA; PRK09481
882884011788	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
882884011789	C-terminal domain interface [polypeptide binding]; other site
882884011790	putative GSH binding site (G-site) [chemical binding]; other site
882884011791	dimer interface [polypeptide binding]; other site
882884011792	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
882884011793	dimer interface [polypeptide binding]; other site
882884011794	N-terminal domain interface [polypeptide binding]; other site
882884011795	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
882884011796	transcriptional regulator NanR; Provisional; Region: PRK03837
882884011797	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
882884011798	DNA-binding site [nucleotide binding]; DNA binding site
882884011799	FCD domain; Region: FCD; pfam07729
882884011800	N-acetylneuraminate lyase; Provisional; Region: PRK04147
882884011801	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
882884011802	inhibitor site; inhibition site
882884011803	active site
882884011804	dimer interface [polypeptide binding]; other site
882884011805	catalytic residue [active]
882884011806	putative sialic acid transporter; Provisional; Region: PRK03893
882884011807	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884011808	putative substrate translocation pore; other site
882884011809	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
882884011810	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
882884011811	putative active site cavity [active]
882884011812	N-acetylmannosamine kinase; Provisional; Region: PRK05082
882884011813	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
882884011814	nucleotide binding site [chemical binding]; other site
882884011815	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
882884011816	cytosine deaminase; Provisional; Region: PRK09230
882884011817	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
882884011818	active site
882884011819	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
882884011820	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
882884011821	Na binding site [ion binding]; other site
882884011822	putative substrate binding site [chemical binding]; other site
882884011823	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
882884011824	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
882884011825	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
882884011826	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
882884011827	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
882884011828	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
882884011829	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
882884011830	active site
882884011831	dimer interface [polypeptide binding]; other site
882884011832	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
882884011833	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
882884011834	active site
882884011835	FMN binding site [chemical binding]; other site
882884011836	substrate binding site [chemical binding]; other site
882884011837	3Fe-4S cluster binding site [ion binding]; other site
882884011838	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
882884011839	domain interface; other site
882884011840	radical SAM protein, TIGR01212 family; Region: TIGR01212
882884011841	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884011842	FeS/SAM binding site; other site
882884011843	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
882884011844	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
882884011845	putative active site [active]
882884011846	heme pocket [chemical binding]; other site
882884011847	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884011848	dimer interface [polypeptide binding]; other site
882884011849	phosphorylation site [posttranslational modification]
882884011850	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884011851	ATP binding site [chemical binding]; other site
882884011852	Mg2+ binding site [ion binding]; other site
882884011853	G-X-G motif; other site
882884011854	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884011855	active site
882884011856	phosphorylation site [posttranslational modification]
882884011857	intermolecular recognition site; other site
882884011858	dimerization interface [polypeptide binding]; other site
882884011859	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
882884011860	putative binding surface; other site
882884011861	active site
882884011862	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
882884011863	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
882884011864	conserved cys residue [active]
882884011865	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
882884011866	Transglycosylase; Region: Transgly; cl17702
882884011867	hypothetical protein; Provisional; Region: PRK10345
882884011868	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
882884011869	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
882884011870	dimerization domain swap beta strand [polypeptide binding]; other site
882884011871	regulatory protein interface [polypeptide binding]; other site
882884011872	active site
882884011873	regulatory phosphorylation site [posttranslational modification]; other site
882884011874	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
882884011875	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
882884011876	active site
882884011877	phosphorylation site [posttranslational modification]
882884011878	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
882884011879	30S subunit binding site; other site
882884011880	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
882884011881	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
882884011882	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
882884011883	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
882884011884	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
882884011885	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
882884011886	Walker A/P-loop; other site
882884011887	ATP binding site [chemical binding]; other site
882884011888	Q-loop/lid; other site
882884011889	ABC transporter signature motif; other site
882884011890	Walker B; other site
882884011891	D-loop; other site
882884011892	H-loop/switch region; other site
882884011893	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
882884011894	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
882884011895	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
882884011896	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
882884011897	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
882884011898	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
882884011899	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
882884011900	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
882884011901	putative active site [active]
882884011902	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
882884011903	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
882884011904	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
882884011905	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
882884011906	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
882884011907	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
882884011908	Walker A/P-loop; other site
882884011909	ATP binding site [chemical binding]; other site
882884011910	Q-loop/lid; other site
882884011911	ABC transporter signature motif; other site
882884011912	Walker B; other site
882884011913	D-loop; other site
882884011914	H-loop/switch region; other site
882884011915	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
882884011916	conserved hypothetical integral membrane protein; Region: TIGR00056
882884011917	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
882884011918	mce related protein; Region: MCE; pfam02470
882884011919	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
882884011920	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
882884011921	anti sigma factor interaction site; other site
882884011922	regulatory phosphorylation site [posttranslational modification]; other site
882884011923	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
882884011924	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
882884011925	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
882884011926	hinge; other site
882884011927	active site
882884011928	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
882884011929	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
882884011930	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
882884011931	substrate binding pocket [chemical binding]; other site
882884011932	chain length determination region; other site
882884011933	substrate-Mg2+ binding site; other site
882884011934	catalytic residues [active]
882884011935	aspartate-rich region 1; other site
882884011936	active site lid residues [active]
882884011937	aspartate-rich region 2; other site
882884011938	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
882884011939	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
882884011940	EamA-like transporter family; Region: EamA; pfam00892
882884011941	EamA-like transporter family; Region: EamA; pfam00892
882884011942	GTPase CgtA; Reviewed; Region: obgE; PRK12298
882884011943	GTP1/OBG; Region: GTP1_OBG; pfam01018
882884011944	Obg GTPase; Region: Obg; cd01898
882884011945	G1 box; other site
882884011946	GTP/Mg2+ binding site [chemical binding]; other site
882884011947	Switch I region; other site
882884011948	G2 box; other site
882884011949	G3 box; other site
882884011950	Switch II region; other site
882884011951	G4 box; other site
882884011952	G5 box; other site
882884011953	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
882884011954	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
882884011955	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
882884011956	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
882884011957	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
882884011958	RNA-binding protein YhbY; Provisional; Region: PRK10343
882884011959	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
882884011960	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884011961	S-adenosylmethionine binding site [chemical binding]; other site
882884011962	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
882884011963	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
882884011964	Walker A motif; other site
882884011965	ATP binding site [chemical binding]; other site
882884011966	Walker B motif; other site
882884011967	arginine finger; other site
882884011968	Peptidase family M41; Region: Peptidase_M41; pfam01434
882884011969	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
882884011970	dihydropteroate synthase; Region: DHPS; TIGR01496
882884011971	substrate binding pocket [chemical binding]; other site
882884011972	dimer interface [polypeptide binding]; other site
882884011973	inhibitor binding site; inhibition site
882884011974	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
882884011975	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
882884011976	active site
882884011977	substrate binding site [chemical binding]; other site
882884011978	metal binding site [ion binding]; metal-binding site
882884011979	Preprotein translocase SecG subunit; Region: SecG; pfam03840
882884011980	argininosuccinate synthase; Validated; Region: PRK05370
882884011981	ribosome maturation protein RimP; Reviewed; Region: PRK00092
882884011982	Sm and related proteins; Region: Sm_like; cl00259
882884011983	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
882884011984	putative oligomer interface [polypeptide binding]; other site
882884011985	putative RNA binding site [nucleotide binding]; other site
882884011986	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
882884011987	NusA N-terminal domain; Region: NusA_N; pfam08529
882884011988	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
882884011989	RNA binding site [nucleotide binding]; other site
882884011990	homodimer interface [polypeptide binding]; other site
882884011991	NusA-like KH domain; Region: KH_5; pfam13184
882884011992	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
882884011993	G-X-X-G motif; other site
882884011994	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
882884011995	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
882884011996	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
882884011997	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
882884011998	translation initiation factor IF-2; Region: IF-2; TIGR00487
882884011999	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
882884012000	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
882884012001	G1 box; other site
882884012002	putative GEF interaction site [polypeptide binding]; other site
882884012003	GTP/Mg2+ binding site [chemical binding]; other site
882884012004	Switch I region; other site
882884012005	G2 box; other site
882884012006	G3 box; other site
882884012007	Switch II region; other site
882884012008	G4 box; other site
882884012009	G5 box; other site
882884012010	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
882884012011	Translation-initiation factor 2; Region: IF-2; pfam11987
882884012012	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
882884012013	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
882884012014	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
882884012015	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
882884012016	RNA binding site [nucleotide binding]; other site
882884012017	active site
882884012018	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
882884012019	ribosomal s15 leader
882884012020	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
882884012021	16S/18S rRNA binding site [nucleotide binding]; other site
882884012022	S13e-L30e interaction site [polypeptide binding]; other site
882884012023	25S rRNA binding site [nucleotide binding]; other site
882884012024	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
882884012025	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
882884012026	RNase E interface [polypeptide binding]; other site
882884012027	trimer interface [polypeptide binding]; other site
882884012028	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
882884012029	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
882884012030	RNase E interface [polypeptide binding]; other site
882884012031	trimer interface [polypeptide binding]; other site
882884012032	active site
882884012033	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
882884012034	putative nucleic acid binding region [nucleotide binding]; other site
882884012035	G-X-X-G motif; other site
882884012036	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
882884012037	RNA binding site [nucleotide binding]; other site
882884012038	domain interface; other site
882884012039	lipoprotein NlpI; Provisional; Region: PRK11189
882884012040	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
882884012041	binding surface
882884012042	TPR motif; other site
882884012043	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
882884012044	DEAD-like helicases superfamily; Region: DEXDc; smart00487
882884012045	ATP binding site [chemical binding]; other site
882884012046	Mg++ binding site [ion binding]; other site
882884012047	motif III; other site
882884012048	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
882884012049	nucleotide binding region [chemical binding]; other site
882884012050	ATP-binding site [chemical binding]; other site
882884012051	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
882884012052	putative RNA binding site [nucleotide binding]; other site
882884012053	tryptophan permease; Provisional; Region: PRK10483
882884012054	aromatic amino acid transport protein; Region: araaP; TIGR00837
882884012055	hypothetical protein; Provisional; Region: PRK10508
882884012056	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
882884012057	putative protease; Provisional; Region: PRK15447
882884012058	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
882884012059	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
882884012060	Peptidase family U32; Region: Peptidase_U32; pfam01136
882884012061	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
882884012062	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884012063	Coenzyme A binding pocket [chemical binding]; other site
882884012064	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
882884012065	GIY-YIG motif/motif A; other site
882884012066	putative active site [active]
882884012067	putative metal binding site [ion binding]; other site
882884012068	hypothetical protein; Provisional; Region: PRK03467
882884012069	intracellular protease, PfpI family; Region: PfpI; TIGR01382
882884012070	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
882884012071	proposed catalytic triad [active]
882884012072	conserved cys residue [active]
882884012073	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
882884012074	NADH(P)-binding; Region: NAD_binding_10; pfam13460
882884012075	NAD binding site [chemical binding]; other site
882884012076	active site
882884012077	outer membrane lipoprotein; Provisional; Region: PRK11023
882884012078	BON domain; Region: BON; pfam04972
882884012079	BON domain; Region: BON; pfam04972
882884012080	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
882884012081	dimer interface [polypeptide binding]; other site
882884012082	active site
882884012083	TIGR00252 family protein; Region: TIGR00252
882884012084	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
882884012085	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
882884012086	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
882884012087	putative ligand binding site [chemical binding]; other site
882884012088	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
882884012089	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
882884012090	putative SAM binding site [chemical binding]; other site
882884012091	putative homodimer interface [polypeptide binding]; other site
882884012092	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
882884012093	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
882884012094	intersubunit interface [polypeptide binding]; other site
882884012095	active site
882884012096	zinc binding site [ion binding]; other site
882884012097	Na+ binding site [ion binding]; other site
882884012098	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
882884012099	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
882884012100	dimer interface [polypeptide binding]; other site
882884012101	active site
882884012102	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
882884012103	putative active site [active]
882884012104	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
882884012105	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
882884012106	active site
882884012107	dimer interface [polypeptide binding]; other site
882884012108	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
882884012109	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
882884012110	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
882884012111	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884012112	galactarate dehydratase; Region: galactar-dH20; TIGR03248
882884012113	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
882884012114	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
882884012115	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
882884012116	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
882884012117	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
882884012118	glycerate kinase I; Provisional; Region: PRK10342
882884012119	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
882884012120	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884012121	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
882884012122	putative substrate binding pocket [chemical binding]; other site
882884012123	putative dimerization interface [polypeptide binding]; other site
882884012124	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
882884012125	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
882884012126	tetramer interface [polypeptide binding]; other site
882884012127	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884012128	catalytic residue [active]
882884012129	threonine/serine transporter TdcC; Provisional; Region: PRK13629
882884012130	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
882884012131	propionate/acetate kinase; Provisional; Region: PRK12379
882884012132	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
882884012133	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
882884012134	Pyruvate formate lyase 1; Region: PFL1; cd01678
882884012135	coenzyme A binding site [chemical binding]; other site
882884012136	active site
882884012137	catalytic residues [active]
882884012138	glycine loop; other site
882884012139	L-serine dehydratase TdcG; Provisional; Region: PRK15040
882884012140	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
882884012141	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
882884012142	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
882884012143	serine transporter; Region: stp; TIGR00814
882884012144	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
882884012145	Pirin-related protein [General function prediction only]; Region: COG1741
882884012146	Pirin; Region: Pirin; pfam02678
882884012147	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884012148	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
882884012149	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884012150	dimerization interface [polypeptide binding]; other site
882884012151	Predicted membrane protein [Function unknown]; Region: COG3152
882884012152	Transposase; Region: HTH_Tnp_1; pfam01527
882884012153	insertion element IS2 transposase InsD; Provisional; Region: PRK14702
882884012154	HTH-like domain; Region: HTH_21; pfam13276
882884012155	Integrase core domain; Region: rve; pfam00665
882884012156	Integrase core domain; Region: rve_3; pfam13683
882884012157	Protein of unknown function (DUF3380); Region: DUF3380; pfam11860
882884012158	Integrase core domain; Region: rve; pfam00665
882884012159	DDE domain; Region: DDE_Tnp_IS240; pfam13610
882884012160	Integrase core domain; Region: rve_2; pfam13333
882884012161	HTH-like domain; Region: HTH_21; pfam13276
882884012162	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884012163	Transposase; Region: HTH_Tnp_1; pfam01527
882884012164	Predicted membrane protein [Function unknown]; Region: COG2259
882884012165	YqjK-like protein; Region: YqjK; pfam13997
882884012166	Predicted membrane protein [Function unknown]; Region: COG5393
882884012167	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
882884012168	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
882884012169	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
882884012170	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
882884012171	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
882884012172	serine/threonine transporter SstT; Provisional; Region: PRK13628
882884012173	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
882884012174	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
882884012175	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
882884012176	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
882884012177	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
882884012178	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
882884012179	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
882884012180	S-adenosylmethionine binding site [chemical binding]; other site
882884012181	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
882884012182	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
882884012183	active site
882884012184	FMN binding site [chemical binding]; other site
882884012185	2,4-decadienoyl-CoA binding site; other site
882884012186	catalytic residue [active]
882884012187	4Fe-4S cluster binding site [ion binding]; other site
882884012188	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
882884012189	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
882884012190	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
882884012191	inhibitor-cofactor binding pocket; inhibition site
882884012192	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884012193	catalytic residue [active]
882884012194	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
882884012195	PAS fold; Region: PAS_3; pfam08447
882884012196	putative active site [active]
882884012197	heme pocket [chemical binding]; other site
882884012198	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
882884012199	HAMP domain; Region: HAMP; pfam00672
882884012200	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
882884012201	dimer interface [polypeptide binding]; other site
882884012202	putative CheW interface [polypeptide binding]; other site
882884012203	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
882884012204	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884012205	dimerization interface [polypeptide binding]; other site
882884012206	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
882884012207	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
882884012208	dimer interface [polypeptide binding]; other site
882884012209	putative CheW interface [polypeptide binding]; other site
882884012210	Predicted transcriptional regulators [Transcription]; Region: COG1695
882884012211	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
882884012212	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
882884012213	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
882884012214	FAD binding pocket [chemical binding]; other site
882884012215	FAD binding motif [chemical binding]; other site
882884012216	phosphate binding motif [ion binding]; other site
882884012217	NAD binding pocket [chemical binding]; other site
882884012218	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
882884012219	active site
882884012220	SUMO-1 interface [polypeptide binding]; other site
882884012221	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
882884012222	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
882884012223	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
882884012224	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
882884012225	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
882884012226	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
882884012227	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
882884012228	DNA binding residues [nucleotide binding]
882884012229	DNA primase; Validated; Region: dnaG; PRK05667
882884012230	CHC2 zinc finger; Region: zf-CHC2; pfam01807
882884012231	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
882884012232	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
882884012233	active site
882884012234	metal binding site [ion binding]; metal-binding site
882884012235	interdomain interaction site; other site
882884012236	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
882884012237	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
882884012238	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
882884012239	UGMP family protein; Validated; Region: PRK09604
882884012240	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
882884012241	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
882884012242	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
882884012243	homooctamer interface [polypeptide binding]; other site
882884012244	active site
882884012245	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
882884012246	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
882884012247	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
882884012248	active site
882884012249	NTP binding site [chemical binding]; other site
882884012250	metal binding triad [ion binding]; metal-binding site
882884012251	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
882884012252	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
882884012253	Zn2+ binding site [ion binding]; other site
882884012254	Mg2+ binding site [ion binding]; other site
882884012255	SH3 domain-containing protein; Provisional; Region: PRK10884
882884012256	Bacterial SH3 domain homologues; Region: SH3b; smart00287
882884012257	Uncharacterized conserved protein [Function unknown]; Region: COG3025
882884012258	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
882884012259	putative active site [active]
882884012260	putative metal binding residues [ion binding]; other site
882884012261	signature motif; other site
882884012262	putative triphosphate binding site [ion binding]; other site
882884012263	CHAD domain; Region: CHAD; pfam05235
882884012264	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
882884012265	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
882884012266	metal binding triad; other site
882884012267	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
882884012268	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
882884012269	metal binding triad; other site
882884012270	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
882884012271	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
882884012272	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
882884012273	putative ribose interaction site [chemical binding]; other site
882884012274	putative ADP binding site [chemical binding]; other site
882884012275	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
882884012276	active site
882884012277	nucleotide binding site [chemical binding]; other site
882884012278	HIGH motif; other site
882884012279	KMSKS motif; other site
882884012280	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
882884012281	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
882884012282	FMN riboswitch (RFN element)
882884012283	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
882884012284	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
882884012285	putative disulfide oxidoreductase; Provisional; Region: PRK04307
882884012286	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
882884012287	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
882884012288	catalytic residues [active]
882884012289	hinge region; other site
882884012290	alpha helical domain; other site
882884012291	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
882884012292	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
882884012293	zinc transporter ZupT; Provisional; Region: PRK04201
882884012294	ZIP Zinc transporter; Region: Zip; pfam02535
882884012295	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
882884012296	hypothetical protein; Provisional; Region: PRK11653
882884012297	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
882884012298	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
882884012299	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
882884012300	dimer interface [polypeptide binding]; other site
882884012301	ADP-ribose binding site [chemical binding]; other site
882884012302	active site
882884012303	nudix motif; other site
882884012304	metal binding site [ion binding]; metal-binding site
882884012305	putative dehydrogenase; Provisional; Region: PRK11039
882884012306	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
882884012307	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
882884012308	active site
882884012309	metal binding site [ion binding]; metal-binding site
882884012310	hexamer interface [polypeptide binding]; other site
882884012311	esterase YqiA; Provisional; Region: PRK11071
882884012312	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
882884012313	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884012314	ATP binding site [chemical binding]; other site
882884012315	Mg2+ binding site [ion binding]; other site
882884012316	G-X-G motif; other site
882884012317	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
882884012318	anchoring element; other site
882884012319	dimer interface [polypeptide binding]; other site
882884012320	ATP binding site [chemical binding]; other site
882884012321	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
882884012322	active site
882884012323	metal binding site [ion binding]; metal-binding site
882884012324	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
882884012325	Uncharacterized conserved protein [Function unknown]; Region: COG1359
882884012326	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
882884012327	sensor protein QseC; Provisional; Region: PRK10337
882884012328	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
882884012329	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
882884012330	dimer interface [polypeptide binding]; other site
882884012331	phosphorylation site [posttranslational modification]
882884012332	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
882884012333	ATP binding site [chemical binding]; other site
882884012334	Mg2+ binding site [ion binding]; other site
882884012335	G-X-G motif; other site
882884012336	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
882884012337	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
882884012338	active site
882884012339	phosphorylation site [posttranslational modification]
882884012340	intermolecular recognition site; other site
882884012341	dimerization interface [polypeptide binding]; other site
882884012342	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
882884012343	DNA binding site [nucleotide binding]
882884012344	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
882884012345	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
882884012346	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
882884012347	CAP-like domain; other site
882884012348	active site
882884012349	primary dimer interface [polypeptide binding]; other site
882884012350	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
882884012351	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
882884012352	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
882884012353	putative acyl-acceptor binding pocket; other site
882884012354	FtsI repressor; Provisional; Region: PRK10883
882884012355	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
882884012356	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
882884012357	hypothetical protein; Provisional; Region: PRK01254
882884012358	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
882884012359	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
882884012360	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
882884012361	nucleotide binding site/active site [active]
882884012362	HIT family signature motif; other site
882884012363	catalytic residue [active]
882884012364	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
882884012365	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
882884012366	transmembrane helices; other site
882884012367	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
882884012368	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
882884012369	active site
882884012370	catalytic tetrad [active]
882884012371	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
882884012372	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
882884012373	dimer interface [polypeptide binding]; other site
882884012374	active site
882884012375	metal binding site [ion binding]; metal-binding site
882884012376	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
882884012377	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
882884012378	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884012379	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884012380	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
882884012381	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
882884012382	cystathionine beta-lyase; Provisional; Region: PRK08114
882884012383	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
882884012384	homodimer interface [polypeptide binding]; other site
882884012385	substrate-cofactor binding pocket; other site
882884012386	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884012387	catalytic residue [active]
882884012388	biopolymer transport protein ExbB; Provisional; Region: PRK10414
882884012389	biopolymer transport protein ExbD; Provisional; Region: PRK11267
882884012390	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
882884012391	oxidoreductase; Provisional; Region: PRK07985
882884012392	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
882884012393	NAD binding site [chemical binding]; other site
882884012394	metal binding site [ion binding]; metal-binding site
882884012395	active site
882884012396	Uncharacterized protein family, UPF0114; Region: UPF0114; cl01078
882884012397	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
882884012398	dimerization interface [polypeptide binding]; other site
882884012399	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
882884012400	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
882884012401	dimer interface [polypeptide binding]; other site
882884012402	putative CheW interface [polypeptide binding]; other site
882884012403	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
882884012404	hydrogenase 2 small subunit; Provisional; Region: PRK10468
882884012405	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
882884012406	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
882884012407	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
882884012408	4Fe-4S binding domain; Region: Fer4_6; pfam12837
882884012409	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
882884012410	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
882884012411	hydrogenase 2 large subunit; Provisional; Region: PRK10467
882884012412	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
882884012413	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
882884012414	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
882884012415	putative substrate-binding site; other site
882884012416	nickel binding site [ion binding]; other site
882884012417	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
882884012418	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
882884012419	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
882884012420	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
882884012421	putative S-transferase; Provisional; Region: PRK11752
882884012422	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
882884012423	C-terminal domain interface [polypeptide binding]; other site
882884012424	GSH binding site (G-site) [chemical binding]; other site
882884012425	dimer interface [polypeptide binding]; other site
882884012426	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
882884012427	dimer interface [polypeptide binding]; other site
882884012428	N-terminal domain interface [polypeptide binding]; other site
882884012429	active site
882884012430	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
882884012431	CHAP domain; Region: CHAP; pfam05257
882884012432	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
882884012433	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
882884012434	dimer interface [polypeptide binding]; other site
882884012435	putative CheW interface [polypeptide binding]; other site
882884012436	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
882884012437	Glucuronate isomerase; Region: UxaC; pfam02614
882884012438	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
882884012439	D-mannonate oxidoreductase; Provisional; Region: PRK15037
882884012440	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
882884012441	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
882884012442	mannonate dehydratase; Provisional; Region: PRK03906
882884012443	mannonate dehydratase; Region: uxuA; TIGR00695
882884012444	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884012445	D-galactonate transporter; Region: 2A0114; TIGR00893
882884012446	putative substrate translocation pore; other site
882884012447	Predicted amidohydrolase [General function prediction only]; Region: COG0388
882884012448	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
882884012449	putative active site [active]
882884012450	catalytic triad [active]
882884012451	putative dimer interface [polypeptide binding]; other site
882884012452	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
882884012453	active site
882884012454	catalytic site [active]
882884012455	Zn binding site [ion binding]; other site
882884012456	tetramer interface [polypeptide binding]; other site
882884012457	Protein of unknown function (DUF796); Region: DUF796; cl01226
882884012458	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
882884012459	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
882884012460	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
882884012461	NAD(P) binding site [chemical binding]; other site
882884012462	catalytic residues [active]
882884012463	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
882884012464	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
882884012465	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
882884012466	Amino acid permease; Region: AA_permease_2; pfam13520
882884012467	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
882884012468	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
882884012469	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
882884012470	DNA binding residues [nucleotide binding]
882884012471	dimerization interface [polypeptide binding]; other site
882884012472	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
882884012473	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884012474	FeS/SAM binding site; other site
882884012475	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
882884012476	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
882884012477	Sulfatase; Region: Sulfatase; pfam00884
882884012478	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
882884012479	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884012480	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
882884012481	putative dimerization interface [polypeptide binding]; other site
882884012482	putative substrate binding pocket [chemical binding]; other site
882884012483	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
882884012484	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
882884012485	putative active site [active]
882884012486	putative catalytic site [active]
882884012487	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
882884012488	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
882884012489	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
882884012490	RHS Repeat; Region: RHS_repeat; cl11982
882884012491	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884012492	Transposase; Region: HTH_Tnp_1; cl17663
882884012493	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
882884012494	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
882884012495	PemK-like protein; Region: PemK; cl00995
882884012496	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
882884012497	Integrase; Region: Integrase_1; pfam12835
882884012498	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884012499	active site
882884012500	Int/Topo IB signature motif; other site
882884012501	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884012502	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
882884012503	ornithine decarboxylase; Provisional; Region: PRK13578
882884012504	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
882884012505	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
882884012506	homodimer interface [polypeptide binding]; other site
882884012507	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884012508	catalytic residue [active]
882884012509	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
882884012510	nucleoside transporter; Region: 2A0110; TIGR00889
882884012511	murein transglycosylase C; Provisional; Region: mltC; PRK11671
882884012512	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
882884012513	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
882884012514	N-acetyl-D-glucosamine binding site [chemical binding]; other site
882884012515	catalytic residue [active]
882884012516	oxidative damage protection protein; Provisional; Region: PRK05408
882884012517	adenine DNA glycosylase; Provisional; Region: PRK10880
882884012518	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
882884012519	minor groove reading motif; other site
882884012520	helix-hairpin-helix signature motif; other site
882884012521	substrate binding pocket [chemical binding]; other site
882884012522	active site
882884012523	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
882884012524	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
882884012525	DNA binding and oxoG recognition site [nucleotide binding]
882884012526	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
882884012527	hypothetical protein; Provisional; Region: PRK11702
882884012528	hypothetical protein; Provisional; Region: PRK10626
882884012529	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
882884012530	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
882884012531	homodimer interface [polypeptide binding]; other site
882884012532	active site
882884012533	HemN family oxidoreductase; Provisional; Region: PRK05660
882884012534	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
882884012535	FeS/SAM binding site; other site
882884012536	HemN C-terminal domain; Region: HemN_C; pfam06969
882884012537	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
882884012538	active site
882884012539	dimerization interface [polypeptide binding]; other site
882884012540	hypothetical protein; Validated; Region: PRK05090
882884012541	YGGT family; Region: YGGT; pfam02325
882884012542	YGGT family; Region: YGGT; pfam02325
882884012543	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
882884012544	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
882884012545	catalytic residue [active]
882884012546	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
882884012547	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
882884012548	Walker A motif; other site
882884012549	ATP binding site [chemical binding]; other site
882884012550	Walker B motif; other site
882884012551	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
882884012552	Transcriptional regulator [Transcription]; Region: IclR; COG1414
882884012553	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
882884012554	hypothetical protein; Validated; Region: PRK00228
882884012555	glutathione synthetase; Provisional; Region: PRK05246
882884012556	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
882884012557	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
882884012558	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
882884012559	RNA methyltransferase, RsmE family; Region: TIGR00046
882884012560	DNA-specific endonuclease I; Provisional; Region: PRK15137
882884012561	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
882884012562	hypothetical protein; Provisional; Region: PRK04860
882884012563	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
882884012564	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
882884012565	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884012566	putative substrate translocation pore; other site
882884012567	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884012568	S-adenosylmethionine synthetase; Validated; Region: PRK05250
882884012569	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
882884012570	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
882884012571	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
882884012572	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
882884012573	Virulence promoting factor; Region: YqgB; pfam11036
882884012574	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
882884012575	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
882884012576	dimer interface [polypeptide binding]; other site
882884012577	active site
882884012578	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
882884012579	catalytic residues [active]
882884012580	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
882884012581	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
882884012582	agmatinase; Region: agmatinase; TIGR01230
882884012583	oligomer interface [polypeptide binding]; other site
882884012584	putative active site [active]
882884012585	Mn binding site [ion binding]; other site
882884012586	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
882884012587	transketolase; Reviewed; Region: PRK12753
882884012588	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
882884012589	TPP-binding site [chemical binding]; other site
882884012590	dimer interface [polypeptide binding]; other site
882884012591	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
882884012592	PYR/PP interface [polypeptide binding]; other site
882884012593	dimer interface [polypeptide binding]; other site
882884012594	TPP binding site [chemical binding]; other site
882884012595	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
882884012596	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
882884012597	active site
882884012598	phosphorylation site [posttranslational modification]
882884012599	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
882884012600	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
882884012601	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
882884012602	active site
882884012603	P-loop; other site
882884012604	phosphorylation site [posttranslational modification]
882884012605	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
882884012606	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
882884012607	putative NAD(P) binding site [chemical binding]; other site
882884012608	catalytic Zn binding site [ion binding]; other site
882884012609	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
882884012610	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
882884012611	putative active site [active]
882884012612	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
882884012613	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
882884012614	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
882884012615	HprK-related kinase A; Region: HprK_rel_A; TIGR04352
882884012616	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
882884012617	active site
882884012618	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
882884012619	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
882884012620	Walker A/P-loop; other site
882884012621	ATP binding site [chemical binding]; other site
882884012622	Q-loop/lid; other site
882884012623	ABC transporter signature motif; other site
882884012624	Walker B; other site
882884012625	D-loop; other site
882884012626	H-loop/switch region; other site
882884012627	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
882884012628	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
882884012629	Walker A/P-loop; other site
882884012630	ATP binding site [chemical binding]; other site
882884012631	Q-loop/lid; other site
882884012632	ABC transporter signature motif; other site
882884012633	Walker B; other site
882884012634	D-loop; other site
882884012635	H-loop/switch region; other site
882884012636	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
882884012637	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
882884012638	trimer interface [polypeptide binding]; other site
882884012639	putative Zn binding site [ion binding]; other site
882884012640	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
882884012641	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
882884012642	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
882884012643	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
882884012644	Phosphoglycerate kinase; Region: PGK; pfam00162
882884012645	substrate binding site [chemical binding]; other site
882884012646	hinge regions; other site
882884012647	ADP binding site [chemical binding]; other site
882884012648	catalytic site [active]
882884012649	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
882884012650	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
882884012651	active site
882884012652	intersubunit interface [polypeptide binding]; other site
882884012653	zinc binding site [ion binding]; other site
882884012654	Na+ binding site [ion binding]; other site
882884012655	mechanosensitive channel MscS; Provisional; Region: PRK10334
882884012656	Mechanosensitive ion channel; Region: MS_channel; pfam00924
882884012657	arginine exporter protein; Provisional; Region: PRK09304
882884012658	Uncharacterized conserved protein [Function unknown]; Region: COG2968
882884012659	oxidative stress defense protein; Provisional; Region: PRK11087
882884012660	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884012661	Transcriptional regulator [Transcription]; Region: LysR; COG0583
882884012662	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
882884012663	dimerization interface [polypeptide binding]; other site
882884012664	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
882884012665	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
882884012666	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
882884012667	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
882884012668	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
882884012669	substrate binding site [chemical binding]; other site
882884012670	oxyanion hole (OAH) forming residues; other site
882884012671	trimer interface [polypeptide binding]; other site
882884012672	membrane ATPase/protein kinase; Provisional; Region: PRK09435
882884012673	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
882884012674	Walker A; other site
882884012675	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
882884012676	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
882884012677	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
882884012678	active site
882884012679	substrate binding site [chemical binding]; other site
882884012680	coenzyme B12 binding site [chemical binding]; other site
882884012681	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
882884012682	B12 binding site [chemical binding]; other site
882884012683	cobalt ligand [ion binding]; other site
882884012684	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
882884012685	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884012686	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
882884012687	putative dimerization interface [polypeptide binding]; other site
882884012688	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
882884012689	tetramer (dimer of dimers) interface [polypeptide binding]; other site
882884012690	active site
882884012691	dimer interface [polypeptide binding]; other site
882884012692	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
882884012693	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
882884012694	ligand binding site [chemical binding]; other site
882884012695	NAD binding site [chemical binding]; other site
882884012696	tetramer interface [polypeptide binding]; other site
882884012697	catalytic site [active]
882884012698	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
882884012699	L-serine binding site [chemical binding]; other site
882884012700	ACT domain interface; other site
882884012701	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
882884012702	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
882884012703	Z-ring-associated protein; Provisional; Region: PRK10972
882884012704	hypothetical protein; Reviewed; Region: PRK01736
882884012705	proline aminopeptidase P II; Provisional; Region: PRK10879
882884012706	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
882884012707	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
882884012708	active site
882884012709	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
882884012710	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
882884012711	oxidoreductase; Provisional; Region: PRK08013
882884012712	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
882884012713	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
882884012714	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
882884012715	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
882884012716	lipoyl attachment site [posttranslational modification]; other site
882884012717	glycine dehydrogenase; Provisional; Region: PRK05367
882884012718	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
882884012719	tetramer interface [polypeptide binding]; other site
882884012720	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884012721	catalytic residue [active]
882884012722	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
882884012723	tetramer interface [polypeptide binding]; other site
882884012724	pyridoxal 5'-phosphate binding site [chemical binding]; other site
882884012725	catalytic residue [active]
882884012726	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
882884012727	beta-galactosidase; Region: BGL; TIGR03356
882884012728	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
882884012729	hemolysin; Provisional; Region: PRK15087
882884012730	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
882884012731	putative global regulator; Reviewed; Region: PRK09559
882884012732	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
882884012733	hypothetical protein; Provisional; Region: PRK10878
882884012734	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
882884012735	flavodoxin FldB; Provisional; Region: PRK12359
882884012736	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
882884012737	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
882884012738	active site
882884012739	Int/Topo IB signature motif; other site
882884012740	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
882884012741	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
882884012742	dimerization domain [polypeptide binding]; other site
882884012743	dimer interface [polypeptide binding]; other site
882884012744	catalytic residues [active]
882884012745	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
882884012746	DHH family; Region: DHH; pfam01368
882884012747	DHHA1 domain; Region: DHHA1; pfam02272
882884012748	This domain is found in peptide chain release factors; Region: PCRF; smart00937
882884012749	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
882884012750	RF-1 domain; Region: RF-1; pfam00472
882884012751	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
882884012752	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
882884012753	dimer interface [polypeptide binding]; other site
882884012754	putative anticodon binding site; other site
882884012755	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
882884012756	motif 1; other site
882884012757	active site
882884012758	motif 2; other site
882884012759	motif 3; other site
882884012760	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
882884012761	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
882884012762	active site
882884012763	metal binding site [ion binding]; metal-binding site
882884012764	nudix motif; other site
882884012765	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
882884012766	Peptidase family M23; Region: Peptidase_M23; pfam01551
882884012767	PAAR motif; Region: PAAR_motif; pfam05488
882884012768	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
882884012769	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
882884012770	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
882884012771	active site
882884012772	DNA binding site [nucleotide binding]
882884012773	Int/Topo IB signature motif; other site
882884012774	Transposase; Region: DEDD_Tnp_IS110; pfam01548
882884012775	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
882884012776	Transposase; Region: HTH_Tnp_1; cl17663
882884012777	TQO small subunit DoxD; Region: DoxD; pfam04173
882884012778	TQO small subunit DoxA; Region: DoxA; pfam07680
882884012779	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
882884012780	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
882884012781	E-class dimer interface [polypeptide binding]; other site
882884012782	P-class dimer interface [polypeptide binding]; other site
882884012783	active site
882884012784	Cu2+ binding site [ion binding]; other site
882884012785	Zn2+ binding site [ion binding]; other site
882884012786	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
882884012787	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
882884012788	Autotransporter beta-domain; Region: Autotransporter; smart00869
882884012789	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
882884012790	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
882884012791	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
882884012792	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
882884012793	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
882884012794	putative metal binding site [ion binding]; other site
882884012795	putative homodimer interface [polypeptide binding]; other site
882884012796	putative homotetramer interface [polypeptide binding]; other site
882884012797	putative homodimer-homodimer interface [polypeptide binding]; other site
882884012798	putative allosteric switch controlling residues; other site
882884012799	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
882884012800	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
882884012801	putative acyltransferase; Provisional; Region: PRK05790
882884012802	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
882884012803	dimer interface [polypeptide binding]; other site
882884012804	active site
882884012805	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
882884012806	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
882884012807	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
882884012808	NADP binding site [chemical binding]; other site
882884012809	homodimer interface [polypeptide binding]; other site
882884012810	active site
882884012811	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
882884012812	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884012813	putative substrate translocation pore; other site
882884012814	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884012815	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
882884012816	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884012817	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
882884012818	dimerization interface [polypeptide binding]; other site
882884012819	diaminopimelate decarboxylase; Provisional; Region: PRK11165
882884012820	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
882884012821	active site
882884012822	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
882884012823	substrate binding site [chemical binding]; other site
882884012824	catalytic residues [active]
882884012825	dimer interface [polypeptide binding]; other site
882884012826	Transcriptional regulators [Transcription]; Region: PurR; COG1609
882884012827	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884012828	DNA binding site [nucleotide binding]
882884012829	domain linker motif; other site
882884012830	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
882884012831	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
882884012832	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
882884012833	DNA binding site [nucleotide binding]
882884012834	domain linker motif; other site
882884012835	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
882884012836	dimerization interface (closed form) [polypeptide binding]; other site
882884012837	ligand binding site [chemical binding]; other site
882884012838	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
882884012839	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
882884012840	putative acyl-acceptor binding pocket; other site
882884012841	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
882884012842	acyl-activating enzyme (AAE) consensus motif; other site
882884012843	putative AMP binding site [chemical binding]; other site
882884012844	lysophospholipid transporter LplT; Provisional; Region: PRK11195
882884012845	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884012846	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
882884012847	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
882884012848	active site
882884012849	catalytic tetrad [active]
882884012850	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
882884012851	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
882884012852	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
882884012853	putative DNA-binding cleft [nucleotide binding]; other site
882884012854	putative DNA clevage site; other site
882884012855	molecular lever; other site
882884012856	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
882884012857	putative active site [active]
882884012858	Ap4A binding site [chemical binding]; other site
882884012859	nudix motif; other site
882884012860	putative metal binding site [ion binding]; other site
882884012861	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
882884012862	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
882884012863	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
882884012864	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
882884012865	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
882884012866	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
882884012867	thymidylate synthase; Reviewed; Region: thyA; PRK01827
882884012868	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
882884012869	dimerization interface [polypeptide binding]; other site
882884012870	active site
882884012871	hypothetical protein; Provisional; Region: PRK10506
882884012872	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
882884012873	hypothetical protein; Provisional; Region: PRK10557
882884012874	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
882884012875	hypothetical protein; Provisional; Region: PRK11521
882884012876	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
882884012877	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
882884012878	protease3; Provisional; Region: PRK15101
882884012879	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
882884012880	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
882884012881	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
882884012882	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
882884012883	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
882884012884	AAA domain; Region: AAA_30; pfam13604
882884012885	Family description; Region: UvrD_C_2; pfam13538
882884012886	N-acetylglutamate synthase; Validated; Region: PRK05279
882884012887	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
882884012888	putative feedback inhibition sensing region; other site
882884012889	putative nucleotide binding site [chemical binding]; other site
882884012890	putative substrate binding site [chemical binding]; other site
882884012891	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
882884012892	Coenzyme A binding pocket [chemical binding]; other site
882884012893	AMIN domain; Region: AMIN; pfam11741
882884012894	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
882884012895	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
882884012896	active site
882884012897	metal binding site [ion binding]; metal-binding site
882884012898	murein transglycosylase A; Provisional; Region: mltA; PRK11162
882884012899	murein hydrolase B; Provisional; Region: PRK10760; cl17906
882884012900	MltA specific insert domain; Region: MltA; smart00925
882884012901	3D domain; Region: 3D; pfam06725
882884012902	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
882884012903	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
882884012904	putative ATP binding site [chemical binding]; other site
882884012905	putative substrate interface [chemical binding]; other site
882884012906	Predicted permeases [General function prediction only]; Region: RarD; COG2962
882884012907	CsdA-binding activator; Provisional; Region: PRK15019
882884012908	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
882884012909	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
882884012910	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
882884012911	catalytic residue [active]
882884012912	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
882884012913	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
882884012914	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
882884012915	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
882884012916	dimerization interface [polypeptide binding]; other site
882884012917	substrate binding pocket [chemical binding]; other site
882884012918	hypothetical protein; Provisional; Region: PRK10873
882884012919	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
882884012920	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
882884012921	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
882884012922	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
882884012923	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
882884012924	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
882884012925	L-fuculokinase; Provisional; Region: PRK10331
882884012926	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
882884012927	nucleotide binding site [chemical binding]; other site
882884012928	L-fucose isomerase; Provisional; Region: fucI; PRK10991
882884012929	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
882884012930	hexamer (dimer of trimers) interface [polypeptide binding]; other site
882884012931	trimer interface [polypeptide binding]; other site
882884012932	substrate binding site [chemical binding]; other site
882884012933	Mn binding site [ion binding]; other site
882884012934	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
882884012935	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
882884012936	putative substrate translocation pore; other site
882884012937	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
882884012938	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
882884012939	intersubunit interface [polypeptide binding]; other site
882884012940	active site
882884012941	Zn2+ binding site [ion binding]; other site
882884012942	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
882884012943	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
882884012944	dimer interface [polypeptide binding]; other site
882884012945	active site
882884012946	metal binding site [ion binding]; metal-binding site
882884012947	flap endonuclease-like protein; Provisional; Region: PRK09482
882884012948	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
882884012949	active site
882884012950	metal binding site 1 [ion binding]; metal-binding site
882884012951	putative 5' ssDNA interaction site; other site
882884012952	metal binding site 3; metal-binding site
882884012953	metal binding site 2 [ion binding]; metal-binding site
882884012954	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
882884012955	putative DNA binding site [nucleotide binding]; other site
882884012956	putative metal binding site [ion binding]; other site
882884012957	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
882884012958	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
882884012959	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
882884012960	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
882884012961	serine transporter; Region: stp; TIGR00814
882884012962	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
882884012963	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
882884012964	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
882884012965	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
882884012966	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
882884012967	SecY interacting protein Syd; Provisional; Region: PRK04968
882884012968	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
882884012969	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
882884012970	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
882884012971	probable active site [active]
882884012972	flavodoxin; Provisional; Region: PRK08105