-- dump date   	20140620_051719
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1081093000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1081093000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1081093000003	putative catalytic residues [active]
1081093000004	putative nucleotide binding site [chemical binding]; other site
1081093000005	putative aspartate binding site [chemical binding]; other site
1081093000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1081093000007	dimer interface [polypeptide binding]; other site
1081093000008	putative threonine allosteric regulatory site; other site
1081093000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1081093000010	putative threonine allosteric regulatory site; other site
1081093000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1081093000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1081093000013	homoserine kinase; Provisional; Region: PRK01212
1081093000014	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1081093000015	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1081093000016	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1081093000017	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093000018	catalytic residue [active]
1081093000019	hypothetical protein; Validated; Region: PRK02101
1081093000020	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1081093000021	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1081093000022	transaldolase-like protein; Provisional; Region: PTZ00411
1081093000023	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1081093000024	active site
1081093000025	dimer interface [polypeptide binding]; other site
1081093000026	catalytic residue [active]
1081093000027	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1081093000028	MPT binding site; other site
1081093000029	trimer interface [polypeptide binding]; other site
1081093000030	hypothetical protein; Provisional; Region: PRK10659
1081093000031	hypothetical protein; Provisional; Region: PRK10236
1081093000032	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1081093000033	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1081093000034	Protein of unknown function (DUF2541); Region: DUF2541; cl08090
1081093000035	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1081093000036	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1081093000037	nucleotide binding site [chemical binding]; other site
1081093000038	chaperone protein DnaJ; Provisional; Region: PRK10767
1081093000039	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1081093000040	HSP70 interaction site [polypeptide binding]; other site
1081093000041	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1081093000042	substrate binding site [polypeptide binding]; other site
1081093000043	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1081093000044	Zn binding sites [ion binding]; other site
1081093000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1081093000046	dimer interface [polypeptide binding]; other site
1081093000047	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093000048	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093000049	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1081093000050	substrate binding pocket [chemical binding]; other site
1081093000051	dimerization interface [polypeptide binding]; other site
1081093000052	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1081093000053	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1081093000054	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1081093000055	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1081093000056	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
1081093000057	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
1081093000058	active site
1081093000059	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1081093000060	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
1081093000061	aromatic chitin/cellulose binding site residues [chemical binding]; other site
1081093000062	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1081093000063	Helix-turn-helix domain; Region: HTH_36; pfam13730
1081093000064	fimbrial protein BcfA; Provisional; Region: PRK15187
1081093000065	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
1081093000066	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093000067	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093000068	outer membrane usher protein; Provisional; Region: PRK15193
1081093000069	PapC N-terminal domain; Region: PapC_N; pfam13954
1081093000070	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1081093000071	PapC C-terminal domain; Region: PapC_C; pfam13953
1081093000072	fimbrial protein BcfD; Provisional; Region: PRK15189
1081093000073	Fimbrial protein; Region: Fimbrial; cl01416
1081093000074	fimbrial protein BcfF; Provisional; Region: PRK15191
1081093000075	fimbrial chaperone BcfG; Provisional; Region: PRK15192
1081093000076	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093000077	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093000078	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1081093000079	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1081093000080	catalytic residues [active]
1081093000081	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1081093000082	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093000083	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093000084	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093000085	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1081093000086	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1081093000087	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1081093000088	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1081093000089	active site
1081093000090	metal binding site [ion binding]; metal-binding site
1081093000091	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1081093000092	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
1081093000093	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1081093000094	Sulfatase; Region: Sulfatase; pfam00884
1081093000095	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1081093000096	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093000097	FeS/SAM binding site; other site
1081093000098	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1081093000099	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1081093000100	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1081093000101	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1081093000102	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093000103	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1081093000104	putative dimerization interface [polypeptide binding]; other site
1081093000105	putative alpha-glucosidase; Provisional; Region: PRK10658
1081093000106	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1081093000107	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
1081093000108	putative active site [active]
1081093000109	putative catalytic site [active]
1081093000110	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1081093000111	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
1081093000112	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1081093000113	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1081093000114	active site
1081093000115	Riboflavin kinase; Region: Flavokinase; smart00904
1081093000116	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1081093000117	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1081093000118	active site
1081093000119	HIGH motif; other site
1081093000120	nucleotide binding site [chemical binding]; other site
1081093000121	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1081093000122	active site
1081093000123	KMSKS motif; other site
1081093000124	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1081093000125	tRNA binding surface [nucleotide binding]; other site
1081093000126	anticodon binding site; other site
1081093000127	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1081093000128	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1081093000129	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1081093000130	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1081093000131	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1081093000132	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1081093000133	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1081093000134	active site
1081093000135	tetramer interface [polypeptide binding]; other site
1081093000136	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1081093000137	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093000138	active site
1081093000139	phosphorylation site [posttranslational modification]
1081093000140	intermolecular recognition site; other site
1081093000141	dimerization interface [polypeptide binding]; other site
1081093000142	Transcriptional regulator; Region: CitT; pfam12431
1081093000143	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1081093000144	PAS domain; Region: PAS; smart00091
1081093000145	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093000146	ATP binding site [chemical binding]; other site
1081093000147	Mg2+ binding site [ion binding]; other site
1081093000148	G-X-G motif; other site
1081093000149	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1081093000150	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1081093000151	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1081093000152	active site
1081093000153	catalytic residues [active]
1081093000154	metal binding site [ion binding]; metal-binding site
1081093000155	homodimer binding site [polypeptide binding]; other site
1081093000156	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1081093000157	carboxyltransferase (CT) interaction site; other site
1081093000158	biotinylation site [posttranslational modification]; other site
1081093000159	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1081093000160	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
1081093000161	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1081093000162	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1081093000163	putative active site [active]
1081093000164	(T/H)XGH motif; other site
1081093000165	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1081093000166	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1081093000167	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1081093000168	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1081093000169	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
1081093000170	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1081093000171	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1081093000172	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1081093000173	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1081093000174	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1081093000175	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1081093000176	catalytic site [active]
1081093000177	subunit interface [polypeptide binding]; other site
1081093000178	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1081093000179	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1081093000180	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1081093000181	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1081093000182	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1081093000183	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1081093000184	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1081093000185	IMP binding site; other site
1081093000186	dimer interface [polypeptide binding]; other site
1081093000187	interdomain contacts; other site
1081093000188	partial ornithine binding site; other site
1081093000189	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
1081093000190	carnitine operon protein CaiE; Provisional; Region: PRK13627
1081093000191	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1081093000192	putative trimer interface [polypeptide binding]; other site
1081093000193	putative metal binding site [ion binding]; other site
1081093000194	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
1081093000195	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1081093000196	substrate binding site [chemical binding]; other site
1081093000197	oxyanion hole (OAH) forming residues; other site
1081093000198	trimer interface [polypeptide binding]; other site
1081093000199	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
1081093000200	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
1081093000201	acyl-activating enzyme (AAE) consensus motif; other site
1081093000202	putative AMP binding site [chemical binding]; other site
1081093000203	putative active site [active]
1081093000204	putative CoA binding site [chemical binding]; other site
1081093000205	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
1081093000206	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1081093000207	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
1081093000208	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1081093000209	active site
1081093000210	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
1081093000211	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1081093000212	Ligand binding site [chemical binding]; other site
1081093000213	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1081093000214	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
1081093000215	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
1081093000216	Ligand binding site [chemical binding]; other site
1081093000217	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1081093000218	putative oxidoreductase FixC; Provisional; Region: PRK10157
1081093000219	ferredoxin-like protein FixX; Provisional; Region: PRK15449
1081093000220	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093000221	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1081093000222	putative substrate translocation pore; other site
1081093000223	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1081093000224	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093000225	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1081093000226	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1081093000227	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1081093000228	TrkA-N domain; Region: TrkA_N; pfam02254
1081093000229	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1081093000230	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1081093000231	folate binding site [chemical binding]; other site
1081093000232	NADP+ binding site [chemical binding]; other site
1081093000233	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1081093000234	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1081093000235	active site
1081093000236	metal binding site [ion binding]; metal-binding site
1081093000237	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1081093000238	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1081093000239	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1081093000240	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1081093000241	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1081093000242	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1081093000243	SurA N-terminal domain; Region: SurA_N; pfam09312
1081093000244	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1081093000245	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1081093000246	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1081093000247	OstA-like protein; Region: OstA; pfam03968
1081093000248	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1081093000249	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1081093000250	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1081093000251	putative metal binding site [ion binding]; other site
1081093000252	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1081093000253	HSP70 interaction site [polypeptide binding]; other site
1081093000254	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1081093000255	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1081093000256	active site
1081093000257	ATP-dependent helicase HepA; Validated; Region: PRK04914
1081093000258	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1081093000259	ATP binding site [chemical binding]; other site
1081093000260	putative Mg++ binding site [ion binding]; other site
1081093000261	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093000262	nucleotide binding region [chemical binding]; other site
1081093000263	ATP-binding site [chemical binding]; other site
1081093000264	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1081093000265	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1081093000266	putative active site [active]
1081093000267	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1081093000268	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1081093000269	intersubunit interface [polypeptide binding]; other site
1081093000270	active site
1081093000271	Zn2+ binding site [ion binding]; other site
1081093000272	L-arabinose isomerase; Provisional; Region: PRK02929
1081093000273	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1081093000274	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1081093000275	trimer interface [polypeptide binding]; other site
1081093000276	putative substrate binding site [chemical binding]; other site
1081093000277	putative metal binding site [ion binding]; other site
1081093000278	ribulokinase; Provisional; Region: PRK04123
1081093000279	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1081093000280	N- and C-terminal domain interface [polypeptide binding]; other site
1081093000281	active site
1081093000282	MgATP binding site [chemical binding]; other site
1081093000283	catalytic site [active]
1081093000284	metal binding site [ion binding]; metal-binding site
1081093000285	carbohydrate binding site [chemical binding]; other site
1081093000286	homodimer interface [polypeptide binding]; other site
1081093000287	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1081093000288	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1081093000289	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093000290	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093000291	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1081093000292	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1081093000293	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1081093000294	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1081093000295	Walker A/P-loop; other site
1081093000296	ATP binding site [chemical binding]; other site
1081093000297	Q-loop/lid; other site
1081093000298	ABC transporter signature motif; other site
1081093000299	Walker B; other site
1081093000300	D-loop; other site
1081093000301	H-loop/switch region; other site
1081093000302	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1081093000303	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093000304	dimer interface [polypeptide binding]; other site
1081093000305	conserved gate region; other site
1081093000306	putative PBP binding loops; other site
1081093000307	ABC-ATPase subunit interface; other site
1081093000308	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093000309	dimer interface [polypeptide binding]; other site
1081093000310	conserved gate region; other site
1081093000311	putative PBP binding loops; other site
1081093000312	ABC-ATPase subunit interface; other site
1081093000313	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1081093000314	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1081093000315	transcriptional regulator SgrR; Provisional; Region: PRK13626
1081093000316	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1081093000317	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1081093000318	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1081093000319	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1081093000320	substrate binding site [chemical binding]; other site
1081093000321	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1081093000322	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1081093000323	substrate binding site [chemical binding]; other site
1081093000324	ligand binding site [chemical binding]; other site
1081093000325	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1081093000326	tartrate dehydrogenase; Region: TTC; TIGR02089
1081093000327	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1081093000328	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093000329	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1081093000330	putative substrate binding pocket [chemical binding]; other site
1081093000331	putative dimerization interface [polypeptide binding]; other site
1081093000332	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1081093000333	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1081093000334	putative valine binding site [chemical binding]; other site
1081093000335	dimer interface [polypeptide binding]; other site
1081093000336	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1081093000337	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1081093000338	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093000339	DNA binding site [nucleotide binding]
1081093000340	domain linker motif; other site
1081093000341	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1081093000342	dimerization interface [polypeptide binding]; other site
1081093000343	ligand binding site [chemical binding]; other site
1081093000344	mraZ protein; Region: TIGR00242
1081093000345	MraZ protein; Region: MraZ; pfam02381
1081093000346	MraZ protein; Region: MraZ; pfam02381
1081093000347	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1081093000348	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1081093000349	cell division protein FtsL; Provisional; Region: PRK10772
1081093000350	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1081093000351	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1081093000352	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1081093000353	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1081093000354	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1081093000355	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1081093000356	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1081093000357	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1081093000358	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1081093000359	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1081093000360	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1081093000361	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1081093000362	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1081093000363	Mg++ binding site [ion binding]; other site
1081093000364	putative catalytic motif [active]
1081093000365	putative substrate binding site [chemical binding]; other site
1081093000366	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1081093000367	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1081093000368	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1081093000369	cell division protein FtsW; Provisional; Region: PRK10774
1081093000370	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1081093000371	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1081093000372	active site
1081093000373	homodimer interface [polypeptide binding]; other site
1081093000374	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1081093000375	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1081093000376	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1081093000377	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1081093000378	cell division protein FtsQ; Provisional; Region: PRK10775
1081093000379	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1081093000380	Cell division protein FtsQ; Region: FtsQ; pfam03799
1081093000381	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1081093000382	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1081093000383	Cell division protein FtsA; Region: FtsA; pfam14450
1081093000384	cell division protein FtsZ; Validated; Region: PRK09330
1081093000385	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1081093000386	nucleotide binding site [chemical binding]; other site
1081093000387	SulA interaction site; other site
1081093000388	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
1081093000389	UDP-3-0-acyl N-acetylglucosamine deacetylase; Region: lpxC; TIGR00325
1081093000390	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1081093000391	SecA regulator SecM; Provisional; Region: PRK02943
1081093000392	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1081093000393	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1081093000394	SEC-C motif; Region: SEC-C; pfam02810
1081093000395	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1081093000396	active site
1081093000397	8-oxo-dGMP binding site [chemical binding]; other site
1081093000398	nudix motif; other site
1081093000399	metal binding site [ion binding]; metal-binding site
1081093000400	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093000401	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093000402	active site
1081093000403	catalytic tetrad [active]
1081093000404	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1081093000405	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
1081093000406	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1081093000407	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1081093000408	CoA-binding site [chemical binding]; other site
1081093000409	ATP-binding [chemical binding]; other site
1081093000410	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1081093000411	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1081093000412	active site
1081093000413	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1081093000414	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1081093000415	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1081093000416	hypothetical protein; Provisional; Region: PRK10436
1081093000417	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1081093000418	Walker A motif; other site
1081093000419	ATP binding site [chemical binding]; other site
1081093000420	Walker B motif; other site
1081093000421	putative major pilin subunit; Provisional; Region: PRK10574
1081093000422	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1081093000423	Pilin (bacterial filament); Region: Pilin; pfam00114
1081093000424	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1081093000425	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1081093000426	dimerization interface [polypeptide binding]; other site
1081093000427	active site
1081093000428	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1081093000429	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1081093000430	amidase catalytic site [active]
1081093000431	Zn binding residues [ion binding]; other site
1081093000432	substrate binding site [chemical binding]; other site
1081093000433	regulatory protein AmpE; Provisional; Region: PRK10987
1081093000434	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1081093000435	active site
1081093000436	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1081093000437	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093000438	putative substrate translocation pore; other site
1081093000439	aromatic amino acid transporter; Provisional; Region: PRK10238
1081093000440	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1081093000441	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093000442	DNA-binding site [nucleotide binding]; DNA binding site
1081093000443	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1081093000444	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1081093000445	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1081093000446	dimer interface [polypeptide binding]; other site
1081093000447	TPP-binding site [chemical binding]; other site
1081093000448	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1081093000449	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1081093000450	E3 interaction surface; other site
1081093000451	lipoyl attachment site [posttranslational modification]; other site
1081093000452	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1081093000453	E3 interaction surface; other site
1081093000454	lipoyl attachment site [posttranslational modification]; other site
1081093000455	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1081093000456	E3 interaction surface; other site
1081093000457	lipoyl attachment site [posttranslational modification]; other site
1081093000458	e3 binding domain; Region: E3_binding; pfam02817
1081093000459	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1081093000460	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1081093000461	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1081093000462	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093000463	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1081093000464	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1081093000465	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1081093000466	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1081093000467	substrate binding site [chemical binding]; other site
1081093000468	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1081093000469	substrate binding site [chemical binding]; other site
1081093000470	ligand binding site [chemical binding]; other site
1081093000471	putative inner membrane protein; Provisional; Region: PRK09823
1081093000472	Low molecular weight phosphatase family; Region: LMWPc; cl00105
1081093000473	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1081093000474	active site
1081093000475	hypothetical protein; Provisional; Region: PRK05248
1081093000476	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
1081093000477	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1081093000478	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1081093000479	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
1081093000480	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093000481	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1081093000482	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093000483	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1081093000484	spermidine synthase; Provisional; Region: PRK00811
1081093000485	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093000486	S-adenosylmethionine binding site [chemical binding]; other site
1081093000487	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1081093000488	multicopper oxidase; Provisional; Region: PRK10965
1081093000489	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1081093000490	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1081093000491	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1081093000492	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1081093000493	Trp docking motif [polypeptide binding]; other site
1081093000494	putative active site [active]
1081093000495	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1081093000496	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1081093000497	active site
1081093000498	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1081093000499	active site clefts [active]
1081093000500	zinc binding site [ion binding]; other site
1081093000501	dimer interface [polypeptide binding]; other site
1081093000502	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1081093000503	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1081093000504	Walker A/P-loop; other site
1081093000505	ATP binding site [chemical binding]; other site
1081093000506	Q-loop/lid; other site
1081093000507	ABC transporter signature motif; other site
1081093000508	Walker B; other site
1081093000509	D-loop; other site
1081093000510	H-loop/switch region; other site
1081093000511	inner membrane transport permease; Provisional; Region: PRK15066
1081093000512	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1081093000513	putative fimbrial protein StiH; Provisional; Region: PRK15297
1081093000514	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093000515	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093000516	fimbrial protein StiA; Provisional; Region: PRK15300
1081093000517	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1081093000518	active pocket/dimerization site; other site
1081093000519	active site
1081093000520	phosphorylation site [posttranslational modification]
1081093000521	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1081093000522	putative active site [active]
1081093000523	putative metal binding site [ion binding]; other site
1081093000524	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1081093000525	tetramerization interface [polypeptide binding]; other site
1081093000526	active site
1081093000527	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1081093000528	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1081093000529	active site
1081093000530	ATP-binding site [chemical binding]; other site
1081093000531	pantoate-binding site; other site
1081093000532	HXXH motif; other site
1081093000533	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1081093000534	oligomerization interface [polypeptide binding]; other site
1081093000535	active site
1081093000536	metal binding site [ion binding]; metal-binding site
1081093000537	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1081093000538	catalytic center binding site [active]
1081093000539	ATP binding site [chemical binding]; other site
1081093000540	poly(A) polymerase; Region: pcnB; TIGR01942
1081093000541	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1081093000542	active site
1081093000543	NTP binding site [chemical binding]; other site
1081093000544	metal binding triad [ion binding]; metal-binding site
1081093000545	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1081093000546	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1081093000547	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1081093000548	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1081093000549	active site
1081093000550	nucleotide binding site [chemical binding]; other site
1081093000551	HIGH motif; other site
1081093000552	KMSKS motif; other site
1081093000553	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1081093000554	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1081093000555	2'-5' RNA ligase; Provisional; Region: PRK15124
1081093000556	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1081093000557	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1081093000558	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1081093000559	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1081093000560	ATP binding site [chemical binding]; other site
1081093000561	putative Mg++ binding site [ion binding]; other site
1081093000562	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093000563	nucleotide binding region [chemical binding]; other site
1081093000564	ATP-binding site [chemical binding]; other site
1081093000565	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1081093000566	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1081093000567	Transglycosylase; Region: Transgly; pfam00912
1081093000568	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1081093000569	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1081093000570	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1081093000571	N-terminal plug; other site
1081093000572	ligand-binding site [chemical binding]; other site
1081093000573	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1081093000574	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1081093000575	Walker A/P-loop; other site
1081093000576	ATP binding site [chemical binding]; other site
1081093000577	Q-loop/lid; other site
1081093000578	ABC transporter signature motif; other site
1081093000579	Walker B; other site
1081093000580	D-loop; other site
1081093000581	H-loop/switch region; other site
1081093000582	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1081093000583	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1081093000584	siderophore binding site; other site
1081093000585	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1081093000586	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1081093000587	ABC-ATPase subunit  interface; other site
1081093000588	dimer interface [polypeptide binding]; other site
1081093000589	putative PBP binding regions; other site
1081093000590	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1081093000591	ABC-ATPase subunit  interface; other site
1081093000592	dimer interface [polypeptide binding]; other site
1081093000593	putative PBP binding regions; other site
1081093000594	putative fimbrial subunit StfA; Provisional; Region: PRK15283
1081093000595	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
1081093000596	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093000597	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093000598	putative minor fimbrial subunit StfE; Provisional; Region: PRK15286
1081093000599	putative minor fimbrial subunit StfG; Provisional; Region: PRK15288
1081093000600	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1081093000601	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1081093000602	inhibitor-cofactor binding pocket; inhibition site
1081093000603	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093000604	catalytic residue [active]
1081093000605	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1081093000606	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1081093000607	Cl- selectivity filter; other site
1081093000608	Cl- binding residues [ion binding]; other site
1081093000609	pore gating glutamate residue; other site
1081093000610	dimer interface [polypeptide binding]; other site
1081093000611	H+/Cl- coupling transport residue; other site
1081093000612	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1081093000613	hypothetical protein; Provisional; Region: PRK10578
1081093000614	UPF0126 domain; Region: UPF0126; pfam03458
1081093000615	UPF0126 domain; Region: UPF0126; pfam03458
1081093000616	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1081093000617	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1081093000618	cobalamin binding residues [chemical binding]; other site
1081093000619	putative BtuC binding residues; other site
1081093000620	dimer interface [polypeptide binding]; other site
1081093000621	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1081093000622	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1081093000623	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1081093000624	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1081093000625	Zn2+ binding site [ion binding]; other site
1081093000626	Mg2+ binding site [ion binding]; other site
1081093000627	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1081093000628	serine endoprotease; Provisional; Region: PRK10942
1081093000629	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1081093000630	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1081093000631	protein binding site [polypeptide binding]; other site
1081093000632	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1081093000633	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1081093000634	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1081093000635	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1081093000636	hypothetical protein; Provisional; Region: PRK13677
1081093000637	shikimate transporter; Provisional; Region: PRK09952
1081093000638	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093000639	putative substrate translocation pore; other site
1081093000640	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1081093000641	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1081093000642	trimer interface [polypeptide binding]; other site
1081093000643	active site
1081093000644	substrate binding site [chemical binding]; other site
1081093000645	CoA binding site [chemical binding]; other site
1081093000646	PII uridylyl-transferase; Provisional; Region: PRK05007
1081093000647	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1081093000648	metal binding triad; other site
1081093000649	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1081093000650	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1081093000651	Zn2+ binding site [ion binding]; other site
1081093000652	Mg2+ binding site [ion binding]; other site
1081093000653	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1081093000654	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1081093000655	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1081093000656	active site
1081093000657	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1081093000658	rRNA interaction site [nucleotide binding]; other site
1081093000659	S8 interaction site; other site
1081093000660	putative laminin-1 binding site; other site
1081093000661	elongation factor Ts; Provisional; Region: tsf; PRK09377
1081093000662	UBA/TS-N domain; Region: UBA; pfam00627
1081093000663	Elongation factor TS; Region: EF_TS; pfam00889
1081093000664	Elongation factor TS; Region: EF_TS; pfam00889
1081093000665	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1081093000666	putative nucleotide binding site [chemical binding]; other site
1081093000667	uridine monophosphate binding site [chemical binding]; other site
1081093000668	homohexameric interface [polypeptide binding]; other site
1081093000669	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1081093000670	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1081093000671	hinge region; other site
1081093000672	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1081093000673	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1081093000674	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1081093000675	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1081093000676	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1081093000677	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1081093000678	catalytic residue [active]
1081093000679	putative FPP diphosphate  binding site; other site
1081093000680	putative FPP binding hydrophobic cleft; other site
1081093000681	dimer interface [polypeptide binding]; other site
1081093000682	putative IPP diphosphate binding site; other site
1081093000683	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1081093000684	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1081093000685	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1081093000686	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1081093000687	active site
1081093000688	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1081093000689	protein binding site [polypeptide binding]; other site
1081093000690	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1081093000691	protein binding site [polypeptide binding]; other site
1081093000692	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1081093000693	putative substrate binding region [chemical binding]; other site
1081093000694	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1081093000695	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1081093000696	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1081093000697	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1081093000698	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1081093000699	Surface antigen; Region: Bac_surface_Ag; pfam01103
1081093000700	periplasmic chaperone; Provisional; Region: PRK10780
1081093000701	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1081093000702	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1081093000703	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1081093000704	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1081093000705	trimer interface [polypeptide binding]; other site
1081093000706	active site
1081093000707	UDP-GlcNAc binding site [chemical binding]; other site
1081093000708	lipid binding site [chemical binding]; lipid-binding site
1081093000709	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1081093000710	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1081093000711	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1081093000712	active site
1081093000713	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1081093000714	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1081093000715	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1081093000716	RNA/DNA hybrid binding site [nucleotide binding]; other site
1081093000717	active site
1081093000718	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1081093000719	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1081093000720	putative active site [active]
1081093000721	putative PHP Thumb interface [polypeptide binding]; other site
1081093000722	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1081093000723	generic binding surface II; other site
1081093000724	generic binding surface I; other site
1081093000725	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1081093000726	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1081093000727	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1081093000728	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
1081093000729	putative sugar binding site [chemical binding]; other site
1081093000730	catalytic residues [active]
1081093000731	PKD domain; Region: PKD; pfam00801
1081093000732	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1081093000733	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1081093000734	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1081093000735	homodimer interface [polypeptide binding]; other site
1081093000736	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093000737	catalytic residue [active]
1081093000738	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1081093000739	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1081093000740	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1081093000741	putative metal binding site [ion binding]; other site
1081093000742	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1081093000743	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1081093000744	Ligand Binding Site [chemical binding]; other site
1081093000745	TilS substrate binding domain; Region: TilS; pfam09179
1081093000746	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1081093000747	Modulator of Rho-dependent transcription termination (ROF); Region: ROF; cl09210
1081093000748	hypothetical protein; Provisional; Region: PRK04964
1081093000749	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1081093000750	hypothetical protein; Provisional; Region: PRK09256
1081093000751	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1081093000752	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1081093000753	NlpE N-terminal domain; Region: NlpE; pfam04170
1081093000754	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1081093000755	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1081093000756	dimer interface [polypeptide binding]; other site
1081093000757	motif 1; other site
1081093000758	active site
1081093000759	motif 2; other site
1081093000760	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1081093000761	putative deacylase active site [active]
1081093000762	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1081093000763	active site
1081093000764	motif 3; other site
1081093000765	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1081093000766	anticodon binding site; other site
1081093000767	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1081093000768	homodimer interaction site [polypeptide binding]; other site
1081093000769	cofactor binding site; other site
1081093000770	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1081093000771	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1081093000772	lipoprotein, YaeC family; Region: TIGR00363
1081093000773	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093000774	dimer interface [polypeptide binding]; other site
1081093000775	conserved gate region; other site
1081093000776	ABC-ATPase subunit interface; other site
1081093000777	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1081093000778	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1081093000779	Walker A/P-loop; other site
1081093000780	ATP binding site [chemical binding]; other site
1081093000781	Q-loop/lid; other site
1081093000782	ABC transporter signature motif; other site
1081093000783	Walker B; other site
1081093000784	D-loop; other site
1081093000785	H-loop/switch region; other site
1081093000786	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1081093000787	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1081093000788	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093000789	active site
1081093000790	motif I; other site
1081093000791	motif II; other site
1081093000792	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1081093000793	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1081093000794	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093000795	putative substrate translocation pore; other site
1081093000796	lipoprotein; Provisional; Region: PRK10759
1081093000797	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1081093000798	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1081093000799	domain interface [polypeptide binding]; other site
1081093000800	putative active site [active]
1081093000801	catalytic site [active]
1081093000802	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1081093000803	domain interface [polypeptide binding]; other site
1081093000804	putative active site [active]
1081093000805	catalytic site [active]
1081093000806	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1081093000807	CoA binding domain; Region: CoA_binding_2; pfam13380
1081093000808	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1081093000809	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1081093000810	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1081093000811	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093000812	Coenzyme A binding pocket [chemical binding]; other site
1081093000813	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1081093000814	putative methyltransferase; Provisional; Region: PRK10864
1081093000815	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1081093000816	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1081093000817	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1081093000818	ligand binding site [chemical binding]; other site
1081093000819	active site
1081093000820	UGI interface [polypeptide binding]; other site
1081093000821	catalytic site [active]
1081093000822	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1081093000823	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093000824	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093000825	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1081093000826	dimerization interface [polypeptide binding]; other site
1081093000827	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1081093000828	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1081093000829	ATP binding site [chemical binding]; other site
1081093000830	Mg++ binding site [ion binding]; other site
1081093000831	motif III; other site
1081093000832	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093000833	nucleotide binding region [chemical binding]; other site
1081093000834	ATP-binding site [chemical binding]; other site
1081093000835	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1081093000836	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093000837	S-adenosylmethionine binding site [chemical binding]; other site
1081093000838	L-aspartate oxidase; Provisional; Region: PRK09077
1081093000839	L-aspartate oxidase; Provisional; Region: PRK06175
1081093000840	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1081093000841	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1081093000842	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1081093000843	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1081093000844	DNA binding residues [nucleotide binding]
1081093000845	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1081093000846	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1081093000847	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1081093000848	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1081093000849	MucB/RseB family; Region: MucB_RseB; pfam03888
1081093000850	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1081093000851	GTP-binding protein LepA; Provisional; Region: PRK05433
1081093000852	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1081093000853	G1 box; other site
1081093000854	putative GEF interaction site [polypeptide binding]; other site
1081093000855	GTP/Mg2+ binding site [chemical binding]; other site
1081093000856	Switch I region; other site
1081093000857	G2 box; other site
1081093000858	G3 box; other site
1081093000859	Switch II region; other site
1081093000860	G4 box; other site
1081093000861	G5 box; other site
1081093000862	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1081093000863	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1081093000864	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1081093000865	signal peptidase I; Provisional; Region: PRK10861
1081093000866	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1081093000867	Catalytic site [active]
1081093000868	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1081093000869	ribonuclease III; Reviewed; Region: rnc; PRK00102
1081093000870	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1081093000871	dimerization interface [polypeptide binding]; other site
1081093000872	active site
1081093000873	metal binding site [ion binding]; metal-binding site
1081093000874	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1081093000875	dsRNA binding site [nucleotide binding]; other site
1081093000876	GTPase Era; Reviewed; Region: era; PRK00089
1081093000877	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1081093000878	G1 box; other site
1081093000879	GTP/Mg2+ binding site [chemical binding]; other site
1081093000880	Switch I region; other site
1081093000881	G2 box; other site
1081093000882	Switch II region; other site
1081093000883	G3 box; other site
1081093000884	G4 box; other site
1081093000885	G5 box; other site
1081093000886	KH domain; Region: KH_2; pfam07650
1081093000887	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1081093000888	Recombination protein O N terminal; Region: RecO_N; pfam11967
1081093000889	Recombination protein O C terminal; Region: RecO_C; pfam02565
1081093000890	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1081093000891	active site
1081093000892	hydrophilic channel; other site
1081093000893	dimerization interface [polypeptide binding]; other site
1081093000894	catalytic residues [active]
1081093000895	active site lid [active]
1081093000896	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1081093000897	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1081093000898	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093000899	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093000900	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1081093000901	dimerization interface [polypeptide binding]; other site
1081093000902	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1081093000903	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093000904	putative substrate translocation pore; other site
1081093000905	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1081093000906	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1081093000907	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1081093000908	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1081093000909	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1081093000910	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1081093000911	putative active site [active]
1081093000912	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1081093000913	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1081093000914	putative active site [active]
1081093000915	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1081093000916	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1081093000917	active site turn [active]
1081093000918	phosphorylation site [posttranslational modification]
1081093000919	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1081093000920	hypothetical protein; Provisional; Region: PRK11590
1081093000921	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1081093000922	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1081093000923	nucleoside/Zn binding site; other site
1081093000924	dimer interface [polypeptide binding]; other site
1081093000925	catalytic motif [active]
1081093000926	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1081093000927	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093000928	substrate binding pocket [chemical binding]; other site
1081093000929	membrane-bound complex binding site; other site
1081093000930	hinge residues; other site
1081093000931	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1081093000932	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1081093000933	catalytic residue [active]
1081093000934	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1081093000935	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1081093000936	dimerization interface [polypeptide binding]; other site
1081093000937	ATP binding site [chemical binding]; other site
1081093000938	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
1081093000939	dimerization interface [polypeptide binding]; other site
1081093000940	ATP binding site [chemical binding]; other site
1081093000941	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1081093000942	putative active site [active]
1081093000943	catalytic triad [active]
1081093000944	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1081093000945	HAMP domain; Region: HAMP; pfam00672
1081093000946	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093000947	dimer interface [polypeptide binding]; other site
1081093000948	phosphorylation site [posttranslational modification]
1081093000949	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093000950	ATP binding site [chemical binding]; other site
1081093000951	Mg2+ binding site [ion binding]; other site
1081093000952	G-X-G motif; other site
1081093000953	hypothetical protein; Provisional; Region: PRK10722
1081093000954	response regulator GlrR; Provisional; Region: PRK15115
1081093000955	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093000956	active site
1081093000957	phosphorylation site [posttranslational modification]
1081093000958	intermolecular recognition site; other site
1081093000959	dimerization interface [polypeptide binding]; other site
1081093000960	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093000961	Walker A motif; other site
1081093000962	ATP binding site [chemical binding]; other site
1081093000963	Walker B motif; other site
1081093000964	arginine finger; other site
1081093000965	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1081093000966	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1081093000967	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1081093000968	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093000969	putative substrate translocation pore; other site
1081093000970	POT family; Region: PTR2; pfam00854
1081093000971	lysine decarboxylase CadA; Provisional; Region: PRK15400
1081093000972	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1081093000973	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1081093000974	homodimer interface [polypeptide binding]; other site
1081093000975	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093000976	catalytic residue [active]
1081093000977	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1081093000978	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1081093000979	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1081093000980	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093000981	DNA binding site [nucleotide binding]
1081093000982	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1081093000983	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1081093000984	heme-binding site [chemical binding]; other site
1081093000985	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1081093000986	FAD binding pocket [chemical binding]; other site
1081093000987	FAD binding motif [chemical binding]; other site
1081093000988	phosphate binding motif [ion binding]; other site
1081093000989	beta-alpha-beta structure motif; other site
1081093000990	NAD binding pocket [chemical binding]; other site
1081093000991	Heme binding  pocket [chemical binding]; other site
1081093000992	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1081093000993	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1081093000994	dimer interface [polypeptide binding]; other site
1081093000995	active site
1081093000996	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1081093000997	folate binding site [chemical binding]; other site
1081093000998	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1081093000999	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093001000	putative substrate translocation pore; other site
1081093001001	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1081093001002	PRD domain; Region: PRD; pfam00874
1081093001003	PRD domain; Region: PRD; pfam00874
1081093001004	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
1081093001005	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1081093001006	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
1081093001007	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1081093001008	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1081093001009	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
1081093001010	FAD binding pocket [chemical binding]; other site
1081093001011	FAD binding motif [chemical binding]; other site
1081093001012	phosphate binding motif [ion binding]; other site
1081093001013	beta-alpha-beta structure motif; other site
1081093001014	NAD binding pocket [chemical binding]; other site
1081093001015	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1081093001016	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1081093001017	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1081093001018	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1081093001019	active site
1081093001020	dimerization interface [polypeptide binding]; other site
1081093001021	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1081093001022	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1081093001023	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1081093001024	Rrf2 family protein; Region: rrf2_super; TIGR00738
1081093001025	cysteine desulfurase; Provisional; Region: PRK14012
1081093001026	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1081093001027	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1081093001028	catalytic residue [active]
1081093001029	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1081093001030	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1081093001031	trimerization site [polypeptide binding]; other site
1081093001032	active site
1081093001033	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1081093001034	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1081093001035	DnaJ domain; Region: DnaJ; pfam00226
1081093001036	HSP70 interaction site [polypeptide binding]; other site
1081093001037	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1081093001038	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1081093001039	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1081093001040	nucleotide binding site [chemical binding]; other site
1081093001041	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1081093001042	SBD interface [polypeptide binding]; other site
1081093001043	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1081093001044	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1081093001045	catalytic loop [active]
1081093001046	iron binding site [ion binding]; other site
1081093001047	hypothetical protein; Provisional; Region: PRK10721
1081093001048	aminopeptidase B; Provisional; Region: PRK05015
1081093001049	Peptidase; Region: DUF3663; pfam12404
1081093001050	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1081093001051	interface (dimer of trimers) [polypeptide binding]; other site
1081093001052	Substrate-binding/catalytic site; other site
1081093001053	Zn-binding sites [ion binding]; other site
1081093001054	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1081093001055	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1081093001056	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1081093001057	active site residue [active]
1081093001058	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1081093001059	active site residue [active]
1081093001060	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1081093001061	MG2 domain; Region: A2M_N; pfam01835
1081093001062	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1081093001063	surface patch; other site
1081093001064	thioester region; other site
1081093001065	specificity defining residues; other site
1081093001066	penicillin-binding protein 1C; Provisional; Region: PRK11240
1081093001067	Transglycosylase; Region: Transgly; pfam00912
1081093001068	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1081093001069	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1081093001070	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1081093001071	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1081093001072	putative [Fe4-S4] binding site [ion binding]; other site
1081093001073	putative molybdopterin cofactor binding site [chemical binding]; other site
1081093001074	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1081093001075	putative molybdopterin cofactor binding site; other site
1081093001076	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1081093001077	4Fe-4S binding domain; Region: Fer4; pfam00037
1081093001078	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1081093001079	4Fe-4S binding domain; Region: Fer4; pfam00037
1081093001080	hydrogenase 4 subunit H; Validated; Region: PRK08222
1081093001081	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1081093001082	active site
1081093001083	multimer interface [polypeptide binding]; other site
1081093001084	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1081093001085	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093001086	FeS/SAM binding site; other site
1081093001087	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1081093001088	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093001089	non-specific DNA binding site [nucleotide binding]; other site
1081093001090	salt bridge; other site
1081093001091	sequence-specific DNA binding site [nucleotide binding]; other site
1081093001092	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1081093001093	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1081093001094	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1081093001095	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1081093001096	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1081093001097	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1081093001098	dimer interface [polypeptide binding]; other site
1081093001099	motif 1; other site
1081093001100	active site
1081093001101	motif 2; other site
1081093001102	motif 3; other site
1081093001103	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1081093001104	anticodon binding site; other site
1081093001105	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1081093001106	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1081093001107	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1081093001108	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
1081093001109	Trp docking motif [polypeptide binding]; other site
1081093001110	GTP-binding protein Der; Reviewed; Region: PRK00093
1081093001111	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1081093001112	G1 box; other site
1081093001113	GTP/Mg2+ binding site [chemical binding]; other site
1081093001114	Switch I region; other site
1081093001115	G2 box; other site
1081093001116	Switch II region; other site
1081093001117	G3 box; other site
1081093001118	G4 box; other site
1081093001119	G5 box; other site
1081093001120	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1081093001121	G1 box; other site
1081093001122	GTP/Mg2+ binding site [chemical binding]; other site
1081093001123	Switch I region; other site
1081093001124	G2 box; other site
1081093001125	G3 box; other site
1081093001126	Switch II region; other site
1081093001127	G4 box; other site
1081093001128	G5 box; other site
1081093001129	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1081093001130	intimin-like protein SinH; Provisional; Region: PRK15318
1081093001131	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1081093001132	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1081093001133	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1081093001134	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1081093001135	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1081093001136	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1081093001137	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1081093001138	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1081093001139	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1081093001140	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1081093001141	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1081093001142	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1081093001143	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1081093001144	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1081093001145	Autotransporter beta-domain; Region: Autotransporter; smart00869
1081093001146	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1081093001147	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1081093001148	generic binding surface II; other site
1081093001149	generic binding surface I; other site
1081093001150	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1081093001151	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1081093001152	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1081093001153	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1081093001154	active site
1081093001155	GMP synthase; Reviewed; Region: guaA; PRK00074
1081093001156	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1081093001157	AMP/PPi binding site [chemical binding]; other site
1081093001158	candidate oxyanion hole; other site
1081093001159	catalytic triad [active]
1081093001160	potential glutamine specificity residues [chemical binding]; other site
1081093001161	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1081093001162	ATP Binding subdomain [chemical binding]; other site
1081093001163	Ligand Binding sites [chemical binding]; other site
1081093001164	Dimerization subdomain; other site
1081093001165	Integrase core domain; Region: rve; pfam00665
1081093001166	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1081093001167	exopolyphosphatase; Provisional; Region: PRK10854
1081093001168	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1081093001169	nucleotide binding site [chemical binding]; other site
1081093001170	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1081093001171	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1081093001172	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1081093001173	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1081093001174	putative active site [active]
1081093001175	catalytic site [active]
1081093001176	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1081093001177	domain interface [polypeptide binding]; other site
1081093001178	active site
1081093001179	catalytic site [active]
1081093001180	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1081093001181	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1081093001182	active site
1081093001183	substrate binding site [chemical binding]; other site
1081093001184	cosubstrate binding site; other site
1081093001185	catalytic site [active]
1081093001186	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1081093001187	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1081093001188	dimerization interface [polypeptide binding]; other site
1081093001189	putative ATP binding site [chemical binding]; other site
1081093001190	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1081093001191	active site
1081093001192	uracil transporter; Provisional; Region: PRK10720
1081093001193	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1081093001194	DNA replication initiation factor; Provisional; Region: PRK08084
1081093001195	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1081093001196	ArsC family; Region: ArsC; pfam03960
1081093001197	catalytic residues [active]
1081093001198	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1081093001199	Peptidase family M48; Region: Peptidase_M48; cl12018
1081093001200	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1081093001201	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1081093001202	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1081093001203	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1081093001204	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1081093001205	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1081093001206	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1081093001207	catalytic triad [active]
1081093001208	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1081093001209	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1081093001210	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1081093001211	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1081093001212	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1081093001213	dimer interface [polypeptide binding]; other site
1081093001214	active site
1081093001215	catalytic residue [active]
1081093001216	lipoprotein; Provisional; Region: PRK11679
1081093001217	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1081093001218	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1081093001219	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1081093001220	ATP binding site [chemical binding]; other site
1081093001221	active site
1081093001222	substrate binding site [chemical binding]; other site
1081093001223	Predicted metalloprotease [General function prediction only]; Region: COG2321
1081093001224	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1081093001225	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1081093001226	Helicase; Region: Helicase_RecD; pfam05127
1081093001227	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1081093001228	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1081093001229	hypothetical protein; Provisional; Region: PRK13664
1081093001230	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1081093001231	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1081093001232	metal binding site [ion binding]; metal-binding site
1081093001233	dimer interface [polypeptide binding]; other site
1081093001234	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1081093001235	ArsC family; Region: ArsC; pfam03960
1081093001236	putative catalytic residues [active]
1081093001237	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1081093001238	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1081093001239	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093001240	dimerization interface [polypeptide binding]; other site
1081093001241	Histidine kinase; Region: HisKA_3; pfam07730
1081093001242	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093001243	ATP binding site [chemical binding]; other site
1081093001244	Mg2+ binding site [ion binding]; other site
1081093001245	G-X-G motif; other site
1081093001246	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1081093001247	4Fe-4S binding domain; Region: Fer4; pfam00037
1081093001248	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1081093001249	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093001250	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1081093001251	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1081093001252	dimer interface [polypeptide binding]; other site
1081093001253	ADP-ribose binding site [chemical binding]; other site
1081093001254	active site
1081093001255	nudix motif; other site
1081093001256	metal binding site [ion binding]; metal-binding site
1081093001257	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1081093001258	transketolase; Reviewed; Region: PRK12753
1081093001259	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1081093001260	TPP-binding site [chemical binding]; other site
1081093001261	dimer interface [polypeptide binding]; other site
1081093001262	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1081093001263	PYR/PP interface [polypeptide binding]; other site
1081093001264	dimer interface [polypeptide binding]; other site
1081093001265	TPP binding site [chemical binding]; other site
1081093001266	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1081093001267	transaldolase-like protein; Provisional; Region: PTZ00411
1081093001268	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1081093001269	active site
1081093001270	dimer interface [polypeptide binding]; other site
1081093001271	catalytic residue [active]
1081093001272	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1081093001273	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1081093001274	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1081093001275	putative NAD(P) binding site [chemical binding]; other site
1081093001276	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1081093001277	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1081093001278	putative hexamer interface [polypeptide binding]; other site
1081093001279	putative hexagonal pore; other site
1081093001280	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1081093001281	G1 box; other site
1081093001282	GTP/Mg2+ binding site [chemical binding]; other site
1081093001283	G2 box; other site
1081093001284	Switch I region; other site
1081093001285	G3 box; other site
1081093001286	Switch II region; other site
1081093001287	G4 box; other site
1081093001288	G5 box; other site
1081093001289	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1081093001290	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1081093001291	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1081093001292	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1081093001293	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1081093001294	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1081093001295	Hexamer interface [polypeptide binding]; other site
1081093001296	Putative hexagonal pore residue; other site
1081093001297	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1081093001298	putative catalytic cysteine [active]
1081093001299	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1081093001300	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1081093001301	active site
1081093001302	metal binding site [ion binding]; metal-binding site
1081093001303	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1081093001304	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1081093001305	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1081093001306	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1081093001307	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1081093001308	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1081093001309	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1081093001310	putative hexamer interface [polypeptide binding]; other site
1081093001311	putative hexagonal pore; other site
1081093001312	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1081093001313	putative hexamer interface [polypeptide binding]; other site
1081093001314	putative hexagonal pore; other site
1081093001315	carboxysome structural protein EutK; Provisional; Region: PRK15466
1081093001316	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1081093001317	Hexamer interface [polypeptide binding]; other site
1081093001318	Hexagonal pore residue; other site
1081093001319	transcriptional regulator EutR; Provisional; Region: PRK10130
1081093001320	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093001321	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093001322	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1081093001323	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1081093001324	active site
1081093001325	metal binding site [ion binding]; metal-binding site
1081093001326	putative acetyltransferase; Provisional; Region: PRK03624
1081093001327	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093001328	Coenzyme A binding pocket [chemical binding]; other site
1081093001329	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1081093001330	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1081093001331	short chain dehydrogenase; Provisional; Region: PRK08226
1081093001332	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1081093001333	NAD binding site [chemical binding]; other site
1081093001334	homotetramer interface [polypeptide binding]; other site
1081093001335	homodimer interface [polypeptide binding]; other site
1081093001336	active site
1081093001337	thiosulfate transporter subunit; Provisional; Region: PRK10852
1081093001338	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1081093001339	sulfate transport protein; Provisional; Region: cysT; CHL00187
1081093001340	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093001341	dimer interface [polypeptide binding]; other site
1081093001342	conserved gate region; other site
1081093001343	putative PBP binding loops; other site
1081093001344	ABC-ATPase subunit interface; other site
1081093001345	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1081093001346	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1081093001347	Walker A/P-loop; other site
1081093001348	ATP binding site [chemical binding]; other site
1081093001349	Q-loop/lid; other site
1081093001350	ABC transporter signature motif; other site
1081093001351	Walker B; other site
1081093001352	D-loop; other site
1081093001353	H-loop/switch region; other site
1081093001354	TOBE-like domain; Region: TOBE_3; pfam12857
1081093001355	cysteine synthase B; Region: cysM; TIGR01138
1081093001356	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1081093001357	dimer interface [polypeptide binding]; other site
1081093001358	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093001359	catalytic residue [active]
1081093001360	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1081093001361	Sel1-like repeats; Region: SEL1; smart00671
1081093001362	hypothetical protein; Provisional; Region: PRK10318
1081093001363	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1081093001364	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1081093001365	catalytic triad [active]
1081093001366	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
1081093001367	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093001368	DNA-binding site [nucleotide binding]; DNA binding site
1081093001369	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093001370	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093001371	homodimer interface [polypeptide binding]; other site
1081093001372	catalytic residue [active]
1081093001373	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1081093001374	dimer interface [polypeptide binding]; other site
1081093001375	pyridoxamine kinase; Validated; Region: PRK05756
1081093001376	pyridoxal binding site [chemical binding]; other site
1081093001377	ATP binding site [chemical binding]; other site
1081093001378	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1081093001379	HPr interaction site; other site
1081093001380	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1081093001381	active site
1081093001382	phosphorylation site [posttranslational modification]
1081093001383	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1081093001384	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1081093001385	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1081093001386	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1081093001387	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1081093001388	dimerization domain swap beta strand [polypeptide binding]; other site
1081093001389	regulatory protein interface [polypeptide binding]; other site
1081093001390	active site
1081093001391	regulatory phosphorylation site [posttranslational modification]; other site
1081093001392	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1081093001393	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1081093001394	dimer interface [polypeptide binding]; other site
1081093001395	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093001396	catalytic residue [active]
1081093001397	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1081093001398	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1081093001399	cell division protein ZipA; Provisional; Region: PRK03427
1081093001400	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1081093001401	FtsZ protein binding site [polypeptide binding]; other site
1081093001402	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1081093001403	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1081093001404	nucleotide binding pocket [chemical binding]; other site
1081093001405	K-X-D-G motif; other site
1081093001406	catalytic site [active]
1081093001407	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1081093001408	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1081093001409	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; cl17855
1081093001410	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1081093001411	Dimer interface [polypeptide binding]; other site
1081093001412	BRCT sequence motif; other site
1081093001413	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1081093001414	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1081093001415	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1081093001416	hypothetical protein; Provisional; Region: PRK11528
1081093001417	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1081093001418	nucleoside transporter; Region: 2A0110; TIGR00889
1081093001419	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093001420	putative substrate translocation pore; other site
1081093001421	XapX domain; Region: XapX; TIGR03510
1081093001422	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1081093001423	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093001424	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
1081093001425	putative dimerization interface [polypeptide binding]; other site
1081093001426	putative substrate binding pocket [chemical binding]; other site
1081093001427	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1081093001428	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1081093001429	active site
1081093001430	HIGH motif; other site
1081093001431	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1081093001432	active site
1081093001433	KMSKS motif; other site
1081093001434	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1081093001435	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1081093001436	MASE1; Region: MASE1; pfam05231
1081093001437	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1081093001438	diguanylate cyclase; Region: GGDEF; smart00267
1081093001439	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093001440	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1081093001441	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1081093001442	Nucleoside recognition; Region: Gate; pfam07670
1081093001443	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1081093001444	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1081093001445	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093001446	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093001447	active site
1081093001448	catalytic tetrad [active]
1081093001449	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
1081093001450	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1081093001451	dimer interface [polypeptide binding]; other site
1081093001452	PYR/PP interface [polypeptide binding]; other site
1081093001453	TPP binding site [chemical binding]; other site
1081093001454	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1081093001455	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1081093001456	TPP-binding site [chemical binding]; other site
1081093001457	dimer interface [polypeptide binding]; other site
1081093001458	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1081093001459	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1081093001460	Cl- selectivity filter; other site
1081093001461	Cl- binding residues [ion binding]; other site
1081093001462	pore gating glutamate residue; other site
1081093001463	dimer interface [polypeptide binding]; other site
1081093001464	glucokinase; Provisional; Region: glk; PRK00292
1081093001465	glucokinase, proteobacterial type; Region: glk; TIGR00749
1081093001466	aminotransferase; Validated; Region: PRK08175
1081093001467	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093001468	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093001469	homodimer interface [polypeptide binding]; other site
1081093001470	catalytic residue [active]
1081093001471	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1081093001472	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1081093001473	putative acyl-acceptor binding pocket; other site
1081093001474	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
1081093001475	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1081093001476	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1081093001477	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
1081093001478	HAMP domain; Region: HAMP; pfam00672
1081093001479	dimerization interface [polypeptide binding]; other site
1081093001480	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093001481	dimer interface [polypeptide binding]; other site
1081093001482	phosphorylation site [posttranslational modification]
1081093001483	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093001484	ATP binding site [chemical binding]; other site
1081093001485	Mg2+ binding site [ion binding]; other site
1081093001486	G-X-G motif; other site
1081093001487	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1081093001488	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093001489	active site
1081093001490	phosphorylation site [posttranslational modification]
1081093001491	intermolecular recognition site; other site
1081093001492	dimerization interface [polypeptide binding]; other site
1081093001493	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1081093001494	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1081093001495	outer membrane protease; Reviewed; Region: PRK10993
1081093001496	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1081093001497	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1081093001498	GtrA-like protein; Region: GtrA; pfam04138
1081093001499	Predicted membrane protein [Function unknown]; Region: COG2246
1081093001500	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1081093001501	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1081093001502	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1081093001503	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1081093001504	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1081093001505	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1081093001506	dimer interface [polypeptide binding]; other site
1081093001507	active site
1081093001508	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1081093001509	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1081093001510	substrate binding site [chemical binding]; other site
1081093001511	oxyanion hole (OAH) forming residues; other site
1081093001512	trimer interface [polypeptide binding]; other site
1081093001513	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1081093001514	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1081093001515	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1081093001516	catalytic core [active]
1081093001517	hypothetical protein; Provisional; Region: PRK04946
1081093001518	Smr domain; Region: Smr; pfam01713
1081093001519	HemK family putative methylases; Region: hemK_fam; TIGR00536
1081093001520	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093001521	S-adenosylmethionine binding site [chemical binding]; other site
1081093001522	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1081093001523	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1081093001524	Tetramer interface [polypeptide binding]; other site
1081093001525	active site
1081093001526	FMN-binding site [chemical binding]; other site
1081093001527	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1081093001528	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1081093001529	hypothetical protein; Provisional; Region: PRK10621
1081093001530	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1081093001531	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1081093001532	YfcL protein; Region: YfcL; pfam08891
1081093001533	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1081093001534	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1081093001535	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1081093001536	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1081093001537	dimer interface [polypeptide binding]; other site
1081093001538	active site
1081093001539	CAAX protease self-immunity; Region: Abi; pfam02517
1081093001540	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1081093001541	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093001542	non-specific DNA binding site [nucleotide binding]; other site
1081093001543	salt bridge; other site
1081093001544	sequence-specific DNA binding site [nucleotide binding]; other site
1081093001545	putative transporter; Provisional; Region: PRK12382
1081093001546	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093001547	putative substrate translocation pore; other site
1081093001548	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1081093001549	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1081093001550	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1081093001551	ligand binding site [chemical binding]; other site
1081093001552	NAD binding site [chemical binding]; other site
1081093001553	catalytic site [active]
1081093001554	homodimer interface [polypeptide binding]; other site
1081093001555	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1081093001556	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1081093001557	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
1081093001558	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1081093001559	dimerization interface 3.5A [polypeptide binding]; other site
1081093001560	active site
1081093001561	hypothetical protein; Provisional; Region: PRK10847
1081093001562	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1081093001563	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1081093001564	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1081093001565	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1081093001566	cell division protein DedD; Provisional; Region: PRK11633
1081093001567	Sporulation related domain; Region: SPOR; pfam05036
1081093001568	colicin V production protein; Provisional; Region: PRK10845
1081093001569	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1081093001570	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1081093001571	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1081093001572	active site
1081093001573	tetramer interface [polypeptide binding]; other site
1081093001574	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1081093001575	active site
1081093001576	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1081093001577	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1081093001578	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1081093001579	catalytic residue [active]
1081093001580	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
1081093001581	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
1081093001582	dimer interface [polypeptide binding]; other site
1081093001583	active site
1081093001584	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1081093001585	substrate binding site [chemical binding]; other site
1081093001586	catalytic residue [active]
1081093001587	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1081093001588	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1081093001589	Flavoprotein; Region: Flavoprotein; pfam02441
1081093001590	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1081093001591	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093001592	substrate binding pocket [chemical binding]; other site
1081093001593	membrane-bound complex binding site; other site
1081093001594	hinge residues; other site
1081093001595	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1081093001596	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093001597	dimer interface [polypeptide binding]; other site
1081093001598	conserved gate region; other site
1081093001599	putative PBP binding loops; other site
1081093001600	ABC-ATPase subunit interface; other site
1081093001601	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1081093001602	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093001603	dimer interface [polypeptide binding]; other site
1081093001604	conserved gate region; other site
1081093001605	putative PBP binding loops; other site
1081093001606	ABC-ATPase subunit interface; other site
1081093001607	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1081093001608	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1081093001609	Walker A/P-loop; other site
1081093001610	ATP binding site [chemical binding]; other site
1081093001611	Q-loop/lid; other site
1081093001612	ABC transporter signature motif; other site
1081093001613	Walker B; other site
1081093001614	D-loop; other site
1081093001615	H-loop/switch region; other site
1081093001616	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1081093001617	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1081093001618	putative NAD(P) binding site [chemical binding]; other site
1081093001619	putative active site [active]
1081093001620	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1081093001621	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1081093001622	C-terminal domain interface [polypeptide binding]; other site
1081093001623	GSH binding site (G-site) [chemical binding]; other site
1081093001624	dimer interface [polypeptide binding]; other site
1081093001625	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1081093001626	N-terminal domain interface [polypeptide binding]; other site
1081093001627	putative dimer interface [polypeptide binding]; other site
1081093001628	active site
1081093001629	glutathione S-transferase; Provisional; Region: PRK15113
1081093001630	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1081093001631	C-terminal domain interface [polypeptide binding]; other site
1081093001632	GSH binding site (G-site) [chemical binding]; other site
1081093001633	dimer interface [polypeptide binding]; other site
1081093001634	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1081093001635	N-terminal domain interface [polypeptide binding]; other site
1081093001636	putative dimer interface [polypeptide binding]; other site
1081093001637	putative substrate binding pocket (H-site) [chemical binding]; other site
1081093001638	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1081093001639	active site
1081093001640	metal binding site [ion binding]; metal-binding site
1081093001641	homotetramer interface [polypeptide binding]; other site
1081093001642	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1081093001643	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1081093001644	nudix motif; other site
1081093001645	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1081093001646	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093001647	DNA binding site [nucleotide binding]
1081093001648	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1081093001649	putative dimerization interface [polypeptide binding]; other site
1081093001650	putative ligand binding site [chemical binding]; other site
1081093001651	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1081093001652	active site
1081093001653	phosphorylation site [posttranslational modification]
1081093001654	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1081093001655	active site
1081093001656	P-loop; other site
1081093001657	phosphorylation site [posttranslational modification]
1081093001658	transketolase; Reviewed; Region: PRK05899
1081093001659	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1081093001660	TPP-binding site [chemical binding]; other site
1081093001661	dimer interface [polypeptide binding]; other site
1081093001662	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1081093001663	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1081093001664	PYR/PP interface [polypeptide binding]; other site
1081093001665	dimer interface [polypeptide binding]; other site
1081093001666	TPP binding site [chemical binding]; other site
1081093001667	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1081093001668	phosphate acetyltransferase; Reviewed; Region: PRK05632
1081093001669	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1081093001670	DRTGG domain; Region: DRTGG; pfam07085
1081093001671	phosphate acetyltransferase; Region: pta; TIGR00651
1081093001672	propionate/acetate kinase; Provisional; Region: PRK12379
1081093001673	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1081093001674	hypothetical protein; Provisional; Region: PRK01816
1081093001675	hypothetical protein; Validated; Region: PRK05445
1081093001676	putative phosphatase; Provisional; Region: PRK11587
1081093001677	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093001678	motif II; other site
1081093001679	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1081093001680	transmembrane helices; other site
1081093001681	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1081093001682	TrkA-C domain; Region: TrkA_C; pfam02080
1081093001683	TrkA-C domain; Region: TrkA_C; pfam02080
1081093001684	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1081093001685	5'-nucleotidase; Provisional; Region: PRK03826
1081093001686	aminotransferase AlaT; Validated; Region: PRK09265
1081093001687	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093001688	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093001689	homodimer interface [polypeptide binding]; other site
1081093001690	catalytic residue [active]
1081093001691	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1081093001692	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093001693	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1081093001694	putative dimerization interface [polypeptide binding]; other site
1081093001695	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1081093001696	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1081093001697	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1081093001698	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1081093001699	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1081093001700	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1081093001701	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1081093001702	putative dimer interface [polypeptide binding]; other site
1081093001703	[2Fe-2S] cluster binding site [ion binding]; other site
1081093001704	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1081093001705	SLBB domain; Region: SLBB; pfam10531
1081093001706	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1081093001707	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1081093001708	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1081093001709	catalytic loop [active]
1081093001710	iron binding site [ion binding]; other site
1081093001711	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1081093001712	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1081093001713	[4Fe-4S] binding site [ion binding]; other site
1081093001714	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1081093001715	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1081093001716	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1081093001717	4Fe-4S binding domain; Region: Fer4; pfam00037
1081093001718	4Fe-4S binding domain; Region: Fer4; pfam00037
1081093001719	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1081093001720	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1081093001721	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1081093001722	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1081093001723	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1081093001724	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1081093001725	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1081093001726	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1081093001727	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1081093001728	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1081093001729	von Willebrand factor; Region: vWF_A; pfam12450
1081093001730	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
1081093001731	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
1081093001732	metal ion-dependent adhesion site (MIDAS); other site
1081093001733	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
1081093001734	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1081093001735	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1081093001736	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093001737	active site
1081093001738	phosphorylation site [posttranslational modification]
1081093001739	intermolecular recognition site; other site
1081093001740	dimerization interface [polypeptide binding]; other site
1081093001741	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093001742	Coenzyme A binding pocket [chemical binding]; other site
1081093001743	hypothetical protein; Provisional; Region: PRK10404
1081093001744	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1081093001745	isochorismate synthases; Region: isochor_syn; TIGR00543
1081093001746	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1081093001747	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1081093001748	dimer interface [polypeptide binding]; other site
1081093001749	tetramer interface [polypeptide binding]; other site
1081093001750	PYR/PP interface [polypeptide binding]; other site
1081093001751	TPP binding site [chemical binding]; other site
1081093001752	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1081093001753	TPP-binding site; other site
1081093001754	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1081093001755	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1081093001756	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1081093001757	substrate binding site [chemical binding]; other site
1081093001758	oxyanion hole (OAH) forming residues; other site
1081093001759	trimer interface [polypeptide binding]; other site
1081093001760	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
1081093001761	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1081093001762	active site
1081093001763	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1081093001764	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1081093001765	acyl-activating enzyme (AAE) consensus motif; other site
1081093001766	putative AMP binding site [chemical binding]; other site
1081093001767	putative active site [active]
1081093001768	putative CoA binding site [chemical binding]; other site
1081093001769	signal transduction protein PmrD; Provisional; Region: PRK15450
1081093001770	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1081093001771	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1081093001772	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1081093001773	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1081093001774	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1081093001775	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1081093001776	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1081093001777	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1081093001778	active site
1081093001779	substrate binding site [chemical binding]; other site
1081093001780	cosubstrate binding site; other site
1081093001781	catalytic site [active]
1081093001782	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1081093001783	active site
1081093001784	hexamer interface [polypeptide binding]; other site
1081093001785	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1081093001786	NAD binding site [chemical binding]; other site
1081093001787	substrate binding site [chemical binding]; other site
1081093001788	active site
1081093001789	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1081093001790	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1081093001791	Ligand binding site; other site
1081093001792	Putative Catalytic site; other site
1081093001793	DXD motif; other site
1081093001794	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1081093001795	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1081093001796	inhibitor-cofactor binding pocket; inhibition site
1081093001797	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093001798	catalytic residue [active]
1081093001799	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1081093001800	catalytic core [active]
1081093001801	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1081093001802	YfaZ precursor; Region: YfaZ; pfam07437
1081093001803	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
1081093001804	hypothetical protein; Provisional; Region: PRK03673
1081093001805	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1081093001806	putative MPT binding site; other site
1081093001807	Competence-damaged protein; Region: CinA; cl00666
1081093001808	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1081093001809	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1081093001810	Bacterial transcriptional regulator; Region: IclR; pfam01614
1081093001811	L-rhamnonate dehydratase; Provisional; Region: PRK15440
1081093001812	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
1081093001813	putative active site pocket [active]
1081093001814	putative metal binding site [ion binding]; other site
1081093001815	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
1081093001816	hypothetical protein; Provisional; Region: PRK03673
1081093001817	deubiquitinase SseL; Provisional; Region: PRK14848
1081093001818	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1081093001819	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1081093001820	Cysteine-rich domain; Region: CCG; pfam02754
1081093001821	Cysteine-rich domain; Region: CCG; pfam02754
1081093001822	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1081093001823	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1081093001824	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1081093001825	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1081093001826	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1081093001827	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1081093001828	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093001829	putative substrate translocation pore; other site
1081093001830	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1081093001831	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1081093001832	active site
1081093001833	catalytic site [active]
1081093001834	metal binding site [ion binding]; metal-binding site
1081093001835	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1081093001836	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093001837	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1081093001838	dimerization interface [polypeptide binding]; other site
1081093001839	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1081093001840	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093001841	putative substrate translocation pore; other site
1081093001842	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1081093001843	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1081093001844	catalytic loop [active]
1081093001845	iron binding site [ion binding]; other site
1081093001846	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1081093001847	dimer interface [polypeptide binding]; other site
1081093001848	putative radical transfer pathway; other site
1081093001849	diiron center [ion binding]; other site
1081093001850	tyrosyl radical; other site
1081093001851	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1081093001852	ATP cone domain; Region: ATP-cone; pfam03477
1081093001853	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1081093001854	active site
1081093001855	dimer interface [polypeptide binding]; other site
1081093001856	catalytic residues [active]
1081093001857	effector binding site; other site
1081093001858	R2 peptide binding site; other site
1081093001859	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1081093001860	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093001861	S-adenosylmethionine binding site [chemical binding]; other site
1081093001862	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1081093001863	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093001864	DNA-binding site [nucleotide binding]; DNA binding site
1081093001865	FCD domain; Region: FCD; pfam07729
1081093001866	DNA gyrase subunit A; Validated; Region: PRK05560
1081093001867	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1081093001868	CAP-like domain; other site
1081093001869	active site
1081093001870	primary dimer interface [polypeptide binding]; other site
1081093001871	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1081093001872	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1081093001873	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1081093001874	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1081093001875	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1081093001876	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1081093001877	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1081093001878	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093001879	dimer interface [polypeptide binding]; other site
1081093001880	phosphorylation site [posttranslational modification]
1081093001881	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093001882	ATP binding site [chemical binding]; other site
1081093001883	Mg2+ binding site [ion binding]; other site
1081093001884	G-X-G motif; other site
1081093001885	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1081093001886	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093001887	transcriptional regulator RcsB; Provisional; Region: PRK10840
1081093001888	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093001889	active site
1081093001890	phosphorylation site [posttranslational modification]
1081093001891	intermolecular recognition site; other site
1081093001892	dimerization interface [polypeptide binding]; other site
1081093001893	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093001894	DNA binding residues [nucleotide binding]
1081093001895	dimerization interface [polypeptide binding]; other site
1081093001896	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1081093001897	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093001898	ATP binding site [chemical binding]; other site
1081093001899	G-X-G motif; other site
1081093001900	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1081093001901	putative binding surface; other site
1081093001902	active site
1081093001903	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1081093001904	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1081093001905	trimer interface [polypeptide binding]; other site
1081093001906	eyelet of channel; other site
1081093001907	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1081093001908	ApbE family; Region: ApbE; pfam02424
1081093001909	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1081093001910	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1081093001911	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093001912	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1081093001913	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1081093001914	DNA binding site [nucleotide binding]
1081093001915	active site
1081093001916	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1081093001917	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1081093001918	Walker A/P-loop; other site
1081093001919	ATP binding site [chemical binding]; other site
1081093001920	Q-loop/lid; other site
1081093001921	ABC transporter signature motif; other site
1081093001922	Walker B; other site
1081093001923	D-loop; other site
1081093001924	H-loop/switch region; other site
1081093001925	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1081093001926	secondary substrate binding site; other site
1081093001927	primary substrate binding site; other site
1081093001928	inhibition loop; other site
1081093001929	dimerization interface [polypeptide binding]; other site
1081093001930	ferredoxin-type protein; Provisional; Region: PRK10194
1081093001931	4Fe-4S binding domain; Region: Fer4; cl02805
1081093001932	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1081093001933	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1081093001934	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1081093001935	[4Fe-4S] binding site [ion binding]; other site
1081093001936	molybdopterin cofactor binding site; other site
1081093001937	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1081093001938	molybdopterin cofactor binding site; other site
1081093001939	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1081093001940	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1081093001941	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1081093001942	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1081093001943	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1081093001944	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1081093001945	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1081093001946	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093001947	Walker A/P-loop; other site
1081093001948	ATP binding site [chemical binding]; other site
1081093001949	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093001950	H-loop/switch region; other site
1081093001951	heme exporter protein CcmB; Region: ccmB; TIGR01190
1081093001952	heme exporter protein CcmC; Region: ccmC; TIGR01191
1081093001953	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1081093001954	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1081093001955	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1081093001956	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1081093001957	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1081093001958	catalytic residues [active]
1081093001959	central insert; other site
1081093001960	transcriptional regulator NarP; Provisional; Region: PRK10403
1081093001961	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093001962	active site
1081093001963	phosphorylation site [posttranslational modification]
1081093001964	intermolecular recognition site; other site
1081093001965	dimerization interface [polypeptide binding]; other site
1081093001966	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093001967	DNA binding residues [nucleotide binding]
1081093001968	dimerization interface [polypeptide binding]; other site
1081093001969	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
1081093001970	DinI-like family; Region: DinI; cl11630
1081093001971	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1081093001972	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1081093001973	Sulfatase; Region: Sulfatase; cl17466
1081093001974	hypothetical protein; Provisional; Region: PRK13689
1081093001975	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1081093001976	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1081093001977	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1081093001978	5S rRNA interface [nucleotide binding]; other site
1081093001979	CTC domain interface [polypeptide binding]; other site
1081093001980	L16 interface [polypeptide binding]; other site
1081093001981	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1081093001982	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1081093001983	ATP binding site [chemical binding]; other site
1081093001984	putative Mg++ binding site [ion binding]; other site
1081093001985	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093001986	nucleotide binding region [chemical binding]; other site
1081093001987	ATP-binding site [chemical binding]; other site
1081093001988	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1081093001989	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1081093001990	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1081093001991	RNA binding surface [nucleotide binding]; other site
1081093001992	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1081093001993	active site
1081093001994	uracil binding [chemical binding]; other site
1081093001995	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093001996	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1081093001997	putative substrate translocation pore; other site
1081093001998	hypothetical protein; Provisional; Region: PRK11835
1081093001999	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1081093002000	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093002001	Walker A/P-loop; other site
1081093002002	ATP binding site [chemical binding]; other site
1081093002003	Q-loop/lid; other site
1081093002004	ABC transporter signature motif; other site
1081093002005	Walker B; other site
1081093002006	D-loop; other site
1081093002007	H-loop/switch region; other site
1081093002008	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1081093002009	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093002010	Walker A/P-loop; other site
1081093002011	ATP binding site [chemical binding]; other site
1081093002012	Q-loop/lid; other site
1081093002013	ABC transporter signature motif; other site
1081093002014	Walker B; other site
1081093002015	D-loop; other site
1081093002016	H-loop/switch region; other site
1081093002017	microcin C ABC transporter permease; Provisional; Region: PRK15021
1081093002018	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093002019	dimer interface [polypeptide binding]; other site
1081093002020	conserved gate region; other site
1081093002021	ABC-ATPase subunit interface; other site
1081093002022	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1081093002023	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093002024	dimer interface [polypeptide binding]; other site
1081093002025	conserved gate region; other site
1081093002026	putative PBP binding loops; other site
1081093002027	ABC-ATPase subunit interface; other site
1081093002028	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1081093002029	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1081093002030	phage resistance protein; Provisional; Region: PRK10551
1081093002031	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1081093002032	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093002033	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1081093002034	NlpC/P60 family; Region: NLPC_P60; pfam00877
1081093002035	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1081093002036	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1081093002037	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1081093002038	elongation factor P; Provisional; Region: PRK04542
1081093002039	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1081093002040	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1081093002041	RNA binding site [nucleotide binding]; other site
1081093002042	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1081093002043	RNA binding site [nucleotide binding]; other site
1081093002044	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1081093002045	sugar efflux transporter B; Provisional; Region: PRK15011
1081093002046	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093002047	putative substrate translocation pore; other site
1081093002048	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1081093002049	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1081093002050	active site
1081093002051	phosphorylation site [posttranslational modification]
1081093002052	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1081093002053	dimerization domain swap beta strand [polypeptide binding]; other site
1081093002054	regulatory protein interface [polypeptide binding]; other site
1081093002055	active site
1081093002056	regulatory phosphorylation site [posttranslational modification]; other site
1081093002057	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1081093002058	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1081093002059	putative substrate binding site [chemical binding]; other site
1081093002060	putative ATP binding site [chemical binding]; other site
1081093002061	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1081093002062	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1081093002063	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1081093002064	active site
1081093002065	P-loop; other site
1081093002066	phosphorylation site [posttranslational modification]
1081093002067	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1081093002068	endonuclease IV; Provisional; Region: PRK01060
1081093002069	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1081093002070	AP (apurinic/apyrimidinic) site pocket; other site
1081093002071	DNA interaction; other site
1081093002072	Metal-binding active site; metal-binding site
1081093002073	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1081093002074	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1081093002075	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093002076	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1081093002077	putative dimerization interface [polypeptide binding]; other site
1081093002078	lysine transporter; Provisional; Region: PRK10836
1081093002079	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1081093002080	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1081093002081	N-terminal plug; other site
1081093002082	ligand-binding site [chemical binding]; other site
1081093002083	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1081093002084	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093002085	putative substrate translocation pore; other site
1081093002086	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1081093002087	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1081093002088	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093002089	motif II; other site
1081093002090	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1081093002091	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1081093002092	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1081093002093	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1081093002094	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093002095	non-specific DNA binding site [nucleotide binding]; other site
1081093002096	salt bridge; other site
1081093002097	sequence-specific DNA binding site [nucleotide binding]; other site
1081093002098	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1081093002099	S-formylglutathione hydrolase; Region: PLN02442
1081093002100	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1081093002101	GTP cyclohydrolase I; Provisional; Region: PLN03044
1081093002102	active site
1081093002103	Predicted membrane protein [Function unknown]; Region: COG2311
1081093002104	hypothetical protein; Provisional; Region: PRK10835
1081093002105	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1081093002106	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093002107	DNA binding site [nucleotide binding]
1081093002108	domain linker motif; other site
1081093002109	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1081093002110	dimerization interface (closed form) [polypeptide binding]; other site
1081093002111	ligand binding site [chemical binding]; other site
1081093002112	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1081093002113	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1081093002114	ligand binding site [chemical binding]; other site
1081093002115	calcium binding site [ion binding]; other site
1081093002116	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1081093002117	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1081093002118	TM-ABC transporter signature motif; other site
1081093002119	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
1081093002120	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
1081093002121	homodimer interface [polypeptide binding]; other site
1081093002122	active site
1081093002123	FMN binding site [chemical binding]; other site
1081093002124	substrate binding site [chemical binding]; other site
1081093002125	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1081093002126	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1081093002127	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093002128	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
1081093002129	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1081093002130	putative active site [active]
1081093002131	cytidine deaminase; Provisional; Region: PRK09027
1081093002132	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1081093002133	active site
1081093002134	catalytic motif [active]
1081093002135	Zn binding site [ion binding]; other site
1081093002136	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1081093002137	active site
1081093002138	catalytic motif [active]
1081093002139	Zn binding site [ion binding]; other site
1081093002140	hypothetical protein; Provisional; Region: PRK10711
1081093002141	hypothetical protein; Provisional; Region: PRK01821
1081093002142	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093002143	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093002144	dimerization interface [polypeptide binding]; other site
1081093002145	benzoate transport; Region: 2A0115; TIGR00895
1081093002146	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093002147	putative substrate translocation pore; other site
1081093002148	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
1081093002149	Cupin domain; Region: Cupin_2; pfam07883
1081093002150	Cupin domain; Region: Cupin_2; pfam07883
1081093002151	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1081093002152	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1081093002153	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
1081093002154	maleylacetoacetate isomerase; Region: maiA; TIGR01262
1081093002155	C-terminal domain interface [polypeptide binding]; other site
1081093002156	GSH binding site (G-site) [chemical binding]; other site
1081093002157	putative dimer interface [polypeptide binding]; other site
1081093002158	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
1081093002159	dimer interface [polypeptide binding]; other site
1081093002160	N-terminal domain interface [polypeptide binding]; other site
1081093002161	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
1081093002162	salicylate hydroxylase; Provisional; Region: PRK08163
1081093002163	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1081093002164	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1081093002165	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1081093002166	FMN binding site [chemical binding]; other site
1081093002167	active site
1081093002168	catalytic residues [active]
1081093002169	substrate binding site [chemical binding]; other site
1081093002170	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
1081093002171	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1081093002172	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1081093002173	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1081093002174	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1081093002175	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1081093002176	D-lactate dehydrogenase; Provisional; Region: PRK11183
1081093002177	FAD binding domain; Region: FAD_binding_4; pfam01565
1081093002178	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1081093002179	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1081093002180	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1081093002181	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1081093002182	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1081093002183	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093002184	dimer interface [polypeptide binding]; other site
1081093002185	conserved gate region; other site
1081093002186	ABC-ATPase subunit interface; other site
1081093002187	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1081093002188	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1081093002189	Walker A/P-loop; other site
1081093002190	ATP binding site [chemical binding]; other site
1081093002191	Q-loop/lid; other site
1081093002192	ABC transporter signature motif; other site
1081093002193	Walker B; other site
1081093002194	D-loop; other site
1081093002195	H-loop/switch region; other site
1081093002196	CBS domain; Region: CBS; pfam00571
1081093002197	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
1081093002198	putative PBP binding loops; other site
1081093002199	ABC-ATPase subunit interface; other site
1081093002200	transcriptional regulator MirA; Provisional; Region: PRK15043
1081093002201	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1081093002202	DNA binding residues [nucleotide binding]
1081093002203	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1081093002204	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1081093002205	GAF domain; Region: GAF; pfam01590
1081093002206	Histidine kinase; Region: His_kinase; pfam06580
1081093002207	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093002208	ATP binding site [chemical binding]; other site
1081093002209	Mg2+ binding site [ion binding]; other site
1081093002210	G-X-G motif; other site
1081093002211	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1081093002212	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093002213	active site
1081093002214	phosphorylation site [posttranslational modification]
1081093002215	intermolecular recognition site; other site
1081093002216	dimerization interface [polypeptide binding]; other site
1081093002217	LytTr DNA-binding domain; Region: LytTR; pfam04397
1081093002218	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1081093002219	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1081093002220	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1081093002221	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1081093002222	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1081093002223	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1081093002224	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1081093002225	active site
1081093002226	HIGH motif; other site
1081093002227	KMSKS motif; other site
1081093002228	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1081093002229	tRNA binding surface [nucleotide binding]; other site
1081093002230	anticodon binding site; other site
1081093002231	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1081093002232	dimer interface [polypeptide binding]; other site
1081093002233	putative tRNA-binding site [nucleotide binding]; other site
1081093002234	antiporter inner membrane protein; Provisional; Region: PRK11670
1081093002235	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1081093002236	Walker A motif; other site
1081093002237	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
1081093002238	fimbrial chaperone protein; Provisional; Region: PRK15220
1081093002239	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
1081093002240	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093002241	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
1081093002242	PapC N-terminal domain; Region: PapC_N; pfam13954
1081093002243	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1081093002244	PapC C-terminal domain; Region: PapC_C; pfam13953
1081093002245	Predicted integral membrane protein [Function unknown]; Region: COG5455
1081093002246	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1081093002247	substrate binding site [chemical binding]; other site
1081093002248	multimerization interface [polypeptide binding]; other site
1081093002249	ATP binding site [chemical binding]; other site
1081093002250	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1081093002251	dimer interface [polypeptide binding]; other site
1081093002252	substrate binding site [chemical binding]; other site
1081093002253	ATP binding site [chemical binding]; other site
1081093002254	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1081093002255	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093002256	DNA-binding site [nucleotide binding]; DNA binding site
1081093002257	UTRA domain; Region: UTRA; pfam07702
1081093002258	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093002259	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1081093002260	substrate binding site [chemical binding]; other site
1081093002261	ATP binding site [chemical binding]; other site
1081093002262	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1081093002263	nucleoside transporter; Region: 2A0110; TIGR00889
1081093002264	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093002265	putative substrate translocation pore; other site
1081093002266	lipid kinase; Reviewed; Region: PRK13054
1081093002267	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1081093002268	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
1081093002269	putative protease; Provisional; Region: PRK15452
1081093002270	Peptidase family U32; Region: Peptidase_U32; pfam01136
1081093002271	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
1081093002272	PcfJ-like protein; Region: PcfJ; pfam14284
1081093002273	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1081093002274	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093002275	active site
1081093002276	phosphorylation site [posttranslational modification]
1081093002277	intermolecular recognition site; other site
1081093002278	dimerization interface [polypeptide binding]; other site
1081093002279	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093002280	DNA binding site [nucleotide binding]
1081093002281	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1081093002282	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093002283	dimerization interface [polypeptide binding]; other site
1081093002284	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093002285	dimer interface [polypeptide binding]; other site
1081093002286	phosphorylation site [posttranslational modification]
1081093002287	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093002288	ATP binding site [chemical binding]; other site
1081093002289	Mg2+ binding site [ion binding]; other site
1081093002290	G-X-G motif; other site
1081093002291	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1081093002292	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1081093002293	Protein export membrane protein; Region: SecD_SecF; cl14618
1081093002294	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1081093002295	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1081093002296	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093002297	putative chaperone; Provisional; Region: PRK11678
1081093002298	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1081093002299	nucleotide binding site [chemical binding]; other site
1081093002300	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1081093002301	SBD interface [polypeptide binding]; other site
1081093002302	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1081093002303	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1081093002304	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1081093002305	minor groove reading motif; other site
1081093002306	helix-hairpin-helix signature motif; other site
1081093002307	substrate binding pocket [chemical binding]; other site
1081093002308	active site
1081093002309	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1081093002310	PAS domain S-box; Region: sensory_box; TIGR00229
1081093002311	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1081093002312	putative active site [active]
1081093002313	heme pocket [chemical binding]; other site
1081093002314	PAS domain S-box; Region: sensory_box; TIGR00229
1081093002315	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1081093002316	putative active site [active]
1081093002317	heme pocket [chemical binding]; other site
1081093002318	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1081093002319	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093002320	metal binding site [ion binding]; metal-binding site
1081093002321	active site
1081093002322	I-site; other site
1081093002323	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093002324	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1081093002325	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1081093002326	ATP-binding site [chemical binding]; other site
1081093002327	Sugar specificity; other site
1081093002328	Pyrimidine base specificity; other site
1081093002329	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1081093002330	trimer interface [polypeptide binding]; other site
1081093002331	active site
1081093002332	putative assembly protein; Provisional; Region: PRK10833
1081093002333	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1081093002334	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1081093002335	FOG: CBS domain [General function prediction only]; Region: COG0517
1081093002336	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1081093002337	Transporter associated domain; Region: CorC_HlyC; smart01091
1081093002338	polysaccharide export protein Wza; Provisional; Region: PRK15078
1081093002339	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1081093002340	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1081093002341	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1081093002342	active site
1081093002343	tyrosine kinase; Provisional; Region: PRK11519
1081093002344	Chain length determinant protein; Region: Wzz; pfam02706
1081093002345	Chain length determinant protein; Region: Wzz; cl15801
1081093002346	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1081093002347	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1081093002348	putative glycosyl transferase; Provisional; Region: PRK10018
1081093002349	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1081093002350	active site
1081093002351	putative acyl transferase; Provisional; Region: PRK10191
1081093002352	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1081093002353	trimer interface [polypeptide binding]; other site
1081093002354	active site
1081093002355	substrate binding site [chemical binding]; other site
1081093002356	CoA binding site [chemical binding]; other site
1081093002357	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1081093002358	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1081093002359	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1081093002360	putative glycosyl transferase; Provisional; Region: PRK10063
1081093002361	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1081093002362	metal-binding site
1081093002363	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1081093002364	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1081093002365	putative trimer interface [polypeptide binding]; other site
1081093002366	putative active site [active]
1081093002367	putative substrate binding site [chemical binding]; other site
1081093002368	putative CoA binding site [chemical binding]; other site
1081093002369	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1081093002370	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1081093002371	NADP-binding site; other site
1081093002372	homotetramer interface [polypeptide binding]; other site
1081093002373	substrate binding site [chemical binding]; other site
1081093002374	homodimer interface [polypeptide binding]; other site
1081093002375	active site
1081093002376	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1081093002377	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1081093002378	NADP binding site [chemical binding]; other site
1081093002379	active site
1081093002380	putative substrate binding site [chemical binding]; other site
1081093002381	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1081093002382	active site
1081093002383	GDP-Mannose binding site [chemical binding]; other site
1081093002384	dimer interface [polypeptide binding]; other site
1081093002385	modified nudix motif
1081093002386	metal binding site [ion binding]; metal-binding site
1081093002387	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1081093002388	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1081093002389	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
1081093002390	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1081093002391	Substrate binding site; other site
1081093002392	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1081093002393	phosphomannomutase CpsG; Provisional; Region: PRK15414
1081093002394	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1081093002395	active site
1081093002396	substrate binding site [chemical binding]; other site
1081093002397	metal binding site [ion binding]; metal-binding site
1081093002398	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
1081093002399	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
1081093002400	colanic acid exporter; Provisional; Region: PRK10459
1081093002401	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1081093002402	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; cl09156
1081093002403	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1081093002404	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
1081093002405	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1081093002406	putative ADP-binding pocket [chemical binding]; other site
1081093002407	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
1081093002408	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1081093002409	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1081093002410	active site
1081093002411	tetramer interface; other site
1081093002412	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1081093002413	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1081093002414	NAD binding site [chemical binding]; other site
1081093002415	substrate binding site [chemical binding]; other site
1081093002416	homodimer interface [polypeptide binding]; other site
1081093002417	active site
1081093002418	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
1081093002419	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1081093002420	NADP binding site [chemical binding]; other site
1081093002421	active site
1081093002422	putative substrate binding site [chemical binding]; other site
1081093002423	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
1081093002424	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1081093002425	substrate binding site; other site
1081093002426	tetramer interface; other site
1081093002427	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1081093002428	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
1081093002429	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1081093002430	catalytic loop [active]
1081093002431	iron binding site [ion binding]; other site
1081093002432	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1081093002433	FAD binding pocket [chemical binding]; other site
1081093002434	FAD binding motif [chemical binding]; other site
1081093002435	phosphate binding motif [ion binding]; other site
1081093002436	beta-alpha-beta structure motif; other site
1081093002437	NAD binding pocket [chemical binding]; other site
1081093002438	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1081093002439	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1081093002440	substrate binding site; other site
1081093002441	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1081093002442	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
1081093002443	NAD binding site [chemical binding]; other site
1081093002444	homotetramer interface [polypeptide binding]; other site
1081093002445	homodimer interface [polypeptide binding]; other site
1081093002446	substrate binding site [chemical binding]; other site
1081093002447	active site
1081093002448	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1081093002449	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1081093002450	inhibitor-cofactor binding pocket; inhibition site
1081093002451	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093002452	catalytic residue [active]
1081093002453	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1081093002454	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1081093002455	active site
1081093002456	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
1081093002457	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1081093002458	NAD binding site [chemical binding]; other site
1081093002459	homotetramer interface [polypeptide binding]; other site
1081093002460	homodimer interface [polypeptide binding]; other site
1081093002461	active site
1081093002462	substrate binding site [chemical binding]; other site
1081093002463	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1081093002464	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
1081093002465	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1081093002466	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1081093002467	active site
1081093002468	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1081093002469	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1081093002470	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1081093002471	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1081093002472	active site
1081093002473	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1081093002474	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1081093002475	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1081093002476	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1081093002477	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1081093002478	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
1081093002479	active site
1081093002480	substrate binding site [chemical binding]; other site
1081093002481	metal binding site [ion binding]; metal-binding site
1081093002482	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1081093002483	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1081093002484	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1081093002485	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1081093002486	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1081093002487	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1081093002488	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1081093002489	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1081093002490	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1081093002491	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1081093002492	chain length determinant protein WzzB; Provisional; Region: PRK15471
1081093002493	Chain length determinant protein; Region: Wzz; cl15801
1081093002494	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1081093002495	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1081093002496	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1081093002497	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1081093002498	metal binding site [ion binding]; metal-binding site
1081093002499	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1081093002500	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1081093002501	substrate binding site [chemical binding]; other site
1081093002502	glutamase interaction surface [polypeptide binding]; other site
1081093002503	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1081093002504	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1081093002505	catalytic residues [active]
1081093002506	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1081093002507	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1081093002508	putative active site [active]
1081093002509	oxyanion strand; other site
1081093002510	catalytic triad [active]
1081093002511	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1081093002512	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093002513	active site
1081093002514	motif I; other site
1081093002515	motif II; other site
1081093002516	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1081093002517	putative active site pocket [active]
1081093002518	4-fold oligomerization interface [polypeptide binding]; other site
1081093002519	metal binding residues [ion binding]; metal-binding site
1081093002520	3-fold/trimer interface [polypeptide binding]; other site
1081093002521	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1081093002522	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093002523	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093002524	homodimer interface [polypeptide binding]; other site
1081093002525	catalytic residue [active]
1081093002526	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1081093002527	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1081093002528	NAD binding site [chemical binding]; other site
1081093002529	dimerization interface [polypeptide binding]; other site
1081093002530	product binding site; other site
1081093002531	substrate binding site [chemical binding]; other site
1081093002532	zinc binding site [ion binding]; other site
1081093002533	catalytic residues [active]
1081093002534	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1081093002535	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1081093002536	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1081093002537	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1081093002538	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1081093002539	putative NAD(P) binding site [chemical binding]; other site
1081093002540	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093002541	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1081093002542	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093002543	dimerization interface [polypeptide binding]; other site
1081093002544	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1081093002545	exonuclease I; Provisional; Region: sbcB; PRK11779
1081093002546	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1081093002547	active site
1081093002548	catalytic site [active]
1081093002549	substrate binding site [chemical binding]; other site
1081093002550	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1081093002551	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
1081093002552	thiosulfate reductase PhsA; Provisional; Region: PRK15488
1081093002553	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1081093002554	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
1081093002555	putative [Fe4-S4] binding site [ion binding]; other site
1081093002556	putative molybdopterin cofactor binding site [chemical binding]; other site
1081093002557	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1081093002558	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
1081093002559	putative molybdopterin cofactor binding site; other site
1081093002560	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1081093002561	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
1081093002562	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1081093002563	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1081093002564	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1081093002565	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1081093002566	DNA gyrase inhibitor; Provisional; Region: PRK10016
1081093002567	Predicted membrane protein [Function unknown]; Region: COG1289
1081093002568	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1081093002569	hypothetical protein; Provisional; Region: PRK05423
1081093002570	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
1081093002571	propionate kinase; Reviewed; Region: PRK12397
1081093002572	propionate/acetate kinase; Provisional; Region: PRK12379
1081093002573	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
1081093002574	G3 box; other site
1081093002575	Switch II region; other site
1081093002576	GTP/Mg2+ binding site [chemical binding]; other site
1081093002577	G4 box; other site
1081093002578	G5 box; other site
1081093002579	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1081093002580	putative hexamer interface [polypeptide binding]; other site
1081093002581	putative hexagonal pore; other site
1081093002582	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1081093002583	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1081093002584	putative hexamer interface [polypeptide binding]; other site
1081093002585	putative hexagonal pore; other site
1081093002586	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1081093002587	putative hexamer interface [polypeptide binding]; other site
1081093002588	putative hexagonal pore; other site
1081093002589	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1081093002590	SLBB domain; Region: SLBB; pfam10531
1081093002591	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1081093002592	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
1081093002593	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1081093002594	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1081093002595	putative active site [active]
1081093002596	metal binding site [ion binding]; metal-binding site
1081093002597	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1081093002598	putative catalytic cysteine [active]
1081093002599	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1081093002600	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
1081093002601	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1081093002602	Hexamer/Pentamer interface [polypeptide binding]; other site
1081093002603	central pore; other site
1081093002604	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
1081093002605	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1081093002606	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1081093002607	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1081093002608	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1081093002609	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
1081093002610	putative hexamer interface [polypeptide binding]; other site
1081093002611	putative hexagonal pore; other site
1081093002612	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1081093002613	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1081093002614	Hexamer interface [polypeptide binding]; other site
1081093002615	Putative hexagonal pore residue; other site
1081093002616	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
1081093002617	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
1081093002618	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
1081093002619	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
1081093002620	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
1081093002621	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
1081093002622	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
1081093002623	alpha-beta subunit interface [polypeptide binding]; other site
1081093002624	alpha-gamma subunit interface [polypeptide binding]; other site
1081093002625	active site
1081093002626	substrate and K+ binding site; other site
1081093002627	K+ binding site [ion binding]; other site
1081093002628	cobalamin binding site [chemical binding]; other site
1081093002629	propanediol utilization protein PduB; Provisional; Region: PRK15415
1081093002630	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
1081093002631	putative hexamer interface [polypeptide binding]; other site
1081093002632	putative hexagonal pore; other site
1081093002633	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
1081093002634	putative hexamer interface [polypeptide binding]; other site
1081093002635	putative hexagonal pore; other site
1081093002636	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1081093002637	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1081093002638	Hexamer interface [polypeptide binding]; other site
1081093002639	Putative hexagonal pore residue; other site
1081093002640	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1081093002641	amphipathic channel; other site
1081093002642	Asn-Pro-Ala signature motifs; other site
1081093002643	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1081093002644	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1081093002645	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1081093002646	catalytic triad [active]
1081093002647	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1081093002648	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
1081093002649	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1081093002650	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1081093002651	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1081093002652	active site
1081093002653	putative homodimer interface [polypeptide binding]; other site
1081093002654	SAM binding site [chemical binding]; other site
1081093002655	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1081093002656	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093002657	S-adenosylmethionine binding site [chemical binding]; other site
1081093002658	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1081093002659	active site
1081093002660	SAM binding site [chemical binding]; other site
1081093002661	homodimer interface [polypeptide binding]; other site
1081093002662	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1081093002663	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1081093002664	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1081093002665	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1081093002666	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1081093002667	homodimer interface [polypeptide binding]; other site
1081093002668	active site
1081093002669	SAM binding site [chemical binding]; other site
1081093002670	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1081093002671	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1081093002672	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
1081093002673	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
1081093002674	active site
1081093002675	C-terminal domain interface [polypeptide binding]; other site
1081093002676	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1081093002677	active site
1081093002678	N-terminal domain interface [polypeptide binding]; other site
1081093002679	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1081093002680	active site
1081093002681	SAM binding site [chemical binding]; other site
1081093002682	homodimer interface [polypeptide binding]; other site
1081093002683	cobalt transport protein CbiM; Validated; Region: PRK08319
1081093002684	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1081093002685	cobalt transport protein CbiN; Provisional; Region: PRK02898
1081093002686	cobalt transport protein CbiQ; Provisional; Region: PRK15485
1081093002687	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
1081093002688	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1081093002689	Walker A/P-loop; other site
1081093002690	ATP binding site [chemical binding]; other site
1081093002691	Q-loop/lid; other site
1081093002692	ABC transporter signature motif; other site
1081093002693	Walker B; other site
1081093002694	D-loop; other site
1081093002695	H-loop/switch region; other site
1081093002696	cobyric acid synthase; Provisional; Region: PRK00784
1081093002697	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1081093002698	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1081093002699	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1081093002700	catalytic triad [active]
1081093002701	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1081093002702	homotrimer interface [polypeptide binding]; other site
1081093002703	Walker A motif; other site
1081093002704	GTP binding site [chemical binding]; other site
1081093002705	Walker B motif; other site
1081093002706	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1081093002707	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1081093002708	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1081093002709	putative dimer interface [polypeptide binding]; other site
1081093002710	active site pocket [active]
1081093002711	putative cataytic base [active]
1081093002712	L,D-transpeptidase; Provisional; Region: PRK10190
1081093002713	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1081093002714	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1081093002715	AMP nucleosidase; Provisional; Region: PRK08292
1081093002716	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1081093002717	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1081093002718	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
1081093002719	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1081093002720	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1081093002721	Sel1 repeat; Region: Sel1; pfam08238
1081093002722	Sel1-like repeats; Region: SEL1; smart00671
1081093002723	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
1081093002724	Integrase; Region: Integrase_1; pfam12835
1081093002725	putative protease; Region: PHA00666
1081093002726	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1081093002727	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
1081093002728	active site
1081093002729	NTP binding site [chemical binding]; other site
1081093002730	metal binding triad [ion binding]; metal-binding site
1081093002731	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1081093002732	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1081093002733	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1081093002734	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093002735	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
1081093002736	MobA/MobL family; Region: MobA_MobL; pfam03389
1081093002737	Conjugal transfer protein TraD; Region: TraD; pfam06412
1081093002738	PilS N terminal; Region: PilS; pfam08805
1081093002739	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
1081093002740	Phage Tail Collar Domain; Region: Collar; pfam07484
1081093002741	TIR domain; Region: TIR_2; pfam13676
1081093002742	integrase; Provisional; Region: PRK09692
1081093002743	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1081093002744	active site
1081093002745	Int/Topo IB signature motif; other site
1081093002746	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1081093002747	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1081093002748	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1081093002749	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1081093002750	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1081093002751	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1081093002752	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1081093002753	DNA-binding interface [nucleotide binding]; DNA binding site
1081093002754	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1081093002755	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1081093002756	putative ligand binding site [chemical binding]; other site
1081093002757	NAD binding site [chemical binding]; other site
1081093002758	dimerization interface [polypeptide binding]; other site
1081093002759	catalytic site [active]
1081093002760	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1081093002761	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1081093002762	curli assembly protein CsgF; Provisional; Region: PRK10050
1081093002763	curli assembly protein CsgE; Provisional; Region: PRK10386
1081093002764	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1081093002765	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093002766	DNA binding residues [nucleotide binding]
1081093002767	dimerization interface [polypeptide binding]; other site
1081093002768	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1081093002769	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1081093002770	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1081093002771	major curlin subunit; Provisional; Region: csgA; PRK10051
1081093002772	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1081093002773	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
1081093002774	Fimbrial protein; Region: Fimbrial; cl01416
1081093002775	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1081093002776	putative ADP-ribose binding site [chemical binding]; other site
1081093002777	putative active site [active]
1081093002778	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1081093002779	PLD-like domain; Region: PLDc_2; pfam13091
1081093002780	putative active site [active]
1081093002781	catalytic site [active]
1081093002782	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1081093002783	PLD-like domain; Region: PLDc_2; pfam13091
1081093002784	putative active site [active]
1081093002785	catalytic site [active]
1081093002786	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
1081093002787	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1081093002788	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1081093002789	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1081093002790	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1081093002791	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1081093002792	Ligand binding site; other site
1081093002793	DXD motif; other site
1081093002794	lipoprotein; Provisional; Region: PRK10175
1081093002795	drug efflux system protein MdtG; Provisional; Region: PRK09874
1081093002796	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093002797	putative substrate translocation pore; other site
1081093002798	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1081093002799	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1081093002800	putative acyl-acceptor binding pocket; other site
1081093002801	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1081093002802	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1081093002803	active site residue [active]
1081093002804	hypothetical protein; Provisional; Region: PRK03757
1081093002805	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1081093002806	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
1081093002807	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1081093002808	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1081093002809	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1081093002810	DNA damage-inducible protein I; Provisional; Region: PRK10597
1081093002811	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1081093002812	active site
1081093002813	substrate binding pocket [chemical binding]; other site
1081093002814	dimer interface [polypeptide binding]; other site
1081093002815	lipoprotein; Provisional; Region: PRK10598
1081093002816	glutaredoxin 2; Provisional; Region: PRK10387
1081093002817	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1081093002818	C-terminal domain interface [polypeptide binding]; other site
1081093002819	GSH binding site (G-site) [chemical binding]; other site
1081093002820	catalytic residues [active]
1081093002821	putative dimer interface [polypeptide binding]; other site
1081093002822	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1081093002823	N-terminal domain interface [polypeptide binding]; other site
1081093002824	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1081093002825	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093002826	putative substrate translocation pore; other site
1081093002827	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1081093002828	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1081093002829	hypothetical protein; Provisional; Region: PRK11239
1081093002830	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1081093002831	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1081093002832	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1081093002833	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1081093002834	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1081093002835	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1081093002836	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1081093002837	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1081093002838	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
1081093002839	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1081093002840	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1081093002841	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1081093002842	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1081093002843	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1081093002844	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1081093002845	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1081093002846	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
1081093002847	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1081093002848	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1081093002849	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1081093002850	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1081093002851	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1081093002852	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1081093002853	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1081093002854	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1081093002855	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1081093002856	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1081093002857	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1081093002858	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1081093002859	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1081093002860	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1081093002861	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1081093002862	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1081093002863	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1081093002864	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1081093002865	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1081093002866	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1081093002867	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1081093002868	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1081093002869	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1081093002870	homodimer interface [polypeptide binding]; other site
1081093002871	oligonucleotide binding site [chemical binding]; other site
1081093002872	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1081093002873	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1081093002874	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1081093002875	RNA binding surface [nucleotide binding]; other site
1081093002876	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1081093002877	active site
1081093002878	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1081093002879	Maf-like protein; Region: Maf; pfam02545
1081093002880	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1081093002881	active site
1081093002882	dimer interface [polypeptide binding]; other site
1081093002883	hypothetical protein; Provisional; Region: PRK11193
1081093002884	putative phosphate acyltransferase; Provisional; Region: PRK05331
1081093002885	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1081093002886	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1081093002887	dimer interface [polypeptide binding]; other site
1081093002888	active site
1081093002889	CoA binding pocket [chemical binding]; other site
1081093002890	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1081093002891	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1081093002892	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1081093002893	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1081093002894	NAD(P) binding site [chemical binding]; other site
1081093002895	homotetramer interface [polypeptide binding]; other site
1081093002896	homodimer interface [polypeptide binding]; other site
1081093002897	active site
1081093002898	acyl carrier protein; Provisional; Region: acpP; PRK00982
1081093002899	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1081093002900	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1081093002901	dimer interface [polypeptide binding]; other site
1081093002902	active site
1081093002903	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1081093002904	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1081093002905	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093002906	catalytic residue [active]
1081093002907	conserved hypothetical protein, YceG family; Region: TIGR00247
1081093002908	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1081093002909	dimerization interface [polypeptide binding]; other site
1081093002910	thymidylate kinase; Validated; Region: tmk; PRK00698
1081093002911	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1081093002912	TMP-binding site; other site
1081093002913	ATP-binding site [chemical binding]; other site
1081093002914	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1081093002915	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1081093002916	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1081093002917	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1081093002918	active site
1081093002919	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1081093002920	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1081093002921	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1081093002922	active site turn [active]
1081093002923	phosphorylation site [posttranslational modification]
1081093002924	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1081093002925	nucleotide binding site/active site [active]
1081093002926	HIT family signature motif; other site
1081093002927	catalytic residue [active]
1081093002928	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1081093002929	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1081093002930	putative dimer interface [polypeptide binding]; other site
1081093002931	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1081093002932	thiamine kinase; Region: ycfN_thiK; TIGR02721
1081093002933	thiamine kinase; Provisional; Region: thiK; PRK10271
1081093002934	substrate binding site [chemical binding]; other site
1081093002935	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1081093002936	beta-hexosaminidase; Provisional; Region: PRK05337
1081093002937	hypothetical protein; Provisional; Region: PRK04940
1081093002938	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1081093002939	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093002940	hypothetical protein; Provisional; Region: PRK11280
1081093002941	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1081093002942	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093002943	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093002944	L,D-transpeptidase; Provisional; Region: PRK10190
1081093002945	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1081093002946	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1081093002947	transcription-repair coupling factor; Provisional; Region: PRK10689
1081093002948	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1081093002949	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1081093002950	ATP binding site [chemical binding]; other site
1081093002951	putative Mg++ binding site [ion binding]; other site
1081093002952	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093002953	nucleotide binding region [chemical binding]; other site
1081093002954	ATP-binding site [chemical binding]; other site
1081093002955	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1081093002956	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1081093002957	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1081093002958	FtsX-like permease family; Region: FtsX; pfam02687
1081093002959	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1081093002960	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1081093002961	Walker A/P-loop; other site
1081093002962	ATP binding site [chemical binding]; other site
1081093002963	Q-loop/lid; other site
1081093002964	ABC transporter signature motif; other site
1081093002965	Walker B; other site
1081093002966	D-loop; other site
1081093002967	H-loop/switch region; other site
1081093002968	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1081093002969	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1081093002970	FtsX-like permease family; Region: FtsX; pfam02687
1081093002971	fructokinase; Reviewed; Region: PRK09557
1081093002972	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1081093002973	nucleotide binding site [chemical binding]; other site
1081093002974	NAD-dependent deacetylase; Provisional; Region: PRK00481
1081093002975	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1081093002976	NAD+ binding site [chemical binding]; other site
1081093002977	substrate binding site [chemical binding]; other site
1081093002978	Zn binding site [ion binding]; other site
1081093002979	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1081093002980	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1081093002981	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1081093002982	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093002983	dimer interface [polypeptide binding]; other site
1081093002984	conserved gate region; other site
1081093002985	putative PBP binding loops; other site
1081093002986	ABC-ATPase subunit interface; other site
1081093002987	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1081093002988	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093002989	dimer interface [polypeptide binding]; other site
1081093002990	conserved gate region; other site
1081093002991	putative PBP binding loops; other site
1081093002992	ABC-ATPase subunit interface; other site
1081093002993	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1081093002994	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093002995	Walker A/P-loop; other site
1081093002996	ATP binding site [chemical binding]; other site
1081093002997	Q-loop/lid; other site
1081093002998	ABC transporter signature motif; other site
1081093002999	Walker B; other site
1081093003000	D-loop; other site
1081093003001	H-loop/switch region; other site
1081093003002	TOBE domain; Region: TOBE_2; pfam08402
1081093003003	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1081093003004	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1081093003005	metal binding site [ion binding]; metal-binding site
1081093003006	dimer interface [polypeptide binding]; other site
1081093003007	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1081093003008	Cupin domain; Region: Cupin_2; cl17218
1081093003009	sensor protein PhoQ; Provisional; Region: PRK10815
1081093003010	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1081093003011	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1081093003012	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093003013	ATP binding site [chemical binding]; other site
1081093003014	Mg2+ binding site [ion binding]; other site
1081093003015	G-X-G motif; other site
1081093003016	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1081093003017	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093003018	active site
1081093003019	phosphorylation site [posttranslational modification]
1081093003020	intermolecular recognition site; other site
1081093003021	dimerization interface [polypeptide binding]; other site
1081093003022	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093003023	DNA binding site [nucleotide binding]
1081093003024	adenylosuccinate lyase; Provisional; Region: PRK09285
1081093003025	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1081093003026	tetramer interface [polypeptide binding]; other site
1081093003027	active site
1081093003028	putative lysogenization regulator; Reviewed; Region: PRK00218
1081093003029	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1081093003030	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1081093003031	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1081093003032	nudix motif; other site
1081093003033	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
1081093003034	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1081093003035	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1081093003036	pseudouridine synthase; Region: TIGR00093
1081093003037	probable active site [active]
1081093003038	isocitrate dehydrogenase; Validated; Region: PRK07362
1081093003039	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1081093003040	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
1081093003041	DinI-like family; Region: DinI; pfam06183
1081093003042	Ricin-type beta-trefoil; Region: RICIN; smart00458
1081093003043	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1081093003044	putative sugar binding sites [chemical binding]; other site
1081093003045	Q-X-W motif; other site
1081093003046	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1081093003047	lysozyme inhibitor; Provisional; Region: PRK13791
1081093003048	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1081093003049	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1081093003050	putative dimer interface [polypeptide binding]; other site
1081093003051	TRL-like protein family; Region: TRL; pfam13146
1081093003052	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
1081093003053	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1081093003054	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1081093003055	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093003056	dimer interface [polypeptide binding]; other site
1081093003057	conserved gate region; other site
1081093003058	ABC-ATPase subunit interface; other site
1081093003059	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1081093003060	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093003061	dimer interface [polypeptide binding]; other site
1081093003062	conserved gate region; other site
1081093003063	putative PBP binding loops; other site
1081093003064	ABC-ATPase subunit interface; other site
1081093003065	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093003066	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
1081093003067	Walker A/P-loop; other site
1081093003068	ATP binding site [chemical binding]; other site
1081093003069	Q-loop/lid; other site
1081093003070	ABC transporter signature motif; other site
1081093003071	Walker B; other site
1081093003072	D-loop; other site
1081093003073	H-loop/switch region; other site
1081093003074	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093003075	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1081093003076	Walker A/P-loop; other site
1081093003077	ATP binding site [chemical binding]; other site
1081093003078	Q-loop/lid; other site
1081093003079	ABC transporter signature motif; other site
1081093003080	Walker B; other site
1081093003081	D-loop; other site
1081093003082	H-loop/switch region; other site
1081093003083	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1081093003084	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1081093003085	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
1081093003086	dimerization interface [polypeptide binding]; other site
1081093003087	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1081093003088	aminoglycoside resistance protein; Provisional; Region: PRK13746
1081093003089	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1081093003090	active site
1081093003091	NTP binding site [chemical binding]; other site
1081093003092	metal binding triad [ion binding]; metal-binding site
1081093003093	antibiotic binding site [chemical binding]; other site
1081093003094	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1081093003095	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093003096	DNA binding residues [nucleotide binding]
1081093003097	transcriptional regulator MirA; Provisional; Region: PRK15043
1081093003098	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
1081093003099	DNA binding residues [nucleotide binding]
1081093003100	dimer interface [polypeptide binding]; other site
1081093003101	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1081093003102	chorismate mutase; Provisional; Region: PRK08055
1081093003103	leucine export protein LeuE; Provisional; Region: PRK10958
1081093003104	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1081093003105	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1081093003106	hypothetical protein; Provisional; Region: PRK10457
1081093003107	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1081093003108	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1081093003109	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1081093003110	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1081093003111	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1081093003112	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003113	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1081093003114	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093003115	Predicted membrane protein [Function unknown]; Region: COG2707
1081093003116	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1081093003117	putative deacylase active site [active]
1081093003118	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093003119	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093003120	active site
1081093003121	catalytic tetrad [active]
1081093003122	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1081093003123	active site
1081093003124	phosphate binding residues; other site
1081093003125	catalytic residues [active]
1081093003126	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1081093003127	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1081093003128	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1081093003129	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1081093003130	SelR domain; Region: SelR; pfam01641
1081093003131	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1081093003132	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003133	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003134	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1081093003135	intersubunit interface [polypeptide binding]; other site
1081093003136	active site
1081093003137	zinc binding site [ion binding]; other site
1081093003138	Na+ binding site [ion binding]; other site
1081093003139	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1081093003140	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093003141	substrate binding site [chemical binding]; other site
1081093003142	ATP binding site [chemical binding]; other site
1081093003143	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093003144	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093003145	active site
1081093003146	catalytic tetrad [active]
1081093003147	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093003148	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1081093003149	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093003150	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1081093003151	Isochorismatase family; Region: Isochorismatase; pfam00857
1081093003152	catalytic triad [active]
1081093003153	metal binding site [ion binding]; metal-binding site
1081093003154	conserved cis-peptide bond; other site
1081093003155	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1081093003156	active site
1081093003157	homodimer interface [polypeptide binding]; other site
1081093003158	protease 4; Provisional; Region: PRK10949
1081093003159	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1081093003160	tandem repeat interface [polypeptide binding]; other site
1081093003161	oligomer interface [polypeptide binding]; other site
1081093003162	active site residues [active]
1081093003163	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1081093003164	tandem repeat interface [polypeptide binding]; other site
1081093003165	oligomer interface [polypeptide binding]; other site
1081093003166	active site residues [active]
1081093003167	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1081093003168	putative FMN binding site [chemical binding]; other site
1081093003169	selenophosphate synthetase; Provisional; Region: PRK00943
1081093003170	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1081093003171	dimerization interface [polypeptide binding]; other site
1081093003172	putative ATP binding site [chemical binding]; other site
1081093003173	DNA topoisomerase III; Provisional; Region: PRK07726
1081093003174	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1081093003175	active site
1081093003176	putative interdomain interaction site [polypeptide binding]; other site
1081093003177	putative metal-binding site [ion binding]; other site
1081093003178	putative nucleotide binding site [chemical binding]; other site
1081093003179	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1081093003180	domain I; other site
1081093003181	DNA binding groove [nucleotide binding]
1081093003182	phosphate binding site [ion binding]; other site
1081093003183	domain II; other site
1081093003184	domain III; other site
1081093003185	nucleotide binding site [chemical binding]; other site
1081093003186	catalytic site [active]
1081093003187	domain IV; other site
1081093003188	glutamate dehydrogenase; Provisional; Region: PRK09414
1081093003189	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1081093003190	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1081093003191	NAD(P) binding site [chemical binding]; other site
1081093003192	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1081093003193	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1081093003194	active site
1081093003195	8-oxo-dGMP binding site [chemical binding]; other site
1081093003196	nudix motif; other site
1081093003197	metal binding site [ion binding]; metal-binding site
1081093003198	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1081093003199	putative catalytic site [active]
1081093003200	putative phosphate binding site [ion binding]; other site
1081093003201	active site
1081093003202	metal binding site A [ion binding]; metal-binding site
1081093003203	DNA binding site [nucleotide binding]
1081093003204	putative AP binding site [nucleotide binding]; other site
1081093003205	putative metal binding site B [ion binding]; other site
1081093003206	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1081093003207	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1081093003208	inhibitor-cofactor binding pocket; inhibition site
1081093003209	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093003210	catalytic residue [active]
1081093003211	Arginine N-succinyltransferase beta subunit; Region: AstA; cl11440
1081093003212	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1081093003213	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1081093003214	NAD(P) binding site [chemical binding]; other site
1081093003215	catalytic residues [active]
1081093003216	succinylarginine dihydrolase; Provisional; Region: PRK13281
1081093003217	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1081093003218	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1081093003219	putative active site [active]
1081093003220	Zn binding site [ion binding]; other site
1081093003221	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1081093003222	dimer interface [polypeptide binding]; other site
1081093003223	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1081093003224	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1081093003225	GIY-YIG motif/motif A; other site
1081093003226	active site
1081093003227	catalytic site [active]
1081093003228	putative DNA binding site [nucleotide binding]; other site
1081093003229	metal binding site [ion binding]; metal-binding site
1081093003230	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1081093003231	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1081093003232	homodimer interface [polypeptide binding]; other site
1081093003233	NAD binding pocket [chemical binding]; other site
1081093003234	ATP binding pocket [chemical binding]; other site
1081093003235	Mg binding site [ion binding]; other site
1081093003236	active-site loop [active]
1081093003237	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1081093003238	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1081093003239	active site
1081093003240	P-loop; other site
1081093003241	phosphorylation site [posttranslational modification]
1081093003242	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1081093003243	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1081093003244	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1081093003245	methionine cluster; other site
1081093003246	active site
1081093003247	phosphorylation site [posttranslational modification]
1081093003248	metal binding site [ion binding]; metal-binding site
1081093003249	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1081093003250	Cupin domain; Region: Cupin_2; pfam07883
1081093003251	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093003252	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1081093003253	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1081093003254	NAD binding site [chemical binding]; other site
1081093003255	sugar binding site [chemical binding]; other site
1081093003256	divalent metal binding site [ion binding]; other site
1081093003257	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1081093003258	dimer interface [polypeptide binding]; other site
1081093003259	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1081093003260	putative active site [active]
1081093003261	YdjC motif; other site
1081093003262	Mg binding site [ion binding]; other site
1081093003263	putative homodimer interface [polypeptide binding]; other site
1081093003264	hydroperoxidase II; Provisional; Region: katE; PRK11249
1081093003265	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1081093003266	tetramer interface [polypeptide binding]; other site
1081093003267	heme binding pocket [chemical binding]; other site
1081093003268	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1081093003269	domain interactions; other site
1081093003270	cell division modulator; Provisional; Region: PRK10113
1081093003271	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1081093003272	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1081093003273	inner membrane protein; Provisional; Region: PRK11648
1081093003274	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1081093003275	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1081093003276	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093003277	motif II; other site
1081093003278	YniB-like protein; Region: YniB; pfam14002
1081093003279	Phosphotransferase enzyme family; Region: APH; pfam01636
1081093003280	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1081093003281	active site
1081093003282	ATP binding site [chemical binding]; other site
1081093003283	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1081093003284	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1081093003285	6-phosphofructokinase 2; Provisional; Region: PRK10294
1081093003286	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1081093003287	putative substrate binding site [chemical binding]; other site
1081093003288	putative ATP binding site [chemical binding]; other site
1081093003289	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1081093003290	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
1081093003291	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
1081093003292	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1081093003293	active site
1081093003294	substrate binding site [chemical binding]; other site
1081093003295	Mg2+ binding site [ion binding]; other site
1081093003296	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1081093003297	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1081093003298	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1081093003299	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1081093003300	active site
1081093003301	dimer interface [polypeptide binding]; other site
1081093003302	motif 1; other site
1081093003303	motif 2; other site
1081093003304	motif 3; other site
1081093003305	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1081093003306	anticodon binding site; other site
1081093003307	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1081093003308	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1081093003309	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1081093003310	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1081093003311	23S rRNA binding site [nucleotide binding]; other site
1081093003312	L21 binding site [polypeptide binding]; other site
1081093003313	L13 binding site [polypeptide binding]; other site
1081093003314	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1081093003315	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1081093003316	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1081093003317	dimer interface [polypeptide binding]; other site
1081093003318	motif 1; other site
1081093003319	active site
1081093003320	motif 2; other site
1081093003321	motif 3; other site
1081093003322	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1081093003323	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1081093003324	putative tRNA-binding site [nucleotide binding]; other site
1081093003325	B3/4 domain; Region: B3_4; pfam03483
1081093003326	tRNA synthetase B5 domain; Region: B5; smart00874
1081093003327	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1081093003328	dimer interface [polypeptide binding]; other site
1081093003329	motif 1; other site
1081093003330	motif 3; other site
1081093003331	motif 2; other site
1081093003332	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1081093003333	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1081093003334	IHF dimer interface [polypeptide binding]; other site
1081093003335	IHF - DNA interface [nucleotide binding]; other site
1081093003336	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1081093003337	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1081093003338	ABC-ATPase subunit  interface; other site
1081093003339	dimer interface [polypeptide binding]; other site
1081093003340	putative PBP binding regions; other site
1081093003341	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1081093003342	catalytic residues [active]
1081093003343	dimer interface [polypeptide binding]; other site
1081093003344	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
1081093003345	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1081093003346	Walker A/P-loop; other site
1081093003347	ATP binding site [chemical binding]; other site
1081093003348	Q-loop/lid; other site
1081093003349	ABC transporter signature motif; other site
1081093003350	Walker B; other site
1081093003351	D-loop; other site
1081093003352	H-loop/switch region; other site
1081093003353	NlpC/P60 family; Region: NLPC_P60; pfam00877
1081093003354	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
1081093003355	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1081093003356	hypothetical protein; Validated; Region: PRK00029
1081093003357	hypothetical protein; Provisional; Region: PRK10183
1081093003358	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1081093003359	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1081093003360	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1081093003361	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
1081093003362	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
1081093003363	acyl-activating enzyme (AAE) consensus motif; other site
1081093003364	putative AMP binding site [chemical binding]; other site
1081093003365	putative active site [active]
1081093003366	putative CoA binding site [chemical binding]; other site
1081093003367	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1081093003368	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
1081093003369	Electron transfer flavoprotein domain; Region: ETF; smart00893
1081093003370	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1081093003371	Cupin domain; Region: Cupin_2; pfam07883
1081093003372	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1081093003373	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093003374	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
1081093003375	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1081093003376	active site
1081093003377	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1081093003378	Coenzyme A transferase; Region: CoA_trans; smart00882
1081093003379	Coenzyme A transferase; Region: CoA_trans; cl17247
1081093003380	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1081093003381	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1081093003382	active site
1081093003383	catalytic residue [active]
1081093003384	dimer interface [polypeptide binding]; other site
1081093003385	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
1081093003386	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1081093003387	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1081093003388	shikimate binding site; other site
1081093003389	NAD(P) binding site [chemical binding]; other site
1081093003390	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003391	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1081093003392	putative substrate translocation pore; other site
1081093003393	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003394	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1081093003395	putative substrate translocation pore; other site
1081093003396	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
1081093003397	putative inner membrane protein; Provisional; Region: PRK10983
1081093003398	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1081093003399	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1081093003400	FAD binding domain; Region: FAD_binding_4; pfam01565
1081093003401	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1081093003402	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1081093003403	CoenzymeA binding site [chemical binding]; other site
1081093003404	subunit interaction site [polypeptide binding]; other site
1081093003405	PHB binding site; other site
1081093003406	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1081093003407	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1081093003408	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1081093003409	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1081093003410	putative ABC transporter; Region: ycf24; CHL00085
1081093003411	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1081093003412	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1081093003413	Walker A/P-loop; other site
1081093003414	ATP binding site [chemical binding]; other site
1081093003415	Q-loop/lid; other site
1081093003416	ABC transporter signature motif; other site
1081093003417	Walker B; other site
1081093003418	D-loop; other site
1081093003419	H-loop/switch region; other site
1081093003420	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1081093003421	FeS assembly protein SufD; Region: sufD; TIGR01981
1081093003422	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1081093003423	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1081093003424	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1081093003425	catalytic residue [active]
1081093003426	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1081093003427	murein lipoprotein; Provisional; Region: PRK15396
1081093003428	murein lipoprotein; Provisional; Region: PRK15396
1081093003429	pyruvate kinase; Provisional; Region: PRK09206
1081093003430	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1081093003431	domain interfaces; other site
1081093003432	active site
1081093003433	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1081093003434	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093003435	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1081093003436	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093003437	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1081093003438	substrate binding site [chemical binding]; other site
1081093003439	dimer interface [polypeptide binding]; other site
1081093003440	ATP binding site [chemical binding]; other site
1081093003441	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1081093003442	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1081093003443	putative [Fe4-S4] binding site [ion binding]; other site
1081093003444	putative molybdopterin cofactor binding site [chemical binding]; other site
1081093003445	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1081093003446	putative molybdopterin cofactor binding site; other site
1081093003447	tetrathionate reductase subunit C; Provisional; Region: PRK14992
1081093003448	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1081093003449	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1081093003450	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093003451	active site
1081093003452	phosphorylation site [posttranslational modification]
1081093003453	intermolecular recognition site; other site
1081093003454	dimerization interface [polypeptide binding]; other site
1081093003455	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093003456	DNA binding residues [nucleotide binding]
1081093003457	dimerization interface [polypeptide binding]; other site
1081093003458	hypothetical protein; Provisional; Region: PRK10292
1081093003459	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1081093003460	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1081093003461	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1081093003462	transcriptional regulator MirA; Provisional; Region: PRK15043
1081093003463	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1081093003464	DNA binding residues [nucleotide binding]
1081093003465	two component system sensor kinase SsrB; Provisional; Region: PRK15369
1081093003466	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093003467	active site
1081093003468	phosphorylation site [posttranslational modification]
1081093003469	intermolecular recognition site; other site
1081093003470	dimerization interface [polypeptide binding]; other site
1081093003471	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093003472	DNA binding residues [nucleotide binding]
1081093003473	dimerization interface [polypeptide binding]; other site
1081093003474	two component system sensor kinase SsrA; Provisional; Region: PRK15347
1081093003475	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093003476	dimerization interface [polypeptide binding]; other site
1081093003477	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093003478	dimer interface [polypeptide binding]; other site
1081093003479	phosphorylation site [posttranslational modification]
1081093003480	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093003481	ATP binding site [chemical binding]; other site
1081093003482	Mg2+ binding site [ion binding]; other site
1081093003483	G-X-G motif; other site
1081093003484	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093003485	active site
1081093003486	phosphorylation site [posttranslational modification]
1081093003487	intermolecular recognition site; other site
1081093003488	dimerization interface [polypeptide binding]; other site
1081093003489	outer membrane secretin SsaC; Provisional; Region: PRK15346
1081093003490	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1081093003491	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1081093003492	type III secretion system protein SsaD; Provisional; Region: PRK15367
1081093003493	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
1081093003494	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
1081093003495	EspA-like secreted protein; Region: EspA; cl04069
1081093003496	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
1081093003497	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
1081093003498	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
1081093003499	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
1081093003500	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
1081093003501	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1081093003502	TPR motif; other site
1081093003503	binding surface
1081093003504	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
1081093003505	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
1081093003506	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
1081093003507	type III secretion system protein SsaH; Provisional; Region: PRK15356
1081093003508	type III secretion system protein SsaI; Provisional; Region: PRK15355
1081093003509	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
1081093003510	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
1081093003511	type III secretion system protein SsaK; Provisional; Region: PRK15354
1081093003512	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
1081093003513	type III secretion system protein SsaL; Provisional; Region: PRK15345
1081093003514	HrpJ-like domain; Region: HrpJ; pfam07201
1081093003515	TyeA; Region: TyeA; cl07611
1081093003516	type III secretion system protein SsaM; Provisional; Region: PRK15353
1081093003517	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
1081093003518	FHIPEP family; Region: FHIPEP; pfam00771
1081093003519	type III secretion system ATPase SsaN; Validated; Region: PRK07594
1081093003520	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1081093003521	Walker A motif; other site
1081093003522	ATP binding site [chemical binding]; other site
1081093003523	Walker B motif; other site
1081093003524	type III secretion system protein SsaO; Provisional; Region: PRK15352
1081093003525	type III secretion system protein SsaP; Provisional; Region: PRK15351
1081093003526	type III secretion system protein SsaQ; Validated; Region: PRK08035
1081093003527	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1081093003528	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
1081093003529	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
1081093003530	type III secretion system protein SsaT; Provisional; Region: PRK15349
1081093003531	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
1081093003532	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1081093003533	multidrug efflux protein; Reviewed; Region: PRK01766
1081093003534	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1081093003535	cation binding site [ion binding]; other site
1081093003536	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1081093003537	Lumazine binding domain; Region: Lum_binding; pfam00677
1081093003538	Lumazine binding domain; Region: Lum_binding; pfam00677
1081093003539	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1081093003540	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093003541	S-adenosylmethionine binding site [chemical binding]; other site
1081093003542	putative transporter; Provisional; Region: PRK11043
1081093003543	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003544	putative substrate translocation pore; other site
1081093003545	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1081093003546	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093003547	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093003548	dimerization interface [polypeptide binding]; other site
1081093003549	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1081093003550	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093003551	DNA binding site [nucleotide binding]
1081093003552	domain linker motif; other site
1081093003553	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1081093003554	dimerization interface [polypeptide binding]; other site
1081093003555	ligand binding site [chemical binding]; other site
1081093003556	superoxide dismutase; Provisional; Region: PRK10543
1081093003557	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1081093003558	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1081093003559	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1081093003560	NlpC/P60 family; Region: NLPC_P60; pfam00877
1081093003561	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1081093003562	putative GSH binding site [chemical binding]; other site
1081093003563	catalytic residues [active]
1081093003564	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1081093003565	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1081093003566	dimer interface [polypeptide binding]; other site
1081093003567	catalytic site [active]
1081093003568	putative active site [active]
1081093003569	putative substrate binding site [chemical binding]; other site
1081093003570	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1081093003571	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1081093003572	dimer interface [polypeptide binding]; other site
1081093003573	active site
1081093003574	metal binding site [ion binding]; metal-binding site
1081093003575	glutathione binding site [chemical binding]; other site
1081093003576	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1081093003577	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1081093003578	FMN binding site [chemical binding]; other site
1081093003579	active site
1081093003580	substrate binding site [chemical binding]; other site
1081093003581	catalytic residue [active]
1081093003582	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1081093003583	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093003584	Protein of unknown function (DUF1289); Region: DUF1289; cl01304
1081093003585	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093003586	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093003587	active site
1081093003588	catalytic tetrad [active]
1081093003589	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1081093003590	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1081093003591	E-class dimer interface [polypeptide binding]; other site
1081093003592	P-class dimer interface [polypeptide binding]; other site
1081093003593	active site
1081093003594	Cu2+ binding site [ion binding]; other site
1081093003595	Zn2+ binding site [ion binding]; other site
1081093003596	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1081093003597	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1081093003598	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1081093003599	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1081093003600	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093003601	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1081093003602	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1081093003603	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1081093003604	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1081093003605	lysozyme inhibitor; Provisional; Region: PRK11372
1081093003606	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1081093003607	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1081093003608	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1081093003609	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1081093003610	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1081093003611	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1081093003612	active site
1081093003613	HIGH motif; other site
1081093003614	dimer interface [polypeptide binding]; other site
1081093003615	KMSKS motif; other site
1081093003616	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1081093003617	RNA binding surface [nucleotide binding]; other site
1081093003618	glutathionine S-transferase; Provisional; Region: PRK10542
1081093003619	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1081093003620	C-terminal domain interface [polypeptide binding]; other site
1081093003621	GSH binding site (G-site) [chemical binding]; other site
1081093003622	dimer interface [polypeptide binding]; other site
1081093003623	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1081093003624	dimer interface [polypeptide binding]; other site
1081093003625	N-terminal domain interface [polypeptide binding]; other site
1081093003626	substrate binding pocket (H-site) [chemical binding]; other site
1081093003627	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1081093003628	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003629	putative substrate translocation pore; other site
1081093003630	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003631	endonuclease III; Provisional; Region: PRK10702
1081093003632	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1081093003633	minor groove reading motif; other site
1081093003634	helix-hairpin-helix signature motif; other site
1081093003635	substrate binding pocket [chemical binding]; other site
1081093003636	active site
1081093003637	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1081093003638	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1081093003639	electron transport complex protein RnfG; Validated; Region: PRK01908
1081093003640	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1081093003641	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1081093003642	SLBB domain; Region: SLBB; pfam10531
1081093003643	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1081093003644	electron transport complex protein RnfB; Provisional; Region: PRK05113
1081093003645	Putative Fe-S cluster; Region: FeS; cl17515
1081093003646	4Fe-4S binding domain; Region: Fer4; pfam00037
1081093003647	electron transport complex protein RsxA; Provisional; Region: PRK05151
1081093003648	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1081093003649	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1081093003650	putative oxidoreductase; Provisional; Region: PRK11579
1081093003651	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1081093003652	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1081093003653	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1081093003654	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1081093003655	active site
1081093003656	purine riboside binding site [chemical binding]; other site
1081093003657	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cl00164
1081093003658	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1081093003659	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1081093003660	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1081093003661	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1081093003662	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1081093003663	fumarate hydratase; Provisional; Region: PRK15389
1081093003664	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1081093003665	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1081093003666	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1081093003667	Class II fumarases; Region: Fumarase_classII; cd01362
1081093003668	active site
1081093003669	tetramer interface [polypeptide binding]; other site
1081093003670	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1081093003671	sensor protein RstB; Provisional; Region: PRK10604
1081093003672	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093003673	dimerization interface [polypeptide binding]; other site
1081093003674	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093003675	dimer interface [polypeptide binding]; other site
1081093003676	phosphorylation site [posttranslational modification]
1081093003677	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093003678	ATP binding site [chemical binding]; other site
1081093003679	Mg2+ binding site [ion binding]; other site
1081093003680	G-X-G motif; other site
1081093003681	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1081093003682	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1081093003683	active site
1081093003684	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1081093003685	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1081093003686	trimer interface [polypeptide binding]; other site
1081093003687	eyelet of channel; other site
1081093003688	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1081093003689	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093003690	active site
1081093003691	phosphorylation site [posttranslational modification]
1081093003692	intermolecular recognition site; other site
1081093003693	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093003694	DNA binding site [nucleotide binding]
1081093003695	GlpM protein; Region: GlpM; pfam06942
1081093003696	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1081093003697	Spore germination protein; Region: Spore_permease; cl17796
1081093003698	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093003699	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093003700	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093003701	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1081093003702	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1081093003703	ligand binding site [chemical binding]; other site
1081093003704	homodimer interface [polypeptide binding]; other site
1081093003705	NAD(P) binding site [chemical binding]; other site
1081093003706	trimer interface B [polypeptide binding]; other site
1081093003707	trimer interface A [polypeptide binding]; other site
1081093003708	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1081093003709	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1081093003710	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1081093003711	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1081093003712	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1081093003713	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1081093003714	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1081093003715	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1081093003716	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003717	putative substrate translocation pore; other site
1081093003718	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1081093003719	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093003720	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1081093003721	dimerization interface [polypeptide binding]; other site
1081093003722	substrate binding pocket [chemical binding]; other site
1081093003723	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1081093003724	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1081093003725	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1081093003726	nucleotide binding site [chemical binding]; other site
1081093003727	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1081093003728	AAA domain; Region: AAA_26; pfam13500
1081093003729	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1081093003730	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1081093003731	Cl- selectivity filter; other site
1081093003732	Cl- binding residues [ion binding]; other site
1081093003733	pore gating glutamate residue; other site
1081093003734	dimer interface [polypeptide binding]; other site
1081093003735	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1081093003736	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1081093003737	Walker A/P-loop; other site
1081093003738	ATP binding site [chemical binding]; other site
1081093003739	Q-loop/lid; other site
1081093003740	ABC transporter signature motif; other site
1081093003741	Walker B; other site
1081093003742	D-loop; other site
1081093003743	H-loop/switch region; other site
1081093003744	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
1081093003745	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093003746	dimer interface [polypeptide binding]; other site
1081093003747	conserved gate region; other site
1081093003748	ABC-ATPase subunit interface; other site
1081093003749	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1081093003750	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093003751	dimer interface [polypeptide binding]; other site
1081093003752	conserved gate region; other site
1081093003753	putative PBP binding loops; other site
1081093003754	ABC-ATPase subunit interface; other site
1081093003755	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1081093003756	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1081093003757	4Fe-4S binding domain; Region: Fer4; pfam00037
1081093003758	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1081093003759	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1081093003760	putative [Fe4-S4] binding site [ion binding]; other site
1081093003761	putative molybdopterin cofactor binding site [chemical binding]; other site
1081093003762	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1081093003763	putative molybdopterin cofactor binding site; other site
1081093003764	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1081093003765	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
1081093003766	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1081093003767	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093003768	Coenzyme A binding pocket [chemical binding]; other site
1081093003769	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1081093003770	hypothetical protein; Provisional; Region: PRK13659
1081093003771	hypothetical protein; Provisional; Region: PRK02237
1081093003772	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1081093003773	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1081093003774	putative active site pocket [active]
1081093003775	putative metal binding site [ion binding]; other site
1081093003776	putative oxidoreductase; Provisional; Region: PRK10083
1081093003777	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1081093003778	putative NAD(P) binding site [chemical binding]; other site
1081093003779	catalytic Zn binding site [ion binding]; other site
1081093003780	structural Zn binding site [ion binding]; other site
1081093003781	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003782	metabolite-proton symporter; Region: 2A0106; TIGR00883
1081093003783	putative substrate translocation pore; other site
1081093003784	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1081093003785	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1081093003786	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1081093003787	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
1081093003788	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1081093003789	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093003790	DNA-binding site [nucleotide binding]; DNA binding site
1081093003791	FCD domain; Region: FCD; pfam07729
1081093003792	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1081093003793	short chain dehydrogenase; Provisional; Region: PRK06924
1081093003794	putative NAD(P) binding site [chemical binding]; other site
1081093003795	homotetramer interface [polypeptide binding]; other site
1081093003796	homodimer interface [polypeptide binding]; other site
1081093003797	active site
1081093003798	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1081093003799	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1081093003800	active site
1081093003801	Zn binding site [ion binding]; other site
1081093003802	General stress protein [General function prediction only]; Region: GsiB; COG3729
1081093003803	hypothetical protein; Validated; Region: PRK03657
1081093003804	hypothetical protein; Provisional; Region: PRK10053
1081093003805	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1081093003806	EamA-like transporter family; Region: EamA; pfam00892
1081093003807	MarB protein; Region: MarB; pfam13999
1081093003808	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1081093003809	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093003810	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093003811	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1081093003812	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1081093003813	inner membrane protein; Provisional; Region: PRK10995
1081093003814	putative arabinose transporter; Provisional; Region: PRK03545
1081093003815	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003816	putative substrate translocation pore; other site
1081093003817	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093003818	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093003819	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1081093003820	putative dimerization interface [polypeptide binding]; other site
1081093003821	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1081093003822	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1081093003823	NAD(P) binding site [chemical binding]; other site
1081093003824	catalytic residues [active]
1081093003825	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1081093003826	glutaminase; Provisional; Region: PRK00971
1081093003827	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1081093003828	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1081093003829	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1081093003830	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1081093003831	trimer interface [polypeptide binding]; other site
1081093003832	eyelet of channel; other site
1081093003833	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1081093003834	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1081093003835	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
1081093003836	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1081093003837	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1081093003838	Rubredoxin [Energy production and conversion]; Region: COG1773
1081093003839	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1081093003840	iron binding site [ion binding]; other site
1081093003841	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1081093003842	HupF/HypC family; Region: HupF_HypC; cl00394
1081093003843	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1081093003844	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1081093003845	putative substrate-binding site; other site
1081093003846	nickel binding site [ion binding]; other site
1081093003847	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
1081093003848	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1081093003849	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1081093003850	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
1081093003851	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1081093003852	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1081093003853	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
1081093003854	active site
1081093003855	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1081093003856	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093003857	DNA-binding site [nucleotide binding]; DNA binding site
1081093003858	FCD domain; Region: FCD; pfam07729
1081093003859	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1081093003860	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1081093003861	putative NAD(P) binding site [chemical binding]; other site
1081093003862	catalytic Zn binding site [ion binding]; other site
1081093003863	structural Zn binding site [ion binding]; other site
1081093003864	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003865	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1081093003866	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093003867	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093003868	homodimer interface [polypeptide binding]; other site
1081093003869	catalytic residue [active]
1081093003870	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1081093003871	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1081093003872	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1081093003873	active site
1081093003874	catalytic site [active]
1081093003875	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
1081093003876	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1081093003877	active site
1081093003878	catalytic site [active]
1081093003879	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
1081093003880	acid-resistance protein; Provisional; Region: hdeB; PRK11566
1081093003881	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1081093003882	biofilm-dependent modulation protein; Provisional; Region: PRK11436
1081093003883	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
1081093003884	malate dehydrogenase; Provisional; Region: PRK13529
1081093003885	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1081093003886	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1081093003887	NAD(P) binding site [chemical binding]; other site
1081093003888	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1081093003889	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1081093003890	NAD binding site [chemical binding]; other site
1081093003891	substrate binding site [chemical binding]; other site
1081093003892	catalytic Zn binding site [ion binding]; other site
1081093003893	tetramer interface [polypeptide binding]; other site
1081093003894	structural Zn binding site [ion binding]; other site
1081093003895	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1081093003896	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1081093003897	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1081093003898	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1081093003899	aromatic amino acid exporter; Provisional; Region: PRK11689
1081093003900	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1081093003901	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1081093003902	trimer interface [polypeptide binding]; other site
1081093003903	eyelet of channel; other site
1081093003904	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1081093003905	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1081093003906	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093003907	putative substrate translocation pore; other site
1081093003908	TetR family transcriptional regulator; Provisional; Region: PRK14996
1081093003909	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093003910	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
1081093003911	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1081093003912	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
1081093003913	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1081093003914	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
1081093003915	L-asparagine permease; Provisional; Region: PRK15049
1081093003916	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1081093003917	DNA-binding site [nucleotide binding]; DNA binding site
1081093003918	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1081093003919	FCD domain; Region: FCD; pfam07729
1081093003920	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1081093003921	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1081093003922	NAD(P) binding site [chemical binding]; other site
1081093003923	substrate binding site [chemical binding]; other site
1081093003924	dimer interface [polypeptide binding]; other site
1081093003925	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1081093003926	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1081093003927	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1081093003928	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1081093003929	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
1081093003930	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
1081093003931	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1081093003932	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
1081093003933	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1081093003934	tetrameric interface [polypeptide binding]; other site
1081093003935	NAD binding site [chemical binding]; other site
1081093003936	catalytic residues [active]
1081093003937	substrate binding site [chemical binding]; other site
1081093003938	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1081093003939	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093003940	DNA-binding site [nucleotide binding]; DNA binding site
1081093003941	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093003942	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093003943	homodimer interface [polypeptide binding]; other site
1081093003944	catalytic residue [active]
1081093003945	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
1081093003946	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1081093003947	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1081093003948	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1081093003949	Peptidase family U32; Region: Peptidase_U32; pfam01136
1081093003950	Collagenase; Region: DUF3656; pfam12392
1081093003951	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1081093003952	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093003953	non-specific DNA binding site [nucleotide binding]; other site
1081093003954	salt bridge; other site
1081093003955	sequence-specific DNA binding site [nucleotide binding]; other site
1081093003956	Cupin domain; Region: Cupin_2; pfam07883
1081093003957	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1081093003958	tellurite resistance protein TehB; Provisional; Region: PRK11207
1081093003959	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093003960	S-adenosylmethionine binding site [chemical binding]; other site
1081093003961	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1081093003962	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1081093003963	gating phenylalanine in ion channel; other site
1081093003964	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1081093003965	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1081093003966	putative trimer interface [polypeptide binding]; other site
1081093003967	putative CoA binding site [chemical binding]; other site
1081093003968	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1081093003969	putative trimer interface [polypeptide binding]; other site
1081093003970	putative CoA binding site [chemical binding]; other site
1081093003971	ribosomal-protein-L7/L12-serine acetyltransferase; Provisional; Region: PRK10151
1081093003972	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1081093003973	Coenzyme A binding pocket [chemical binding]; other site
1081093003974	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1081093003975	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1081093003976	oligomer interface [polypeptide binding]; other site
1081093003977	active site
1081093003978	metal binding site [ion binding]; metal-binding site
1081093003979	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1081093003980	active site
1081093003981	P-loop; other site
1081093003982	phosphorylation site [posttranslational modification]
1081093003983	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1081093003984	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
1081093003985	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
1081093003986	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1081093003987	active site
1081093003988	phosphorylation site [posttranslational modification]
1081093003989	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1081093003990	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1081093003991	substrate binding site [chemical binding]; other site
1081093003992	hexamer interface [polypeptide binding]; other site
1081093003993	metal binding site [ion binding]; metal-binding site
1081093003994	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093003995	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1081093003996	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093003997	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093003998	Coenzyme A binding pocket [chemical binding]; other site
1081093003999	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1081093004000	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1081093004001	metal binding site [ion binding]; metal-binding site
1081093004002	substrate binding pocket [chemical binding]; other site
1081093004003	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1081093004004	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1081093004005	NADP binding site [chemical binding]; other site
1081093004006	homodimer interface [polypeptide binding]; other site
1081093004007	active site
1081093004008	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093004009	D-galactonate transporter; Region: 2A0114; TIGR00893
1081093004010	putative substrate translocation pore; other site
1081093004011	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1081093004012	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1081093004013	putative NAD(P) binding site [chemical binding]; other site
1081093004014	catalytic Zn binding site [ion binding]; other site
1081093004015	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1081093004016	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093004017	DNA-binding site [nucleotide binding]; DNA binding site
1081093004018	FCD domain; Region: FCD; pfam07729
1081093004019	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1081093004020	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1081093004021	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1081093004022	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1081093004023	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1081093004024	substrate binding pocket [chemical binding]; other site
1081093004025	catalytic triad [active]
1081093004026	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1081093004027	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1081093004028	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1081093004029	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093004030	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093004031	dimerization interface [polypeptide binding]; other site
1081093004032	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1081093004033	dimer interface [polypeptide binding]; other site
1081093004034	ligand binding site [chemical binding]; other site
1081093004035	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1081093004036	HAMP domain; Region: HAMP; pfam00672
1081093004037	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1081093004038	dimer interface [polypeptide binding]; other site
1081093004039	putative CheW interface [polypeptide binding]; other site
1081093004040	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1081093004041	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1081093004042	substrate binding site [chemical binding]; other site
1081093004043	catalytic Zn binding site [ion binding]; other site
1081093004044	NAD binding site [chemical binding]; other site
1081093004045	structural Zn binding site [ion binding]; other site
1081093004046	dimer interface [polypeptide binding]; other site
1081093004047	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1081093004048	putative metal binding site [ion binding]; other site
1081093004049	putative homodimer interface [polypeptide binding]; other site
1081093004050	putative homotetramer interface [polypeptide binding]; other site
1081093004051	putative homodimer-homodimer interface [polypeptide binding]; other site
1081093004052	putative allosteric switch controlling residues; other site
1081093004053	Sif protein; Region: Sif; cl11505
1081093004054	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1081093004055	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
1081093004056	active site
1081093004057	catalytic triad [active]
1081093004058	oxyanion hole [active]
1081093004059	Predicted membrane protein [Function unknown]; Region: COG3326
1081093004060	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093004061	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1081093004062	substrate binding pocket [chemical binding]; other site
1081093004063	membrane-bound complex binding site; other site
1081093004064	hinge residues; other site
1081093004065	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093004066	dimer interface [polypeptide binding]; other site
1081093004067	ABC-ATPase subunit interface; other site
1081093004068	putative PBP binding loops; other site
1081093004069	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1081093004070	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093004071	Walker A/P-loop; other site
1081093004072	ATP binding site [chemical binding]; other site
1081093004073	Q-loop/lid; other site
1081093004074	ABC transporter signature motif; other site
1081093004075	Walker B; other site
1081093004076	D-loop; other site
1081093004077	H-loop/switch region; other site
1081093004078	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1081093004079	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093004080	dimer interface [polypeptide binding]; other site
1081093004081	conserved gate region; other site
1081093004082	putative PBP binding loops; other site
1081093004083	ABC-ATPase subunit interface; other site
1081093004084	Predicted membrane protein [Function unknown]; Region: COG5305
1081093004085	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093004086	S-adenosylmethionine binding site [chemical binding]; other site
1081093004087	cytochrome b561; Provisional; Region: PRK11513
1081093004088	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1081093004089	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1081093004090	putative active site [active]
1081093004091	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1081093004092	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1081093004093	ATP binding site [chemical binding]; other site
1081093004094	putative Mg++ binding site [ion binding]; other site
1081093004095	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093004096	nucleotide binding region [chemical binding]; other site
1081093004097	ATP-binding site [chemical binding]; other site
1081093004098	Helicase associated domain (HA2); Region: HA2; pfam04408
1081093004099	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1081093004100	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1081093004101	azoreductase; Reviewed; Region: PRK00170
1081093004102	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1081093004103	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1081093004104	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1081093004105	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1081093004106	hypothetical protein; Provisional; Region: PRK10695
1081093004107	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1081093004108	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1081093004109	putative ligand binding site [chemical binding]; other site
1081093004110	putative NAD binding site [chemical binding]; other site
1081093004111	catalytic site [active]
1081093004112	heat-inducible protein; Provisional; Region: PRK10449
1081093004113	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1081093004114	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1081093004115	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1081093004116	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1081093004117	dimer interface [polypeptide binding]; other site
1081093004118	PYR/PP interface [polypeptide binding]; other site
1081093004119	TPP binding site [chemical binding]; other site
1081093004120	substrate binding site [chemical binding]; other site
1081093004121	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1081093004122	Domain of unknown function; Region: EKR; smart00890
1081093004123	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1081093004124	4Fe-4S binding domain; Region: Fer4; pfam00037
1081093004125	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1081093004126	TPP-binding site [chemical binding]; other site
1081093004127	dimer interface [polypeptide binding]; other site
1081093004128	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1081093004129	Ligand Binding Site [chemical binding]; other site
1081093004130	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1081093004131	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1081093004132	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1081093004133	Ligand Binding Site [chemical binding]; other site
1081093004134	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1081093004135	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1081093004136	ATP binding site [chemical binding]; other site
1081093004137	Mg++ binding site [ion binding]; other site
1081093004138	motif III; other site
1081093004139	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093004140	nucleotide binding region [chemical binding]; other site
1081093004141	ATP-binding site [chemical binding]; other site
1081093004142	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1081093004143	putative RNA binding site [nucleotide binding]; other site
1081093004144	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1081093004145	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1081093004146	Cl binding site [ion binding]; other site
1081093004147	oligomer interface [polypeptide binding]; other site
1081093004148	HAMP domain; Region: HAMP; pfam00672
1081093004149	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1081093004150	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1081093004151	dimer interface [polypeptide binding]; other site
1081093004152	putative CheW interface [polypeptide binding]; other site
1081093004153	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1081093004154	Smr domain; Region: Smr; pfam01713
1081093004155	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1081093004156	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1081093004157	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1081093004158	DNA binding site [nucleotide binding]
1081093004159	active site
1081093004160	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1081093004161	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1081093004162	ligand binding site [chemical binding]; other site
1081093004163	flexible hinge region; other site
1081093004164	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1081093004165	putative switch regulator; other site
1081093004166	non-specific DNA interactions [nucleotide binding]; other site
1081093004167	DNA binding site [nucleotide binding]
1081093004168	sequence specific DNA binding site [nucleotide binding]; other site
1081093004169	putative cAMP binding site [chemical binding]; other site
1081093004170	universal stress protein UspE; Provisional; Region: PRK11175
1081093004171	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1081093004172	Ligand Binding Site [chemical binding]; other site
1081093004173	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1081093004174	Ligand Binding Site [chemical binding]; other site
1081093004175	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1081093004176	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1081093004177	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1081093004178	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093004179	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093004180	active site
1081093004181	catalytic tetrad [active]
1081093004182	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093004183	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093004184	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1081093004185	putative effector binding pocket; other site
1081093004186	putative dimerization interface [polypeptide binding]; other site
1081093004187	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1081093004188	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1081093004189	peptide binding site [polypeptide binding]; other site
1081093004190	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1081093004191	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1081093004192	putative active site [active]
1081093004193	Zn binding site [ion binding]; other site
1081093004194	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1081093004195	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1081093004196	active site
1081093004197	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1081093004198	dimer interface [polypeptide binding]; other site
1081093004199	catalytic triad [active]
1081093004200	peroxidatic and resolving cysteines [active]
1081093004201	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1081093004202	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1081093004203	putative aromatic amino acid binding site; other site
1081093004204	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093004205	Walker A motif; other site
1081093004206	ATP binding site [chemical binding]; other site
1081093004207	Walker B motif; other site
1081093004208	arginine finger; other site
1081093004209	hypothetical protein; Provisional; Region: PRK05415
1081093004210	TIGR01620 family protein; Region: hyp_HI0043
1081093004211	Predicted ATPase [General function prediction only]; Region: COG3106
1081093004212	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1081093004213	active site residue [active]
1081093004214	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1081093004215	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1081093004216	phage shock protein C; Region: phageshock_pspC; TIGR02978
1081093004217	phage shock protein B; Provisional; Region: pspB; PRK09458
1081093004218	phage shock protein PspA; Provisional; Region: PRK10698
1081093004219	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1081093004220	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093004221	Walker A motif; other site
1081093004222	ATP binding site [chemical binding]; other site
1081093004223	Walker B motif; other site
1081093004224	arginine finger; other site
1081093004225	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1081093004226	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1081093004227	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1081093004228	peptide binding site [polypeptide binding]; other site
1081093004229	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1081093004230	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093004231	dimer interface [polypeptide binding]; other site
1081093004232	conserved gate region; other site
1081093004233	putative PBP binding loops; other site
1081093004234	ABC-ATPase subunit interface; other site
1081093004235	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1081093004236	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1081093004237	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093004238	dimer interface [polypeptide binding]; other site
1081093004239	conserved gate region; other site
1081093004240	putative PBP binding loops; other site
1081093004241	ABC-ATPase subunit interface; other site
1081093004242	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1081093004243	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093004244	Walker A/P-loop; other site
1081093004245	ATP binding site [chemical binding]; other site
1081093004246	Q-loop/lid; other site
1081093004247	ABC transporter signature motif; other site
1081093004248	Walker B; other site
1081093004249	D-loop; other site
1081093004250	H-loop/switch region; other site
1081093004251	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1081093004252	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1081093004253	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093004254	Walker A/P-loop; other site
1081093004255	ATP binding site [chemical binding]; other site
1081093004256	Q-loop/lid; other site
1081093004257	ABC transporter signature motif; other site
1081093004258	Walker B; other site
1081093004259	D-loop; other site
1081093004260	H-loop/switch region; other site
1081093004261	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1081093004262	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1081093004263	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1081093004264	NAD binding site [chemical binding]; other site
1081093004265	homotetramer interface [polypeptide binding]; other site
1081093004266	homodimer interface [polypeptide binding]; other site
1081093004267	substrate binding site [chemical binding]; other site
1081093004268	active site
1081093004269	exoribonuclease II; Provisional; Region: PRK05054
1081093004270	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1081093004271	RNB domain; Region: RNB; pfam00773
1081093004272	S1 RNA binding domain; Region: S1; pfam00575
1081093004273	RNase II stability modulator; Provisional; Region: PRK10060
1081093004274	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1081093004275	putative active site [active]
1081093004276	heme pocket [chemical binding]; other site
1081093004277	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093004278	metal binding site [ion binding]; metal-binding site
1081093004279	active site
1081093004280	I-site; other site
1081093004281	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093004282	hypothetical protein; Provisional; Region: PRK13658
1081093004283	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093004284	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1081093004285	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093004286	lipoprotein; Provisional; Region: PRK10540
1081093004287	translation initiation factor Sui1; Validated; Region: PRK06824
1081093004288	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1081093004289	putative rRNA binding site [nucleotide binding]; other site
1081093004290	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1081093004291	active site
1081093004292	dimer interface [polypeptide binding]; other site
1081093004293	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1081093004294	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1081093004295	binding surface
1081093004296	TPR motif; other site
1081093004297	Predicted membrane protein [Function unknown]; Region: COG3771
1081093004298	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1081093004299	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1081093004300	active site
1081093004301	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1081093004302	dimerization interface [polypeptide binding]; other site
1081093004303	active site
1081093004304	aconitate hydratase; Validated; Region: PRK09277
1081093004305	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1081093004306	substrate binding site [chemical binding]; other site
1081093004307	ligand binding site [chemical binding]; other site
1081093004308	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1081093004309	substrate binding site [chemical binding]; other site
1081093004310	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1081093004311	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1081093004312	substrate binding site [chemical binding]; other site
1081093004313	putative dimerization interface [polypeptide binding]; other site
1081093004314	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
1081093004315	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1081093004316	active site
1081093004317	interdomain interaction site; other site
1081093004318	putative metal-binding site [ion binding]; other site
1081093004319	nucleotide binding site [chemical binding]; other site
1081093004320	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1081093004321	domain I; other site
1081093004322	DNA binding groove [nucleotide binding]
1081093004323	phosphate binding site [ion binding]; other site
1081093004324	domain II; other site
1081093004325	domain III; other site
1081093004326	nucleotide binding site [chemical binding]; other site
1081093004327	catalytic site [active]
1081093004328	domain IV; other site
1081093004329	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1081093004330	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1081093004331	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1081093004332	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
1081093004333	hypothetical protein; Provisional; Region: PRK11037
1081093004334	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1081093004335	putative inner membrane peptidase; Provisional; Region: PRK11778
1081093004336	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1081093004337	tandem repeat interface [polypeptide binding]; other site
1081093004338	oligomer interface [polypeptide binding]; other site
1081093004339	active site residues [active]
1081093004340	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1081093004341	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1081093004342	NADP binding site [chemical binding]; other site
1081093004343	homodimer interface [polypeptide binding]; other site
1081093004344	active site
1081093004345	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1081093004346	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
1081093004347	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1081093004348	homodimer interface [polypeptide binding]; other site
1081093004349	Walker A motif; other site
1081093004350	ATP binding site [chemical binding]; other site
1081093004351	hydroxycobalamin binding site [chemical binding]; other site
1081093004352	Walker B motif; other site
1081093004353	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1081093004354	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1081093004355	RNA binding surface [nucleotide binding]; other site
1081093004356	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1081093004357	probable active site [active]
1081093004358	hypothetical protein; Provisional; Region: PRK11630
1081093004359	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1081093004360	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1081093004361	active site
1081093004362	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1081093004363	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
1081093004364	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1081093004365	glutamine binding [chemical binding]; other site
1081093004366	catalytic triad [active]
1081093004367	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1081093004368	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1081093004369	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1081093004370	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1081093004371	active site
1081093004372	ribulose/triose binding site [chemical binding]; other site
1081093004373	phosphate binding site [ion binding]; other site
1081093004374	substrate (anthranilate) binding pocket [chemical binding]; other site
1081093004375	product (indole) binding pocket [chemical binding]; other site
1081093004376	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1081093004377	active site
1081093004378	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1081093004379	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1081093004380	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093004381	catalytic residue [active]
1081093004382	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1081093004383	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1081093004384	substrate binding site [chemical binding]; other site
1081093004385	active site
1081093004386	catalytic residues [active]
1081093004387	heterodimer interface [polypeptide binding]; other site
1081093004388	General stress protein [General function prediction only]; Region: GsiB; COG3729
1081093004389	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1081093004390	dimerization interface [polypeptide binding]; other site
1081093004391	metal binding site [ion binding]; metal-binding site
1081093004392	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1081093004393	dinuclear metal binding motif [ion binding]; other site
1081093004394	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1081093004395	dimanganese center [ion binding]; other site
1081093004396	outer membrane protein W; Provisional; Region: PRK10959
1081093004397	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1081093004398	hypothetical protein; Provisional; Region: PRK02868
1081093004399	intracellular septation protein A; Reviewed; Region: PRK00259
1081093004400	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1081093004401	transport protein TonB; Provisional; Region: PRK10819
1081093004402	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1081093004403	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1081093004404	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1081093004405	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1081093004406	putative active site [active]
1081093004407	catalytic site [active]
1081093004408	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1081093004409	putative active site [active]
1081093004410	catalytic site [active]
1081093004411	dsDNA-mimic protein; Reviewed; Region: PRK05094
1081093004412	Ion transport protein; Region: Ion_trans; pfam00520
1081093004413	Ion channel; Region: Ion_trans_2; pfam07885
1081093004414	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1081093004415	Double zinc ribbon; Region: DZR; pfam12773
1081093004416	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1081093004417	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093004418	Walker A/P-loop; other site
1081093004419	ATP binding site [chemical binding]; other site
1081093004420	Q-loop/lid; other site
1081093004421	ABC transporter signature motif; other site
1081093004422	Walker B; other site
1081093004423	D-loop; other site
1081093004424	H-loop/switch region; other site
1081093004425	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1081093004426	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1081093004427	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093004428	Walker A/P-loop; other site
1081093004429	ATP binding site [chemical binding]; other site
1081093004430	Q-loop/lid; other site
1081093004431	ABC transporter signature motif; other site
1081093004432	Walker B; other site
1081093004433	D-loop; other site
1081093004434	H-loop/switch region; other site
1081093004435	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1081093004436	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1081093004437	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1081093004438	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093004439	dimer interface [polypeptide binding]; other site
1081093004440	conserved gate region; other site
1081093004441	ABC-ATPase subunit interface; other site
1081093004442	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1081093004443	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093004444	dimer interface [polypeptide binding]; other site
1081093004445	conserved gate region; other site
1081093004446	putative PBP binding loops; other site
1081093004447	ABC-ATPase subunit interface; other site
1081093004448	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1081093004449	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1081093004450	peptide binding site [polypeptide binding]; other site
1081093004451	hypothetical protein; Provisional; Region: PRK11111
1081093004452	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1081093004453	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1081093004454	putative catalytic cysteine [active]
1081093004455	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1081093004456	putative active site [active]
1081093004457	metal binding site [ion binding]; metal-binding site
1081093004458	thymidine kinase; Provisional; Region: PRK04296
1081093004459	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1081093004460	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1081093004461	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1081093004462	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1081093004463	active site
1081093004464	tetramer interface; other site
1081093004465	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093004466	active site
1081093004467	response regulator of RpoS; Provisional; Region: PRK10693
1081093004468	phosphorylation site [posttranslational modification]
1081093004469	intermolecular recognition site; other site
1081093004470	dimerization interface [polypeptide binding]; other site
1081093004471	hypothetical protein; Provisional; Region: PRK01617
1081093004472	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1081093004473	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1081093004474	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1081093004475	putative active site [active]
1081093004476	putative substrate binding site [chemical binding]; other site
1081093004477	putative cosubstrate binding site; other site
1081093004478	catalytic site [active]
1081093004479	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1081093004480	Sel1-like repeats; Region: SEL1; smart00671
1081093004481	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1081093004482	Sel1-like repeats; Region: SEL1; smart00671
1081093004483	Sel1-like repeats; Region: SEL1; smart00671
1081093004484	Sel1-like repeats; Region: SEL1; smart00671
1081093004485	Sel1-like repeats; Region: SEL1; smart00671
1081093004486	Sel1-like repeats; Region: SEL1; smart00671
1081093004487	Sel1-like repeats; Region: SEL1; smart00671
1081093004488	Sel1-like repeats; Region: SEL1; smart00671
1081093004489	Sel1-like repeats; Region: SEL1; smart00671
1081093004490	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1081093004491	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1081093004492	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1081093004493	4Fe-4S binding domain; Region: Fer4; cl02805
1081093004494	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1081093004495	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1081093004496	[4Fe-4S] binding site [ion binding]; other site
1081093004497	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1081093004498	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1081093004499	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1081093004500	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1081093004501	molybdopterin cofactor binding site; other site
1081093004502	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1081093004503	transcriptional regulator NarL; Provisional; Region: PRK10651
1081093004504	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093004505	active site
1081093004506	phosphorylation site [posttranslational modification]
1081093004507	intermolecular recognition site; other site
1081093004508	dimerization interface [polypeptide binding]; other site
1081093004509	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093004510	DNA binding residues [nucleotide binding]
1081093004511	dimerization interface [polypeptide binding]; other site
1081093004512	putative invasin; Provisional; Region: PRK10177
1081093004513	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1081093004514	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1081093004515	cation transport regulator; Reviewed; Region: chaB; PRK09582
1081093004516	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
1081093004517	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1081093004518	hypothetical protein; Provisional; Region: PRK10941
1081093004519	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1081093004520	hypothetical protein; Provisional; Region: PRK10278
1081093004521	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1081093004522	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093004523	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1081093004524	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1081093004525	RF-1 domain; Region: RF-1; pfam00472
1081093004526	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1081093004527	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1081093004528	tRNA; other site
1081093004529	putative tRNA binding site [nucleotide binding]; other site
1081093004530	putative NADP binding site [chemical binding]; other site
1081093004531	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
1081093004532	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1081093004533	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1081093004534	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1081093004535	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1081093004536	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1081093004537	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1081093004538	active site
1081093004539	putative transporter; Provisional; Region: PRK11660
1081093004540	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1081093004541	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1081093004542	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1081093004543	hypothetical protein; Provisional; Region: PRK10692
1081093004544	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1081093004545	putative active site [active]
1081093004546	catalytic residue [active]
1081093004547	GTP-binding protein YchF; Reviewed; Region: PRK09601
1081093004548	YchF GTPase; Region: YchF; cd01900
1081093004549	G1 box; other site
1081093004550	GTP/Mg2+ binding site [chemical binding]; other site
1081093004551	Switch I region; other site
1081093004552	G2 box; other site
1081093004553	Switch II region; other site
1081093004554	G3 box; other site
1081093004555	G4 box; other site
1081093004556	G5 box; other site
1081093004557	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1081093004558	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1081093004559	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1081093004560	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1081093004561	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1081093004562	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1081093004563	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
1081093004564	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1081093004565	putative substrate-binding site; other site
1081093004566	nickel binding site [ion binding]; other site
1081093004567	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1081093004568	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1081093004569	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1081093004570	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
1081093004571	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1081093004572	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
1081093004573	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1081093004574	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1081093004575	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1081093004576	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1081093004577	NAD(P) binding site [chemical binding]; other site
1081093004578	trehalase; Provisional; Region: treA; PRK13271
1081093004579	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1081093004580	hypothetical protein; Provisional; Region: PRK10457
1081093004581	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1081093004582	Flagellar regulator YcgR; Region: YcgR; pfam07317
1081093004583	PilZ domain; Region: PilZ; pfam07238
1081093004584	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1081093004585	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1081093004586	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1081093004587	catalytic residue [active]
1081093004588	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1081093004589	dimer interface [polypeptide binding]; other site
1081093004590	catalytic triad [active]
1081093004591	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1081093004592	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1081093004593	TrkA-C domain; Region: TrkA_C; pfam02080
1081093004594	Transporter associated domain; Region: CorC_HlyC; smart01091
1081093004595	alanine racemase; Reviewed; Region: dadX; PRK03646
1081093004596	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1081093004597	active site
1081093004598	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1081093004599	substrate binding site [chemical binding]; other site
1081093004600	catalytic residues [active]
1081093004601	dimer interface [polypeptide binding]; other site
1081093004602	SpoVR family protein; Provisional; Region: PRK11767
1081093004603	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1081093004604	fatty acid metabolism regulator; Provisional; Region: PRK04984
1081093004605	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093004606	DNA-binding site [nucleotide binding]; DNA binding site
1081093004607	FadR C-terminal domain; Region: FadR_C; pfam07840
1081093004608	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1081093004609	transmembrane helices; other site
1081093004610	disulfide bond formation protein B; Provisional; Region: PRK01749
1081093004611	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1081093004612	GnsA/GnsB family; Region: GnsAB; pfam08178
1081093004613	hypothetical protein; Provisional; Region: PRK05170
1081093004614	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1081093004615	hypothetical protein; Provisional; Region: PRK10691
1081093004616	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1081093004617	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1081093004618	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1081093004619	cell division inhibitor MinD; Provisional; Region: PRK10818
1081093004620	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1081093004621	Switch I; other site
1081093004622	Switch II; other site
1081093004623	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1081093004624	ribonuclease D; Provisional; Region: PRK10829
1081093004625	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1081093004626	catalytic site [active]
1081093004627	putative active site [active]
1081093004628	putative substrate binding site [chemical binding]; other site
1081093004629	HRDC domain; Region: HRDC; cl02578
1081093004630	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1081093004631	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1081093004632	acyl-activating enzyme (AAE) consensus motif; other site
1081093004633	putative AMP binding site [chemical binding]; other site
1081093004634	putative active site [active]
1081093004635	putative CoA binding site [chemical binding]; other site
1081093004636	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
1081093004637	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1081093004638	Glycoprotease family; Region: Peptidase_M22; pfam00814
1081093004639	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1081093004640	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1081093004641	DEAD_2; Region: DEAD_2; pfam06733
1081093004642	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1081093004643	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1081093004644	homotrimer interaction site [polypeptide binding]; other site
1081093004645	putative active site [active]
1081093004646	hypothetical protein; Provisional; Region: PRK05114
1081093004647	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1081093004648	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1081093004649	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
1081093004650	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1081093004651	putative active site [active]
1081093004652	putative CoA binding site [chemical binding]; other site
1081093004653	nudix motif; other site
1081093004654	metal binding site [ion binding]; metal-binding site
1081093004655	L-serine deaminase; Provisional; Region: PRK15023
1081093004656	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1081093004657	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1081093004658	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1081093004659	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1081093004660	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1081093004661	Transporter associated domain; Region: CorC_HlyC; smart01091
1081093004662	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1081093004663	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1081093004664	active pocket/dimerization site; other site
1081093004665	active site
1081093004666	phosphorylation site [posttranslational modification]
1081093004667	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1081093004668	active site
1081093004669	phosphorylation site [posttranslational modification]
1081093004670	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1081093004671	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1081093004672	hypothetical protein; Provisional; Region: PRK11469
1081093004673	Domain of unknown function DUF; Region: DUF204; pfam02659
1081093004674	Domain of unknown function DUF; Region: DUF204; pfam02659
1081093004675	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1081093004676	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093004677	S-adenosylmethionine binding site [chemical binding]; other site
1081093004678	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1081093004679	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1081093004680	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1081093004681	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1081093004682	DNA-binding site [nucleotide binding]; DNA binding site
1081093004683	RNA-binding motif; other site
1081093004684	PhoPQ regulatory protein; Provisional; Region: PRK10299
1081093004685	YobH-like protein; Region: YobH; pfam13996
1081093004686	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1081093004687	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1081093004688	dimerization interface [polypeptide binding]; other site
1081093004689	putative Zn2+ binding site [ion binding]; other site
1081093004690	putative DNA binding site [nucleotide binding]; other site
1081093004691	Bacterial transcriptional regulator; Region: IclR; pfam01614
1081093004692	heat shock protein HtpX; Provisional; Region: PRK05457
1081093004693	carboxy-terminal protease; Provisional; Region: PRK11186
1081093004694	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1081093004695	protein binding site [polypeptide binding]; other site
1081093004696	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1081093004697	Catalytic dyad [active]
1081093004698	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1081093004699	ProP expression regulator; Provisional; Region: PRK04950
1081093004700	ProQ/FINO family; Region: ProQ; pfam04352
1081093004701	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1081093004702	GAF domain; Region: GAF_2; pfam13185
1081093004703	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1081093004704	Paraquat-inducible protein A; Region: PqiA; pfam04403
1081093004705	Paraquat-inducible protein A; Region: PqiA; pfam04403
1081093004706	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1081093004707	mce related protein; Region: MCE; pfam02470
1081093004708	mce related protein; Region: MCE; pfam02470
1081093004709	mce related protein; Region: MCE; pfam02470
1081093004710	mce related protein; Region: MCE; pfam02470
1081093004711	mce related protein; Region: MCE; pfam02470
1081093004712	mce related protein; Region: MCE; pfam02470
1081093004713	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1081093004714	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
1081093004715	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1081093004716	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1081093004717	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1081093004718	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1081093004719	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1081093004720	type III secretion protein SopE2; Provisional; Region: PRK15280
1081093004721	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
1081093004722	SopE GEF domain; Region: SopE_GEF; pfam07487
1081093004723	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
1081093004724	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1081093004725	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1081093004726	EamA-like transporter family; Region: EamA; pfam00892
1081093004727	EamA-like transporter family; Region: EamA; pfam00892
1081093004728	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1081093004729	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1081093004730	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1081093004731	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
1081093004732	ADP-ribose binding site [chemical binding]; other site
1081093004733	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1081093004734	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1081093004735	exonuclease VIII; Reviewed; Region: PRK09709
1081093004736	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1081093004737	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1081093004738	DNA binding site [nucleotide binding]
1081093004739	active site
1081093004740	Int/Topo IB signature motif; other site
1081093004741	type III secretion protein SopE; Provisional; Region: PRK15279
1081093004742	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
1081093004743	SopE GEF domain; Region: SopE_GEF; pfam07487
1081093004744	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1081093004745	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
1081093004746	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1081093004747	Phage Tail Collar Domain; Region: Collar; pfam07484
1081093004748	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
1081093004749	Fibronectin type III protein; Region: DUF3672; pfam12421
1081093004750	Phage-related protein, tail component [Function unknown]; Region: COG4723
1081093004751	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
1081093004752	MPN+ (JAMM) motif; other site
1081093004753	Zinc-binding site [ion binding]; other site
1081093004754	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1081093004755	NlpC/P60 family; Region: NLPC_P60; cl17555
1081093004756	Phage-related protein [Function unknown]; Region: gp18; COG4672
1081093004757	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cl00891
1081093004758	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1081093004759	active site
1081093004760	Cu2+ binding site [ion binding]; other site
1081093004761	Zn2+ binding site [ion binding]; other site
1081093004762	P-class dimer interface [polypeptide binding]; other site
1081093004763	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1081093004764	Phage-related protein [Function unknown]; Region: COG4718
1081093004765	Phage-related minor tail protein [Function unknown]; Region: COG5281
1081093004766	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
1081093004767	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
1081093004768	Minor tail protein T; Region: Phage_tail_T; cl05636
1081093004769	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
1081093004770	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
1081093004771	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
1081093004772	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
1081093004773	Uncharacterized conserved protein [Function unknown]; Region: COG5471
1081093004774	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1081093004775	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1081093004776	oligomer interface [polypeptide binding]; other site
1081093004777	active site residues [active]
1081093004778	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
1081093004779	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1081093004780	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1081093004781	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1081093004782	Domain of unknown function (DUF1859); Region: DUF1859; pfam08948
1081093004783	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1081093004784	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1081093004785	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1081093004786	catalytic residues [active]
1081093004787	phage holin, lambda family; Region: holin_lambda; TIGR01594
1081093004788	PipA protein; Region: PipA; pfam07108
1081093004789	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
1081093004790	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1081093004791	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1081093004792	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
1081093004793	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1081093004794	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1081093004795	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093004796	metal binding site [ion binding]; metal-binding site
1081093004797	active site
1081093004798	I-site; other site
1081093004799	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
1081093004800	Replication protein P; Region: Phage_lambda_P; pfam06992
1081093004801	Protein of unknown function (DUF1376); Region: DUF1376; cl01531
1081093004802	primosomal protein DnaI; Provisional; Region: PRK02854
1081093004803	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1081093004804	transcriptional repressor DicA; Reviewed; Region: PRK09706
1081093004805	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1081093004806	exonuclease VIII; Reviewed; Region: PRK09709
1081093004807	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
1081093004808	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
1081093004809	recombination and repair protein RecT; Reviewed; Region: recT; PRK09846
1081093004810	hypothetical protein; Provisional; Region: PRK09750
1081093004811	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1081093004812	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1081093004813	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1081093004814	dimer interface [polypeptide binding]; other site
1081093004815	active site
1081093004816	Int/Topo IB signature motif; other site
1081093004817	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1081093004818	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1081093004819	hypothetical protein; Provisional; Region: PRK10301
1081093004820	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1081093004821	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1081093004822	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
1081093004823	exodeoxyribonuclease X; Provisional; Region: PRK07983
1081093004824	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1081093004825	active site
1081093004826	catalytic site [active]
1081093004827	substrate binding site [chemical binding]; other site
1081093004828	protease 2; Provisional; Region: PRK10115
1081093004829	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1081093004830	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1081093004831	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1081093004832	putative metal binding site [ion binding]; other site
1081093004833	hypothetical protein; Provisional; Region: PRK13680
1081093004834	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
1081093004835	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1081093004836	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1081093004837	ATP-grasp domain; Region: ATP-grasp; pfam02222
1081093004838	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1081093004839	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1081093004840	active site
1081093004841	intersubunit interface [polypeptide binding]; other site
1081093004842	catalytic residue [active]
1081093004843	phosphogluconate dehydratase; Validated; Region: PRK09054
1081093004844	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1081093004845	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1081093004846	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1081093004847	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1081093004848	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1081093004849	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1081093004850	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1081093004851	putative active site [active]
1081093004852	pyruvate kinase; Provisional; Region: PRK05826
1081093004853	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1081093004854	domain interfaces; other site
1081093004855	active site
1081093004856	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1081093004857	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1081093004858	putative acyl-acceptor binding pocket; other site
1081093004859	putative peptidase; Provisional; Region: PRK11649
1081093004860	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1081093004861	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1081093004862	Peptidase family M23; Region: Peptidase_M23; pfam01551
1081093004863	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1081093004864	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1081093004865	metal binding site [ion binding]; metal-binding site
1081093004866	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1081093004867	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1081093004868	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1081093004869	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1081093004870	ABC-ATPase subunit  interface; other site
1081093004871	dimer interface [polypeptide binding]; other site
1081093004872	putative PBP binding regions; other site
1081093004873	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1081093004874	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093004875	Walker A motif; other site
1081093004876	ATP binding site [chemical binding]; other site
1081093004877	Walker B motif; other site
1081093004878	arginine finger; other site
1081093004879	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1081093004880	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1081093004881	RuvA N terminal domain; Region: RuvA_N; pfam01330
1081093004882	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1081093004883	hypothetical protein; Provisional; Region: PRK11470
1081093004884	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1081093004885	active site
1081093004886	putative DNA-binding cleft [nucleotide binding]; other site
1081093004887	dimer interface [polypeptide binding]; other site
1081093004888	hypothetical protein; Validated; Region: PRK00110
1081093004889	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1081093004890	nudix motif; other site
1081093004891	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1081093004892	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1081093004893	dimer interface [polypeptide binding]; other site
1081093004894	anticodon binding site; other site
1081093004895	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1081093004896	homodimer interface [polypeptide binding]; other site
1081093004897	motif 1; other site
1081093004898	active site
1081093004899	motif 2; other site
1081093004900	GAD domain; Region: GAD; pfam02938
1081093004901	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1081093004902	active site
1081093004903	motif 3; other site
1081093004904	hypothetical protein; Provisional; Region: PRK10302
1081093004905	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1081093004906	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093004907	S-adenosylmethionine binding site [chemical binding]; other site
1081093004908	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093004909	S-adenosylmethionine binding site [chemical binding]; other site
1081093004910	copper homeostasis protein CutC; Provisional; Region: PRK11572
1081093004911	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1081093004912	putative metal binding site [ion binding]; other site
1081093004913	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1081093004914	arginyl-tRNA synthetase; Region: argS; TIGR00456
1081093004915	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1081093004916	active site
1081093004917	HIGH motif; other site
1081093004918	KMSK motif region; other site
1081093004919	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1081093004920	tRNA binding surface [nucleotide binding]; other site
1081093004921	anticodon binding site; other site
1081093004922	penicillin-binding protein 2; Provisional; Region: PRK10795
1081093004923	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1081093004924	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1081093004925	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1081093004926	Flagellar protein FlhE; Region: FlhE; pfam06366
1081093004927	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1081093004928	FHIPEP family; Region: FHIPEP; pfam00771
1081093004929	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1081093004930	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1081093004931	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093004932	active site
1081093004933	phosphorylation site [posttranslational modification]
1081093004934	intermolecular recognition site; other site
1081093004935	dimerization interface [polypeptide binding]; other site
1081093004936	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1081093004937	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093004938	active site
1081093004939	phosphorylation site [posttranslational modification]
1081093004940	intermolecular recognition site; other site
1081093004941	dimerization interface [polypeptide binding]; other site
1081093004942	CheB methylesterase; Region: CheB_methylest; pfam01339
1081093004943	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1081093004944	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1081093004945	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093004946	S-adenosylmethionine binding site [chemical binding]; other site
1081093004947	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1081093004948	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1081093004949	dimer interface [polypeptide binding]; other site
1081093004950	ligand binding site [chemical binding]; other site
1081093004951	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093004952	dimerization interface [polypeptide binding]; other site
1081093004953	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1081093004954	dimer interface [polypeptide binding]; other site
1081093004955	putative CheW interface [polypeptide binding]; other site
1081093004956	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1081093004957	putative CheA interaction surface; other site
1081093004958	chemotaxis protein CheA; Provisional; Region: PRK10547
1081093004959	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1081093004960	putative binding surface; other site
1081093004961	active site
1081093004962	CheY binding; Region: CheY-binding; pfam09078
1081093004963	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1081093004964	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093004965	ATP binding site [chemical binding]; other site
1081093004966	Mg2+ binding site [ion binding]; other site
1081093004967	G-X-G motif; other site
1081093004968	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1081093004969	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1081093004970	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1081093004971	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1081093004972	ligand binding site [chemical binding]; other site
1081093004973	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1081093004974	flagellar motor protein MotA; Validated; Region: PRK09110
1081093004975	transcriptional activator FlhC; Provisional; Region: PRK12722
1081093004976	transcriptional activator FlhD; Provisional; Region: PRK02909
1081093004977	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1081093004978	Ligand Binding Site [chemical binding]; other site
1081093004979	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1081093004980	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1081093004981	active site
1081093004982	homotetramer interface [polypeptide binding]; other site
1081093004983	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1081093004984	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1081093004985	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1081093004986	DJ-1 family protein; Region: not_thiJ; TIGR01383
1081093004987	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1081093004988	conserved cys residue [active]
1081093004989	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1081093004990	Ferritin-like domain; Region: Ferritin; pfam00210
1081093004991	ferroxidase diiron center [ion binding]; other site
1081093004992	hypothetical protein; Provisional; Region: PRK09273
1081093004993	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
1081093004994	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
1081093004995	YecR-like lipoprotein; Region: YecR; pfam13992
1081093004996	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1081093004997	Ferritin-like domain; Region: Ferritin; pfam00210
1081093004998	ferroxidase diiron center [ion binding]; other site
1081093004999	probable metal-binding protein; Region: matur_matur; TIGR03853
1081093005000	hypothetical protein; Provisional; Region: PRK10396
1081093005001	yecA family protein; Region: ygfB_yecA; TIGR02292
1081093005002	SEC-C motif; Region: SEC-C; pfam02810
1081093005003	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
1081093005004	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1081093005005	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1081093005006	NlpC/P60 family; Region: NLPC_P60; cl17555
1081093005007	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1081093005008	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1081093005009	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1081093005010	GIY-YIG motif/motif A; other site
1081093005011	active site
1081093005012	catalytic site [active]
1081093005013	putative DNA binding site [nucleotide binding]; other site
1081093005014	metal binding site [ion binding]; metal-binding site
1081093005015	UvrB/uvrC motif; Region: UVR; pfam02151
1081093005016	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1081093005017	Helix-hairpin-helix motif; Region: HHH; pfam00633
1081093005018	response regulator; Provisional; Region: PRK09483
1081093005019	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093005020	active site
1081093005021	phosphorylation site [posttranslational modification]
1081093005022	intermolecular recognition site; other site
1081093005023	dimerization interface [polypeptide binding]; other site
1081093005024	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093005025	DNA binding residues [nucleotide binding]
1081093005026	dimerization interface [polypeptide binding]; other site
1081093005027	hypothetical protein; Provisional; Region: PRK10613
1081093005028	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1081093005029	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1081093005030	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093005031	DNA binding residues [nucleotide binding]
1081093005032	dimerization interface [polypeptide binding]; other site
1081093005033	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1081093005034	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1081093005035	Walker A/P-loop; other site
1081093005036	ATP binding site [chemical binding]; other site
1081093005037	Q-loop/lid; other site
1081093005038	ABC transporter signature motif; other site
1081093005039	Walker B; other site
1081093005040	D-loop; other site
1081093005041	H-loop/switch region; other site
1081093005042	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1081093005043	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1081093005044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093005045	dimer interface [polypeptide binding]; other site
1081093005046	conserved gate region; other site
1081093005047	putative PBP binding loops; other site
1081093005048	ABC-ATPase subunit interface; other site
1081093005049	D-cysteine desulfhydrase; Validated; Region: PRK03910
1081093005050	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1081093005051	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093005052	catalytic residue [active]
1081093005053	cystine transporter subunit; Provisional; Region: PRK11260
1081093005054	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093005055	substrate binding pocket [chemical binding]; other site
1081093005056	membrane-bound complex binding site; other site
1081093005057	hinge residues; other site
1081093005058	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1081093005059	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1081093005060	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1081093005061	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1081093005062	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1081093005063	DNA binding residues [nucleotide binding]
1081093005064	flagellin; Validated; Region: PRK08026
1081093005065	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1081093005066	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1081093005067	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1081093005068	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1081093005069	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1081093005070	flagellar protein FliS; Validated; Region: fliS; PRK05685
1081093005071	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1081093005072	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1081093005073	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1081093005074	active site
1081093005075	Na/Ca binding site [ion binding]; other site
1081093005076	catalytic site [active]
1081093005077	lipoprotein; Provisional; Region: PRK10397
1081093005078	putative inner membrane protein; Provisional; Region: PRK11099
1081093005079	Sulphur transport; Region: Sulf_transp; pfam04143
1081093005080	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1081093005081	CPxP  motif; other site
1081093005082	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1081093005083	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1081093005084	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1081093005085	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1081093005086	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1081093005087	FliG C-terminal domain; Region: FliG_C; pfam01706
1081093005088	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1081093005089	Flagellar assembly protein FliH; Region: FliH; pfam02108
1081093005090	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1081093005091	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1081093005092	Walker A motif/ATP binding site; other site
1081093005093	Walker B motif; other site
1081093005094	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1081093005095	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1081093005096	flagellar hook-length control protein; Provisional; Region: PRK10118
1081093005097	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
1081093005098	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1081093005099	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1081093005100	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1081093005101	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1081093005102	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1081093005103	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1081093005104	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1081093005105	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1081093005106	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1081093005107	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1081093005108	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093005109	DNA binding residues [nucleotide binding]
1081093005110	dimerization interface [polypeptide binding]; other site
1081093005111	hypothetical protein; Provisional; Region: PRK10708
1081093005112	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1081093005113	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1081093005114	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093005115	active site
1081093005116	motif I; other site
1081093005117	motif II; other site
1081093005118	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1081093005119	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093005120	metal binding site [ion binding]; metal-binding site
1081093005121	active site
1081093005122	I-site; other site
1081093005123	Uncharacterized small protein [Function unknown]; Region: COG5475
1081093005124	hypothetical protein; Provisional; Region: PRK10062
1081093005125	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1081093005126	EamA-like transporter family; Region: EamA; pfam00892
1081093005127	EamA-like transporter family; Region: EamA; pfam00892
1081093005128	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1081093005129	additional DNA contacts [nucleotide binding]; other site
1081093005130	mismatch recognition site; other site
1081093005131	active site
1081093005132	zinc binding site [ion binding]; other site
1081093005133	DNA intercalation site [nucleotide binding]; other site
1081093005134	DNA cytosine methylase; Provisional; Region: PRK10458
1081093005135	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1081093005136	cofactor binding site; other site
1081093005137	DNA binding site [nucleotide binding]
1081093005138	substrate interaction site [chemical binding]; other site
1081093005139	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1081093005140	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1081093005141	Zn2+ binding site [ion binding]; other site
1081093005142	Mg2+ binding site [ion binding]; other site
1081093005143	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1081093005144	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1081093005145	trimer interface [polypeptide binding]; other site
1081093005146	eyelet of channel; other site
1081093005147	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1081093005148	DNA-binding site [nucleotide binding]; DNA binding site
1081093005149	RNA-binding motif; other site
1081093005150	dsRNA-gated channel SID-1; Region: SID-1_RNA_chan; pfam13965
1081093005151	potential frameshift: common BLAST hit: gi|194451069|ref|YP_002046727.1| transposase InsF for insertion sequence IS3A/B/C/D/E/fA
1081093005152	Integrase core domain; Region: rve; pfam00665
1081093005153	Integrase core domain; Region: rve_2; pfam13333
1081093005154	HTH-like domain; Region: HTH_21; pfam13276
1081093005155	Transposase; Region: HTH_Tnp_1; cl17663
1081093005156	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1081093005157	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1081093005158	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1081093005159	Sel1-like repeats; Region: SEL1; smart00671
1081093005160	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1081093005161	RHS protein; Region: RHS; pfam03527
1081093005162	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1081093005163	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
1081093005164	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1081093005165	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1081093005166	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
1081093005167	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1081093005168	Protein of unknown function (DUF770); Region: DUF770; pfam05591
1081093005169	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
1081093005170	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
1081093005171	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1081093005172	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
1081093005173	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
1081093005174	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
1081093005175	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
1081093005176	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
1081093005177	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
1081093005178	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
1081093005179	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
1081093005180	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
1081093005181	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1081093005182	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093005183	Walker A motif; other site
1081093005184	ATP binding site [chemical binding]; other site
1081093005185	Walker B motif; other site
1081093005186	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093005187	Walker A motif; other site
1081093005188	ATP binding site [chemical binding]; other site
1081093005189	Walker B motif; other site
1081093005190	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; cl11083
1081093005191	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
1081093005192	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1081093005193	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
1081093005194	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1081093005195	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
1081093005196	AAA domain; Region: AAA_17; pfam13207
1081093005197	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
1081093005198	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
1081093005199	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1081093005200	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1081093005201	ImpA domain protein; Region: DUF3702; pfam12486
1081093005202	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
1081093005203	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1081093005204	YCII-related domain; Region: YCII; cl00999
1081093005205	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1081093005206	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1081093005207	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1081093005208	putative sialic acid transporter; Provisional; Region: PRK12307
1081093005209	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093005210	putative substrate translocation pore; other site
1081093005211	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1081093005212	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
1081093005213	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
1081093005214	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1081093005215	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1081093005216	putative active site cavity [active]
1081093005217	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
1081093005218	Na binding site [ion binding]; other site
1081093005219	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1081093005220	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1081093005221	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1081093005222	putative active site [active]
1081093005223	hypothetical protein; Provisional; Region: PRK10536
1081093005224	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1081093005225	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1081093005226	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1081093005227	Na binding site [ion binding]; other site
1081093005228	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1081093005229	Predicted transcriptional regulator [Transcription]; Region: COG3905
1081093005230	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1081093005231	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1081093005232	Glutamate binding site [chemical binding]; other site
1081093005233	NAD binding site [chemical binding]; other site
1081093005234	catalytic residues [active]
1081093005235	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1081093005236	General stress protein [General function prediction only]; Region: GsiB; COG3729
1081093005237	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1081093005238	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1081093005239	hypothetical protein; Provisional; Region: PRK10174
1081093005240	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1081093005241	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1081093005242	catalytic core [active]
1081093005243	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1081093005244	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1081093005245	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1081093005246	catalytic residues [active]
1081093005247	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
1081093005248	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1081093005249	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1081093005250	catalytic residues [active]
1081093005251	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
1081093005252	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1081093005253	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1081093005254	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1081093005255	DsbD alpha interface [polypeptide binding]; other site
1081093005256	catalytic residues [active]
1081093005257	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1081093005258	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1081093005259	HSP70 interaction site [polypeptide binding]; other site
1081093005260	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1081093005261	substrate binding site [polypeptide binding]; other site
1081093005262	dimer interface [polypeptide binding]; other site
1081093005263	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1081093005264	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
1081093005265	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
1081093005266	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1081093005267	Cupin domain; Region: Cupin_2; pfam07883
1081093005268	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093005269	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093005270	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1081093005271	putative substrate translocation pore; other site
1081093005272	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1081093005273	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1081093005274	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1081093005275	putative substrate binding pocket [chemical binding]; other site
1081093005276	trimer interface [polypeptide binding]; other site
1081093005277	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1081093005278	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1081093005279	putative active site [active]
1081093005280	putative metal binding site [ion binding]; other site
1081093005281	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
1081093005282	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
1081093005283	NAD binding site [chemical binding]; other site
1081093005284	catalytic residues [active]
1081093005285	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
1081093005286	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1081093005287	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1081093005288	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1081093005289	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1081093005290	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1081093005291	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1081093005292	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
1081093005293	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1081093005294	active site
1081093005295	homotetramer interface [polypeptide binding]; other site
1081093005296	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
1081093005297	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093005298	active site
1081093005299	phosphorylation site [posttranslational modification]
1081093005300	intermolecular recognition site; other site
1081093005301	dimerization interface [polypeptide binding]; other site
1081093005302	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093005303	DNA binding site [nucleotide binding]
1081093005304	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1081093005305	HAMP domain; Region: HAMP; pfam00672
1081093005306	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093005307	dimer interface [polypeptide binding]; other site
1081093005308	phosphorylation site [posttranslational modification]
1081093005309	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093005310	ATP binding site [chemical binding]; other site
1081093005311	Mg2+ binding site [ion binding]; other site
1081093005312	G-X-G motif; other site
1081093005313	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
1081093005314	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1081093005315	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
1081093005316	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
1081093005317	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
1081093005318	secreted effector protein PipB; Provisional; Region: PRK15197
1081093005319	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1081093005320	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1081093005321	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1081093005322	PipA protein; Region: PipA; pfam07108
1081093005323	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1081093005324	YccA-like proteins; Region: YccA_like; cd10433
1081093005325	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1081093005326	sulfur transfer protein TusE; Provisional; Region: PRK11508
1081093005327	acylphosphatase; Provisional; Region: PRK14426
1081093005328	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1081093005329	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093005330	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1081093005331	substrate binding site [chemical binding]; other site
1081093005332	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1081093005333	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1081093005334	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1081093005335	putative RNA binding site [nucleotide binding]; other site
1081093005336	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093005337	S-adenosylmethionine binding site [chemical binding]; other site
1081093005338	heat shock protein HspQ; Provisional; Region: PRK14129
1081093005339	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1081093005340	hypothetical protein; Provisional; Region: PRK03641
1081093005341	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
1081093005342	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1081093005343	active site
1081093005344	dimer interfaces [polypeptide binding]; other site
1081093005345	catalytic residues [active]
1081093005346	DNA helicase IV; Provisional; Region: helD; PRK11054
1081093005347	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1081093005348	Part of AAA domain; Region: AAA_19; pfam13245
1081093005349	Family description; Region: UvrD_C_2; pfam13538
1081093005350	Predicted membrane protein [Function unknown]; Region: COG3304
1081093005351	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1081093005352	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1081093005353	TIGR01666 family membrane protein; Region: YCCS
1081093005354	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1081093005355	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1081093005356	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
1081093005357	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1081093005358	cell division inhibitor SulA; Region: sula; TIGR00623
1081093005359	outer membrane protein A; Reviewed; Region: PRK10808
1081093005360	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1081093005361	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1081093005362	ligand binding site [chemical binding]; other site
1081093005363	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1081093005364	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1081093005365	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1081093005366	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1081093005367	active site 1 [active]
1081093005368	dimer interface [polypeptide binding]; other site
1081093005369	active site 2 [active]
1081093005370	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1081093005371	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1081093005372	paraquat-inducible protein B; Provisional; Region: PRK10807
1081093005373	mce related protein; Region: MCE; pfam02470
1081093005374	mce related protein; Region: MCE; pfam02470
1081093005375	mce related protein; Region: MCE; pfam02470
1081093005376	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1081093005377	Paraquat-inducible protein A; Region: PqiA; pfam04403
1081093005378	Paraquat-inducible protein A; Region: PqiA; pfam04403
1081093005379	ABC transporter ATPase component; Reviewed; Region: PRK11147
1081093005380	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093005381	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093005382	Walker A/P-loop; other site
1081093005383	Walker A/P-loop; other site
1081093005384	ATP binding site [chemical binding]; other site
1081093005385	ATP binding site [chemical binding]; other site
1081093005386	Q-loop/lid; other site
1081093005387	Q-loop/lid; other site
1081093005388	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093005389	ABC transporter signature motif; other site
1081093005390	Walker B; other site
1081093005391	D-loop; other site
1081093005392	ABC transporter; Region: ABC_tran_2; pfam12848
1081093005393	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093005394	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1081093005395	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1081093005396	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1081093005397	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093005398	S-adenosylmethionine binding site [chemical binding]; other site
1081093005399	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1081093005400	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1081093005401	MOSC domain; Region: MOSC; pfam03473
1081093005402	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1081093005403	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1081093005404	catalytic loop [active]
1081093005405	iron binding site [ion binding]; other site
1081093005406	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1081093005407	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1081093005408	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1081093005409	quinone interaction residues [chemical binding]; other site
1081093005410	active site
1081093005411	catalytic residues [active]
1081093005412	FMN binding site [chemical binding]; other site
1081093005413	substrate binding site [chemical binding]; other site
1081093005414	aminopeptidase N; Provisional; Region: pepN; PRK14015
1081093005415	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1081093005416	active site
1081093005417	Zn binding site [ion binding]; other site
1081093005418	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1081093005419	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1081093005420	active site
1081093005421	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1081093005422	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1081093005423	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1081093005424	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
1081093005425	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1081093005426	catalytic residue [active]
1081093005427	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1081093005428	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1081093005429	putative DNA binding site [nucleotide binding]; other site
1081093005430	putative Zn2+ binding site [ion binding]; other site
1081093005431	AsnC family; Region: AsnC_trans_reg; pfam01037
1081093005432	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1081093005433	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1081093005434	putative dimer interface [polypeptide binding]; other site
1081093005435	putative anticodon binding site; other site
1081093005436	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1081093005437	homodimer interface [polypeptide binding]; other site
1081093005438	motif 1; other site
1081093005439	motif 2; other site
1081093005440	active site
1081093005441	motif 3; other site
1081093005442	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1081093005443	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1081093005444	trimer interface [polypeptide binding]; other site
1081093005445	eyelet of channel; other site
1081093005446	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1081093005447	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093005448	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093005449	homodimer interface [polypeptide binding]; other site
1081093005450	catalytic residue [active]
1081093005451	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1081093005452	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1081093005453	Peptidase M15; Region: Peptidase_M15_3; cl01194
1081093005454	murein L,D-transpeptidase; Provisional; Region: PRK10594
1081093005455	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1081093005456	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1081093005457	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1081093005458	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
1081093005459	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1081093005460	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1081093005461	condesin subunit E; Provisional; Region: PRK05256
1081093005462	condesin subunit F; Provisional; Region: PRK05260
1081093005463	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1081093005464	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093005465	S-adenosylmethionine binding site [chemical binding]; other site
1081093005466	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1081093005467	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1081093005468	putative active site [active]
1081093005469	hypothetical protein; Provisional; Region: PRK10593
1081093005470	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1081093005471	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1081093005472	Ligand binding site; other site
1081093005473	oligomer interface; other site
1081093005474	hypothetical protein; Provisional; Region: PRK11827
1081093005475	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1081093005476	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1081093005477	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1081093005478	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1081093005479	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1081093005480	Walker A/P-loop; other site
1081093005481	ATP binding site [chemical binding]; other site
1081093005482	Q-loop/lid; other site
1081093005483	ABC transporter signature motif; other site
1081093005484	Walker B; other site
1081093005485	D-loop; other site
1081093005486	H-loop/switch region; other site
1081093005487	ComEC family competence protein; Provisional; Region: PRK11539
1081093005488	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1081093005489	Competence protein; Region: Competence; pfam03772
1081093005490	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1081093005491	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1081093005492	IHF dimer interface [polypeptide binding]; other site
1081093005493	IHF - DNA interface [nucleotide binding]; other site
1081093005494	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1081093005495	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1081093005496	RNA binding site [nucleotide binding]; other site
1081093005497	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1081093005498	RNA binding site [nucleotide binding]; other site
1081093005499	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1081093005500	RNA binding site [nucleotide binding]; other site
1081093005501	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1081093005502	RNA binding site [nucleotide binding]; other site
1081093005503	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1081093005504	RNA binding site [nucleotide binding]; other site
1081093005505	cytidylate kinase; Provisional; Region: cmk; PRK00023
1081093005506	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1081093005507	CMP-binding site; other site
1081093005508	The sites determining sugar specificity; other site
1081093005509	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1081093005510	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1081093005511	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
1081093005512	putative active site [active]
1081093005513	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1081093005514	homodimer interface [polypeptide binding]; other site
1081093005515	substrate-cofactor binding pocket; other site
1081093005516	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093005517	catalytic residue [active]
1081093005518	Predicted membrane protein [Function unknown]; Region: COG2323
1081093005519	uncharacterized domain; Region: TIGR00702
1081093005520	YcaO-like family; Region: YcaO; pfam02624
1081093005521	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1081093005522	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1081093005523	Pyruvate formate lyase 1; Region: PFL1; cd01678
1081093005524	coenzyme A binding site [chemical binding]; other site
1081093005525	active site
1081093005526	catalytic residues [active]
1081093005527	glycine loop; other site
1081093005528	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
1081093005529	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1081093005530	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093005531	FeS/SAM binding site; other site
1081093005532	inner membrane transporter YjeM; Provisional; Region: PRK15238
1081093005533	putative MFS family transporter protein; Provisional; Region: PRK03633
1081093005534	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093005535	putative substrate translocation pore; other site
1081093005536	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1081093005537	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1081093005538	4Fe-4S binding domain; Region: Fer4; pfam00037
1081093005539	seryl-tRNA synthetase; Provisional; Region: PRK05431
1081093005540	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1081093005541	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1081093005542	dimer interface [polypeptide binding]; other site
1081093005543	active site
1081093005544	motif 1; other site
1081093005545	motif 2; other site
1081093005546	motif 3; other site
1081093005547	recombination factor protein RarA; Reviewed; Region: PRK13342
1081093005548	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093005549	Walker A motif; other site
1081093005550	ATP binding site [chemical binding]; other site
1081093005551	Walker B motif; other site
1081093005552	arginine finger; other site
1081093005553	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1081093005554	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1081093005555	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1081093005556	DNA translocase FtsK; Provisional; Region: PRK10263
1081093005557	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1081093005558	DNA translocase FtsK; Provisional; Region: PRK10263
1081093005559	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1081093005560	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1081093005561	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1081093005562	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1081093005563	putative DNA binding site [nucleotide binding]; other site
1081093005564	putative Zn2+ binding site [ion binding]; other site
1081093005565	AsnC family; Region: AsnC_trans_reg; pfam01037
1081093005566	thioredoxin reductase; Provisional; Region: PRK10262
1081093005567	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1081093005568	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093005569	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1081093005570	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1081093005571	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093005572	Walker A/P-loop; other site
1081093005573	ATP binding site [chemical binding]; other site
1081093005574	Q-loop/lid; other site
1081093005575	ABC transporter signature motif; other site
1081093005576	Walker B; other site
1081093005577	D-loop; other site
1081093005578	H-loop/switch region; other site
1081093005579	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1081093005580	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1081093005581	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093005582	Walker A/P-loop; other site
1081093005583	ATP binding site [chemical binding]; other site
1081093005584	Q-loop/lid; other site
1081093005585	ABC transporter signature motif; other site
1081093005586	Walker B; other site
1081093005587	D-loop; other site
1081093005588	H-loop/switch region; other site
1081093005589	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1081093005590	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1081093005591	rRNA binding site [nucleotide binding]; other site
1081093005592	predicted 30S ribosome binding site; other site
1081093005593	LysR family transcriptional regulator; Provisional; Region: PRK14997
1081093005594	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093005595	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
1081093005596	putative effector binding pocket; other site
1081093005597	putative dimerization interface [polypeptide binding]; other site
1081093005598	Pirin-related protein [General function prediction only]; Region: COG1741
1081093005599	Pirin; Region: Pirin; pfam02678
1081093005600	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1081093005601	Isochorismatase family; Region: Isochorismatase; pfam00857
1081093005602	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1081093005603	catalytic triad [active]
1081093005604	dimer interface [polypeptide binding]; other site
1081093005605	conserved cis-peptide bond; other site
1081093005606	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1081093005607	DNA binding site [nucleotide binding]
1081093005608	active site
1081093005609	Int/Topo IB signature motif; other site
1081093005610	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1081093005611	Clp amino terminal domain; Region: Clp_N; pfam02861
1081093005612	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093005613	Walker A motif; other site
1081093005614	ATP binding site [chemical binding]; other site
1081093005615	Walker B motif; other site
1081093005616	arginine finger; other site
1081093005617	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093005618	Walker A motif; other site
1081093005619	ATP binding site [chemical binding]; other site
1081093005620	Walker B motif; other site
1081093005621	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1081093005622	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1081093005623	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1081093005624	DNA-binding site [nucleotide binding]; DNA binding site
1081093005625	RNA-binding motif; other site
1081093005626	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1081093005627	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1081093005628	Walker A/P-loop; other site
1081093005629	ATP binding site [chemical binding]; other site
1081093005630	Q-loop/lid; other site
1081093005631	ABC transporter signature motif; other site
1081093005632	Walker B; other site
1081093005633	D-loop; other site
1081093005634	H-loop/switch region; other site
1081093005635	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1081093005636	FtsX-like permease family; Region: FtsX; pfam02687
1081093005637	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1081093005638	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1081093005639	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093005640	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1081093005641	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1081093005642	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1081093005643	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1081093005644	putative active site [active]
1081093005645	putative metal-binding site [ion binding]; other site
1081093005646	Predicted membrane protein [Function unknown]; Region: COG2431
1081093005647	hybrid cluster protein; Provisional; Region: PRK05290
1081093005648	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1081093005649	ACS interaction site; other site
1081093005650	CODH interaction site; other site
1081093005651	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1081093005652	hybrid metal cluster; other site
1081093005653	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1081093005654	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1081093005655	FAD binding pocket [chemical binding]; other site
1081093005656	FAD binding motif [chemical binding]; other site
1081093005657	phosphate binding motif [ion binding]; other site
1081093005658	beta-alpha-beta structure motif; other site
1081093005659	NAD binding pocket [chemical binding]; other site
1081093005660	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1081093005661	catalytic loop [active]
1081093005662	iron binding site [ion binding]; other site
1081093005663	pyruvate dehydrogenase; Provisional; Region: PRK09124
1081093005664	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1081093005665	PYR/PP interface [polypeptide binding]; other site
1081093005666	dimer interface [polypeptide binding]; other site
1081093005667	tetramer interface [polypeptide binding]; other site
1081093005668	TPP binding site [chemical binding]; other site
1081093005669	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1081093005670	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1081093005671	TPP-binding site [chemical binding]; other site
1081093005672	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1081093005673	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1081093005674	tetramer interface [polypeptide binding]; other site
1081093005675	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093005676	catalytic residue [active]
1081093005677	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1081093005678	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1081093005679	putative NAD(P) binding site [chemical binding]; other site
1081093005680	putative active site [active]
1081093005681	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1081093005682	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1081093005683	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1081093005684	NAD(P) binding site [chemical binding]; other site
1081093005685	active site
1081093005686	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1081093005687	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1081093005688	amidase catalytic site [active]
1081093005689	Zn binding residues [ion binding]; other site
1081093005690	substrate binding site [chemical binding]; other site
1081093005691	hypothetical protein; Provisional; Region: PRK02877
1081093005692	putative lipoprotein; Provisional; Region: PRK10533
1081093005693	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1081093005694	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093005695	Walker A/P-loop; other site
1081093005696	ATP binding site [chemical binding]; other site
1081093005697	Q-loop/lid; other site
1081093005698	ABC transporter signature motif; other site
1081093005699	Walker B; other site
1081093005700	D-loop; other site
1081093005701	H-loop/switch region; other site
1081093005702	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1081093005703	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093005704	substrate binding pocket [chemical binding]; other site
1081093005705	membrane-bound complex binding site; other site
1081093005706	hinge residues; other site
1081093005707	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1081093005708	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093005709	dimer interface [polypeptide binding]; other site
1081093005710	conserved gate region; other site
1081093005711	putative PBP binding loops; other site
1081093005712	ABC-ATPase subunit interface; other site
1081093005713	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093005714	dimer interface [polypeptide binding]; other site
1081093005715	conserved gate region; other site
1081093005716	putative PBP binding loops; other site
1081093005717	ABC-ATPase subunit interface; other site
1081093005718	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1081093005719	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093005720	substrate binding pocket [chemical binding]; other site
1081093005721	membrane-bound complex binding site; other site
1081093005722	hinge residues; other site
1081093005723	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1081093005724	active site
1081093005725	P-loop; other site
1081093005726	phosphorylation site [posttranslational modification]
1081093005727	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1081093005728	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1081093005729	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093005730	S-adenosylmethionine binding site [chemical binding]; other site
1081093005731	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1081093005732	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1081093005733	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093005734	dimer interface [polypeptide binding]; other site
1081093005735	conserved gate region; other site
1081093005736	putative PBP binding loops; other site
1081093005737	ABC-ATPase subunit interface; other site
1081093005738	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093005739	dimer interface [polypeptide binding]; other site
1081093005740	conserved gate region; other site
1081093005741	putative PBP binding loops; other site
1081093005742	ABC-ATPase subunit interface; other site
1081093005743	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1081093005744	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093005745	Walker A/P-loop; other site
1081093005746	ATP binding site [chemical binding]; other site
1081093005747	Q-loop/lid; other site
1081093005748	ABC transporter signature motif; other site
1081093005749	Walker B; other site
1081093005750	D-loop; other site
1081093005751	H-loop/switch region; other site
1081093005752	TOBE domain; Region: TOBE_2; pfam08402
1081093005753	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1081093005754	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1081093005755	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1081093005756	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1081093005757	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1081093005758	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1081093005759	dimer interface [polypeptide binding]; other site
1081093005760	FMN binding site [chemical binding]; other site
1081093005761	NADPH bind site [chemical binding]; other site
1081093005762	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1081093005763	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1081093005764	GSH binding site [chemical binding]; other site
1081093005765	catalytic residues [active]
1081093005766	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1081093005767	putative transporter; Provisional; Region: PRK04972
1081093005768	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1081093005769	TrkA-C domain; Region: TrkA_C; pfam02080
1081093005770	TrkA-C domain; Region: TrkA_C; pfam02080
1081093005771	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1081093005772	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
1081093005773	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093005774	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1081093005775	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093005776	putative substrate translocation pore; other site
1081093005777	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1081093005778	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1081093005779	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093005780	active site
1081093005781	motif I; other site
1081093005782	motif II; other site
1081093005783	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093005784	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1081093005785	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093005786	putative substrate translocation pore; other site
1081093005787	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1081093005788	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1081093005789	active site
1081093005790	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1081093005791	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1081093005792	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093005793	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1081093005794	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1081093005795	putative C-terminal domain interface [polypeptide binding]; other site
1081093005796	putative GSH binding site (G-site) [chemical binding]; other site
1081093005797	putative dimer interface [polypeptide binding]; other site
1081093005798	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1081093005799	putative N-terminal domain interface [polypeptide binding]; other site
1081093005800	putative dimer interface [polypeptide binding]; other site
1081093005801	putative substrate binding pocket (H-site) [chemical binding]; other site
1081093005802	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1081093005803	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093005804	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093005805	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
1081093005806	putative dimerization interface [polypeptide binding]; other site
1081093005807	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
1081093005808	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1081093005809	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
1081093005810	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1081093005811	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1081093005812	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1081093005813	active site
1081093005814	Uncharacterized conserved protein [Function unknown]; Region: COG3777
1081093005815	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1081093005816	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1081093005817	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1081093005818	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1081093005819	Ligand binding site [chemical binding]; other site
1081093005820	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1081093005821	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1081093005822	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1081093005823	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1081093005824	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1081093005825	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093005826	FeS/SAM binding site; other site
1081093005827	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1081093005828	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1081093005829	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093005830	dimer interface [polypeptide binding]; other site
1081093005831	conserved gate region; other site
1081093005832	putative PBP binding loops; other site
1081093005833	ABC-ATPase subunit interface; other site
1081093005834	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1081093005835	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093005836	dimer interface [polypeptide binding]; other site
1081093005837	conserved gate region; other site
1081093005838	putative PBP binding loops; other site
1081093005839	ABC-ATPase subunit interface; other site
1081093005840	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1081093005841	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1081093005842	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1081093005843	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093005844	Walker A/P-loop; other site
1081093005845	ATP binding site [chemical binding]; other site
1081093005846	Q-loop/lid; other site
1081093005847	ABC transporter signature motif; other site
1081093005848	Walker B; other site
1081093005849	D-loop; other site
1081093005850	H-loop/switch region; other site
1081093005851	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1081093005852	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093005853	Walker A/P-loop; other site
1081093005854	ATP binding site [chemical binding]; other site
1081093005855	Q-loop/lid; other site
1081093005856	ABC transporter signature motif; other site
1081093005857	Walker B; other site
1081093005858	D-loop; other site
1081093005859	H-loop/switch region; other site
1081093005860	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1081093005861	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1081093005862	catalytic nucleophile [active]
1081093005863	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1081093005864	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1081093005865	dimer interface [polypeptide binding]; other site
1081093005866	putative functional site; other site
1081093005867	putative MPT binding site; other site
1081093005868	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1081093005869	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1081093005870	ATP binding site [chemical binding]; other site
1081093005871	substrate interface [chemical binding]; other site
1081093005872	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1081093005873	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093005874	FeS/SAM binding site; other site
1081093005875	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1081093005876	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1081093005877	dimer interface [polypeptide binding]; other site
1081093005878	active site
1081093005879	glycine loop; other site
1081093005880	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1081093005881	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093005882	active site
1081093005883	motif I; other site
1081093005884	motif II; other site
1081093005885	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093005886	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1081093005887	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1081093005888	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093005889	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093005890	Walker A/P-loop; other site
1081093005891	ATP binding site [chemical binding]; other site
1081093005892	ABC transporter signature motif; other site
1081093005893	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093005894	Walker B; other site
1081093005895	ABC transporter; Region: ABC_tran_2; pfam12848
1081093005896	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093005897	L,D-transpeptidase; Provisional; Region: PRK10260
1081093005898	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1081093005899	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1081093005900	transmembrane helices; other site
1081093005901	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1081093005902	manganese transport regulator MntR; Provisional; Region: PRK11050
1081093005903	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1081093005904	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1081093005905	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1081093005906	Sulfatase; Region: Sulfatase; pfam00884
1081093005907	outer membrane protein X; Provisional; Region: ompX; PRK09408
1081093005908	threonine and homoserine efflux system; Provisional; Region: PRK10532
1081093005909	EamA-like transporter family; Region: EamA; pfam00892
1081093005910	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1081093005911	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1081093005912	dimerization interface [polypeptide binding]; other site
1081093005913	DPS ferroxidase diiron center [ion binding]; other site
1081093005914	ion pore; other site
1081093005915	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1081093005916	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093005917	substrate binding pocket [chemical binding]; other site
1081093005918	membrane-bound complex binding site; other site
1081093005919	hinge residues; other site
1081093005920	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1081093005921	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093005922	dimer interface [polypeptide binding]; other site
1081093005923	conserved gate region; other site
1081093005924	putative PBP binding loops; other site
1081093005925	ABC-ATPase subunit interface; other site
1081093005926	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1081093005927	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1081093005928	Walker A/P-loop; other site
1081093005929	ATP binding site [chemical binding]; other site
1081093005930	Q-loop/lid; other site
1081093005931	ABC transporter signature motif; other site
1081093005932	Walker B; other site
1081093005933	D-loop; other site
1081093005934	H-loop/switch region; other site
1081093005935	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1081093005936	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1081093005937	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
1081093005938	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1081093005939	hypothetical protein; Provisional; Region: PRK11019
1081093005940	hypothetical protein; Provisional; Region: PRK10259
1081093005941	glycosyl transferase family protein; Provisional; Region: PRK08136
1081093005942	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1081093005943	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1081093005944	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1081093005945	ATP binding site [chemical binding]; other site
1081093005946	Mg++ binding site [ion binding]; other site
1081093005947	motif III; other site
1081093005948	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093005949	nucleotide binding region [chemical binding]; other site
1081093005950	ATP-binding site [chemical binding]; other site
1081093005951	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1081093005952	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093005953	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1081093005954	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1081093005955	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1081093005956	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093005957	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1081093005958	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1081093005959	Walker A/P-loop; other site
1081093005960	ATP binding site [chemical binding]; other site
1081093005961	Q-loop/lid; other site
1081093005962	ABC transporter signature motif; other site
1081093005963	Walker B; other site
1081093005964	D-loop; other site
1081093005965	H-loop/switch region; other site
1081093005966	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1081093005967	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1081093005968	Walker A/P-loop; other site
1081093005969	ATP binding site [chemical binding]; other site
1081093005970	Q-loop/lid; other site
1081093005971	ABC transporter signature motif; other site
1081093005972	Walker B; other site
1081093005973	D-loop; other site
1081093005974	H-loop/switch region; other site
1081093005975	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1081093005976	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1081093005977	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1081093005978	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1081093005979	putative catalytic site [active]
1081093005980	putative metal binding site [ion binding]; other site
1081093005981	putative phosphate binding site [ion binding]; other site
1081093005982	cardiolipin synthase 2; Provisional; Region: PRK11263
1081093005983	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1081093005984	putative active site [active]
1081093005985	catalytic site [active]
1081093005986	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1081093005987	putative active site [active]
1081093005988	catalytic site [active]
1081093005989	Predicted integral membrane protein [Function unknown]; Region: COG0392
1081093005990	BAX inhibitor (BI)-1/YccA-like protein family; Region: BI-1-like; cl00473
1081093005991	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1081093005992	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1081093005993	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1081093005994	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1081093005995	MoaE homodimer interface [polypeptide binding]; other site
1081093005996	MoaD interaction [polypeptide binding]; other site
1081093005997	active site residues [active]
1081093005998	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1081093005999	MoaE interaction surface [polypeptide binding]; other site
1081093006000	MoeB interaction surface [polypeptide binding]; other site
1081093006001	thiocarboxylated glycine; other site
1081093006002	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1081093006003	trimer interface [polypeptide binding]; other site
1081093006004	dimer interface [polypeptide binding]; other site
1081093006005	putative active site [active]
1081093006006	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1081093006007	MPT binding site; other site
1081093006008	trimer interface [polypeptide binding]; other site
1081093006009	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1081093006010	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093006011	FeS/SAM binding site; other site
1081093006012	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1081093006013	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1081093006014	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1081093006015	putative substrate binding pocket [chemical binding]; other site
1081093006016	dimer interface [polypeptide binding]; other site
1081093006017	phosphate binding site [ion binding]; other site
1081093006018	excinuclease ABC subunit B; Provisional; Region: PRK05298
1081093006019	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1081093006020	ATP binding site [chemical binding]; other site
1081093006021	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093006022	nucleotide binding region [chemical binding]; other site
1081093006023	ATP-binding site [chemical binding]; other site
1081093006024	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1081093006025	UvrB/uvrC motif; Region: UVR; pfam02151
1081093006026	AAA domain; Region: AAA_26; pfam13500
1081093006027	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1081093006028	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1081093006029	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093006030	S-adenosylmethionine binding site [chemical binding]; other site
1081093006031	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1081093006032	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1081093006033	substrate-cofactor binding pocket; other site
1081093006034	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093006035	catalytic residue [active]
1081093006036	biotin synthase; Provisional; Region: PRK15108
1081093006037	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093006038	FeS/SAM binding site; other site
1081093006039	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1081093006040	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1081093006041	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1081093006042	inhibitor-cofactor binding pocket; inhibition site
1081093006043	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093006044	catalytic residue [active]
1081093006045	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1081093006046	substrate binding site [chemical binding]; other site
1081093006047	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1081093006048	active sites [active]
1081093006049	tetramer interface [polypeptide binding]; other site
1081093006050	urocanate hydratase; Provisional; Region: PRK05414
1081093006051	histidine utilization repressor; Provisional; Region: PRK14999
1081093006052	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093006053	DNA-binding site [nucleotide binding]; DNA binding site
1081093006054	UTRA domain; Region: UTRA; pfam07702
1081093006055	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1081093006056	putative active site [active]
1081093006057	putative metal binding site [ion binding]; other site
1081093006058	imidazolonepropionase; Validated; Region: PRK09356
1081093006059	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1081093006060	active site
1081093006061	acyl-CoA thioesterase; Provisional; Region: PRK10531
1081093006062	putative pectinesterase; Region: PLN02432; cl01911
1081093006063	6-phosphogluconolactonase; Provisional; Region: PRK11028
1081093006064	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1081093006065	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093006066	active site
1081093006067	motif I; other site
1081093006068	motif II; other site
1081093006069	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093006070	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1081093006071	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093006072	Walker A/P-loop; other site
1081093006073	ATP binding site [chemical binding]; other site
1081093006074	Q-loop/lid; other site
1081093006075	ABC transporter signature motif; other site
1081093006076	Walker B; other site
1081093006077	D-loop; other site
1081093006078	H-loop/switch region; other site
1081093006079	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1081093006080	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1081093006081	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093006082	dimer interface [polypeptide binding]; other site
1081093006083	conserved gate region; other site
1081093006084	putative PBP binding loops; other site
1081093006085	ABC-ATPase subunit interface; other site
1081093006086	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1081093006087	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093006088	substrate binding pocket [chemical binding]; other site
1081093006089	membrane-bound complex binding site; other site
1081093006090	hinge residues; other site
1081093006091	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1081093006092	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1081093006093	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1081093006094	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1081093006095	TOBE domain; Region: TOBE; pfam03459
1081093006096	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1081093006097	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093006098	Walker A/P-loop; other site
1081093006099	ATP binding site [chemical binding]; other site
1081093006100	Q-loop/lid; other site
1081093006101	ABC transporter signature motif; other site
1081093006102	Walker B; other site
1081093006103	D-loop; other site
1081093006104	H-loop/switch region; other site
1081093006105	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093006106	Walker A/P-loop; other site
1081093006107	ATP binding site [chemical binding]; other site
1081093006108	Q-loop/lid; other site
1081093006109	ABC transporter signature motif; other site
1081093006110	Walker B; other site
1081093006111	D-loop; other site
1081093006112	H-loop/switch region; other site
1081093006113	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
1081093006114	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1081093006115	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1081093006116	NAD binding site [chemical binding]; other site
1081093006117	homodimer interface [polypeptide binding]; other site
1081093006118	active site
1081093006119	substrate binding site [chemical binding]; other site
1081093006120	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1081093006121	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1081093006122	dimer interface [polypeptide binding]; other site
1081093006123	active site
1081093006124	galactokinase; Provisional; Region: PRK05101
1081093006125	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1081093006126	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1081093006127	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1081093006128	active site
1081093006129	catalytic residues [active]
1081093006130	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1081093006131	catalytic core [active]
1081093006132	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1081093006133	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1081093006134	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1081093006135	Walker A/P-loop; other site
1081093006136	ATP binding site [chemical binding]; other site
1081093006137	Q-loop/lid; other site
1081093006138	ABC transporter signature motif; other site
1081093006139	Walker B; other site
1081093006140	D-loop; other site
1081093006141	H-loop/switch region; other site
1081093006142	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1081093006143	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1081093006144	dimer interface [polypeptide binding]; other site
1081093006145	putative PBP binding regions; other site
1081093006146	ABC-ATPase subunit  interface; other site
1081093006147	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1081093006148	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1081093006149	Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion]; Region: COG5016
1081093006150	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1081093006151	active site
1081093006152	catalytic residues [active]
1081093006153	metal binding site [ion binding]; metal-binding site
1081093006154	homodimer binding site [polypeptide binding]; other site
1081093006155	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1081093006156	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1081093006157	transmembrane helices; other site
1081093006158	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093006159	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093006160	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1081093006161	dimerization interface [polypeptide binding]; other site
1081093006162	fumarate hydratase; Provisional; Region: PRK06246
1081093006163	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain [Energy production and conversion]; Region: FumA; COG1838
1081093006164	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1081093006165	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1081093006166	YbgS-like protein; Region: YbgS; pfam13985
1081093006167	zinc transporter ZitB; Provisional; Region: PRK03557
1081093006168	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1081093006169	quinolinate synthetase; Provisional; Region: PRK09375
1081093006170	tol-pal system protein YbgF; Provisional; Region: PRK10803
1081093006171	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1081093006172	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1081093006173	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1081093006174	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1081093006175	ligand binding site [chemical binding]; other site
1081093006176	translocation protein TolB; Provisional; Region: tolB; PRK03629
1081093006177	TolB amino-terminal domain; Region: TolB_N; pfam04052
1081093006178	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1081093006179	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1081093006180	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1081093006181	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1081093006182	TolA C-terminal; Region: TolA; pfam06519
1081093006183	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1081093006184	colicin uptake protein TolR; Provisional; Region: PRK11024
1081093006185	colicin uptake protein TolQ; Provisional; Region: PRK10801
1081093006186	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1081093006187	active site
1081093006188	hypothetical protein; Provisional; Region: PRK10588
1081093006189	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
1081093006190	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1081093006191	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1081093006192	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1081093006193	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1081093006194	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1081093006195	CoA binding domain; Region: CoA_binding; smart00881
1081093006196	CoA-ligase; Region: Ligase_CoA; pfam00549
1081093006197	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1081093006198	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1081093006199	CoA-ligase; Region: Ligase_CoA; pfam00549
1081093006200	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1081093006201	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1081093006202	E3 interaction surface; other site
1081093006203	lipoyl attachment site [posttranslational modification]; other site
1081093006204	e3 binding domain; Region: E3_binding; pfam02817
1081093006205	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1081093006206	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1081093006207	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1081093006208	TPP-binding site [chemical binding]; other site
1081093006209	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1081093006210	dimer interface [polypeptide binding]; other site
1081093006211	PYR/PP interface [polypeptide binding]; other site
1081093006212	TPP binding site [chemical binding]; other site
1081093006213	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1081093006214	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1081093006215	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1081093006216	L-aspartate oxidase; Provisional; Region: PRK06175
1081093006217	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1081093006218	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1081093006219	SdhC subunit interface [polypeptide binding]; other site
1081093006220	proximal heme binding site [chemical binding]; other site
1081093006221	cardiolipin binding site; other site
1081093006222	Iron-sulfur protein interface; other site
1081093006223	proximal quinone binding site [chemical binding]; other site
1081093006224	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1081093006225	Iron-sulfur protein interface; other site
1081093006226	proximal quinone binding site [chemical binding]; other site
1081093006227	SdhD (CybS) interface [polypeptide binding]; other site
1081093006228	proximal heme binding site [chemical binding]; other site
1081093006229	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1081093006230	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1081093006231	dimer interface [polypeptide binding]; other site
1081093006232	active site
1081093006233	citrylCoA binding site [chemical binding]; other site
1081093006234	NADH binding [chemical binding]; other site
1081093006235	cationic pore residues; other site
1081093006236	oxalacetate/citrate binding site [chemical binding]; other site
1081093006237	coenzyme A binding site [chemical binding]; other site
1081093006238	catalytic triad [active]
1081093006239	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1081093006240	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1081093006241	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1081093006242	endonuclease VIII; Provisional; Region: PRK10445
1081093006243	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
1081093006244	DNA binding site [nucleotide binding]
1081093006245	catalytic residue [active]
1081093006246	putative catalytic residues [active]
1081093006247	H2TH interface [polypeptide binding]; other site
1081093006248	intercalation triad [nucleotide binding]; other site
1081093006249	substrate specificity determining residue; other site
1081093006250	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1081093006251	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1081093006252	LamB/YcsF family protein; Provisional; Region: PRK05406
1081093006253	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1081093006254	Allophanate hydrolase subunit 1; Region: AHS1; smart00796
1081093006255	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1081093006256	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1081093006257	metal-binding protein; Provisional; Region: PRK10799
1081093006258	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1081093006259	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093006260	putative substrate translocation pore; other site
1081093006261	POT family; Region: PTR2; pfam00854
1081093006262	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1081093006263	DNA photolyase; Region: DNA_photolyase; pfam00875
1081093006264	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1081093006265	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1081093006266	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1081093006267	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1081093006268	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1081093006269	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093006270	active site
1081093006271	phosphorylation site [posttranslational modification]
1081093006272	intermolecular recognition site; other site
1081093006273	dimerization interface [polypeptide binding]; other site
1081093006274	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093006275	DNA binding site [nucleotide binding]
1081093006276	ornithine decarboxylase; Provisional; Region: PRK13578
1081093006277	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1081093006278	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1081093006279	homodimer interface [polypeptide binding]; other site
1081093006280	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093006281	catalytic residue [active]
1081093006282	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1081093006283	putrescine transporter; Provisional; Region: potE; PRK10655
1081093006284	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
1081093006285	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1081093006286	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1081093006287	active site
1081093006288	substrate binding site [chemical binding]; other site
1081093006289	metal binding site [ion binding]; metal-binding site
1081093006290	replication initiation regulator SeqA; Provisional; Region: PRK11187
1081093006291	acyl-CoA esterase; Provisional; Region: PRK10673
1081093006292	PGAP1-like protein; Region: PGAP1; pfam07819
1081093006293	LexA regulated protein; Provisional; Region: PRK11675
1081093006294	flavodoxin FldA; Validated; Region: PRK09267
1081093006295	ferric uptake regulator; Provisional; Region: fur; PRK09462
1081093006296	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1081093006297	metal binding site 2 [ion binding]; metal-binding site
1081093006298	putative DNA binding helix; other site
1081093006299	metal binding site 1 [ion binding]; metal-binding site
1081093006300	dimer interface [polypeptide binding]; other site
1081093006301	structural Zn2+ binding site [ion binding]; other site
1081093006302	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093006303	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093006304	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1081093006305	putative dimerization interface [polypeptide binding]; other site
1081093006306	tricarballylate dehydrogenase; Validated; Region: PRK08274
1081093006307	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1081093006308	tricarballylate utilization protein B; Provisional; Region: PRK15033
1081093006309	citrate-proton symporter; Provisional; Region: PRK15075
1081093006310	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093006311	putative substrate translocation pore; other site
1081093006312	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1081093006313	YbfN-like lipoprotein; Region: YbfN; pfam13982
1081093006314	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1081093006315	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1081093006316	active site
1081093006317	HIGH motif; other site
1081093006318	nucleotide binding site [chemical binding]; other site
1081093006319	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1081093006320	KMSKS motif; other site
1081093006321	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1081093006322	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1081093006323	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1081093006324	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1081093006325	active site turn [active]
1081093006326	phosphorylation site [posttranslational modification]
1081093006327	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1081093006328	HPr interaction site; other site
1081093006329	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1081093006330	active site
1081093006331	phosphorylation site [posttranslational modification]
1081093006332	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1081093006333	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1081093006334	active site
1081093006335	trimer interface [polypeptide binding]; other site
1081093006336	allosteric site; other site
1081093006337	active site lid [active]
1081093006338	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1081093006339	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1081093006340	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1081093006341	active site
1081093006342	dimer interface [polypeptide binding]; other site
1081093006343	MarR family; Region: MarR; pfam01047
1081093006344	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1081093006345	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1081093006346	nucleotide binding site [chemical binding]; other site
1081093006347	UMP phosphatase; Provisional; Region: PRK10444
1081093006348	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093006349	active site
1081093006350	motif I; other site
1081093006351	motif II; other site
1081093006352	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093006353	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1081093006354	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1081093006355	active site
1081093006356	dimer interface [polypeptide binding]; other site
1081093006357	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1081093006358	Ligand Binding Site [chemical binding]; other site
1081093006359	Molecular Tunnel; other site
1081093006360	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1081093006361	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1081093006362	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1081093006363	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1081093006364	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093006365	FeS/SAM binding site; other site
1081093006366	TRAM domain; Region: TRAM; pfam01938
1081093006367	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1081093006368	PhoH-like protein; Region: PhoH; pfam02562
1081093006369	metal-binding heat shock protein; Provisional; Region: PRK00016
1081093006370	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1081093006371	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1081093006372	Transporter associated domain; Region: CorC_HlyC; smart01091
1081093006373	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1081093006374	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1081093006375	putative active site [active]
1081093006376	catalytic triad [active]
1081093006377	putative dimer interface [polypeptide binding]; other site
1081093006378	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1081093006379	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093006380	substrate binding pocket [chemical binding]; other site
1081093006381	membrane-bound complex binding site; other site
1081093006382	hinge residues; other site
1081093006383	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1081093006384	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093006385	dimer interface [polypeptide binding]; other site
1081093006386	conserved gate region; other site
1081093006387	putative PBP binding loops; other site
1081093006388	ABC-ATPase subunit interface; other site
1081093006389	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1081093006390	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093006391	dimer interface [polypeptide binding]; other site
1081093006392	conserved gate region; other site
1081093006393	putative PBP binding loops; other site
1081093006394	ABC-ATPase subunit interface; other site
1081093006395	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1081093006396	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1081093006397	Walker A/P-loop; other site
1081093006398	ATP binding site [chemical binding]; other site
1081093006399	Q-loop/lid; other site
1081093006400	ABC transporter signature motif; other site
1081093006401	Walker B; other site
1081093006402	D-loop; other site
1081093006403	H-loop/switch region; other site
1081093006404	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1081093006405	active site
1081093006406	tetramer interface [polypeptide binding]; other site
1081093006407	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
1081093006408	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
1081093006409	nucleotide binding site [chemical binding]; other site
1081093006410	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1081093006411	SBD interface [polypeptide binding]; other site
1081093006412	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
1081093006413	HSP70 interaction site [polypeptide binding]; other site
1081093006414	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1081093006415	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1081093006416	HSP70 interaction site [polypeptide binding]; other site
1081093006417	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
1081093006418	hypothetical protein; Provisional; Region: PRK11032
1081093006419	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1081093006420	Propionate catabolism activator; Region: PrpR_N; pfam06506
1081093006421	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
1081093006422	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093006423	Walker A motif; other site
1081093006424	ATP binding site [chemical binding]; other site
1081093006425	Walker B motif; other site
1081093006426	arginine finger; other site
1081093006427	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
1081093006428	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1081093006429	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1081093006430	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1081093006431	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1081093006432	HIGH motif; other site
1081093006433	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1081093006434	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1081093006435	active site
1081093006436	KMSKS motif; other site
1081093006437	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1081093006438	tRNA binding surface [nucleotide binding]; other site
1081093006439	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1081093006440	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1081093006441	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1081093006442	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1081093006443	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1081093006444	active site
1081093006445	(T/H)XGH motif; other site
1081093006446	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
1081093006447	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093006448	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093006449	homodimer interface [polypeptide binding]; other site
1081093006450	catalytic residue [active]
1081093006451	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1081093006452	catalytic core [active]
1081093006453	ribosome-associated protein; Provisional; Region: PRK11538
1081093006454	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1081093006455	penicillin-binding protein 2; Provisional; Region: PRK10795
1081093006456	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1081093006457	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1081093006458	cell wall shape-determining protein; Provisional; Region: PRK10794
1081093006459	rare lipoprotein A; Provisional; Region: PRK10672
1081093006460	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1081093006461	Sporulation related domain; Region: SPOR; pfam05036
1081093006462	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1081093006463	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1081093006464	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1081093006465	hypothetical protein; Provisional; Region: PRK04998
1081093006466	lipoate-protein ligase B; Provisional; Region: PRK14342
1081093006467	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1081093006468	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093006469	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1081093006470	substrate binding pocket [chemical binding]; other site
1081093006471	dimerization interface [polypeptide binding]; other site
1081093006472	lipoyl synthase; Provisional; Region: PRK05481
1081093006473	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093006474	FeS/SAM binding site; other site
1081093006475	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1081093006476	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1081093006477	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1081093006478	putative active site [active]
1081093006479	catalytic triad [active]
1081093006480	putative dimer interface [polypeptide binding]; other site
1081093006481	chromosome condensation membrane protein; Provisional; Region: PRK14196
1081093006482	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1081093006483	DNA-binding site [nucleotide binding]; DNA binding site
1081093006484	RNA-binding motif; other site
1081093006485	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1081093006486	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1081093006487	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1081093006488	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1081093006489	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093006490	active site
1081093006491	phosphorylation site [posttranslational modification]
1081093006492	intermolecular recognition site; other site
1081093006493	dimerization interface [polypeptide binding]; other site
1081093006494	Transcriptional regulator; Region: CitT; pfam12431
1081093006495	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1081093006496	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1081093006497	putative active site [active]
1081093006498	heme pocket [chemical binding]; other site
1081093006499	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093006500	ATP binding site [chemical binding]; other site
1081093006501	Mg2+ binding site [ion binding]; other site
1081093006502	G-X-G motif; other site
1081093006503	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1081093006504	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1081093006505	putative active site [active]
1081093006506	(T/H)XGH motif; other site
1081093006507	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1081093006508	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1081093006509	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1081093006510	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1081093006511	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1081093006512	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
1081093006513	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1081093006514	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1081093006515	transmembrane helices; other site
1081093006516	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1081093006517	B1 nucleotide binding pocket [chemical binding]; other site
1081093006518	B2 nucleotide binding pocket [chemical binding]; other site
1081093006519	CAS motifs; other site
1081093006520	active site
1081093006521	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1081093006522	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1081093006523	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1081093006524	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1081093006525	NAD binding site [chemical binding]; other site
1081093006526	catalytic Zn binding site [ion binding]; other site
1081093006527	structural Zn binding site [ion binding]; other site
1081093006528	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1081093006529	Ligand Binding Site [chemical binding]; other site
1081093006530	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1081093006531	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1081093006532	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1081093006533	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
1081093006534	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1081093006535	putative molybdopterin cofactor binding site [chemical binding]; other site
1081093006536	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
1081093006537	molybdopterin cofactor binding site; other site
1081093006538	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1081093006539	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1081093006540	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1081093006541	catalytic residue [active]
1081093006542	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1081093006543	catalytic residues [active]
1081093006544	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1081093006545	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093006546	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1081093006547	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1081093006548	dimer interface [polypeptide binding]; other site
1081093006549	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1081093006550	catalytic triad [active]
1081093006551	peroxidatic and resolving cysteines [active]
1081093006552	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1081093006553	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1081093006554	dimerization domain [polypeptide binding]; other site
1081093006555	dimer interface [polypeptide binding]; other site
1081093006556	catalytic residues [active]
1081093006557	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1081093006558	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093006559	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093006560	dimerization interface [polypeptide binding]; other site
1081093006561	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1081093006562	ParB-like nuclease domain; Region: ParBc; pfam02195
1081093006563	methionine aminotransferase; Validated; Region: PRK09082
1081093006564	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093006565	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093006566	homodimer interface [polypeptide binding]; other site
1081093006567	catalytic residue [active]
1081093006568	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1081093006569	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1081093006570	putative active site [active]
1081093006571	metal binding site [ion binding]; metal-binding site
1081093006572	Uncharacterized small protein [Function unknown]; Region: COG2879
1081093006573	carbon starvation protein A; Provisional; Region: PRK15015
1081093006574	Carbon starvation protein CstA; Region: CstA; pfam02554
1081093006575	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1081093006576	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1081093006577	CoenzymeA binding site [chemical binding]; other site
1081093006578	subunit interaction site [polypeptide binding]; other site
1081093006579	PHB binding site; other site
1081093006580	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1081093006581	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1081093006582	putative NAD(P) binding site [chemical binding]; other site
1081093006583	active site
1081093006584	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1081093006585	hydrophobic substrate binding pocket; other site
1081093006586	Isochorismatase family; Region: Isochorismatase; pfam00857
1081093006587	active site
1081093006588	conserved cis-peptide bond; other site
1081093006589	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1081093006590	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1081093006591	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1081093006592	acyl-activating enzyme (AAE) consensus motif; other site
1081093006593	active site
1081093006594	AMP binding site [chemical binding]; other site
1081093006595	substrate binding site [chemical binding]; other site
1081093006596	isochorismate synthase EntC; Provisional; Region: PRK15016
1081093006597	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1081093006598	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1081093006599	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1081093006600	siderophore binding site; other site
1081093006601	enterobactin exporter EntS; Provisional; Region: PRK10489
1081093006602	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093006603	putative substrate translocation pore; other site
1081093006604	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1081093006605	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1081093006606	ABC-ATPase subunit  interface; other site
1081093006607	dimer interface [polypeptide binding]; other site
1081093006608	putative PBP binding regions; other site
1081093006609	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1081093006610	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1081093006611	ABC-ATPase subunit  interface; other site
1081093006612	dimer interface [polypeptide binding]; other site
1081093006613	putative PBP binding regions; other site
1081093006614	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1081093006615	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1081093006616	Walker A/P-loop; other site
1081093006617	ATP binding site [chemical binding]; other site
1081093006618	Q-loop/lid; other site
1081093006619	ABC transporter signature motif; other site
1081093006620	Walker B; other site
1081093006621	D-loop; other site
1081093006622	H-loop/switch region; other site
1081093006623	LPS O-antigen length regulator; Provisional; Region: PRK10381
1081093006624	Chain length determinant protein; Region: Wzz; pfam02706
1081093006625	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
1081093006626	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
1081093006627	acyl-activating enzyme (AAE) consensus motif; other site
1081093006628	AMP binding site [chemical binding]; other site
1081093006629	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
1081093006630	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
1081093006631	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1081093006632	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1081093006633	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1081093006634	outer membrane receptor FepA; Provisional; Region: PRK13524
1081093006635	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1081093006636	N-terminal plug; other site
1081093006637	ligand-binding site [chemical binding]; other site
1081093006638	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1081093006639	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1081093006640	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1081093006641	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1081093006642	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1081093006643	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1081093006644	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093006645	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1081093006646	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093006647	hypothetical protein; Provisional; Region: PRK10250
1081093006648	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1081093006649	dimer interface [polypeptide binding]; other site
1081093006650	FMN binding site [chemical binding]; other site
1081093006651	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1081093006652	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1081093006653	active site
1081093006654	oxyanion hole [active]
1081093006655	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1081093006656	catalytic triad [active]
1081093006657	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1081093006658	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1081093006659	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1081093006660	phenylalanine transporter; Provisional; Region: PRK10249
1081093006661	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
1081093006662	Predicted membrane protein [Function unknown]; Region: COG3059
1081093006663	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093006664	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1081093006665	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093006666	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1081093006667	Cupin; Region: Cupin_6; pfam12852
1081093006668	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1081093006669	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093006670	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093006671	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1081093006672	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093006673	ATP binding site [chemical binding]; other site
1081093006674	Mg2+ binding site [ion binding]; other site
1081093006675	G-X-G motif; other site
1081093006676	Predicted membrane protein [Function unknown]; Region: COG2246
1081093006677	GtrA-like protein; Region: GtrA; pfam04138
1081093006678	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1081093006679	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1081093006680	Ligand binding site; other site
1081093006681	Putative Catalytic site; other site
1081093006682	DXD motif; other site
1081093006683	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1081093006684	Transposase; Region: HTH_Tnp_1; pfam01527
1081093006685	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
1081093006686	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093006687	DNA binding residues [nucleotide binding]
1081093006688	dimerization interface [polypeptide binding]; other site
1081093006689	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1081093006690	transcriptional regulator FimZ; Provisional; Region: PRK09935
1081093006691	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093006692	active site
1081093006693	phosphorylation site [posttranslational modification]
1081093006694	intermolecular recognition site; other site
1081093006695	dimerization interface [polypeptide binding]; other site
1081093006696	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093006697	DNA binding residues [nucleotide binding]
1081093006698	dimerization interface [polypeptide binding]; other site
1081093006699	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1081093006700	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1081093006701	outer membrane usher protein FimD; Provisional; Region: PRK15198
1081093006702	PapC N-terminal domain; Region: PapC_N; pfam13954
1081093006703	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1081093006704	PapC C-terminal domain; Region: PapC_C; pfam13953
1081093006705	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1081093006706	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093006707	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093006708	fimbrial protein FimI; Provisional; Region: PRK15200
1081093006709	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
1081093006710	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1081093006711	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1081093006712	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1081093006713	homodimer interface [polypeptide binding]; other site
1081093006714	NADP binding site [chemical binding]; other site
1081093006715	substrate binding site [chemical binding]; other site
1081093006716	ribosome-associated protein; Provisional; Region: PRK11507
1081093006717	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1081093006718	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
1081093006719	Uncharacterized protein conserved in bacteria (DUF2145); Region: DUF2145; pfam09916
1081093006720	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1081093006721	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1081093006722	active site
1081093006723	HIGH motif; other site
1081093006724	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1081093006725	KMSKS motif; other site
1081093006726	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1081093006727	tRNA binding surface [nucleotide binding]; other site
1081093006728	anticodon binding site; other site
1081093006729	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1081093006730	substrate binding site [chemical binding]; other site
1081093006731	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1081093006732	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1081093006733	putative active site [active]
1081093006734	putative metal binding site [ion binding]; other site
1081093006735	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1081093006736	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1081093006737	ATP-grasp domain; Region: ATP-grasp; pfam02222
1081093006738	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1081093006739	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1081093006740	putative substrate binding site [chemical binding]; other site
1081093006741	nucleotide binding site [chemical binding]; other site
1081093006742	nucleotide binding site [chemical binding]; other site
1081093006743	homodimer interface [polypeptide binding]; other site
1081093006744	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1081093006745	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
1081093006746	membrane protein FdrA; Validated; Region: PRK06091
1081093006747	CoA binding domain; Region: CoA_binding; pfam02629
1081093006748	CoA-ligase; Region: Ligase_CoA; pfam00549
1081093006749	allantoate amidohydrolase; Region: AllC; TIGR03176
1081093006750	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
1081093006751	active site
1081093006752	metal binding site [ion binding]; metal-binding site
1081093006753	dimer interface [polypeptide binding]; other site
1081093006754	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
1081093006755	Mif2/CENP-C like; Region: Mif2; pfam11699
1081093006756	Cupin domain; Region: Cupin_2; pfam07883
1081093006757	glycerate kinase II; Provisional; Region: PRK09932
1081093006758	allantoinase; Provisional; Region: PRK08044
1081093006759	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
1081093006760	active site
1081093006761	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily, YbbW-like; solute-binding domain; Region: SLC-NCS1sbd_YbbW-like; cd11485
1081093006762	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1081093006763	Na binding site [ion binding]; other site
1081093006764	putative substrate binding site [chemical binding]; other site
1081093006765	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093006766	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1081093006767	putative substrate translocation pore; other site
1081093006768	tartronate semialdehyde reductase; Provisional; Region: PRK15059
1081093006769	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1081093006770	hydroxypyruvate isomerase; Provisional; Region: PRK09997
1081093006771	glyoxylate carboligase; Provisional; Region: PRK11269
1081093006772	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1081093006773	PYR/PP interface [polypeptide binding]; other site
1081093006774	dimer interface [polypeptide binding]; other site
1081093006775	TPP binding site [chemical binding]; other site
1081093006776	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1081093006777	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
1081093006778	TPP-binding site [chemical binding]; other site
1081093006779	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
1081093006780	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1081093006781	Bacterial transcriptional regulator; Region: IclR; pfam01614
1081093006782	ureidoglycolate hydrolase; Provisional; Region: PRK03606
1081093006783	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
1081093006784	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
1081093006785	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093006786	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093006787	dimerization interface [polypeptide binding]; other site
1081093006788	Predicted ATPase [General function prediction only]; Region: COG2603
1081093006789	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1081093006790	active site residue [active]
1081093006791	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093006792	dimer interface [polypeptide binding]; other site
1081093006793	conserved gate region; other site
1081093006794	ABC-ATPase subunit interface; other site
1081093006795	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1081093006796	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1081093006797	Walker A/P-loop; other site
1081093006798	ATP binding site [chemical binding]; other site
1081093006799	Q-loop/lid; other site
1081093006800	ABC transporter signature motif; other site
1081093006801	Walker B; other site
1081093006802	D-loop; other site
1081093006803	H-loop/switch region; other site
1081093006804	NIL domain; Region: NIL; pfam09383
1081093006805	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1081093006806	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1081093006807	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1081093006808	FtsX-like permease family; Region: FtsX; pfam02687
1081093006809	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1081093006810	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1081093006811	Walker A/P-loop; other site
1081093006812	ATP binding site [chemical binding]; other site
1081093006813	Q-loop/lid; other site
1081093006814	ABC transporter signature motif; other site
1081093006815	Walker B; other site
1081093006816	D-loop; other site
1081093006817	H-loop/switch region; other site
1081093006818	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1081093006819	active site
1081093006820	catalytic triad [active]
1081093006821	oxyanion hole [active]
1081093006822	switch loop; other site
1081093006823	oxidoreductase; Provisional; Region: PRK08017
1081093006824	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1081093006825	NADP binding site [chemical binding]; other site
1081093006826	active site
1081093006827	steroid binding site; other site
1081093006828	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1081093006829	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1081093006830	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1081093006831	Walker A/P-loop; other site
1081093006832	ATP binding site [chemical binding]; other site
1081093006833	Q-loop/lid; other site
1081093006834	ABC transporter signature motif; other site
1081093006835	Walker B; other site
1081093006836	D-loop; other site
1081093006837	H-loop/switch region; other site
1081093006838	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1081093006839	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1081093006840	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1081093006841	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1081093006842	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1081093006843	DNA binding residues [nucleotide binding]
1081093006844	dimer interface [polypeptide binding]; other site
1081093006845	copper binding site [ion binding]; other site
1081093006846	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1081093006847	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
1081093006848	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1081093006849	putative deacylase active site [active]
1081093006850	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1081093006851	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1081093006852	active site
1081093006853	metal binding site [ion binding]; metal-binding site
1081093006854	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1081093006855	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093006856	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1081093006857	putative substrate translocation pore; other site
1081093006858	putative cation:proton antiport protein; Provisional; Region: PRK10669
1081093006859	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1081093006860	TrkA-N domain; Region: TrkA_N; pfam02254
1081093006861	inosine/guanosine kinase; Provisional; Region: PRK15074
1081093006862	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093006863	ferrochelatase; Reviewed; Region: hemH; PRK00035
1081093006864	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1081093006865	C-terminal domain interface [polypeptide binding]; other site
1081093006866	active site
1081093006867	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1081093006868	active site
1081093006869	N-terminal domain interface [polypeptide binding]; other site
1081093006870	adenylate kinase; Reviewed; Region: adk; PRK00279
1081093006871	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1081093006872	AMP-binding site [chemical binding]; other site
1081093006873	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1081093006874	heat shock protein 90; Provisional; Region: PRK05218
1081093006875	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093006876	ATP binding site [chemical binding]; other site
1081093006877	Mg2+ binding site [ion binding]; other site
1081093006878	G-X-G motif; other site
1081093006879	recombination protein RecR; Reviewed; Region: recR; PRK00076
1081093006880	RecR protein; Region: RecR; pfam02132
1081093006881	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1081093006882	putative active site [active]
1081093006883	putative metal-binding site [ion binding]; other site
1081093006884	tetramer interface [polypeptide binding]; other site
1081093006885	hypothetical protein; Validated; Region: PRK00153
1081093006886	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1081093006887	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093006888	Walker A motif; other site
1081093006889	ATP binding site [chemical binding]; other site
1081093006890	Walker B motif; other site
1081093006891	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1081093006892	arginine finger; other site
1081093006893	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1081093006894	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1081093006895	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1081093006896	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1081093006897	active site
1081093006898	hypothetical protein; Provisional; Region: PRK10527
1081093006899	primosomal replication protein N''; Provisional; Region: PRK10093
1081093006900	hypothetical protein; Provisional; Region: PRK11038
1081093006901	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1081093006902	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1081093006903	hypothetical protein; Provisional; Region: PRK11281
1081093006904	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1081093006905	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
1081093006906	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1081093006907	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1081093006908	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093006909	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1081093006910	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1081093006911	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093006912	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1081093006913	Protein export membrane protein; Region: SecD_SecF; cl14618
1081093006914	Protein export membrane protein; Region: SecD_SecF; cl14618
1081093006915	Hha toxicity attenuator; Provisional; Region: PRK10667
1081093006916	gene expression modulator; Provisional; Region: PRK10945
1081093006917	maltose O-acetyltransferase; Provisional; Region: PRK10092
1081093006918	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1081093006919	active site
1081093006920	substrate binding site [chemical binding]; other site
1081093006921	trimer interface [polypeptide binding]; other site
1081093006922	CoA binding site [chemical binding]; other site
1081093006923	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1081093006924	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1081093006925	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1081093006926	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1081093006927	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093006928	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1081093006929	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1081093006930	DNA binding site [nucleotide binding]
1081093006931	active site
1081093006932	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1081093006933	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1081093006934	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1081093006935	active site
1081093006936	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1081093006937	catalytic triad [active]
1081093006938	dimer interface [polypeptide binding]; other site
1081093006939	ammonium transporter; Provisional; Region: PRK10666
1081093006940	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1081093006941	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1081093006942	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1081093006943	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1081093006944	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093006945	Walker A/P-loop; other site
1081093006946	ATP binding site [chemical binding]; other site
1081093006947	Q-loop/lid; other site
1081093006948	ABC transporter signature motif; other site
1081093006949	Walker B; other site
1081093006950	D-loop; other site
1081093006951	H-loop/switch region; other site
1081093006952	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1081093006953	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1081093006954	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093006955	Walker A/P-loop; other site
1081093006956	ATP binding site [chemical binding]; other site
1081093006957	Q-loop/lid; other site
1081093006958	ABC transporter signature motif; other site
1081093006959	Walker B; other site
1081093006960	D-loop; other site
1081093006961	H-loop/switch region; other site
1081093006962	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1081093006963	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1081093006964	putative DNA binding site [nucleotide binding]; other site
1081093006965	putative Zn2+ binding site [ion binding]; other site
1081093006966	AsnC family; Region: AsnC_trans_reg; pfam01037
1081093006967	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1081093006968	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1081093006969	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1081093006970	catalytic residue [active]
1081093006971	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1081093006972	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093006973	active site
1081093006974	motif I; other site
1081093006975	motif II; other site
1081093006976	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1081093006977	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1081093006978	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1081093006979	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1081093006980	Ligand Binding Site [chemical binding]; other site
1081093006981	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1081093006982	active site
1081093006983	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1081093006984	periplasmic folding chaperone; Provisional; Region: PRK10788
1081093006985	SurA N-terminal domain; Region: SurA_N_3; cl07813
1081093006986	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1081093006987	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1081093006988	IHF dimer interface [polypeptide binding]; other site
1081093006989	IHF - DNA interface [nucleotide binding]; other site
1081093006990	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1081093006991	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1081093006992	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1081093006993	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093006994	Walker A motif; other site
1081093006995	ATP binding site [chemical binding]; other site
1081093006996	Walker B motif; other site
1081093006997	arginine finger; other site
1081093006998	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1081093006999	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1081093007000	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1081093007001	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093007002	Walker A motif; other site
1081093007003	ATP binding site [chemical binding]; other site
1081093007004	Walker B motif; other site
1081093007005	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1081093007006	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1081093007007	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1081093007008	oligomer interface [polypeptide binding]; other site
1081093007009	active site residues [active]
1081093007010	trigger factor; Provisional; Region: tig; PRK01490
1081093007011	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1081093007012	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1081093007013	transcriptional regulator BolA; Provisional; Region: PRK11628
1081093007014	hypothetical protein; Provisional; Region: PRK11627
1081093007015	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1081093007016	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1081093007017	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093007018	putative substrate translocation pore; other site
1081093007019	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1081093007020	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1081093007021	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1081093007022	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1081093007023	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1081093007024	D-pathway; other site
1081093007025	Putative ubiquinol binding site [chemical binding]; other site
1081093007026	Low-spin heme (heme b) binding site [chemical binding]; other site
1081093007027	Putative water exit pathway; other site
1081093007028	Binuclear center (heme o3/CuB) [ion binding]; other site
1081093007029	K-pathway; other site
1081093007030	Putative proton exit pathway; other site
1081093007031	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1081093007032	Subunit I/III interface [polypeptide binding]; other site
1081093007033	Subunit III/IV interface [polypeptide binding]; other site
1081093007034	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1081093007035	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1081093007036	UbiA prenyltransferase family; Region: UbiA; pfam01040
1081093007037	Sel1-like repeats; Region: SEL1; smart00671
1081093007038	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1081093007039	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1081093007040	Sel1-like repeats; Region: SEL1; smart00671
1081093007041	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093007042	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1081093007043	putative substrate translocation pore; other site
1081093007044	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1081093007045	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1081093007046	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1081093007047	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1081093007048	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1081093007049	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1081093007050	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1081093007051	conserved cys residue [active]
1081093007052	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
1081093007053	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093007054	motif II; other site
1081093007055	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
1081093007056	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1081093007057	catalytic residue [active]
1081093007058	transcriptional regulator protein; Region: phnR; TIGR03337
1081093007059	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093007060	DNA-binding site [nucleotide binding]; DNA binding site
1081093007061	UTRA domain; Region: UTRA; pfam07702
1081093007062	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
1081093007063	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1081093007064	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
1081093007065	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093007066	Walker A/P-loop; other site
1081093007067	ATP binding site [chemical binding]; other site
1081093007068	Q-loop/lid; other site
1081093007069	ABC transporter signature motif; other site
1081093007070	Walker B; other site
1081093007071	D-loop; other site
1081093007072	H-loop/switch region; other site
1081093007073	TOBE domain; Region: TOBE_2; pfam08402
1081093007074	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
1081093007075	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093007076	dimer interface [polypeptide binding]; other site
1081093007077	conserved gate region; other site
1081093007078	putative PBP binding loops; other site
1081093007079	ABC-ATPase subunit interface; other site
1081093007080	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1081093007081	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093007082	dimer interface [polypeptide binding]; other site
1081093007083	conserved gate region; other site
1081093007084	putative PBP binding loops; other site
1081093007085	ABC-ATPase subunit interface; other site
1081093007086	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1081093007087	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1081093007088	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1081093007089	Ligand Binding Site [chemical binding]; other site
1081093007090	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1081093007091	active site residue [active]
1081093007092	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1081093007093	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1081093007094	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1081093007095	substrate binding pocket [chemical binding]; other site
1081093007096	chain length determination region; other site
1081093007097	substrate-Mg2+ binding site; other site
1081093007098	catalytic residues [active]
1081093007099	aspartate-rich region 1; other site
1081093007100	active site lid residues [active]
1081093007101	aspartate-rich region 2; other site
1081093007102	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1081093007103	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1081093007104	TPP-binding site; other site
1081093007105	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1081093007106	PYR/PP interface [polypeptide binding]; other site
1081093007107	dimer interface [polypeptide binding]; other site
1081093007108	TPP binding site [chemical binding]; other site
1081093007109	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1081093007110	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093007111	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093007112	active site
1081093007113	catalytic tetrad [active]
1081093007114	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1081093007115	tetramer interfaces [polypeptide binding]; other site
1081093007116	binuclear metal-binding site [ion binding]; other site
1081093007117	thiamine monophosphate kinase; Provisional; Region: PRK05731
1081093007118	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1081093007119	ATP binding site [chemical binding]; other site
1081093007120	dimerization interface [polypeptide binding]; other site
1081093007121	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1081093007122	putative RNA binding site [nucleotide binding]; other site
1081093007123	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1081093007124	homopentamer interface [polypeptide binding]; other site
1081093007125	active site
1081093007126	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1081093007127	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1081093007128	catalytic motif [active]
1081093007129	Zn binding site [ion binding]; other site
1081093007130	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1081093007131	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1081093007132	ATP cone domain; Region: ATP-cone; pfam03477
1081093007133	hypothetical protein; Provisional; Region: PRK11530
1081093007134	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1081093007135	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1081093007136	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1081093007137	active site
1081093007138	Predicted transcriptional regulator [Transcription]; Region: COG2378
1081093007139	HTH domain; Region: HTH_11; pfam08279
1081093007140	WYL domain; Region: WYL; pfam13280
1081093007141	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
1081093007142	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1081093007143	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1081093007144	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1081093007145	Protein export membrane protein; Region: SecD_SecF; pfam02355
1081093007146	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1081093007147	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1081093007148	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1081093007149	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1081093007150	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1081093007151	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1081093007152	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1081093007153	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1081093007154	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1081093007155	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1081093007156	peroxidase; Provisional; Region: PRK15000
1081093007157	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1081093007158	dimer interface [polypeptide binding]; other site
1081093007159	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1081093007160	catalytic triad [active]
1081093007161	peroxidatic and resolving cysteines [active]
1081093007162	maltodextrin glucosidase; Provisional; Region: PRK10785
1081093007163	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1081093007164	homodimer interface [polypeptide binding]; other site
1081093007165	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1081093007166	active site
1081093007167	homodimer interface [polypeptide binding]; other site
1081093007168	catalytic site [active]
1081093007169	putative proline-specific permease; Provisional; Region: proY; PRK10580
1081093007170	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1081093007171	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1081093007172	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1081093007173	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1081093007174	putative active site [active]
1081093007175	heme pocket [chemical binding]; other site
1081093007176	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093007177	dimer interface [polypeptide binding]; other site
1081093007178	phosphorylation site [posttranslational modification]
1081093007179	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093007180	ATP binding site [chemical binding]; other site
1081093007181	Mg2+ binding site [ion binding]; other site
1081093007182	G-X-G motif; other site
1081093007183	transcriptional regulator PhoB; Provisional; Region: PRK10161
1081093007184	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093007185	active site
1081093007186	phosphorylation site [posttranslational modification]
1081093007187	intermolecular recognition site; other site
1081093007188	dimerization interface [polypeptide binding]; other site
1081093007189	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093007190	DNA binding site [nucleotide binding]
1081093007191	exonuclease subunit SbcD; Provisional; Region: PRK10966
1081093007192	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1081093007193	active site
1081093007194	metal binding site [ion binding]; metal-binding site
1081093007195	DNA binding site [nucleotide binding]
1081093007196	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1081093007197	exonuclease subunit SbcC; Provisional; Region: PRK10246
1081093007198	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093007199	Walker A/P-loop; other site
1081093007200	ATP binding site [chemical binding]; other site
1081093007201	Q-loop/lid; other site
1081093007202	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093007203	ABC transporter signature motif; other site
1081093007204	Walker B; other site
1081093007205	D-loop; other site
1081093007206	H-loop/switch region; other site
1081093007207	MFS transport protein AraJ; Provisional; Region: PRK10091
1081093007208	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093007209	putative substrate translocation pore; other site
1081093007210	fructokinase; Reviewed; Region: PRK09557
1081093007211	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1081093007212	nucleotide binding site [chemical binding]; other site
1081093007213	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
1081093007214	hypothetical protein; Provisional; Region: PRK10579
1081093007215	hypothetical protein; Provisional; Region: PRK10481
1081093007216	hypothetical protein; Provisional; Region: PRK10380
1081093007217	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1081093007218	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1081093007219	ADP binding site [chemical binding]; other site
1081093007220	magnesium binding site [ion binding]; other site
1081093007221	putative shikimate binding site; other site
1081093007222	Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; cl00727
1081093007223	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1081093007224	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1081093007225	MASE2 domain; Region: MASE2; pfam05230
1081093007226	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1081093007227	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093007228	metal binding site [ion binding]; metal-binding site
1081093007229	active site
1081093007230	I-site; other site
1081093007231	hypothetical protein; Provisional; Region: PRK11505
1081093007232	psiF repeat; Region: PsiF_repeat; pfam07769
1081093007233	psiF repeat; Region: PsiF_repeat; pfam07769
1081093007234	anti-RssB factor; Provisional; Region: PRK10244
1081093007235	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093007236	putative substrate translocation pore; other site
1081093007237	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
1081093007238	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1081093007239	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1081093007240	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1081093007241	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1081093007242	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1081093007243	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1081093007244	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1081093007245	microcin B17 transporter; Reviewed; Region: PRK11098
1081093007246	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1081093007247	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1081093007248	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1081093007249	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1081093007250	ligand binding site [chemical binding]; other site
1081093007251	flexible hinge region; other site
1081093007252	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1081093007253	dimer interface [polypeptide binding]; other site
1081093007254	active site
1081093007255	Schiff base residues; other site
1081093007256	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1081093007257	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1081093007258	acyl-activating enzyme (AAE) consensus motif; other site
1081093007259	AMP binding site [chemical binding]; other site
1081093007260	active site
1081093007261	CoA binding site [chemical binding]; other site
1081093007262	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1081093007263	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1081093007264	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1081093007265	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
1081093007266	dimer interface [polypeptide binding]; other site
1081093007267	active site
1081093007268	citrylCoA binding site [chemical binding]; other site
1081093007269	oxalacetate/citrate binding site [chemical binding]; other site
1081093007270	coenzyme A binding site [chemical binding]; other site
1081093007271	catalytic triad [active]
1081093007272	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1081093007273	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1081093007274	tetramer interface [polypeptide binding]; other site
1081093007275	active site
1081093007276	Mg2+/Mn2+ binding site [ion binding]; other site
1081093007277	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1081093007278	Propionate catabolism activator; Region: PrpR_N; pfam06506
1081093007279	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093007280	Walker A motif; other site
1081093007281	ATP binding site [chemical binding]; other site
1081093007282	Walker B motif; other site
1081093007283	arginine finger; other site
1081093007284	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1081093007285	hypothetical protein; Provisional; Region: PRK09929
1081093007286	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
1081093007287	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1081093007288	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1081093007289	N-terminal plug; other site
1081093007290	ligand-binding site [chemical binding]; other site
1081093007291	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1081093007292	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1081093007293	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1081093007294	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1081093007295	putative sialic acid transporter; Region: 2A0112; TIGR00891
1081093007296	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093007297	putative substrate translocation pore; other site
1081093007298	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1081093007299	metal-binding site [ion binding]
1081093007300	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
1081093007301	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1081093007302	DNA binding residues [nucleotide binding]
1081093007303	dimer interface [polypeptide binding]; other site
1081093007304	copper binding site [ion binding]; other site
1081093007305	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1081093007306	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1081093007307	metal-binding site [ion binding]
1081093007308	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1081093007309	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093007310	motif II; other site
1081093007311	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1081093007312	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1081093007313	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093007314	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1081093007315	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1081093007316	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1081093007317	DNA binding residues [nucleotide binding]
1081093007318	dimerization interface [polypeptide binding]; other site
1081093007319	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1081093007320	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1081093007321	DNA binding site [nucleotide binding]
1081093007322	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1081093007323	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093007324	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1081093007325	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093007326	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093007327	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
1081093007328	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
1081093007329	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093007330	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093007331	transcriptional activator TtdR; Provisional; Region: PRK09801
1081093007332	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093007333	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
1081093007334	putative effector binding pocket; other site
1081093007335	putative dimerization interface [polypeptide binding]; other site
1081093007336	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1081093007337	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1081093007338	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1081093007339	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1081093007340	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1081093007341	substrate binding site [chemical binding]; other site
1081093007342	ligand binding site [chemical binding]; other site
1081093007343	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1081093007344	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093007345	putative substrate translocation pore; other site
1081093007346	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
1081093007347	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1081093007348	Transposase; Region: HTH_Tnp_1; cl17663
1081093007349	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1081093007350	HTH-like domain; Region: HTH_21; pfam13276
1081093007351	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1081093007352	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1081093007353	putative catalytic cysteine [active]
1081093007354	gamma-glutamyl kinase; Provisional; Region: PRK05429
1081093007355	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1081093007356	nucleotide binding site [chemical binding]; other site
1081093007357	homotetrameric interface [polypeptide binding]; other site
1081093007358	putative phosphate binding site [ion binding]; other site
1081093007359	putative allosteric binding site; other site
1081093007360	PUA domain; Region: PUA; pfam01472
1081093007361	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1081093007362	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1081093007363	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1081093007364	active site
1081093007365	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1081093007366	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1081093007367	metal binding site [ion binding]; metal-binding site
1081093007368	dimer interface [polypeptide binding]; other site
1081093007369	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1081093007370	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1081093007371	hypothetical protein; Reviewed; Region: PRK09588
1081093007372	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
1081093007373	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1081093007374	active site
1081093007375	DNA polymerase IV; Validated; Region: PRK02406
1081093007376	DNA binding site [nucleotide binding]
1081093007377	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1081093007378	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1081093007379	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1081093007380	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1081093007381	putative active site [active]
1081093007382	putative dimer interface [polypeptide binding]; other site
1081093007383	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1081093007384	dimer interface [polypeptide binding]; other site
1081093007385	active site
1081093007386	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1081093007387	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1081093007388	active site
1081093007389	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1081093007390	C-N hydrolase family amidase; Provisional; Region: PRK10438
1081093007391	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1081093007392	putative active site [active]
1081093007393	catalytic triad [active]
1081093007394	dimer interface [polypeptide binding]; other site
1081093007395	multimer interface [polypeptide binding]; other site
1081093007396	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1081093007397	dimer interface [polypeptide binding]; other site
1081093007398	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1081093007399	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093007400	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093007401	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093007402	dimerization interface [polypeptide binding]; other site
1081093007403	PerC transcriptional activator; Region: PerC; pfam06069
1081093007404	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1081093007405	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
1081093007406	putative active site [active]
1081093007407	putative metal binding site [ion binding]; other site
1081093007408	putative pilin structural protein SafD; Provisional; Region: PRK15222
1081093007409	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
1081093007410	PapC N-terminal domain; Region: PapC_N; pfam13954
1081093007411	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1081093007412	PapC C-terminal domain; Region: PapC_C; pfam13953
1081093007413	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
1081093007414	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093007415	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093007416	Saf-pilin pilus formation protein; Region: Saf-Nte_pilin; cl09697
1081093007417	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1081093007418	Integrase core domain; Region: rve_3; pfam13683
1081093007419	potential frameshift: common BLAST hit: gi|198243880|ref|YP_002214226.1| ATPase
1081093007420	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093007421	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1081093007422	Walker A motif; other site
1081093007423	ATP binding site [chemical binding]; other site
1081093007424	Walker B motif; other site
1081093007425	arginine finger; other site
1081093007426	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1081093007427	RHS protein; Region: RHS; pfam03527
1081093007428	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1081093007429	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
1081093007430	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
1081093007431	potential frameshift: common BLAST hit: gi|302877918|ref|YP_003846482.1| NERD domain-containing protein
1081093007432	Part of AAA domain; Region: AAA_19; pfam13245
1081093007433	AAA domain; Region: AAA_30; pfam13604
1081093007434	AAA domain; Region: AAA_12; pfam13087
1081093007435	Nuclease-related domain; Region: NERD; pfam08378
1081093007436	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
1081093007437	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1081093007438	active site
1081093007439	ATP binding site [chemical binding]; other site
1081093007440	Predicted GTPase [General function prediction only]; Region: COG3596
1081093007441	YfjP GTPase; Region: YfjP; cd11383
1081093007442	G1 box; other site
1081093007443	GTP/Mg2+ binding site [chemical binding]; other site
1081093007444	Switch I region; other site
1081093007445	G2 box; other site
1081093007446	Switch II region; other site
1081093007447	G3 box; other site
1081093007448	G4 box; other site
1081093007449	G5 box; other site
1081093007450	Stage III sporulation protein D; Region: SpoIIID; cl17560
1081093007451	WYL domain; Region: WYL; cl14852
1081093007452	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
1081093007453	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
1081093007454	Domain of unknown function (DUF932); Region: DUF932; pfam06067
1081093007455	Antirestriction protein; Region: Antirestrict; pfam03230
1081093007456	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1081093007457	MPN+ (JAMM) motif; other site
1081093007458	Zinc-binding site [ion binding]; other site
1081093007459	Protein of unknown function (DUF987); Region: DUF987; pfam06174
1081093007460	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1081093007461	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1081093007462	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1081093007463	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate...; Region: PLPDE_IV; cl00224
1081093007464	catalytic residue [active]
1081093007465	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
1081093007466	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1081093007467	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1081093007468	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1081093007469	active site
1081093007470	catalytic site [active]
1081093007471	substrate binding site [chemical binding]; other site
1081093007472	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1081093007473	RNA/DNA hybrid binding site [nucleotide binding]; other site
1081093007474	active site
1081093007475	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1081093007476	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093007477	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1081093007478	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1081093007479	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1081093007480	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1081093007481	catalytic residue [active]
1081093007482	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1081093007483	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1081093007484	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1081093007485	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1081093007486	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1081093007487	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093007488	S-adenosylmethionine binding site [chemical binding]; other site
1081093007489	hypothetical protein; Provisional; Region: PRK05421
1081093007490	putative catalytic site [active]
1081093007491	putative metal binding site [ion binding]; other site
1081093007492	putative phosphate binding site [ion binding]; other site
1081093007493	putative catalytic site [active]
1081093007494	putative phosphate binding site [ion binding]; other site
1081093007495	putative metal binding site [ion binding]; other site
1081093007496	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1081093007497	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093007498	putative substrate translocation pore; other site
1081093007499	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093007500	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093007501	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1081093007502	putative effector binding pocket; other site
1081093007503	dimerization interface [polypeptide binding]; other site
1081093007504	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093007505	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093007506	active site
1081093007507	catalytic tetrad [active]
1081093007508	protein disaggregation chaperone; Provisional; Region: PRK10865
1081093007509	Clp amino terminal domain; Region: Clp_N; pfam02861
1081093007510	Clp amino terminal domain; Region: Clp_N; pfam02861
1081093007511	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093007512	Walker A motif; other site
1081093007513	ATP binding site [chemical binding]; other site
1081093007514	Walker B motif; other site
1081093007515	arginine finger; other site
1081093007516	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093007517	Walker A motif; other site
1081093007518	ATP binding site [chemical binding]; other site
1081093007519	Walker B motif; other site
1081093007520	arginine finger; other site
1081093007521	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1081093007522	hypothetical protein; Provisional; Region: PRK10723
1081093007523	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1081093007524	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1081093007525	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1081093007526	RNA binding surface [nucleotide binding]; other site
1081093007527	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1081093007528	active site
1081093007529	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1081093007530	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1081093007531	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1081093007532	30S subunit binding site; other site
1081093007533	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1081093007534	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1081093007535	Prephenate dehydratase; Region: PDT; pfam00800
1081093007536	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1081093007537	putative L-Phe binding site [chemical binding]; other site
1081093007538	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1081093007539	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1081093007540	Chorismate mutase type II; Region: CM_2; cl00693
1081093007541	prephenate dehydrogenase; Validated; Region: PRK08507
1081093007542	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1081093007543	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1081093007544	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1081093007545	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1081093007546	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093007547	metal binding site [ion binding]; metal-binding site
1081093007548	active site
1081093007549	I-site; other site
1081093007550	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1081093007551	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1081093007552	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1081093007553	RimM N-terminal domain; Region: RimM; pfam01782
1081093007554	PRC-barrel domain; Region: PRC; pfam05239
1081093007555	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1081093007556	signal recognition particle protein; Provisional; Region: PRK10867
1081093007557	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1081093007558	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1081093007559	P loop; other site
1081093007560	GTP binding site [chemical binding]; other site
1081093007561	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1081093007562	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1081093007563	hypothetical protein; Provisional; Region: PRK11573
1081093007564	Domain of unknown function DUF21; Region: DUF21; pfam01595
1081093007565	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1081093007566	Transporter associated domain; Region: CorC_HlyC; smart01091
1081093007567	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1081093007568	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1081093007569	dimer interface [polypeptide binding]; other site
1081093007570	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1081093007571	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1081093007572	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1081093007573	recombination and repair protein; Provisional; Region: PRK10869
1081093007574	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1081093007575	Walker A/P-loop; other site
1081093007576	ATP binding site [chemical binding]; other site
1081093007577	Q-loop/lid; other site
1081093007578	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1081093007579	ABC transporter signature motif; other site
1081093007580	Walker B; other site
1081093007581	D-loop; other site
1081093007582	H-loop/switch region; other site
1081093007583	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1081093007584	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1081093007585	hypothetical protein; Validated; Region: PRK01777
1081093007586	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1081093007587	putative coenzyme Q binding site [chemical binding]; other site
1081093007588	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1081093007589	SmpB-tmRNA interface; other site
1081093007590	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1081093007591	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1081093007592	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1081093007593	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093007594	Walker A/P-loop; other site
1081093007595	ATP binding site [chemical binding]; other site
1081093007596	Q-loop/lid; other site
1081093007597	ABC transporter signature motif; other site
1081093007598	Walker B; other site
1081093007599	D-loop; other site
1081093007600	H-loop/switch region; other site
1081093007601	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1081093007602	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093007603	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1081093007604	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1081093007605	Integrase core domain; Region: rve; pfam00665
1081093007606	Integrase core domain; Region: rve_3; pfam13683
1081093007607	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1081093007608	DNA-binding interface [nucleotide binding]; DNA binding site
1081093007609	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
1081093007610	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1081093007611	homodimer interface [polypeptide binding]; other site
1081093007612	active site
1081093007613	TDP-binding site; other site
1081093007614	acceptor substrate-binding pocket; other site
1081093007615	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1081093007616	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093007617	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1081093007618	Walker A/P-loop; other site
1081093007619	ATP binding site [chemical binding]; other site
1081093007620	Q-loop/lid; other site
1081093007621	ABC transporter signature motif; other site
1081093007622	Walker B; other site
1081093007623	D-loop; other site
1081093007624	H-loop/switch region; other site
1081093007625	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1081093007626	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1081093007627	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093007628	Walker A/P-loop; other site
1081093007629	ATP binding site [chemical binding]; other site
1081093007630	Q-loop/lid; other site
1081093007631	ABC transporter signature motif; other site
1081093007632	Walker B; other site
1081093007633	D-loop; other site
1081093007634	H-loop/switch region; other site
1081093007635	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1081093007636	outer membrane receptor FepA; Provisional; Region: PRK13528
1081093007637	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1081093007638	N-terminal plug; other site
1081093007639	ligand-binding site [chemical binding]; other site
1081093007640	secreted effector protein PipB2; Provisional; Region: PRK15196
1081093007641	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1081093007642	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1081093007643	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1081093007644	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1081093007645	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1081093007646	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
1081093007647	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
1081093007648	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1081093007649	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1081093007650	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
1081093007651	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1081093007652	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1081093007653	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093007654	dimer interface [polypeptide binding]; other site
1081093007655	phosphorylation site [posttranslational modification]
1081093007656	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093007657	ATP binding site [chemical binding]; other site
1081093007658	Mg2+ binding site [ion binding]; other site
1081093007659	G-X-G motif; other site
1081093007660	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093007661	active site
1081093007662	phosphorylation site [posttranslational modification]
1081093007663	intermolecular recognition site; other site
1081093007664	dimerization interface [polypeptide binding]; other site
1081093007665	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093007666	DNA binding site [nucleotide binding]
1081093007667	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1081093007668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1081093007669	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
1081093007670	substrate binding pocket [chemical binding]; other site
1081093007671	active site
1081093007672	iron coordination sites [ion binding]; other site
1081093007673	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
1081093007674	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1081093007675	tetramerization interface [polypeptide binding]; other site
1081093007676	NAD(P) binding site [chemical binding]; other site
1081093007677	catalytic residues [active]
1081093007678	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
1081093007679	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
1081093007680	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093007681	DNA-binding site [nucleotide binding]; DNA binding site
1081093007682	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1081093007683	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1081093007684	bacterial OsmY and nodulation domain; Region: BON; smart00749
1081093007685	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1081093007686	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1081093007687	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1081093007688	dimerization interface [polypeptide binding]; other site
1081093007689	putative DNA binding site [nucleotide binding]; other site
1081093007690	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1081093007691	putative Zn2+ binding site [ion binding]; other site
1081093007692	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1081093007693	active site residue [active]
1081093007694	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1081093007695	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1081093007696	hypothetical protein; Provisional; Region: PRK10556
1081093007697	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1081093007698	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1081093007699	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1081093007700	catalytic residues [active]
1081093007701	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1081093007702	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1081093007703	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1081093007704	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1081093007705	active site
1081093007706	dimer interface [polypeptide binding]; other site
1081093007707	catalytic residues [active]
1081093007708	effector binding site; other site
1081093007709	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1081093007710	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1081093007711	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1081093007712	dimer interface [polypeptide binding]; other site
1081093007713	putative radical transfer pathway; other site
1081093007714	diiron center [ion binding]; other site
1081093007715	tyrosyl radical; other site
1081093007716	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1081093007717	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1081093007718	Walker A/P-loop; other site
1081093007719	ATP binding site [chemical binding]; other site
1081093007720	Q-loop/lid; other site
1081093007721	ABC transporter signature motif; other site
1081093007722	Walker B; other site
1081093007723	D-loop; other site
1081093007724	H-loop/switch region; other site
1081093007725	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1081093007726	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1081093007727	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1081093007728	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1081093007729	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093007730	transcriptional repressor MprA; Provisional; Region: PRK10870
1081093007731	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1081093007732	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1081093007733	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1081093007734	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093007735	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1081093007736	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1081093007737	glutamate--cysteine ligase; Provisional; Region: PRK02107
1081093007738	Predicted membrane protein [Function unknown]; Region: COG1238
1081093007739	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1081093007740	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093007741	motif II; other site
1081093007742	carbon storage regulator; Provisional; Region: PRK01712
1081093007743	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1081093007744	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1081093007745	motif 1; other site
1081093007746	active site
1081093007747	motif 2; other site
1081093007748	motif 3; other site
1081093007749	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1081093007750	DHHA1 domain; Region: DHHA1; pfam02272
1081093007751	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1081093007752	recombinase A; Provisional; Region: recA; PRK09354
1081093007753	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1081093007754	hexamer interface [polypeptide binding]; other site
1081093007755	Walker A motif; other site
1081093007756	ATP binding site [chemical binding]; other site
1081093007757	Walker B motif; other site
1081093007758	hypothetical protein; Validated; Region: PRK03661
1081093007759	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1081093007760	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1081093007761	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1081093007762	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1081093007763	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1081093007764	Nucleoside recognition; Region: Gate; pfam07670
1081093007765	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1081093007766	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1081093007767	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1081093007768	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1081093007769	putative NAD(P) binding site [chemical binding]; other site
1081093007770	active site
1081093007771	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1081093007772	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1081093007773	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1081093007774	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093007775	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1081093007776	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1081093007777	putative active site [active]
1081093007778	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1081093007779	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1081093007780	GAF domain; Region: GAF; pfam01590
1081093007781	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093007782	Walker A motif; other site
1081093007783	ATP binding site [chemical binding]; other site
1081093007784	Walker B motif; other site
1081093007785	arginine finger; other site
1081093007786	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1081093007787	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1081093007788	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1081093007789	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1081093007790	iron binding site [ion binding]; other site
1081093007791	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1081093007792	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093007793	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1081093007794	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1081093007795	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1081093007796	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1081093007797	nickel binding site [ion binding]; other site
1081093007798	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1081093007799	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1081093007800	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1081093007801	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1081093007802	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1081093007803	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1081093007804	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1081093007805	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1081093007806	NADH dehydrogenase; Region: NADHdh; cl00469
1081093007807	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1081093007808	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1081093007809	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1081093007810	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1081093007811	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1081093007812	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1081093007813	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1081093007814	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1081093007815	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1081093007816	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1081093007817	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1081093007818	dimerization interface [polypeptide binding]; other site
1081093007819	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1081093007820	ATP binding site [chemical binding]; other site
1081093007821	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1081093007822	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1081093007823	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1081093007824	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093007825	Walker A motif; other site
1081093007826	ATP binding site [chemical binding]; other site
1081093007827	Walker B motif; other site
1081093007828	arginine finger; other site
1081093007829	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1081093007830	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1081093007831	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1081093007832	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1081093007833	metal binding site [ion binding]; metal-binding site
1081093007834	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1081093007835	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1081093007836	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1081093007837	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1081093007838	ABC-ATPase subunit  interface; other site
1081093007839	dimer interface [polypeptide binding]; other site
1081093007840	putative PBP binding regions; other site
1081093007841	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1081093007842	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1081093007843	ABC-ATPase subunit  interface; other site
1081093007844	dimer interface [polypeptide binding]; other site
1081093007845	putative PBP binding regions; other site
1081093007846	effector protein YopJ; Provisional; Region: PRK15371
1081093007847	transcriptional activator SprB; Provisional; Region: PRK15320
1081093007848	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1081093007849	transcriptional regulator SirC; Provisional; Region: PRK15044
1081093007850	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093007851	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
1081093007852	invasion protein OrgB; Provisional; Region: PRK15322
1081093007853	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
1081093007854	invasion protein OrgA; Provisional; Region: PRK15323
1081093007855	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
1081093007856	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1081093007857	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
1081093007858	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
1081093007859	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1081093007860	transcriptional regulator HilD; Provisional; Region: PRK15185
1081093007861	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093007862	invasion protein regulator; Provisional; Region: PRK12370
1081093007863	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093007864	DNA binding site [nucleotide binding]
1081093007865	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1081093007866	binding surface
1081093007867	TPR motif; other site
1081093007868	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1081093007869	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1081093007870	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1081093007871	catalytic residue [active]
1081093007872	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
1081093007873	SicP binding; Region: SicP-binding; pfam09119
1081093007874	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
1081093007875	switch II binding region; other site
1081093007876	Rac1 P-loop interaction site [polypeptide binding]; other site
1081093007877	GTP binding residues [chemical binding]; other site
1081093007878	switch I binding region; other site
1081093007879	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
1081093007880	active site
1081093007881	chaperone protein SicP; Provisional; Region: PRK15329
1081093007882	putative acyl carrier protein IacP; Validated; Region: PRK08172
1081093007883	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
1081093007884	cell invasion protein SipD; Provisional; Region: PRK15330
1081093007885	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
1081093007886	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
1081093007887	chaperone protein SicA; Provisional; Region: PRK15331
1081093007888	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1081093007889	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1081093007890	type III secretion system protein SpaS; Validated; Region: PRK08156
1081093007891	type III secretion system protein SpaR; Provisional; Region: PRK15332
1081093007892	type III secretion system protein SpaQ; Provisional; Region: PRK15333
1081093007893	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1081093007894	type III secretion system protein SpaO; Validated; Region: PRK08158
1081093007895	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1081093007896	antigen presentation protein SpaN; Provisional; Region: PRK15334
1081093007897	Surface presentation of antigens protein; Region: SPAN; pfam02510
1081093007898	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; cl03442
1081093007899	ATP synthase SpaL; Validated; Region: PRK08149
1081093007900	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1081093007901	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1081093007902	Walker A motif; other site
1081093007903	ATP binding site [chemical binding]; other site
1081093007904	Walker B motif; other site
1081093007905	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
1081093007906	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
1081093007907	type III secretion system protein InvA; Provisional; Region: PRK15337
1081093007908	type III secretion system regulator InvE; Provisional; Region: PRK15338
1081093007909	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
1081093007910	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
1081093007911	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1081093007912	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1081093007913	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1081093007914	transcriptional regulator InvF; Provisional; Region: PRK15340
1081093007915	InvH outer membrane lipoprotein; Region: InvH; pfam04741
1081093007916	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1081093007917	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1081093007918	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1081093007919	active site
1081093007920	metal binding site [ion binding]; metal-binding site
1081093007921	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1081093007922	MutS domain I; Region: MutS_I; pfam01624
1081093007923	MutS domain II; Region: MutS_II; pfam05188
1081093007924	MutS domain III; Region: MutS_III; pfam05192
1081093007925	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1081093007926	Walker A/P-loop; other site
1081093007927	ATP binding site [chemical binding]; other site
1081093007928	Q-loop/lid; other site
1081093007929	ABC transporter signature motif; other site
1081093007930	Walker B; other site
1081093007931	D-loop; other site
1081093007932	H-loop/switch region; other site
1081093007933	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1081093007934	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093007935	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1081093007936	putative substrate translocation pore; other site
1081093007937	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093007938	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093007939	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1081093007940	putative effector binding pocket; other site
1081093007941	dimerization interface [polypeptide binding]; other site
1081093007942	GntP family permease; Region: GntP_permease; pfam02447
1081093007943	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1081093007944	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1081093007945	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
1081093007946	putative NAD(P) binding site [chemical binding]; other site
1081093007947	active site
1081093007948	putative substrate binding site [chemical binding]; other site
1081093007949	hypothetical protein; Provisional; Region: PRK09989
1081093007950	putative aldolase; Validated; Region: PRK08130
1081093007951	intersubunit interface [polypeptide binding]; other site
1081093007952	active site
1081093007953	Zn2+ binding site [ion binding]; other site
1081093007954	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1081093007955	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1081093007956	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1081093007957	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093007958	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1081093007959	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093007960	MarR family; Region: MarR_2; cl17246
1081093007961	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1081093007962	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1081093007963	Flavoprotein; Region: Flavoprotein; pfam02441
1081093007964	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1081093007965	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1081093007966	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1081093007967	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1081093007968	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1081093007969	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1081093007970	DNA binding residues [nucleotide binding]
1081093007971	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
1081093007972	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1081093007973	Peptidase family M23; Region: Peptidase_M23; pfam01551
1081093007974	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1081093007975	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093007976	S-adenosylmethionine binding site [chemical binding]; other site
1081093007977	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1081093007978	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1081093007979	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1081093007980	Permutation of conserved domain; other site
1081093007981	active site
1081093007982	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1081093007983	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1081093007984	homotrimer interaction site [polypeptide binding]; other site
1081093007985	zinc binding site [ion binding]; other site
1081093007986	CDP-binding sites; other site
1081093007987	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1081093007988	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1081093007989	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1081093007990	ligand-binding site [chemical binding]; other site
1081093007991	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1081093007992	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1081093007993	CysD dimerization site [polypeptide binding]; other site
1081093007994	G1 box; other site
1081093007995	putative GEF interaction site [polypeptide binding]; other site
1081093007996	GTP/Mg2+ binding site [chemical binding]; other site
1081093007997	Switch I region; other site
1081093007998	G2 box; other site
1081093007999	G3 box; other site
1081093008000	Switch II region; other site
1081093008001	G4 box; other site
1081093008002	G5 box; other site
1081093008003	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1081093008004	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1081093008005	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1081093008006	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1081093008007	Active Sites [active]
1081093008008	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1081093008009	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1081093008010	metal binding site [ion binding]; metal-binding site
1081093008011	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
1081093008012	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
1081093008013	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1081093008014	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
1081093008015	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
1081093008016	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09731
1081093008017	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
1081093008018	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1081093008019	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
1081093008020	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1081093008021	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
1081093008022	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1081093008023	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1081093008024	Active Sites [active]
1081093008025	sulfite reductase subunit beta; Provisional; Region: PRK13504
1081093008026	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1081093008027	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1081093008028	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1081093008029	Flavodoxin; Region: Flavodoxin_1; pfam00258
1081093008030	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1081093008031	FAD binding pocket [chemical binding]; other site
1081093008032	FAD binding motif [chemical binding]; other site
1081093008033	catalytic residues [active]
1081093008034	NAD binding pocket [chemical binding]; other site
1081093008035	phosphate binding motif [ion binding]; other site
1081093008036	beta-alpha-beta structure motif; other site
1081093008037	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1081093008038	active site
1081093008039	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
1081093008040	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1081093008041	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1081093008042	enolase; Provisional; Region: eno; PRK00077
1081093008043	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1081093008044	dimer interface [polypeptide binding]; other site
1081093008045	metal binding site [ion binding]; metal-binding site
1081093008046	substrate binding pocket [chemical binding]; other site
1081093008047	CTP synthetase; Validated; Region: pyrG; PRK05380
1081093008048	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1081093008049	Catalytic site [active]
1081093008050	active site
1081093008051	UTP binding site [chemical binding]; other site
1081093008052	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1081093008053	active site
1081093008054	putative oxyanion hole; other site
1081093008055	catalytic triad [active]
1081093008056	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1081093008057	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1081093008058	homodimer interface [polypeptide binding]; other site
1081093008059	metal binding site [ion binding]; metal-binding site
1081093008060	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1081093008061	homodimer interface [polypeptide binding]; other site
1081093008062	active site
1081093008063	putative chemical substrate binding site [chemical binding]; other site
1081093008064	metal binding site [ion binding]; metal-binding site
1081093008065	fimbrial protein SteA; Provisional; Region: PRK15261
1081093008066	putative fimbrial outer membrane usher protein SteB; Provisional; Region: PRK15273
1081093008067	PapC N-terminal domain; Region: PapC_N; pfam13954
1081093008068	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1081093008069	PapC C-terminal domain; Region: PapC_C; pfam13953
1081093008070	putative periplasmic fimbrial chaperone protein SteC; Provisional; Region: PRK15274
1081093008071	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093008072	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093008073	putative fimbrial protein SteD; Provisional; Region: PRK15275
1081093008074	putative fimbrial subunit SteE; Provisional; Region: PRK15276
1081093008075	fimbrial protein SteF; Provisional; Region: PRK15260
1081093008076	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1081093008077	HD domain; Region: HD_4; pfam13328
1081093008078	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1081093008079	synthetase active site [active]
1081093008080	NTP binding site [chemical binding]; other site
1081093008081	metal binding site [ion binding]; metal-binding site
1081093008082	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1081093008083	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1081093008084	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1081093008085	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1081093008086	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1081093008087	active site
1081093008088	tetramer interface [polypeptide binding]; other site
1081093008089	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093008090	D-galactonate transporter; Region: 2A0114; TIGR00893
1081093008091	putative substrate translocation pore; other site
1081093008092	flavodoxin; Provisional; Region: PRK08105
1081093008093	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1081093008094	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1081093008095	probable active site [active]
1081093008096	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1081093008097	SecY interacting protein Syd; Provisional; Region: PRK04968
1081093008098	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1081093008099	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1081093008100	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1081093008101	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1081093008102	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1081093008103	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1081093008104	serine transporter; Region: stp; TIGR00814
1081093008105	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1081093008106	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1081093008107	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1081093008108	flap endonuclease-like protein; Provisional; Region: PRK09482
1081093008109	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1081093008110	active site
1081093008111	metal binding site 1 [ion binding]; metal-binding site
1081093008112	putative 5' ssDNA interaction site; other site
1081093008113	metal binding site 3; metal-binding site
1081093008114	metal binding site 2 [ion binding]; metal-binding site
1081093008115	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1081093008116	putative DNA binding site [nucleotide binding]; other site
1081093008117	putative metal binding site [ion binding]; other site
1081093008118	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1081093008119	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1081093008120	dimer interface [polypeptide binding]; other site
1081093008121	active site
1081093008122	metal binding site [ion binding]; metal-binding site
1081093008123	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1081093008124	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1081093008125	intersubunit interface [polypeptide binding]; other site
1081093008126	active site
1081093008127	Zn2+ binding site [ion binding]; other site
1081093008128	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1081093008129	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093008130	putative substrate translocation pore; other site
1081093008131	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1081093008132	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
1081093008133	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1081093008134	trimer interface [polypeptide binding]; other site
1081093008135	substrate binding site [chemical binding]; other site
1081093008136	Mn binding site [ion binding]; other site
1081093008137	L-fuculokinase; Provisional; Region: PRK10331
1081093008138	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1081093008139	nucleotide binding site [chemical binding]; other site
1081093008140	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1081093008141	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1081093008142	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1081093008143	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093008144	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1081093008145	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1081093008146	hypothetical protein; Provisional; Region: PRK10873
1081093008147	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1081093008148	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093008149	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1081093008150	dimerization interface [polypeptide binding]; other site
1081093008151	substrate binding pocket [chemical binding]; other site
1081093008152	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1081093008153	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1081093008154	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1081093008155	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1081093008156	catalytic residue [active]
1081093008157	CsdA-binding activator; Provisional; Region: PRK15019
1081093008158	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1081093008159	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1081093008160	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1081093008161	putative ATP binding site [chemical binding]; other site
1081093008162	putative substrate interface [chemical binding]; other site
1081093008163	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1081093008164	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1081093008165	MltA specific insert domain; Region: MltA; pfam03562
1081093008166	3D domain; Region: 3D; pfam06725
1081093008167	AMIN domain; Region: AMIN; pfam11741
1081093008168	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1081093008169	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1081093008170	active site
1081093008171	metal binding site [ion binding]; metal-binding site
1081093008172	N-acetylglutamate synthase; Validated; Region: PRK05279
1081093008173	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1081093008174	putative feedback inhibition sensing region; other site
1081093008175	putative nucleotide binding site [chemical binding]; other site
1081093008176	putative substrate binding site [chemical binding]; other site
1081093008177	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093008178	Coenzyme A binding pocket [chemical binding]; other site
1081093008179	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1081093008180	AAA domain; Region: AAA_30; pfam13604
1081093008181	Family description; Region: UvrD_C_2; pfam13538
1081093008182	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1081093008183	protease3; Provisional; Region: PRK15101
1081093008184	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1081093008185	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1081093008186	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1081093008187	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1081093008188	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1081093008189	hypothetical protein; Provisional; Region: PRK10332
1081093008190	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1081093008191	hypothetical protein; Provisional; Region: PRK11521
1081093008192	hypothetical protein; Provisional; Region: PRK10557
1081093008193	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1081093008194	hypothetical protein; Provisional; Region: PRK10506
1081093008195	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1081093008196	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1081093008197	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1081093008198	dimerization interface [polypeptide binding]; other site
1081093008199	active site
1081093008200	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1081093008201	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1081093008202	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1081093008203	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1081093008204	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1081093008205	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1081093008206	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1081093008207	putative active site [active]
1081093008208	Ap4A binding site [chemical binding]; other site
1081093008209	nudix motif; other site
1081093008210	putative metal binding site [ion binding]; other site
1081093008211	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1081093008212	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1081093008213	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093008214	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093008215	active site
1081093008216	catalytic tetrad [active]
1081093008217	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1081093008218	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093008219	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1081093008220	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1081093008221	putative acyl-acceptor binding pocket; other site
1081093008222	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1081093008223	acyl-activating enzyme (AAE) consensus motif; other site
1081093008224	putative AMP binding site [chemical binding]; other site
1081093008225	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1081093008226	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093008227	DNA binding site [nucleotide binding]
1081093008228	domain linker motif; other site
1081093008229	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1081093008230	dimerization interface (closed form) [polypeptide binding]; other site
1081093008231	ligand binding site [chemical binding]; other site
1081093008232	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1081093008233	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093008234	DNA binding site [nucleotide binding]
1081093008235	domain linker motif; other site
1081093008236	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1081093008237	dimerization interface (closed form) [polypeptide binding]; other site
1081093008238	ligand binding site [chemical binding]; other site
1081093008239	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1081093008240	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1081093008241	active site
1081093008242	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1081093008243	substrate binding site [chemical binding]; other site
1081093008244	catalytic residues [active]
1081093008245	dimer interface [polypeptide binding]; other site
1081093008246	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1081093008247	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093008248	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093008249	dimerization interface [polypeptide binding]; other site
1081093008250	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1081093008251	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093008252	putative substrate translocation pore; other site
1081093008253	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093008254	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1081093008255	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1081093008256	NADP binding site [chemical binding]; other site
1081093008257	homodimer interface [polypeptide binding]; other site
1081093008258	active site
1081093008259	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1081093008260	putative acyltransferase; Provisional; Region: PRK05790
1081093008261	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1081093008262	dimer interface [polypeptide binding]; other site
1081093008263	active site
1081093008264	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093008265	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093008266	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1081093008267	dimerization interface [polypeptide binding]; other site
1081093008268	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
1081093008269	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1081093008270	Peptidase family M23; Region: Peptidase_M23; pfam01551
1081093008271	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1081093008272	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1081093008273	active site
1081093008274	metal binding site [ion binding]; metal-binding site
1081093008275	nudix motif; other site
1081093008276	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1081093008277	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1081093008278	dimer interface [polypeptide binding]; other site
1081093008279	putative anticodon binding site; other site
1081093008280	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1081093008281	motif 1; other site
1081093008282	active site
1081093008283	motif 2; other site
1081093008284	motif 3; other site
1081093008285	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1081093008286	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1081093008287	RF-1 domain; Region: RF-1; pfam00472
1081093008288	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1081093008289	DHH family; Region: DHH; pfam01368
1081093008290	DHHA1 domain; Region: DHHA1; pfam02272
1081093008291	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1081093008292	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1081093008293	dimerization domain [polypeptide binding]; other site
1081093008294	dimer interface [polypeptide binding]; other site
1081093008295	catalytic residues [active]
1081093008296	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1081093008297	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1081093008298	active site
1081093008299	Int/Topo IB signature motif; other site
1081093008300	flavodoxin FldB; Provisional; Region: PRK12359
1081093008301	hypothetical protein; Provisional; Region: PRK10878
1081093008302	putative global regulator; Reviewed; Region: PRK09559
1081093008303	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1081093008304	hemolysin; Provisional; Region: PRK15087
1081093008305	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1081093008306	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1081093008307	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1081093008308	beta-galactosidase; Region: BGL; TIGR03356
1081093008309	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
1081093008310	glycine dehydrogenase; Provisional; Region: PRK05367
1081093008311	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1081093008312	tetramer interface [polypeptide binding]; other site
1081093008313	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093008314	catalytic residue [active]
1081093008315	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1081093008316	tetramer interface [polypeptide binding]; other site
1081093008317	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093008318	catalytic residue [active]
1081093008319	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1081093008320	lipoyl attachment site [posttranslational modification]; other site
1081093008321	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1081093008322	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1081093008323	oxidoreductase; Provisional; Region: PRK08013
1081093008324	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1081093008325	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1081093008326	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1081093008327	proline aminopeptidase P II; Provisional; Region: PRK10879
1081093008328	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1081093008329	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1081093008330	active site
1081093008331	hypothetical protein; Reviewed; Region: PRK01736
1081093008332	Z-ring-associated protein; Provisional; Region: PRK10972
1081093008333	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1081093008334	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1081093008335	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1081093008336	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1081093008337	ligand binding site [chemical binding]; other site
1081093008338	NAD binding site [chemical binding]; other site
1081093008339	tetramer interface [polypeptide binding]; other site
1081093008340	catalytic site [active]
1081093008341	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1081093008342	L-serine binding site [chemical binding]; other site
1081093008343	ACT domain interface; other site
1081093008344	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1081093008345	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1081093008346	active site
1081093008347	dimer interface [polypeptide binding]; other site
1081093008348	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1081093008349	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093008350	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1081093008351	putative dimerization interface [polypeptide binding]; other site
1081093008352	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1081093008353	oxidative stress defense protein; Provisional; Region: PRK11087
1081093008354	arginine exporter protein; Provisional; Region: PRK09304
1081093008355	mechanosensitive channel MscS; Provisional; Region: PRK10334
1081093008356	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1081093008357	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1081093008358	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1081093008359	active site
1081093008360	intersubunit interface [polypeptide binding]; other site
1081093008361	zinc binding site [ion binding]; other site
1081093008362	Na+ binding site [ion binding]; other site
1081093008363	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1081093008364	Phosphoglycerate kinase; Region: PGK; pfam00162
1081093008365	substrate binding site [chemical binding]; other site
1081093008366	hinge regions; other site
1081093008367	ADP binding site [chemical binding]; other site
1081093008368	catalytic site [active]
1081093008369	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1081093008370	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1081093008371	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1081093008372	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1081093008373	trimer interface [polypeptide binding]; other site
1081093008374	putative Zn binding site [ion binding]; other site
1081093008375	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1081093008376	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1081093008377	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1081093008378	Walker A/P-loop; other site
1081093008379	ATP binding site [chemical binding]; other site
1081093008380	Q-loop/lid; other site
1081093008381	ABC transporter signature motif; other site
1081093008382	Walker B; other site
1081093008383	D-loop; other site
1081093008384	H-loop/switch region; other site
1081093008385	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1081093008386	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1081093008387	Walker A/P-loop; other site
1081093008388	ATP binding site [chemical binding]; other site
1081093008389	Q-loop/lid; other site
1081093008390	ABC transporter signature motif; other site
1081093008391	Walker B; other site
1081093008392	D-loop; other site
1081093008393	H-loop/switch region; other site
1081093008394	transketolase; Reviewed; Region: PRK12753
1081093008395	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1081093008396	TPP-binding site [chemical binding]; other site
1081093008397	dimer interface [polypeptide binding]; other site
1081093008398	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1081093008399	PYR/PP interface [polypeptide binding]; other site
1081093008400	dimer interface [polypeptide binding]; other site
1081093008401	TPP binding site [chemical binding]; other site
1081093008402	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1081093008403	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1081093008404	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1081093008405	agmatinase; Region: agmatinase; TIGR01230
1081093008406	oligomer interface [polypeptide binding]; other site
1081093008407	putative active site [active]
1081093008408	Mn binding site [ion binding]; other site
1081093008409	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1081093008410	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1081093008411	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
1081093008412	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1081093008413	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1081093008414	putative NAD(P) binding site [chemical binding]; other site
1081093008415	catalytic Zn binding site [ion binding]; other site
1081093008416	structural Zn binding site [ion binding]; other site
1081093008417	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1081093008418	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1081093008419	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1081093008420	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1081093008421	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093008422	DNA-binding site [nucleotide binding]; DNA binding site
1081093008423	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1081093008424	DNA phosphorothioation-dependent restriction protein DptH; Region: dnd_assoc_2; TIGR03237
1081093008425	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1081093008426	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1081093008427	dimer interface [polypeptide binding]; other site
1081093008428	active site
1081093008429	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1081093008430	catalytic residues [active]
1081093008431	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1081093008432	Virulence promoting factor; Region: YqgB; pfam11036
1081093008433	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1081093008434	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1081093008435	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1081093008436	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1081093008437	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1081093008438	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093008439	putative substrate translocation pore; other site
1081093008440	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093008441	hypothetical protein; Provisional; Region: PRK04860
1081093008442	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1081093008443	DNA-specific endonuclease I; Provisional; Region: PRK15137
1081093008444	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1081093008445	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1081093008446	RNA methyltransferase, RsmE family; Region: TIGR00046
1081093008447	glutathione synthetase; Provisional; Region: PRK05246
1081093008448	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1081093008449	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1081093008450	hypothetical protein; Validated; Region: PRK00228
1081093008451	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1081093008452	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1081093008453	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1081093008454	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1081093008455	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1081093008456	Walker A motif; other site
1081093008457	ATP binding site [chemical binding]; other site
1081093008458	Walker B motif; other site
1081093008459	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1081093008460	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1081093008461	catalytic residue [active]
1081093008462	YGGT family; Region: YGGT; pfam02325
1081093008463	YGGT family; Region: YGGT; pfam02325
1081093008464	hypothetical protein; Validated; Region: PRK05090
1081093008465	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1081093008466	active site
1081093008467	dimerization interface [polypeptide binding]; other site
1081093008468	HemN family oxidoreductase; Provisional; Region: PRK05660
1081093008469	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093008470	FeS/SAM binding site; other site
1081093008471	HemN C-terminal domain; Region: HemN_C; pfam06969
1081093008472	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1081093008473	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1081093008474	homodimer interface [polypeptide binding]; other site
1081093008475	active site
1081093008476	hypothetical protein; Provisional; Region: PRK10626
1081093008477	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1081093008478	hypothetical protein; Provisional; Region: PRK11702
1081093008479	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1081093008480	adenine DNA glycosylase; Provisional; Region: PRK10880
1081093008481	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1081093008482	minor groove reading motif; other site
1081093008483	helix-hairpin-helix signature motif; other site
1081093008484	substrate binding pocket [chemical binding]; other site
1081093008485	active site
1081093008486	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1081093008487	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1081093008488	DNA binding and oxoG recognition site [nucleotide binding]
1081093008489	oxidative damage protection protein; Provisional; Region: PRK05408
1081093008490	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1081093008491	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1081093008492	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1081093008493	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1081093008494	catalytic residue [active]
1081093008495	nucleoside transporter; Region: 2A0110; TIGR00889
1081093008496	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
1081093008497	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
1081093008498	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1081093008499	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1081093008500	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
1081093008501	putative active site [active]
1081093008502	putative catalytic site [active]
1081093008503	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1081093008504	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1081093008505	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093008506	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1081093008507	putative dimerization interface [polypeptide binding]; other site
1081093008508	putative substrate binding pocket [chemical binding]; other site
1081093008509	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1081093008510	Sulfatase; Region: Sulfatase; pfam00884
1081093008511	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1081093008512	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093008513	FeS/SAM binding site; other site
1081093008514	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1081093008515	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1081093008516	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093008517	DNA binding residues [nucleotide binding]
1081093008518	dimerization interface [polypeptide binding]; other site
1081093008519	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
1081093008520	Amino acid permease; Region: AA_permease_2; pfam13520
1081093008521	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
1081093008522	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
1081093008523	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1081093008524	NAD(P) binding site [chemical binding]; other site
1081093008525	catalytic residues [active]
1081093008526	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
1081093008527	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1081093008528	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1081093008529	active site
1081093008530	catalytic site [active]
1081093008531	Zn binding site [ion binding]; other site
1081093008532	tetramer interface [polypeptide binding]; other site
1081093008533	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1081093008534	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
1081093008535	putative active site [active]
1081093008536	catalytic triad [active]
1081093008537	putative dimer interface [polypeptide binding]; other site
1081093008538	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093008539	D-galactonate transporter; Region: 2A0114; TIGR00893
1081093008540	putative substrate translocation pore; other site
1081093008541	mannonate dehydratase; Provisional; Region: PRK03906
1081093008542	mannonate dehydratase; Region: uxuA; TIGR00695
1081093008543	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1081093008544	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1081093008545	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1081093008546	Glucuronate isomerase; Region: UxaC; pfam02614
1081093008547	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1081093008548	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1081093008549	dimer interface [polypeptide binding]; other site
1081093008550	putative CheW interface [polypeptide binding]; other site
1081093008551	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1081093008552	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1081093008553	CHAP domain; Region: CHAP; pfam05257
1081093008554	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1081093008555	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1081093008556	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
1081093008557	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1081093008558	putative ligand binding residues [chemical binding]; other site
1081093008559	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1081093008560	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1081093008561	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1081093008562	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
1081093008563	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
1081093008564	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1081093008565	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1081093008566	putative substrate-binding site; other site
1081093008567	nickel binding site [ion binding]; other site
1081093008568	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1081093008569	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1081093008570	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1081093008571	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1081093008572	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1081093008573	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1081093008574	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1081093008575	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1081093008576	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1081093008577	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1081093008578	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1081093008579	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093008580	dimerization interface [polypeptide binding]; other site
1081093008581	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1081093008582	dimer interface [polypeptide binding]; other site
1081093008583	putative CheW interface [polypeptide binding]; other site
1081093008584	hypothetical protein; Provisional; Region: PRK05208
1081093008585	oxidoreductase; Provisional; Region: PRK07985
1081093008586	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1081093008587	NAD binding site [chemical binding]; other site
1081093008588	metal binding site [ion binding]; metal-binding site
1081093008589	active site
1081093008590	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1081093008591	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1081093008592	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1081093008593	cystathionine beta-lyase; Provisional; Region: PRK08114
1081093008594	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1081093008595	homodimer interface [polypeptide binding]; other site
1081093008596	substrate-cofactor binding pocket; other site
1081093008597	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093008598	catalytic residue [active]
1081093008599	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1081093008600	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1081093008601	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1081093008602	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1081093008603	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093008604	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093008605	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1081093008606	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1081093008607	dimer interface [polypeptide binding]; other site
1081093008608	active site
1081093008609	metal binding site [ion binding]; metal-binding site
1081093008610	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1081093008611	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1081093008612	active site
1081093008613	catalytic tetrad [active]
1081093008614	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1081093008615	nucleotide binding site/active site [active]
1081093008616	catalytic residue [active]
1081093008617	hypothetical protein; Provisional; Region: PRK01254
1081093008618	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1081093008619	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1081093008620	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1081093008621	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1081093008622	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1081093008623	FtsI repressor; Provisional; Region: PRK10883
1081093008624	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1081093008625	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1081093008626	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1081093008627	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1081093008628	putative acyl-acceptor binding pocket; other site
1081093008629	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
1081093008630	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1081093008631	CAP-like domain; other site
1081093008632	active site
1081093008633	primary dimer interface [polypeptide binding]; other site
1081093008634	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1081093008635	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1081093008636	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093008637	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
1081093008638	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1081093008639	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1081093008640	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093008641	active site
1081093008642	phosphorylation site [posttranslational modification]
1081093008643	intermolecular recognition site; other site
1081093008644	dimerization interface [polypeptide binding]; other site
1081093008645	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093008646	DNA binding site [nucleotide binding]
1081093008647	sensor protein QseC; Provisional; Region: PRK10337
1081093008648	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1081093008649	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093008650	dimer interface [polypeptide binding]; other site
1081093008651	phosphorylation site [posttranslational modification]
1081093008652	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093008653	ATP binding site [chemical binding]; other site
1081093008654	Mg2+ binding site [ion binding]; other site
1081093008655	G-X-G motif; other site
1081093008656	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1081093008657	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1081093008658	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1081093008659	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093008660	ATP binding site [chemical binding]; other site
1081093008661	Mg2+ binding site [ion binding]; other site
1081093008662	G-X-G motif; other site
1081093008663	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1081093008664	anchoring element; other site
1081093008665	dimer interface [polypeptide binding]; other site
1081093008666	ATP binding site [chemical binding]; other site
1081093008667	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1081093008668	active site
1081093008669	metal binding site [ion binding]; metal-binding site
1081093008670	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1081093008671	esterase YqiA; Provisional; Region: PRK11071
1081093008672	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1081093008673	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1081093008674	active site
1081093008675	metal binding site [ion binding]; metal-binding site
1081093008676	hexamer interface [polypeptide binding]; other site
1081093008677	putative dehydrogenase; Provisional; Region: PRK11039
1081093008678	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1081093008679	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1081093008680	dimer interface [polypeptide binding]; other site
1081093008681	ADP-ribose binding site [chemical binding]; other site
1081093008682	active site
1081093008683	nudix motif; other site
1081093008684	metal binding site [ion binding]; metal-binding site
1081093008685	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1081093008686	hypothetical protein; Provisional; Region: PRK11653
1081093008687	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1081093008688	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1081093008689	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1081093008690	putative active site [active]
1081093008691	metal binding site [ion binding]; metal-binding site
1081093008692	zinc transporter ZupT; Provisional; Region: PRK04201
1081093008693	ZIP Zinc transporter; Region: Zip; pfam02535
1081093008694	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
1081093008695	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1081093008696	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1081093008697	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1081093008698	catalytic residues [active]
1081093008699	hinge region; other site
1081093008700	alpha helical domain; other site
1081093008701	putative disulfide oxidoreductase; Provisional; Region: PRK04307
1081093008702	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1081093008703	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1081093008704	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1081093008705	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
1081093008706	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
1081093008707	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1081093008708	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1081093008709	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1081093008710	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1081093008711	putative ribose interaction site [chemical binding]; other site
1081093008712	putative ADP binding site [chemical binding]; other site
1081093008713	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1081093008714	active site
1081093008715	nucleotide binding site [chemical binding]; other site
1081093008716	HIGH motif; other site
1081093008717	KMSKS motif; other site
1081093008718	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1081093008719	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1081093008720	metal binding triad; other site
1081093008721	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1081093008722	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1081093008723	metal binding triad; other site
1081093008724	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1081093008725	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1081093008726	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1081093008727	putative active site [active]
1081093008728	putative metal binding residues [ion binding]; other site
1081093008729	signature motif; other site
1081093008730	putative triphosphate binding site [ion binding]; other site
1081093008731	CHAD domain; Region: CHAD; pfam05235
1081093008732	SH3 domain-containing protein; Provisional; Region: PRK10884
1081093008733	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1081093008734	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1081093008735	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1081093008736	active site
1081093008737	NTP binding site [chemical binding]; other site
1081093008738	metal binding triad [ion binding]; metal-binding site
1081093008739	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1081093008740	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1081093008741	Zn2+ binding site [ion binding]; other site
1081093008742	Mg2+ binding site [ion binding]; other site
1081093008743	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1081093008744	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1081093008745	homooctamer interface [polypeptide binding]; other site
1081093008746	active site
1081093008747	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1081093008748	UGMP family protein; Validated; Region: PRK09604
1081093008749	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1081093008750	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1081093008751	DNA primase; Validated; Region: dnaG; PRK05667
1081093008752	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1081093008753	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1081093008754	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1081093008755	active site
1081093008756	metal binding site [ion binding]; metal-binding site
1081093008757	interdomain interaction site; other site
1081093008758	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1081093008759	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1081093008760	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1081093008761	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1081093008762	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1081093008763	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1081093008764	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1081093008765	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1081093008766	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1081093008767	DNA binding residues [nucleotide binding]
1081093008768	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1081093008769	active site
1081093008770	SUMO-1 interface [polypeptide binding]; other site
1081093008771	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1081093008772	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1081093008773	FAD binding pocket [chemical binding]; other site
1081093008774	FAD binding motif [chemical binding]; other site
1081093008775	phosphate binding motif [ion binding]; other site
1081093008776	NAD binding pocket [chemical binding]; other site
1081093008777	Predicted transcriptional regulators [Transcription]; Region: COG1695
1081093008778	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1081093008779	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1081093008780	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093008781	dimerization interface [polypeptide binding]; other site
1081093008782	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1081093008783	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1081093008784	dimer interface [polypeptide binding]; other site
1081093008785	putative CheW interface [polypeptide binding]; other site
1081093008786	PAS fold; Region: PAS_3; pfam08447
1081093008787	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1081093008788	putative active site [active]
1081093008789	heme pocket [chemical binding]; other site
1081093008790	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1081093008791	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1081093008792	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1081093008793	dimer interface [polypeptide binding]; other site
1081093008794	putative CheW interface [polypeptide binding]; other site
1081093008795	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1081093008796	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1081093008797	inhibitor-cofactor binding pocket; inhibition site
1081093008798	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093008799	catalytic residue [active]
1081093008800	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1081093008801	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1081093008802	active site
1081093008803	FMN binding site [chemical binding]; other site
1081093008804	2,4-decadienoyl-CoA binding site; other site
1081093008805	catalytic residue [active]
1081093008806	4Fe-4S cluster binding site [ion binding]; other site
1081093008807	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1081093008808	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1081093008809	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1081093008810	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093008811	S-adenosylmethionine binding site [chemical binding]; other site
1081093008812	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1081093008813	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1081093008814	putative active site [active]
1081093008815	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1081093008816	serine/threonine transporter SstT; Provisional; Region: PRK13628
1081093008817	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1081093008818	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1081093008819	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1081093008820	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1081093008821	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1081093008822	Bacterial protein of unknown function (DUF883); Region: DUF883; cl01888
1081093008823	Predicted membrane protein [Function unknown]; Region: COG5393
1081093008824	YqjK-like protein; Region: YqjK; pfam13997
1081093008825	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1081093008826	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1081093008827	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1081093008828	putative dimer interface [polypeptide binding]; other site
1081093008829	N-terminal domain interface [polypeptide binding]; other site
1081093008830	putative substrate binding pocket (H-site) [chemical binding]; other site
1081093008831	Predicted membrane protein [Function unknown]; Region: COG3152
1081093008832	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093008833	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1081093008834	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093008835	dimerization interface [polypeptide binding]; other site
1081093008836	Pirin-related protein [General function prediction only]; Region: COG1741
1081093008837	Pirin; Region: Pirin; pfam02678
1081093008838	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1081093008839	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1081093008840	Pyruvate formate lyase 1; Region: PFL1; cd01678
1081093008841	coenzyme A binding site [chemical binding]; other site
1081093008842	active site
1081093008843	catalytic residues [active]
1081093008844	glycine loop; other site
1081093008845	propionate/acetate kinase; Provisional; Region: PRK12379
1081093008846	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
1081093008847	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1081093008848	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1081093008849	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1081093008850	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1081093008851	tetramer interface [polypeptide binding]; other site
1081093008852	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093008853	catalytic residue [active]
1081093008854	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1081093008855	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093008856	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1081093008857	putative substrate binding pocket [chemical binding]; other site
1081093008858	putative dimerization interface [polypeptide binding]; other site
1081093008859	glycerate kinase I; Provisional; Region: PRK10342
1081093008860	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1081093008861	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1081093008862	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1081093008863	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1081093008864	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1081093008865	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1081093008866	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1081093008867	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1081093008868	intersubunit interface [polypeptide binding]; other site
1081093008869	active site
1081093008870	zinc binding site [ion binding]; other site
1081093008871	Na+ binding site [ion binding]; other site
1081093008872	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
1081093008873	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1081093008874	active site
1081093008875	phosphorylation site [posttranslational modification]
1081093008876	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1081093008877	active site
1081093008878	P-loop; other site
1081093008879	phosphorylation site [posttranslational modification]
1081093008880	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1081093008881	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1081093008882	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1081093008883	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1081093008884	putative NAD(P) binding site [chemical binding]; other site
1081093008885	catalytic Zn binding site [ion binding]; other site
1081093008886	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093008887	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1081093008888	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093008889	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1081093008890	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1081093008891	putative SAM binding site [chemical binding]; other site
1081093008892	putative homodimer interface [polypeptide binding]; other site
1081093008893	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1081093008894	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1081093008895	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1081093008896	putative ligand binding site [chemical binding]; other site
1081093008897	TIGR00252 family protein; Region: TIGR00252
1081093008898	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1081093008899	dimer interface [polypeptide binding]; other site
1081093008900	active site
1081093008901	outer membrane lipoprotein; Provisional; Region: PRK11023
1081093008902	BON domain; Region: BON; pfam04972
1081093008903	BON domain; Region: BON; pfam04972
1081093008904	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1081093008905	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1081093008906	NAD binding site [chemical binding]; other site
1081093008907	active site
1081093008908	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1081093008909	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1081093008910	proposed catalytic triad [active]
1081093008911	conserved cys residue [active]
1081093008912	hypothetical protein; Provisional; Region: PRK03467
1081093008913	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1081093008914	GIY-YIG motif/motif A; other site
1081093008915	putative active site [active]
1081093008916	putative metal binding site [ion binding]; other site
1081093008917	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1081093008918	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093008919	Coenzyme A binding pocket [chemical binding]; other site
1081093008920	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1081093008921	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1081093008922	Peptidase family U32; Region: Peptidase_U32; pfam01136
1081093008923	putative protease; Provisional; Region: PRK15447
1081093008924	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1081093008925	hypothetical protein; Provisional; Region: PRK10508
1081093008926	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1081093008927	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1081093008928	tryptophan permease; Provisional; Region: PRK10483
1081093008929	aromatic amino acid transport protein; Region: araaP; TIGR00837
1081093008930	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1081093008931	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1081093008932	ATP binding site [chemical binding]; other site
1081093008933	Mg++ binding site [ion binding]; other site
1081093008934	motif III; other site
1081093008935	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093008936	nucleotide binding region [chemical binding]; other site
1081093008937	ATP-binding site [chemical binding]; other site
1081093008938	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1081093008939	putative RNA binding site [nucleotide binding]; other site
1081093008940	lipoprotein NlpI; Provisional; Region: PRK11189
1081093008941	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1081093008942	binding surface
1081093008943	TPR motif; other site
1081093008944	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1081093008945	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1081093008946	RNase E interface [polypeptide binding]; other site
1081093008947	trimer interface [polypeptide binding]; other site
1081093008948	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1081093008949	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1081093008950	RNase E interface [polypeptide binding]; other site
1081093008951	trimer interface [polypeptide binding]; other site
1081093008952	active site
1081093008953	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1081093008954	putative nucleic acid binding region [nucleotide binding]; other site
1081093008955	G-X-X-G motif; other site
1081093008956	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1081093008957	RNA binding site [nucleotide binding]; other site
1081093008958	domain interface; other site
1081093008959	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1081093008960	16S/18S rRNA binding site [nucleotide binding]; other site
1081093008961	S13e-L30e interaction site [polypeptide binding]; other site
1081093008962	25S rRNA binding site [nucleotide binding]; other site
1081093008963	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1081093008964	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1081093008965	RNA binding site [nucleotide binding]; other site
1081093008966	active site
1081093008967	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1081093008968	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1081093008969	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1081093008970	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1081093008971	translation initiation factor IF-2; Region: IF-2; TIGR00487
1081093008972	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1081093008973	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1081093008974	G1 box; other site
1081093008975	putative GEF interaction site [polypeptide binding]; other site
1081093008976	GTP/Mg2+ binding site [chemical binding]; other site
1081093008977	Switch I region; other site
1081093008978	G2 box; other site
1081093008979	G3 box; other site
1081093008980	Switch II region; other site
1081093008981	G4 box; other site
1081093008982	G5 box; other site
1081093008983	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1081093008984	Translation-initiation factor 2; Region: IF-2; pfam11987
1081093008985	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1081093008986	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1081093008987	NusA N-terminal domain; Region: NusA_N; pfam08529
1081093008988	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1081093008989	RNA binding site [nucleotide binding]; other site
1081093008990	homodimer interface [polypeptide binding]; other site
1081093008991	NusA-like KH domain; Region: KH_5; pfam13184
1081093008992	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1081093008993	G-X-X-G motif; other site
1081093008994	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1081093008995	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1081093008996	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1081093008997	hypothetical protein; Provisional; Region: PRK14641
1081093008998	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1081093008999	putative oligomer interface [polypeptide binding]; other site
1081093009000	putative RNA binding site [nucleotide binding]; other site
1081093009001	argininosuccinate synthase; Validated; Region: PRK05370
1081093009002	argininosuccinate synthase; Provisional; Region: PRK13820
1081093009003	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1081093009004	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1081093009005	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1081093009006	active site
1081093009007	substrate binding site [chemical binding]; other site
1081093009008	metal binding site [ion binding]; metal-binding site
1081093009009	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1081093009010	dihydropteroate synthase; Region: DHPS; TIGR01496
1081093009011	substrate binding pocket [chemical binding]; other site
1081093009012	dimer interface [polypeptide binding]; other site
1081093009013	inhibitor binding site; inhibition site
1081093009014	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1081093009015	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093009016	Walker A motif; other site
1081093009017	ATP binding site [chemical binding]; other site
1081093009018	Walker B motif; other site
1081093009019	arginine finger; other site
1081093009020	Peptidase family M41; Region: Peptidase_M41; pfam01434
1081093009021	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1081093009022	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093009023	S-adenosylmethionine binding site [chemical binding]; other site
1081093009024	RNA-binding protein YhbY; Provisional; Region: PRK10343
1081093009025	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1081093009026	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1081093009027	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1081093009028	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1081093009029	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1081093009030	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1081093009031	GTP1/OBG; Region: GTP1_OBG; pfam01018
1081093009032	Obg GTPase; Region: Obg; cd01898
1081093009033	G1 box; other site
1081093009034	GTP/Mg2+ binding site [chemical binding]; other site
1081093009035	Switch I region; other site
1081093009036	G2 box; other site
1081093009037	G3 box; other site
1081093009038	Switch II region; other site
1081093009039	G4 box; other site
1081093009040	G5 box; other site
1081093009041	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1081093009042	EamA-like transporter family; Region: EamA; pfam00892
1081093009043	EamA-like transporter family; Region: EamA; pfam00892
1081093009044	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1081093009045	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1081093009046	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1081093009047	substrate binding pocket [chemical binding]; other site
1081093009048	chain length determination region; other site
1081093009049	substrate-Mg2+ binding site; other site
1081093009050	catalytic residues [active]
1081093009051	aspartate-rich region 1; other site
1081093009052	active site lid residues [active]
1081093009053	aspartate-rich region 2; other site
1081093009054	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1081093009055	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1081093009056	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1081093009057	hinge; other site
1081093009058	active site
1081093009059	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1081093009060	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1081093009061	anti sigma factor interaction site; other site
1081093009062	regulatory phosphorylation site [posttranslational modification]; other site
1081093009063	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1081093009064	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1081093009065	mce related protein; Region: MCE; pfam02470
1081093009066	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1081093009067	conserved hypothetical integral membrane protein; Region: TIGR00056
1081093009068	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1081093009069	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1081093009070	Walker A/P-loop; other site
1081093009071	ATP binding site [chemical binding]; other site
1081093009072	Q-loop/lid; other site
1081093009073	ABC transporter signature motif; other site
1081093009074	Walker B; other site
1081093009075	D-loop; other site
1081093009076	H-loop/switch region; other site
1081093009077	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1081093009078	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1081093009079	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1081093009080	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1081093009081	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1081093009082	putative active site [active]
1081093009083	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1081093009084	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1081093009085	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1081093009086	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1081093009087	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1081093009088	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1081093009089	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1081093009090	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1081093009091	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1081093009092	Walker A/P-loop; other site
1081093009093	ATP binding site [chemical binding]; other site
1081093009094	Q-loop/lid; other site
1081093009095	ABC transporter signature motif; other site
1081093009096	Walker B; other site
1081093009097	D-loop; other site
1081093009098	H-loop/switch region; other site
1081093009099	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1081093009100	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1081093009101	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1081093009102	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1081093009103	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1081093009104	30S subunit binding site; other site
1081093009105	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1081093009106	active site
1081093009107	phosphorylation site [posttranslational modification]
1081093009108	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
1081093009109	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1081093009110	dimerization domain swap beta strand [polypeptide binding]; other site
1081093009111	regulatory protein interface [polypeptide binding]; other site
1081093009112	active site
1081093009113	regulatory phosphorylation site [posttranslational modification]; other site
1081093009114	hypothetical protein; Provisional; Region: PRK10345
1081093009115	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1081093009116	Transglycosylase; Region: Transgly; cl17702
1081093009117	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1081093009118	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1081093009119	conserved cys residue [active]
1081093009120	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1081093009121	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1081093009122	putative active site [active]
1081093009123	heme pocket [chemical binding]; other site
1081093009124	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093009125	dimer interface [polypeptide binding]; other site
1081093009126	phosphorylation site [posttranslational modification]
1081093009127	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093009128	ATP binding site [chemical binding]; other site
1081093009129	Mg2+ binding site [ion binding]; other site
1081093009130	G-X-G motif; other site
1081093009131	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093009132	active site
1081093009133	phosphorylation site [posttranslational modification]
1081093009134	intermolecular recognition site; other site
1081093009135	dimerization interface [polypeptide binding]; other site
1081093009136	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1081093009137	putative binding surface; other site
1081093009138	active site
1081093009139	radical SAM protein, TIGR01212 family; Region: TIGR01212
1081093009140	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093009141	FeS/SAM binding site; other site
1081093009142	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1081093009143	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1081093009144	active site
1081093009145	dimer interface [polypeptide binding]; other site
1081093009146	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1081093009147	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1081093009148	active site
1081093009149	FMN binding site [chemical binding]; other site
1081093009150	substrate binding site [chemical binding]; other site
1081093009151	3Fe-4S cluster binding site [ion binding]; other site
1081093009152	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1081093009153	domain interface; other site
1081093009154	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1081093009155	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1081093009156	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093009157	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1081093009158	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1081093009159	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1081093009160	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1081093009161	Na binding site [ion binding]; other site
1081093009162	putative substrate binding site [chemical binding]; other site
1081093009163	cytosine deaminase; Provisional; Region: PRK09230
1081093009164	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1081093009165	active site
1081093009166	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1081093009167	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1081093009168	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1081093009169	nucleotide binding site [chemical binding]; other site
1081093009170	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1081093009171	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1081093009172	putative active site cavity [active]
1081093009173	putative sialic acid transporter; Provisional; Region: PRK03893
1081093009174	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093009175	putative substrate translocation pore; other site
1081093009176	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1081093009177	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1081093009178	inhibitor site; inhibition site
1081093009179	active site
1081093009180	dimer interface [polypeptide binding]; other site
1081093009181	catalytic residue [active]
1081093009182	transcriptional regulator NanR; Provisional; Region: PRK03837
1081093009183	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093009184	DNA-binding site [nucleotide binding]; DNA binding site
1081093009185	FCD domain; Region: FCD; pfam07729
1081093009186	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
1081093009187	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1081093009188	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1081093009189	C-terminal domain interface [polypeptide binding]; other site
1081093009190	putative GSH binding site (G-site) [chemical binding]; other site
1081093009191	dimer interface [polypeptide binding]; other site
1081093009192	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1081093009193	dimer interface [polypeptide binding]; other site
1081093009194	N-terminal domain interface [polypeptide binding]; other site
1081093009195	Family of unknown function (DUF695); Region: DUF695; pfam05117
1081093009196	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
1081093009197	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1081093009198	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1081093009199	23S rRNA interface [nucleotide binding]; other site
1081093009200	L3 interface [polypeptide binding]; other site
1081093009201	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1081093009202	hypothetical protein; Provisional; Region: PRK11677
1081093009203	serine endoprotease; Provisional; Region: PRK10139
1081093009204	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1081093009205	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1081093009206	protein binding site [polypeptide binding]; other site
1081093009207	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1081093009208	serine endoprotease; Provisional; Region: PRK10898
1081093009209	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1081093009210	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1081093009211	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1081093009212	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1081093009213	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1081093009214	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1081093009215	active site
1081093009216	catalytic residues [active]
1081093009217	metal binding site [ion binding]; metal-binding site
1081093009218	homodimer binding site [polypeptide binding]; other site
1081093009219	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1081093009220	carboxyltransferase (CT) interaction site; other site
1081093009221	biotinylation site [posttranslational modification]; other site
1081093009222	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1081093009223	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1081093009224	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1081093009225	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1081093009226	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1081093009227	transmembrane helices; other site
1081093009228	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1081093009229	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093009230	DNA-binding site [nucleotide binding]; DNA binding site
1081093009231	FCD domain; Region: FCD; pfam07729
1081093009232	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1081093009233	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093009234	DNA-binding site [nucleotide binding]; DNA binding site
1081093009235	malate dehydrogenase; Provisional; Region: PRK05086
1081093009236	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1081093009237	NAD binding site [chemical binding]; other site
1081093009238	dimerization interface [polypeptide binding]; other site
1081093009239	Substrate binding site [chemical binding]; other site
1081093009240	arginine repressor; Provisional; Region: PRK05066
1081093009241	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1081093009242	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1081093009243	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093009244	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093009245	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1081093009246	RNAase interaction site [polypeptide binding]; other site
1081093009247	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1081093009248	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1081093009249	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1081093009250	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1081093009251	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093009252	efflux system membrane protein; Provisional; Region: PRK11594
1081093009253	transcriptional regulator; Provisional; Region: PRK10632
1081093009254	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093009255	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1081093009256	putative effector binding pocket; other site
1081093009257	dimerization interface [polypeptide binding]; other site
1081093009258	protease TldD; Provisional; Region: tldD; PRK10735
1081093009259	Protein of unknown function; Region: DUF3971; pfam13116
1081093009260	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1081093009261	ribonuclease G; Provisional; Region: PRK11712
1081093009262	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1081093009263	homodimer interface [polypeptide binding]; other site
1081093009264	oligonucleotide binding site [chemical binding]; other site
1081093009265	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1081093009266	Maf-like protein; Region: Maf; pfam02545
1081093009267	active site
1081093009268	dimer interface [polypeptide binding]; other site
1081093009269	rod shape-determining protein MreD; Provisional; Region: PRK11060
1081093009270	rod shape-determining protein MreC; Region: mreC; TIGR00219
1081093009271	rod shape-determining protein MreC; Region: MreC; pfam04085
1081093009272	rod shape-determining protein MreB; Provisional; Region: PRK13927
1081093009273	MreB and similar proteins; Region: MreB_like; cd10225
1081093009274	nucleotide binding site [chemical binding]; other site
1081093009275	Mg binding site [ion binding]; other site
1081093009276	putative protofilament interaction site [polypeptide binding]; other site
1081093009277	RodZ interaction site [polypeptide binding]; other site
1081093009278	regulatory protein CsrD; Provisional; Region: PRK11059
1081093009279	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093009280	metal binding site [ion binding]; metal-binding site
1081093009281	active site
1081093009282	I-site; other site
1081093009283	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093009284	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1081093009285	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1081093009286	NADP binding site [chemical binding]; other site
1081093009287	dimer interface [polypeptide binding]; other site
1081093009288	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1081093009289	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1081093009290	Moco binding site; other site
1081093009291	metal coordination site [ion binding]; other site
1081093009292	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1081093009293	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1081093009294	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1081093009295	carboxyltransferase (CT) interaction site; other site
1081093009296	biotinylation site [posttranslational modification]; other site
1081093009297	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1081093009298	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1081093009299	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1081093009300	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1081093009301	hypothetical protein; Provisional; Region: PRK10633
1081093009302	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1081093009303	Na binding site [ion binding]; other site
1081093009304	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1081093009305	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1081093009306	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
1081093009307	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1081093009308	FMN binding site [chemical binding]; other site
1081093009309	active site
1081093009310	catalytic residues [active]
1081093009311	substrate binding site [chemical binding]; other site
1081093009312	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1081093009313	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1081093009314	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1081093009315	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093009316	DNA methylase; Region: N6_N4_Mtase; pfam01555
1081093009317	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1081093009318	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1081093009319	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1081093009320	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1081093009321	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093009322	metal binding site [ion binding]; metal-binding site
1081093009323	active site
1081093009324	I-site; other site
1081093009325	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093009326	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1081093009327	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093009328	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1081093009329	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1081093009330	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1081093009331	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093009332	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1081093009333	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1081093009334	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1081093009335	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1081093009336	purine monophosphate binding site [chemical binding]; other site
1081093009337	dimer interface [polypeptide binding]; other site
1081093009338	putative catalytic residues [active]
1081093009339	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1081093009340	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1081093009341	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1081093009342	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1081093009343	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1081093009344	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1081093009345	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093009346	active site
1081093009347	phosphorylation site [posttranslational modification]
1081093009348	intermolecular recognition site; other site
1081093009349	dimerization interface [polypeptide binding]; other site
1081093009350	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093009351	Walker A motif; other site
1081093009352	ATP binding site [chemical binding]; other site
1081093009353	Walker B motif; other site
1081093009354	arginine finger; other site
1081093009355	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1081093009356	sensor protein ZraS; Provisional; Region: PRK10364
1081093009357	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093009358	dimer interface [polypeptide binding]; other site
1081093009359	phosphorylation site [posttranslational modification]
1081093009360	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093009361	ATP binding site [chemical binding]; other site
1081093009362	Mg2+ binding site [ion binding]; other site
1081093009363	G-X-G motif; other site
1081093009364	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1081093009365	dimer interface [polypeptide binding]; other site
1081093009366	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1081093009367	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1081093009368	IHF dimer interface [polypeptide binding]; other site
1081093009369	IHF - DNA interface [nucleotide binding]; other site
1081093009370	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1081093009371	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1081093009372	Active_site [active]
1081093009373	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1081093009374	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1081093009375	substrate binding site [chemical binding]; other site
1081093009376	active site
1081093009377	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1081093009378	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1081093009379	ThiC-associated domain; Region: ThiC-associated; pfam13667
1081093009380	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1081093009381	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1081093009382	thiamine phosphate binding site [chemical binding]; other site
1081093009383	active site
1081093009384	pyrophosphate binding site [ion binding]; other site
1081093009385	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1081093009386	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1081093009387	ATP binding site [chemical binding]; other site
1081093009388	substrate interface [chemical binding]; other site
1081093009389	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1081093009390	thiS-thiF/thiG interaction site; other site
1081093009391	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1081093009392	ThiS interaction site; other site
1081093009393	putative active site [active]
1081093009394	tetramer interface [polypeptide binding]; other site
1081093009395	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1081093009396	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093009397	FeS/SAM binding site; other site
1081093009398	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1081093009399	type III secretion system protein; Provisional; Region: PRK15384
1081093009400	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
1081093009401	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1081093009402	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1081093009403	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1081093009404	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1081093009405	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1081093009406	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1081093009407	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1081093009408	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1081093009409	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1081093009410	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1081093009411	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1081093009412	DNA binding site [nucleotide binding]
1081093009413	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1081093009414	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1081093009415	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1081093009416	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1081093009417	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1081093009418	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1081093009419	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1081093009420	RPB3 interaction site [polypeptide binding]; other site
1081093009421	RPB1 interaction site [polypeptide binding]; other site
1081093009422	RPB11 interaction site [polypeptide binding]; other site
1081093009423	RPB10 interaction site [polypeptide binding]; other site
1081093009424	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1081093009425	core dimer interface [polypeptide binding]; other site
1081093009426	peripheral dimer interface [polypeptide binding]; other site
1081093009427	L10 interface [polypeptide binding]; other site
1081093009428	L11 interface [polypeptide binding]; other site
1081093009429	putative EF-Tu interaction site [polypeptide binding]; other site
1081093009430	putative EF-G interaction site [polypeptide binding]; other site
1081093009431	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1081093009432	23S rRNA interface [nucleotide binding]; other site
1081093009433	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1081093009434	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1081093009435	mRNA/rRNA interface [nucleotide binding]; other site
1081093009436	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1081093009437	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1081093009438	L7/L12 interface [polypeptide binding]; other site
1081093009439	23S rRNA interface [nucleotide binding]; other site
1081093009440	L25 interface [polypeptide binding]; other site
1081093009441	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1081093009442	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1081093009443	putative homodimer interface [polypeptide binding]; other site
1081093009444	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1081093009445	heterodimer interface [polypeptide binding]; other site
1081093009446	homodimer interface [polypeptide binding]; other site
1081093009447	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1081093009448	elongation factor Tu; Reviewed; Region: PRK00049
1081093009449	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1081093009450	G1 box; other site
1081093009451	GEF interaction site [polypeptide binding]; other site
1081093009452	GTP/Mg2+ binding site [chemical binding]; other site
1081093009453	Switch I region; other site
1081093009454	G2 box; other site
1081093009455	G3 box; other site
1081093009456	Switch II region; other site
1081093009457	G4 box; other site
1081093009458	G5 box; other site
1081093009459	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1081093009460	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1081093009461	Antibiotic Binding Site [chemical binding]; other site
1081093009462	pantothenate kinase; Provisional; Region: PRK05439
1081093009463	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1081093009464	ATP-binding site [chemical binding]; other site
1081093009465	CoA-binding site [chemical binding]; other site
1081093009466	Mg2+-binding site [ion binding]; other site
1081093009467	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1081093009468	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1081093009469	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1081093009470	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1081093009471	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1081093009472	FAD binding domain; Region: FAD_binding_4; pfam01565
1081093009473	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1081093009474	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1081093009475	hypothetical protein; Provisional; Region: PRK11568
1081093009476	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1081093009477	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1081093009478	proline dipeptidase; Provisional; Region: PRK13607
1081093009479	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1081093009480	active site
1081093009481	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1081093009482	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1081093009483	substrate binding site [chemical binding]; other site
1081093009484	oxyanion hole (OAH) forming residues; other site
1081093009485	trimer interface [polypeptide binding]; other site
1081093009486	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1081093009487	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1081093009488	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1081093009489	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1081093009490	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1081093009491	dimer interface [polypeptide binding]; other site
1081093009492	active site
1081093009493	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1081093009494	FMN reductase; Validated; Region: fre; PRK08051
1081093009495	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1081093009496	FAD binding pocket [chemical binding]; other site
1081093009497	FAD binding motif [chemical binding]; other site
1081093009498	phosphate binding motif [ion binding]; other site
1081093009499	beta-alpha-beta structure motif; other site
1081093009500	NAD binding pocket [chemical binding]; other site
1081093009501	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1081093009502	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1081093009503	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1081093009504	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1081093009505	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1081093009506	active site
1081093009507	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1081093009508	sec-independent translocase; Provisional; Region: PRK01770
1081093009509	sec-independent translocase; Provisional; Region: tatB; PRK00404
1081093009510	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1081093009511	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1081093009512	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1081093009513	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1081093009514	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1081093009515	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1081093009516	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093009517	S-adenosylmethionine binding site [chemical binding]; other site
1081093009518	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1081093009519	DNA recombination protein RmuC; Provisional; Region: PRK10361
1081093009520	RmuC family; Region: RmuC; pfam02646
1081093009521	uridine phosphorylase; Provisional; Region: PRK11178
1081093009522	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1081093009523	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1081093009524	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1081093009525	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093009526	FeS/SAM binding site; other site
1081093009527	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1081093009528	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1081093009529	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1081093009530	THF binding site; other site
1081093009531	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1081093009532	substrate binding site [chemical binding]; other site
1081093009533	THF binding site; other site
1081093009534	zinc-binding site [ion binding]; other site
1081093009535	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1081093009536	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093009537	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1081093009538	putative dimerization interface [polypeptide binding]; other site
1081093009539	putative hydrolase; Provisional; Region: PRK10976
1081093009540	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093009541	active site
1081093009542	motif I; other site
1081093009543	motif II; other site
1081093009544	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093009545	lysophospholipase L2; Provisional; Region: PRK10749
1081093009546	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1081093009547	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1081093009548	threonine efflux system; Provisional; Region: PRK10229
1081093009549	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1081093009550	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1081093009551	ATP binding site [chemical binding]; other site
1081093009552	putative Mg++ binding site [ion binding]; other site
1081093009553	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093009554	nucleotide binding region [chemical binding]; other site
1081093009555	ATP-binding site [chemical binding]; other site
1081093009556	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1081093009557	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1081093009558	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1081093009559	dimerization interface [polypeptide binding]; other site
1081093009560	substrate binding site [chemical binding]; other site
1081093009561	active site
1081093009562	calcium binding site [ion binding]; other site
1081093009563	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1081093009564	CoenzymeA binding site [chemical binding]; other site
1081093009565	subunit interaction site [polypeptide binding]; other site
1081093009566	PHB binding site; other site
1081093009567	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1081093009568	EamA-like transporter family; Region: EamA; cl17759
1081093009569	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1081093009570	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1081093009571	Cl binding site [ion binding]; other site
1081093009572	oligomer interface [polypeptide binding]; other site
1081093009573	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1081093009574	Part of AAA domain; Region: AAA_19; pfam13245
1081093009575	Family description; Region: UvrD_C_2; pfam13538
1081093009576	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1081093009577	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093009578	motif II; other site
1081093009579	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1081093009580	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1081093009581	active site
1081093009582	Int/Topo IB signature motif; other site
1081093009583	hypothetical protein; Provisional; Region: PRK10963
1081093009584	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1081093009585	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1081093009586	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1081093009587	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1081093009588	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
1081093009589	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1081093009590	putative iron binding site [ion binding]; other site
1081093009591	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1081093009592	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1081093009593	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1081093009594	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1081093009595	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1081093009596	domain interfaces; other site
1081093009597	active site
1081093009598	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1081093009599	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1081093009600	active site
1081093009601	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1081093009602	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1081093009603	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1081093009604	HemY protein N-terminus; Region: HemY_N; pfam07219
1081093009605	putative transport protein YifK; Provisional; Region: PRK10746
1081093009606	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1081093009607	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1081093009608	putative common antigen polymerase; Provisional; Region: PRK02975
1081093009609	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1081093009610	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1081093009611	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1081093009612	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1081093009613	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1081093009614	inhibitor-cofactor binding pocket; inhibition site
1081093009615	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093009616	catalytic residue [active]
1081093009617	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
1081093009618	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1081093009619	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1081093009620	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1081093009621	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1081093009622	NAD binding site [chemical binding]; other site
1081093009623	substrate binding site [chemical binding]; other site
1081093009624	homodimer interface [polypeptide binding]; other site
1081093009625	active site
1081093009626	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1081093009627	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1081093009628	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1081093009629	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
1081093009630	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1081093009631	homodimer interface [polypeptide binding]; other site
1081093009632	active site
1081093009633	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1081093009634	Chain length determinant protein; Region: Wzz; pfam02706
1081093009635	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1081093009636	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1081093009637	Mg++ binding site [ion binding]; other site
1081093009638	putative catalytic motif [active]
1081093009639	substrate binding site [chemical binding]; other site
1081093009640	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1081093009641	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1081093009642	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1081093009643	RNA binding site [nucleotide binding]; other site
1081093009644	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1081093009645	multimer interface [polypeptide binding]; other site
1081093009646	Walker A motif; other site
1081093009647	ATP binding site [chemical binding]; other site
1081093009648	Walker B motif; other site
1081093009649	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1081093009650	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1081093009651	catalytic residues [active]
1081093009652	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1081093009653	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1081093009654	ATP binding site [chemical binding]; other site
1081093009655	Mg++ binding site [ion binding]; other site
1081093009656	motif III; other site
1081093009657	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093009658	nucleotide binding region [chemical binding]; other site
1081093009659	ATP-binding site [chemical binding]; other site
1081093009660	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1081093009661	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1081093009662	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1081093009663	Part of AAA domain; Region: AAA_19; pfam13245
1081093009664	Family description; Region: UvrD_C_2; pfam13538
1081093009665	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1081093009666	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1081093009667	ketol-acid reductoisomerase; Validated; Region: PRK05225
1081093009668	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1081093009669	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1081093009670	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1081093009671	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093009672	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1081093009673	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1081093009674	putative dimerization interface [polypeptide binding]; other site
1081093009675	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
1081093009676	Phage-related protein [Function unknown]; Region: COG4679
1081093009677	threonine dehydratase; Reviewed; Region: PRK09224
1081093009678	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1081093009679	tetramer interface [polypeptide binding]; other site
1081093009680	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093009681	catalytic residue [active]
1081093009682	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1081093009683	putative Ile/Val binding site [chemical binding]; other site
1081093009684	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1081093009685	putative Ile/Val binding site [chemical binding]; other site
1081093009686	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1081093009687	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1081093009688	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1081093009689	homodimer interface [polypeptide binding]; other site
1081093009690	substrate-cofactor binding pocket; other site
1081093009691	catalytic residue [active]
1081093009692	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1081093009693	putative ATP-dependent protease; Provisional; Region: PRK09862
1081093009694	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1081093009695	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093009696	Walker A motif; other site
1081093009697	ATP binding site [chemical binding]; other site
1081093009698	Walker B motif; other site
1081093009699	arginine finger; other site
1081093009700	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1081093009701	hypothetical protein; Provisional; Region: PRK11027
1081093009702	transcriptional regulator HdfR; Provisional; Region: PRK03601
1081093009703	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093009704	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1081093009705	dimerization interface [polypeptide binding]; other site
1081093009706	glutamate racemase; Provisional; Region: PRK00865
1081093009707	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1081093009708	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1081093009709	N-terminal plug; other site
1081093009710	ligand-binding site [chemical binding]; other site
1081093009711	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1081093009712	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093009713	S-adenosylmethionine binding site [chemical binding]; other site
1081093009714	hypothetical protein; Provisional; Region: PRK11056
1081093009715	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1081093009716	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093009717	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1081093009718	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093009719	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1081093009720	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1081093009721	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093009722	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1081093009723	dimerization interface [polypeptide binding]; other site
1081093009724	argininosuccinate lyase; Provisional; Region: PRK04833
1081093009725	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1081093009726	active sites [active]
1081093009727	tetramer interface [polypeptide binding]; other site
1081093009728	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1081093009729	nucleotide binding site [chemical binding]; other site
1081093009730	N-acetyl-L-glutamate binding site [chemical binding]; other site
1081093009731	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1081093009732	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1081093009733	acetylornithine deacetylase; Provisional; Region: PRK05111
1081093009734	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1081093009735	metal binding site [ion binding]; metal-binding site
1081093009736	putative dimer interface [polypeptide binding]; other site
1081093009737	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1081093009738	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1081093009739	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1081093009740	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093009741	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1081093009742	active site
1081093009743	P-loop; other site
1081093009744	phosphorylation site [posttranslational modification]
1081093009745	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093009746	FeS/SAM binding site; other site
1081093009747	pyruvate formate lyase II activase; Provisional; Region: PRK10076
1081093009748	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1081093009749	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1081093009750	dimer interface [polypeptide binding]; other site
1081093009751	active site
1081093009752	glycine loop; other site
1081093009753	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1081093009754	active site
1081093009755	P-loop; other site
1081093009756	phosphorylation site [posttranslational modification]
1081093009757	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1081093009758	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1081093009759	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1081093009760	dimerization domain swap beta strand [polypeptide binding]; other site
1081093009761	regulatory protein interface [polypeptide binding]; other site
1081093009762	active site
1081093009763	regulatory phosphorylation site [posttranslational modification]; other site
1081093009764	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1081093009765	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1081093009766	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1081093009767	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1081093009768	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1081093009769	active site
1081093009770	phosphorylation site [posttranslational modification]
1081093009771	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1081093009772	active site
1081093009773	intersubunit interactions; other site
1081093009774	catalytic residue [active]
1081093009775	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1081093009776	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1081093009777	dimer interface [polypeptide binding]; other site
1081093009778	active site
1081093009779	metal binding site [ion binding]; metal-binding site
1081093009780	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
1081093009781	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1081093009782	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1081093009783	heme binding site [chemical binding]; other site
1081093009784	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1081093009785	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1081093009786	FAD binding site [chemical binding]; other site
1081093009787	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1081093009788	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093009789	DNA-binding site [nucleotide binding]; DNA binding site
1081093009790	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093009791	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093009792	homodimer interface [polypeptide binding]; other site
1081093009793	catalytic residue [active]
1081093009794	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
1081093009795	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1081093009796	dimer interface [polypeptide binding]; other site
1081093009797	active site
1081093009798	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1081093009799	folate binding site [chemical binding]; other site
1081093009800	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1081093009801	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1081093009802	active site
1081093009803	metal binding site [ion binding]; metal-binding site
1081093009804	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1081093009805	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1081093009806	mechanosensitive channel MscS; Provisional; Region: PRK10334
1081093009807	Conserved TM helix; Region: TM_helix; pfam05552
1081093009808	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1081093009809	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1081093009810	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1081093009811	putative catalytic residues [active]
1081093009812	putative nucleotide binding site [chemical binding]; other site
1081093009813	putative aspartate binding site [chemical binding]; other site
1081093009814	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1081093009815	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1081093009816	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1081093009817	cystathionine gamma-synthase; Provisional; Region: PRK08045
1081093009818	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1081093009819	homodimer interface [polypeptide binding]; other site
1081093009820	substrate-cofactor binding pocket; other site
1081093009821	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093009822	catalytic residue [active]
1081093009823	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1081093009824	dimerization interface [polypeptide binding]; other site
1081093009825	DNA binding site [nucleotide binding]
1081093009826	corepressor binding sites; other site
1081093009827	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1081093009828	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
1081093009829	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1081093009830	primosome assembly protein PriA; Validated; Region: PRK05580
1081093009831	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1081093009832	ATP binding site [chemical binding]; other site
1081093009833	putative Mg++ binding site [ion binding]; other site
1081093009834	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1081093009835	ATP-binding site [chemical binding]; other site
1081093009836	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093009837	DNA binding site [nucleotide binding]
1081093009838	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1081093009839	domain linker motif; other site
1081093009840	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1081093009841	dimerization interface [polypeptide binding]; other site
1081093009842	ligand binding site [chemical binding]; other site
1081093009843	essential cell division protein FtsN; Provisional; Region: PRK10927
1081093009844	cell division protein FtsN; Provisional; Region: PRK12757
1081093009845	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1081093009846	active site
1081093009847	HslU subunit interaction site [polypeptide binding]; other site
1081093009848	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1081093009849	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093009850	Walker A motif; other site
1081093009851	ATP binding site [chemical binding]; other site
1081093009852	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1081093009853	Walker B motif; other site
1081093009854	arginine finger; other site
1081093009855	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1081093009856	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1081093009857	UbiA prenyltransferase family; Region: UbiA; pfam01040
1081093009858	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1081093009859	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1081093009860	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1081093009861	amphipathic channel; other site
1081093009862	Asn-Pro-Ala signature motifs; other site
1081093009863	glycerol kinase; Provisional; Region: glpK; PRK00047
1081093009864	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1081093009865	N- and C-terminal domain interface [polypeptide binding]; other site
1081093009866	active site
1081093009867	MgATP binding site [chemical binding]; other site
1081093009868	catalytic site [active]
1081093009869	metal binding site [ion binding]; metal-binding site
1081093009870	glycerol binding site [chemical binding]; other site
1081093009871	homotetramer interface [polypeptide binding]; other site
1081093009872	homodimer interface [polypeptide binding]; other site
1081093009873	FBP binding site [chemical binding]; other site
1081093009874	protein IIAGlc interface [polypeptide binding]; other site
1081093009875	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1081093009876	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1081093009877	putative active site [active]
1081093009878	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1081093009879	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1081093009880	FAD binding pocket [chemical binding]; other site
1081093009881	FAD binding motif [chemical binding]; other site
1081093009882	phosphate binding motif [ion binding]; other site
1081093009883	beta-alpha-beta structure motif; other site
1081093009884	NAD binding pocket [chemical binding]; other site
1081093009885	Predicted membrane protein [Function unknown]; Region: COG3152
1081093009886	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1081093009887	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1081093009888	triosephosphate isomerase; Provisional; Region: PRK14567
1081093009889	substrate binding site [chemical binding]; other site
1081093009890	dimer interface [polypeptide binding]; other site
1081093009891	catalytic triad [active]
1081093009892	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1081093009893	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1081093009894	substrate binding site [chemical binding]; other site
1081093009895	hexamer interface [polypeptide binding]; other site
1081093009896	metal binding site [ion binding]; metal-binding site
1081093009897	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1081093009898	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1081093009899	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1081093009900	putative active site; other site
1081093009901	catalytic residue [active]
1081093009902	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1081093009903	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1081093009904	ligand binding site [chemical binding]; other site
1081093009905	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1081093009906	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1081093009907	TM-ABC transporter signature motif; other site
1081093009908	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1081093009909	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1081093009910	TM-ABC transporter signature motif; other site
1081093009911	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1081093009912	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1081093009913	Walker A/P-loop; other site
1081093009914	ATP binding site [chemical binding]; other site
1081093009915	Q-loop/lid; other site
1081093009916	ABC transporter signature motif; other site
1081093009917	Walker B; other site
1081093009918	D-loop; other site
1081093009919	H-loop/switch region; other site
1081093009920	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1081093009921	transcriptional regulator LsrR; Provisional; Region: PRK15418
1081093009922	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1081093009923	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1081093009924	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1081093009925	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
1081093009926	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1081093009927	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093009928	DNA-binding site [nucleotide binding]; DNA binding site
1081093009929	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
1081093009930	UTRA domain; Region: UTRA; pfam07702
1081093009931	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1081093009932	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093009933	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1081093009934	putative substrate binding site [chemical binding]; other site
1081093009935	putative ATP binding site [chemical binding]; other site
1081093009936	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1081093009937	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1081093009938	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1081093009939	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1081093009940	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093009941	substrate binding pocket [chemical binding]; other site
1081093009942	membrane-bound complex binding site; other site
1081093009943	hinge residues; other site
1081093009944	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1081093009945	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1081093009946	active site
1081093009947	ADP/pyrophosphate binding site [chemical binding]; other site
1081093009948	dimerization interface [polypeptide binding]; other site
1081093009949	allosteric effector site; other site
1081093009950	fructose-1,6-bisphosphate binding site; other site
1081093009951	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1081093009952	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1081093009953	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1081093009954	dimer interface [polypeptide binding]; other site
1081093009955	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1081093009956	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093009957	active site
1081093009958	intermolecular recognition site; other site
1081093009959	dimerization interface [polypeptide binding]; other site
1081093009960	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093009961	DNA binding site [nucleotide binding]
1081093009962	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1081093009963	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093009964	dimerization interface [polypeptide binding]; other site
1081093009965	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093009966	dimer interface [polypeptide binding]; other site
1081093009967	phosphorylation site [posttranslational modification]
1081093009968	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093009969	ATP binding site [chemical binding]; other site
1081093009970	Mg2+ binding site [ion binding]; other site
1081093009971	G-X-G motif; other site
1081093009972	SnoaL-like domain; Region: SnoaL_2; pfam12680
1081093009973	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1081093009974	MOSC domain; Region: MOSC; pfam03473
1081093009975	3-alpha domain; Region: 3-alpha; pfam03475
1081093009976	superoxide dismutase; Provisional; Region: PRK10925
1081093009977	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1081093009978	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1081093009979	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1081093009980	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1081093009981	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1081093009982	DctM-like transporters; Region: DctM; pfam06808
1081093009983	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1081093009984	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1081093009985	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
1081093009986	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1081093009987	transcriptional activator RhaR; Provisional; Region: PRK13502
1081093009988	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1081093009989	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093009990	transcriptional activator RhaS; Provisional; Region: PRK13503
1081093009991	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1081093009992	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093009993	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093009994	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1081093009995	N- and C-terminal domain interface [polypeptide binding]; other site
1081093009996	active site
1081093009997	putative catalytic site [active]
1081093009998	metal binding site [ion binding]; metal-binding site
1081093009999	ATP binding site [chemical binding]; other site
1081093010000	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1081093010001	carbohydrate binding site [chemical binding]; other site
1081093010002	L-rhamnose isomerase; Provisional; Region: PRK01076
1081093010003	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1081093010004	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1081093010005	intersubunit interface [polypeptide binding]; other site
1081093010006	active site
1081093010007	Zn2+ binding site [ion binding]; other site
1081093010008	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1081093010009	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093010010	non-specific DNA binding site [nucleotide binding]; other site
1081093010011	salt bridge; other site
1081093010012	sequence-specific DNA binding site [nucleotide binding]; other site
1081093010013	Cupin domain; Region: Cupin_2; cl17218
1081093010014	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1081093010015	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1081093010016	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1081093010017	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1081093010018	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1081093010019	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1081093010020	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1081093010021	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1081093010022	Predicted transcriptional regulator [Transcription]; Region: COG2944
1081093010023	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093010024	non-specific DNA binding site [nucleotide binding]; other site
1081093010025	salt bridge; other site
1081093010026	sequence-specific DNA binding site [nucleotide binding]; other site
1081093010027	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
1081093010028	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1081093010029	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
1081093010030	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093010031	non-specific DNA binding site [nucleotide binding]; other site
1081093010032	salt bridge; other site
1081093010033	sequence-specific DNA binding site [nucleotide binding]; other site
1081093010034	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093010035	Coenzyme A binding pocket [chemical binding]; other site
1081093010036	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1081093010037	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1081093010038	putative active site [active]
1081093010039	dimerization interface [polypeptide binding]; other site
1081093010040	putative tRNAtyr binding site [nucleotide binding]; other site
1081093010041	hypothetical protein; Reviewed; Region: PRK01637
1081093010042	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1081093010043	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093010044	motif II; other site
1081093010045	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093010046	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1081093010047	putative DNA binding site [nucleotide binding]; other site
1081093010048	putative Zn2+ binding site [ion binding]; other site
1081093010049	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093010050	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093010051	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
1081093010052	substrate binding site [chemical binding]; other site
1081093010053	ATP binding site [chemical binding]; other site
1081093010054	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1081093010055	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1081093010056	Class I aldolases; Region: Aldolase_Class_I; cl17187
1081093010057	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
1081093010058	dimerization interface [polypeptide binding]; other site
1081093010059	putative active cleft [active]
1081093010060	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
1081093010061	active site
1081093010062	catalytic residues [active]
1081093010063	alpha-glucosidase; Provisional; Region: PRK10426
1081093010064	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1081093010065	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
1081093010066	putative active site [active]
1081093010067	putative catalytic site [active]
1081093010068	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1081093010069	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1081093010070	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093010071	putative substrate translocation pore; other site
1081093010072	outer membrane porin L; Provisional; Region: ompL; PRK09980
1081093010073	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1081093010074	Leucine-rich repeats; other site
1081093010075	Substrate binding site [chemical binding]; other site
1081093010076	Sulfatase; Region: Sulfatase; cl17466
1081093010077	coproporphyrinogen III oxidase; Validated; Region: PRK08208
1081093010078	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093010079	FeS/SAM binding site; other site
1081093010080	HemN C-terminal domain; Region: HemN_C; pfam06969
1081093010081	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093010082	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1081093010083	active site
1081093010084	motif I; other site
1081093010085	motif II; other site
1081093010086	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093010087	GTP-binding protein; Provisional; Region: PRK10218
1081093010088	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1081093010089	G1 box; other site
1081093010090	putative GEF interaction site [polypeptide binding]; other site
1081093010091	GTP/Mg2+ binding site [chemical binding]; other site
1081093010092	Switch I region; other site
1081093010093	G2 box; other site
1081093010094	G3 box; other site
1081093010095	Switch II region; other site
1081093010096	G4 box; other site
1081093010097	G5 box; other site
1081093010098	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1081093010099	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1081093010100	glutamine synthetase; Provisional; Region: glnA; PRK09469
1081093010101	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1081093010102	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1081093010103	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1081093010104	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1081093010105	putative active site [active]
1081093010106	heme pocket [chemical binding]; other site
1081093010107	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093010108	dimer interface [polypeptide binding]; other site
1081093010109	phosphorylation site [posttranslational modification]
1081093010110	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093010111	ATP binding site [chemical binding]; other site
1081093010112	Mg2+ binding site [ion binding]; other site
1081093010113	G-X-G motif; other site
1081093010114	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1081093010115	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093010116	active site
1081093010117	phosphorylation site [posttranslational modification]
1081093010118	intermolecular recognition site; other site
1081093010119	dimerization interface [polypeptide binding]; other site
1081093010120	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093010121	Walker A motif; other site
1081093010122	ATP binding site [chemical binding]; other site
1081093010123	Walker B motif; other site
1081093010124	arginine finger; other site
1081093010125	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1081093010126	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1081093010127	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093010128	FeS/SAM binding site; other site
1081093010129	HemN C-terminal domain; Region: HemN_C; pfam06969
1081093010130	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1081093010131	G1 box; other site
1081093010132	GTP/Mg2+ binding site [chemical binding]; other site
1081093010133	Switch I region; other site
1081093010134	G2 box; other site
1081093010135	G3 box; other site
1081093010136	Switch II region; other site
1081093010137	G4 box; other site
1081093010138	G5 box; other site
1081093010139	DNA polymerase I; Provisional; Region: PRK05755
1081093010140	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1081093010141	active site
1081093010142	metal binding site 1 [ion binding]; metal-binding site
1081093010143	putative 5' ssDNA interaction site; other site
1081093010144	metal binding site 3; metal-binding site
1081093010145	metal binding site 2 [ion binding]; metal-binding site
1081093010146	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1081093010147	putative DNA binding site [nucleotide binding]; other site
1081093010148	putative metal binding site [ion binding]; other site
1081093010149	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1081093010150	active site
1081093010151	catalytic site [active]
1081093010152	substrate binding site [chemical binding]; other site
1081093010153	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1081093010154	active site
1081093010155	DNA binding site [nucleotide binding]
1081093010156	catalytic site [active]
1081093010157	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1081093010158	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1081093010159	putative acyl-acceptor binding pocket; other site
1081093010160	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1081093010161	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1081093010162	catalytic residues [active]
1081093010163	hinge region; other site
1081093010164	alpha helical domain; other site
1081093010165	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1081093010166	serine/threonine protein kinase; Provisional; Region: PRK11768
1081093010167	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1081093010168	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1081093010169	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1081093010170	GTP binding site; other site
1081093010171	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1081093010172	Walker A motif; other site
1081093010173	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1081093010174	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093010175	DNA-binding site [nucleotide binding]; DNA binding site
1081093010176	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1081093010177	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093010178	transcriptional repressor RbsR; Provisional; Region: PRK10423
1081093010179	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093010180	DNA binding site [nucleotide binding]
1081093010181	domain linker motif; other site
1081093010182	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1081093010183	dimerization interface [polypeptide binding]; other site
1081093010184	ligand binding site [chemical binding]; other site
1081093010185	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093010186	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1081093010187	substrate binding site [chemical binding]; other site
1081093010188	dimer interface [polypeptide binding]; other site
1081093010189	ATP binding site [chemical binding]; other site
1081093010190	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1081093010191	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1081093010192	ligand binding site [chemical binding]; other site
1081093010193	dimerization interface [polypeptide binding]; other site
1081093010194	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1081093010195	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1081093010196	TM-ABC transporter signature motif; other site
1081093010197	D-ribose pyranase; Provisional; Region: PRK11797
1081093010198	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1081093010199	potassium uptake protein; Region: kup; TIGR00794
1081093010200	regulatory ATPase RavA; Provisional; Region: PRK13531
1081093010201	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093010202	Walker A motif; other site
1081093010203	ATP binding site [chemical binding]; other site
1081093010204	Walker B motif; other site
1081093010205	arginine finger; other site
1081093010206	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1081093010207	hypothetical protein; Provisional; Region: yieM; PRK10997
1081093010208	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1081093010209	metal ion-dependent adhesion site (MIDAS); other site
1081093010210	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1081093010211	dimer interface [polypeptide binding]; other site
1081093010212	active site
1081093010213	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1081093010214	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1081093010215	putative DNA binding site [nucleotide binding]; other site
1081093010216	putative Zn2+ binding site [ion binding]; other site
1081093010217	AsnC family; Region: AsnC_trans_reg; pfam01037
1081093010218	FMN-binding protein MioC; Provisional; Region: PRK09004
1081093010219	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1081093010220	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1081093010221	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1081093010222	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1081093010223	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093010224	S-adenosylmethionine binding site [chemical binding]; other site
1081093010225	ATP synthase I chain; Region: ATP_synt_I; cl09170
1081093010226	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1081093010227	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1081093010228	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1081093010229	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1081093010230	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1081093010231	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1081093010232	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1081093010233	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1081093010234	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1081093010235	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1081093010236	beta subunit interaction interface [polypeptide binding]; other site
1081093010237	Walker A motif; other site
1081093010238	ATP binding site [chemical binding]; other site
1081093010239	Walker B motif; other site
1081093010240	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1081093010241	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1081093010242	core domain interface [polypeptide binding]; other site
1081093010243	delta subunit interface [polypeptide binding]; other site
1081093010244	epsilon subunit interface [polypeptide binding]; other site
1081093010245	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1081093010246	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1081093010247	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1081093010248	alpha subunit interaction interface [polypeptide binding]; other site
1081093010249	Walker A motif; other site
1081093010250	ATP binding site [chemical binding]; other site
1081093010251	Walker B motif; other site
1081093010252	inhibitor binding site; inhibition site
1081093010253	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1081093010254	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1081093010255	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1081093010256	gamma subunit interface [polypeptide binding]; other site
1081093010257	epsilon subunit interface [polypeptide binding]; other site
1081093010258	LBP interface [polypeptide binding]; other site
1081093010259	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1081093010260	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
1081093010261	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1081093010262	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1081093010263	Substrate binding site; other site
1081093010264	Mg++ binding site; other site
1081093010265	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1081093010266	active site
1081093010267	substrate binding site [chemical binding]; other site
1081093010268	CoA binding site [chemical binding]; other site
1081093010269	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1081093010270	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1081093010271	glutaminase active site [active]
1081093010272	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1081093010273	dimer interface [polypeptide binding]; other site
1081093010274	active site
1081093010275	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1081093010276	dimer interface [polypeptide binding]; other site
1081093010277	active site
1081093010278	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1081093010279	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1081093010280	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1081093010281	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
1081093010282	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1081093010283	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1081093010284	shikimate binding site; other site
1081093010285	NAD(P) binding site [chemical binding]; other site
1081093010286	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1081093010287	active site
1081093010288	P-loop; other site
1081093010289	phosphorylation site [posttranslational modification]
1081093010290	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1081093010291	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1081093010292	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093010293	substrate binding pocket [chemical binding]; other site
1081093010294	membrane-bound complex binding site; other site
1081093010295	hinge residues; other site
1081093010296	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1081093010297	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093010298	dimer interface [polypeptide binding]; other site
1081093010299	conserved gate region; other site
1081093010300	putative PBP binding loops; other site
1081093010301	ABC-ATPase subunit interface; other site
1081093010302	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1081093010303	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093010304	dimer interface [polypeptide binding]; other site
1081093010305	conserved gate region; other site
1081093010306	putative PBP binding loops; other site
1081093010307	ABC-ATPase subunit interface; other site
1081093010308	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1081093010309	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1081093010310	Walker A/P-loop; other site
1081093010311	ATP binding site [chemical binding]; other site
1081093010312	Q-loop/lid; other site
1081093010313	ABC transporter signature motif; other site
1081093010314	Walker B; other site
1081093010315	D-loop; other site
1081093010316	H-loop/switch region; other site
1081093010317	transcriptional regulator PhoU; Provisional; Region: PRK11115
1081093010318	PhoU domain; Region: PhoU; pfam01895
1081093010319	PhoU domain; Region: PhoU; pfam01895
1081093010320	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1081093010321	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093010322	active site
1081093010323	motif I; other site
1081093010324	motif II; other site
1081093010325	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1081093010326	Predicted flavoprotein [General function prediction only]; Region: COG0431
1081093010327	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1081093010328	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1081093010329	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1081093010330	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093010331	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1081093010332	substrate binding pocket [chemical binding]; other site
1081093010333	dimerization interface [polypeptide binding]; other site
1081093010334	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1081093010335	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093010336	putative substrate translocation pore; other site
1081093010337	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1081093010338	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1081093010339	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1081093010340	G1 box; other site
1081093010341	GTP/Mg2+ binding site [chemical binding]; other site
1081093010342	Switch I region; other site
1081093010343	G2 box; other site
1081093010344	Switch II region; other site
1081093010345	G3 box; other site
1081093010346	G4 box; other site
1081093010347	G5 box; other site
1081093010348	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1081093010349	membrane protein insertase; Provisional; Region: PRK01318
1081093010350	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
1081093010351	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1081093010352	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1081093010353	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1081093010354	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1081093010355	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1081093010356	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093010357	Walker A motif; other site
1081093010358	ATP binding site [chemical binding]; other site
1081093010359	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1081093010360	Walker B motif; other site
1081093010361	arginine finger; other site
1081093010362	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1081093010363	DnaA box-binding interface [nucleotide binding]; other site
1081093010364	DNA polymerase III subunit beta; Validated; Region: PRK05643
1081093010365	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1081093010366	putative DNA binding surface [nucleotide binding]; other site
1081093010367	dimer interface [polypeptide binding]; other site
1081093010368	beta-clamp/clamp loader binding surface; other site
1081093010369	beta-clamp/translesion DNA polymerase binding surface; other site
1081093010370	recF protein; Region: recf; TIGR00611
1081093010371	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093010372	Walker A/P-loop; other site
1081093010373	ATP binding site [chemical binding]; other site
1081093010374	Q-loop/lid; other site
1081093010375	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093010376	ABC transporter signature motif; other site
1081093010377	Walker B; other site
1081093010378	D-loop; other site
1081093010379	H-loop/switch region; other site
1081093010380	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1081093010381	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093010382	Mg2+ binding site [ion binding]; other site
1081093010383	G-X-G motif; other site
1081093010384	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1081093010385	anchoring element; other site
1081093010386	dimer interface [polypeptide binding]; other site
1081093010387	ATP binding site [chemical binding]; other site
1081093010388	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1081093010389	active site
1081093010390	putative metal-binding site [ion binding]; other site
1081093010391	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1081093010392	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093010393	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093010394	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1081093010395	putative dimerization interface [polypeptide binding]; other site
1081093010396	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1081093010397	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1081093010398	active site pocket [active]
1081093010399	sugar phosphate phosphatase; Provisional; Region: PRK10513
1081093010400	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093010401	active site
1081093010402	motif I; other site
1081093010403	motif II; other site
1081093010404	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093010405	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1081093010406	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093010407	DNA-binding site [nucleotide binding]; DNA binding site
1081093010408	FCD domain; Region: FCD; pfam07729
1081093010409	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
1081093010410	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
1081093010411	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
1081093010412	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1081093010413	active site
1081093010414	intersubunit interface [polypeptide binding]; other site
1081093010415	catalytic residue [active]
1081093010416	galactonate dehydratase; Provisional; Region: PRK14017
1081093010417	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
1081093010418	putative active site pocket [active]
1081093010419	putative metal binding site [ion binding]; other site
1081093010420	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093010421	D-galactonate transporter; Region: 2A0114; TIGR00893
1081093010422	putative substrate translocation pore; other site
1081093010423	chaperone protein TorD; Validated; Region: torD; PRK04976
1081093010424	Haem-binding domain; Region: Haem_bd; pfam14376
1081093010425	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1081093010426	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093010427	Walker A/P-loop; other site
1081093010428	ATP binding site [chemical binding]; other site
1081093010429	Q-loop/lid; other site
1081093010430	ABC transporter signature motif; other site
1081093010431	Walker B; other site
1081093010432	D-loop; other site
1081093010433	H-loop/switch region; other site
1081093010434	heme exporter protein CcmB; Region: ccmB; TIGR01190
1081093010435	heme exporter protein CcmC; Region: ccmC; TIGR01191
1081093010436	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1081093010437	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1081093010438	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1081093010439	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1081093010440	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1081093010441	catalytic residues [active]
1081093010442	central insert; other site
1081093010443	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1081093010444	hypothetical protein; Provisional; Region: PRK11616
1081093010445	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1081093010446	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1081093010447	putative dimer interface [polypeptide binding]; other site
1081093010448	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1081093010449	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1081093010450	putative dimer interface [polypeptide binding]; other site
1081093010451	putative transporter; Validated; Region: PRK03818
1081093010452	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1081093010453	TrkA-C domain; Region: TrkA_C; pfam02080
1081093010454	TrkA-C domain; Region: TrkA_C; pfam02080
1081093010455	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1081093010456	Predicted membrane protein [Function unknown]; Region: COG2149
1081093010457	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1081093010458	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
1081093010459	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
1081093010460	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1081093010461	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1081093010462	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1081093010463	catalytic residue [active]
1081093010464	permease DsdX; Provisional; Region: PRK09921
1081093010465	gluconate transporter; Region: gntP; TIGR00791
1081093010466	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
1081093010467	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093010468	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1081093010469	dimerization interface [polypeptide binding]; other site
1081093010470	substrate binding pocket [chemical binding]; other site
1081093010471	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1081093010472	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093010473	putative substrate translocation pore; other site
1081093010474	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1081093010475	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1081093010476	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1081093010477	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1081093010478	PYR/PP interface [polypeptide binding]; other site
1081093010479	dimer interface [polypeptide binding]; other site
1081093010480	TPP binding site [chemical binding]; other site
1081093010481	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1081093010482	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1081093010483	TPP-binding site [chemical binding]; other site
1081093010484	dimer interface [polypeptide binding]; other site
1081093010485	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1081093010486	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1081093010487	putative valine binding site [chemical binding]; other site
1081093010488	dimer interface [polypeptide binding]; other site
1081093010489	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1081093010490	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1081093010491	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093010492	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093010493	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1081093010494	substrate binding site [chemical binding]; other site
1081093010495	dimer interface [polypeptide binding]; other site
1081093010496	ATP binding site [chemical binding]; other site
1081093010497	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1081093010498	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093010499	putative substrate translocation pore; other site
1081093010500	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1081093010501	active site
1081093010502	catalytic residues [active]
1081093010503	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1081093010504	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093010505	active site
1081093010506	phosphorylation site [posttranslational modification]
1081093010507	intermolecular recognition site; other site
1081093010508	dimerization interface [polypeptide binding]; other site
1081093010509	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093010510	DNA binding residues [nucleotide binding]
1081093010511	dimerization interface [polypeptide binding]; other site
1081093010512	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1081093010513	MASE1; Region: MASE1; pfam05231
1081093010514	Histidine kinase; Region: HisKA_3; pfam07730
1081093010515	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093010516	ATP binding site [chemical binding]; other site
1081093010517	Mg2+ binding site [ion binding]; other site
1081093010518	G-X-G motif; other site
1081093010519	regulatory protein UhpC; Provisional; Region: PRK11663
1081093010520	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093010521	putative substrate translocation pore; other site
1081093010522	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1081093010523	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093010524	putative substrate translocation pore; other site
1081093010525	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1081093010526	Predicted transcriptional regulator [Transcription]; Region: COG2944
1081093010527	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093010528	non-specific DNA binding site [nucleotide binding]; other site
1081093010529	salt bridge; other site
1081093010530	sequence-specific DNA binding site [nucleotide binding]; other site
1081093010531	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
1081093010532	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1081093010533	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093010534	putative substrate translocation pore; other site
1081093010535	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1081093010536	beta-galactosidase; Region: BGL; TIGR03356
1081093010537	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1081093010538	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093010539	Walker A motif; other site
1081093010540	ATP binding site [chemical binding]; other site
1081093010541	Walker B motif; other site
1081093010542	arginine finger; other site
1081093010543	Transcriptional antiterminator [Transcription]; Region: COG3933
1081093010544	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1081093010545	active site
1081093010546	active pocket/dimerization site; other site
1081093010547	phosphorylation site [posttranslational modification]
1081093010548	PRD domain; Region: PRD; pfam00874
1081093010549	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1081093010550	active pocket/dimerization site; other site
1081093010551	active site
1081093010552	phosphorylation site [posttranslational modification]
1081093010553	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1081093010554	active site
1081093010555	phosphorylation site [posttranslational modification]
1081093010556	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1081093010557	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1081093010558	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1081093010559	hypothetical protein; Provisional; Region: PRK09956
1081093010560	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1081093010561	EamA-like transporter family; Region: EamA; pfam00892
1081093010562	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1081093010563	EamA-like transporter family; Region: EamA; pfam00892
1081093010564	magnesium transport protein MgtC; Provisional; Region: PRK15385
1081093010565	MgtC family; Region: MgtC; pfam02308
1081093010566	magnesium-transporting ATPase; Provisional; Region: PRK15122
1081093010567	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1081093010568	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1081093010569	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1081093010570	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093010571	motif II; other site
1081093010572	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1081093010573	Isochorismatase family; Region: Isochorismatase; pfam00857
1081093010574	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1081093010575	catalytic triad [active]
1081093010576	dimer interface [polypeptide binding]; other site
1081093010577	conserved cis-peptide bond; other site
1081093010578	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1081093010579	DNA binding site [nucleotide binding]
1081093010580	autotransport protein MisL; Provisional; Region: PRK15313
1081093010581	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1081093010582	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1081093010583	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1081093010584	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1081093010585	Transposase; Region: HTH_Tnp_1; pfam01527
1081093010586	Virulence protein [General function prediction only]; Region: COG3943
1081093010587	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1081093010588	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1081093010589	putative alpha-glucosidase; Provisional; Region: PRK10658
1081093010590	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1081093010591	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1081093010592	active site
1081093010593	homotrimer interface [polypeptide binding]; other site
1081093010594	catalytic site [active]
1081093010595	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1081093010596	AsmA family; Region: AsmA; pfam05170
1081093010597	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1081093010598	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1081093010599	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1081093010600	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1081093010601	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1081093010602	generic binding surface II; other site
1081093010603	ssDNA binding site; other site
1081093010604	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1081093010605	ATP binding site [chemical binding]; other site
1081093010606	putative Mg++ binding site [ion binding]; other site
1081093010607	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1081093010608	nucleotide binding region [chemical binding]; other site
1081093010609	ATP-binding site [chemical binding]; other site
1081093010610	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1081093010611	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1081093010612	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1081093010613	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1081093010614	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1081093010615	Zn2+ binding site [ion binding]; other site
1081093010616	Mg2+ binding site [ion binding]; other site
1081093010617	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1081093010618	synthetase active site [active]
1081093010619	NTP binding site [chemical binding]; other site
1081093010620	metal binding site [ion binding]; metal-binding site
1081093010621	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1081093010622	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1081093010623	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1081093010624	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1081093010625	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1081093010626	catalytic site [active]
1081093010627	G-X2-G-X-G-K; other site
1081093010628	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1081093010629	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1081093010630	nucleotide binding pocket [chemical binding]; other site
1081093010631	K-X-D-G motif; other site
1081093010632	catalytic site [active]
1081093010633	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1081093010634	Predicted membrane protein [Function unknown]; Region: COG2860
1081093010635	UPF0126 domain; Region: UPF0126; pfam03458
1081093010636	UPF0126 domain; Region: UPF0126; pfam03458
1081093010637	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1081093010638	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093010639	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093010640	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1081093010641	dimerization interface [polypeptide binding]; other site
1081093010642	hypothetical protein; Provisional; Region: PRK11820
1081093010643	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1081093010644	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1081093010645	ribonuclease PH; Reviewed; Region: rph; PRK00173
1081093010646	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1081093010647	hexamer interface [polypeptide binding]; other site
1081093010648	active site
1081093010649	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1081093010650	active site
1081093010651	division inhibitor protein; Provisional; Region: slmA; PRK09480
1081093010652	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093010653	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1081093010654	trimer interface [polypeptide binding]; other site
1081093010655	active site
1081093010656	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1081093010657	Flavoprotein; Region: Flavoprotein; pfam02441
1081093010658	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1081093010659	hypothetical protein; Reviewed; Region: PRK00024
1081093010660	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1081093010661	MPN+ (JAMM) motif; other site
1081093010662	Zinc-binding site [ion binding]; other site
1081093010663	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1081093010664	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1081093010665	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1081093010666	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1081093010667	DNA binding site [nucleotide binding]
1081093010668	catalytic residue [active]
1081093010669	H2TH interface [polypeptide binding]; other site
1081093010670	putative catalytic residues [active]
1081093010671	turnover-facilitating residue; other site
1081093010672	intercalation triad [nucleotide binding]; other site
1081093010673	8OG recognition residue [nucleotide binding]; other site
1081093010674	putative reading head residues; other site
1081093010675	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1081093010676	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1081093010677	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1081093010678	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1081093010679	active site
1081093010680	(T/H)XGH motif; other site
1081093010681	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
1081093010682	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1081093010683	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1081093010684	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1081093010685	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1081093010686	putative active site [active]
1081093010687	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1081093010688	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1081093010689	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1081093010690	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1081093010691	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
1081093010692	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1081093010693	putative ADP-binding pocket [chemical binding]; other site
1081093010694	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1081093010695	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1081093010696	Ligand binding site; other site
1081093010697	metal-binding site
1081093010698	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1081093010699	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
1081093010700	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1081093010701	Ligand binding site; other site
1081093010702	metal-binding site
1081093010703	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1081093010704	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
1081093010705	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
1081093010706	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
1081093010707	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1081093010708	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1081093010709	O-antigen ligase RfaL; Provisional; Region: PRK15487
1081093010710	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1081093010711	Glycosyltransferase family 9 (heptosyltransferase); Region: Glyco_transf_9; pfam01075
1081093010712	putative active site [active]
1081093010713	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1081093010714	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1081093010715	putative active site [active]
1081093010716	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1081093010717	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1081093010718	NADP binding site [chemical binding]; other site
1081093010719	homopentamer interface [polypeptide binding]; other site
1081093010720	substrate binding site [chemical binding]; other site
1081093010721	active site
1081093010722	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1081093010723	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1081093010724	substrate-cofactor binding pocket; other site
1081093010725	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093010726	catalytic residue [active]
1081093010727	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1081093010728	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1081093010729	NAD(P) binding site [chemical binding]; other site
1081093010730	putative glycosyl transferase; Provisional; Region: PRK10073
1081093010731	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1081093010732	active site
1081093010733	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1081093010734	NodB motif; other site
1081093010735	putative active site [active]
1081093010736	putative catalytic site [active]
1081093010737	Zn binding site [ion binding]; other site
1081093010738	AmiB activator; Provisional; Region: PRK11637
1081093010739	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1081093010740	Peptidase family M23; Region: Peptidase_M23; pfam01551
1081093010741	phosphoglyceromutase; Provisional; Region: PRK05434
1081093010742	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1081093010743	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1081093010744	active site residue [active]
1081093010745	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1081093010746	GSH binding site [chemical binding]; other site
1081093010747	catalytic residues [active]
1081093010748	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1081093010749	SecA binding site; other site
1081093010750	Preprotein binding site; other site
1081093010751	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1081093010752	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1081093010753	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1081093010754	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1081093010755	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1081093010756	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1081093010757	trimer interface [polypeptide binding]; other site
1081093010758	active site
1081093010759	substrate binding site [chemical binding]; other site
1081093010760	CoA binding site [chemical binding]; other site
1081093010761	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1081093010762	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1081093010763	active site pocket [active]
1081093010764	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1081093010765	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093010766	DNA binding site [nucleotide binding]
1081093010767	domain linker motif; other site
1081093010768	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1081093010769	putative dimerization interface [polypeptide binding]; other site
1081093010770	putative ligand binding site [chemical binding]; other site
1081093010771	putative rRNA methylase; Provisional; Region: PRK10358
1081093010772	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1081093010773	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1081093010774	active site
1081093010775	substrate binding site [chemical binding]; other site
1081093010776	FMN binding site [chemical binding]; other site
1081093010777	putative catalytic residues [active]
1081093010778	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1081093010779	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093010780	DNA-binding site [nucleotide binding]; DNA binding site
1081093010781	FCD domain; Region: FCD; pfam07729
1081093010782	L-lactate permease; Provisional; Region: PRK10420
1081093010783	glycolate transporter; Provisional; Region: PRK09695
1081093010784	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
1081093010785	trimer interface [polypeptide binding]; other site
1081093010786	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
1081093010787	Haemagglutinin; Region: HIM; pfam05662
1081093010788	Haemagglutinin; Region: HIM; pfam05662
1081093010789	YadA-like C-terminal region; Region: YadA; pfam03895
1081093010790	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
1081093010791	hypothetical protein; Provisional; Region: PRK11020
1081093010792	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1081093010793	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1081093010794	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1081093010795	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1081093010796	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1081093010797	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1081093010798	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1081093010799	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1081093010800	active site
1081093010801	P-loop; other site
1081093010802	phosphorylation site [posttranslational modification]
1081093010803	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1081093010804	active site
1081093010805	phosphorylation site [posttranslational modification]
1081093010806	putative glutathione S-transferase; Provisional; Region: PRK10357
1081093010807	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1081093010808	putative C-terminal domain interface [polypeptide binding]; other site
1081093010809	putative GSH binding site (G-site) [chemical binding]; other site
1081093010810	putative dimer interface [polypeptide binding]; other site
1081093010811	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1081093010812	dimer interface [polypeptide binding]; other site
1081093010813	N-terminal domain interface [polypeptide binding]; other site
1081093010814	putative substrate binding pocket (H-site) [chemical binding]; other site
1081093010815	selenocysteine synthase; Provisional; Region: PRK04311
1081093010816	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1081093010817	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1081093010818	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1081093010819	catalytic residue [active]
1081093010820	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1081093010821	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1081093010822	G1 box; other site
1081093010823	putative GEF interaction site [polypeptide binding]; other site
1081093010824	GTP/Mg2+ binding site [chemical binding]; other site
1081093010825	Switch I region; other site
1081093010826	G2 box; other site
1081093010827	G3 box; other site
1081093010828	Switch II region; other site
1081093010829	G4 box; other site
1081093010830	G5 box; other site
1081093010831	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1081093010832	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1081093010833	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1081093010834	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1081093010835	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1081093010836	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1081093010837	nucleotide binding site [chemical binding]; other site
1081093010838	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1081093010839	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1081093010840	NAD(P) binding site [chemical binding]; other site
1081093010841	catalytic residues [active]
1081093010842	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1081093010843	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1081093010844	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1081093010845	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1081093010846	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093010847	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1081093010848	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1081093010849	intersubunit interface [polypeptide binding]; other site
1081093010850	active site
1081093010851	Zn2+ binding site [ion binding]; other site
1081093010852	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1081093010853	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1081093010854	AP (apurinic/apyrimidinic) site pocket; other site
1081093010855	DNA interaction; other site
1081093010856	Metal-binding active site; metal-binding site
1081093010857	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1081093010858	active site
1081093010859	dimer interface [polypeptide binding]; other site
1081093010860	magnesium binding site [ion binding]; other site
1081093010861	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1081093010862	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1081093010863	putative N- and C-terminal domain interface [polypeptide binding]; other site
1081093010864	putative active site [active]
1081093010865	MgATP binding site [chemical binding]; other site
1081093010866	catalytic site [active]
1081093010867	metal binding site [ion binding]; metal-binding site
1081093010868	putative xylulose binding site [chemical binding]; other site
1081093010869	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1081093010870	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1081093010871	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
1081093010872	DctM-like transporters; Region: DctM; pfam06808
1081093010873	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
1081093010874	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1081093010875	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1081093010876	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1081093010877	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1081093010878	Bacterial transcriptional regulator; Region: IclR; pfam01614
1081093010879	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1081093010880	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1081093010881	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093010882	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093010883	homodimer interface [polypeptide binding]; other site
1081093010884	catalytic residue [active]
1081093010885	alpha-amylase; Reviewed; Region: malS; PRK09505
1081093010886	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1081093010887	active site
1081093010888	catalytic site [active]
1081093010889	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1081093010890	hypothetical protein; Provisional; Region: PRK10356
1081093010891	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1081093010892	putative dimerization interface [polypeptide binding]; other site
1081093010893	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1081093010894	putative ligand binding site [chemical binding]; other site
1081093010895	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093010896	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1081093010897	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093010898	xylose isomerase; Provisional; Region: PRK05474
1081093010899	xylose isomerase; Region: xylose_isom_A; TIGR02630
1081093010900	xylulokinase; Provisional; Region: PRK15027
1081093010901	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1081093010902	N- and C-terminal domain interface [polypeptide binding]; other site
1081093010903	active site
1081093010904	MgATP binding site [chemical binding]; other site
1081093010905	catalytic site [active]
1081093010906	metal binding site [ion binding]; metal-binding site
1081093010907	xylulose binding site [chemical binding]; other site
1081093010908	homodimer interface [polypeptide binding]; other site
1081093010909	Predicted membrane protein [Function unknown]; Region: COG4682
1081093010910	yiaA/B two helix domain; Region: YiaAB; cl01759
1081093010911	yiaA/B two helix domain; Region: YiaAB; cl01759
1081093010912	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1081093010913	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1081093010914	YsaB-like lipoprotein; Region: YsaB; pfam13983
1081093010915	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1081093010916	dimer interface [polypeptide binding]; other site
1081093010917	motif 1; other site
1081093010918	active site
1081093010919	motif 2; other site
1081093010920	motif 3; other site
1081093010921	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1081093010922	DALR anticodon binding domain; Region: DALR_1; pfam05746
1081093010923	Integrase core domain; Region: rve; pfam00665
1081093010924	Integrase core domain; Region: rve; pfam00665
1081093010925	Integrase core domain; Region: rve_2; pfam13333
1081093010926	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1081093010927	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1081093010928	DNA-binding site [nucleotide binding]; DNA binding site
1081093010929	RNA-binding motif; other site
1081093010930	Predicted transcriptional regulator [Transcription]; Region: COG2944
1081093010931	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093010932	salt bridge; other site
1081093010933	non-specific DNA binding site [nucleotide binding]; other site
1081093010934	sequence-specific DNA binding site [nucleotide binding]; other site
1081093010935	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1081093010936	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1081093010937	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1081093010938	dimerization interface [polypeptide binding]; other site
1081093010939	ligand binding site [chemical binding]; other site
1081093010940	NADP binding site [chemical binding]; other site
1081093010941	catalytic site [active]
1081093010942	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1081093010943	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1081093010944	ligand binding site [chemical binding]; other site
1081093010945	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1081093010946	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1081093010947	molybdopterin cofactor binding site [chemical binding]; other site
1081093010948	substrate binding site [chemical binding]; other site
1081093010949	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1081093010950	molybdopterin cofactor binding site; other site
1081093010951	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093010952	Coenzyme A binding pocket [chemical binding]; other site
1081093010953	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1081093010954	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1081093010955	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
1081093010956	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
1081093010957	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1081093010958	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1081093010959	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
1081093010960	phosphoethanolamine transferase; Provisional; Region: PRK11560
1081093010961	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1081093010962	Sulfatase; Region: Sulfatase; pfam00884
1081093010963	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1081093010964	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093010965	DNA binding site [nucleotide binding]
1081093010966	domain linker motif; other site
1081093010967	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
1081093010968	putative dimerization interface [polypeptide binding]; other site
1081093010969	putative ligand binding site [chemical binding]; other site
1081093010970	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
1081093010971	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1081093010972	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1081093010973	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1081093010974	peptide binding site [polypeptide binding]; other site
1081093010975	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1081093010976	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093010977	dimer interface [polypeptide binding]; other site
1081093010978	conserved gate region; other site
1081093010979	putative PBP binding loops; other site
1081093010980	ABC-ATPase subunit interface; other site
1081093010981	dipeptide transporter; Provisional; Region: PRK10913
1081093010982	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1081093010983	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093010984	dimer interface [polypeptide binding]; other site
1081093010985	conserved gate region; other site
1081093010986	putative PBP binding loops; other site
1081093010987	ABC-ATPase subunit interface; other site
1081093010988	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1081093010989	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093010990	Walker A/P-loop; other site
1081093010991	ATP binding site [chemical binding]; other site
1081093010992	Q-loop/lid; other site
1081093010993	ABC transporter signature motif; other site
1081093010994	Walker B; other site
1081093010995	D-loop; other site
1081093010996	H-loop/switch region; other site
1081093010997	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1081093010998	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1081093010999	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1081093011000	Walker A/P-loop; other site
1081093011001	ATP binding site [chemical binding]; other site
1081093011002	Q-loop/lid; other site
1081093011003	ABC transporter signature motif; other site
1081093011004	Walker B; other site
1081093011005	D-loop; other site
1081093011006	H-loop/switch region; other site
1081093011007	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1081093011008	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1081093011009	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1081093011010	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1081093011011	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1081093011012	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1081093011013	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
1081093011014	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
1081093011015	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1081093011016	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1081093011017	cell division protein; Provisional; Region: PRK10037
1081093011018	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1081093011019	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1081093011020	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1081093011021	DXD motif; other site
1081093011022	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1081093011023	PilZ domain; Region: PilZ; pfam07238
1081093011024	cellulose synthase regulator protein; Provisional; Region: PRK11114
1081093011025	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1081093011026	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1081093011027	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1081093011028	TPR motif; other site
1081093011029	binding surface
1081093011030	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1081093011031	TPR motif; other site
1081093011032	binding surface
1081093011033	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1081093011034	binding surface
1081093011035	TPR motif; other site
1081093011036	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1081093011037	putative diguanylate cyclase; Provisional; Region: PRK13561
1081093011038	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093011039	metal binding site [ion binding]; metal-binding site
1081093011040	active site
1081093011041	I-site; other site
1081093011042	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093011043	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1081093011044	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1081093011045	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1081093011046	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1081093011047	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093011048	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1081093011049	substrate binding site [chemical binding]; other site
1081093011050	ATP binding site [chemical binding]; other site
1081093011051	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1081093011052	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1081093011053	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093011054	metabolite-proton symporter; Region: 2A0106; TIGR00883
1081093011055	putative substrate translocation pore; other site
1081093011056	inner membrane protein YhjD; Region: TIGR00766
1081093011057	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093011058	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093011059	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1081093011060	putative effector binding pocket; other site
1081093011061	putative dimerization interface [polypeptide binding]; other site
1081093011062	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
1081093011063	catalytic residue [active]
1081093011064	trehalase; Provisional; Region: treF; PRK13270
1081093011065	Trehalase; Region: Trehalase; pfam01204
1081093011066	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1081093011067	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093011068	DNA-binding site [nucleotide binding]; DNA binding site
1081093011069	UTRA domain; Region: UTRA; pfam07702
1081093011070	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1081093011071	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1081093011072	putative active site [active]
1081093011073	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1081093011074	dimer interface [polypeptide binding]; other site
1081093011075	active site
1081093011076	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
1081093011077	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093011078	substrate binding site [chemical binding]; other site
1081093011079	ATP binding site [chemical binding]; other site
1081093011080	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1081093011081	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1081093011082	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1081093011083	active site
1081093011084	homodimer interface [polypeptide binding]; other site
1081093011085	homotetramer interface [polypeptide binding]; other site
1081093011086	glutathione reductase; Validated; Region: PRK06116
1081093011087	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1081093011088	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093011089	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1081093011090	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1081093011091	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1081093011092	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1081093011093	active site
1081093011094	oligopeptidase A; Provisional; Region: PRK10911
1081093011095	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1081093011096	active site
1081093011097	Zn binding site [ion binding]; other site
1081093011098	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093011099	S-adenosylmethionine binding site [chemical binding]; other site
1081093011100	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1081093011101	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093011102	putative substrate translocation pore; other site
1081093011103	POT family; Region: PTR2; pfam00854
1081093011104	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1081093011105	Ligand Binding Site [chemical binding]; other site
1081093011106	universal stress protein UspB; Provisional; Region: PRK04960
1081093011107	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1081093011108	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1081093011109	Predicted flavoproteins [General function prediction only]; Region: COG2081
1081093011110	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1081093011111	HlyD family secretion protein; Region: HlyD; pfam00529
1081093011112	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1081093011113	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093011114	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1081093011115	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1081093011116	nickel responsive regulator; Provisional; Region: PRK02967
1081093011117	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1081093011118	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1081093011119	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1081093011120	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1081093011121	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1081093011122	major facilitator superfamily transporter; Provisional; Region: PRK05122
1081093011123	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093011124	putative substrate translocation pore; other site
1081093011125	hypothetical protein; Provisional; Region: PRK11615
1081093011126	hypothetical protein; Provisional; Region: PRK11212
1081093011127	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1081093011128	CPxP  motif; other site
1081093011129	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1081093011130	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1081093011131	dimer interface [polypeptide binding]; other site
1081093011132	ligand binding site [chemical binding]; other site
1081093011133	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093011134	dimerization interface [polypeptide binding]; other site
1081093011135	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1081093011136	dimer interface [polypeptide binding]; other site
1081093011137	putative CheW interface [polypeptide binding]; other site
1081093011138	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1081093011139	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1081093011140	metal-binding site [ion binding]
1081093011141	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1081093011142	Predicted membrane protein [Function unknown]; Region: COG3714
1081093011143	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1081093011144	hypothetical protein; Provisional; Region: PRK10910
1081093011145	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1081093011146	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093011147	S-adenosylmethionine binding site [chemical binding]; other site
1081093011148	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1081093011149	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1081093011150	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1081093011151	P loop; other site
1081093011152	GTP binding site [chemical binding]; other site
1081093011153	cell division protein FtsE; Provisional; Region: PRK10908
1081093011154	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093011155	Walker A/P-loop; other site
1081093011156	ATP binding site [chemical binding]; other site
1081093011157	Q-loop/lid; other site
1081093011158	ABC transporter signature motif; other site
1081093011159	Walker B; other site
1081093011160	D-loop; other site
1081093011161	H-loop/switch region; other site
1081093011162	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1081093011163	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1081093011164	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1081093011165	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1081093011166	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1081093011167	DNA binding residues [nucleotide binding]
1081093011168	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1081093011169	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1081093011170	dimerization interface [polypeptide binding]; other site
1081093011171	ligand binding site [chemical binding]; other site
1081093011172	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1081093011173	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1081093011174	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1081093011175	dimerization interface [polypeptide binding]; other site
1081093011176	ligand binding site [chemical binding]; other site
1081093011177	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1081093011178	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1081093011179	TM-ABC transporter signature motif; other site
1081093011180	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1081093011181	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1081093011182	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1081093011183	TM-ABC transporter signature motif; other site
1081093011184	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1081093011185	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1081093011186	Walker A/P-loop; other site
1081093011187	ATP binding site [chemical binding]; other site
1081093011188	Q-loop/lid; other site
1081093011189	ABC transporter signature motif; other site
1081093011190	Walker B; other site
1081093011191	D-loop; other site
1081093011192	H-loop/switch region; other site
1081093011193	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1081093011194	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1081093011195	Walker A/P-loop; other site
1081093011196	ATP binding site [chemical binding]; other site
1081093011197	Q-loop/lid; other site
1081093011198	ABC transporter signature motif; other site
1081093011199	Walker B; other site
1081093011200	D-loop; other site
1081093011201	H-loop/switch region; other site
1081093011202	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1081093011203	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
1081093011204	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1081093011205	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1081093011206	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1081093011207	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093011208	dimer interface [polypeptide binding]; other site
1081093011209	conserved gate region; other site
1081093011210	putative PBP binding loops; other site
1081093011211	ABC-ATPase subunit interface; other site
1081093011212	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1081093011213	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093011214	dimer interface [polypeptide binding]; other site
1081093011215	conserved gate region; other site
1081093011216	ABC-ATPase subunit interface; other site
1081093011217	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1081093011218	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1081093011219	Walker A/P-loop; other site
1081093011220	ATP binding site [chemical binding]; other site
1081093011221	Q-loop/lid; other site
1081093011222	ABC transporter signature motif; other site
1081093011223	Walker B; other site
1081093011224	D-loop; other site
1081093011225	H-loop/switch region; other site
1081093011226	TOBE domain; Region: TOBE_2; pfam08402
1081093011227	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1081093011228	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1081093011229	putative active site [active]
1081093011230	catalytic site [active]
1081093011231	putative metal binding site [ion binding]; other site
1081093011232	hypothetical protein; Provisional; Region: PRK10350
1081093011233	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1081093011234	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1081093011235	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1081093011236	active site
1081093011237	substrate binding pocket [chemical binding]; other site
1081093011238	homodimer interaction site [polypeptide binding]; other site
1081093011239	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1081093011240	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1081093011241	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1081093011242	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093011243	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1081093011244	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1081093011245	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1081093011246	substrate binding site [chemical binding]; other site
1081093011247	dimer interface [polypeptide binding]; other site
1081093011248	ATP binding site [chemical binding]; other site
1081093011249	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1081093011250	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093011251	Coenzyme A binding pocket [chemical binding]; other site
1081093011252	putative oxidoreductase; Provisional; Region: PRK10206
1081093011253	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1081093011254	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1081093011255	Pirin-related protein [General function prediction only]; Region: COG1741
1081093011256	Pirin; Region: Pirin; pfam02678
1081093011257	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1081093011258	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093011259	DNA binding site [nucleotide binding]
1081093011260	domain linker motif; other site
1081093011261	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1081093011262	putative ligand binding site [chemical binding]; other site
1081093011263	putative dimerization interface [polypeptide binding]; other site
1081093011264	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1081093011265	low affinity gluconate transporter; Provisional; Region: PRK10472
1081093011266	gluconate transporter; Region: gntP; TIGR00791
1081093011267	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1081093011268	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1081093011269	glycogen debranching enzyme; Provisional; Region: PRK03705
1081093011270	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1081093011271	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1081093011272	active site
1081093011273	catalytic site [active]
1081093011274	glycogen synthase; Provisional; Region: glgA; PRK00654
1081093011275	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1081093011276	ADP-binding pocket [chemical binding]; other site
1081093011277	glycogen phosphorylase; Provisional; Region: PRK14986
1081093011278	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1081093011279	homodimer interface [polypeptide binding]; other site
1081093011280	active site pocket [active]
1081093011281	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1081093011282	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1081093011283	Bacterial transcriptional regulator; Region: IclR; pfam01614
1081093011284	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1081093011285	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1081093011286	inhibitor site; inhibition site
1081093011287	active site
1081093011288	dimer interface [polypeptide binding]; other site
1081093011289	catalytic residue [active]
1081093011290	Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism / Carbohydrate transport and metabolism]; Region: IlvD; COG0129
1081093011291	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093011292	D-galactonate transporter; Region: 2A0114; TIGR00893
1081093011293	putative substrate translocation pore; other site
1081093011294	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1081093011295	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1081093011296	dimer interface [polypeptide binding]; other site
1081093011297	active site
1081093011298	metal binding site [ion binding]; metal-binding site
1081093011299	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
1081093011300	hypothetical protein; Provisional; Region: PRK09781
1081093011301	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1081093011302	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1081093011303	active site residue [active]
1081093011304	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1081093011305	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1081093011306	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1081093011307	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1081093011308	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1081093011309	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093011310	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
1081093011311	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
1081093011312	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093011313	Walker A motif; other site
1081093011314	ATP binding site [chemical binding]; other site
1081093011315	Walker B motif; other site
1081093011316	arginine finger; other site
1081093011317	TROVE domain; Region: TROVE; pfam05731
1081093011318	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1081093011319	hypothetical protein; Reviewed; Region: PRK09588
1081093011320	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
1081093011321	RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine...; Region: RNA_Cyclase_Class_II; cd00874
1081093011322	putative active site [active]
1081093011323	adenylation catalytic residue [active]
1081093011324	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
1081093011325	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
1081093011326	transcriptional regulator MalT; Provisional; Region: PRK04841
1081093011327	AAA ATPase domain; Region: AAA_16; pfam13191
1081093011328	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093011329	DNA binding residues [nucleotide binding]
1081093011330	dimerization interface [polypeptide binding]; other site
1081093011331	maltodextrin phosphorylase; Provisional; Region: PRK14985
1081093011332	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1081093011333	homodimer interface [polypeptide binding]; other site
1081093011334	active site pocket [active]
1081093011335	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1081093011336	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
1081093011337	gluconate transporter; Region: gntP; TIGR00791
1081093011338	high-affinity gluconate transporter; Provisional; Region: PRK14984
1081093011339	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1081093011340	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1081093011341	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1081093011342	DNA utilization protein GntX; Provisional; Region: PRK11595
1081093011343	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1081093011344	active site
1081093011345	carboxylesterase BioH; Provisional; Region: PRK10349
1081093011346	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1081093011347	hypothetical protein; Provisional; Region: PRK09956
1081093011348	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1081093011349	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1081093011350	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1081093011351	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1081093011352	G1 box; other site
1081093011353	GTP/Mg2+ binding site [chemical binding]; other site
1081093011354	Switch I region; other site
1081093011355	G2 box; other site
1081093011356	G3 box; other site
1081093011357	Switch II region; other site
1081093011358	G4 box; other site
1081093011359	G5 box; other site
1081093011360	Nucleoside recognition; Region: Gate; pfam07670
1081093011361	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1081093011362	Nucleoside recognition; Region: Gate; pfam07670
1081093011363	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1081093011364	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1081093011365	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1081093011366	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1081093011367	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1081093011368	RNA binding site [nucleotide binding]; other site
1081093011369	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1081093011370	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1081093011371	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1081093011372	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1081093011373	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093011374	active site
1081093011375	phosphorylation site [posttranslational modification]
1081093011376	intermolecular recognition site; other site
1081093011377	dimerization interface [polypeptide binding]; other site
1081093011378	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093011379	DNA binding site [nucleotide binding]
1081093011380	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1081093011381	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093011382	dimerization interface [polypeptide binding]; other site
1081093011383	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093011384	dimer interface [polypeptide binding]; other site
1081093011385	phosphorylation site [posttranslational modification]
1081093011386	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093011387	ATP binding site [chemical binding]; other site
1081093011388	G-X-G motif; other site
1081093011389	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1081093011390	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1081093011391	active site
1081093011392	substrate-binding site [chemical binding]; other site
1081093011393	metal-binding site [ion binding]
1081093011394	ATP binding site [chemical binding]; other site
1081093011395	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1081093011396	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1081093011397	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1081093011398	dimerization interface [polypeptide binding]; other site
1081093011399	domain crossover interface; other site
1081093011400	redox-dependent activation switch; other site
1081093011401	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1081093011402	RNA binding surface [nucleotide binding]; other site
1081093011403	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1081093011404	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093011405	motif II; other site
1081093011406	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1081093011407	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1081093011408	ADP-ribose binding site [chemical binding]; other site
1081093011409	dimer interface [polypeptide binding]; other site
1081093011410	active site
1081093011411	nudix motif; other site
1081093011412	metal binding site [ion binding]; metal-binding site
1081093011413	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1081093011414	Transglycosylase; Region: Transgly; pfam00912
1081093011415	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1081093011416	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1081093011417	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1081093011418	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1081093011419	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
1081093011420	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1081093011421	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1081093011422	shikimate kinase; Reviewed; Region: aroK; PRK00131
1081093011423	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1081093011424	ADP binding site [chemical binding]; other site
1081093011425	magnesium binding site [ion binding]; other site
1081093011426	putative shikimate binding site; other site
1081093011427	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1081093011428	active site
1081093011429	dimer interface [polypeptide binding]; other site
1081093011430	metal binding site [ion binding]; metal-binding site
1081093011431	cell division protein DamX; Validated; Region: PRK10905
1081093011432	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
1081093011433	DNA adenine methylase; Provisional; Region: PRK10904
1081093011434	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1081093011435	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1081093011436	substrate binding site [chemical binding]; other site
1081093011437	hexamer interface [polypeptide binding]; other site
1081093011438	metal binding site [ion binding]; metal-binding site
1081093011439	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1081093011440	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093011441	motif II; other site
1081093011442	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1081093011443	active site
1081093011444	dimer interface [polypeptide binding]; other site
1081093011445	KMSKS motif; other site
1081093011446	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1081093011447	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1081093011448	siroheme synthase; Provisional; Region: cysG; PRK10637
1081093011449	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1081093011450	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1081093011451	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1081093011452	active site
1081093011453	SAM binding site [chemical binding]; other site
1081093011454	homodimer interface [polypeptide binding]; other site
1081093011455	nitrite transporter NirC; Provisional; Region: PRK11562
1081093011456	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1081093011457	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1081093011458	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1081093011459	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1081093011460	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1081093011461	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1081093011462	putative transporter; Provisional; Region: PRK03699
1081093011463	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093011464	putative substrate translocation pore; other site
1081093011465	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1081093011466	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1081093011467	substrate binding site [chemical binding]; other site
1081093011468	hypothetical protein; Provisional; Region: PRK10204
1081093011469	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1081093011470	cell filamentation protein Fic; Provisional; Region: PRK10347
1081093011471	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1081093011472	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1081093011473	glutamine binding [chemical binding]; other site
1081093011474	catalytic triad [active]
1081093011475	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1081093011476	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1081093011477	inhibitor-cofactor binding pocket; inhibition site
1081093011478	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093011479	catalytic residue [active]
1081093011480	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1081093011481	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1081093011482	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1081093011483	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1081093011484	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1081093011485	ligand binding site [chemical binding]; other site
1081093011486	flexible hinge region; other site
1081093011487	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1081093011488	putative switch regulator; other site
1081093011489	non-specific DNA interactions [nucleotide binding]; other site
1081093011490	DNA binding site [nucleotide binding]
1081093011491	sequence specific DNA binding site [nucleotide binding]; other site
1081093011492	putative cAMP binding site [chemical binding]; other site
1081093011493	hypothetical protein; Provisional; Region: PRK10738
1081093011494	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1081093011495	active site
1081093011496	hypothetical protein; Provisional; Region: PRK04966
1081093011497	putative hydrolase; Provisional; Region: PRK10985
1081093011498	putative monooxygenase; Provisional; Region: PRK11118
1081093011499	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1081093011500	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093011501	Walker A/P-loop; other site
1081093011502	ATP binding site [chemical binding]; other site
1081093011503	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093011504	ABC transporter signature motif; other site
1081093011505	Walker B; other site
1081093011506	D-loop; other site
1081093011507	ABC transporter; Region: ABC_tran_2; pfam12848
1081093011508	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093011509	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1081093011510	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1081093011511	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1081093011512	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1081093011513	phi X174 lysis protein; Provisional; Region: PRK02793
1081093011514	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1081093011515	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1081093011516	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1081093011517	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1081093011518	YheO-like PAS domain; Region: PAS_6; pfam08348
1081093011519	HTH domain; Region: HTH_22; pfam13309
1081093011520	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1081093011521	sulfur relay protein TusC; Validated; Region: PRK00211
1081093011522	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1081093011523	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1081093011524	S17 interaction site [polypeptide binding]; other site
1081093011525	S8 interaction site; other site
1081093011526	16S rRNA interaction site [nucleotide binding]; other site
1081093011527	streptomycin interaction site [chemical binding]; other site
1081093011528	23S rRNA interaction site [nucleotide binding]; other site
1081093011529	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1081093011530	30S ribosomal protein S7; Validated; Region: PRK05302
1081093011531	elongation factor G; Reviewed; Region: PRK00007
1081093011532	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1081093011533	G1 box; other site
1081093011534	putative GEF interaction site [polypeptide binding]; other site
1081093011535	GTP/Mg2+ binding site [chemical binding]; other site
1081093011536	Switch I region; other site
1081093011537	G2 box; other site
1081093011538	G3 box; other site
1081093011539	Switch II region; other site
1081093011540	G4 box; other site
1081093011541	G5 box; other site
1081093011542	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1081093011543	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1081093011544	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1081093011545	elongation factor Tu; Reviewed; Region: PRK00049
1081093011546	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1081093011547	G1 box; other site
1081093011548	GEF interaction site [polypeptide binding]; other site
1081093011549	GTP/Mg2+ binding site [chemical binding]; other site
1081093011550	Switch I region; other site
1081093011551	G2 box; other site
1081093011552	G3 box; other site
1081093011553	Switch II region; other site
1081093011554	G4 box; other site
1081093011555	G5 box; other site
1081093011556	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1081093011557	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1081093011558	Antibiotic Binding Site [chemical binding]; other site
1081093011559	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1081093011560	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1081093011561	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1081093011562	heme binding site [chemical binding]; other site
1081093011563	ferroxidase pore; other site
1081093011564	ferroxidase diiron center [ion binding]; other site
1081093011565	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1081093011566	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1081093011567	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1081093011568	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1081093011569	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1081093011570	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1081093011571	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1081093011572	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1081093011573	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1081093011574	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1081093011575	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1081093011576	protein-rRNA interface [nucleotide binding]; other site
1081093011577	putative translocon binding site; other site
1081093011578	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1081093011579	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1081093011580	G-X-X-G motif; other site
1081093011581	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1081093011582	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1081093011583	23S rRNA interface [nucleotide binding]; other site
1081093011584	5S rRNA interface [nucleotide binding]; other site
1081093011585	putative antibiotic binding site [chemical binding]; other site
1081093011586	L25 interface [polypeptide binding]; other site
1081093011587	L27 interface [polypeptide binding]; other site
1081093011588	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1081093011589	23S rRNA interface [nucleotide binding]; other site
1081093011590	putative translocon interaction site; other site
1081093011591	signal recognition particle (SRP54) interaction site; other site
1081093011592	L23 interface [polypeptide binding]; other site
1081093011593	trigger factor interaction site; other site
1081093011594	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1081093011595	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1081093011596	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1081093011597	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1081093011598	RNA binding site [nucleotide binding]; other site
1081093011599	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1081093011600	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1081093011601	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1081093011602	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1081093011603	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1081093011604	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1081093011605	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1081093011606	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1081093011607	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1081093011608	23S rRNA interface [nucleotide binding]; other site
1081093011609	5S rRNA interface [nucleotide binding]; other site
1081093011610	L27 interface [polypeptide binding]; other site
1081093011611	L5 interface [polypeptide binding]; other site
1081093011612	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1081093011613	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1081093011614	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1081093011615	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1081093011616	23S rRNA binding site [nucleotide binding]; other site
1081093011617	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1081093011618	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1081093011619	SecY translocase; Region: SecY; pfam00344
1081093011620	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1081093011621	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1081093011622	30S ribosomal protein S11; Validated; Region: PRK05309
1081093011623	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1081093011624	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1081093011625	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1081093011626	RNA binding surface [nucleotide binding]; other site
1081093011627	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1081093011628	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1081093011629	alphaNTD homodimer interface [polypeptide binding]; other site
1081093011630	alphaNTD - beta interaction site [polypeptide binding]; other site
1081093011631	alphaNTD - beta' interaction site [polypeptide binding]; other site
1081093011632	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1081093011633	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1081093011634	hypothetical protein; Provisional; Region: PRK10203
1081093011635	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1081093011636	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1081093011637	DNA binding residues [nucleotide binding]
1081093011638	dimer interface [polypeptide binding]; other site
1081093011639	metal binding site [ion binding]; metal-binding site
1081093011640	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1081093011641	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1081093011642	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1081093011643	TrkA-N domain; Region: TrkA_N; pfam02254
1081093011644	TrkA-C domain; Region: TrkA_C; pfam02080
1081093011645	TrkA-N domain; Region: TrkA_N; pfam02254
1081093011646	TrkA-C domain; Region: TrkA_C; pfam02080
1081093011647	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1081093011648	putative RNA binding site [nucleotide binding]; other site
1081093011649	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1081093011650	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093011651	S-adenosylmethionine binding site [chemical binding]; other site
1081093011652	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1081093011653	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1081093011654	putative active site [active]
1081093011655	substrate binding site [chemical binding]; other site
1081093011656	putative cosubstrate binding site; other site
1081093011657	catalytic site [active]
1081093011658	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1081093011659	substrate binding site [chemical binding]; other site
1081093011660	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1081093011661	active site
1081093011662	catalytic residues [active]
1081093011663	metal binding site [ion binding]; metal-binding site
1081093011664	hypothetical protein; Validated; Region: PRK03430
1081093011665	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1081093011666	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1081093011667	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1081093011668	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1081093011669	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1081093011670	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1081093011671	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1081093011672	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1081093011673	shikimate binding site; other site
1081093011674	NAD(P) binding site [chemical binding]; other site
1081093011675	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1081093011676	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1081093011677	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1081093011678	trimer interface [polypeptide binding]; other site
1081093011679	putative metal binding site [ion binding]; other site
1081093011680	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1081093011681	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093011682	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1081093011683	Coenzyme A binding pocket [chemical binding]; other site
1081093011684	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1081093011685	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1081093011686	proposed active site lysine [active]
1081093011687	conserved cys residue [active]
1081093011688	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1081093011689	malate synthase A; Region: malate_syn_A; TIGR01344
1081093011690	active site
1081093011691	isocitrate lyase; Provisional; Region: PRK15063
1081093011692	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1081093011693	tetramer interface [polypeptide binding]; other site
1081093011694	active site
1081093011695	Mg2+/Mn2+ binding site [ion binding]; other site
1081093011696	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1081093011697	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1081093011698	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1081093011699	transcriptional repressor IclR; Provisional; Region: PRK11569
1081093011700	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1081093011701	Bacterial transcriptional regulator; Region: IclR; pfam01614
1081093011702	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1081093011703	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1081093011704	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1081093011705	substrate binding pocket [chemical binding]; other site
1081093011706	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1081093011707	B12 binding site [chemical binding]; other site
1081093011708	cobalt ligand [ion binding]; other site
1081093011709	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1081093011710	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1081093011711	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1081093011712	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1081093011713	active site pocket [active]
1081093011714	oxyanion hole [active]
1081093011715	catalytic triad [active]
1081093011716	active site nucleophile [active]
1081093011717	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
1081093011718	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1081093011719	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1081093011720	RNA binding surface [nucleotide binding]; other site
1081093011721	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1081093011722	probable active site [active]
1081093011723	hypothetical protein; Provisional; Region: PRK10515
1081093011724	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1081093011725	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1081093011726	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093011727	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1081093011728	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093011729	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1081093011730	phosphate binding site [ion binding]; other site
1081093011731	Mor transcription activator family; Region: Mor; pfam08765
1081093011732	aspartate kinase III; Validated; Region: PRK09084
1081093011733	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1081093011734	nucleotide binding site [chemical binding]; other site
1081093011735	substrate binding site [chemical binding]; other site
1081093011736	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1081093011737	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1081093011738	dimer interface [polypeptide binding]; other site
1081093011739	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1081093011740	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1081093011741	active site
1081093011742	dimer interface [polypeptide binding]; other site
1081093011743	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1081093011744	dimer interface [polypeptide binding]; other site
1081093011745	active site
1081093011746	Exopolysaccharide production protein YjbE; Region: YjbE; pfam11106
1081093011747	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1081093011748	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1081093011749	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1081093011750	Predicted membrane protein [Function unknown]; Region: COG3223
1081093011751	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1081093011752	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1081093011753	dimer interface [polypeptide binding]; other site
1081093011754	conserved gate region; other site
1081093011755	putative PBP binding loops; other site
1081093011756	ABC-ATPase subunit interface; other site
1081093011757	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1081093011758	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1081093011759	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1081093011760	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1081093011761	Walker A/P-loop; other site
1081093011762	ATP binding site [chemical binding]; other site
1081093011763	Q-loop/lid; other site
1081093011764	ABC transporter signature motif; other site
1081093011765	Walker B; other site
1081093011766	D-loop; other site
1081093011767	H-loop/switch region; other site
1081093011768	TOBE domain; Region: TOBE_2; pfam08402
1081093011769	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1081093011770	trimer interface; other site
1081093011771	sugar binding site [chemical binding]; other site
1081093011772	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1081093011773	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1081093011774	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1081093011775	UbiA prenyltransferase family; Region: UbiA; pfam01040
1081093011776	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1081093011777	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1081093011778	putative acyl-acceptor binding pocket; other site
1081093011779	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1081093011780	LexA repressor; Validated; Region: PRK00215
1081093011781	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1081093011782	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1081093011783	Catalytic site [active]
1081093011784	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1081093011785	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1081093011786	hypothetical protein; Provisional; Region: PRK10428
1081093011787	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1081093011788	metal binding site 2 [ion binding]; metal-binding site
1081093011789	putative DNA binding helix; other site
1081093011790	metal binding site 1 [ion binding]; metal-binding site
1081093011791	dimer interface [polypeptide binding]; other site
1081093011792	structural Zn2+ binding site [ion binding]; other site
1081093011793	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1081093011794	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1081093011795	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1081093011796	FMN binding site [chemical binding]; other site
1081093011797	active site
1081093011798	catalytic residues [active]
1081093011799	substrate binding site [chemical binding]; other site
1081093011800	phage shock protein G; Reviewed; Region: pspG; PRK09459
1081093011801	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1081093011802	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1081093011803	NADP binding site [chemical binding]; other site
1081093011804	dimer interface [polypeptide binding]; other site
1081093011805	replicative DNA helicase; Provisional; Region: PRK08006
1081093011806	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1081093011807	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1081093011808	Walker A motif; other site
1081093011809	ATP binding site [chemical binding]; other site
1081093011810	Walker B motif; other site
1081093011811	DNA binding loops [nucleotide binding]
1081093011812	alanine racemase; Reviewed; Region: alr; PRK00053
1081093011813	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1081093011814	active site
1081093011815	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1081093011816	substrate binding site [chemical binding]; other site
1081093011817	catalytic residues [active]
1081093011818	dimer interface [polypeptide binding]; other site
1081093011819	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1081093011820	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1081093011821	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093011822	homodimer interface [polypeptide binding]; other site
1081093011823	catalytic residue [active]
1081093011824	acid phosphatase/phosphotransferase; Provisional; Region: aphA; PRK11009
1081093011825	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
1081093011826	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1081093011827	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1081093011828	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1081093011829	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1081093011830	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1081093011831	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1081093011832	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1081093011833	dimer interface [polypeptide binding]; other site
1081093011834	ssDNA binding site [nucleotide binding]; other site
1081093011835	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1081093011836	hypothetical protein; Validated; Region: PRK09039
1081093011837	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
1081093011838	Outer membrane efflux protein; Region: OEP; pfam02321
1081093011839	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1081093011840	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1081093011841	HlyD family secretion protein; Region: HlyD_3; pfam13437
1081093011842	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011843	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011844	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011845	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011846	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1081093011847	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1081093011848	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011849	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1081093011850	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011851	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1081093011852	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1081093011853	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011854	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1081093011855	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1081093011856	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011857	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1081093011858	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011859	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1081093011860	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1081093011861	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011862	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1081093011863	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1081093011864	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011865	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1081093011866	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011867	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011868	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1081093011869	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011870	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011871	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011872	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011873	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011874	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011875	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1081093011876	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011877	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
1081093011878	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011879	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011880	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1081093011881	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1081093011882	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1081093011883	Walker A/P-loop; other site
1081093011884	ATP binding site [chemical binding]; other site
1081093011885	Q-loop/lid; other site
1081093011886	ABC transporter signature motif; other site
1081093011887	Walker B; other site
1081093011888	D-loop; other site
1081093011889	H-loop/switch region; other site
1081093011890	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1081093011891	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1081093011892	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1081093011893	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1081093011894	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093011895	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1081093011896	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1081093011897	DNA binding residues [nucleotide binding]
1081093011898	dimer interface [polypeptide binding]; other site
1081093011899	[2Fe-2S] cluster binding site [ion binding]; other site
1081093011900	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1081093011901	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1081093011902	putative C-terminal domain interface [polypeptide binding]; other site
1081093011903	putative GSH binding site (G-site) [chemical binding]; other site
1081093011904	putative dimer interface [polypeptide binding]; other site
1081093011905	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1081093011906	putative N-terminal domain interface [polypeptide binding]; other site
1081093011907	putative dimer interface [polypeptide binding]; other site
1081093011908	putative substrate binding pocket (H-site) [chemical binding]; other site
1081093011909	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1081093011910	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1081093011911	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1081093011912	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1081093011913	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1081093011914	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1081093011915	putative dimerization interface [polypeptide binding]; other site
1081093011916	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1081093011917	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1081093011918	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1081093011919	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1081093011920	Na binding site [ion binding]; other site
1081093011921	Predicted membrane protein [Function unknown]; Region: COG3162
1081093011922	acetyl-CoA synthetase; Provisional; Region: PRK00174
1081093011923	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1081093011924	active site
1081093011925	CoA binding site [chemical binding]; other site
1081093011926	acyl-activating enzyme (AAE) consensus motif; other site
1081093011927	AMP binding site [chemical binding]; other site
1081093011928	acetate binding site [chemical binding]; other site
1081093011929	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1081093011930	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1081093011931	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1081093011932	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
1081093011933	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1081093011934	heme lyase subunit NrfE; Provisional; Region: PRK10369
1081093011935	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1081093011936	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1081093011937	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1081093011938	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1081093011939	Sel1-like repeats; Region: SEL1; smart00671
1081093011940	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
1081093011941	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093011942	Coenzyme A binding pocket [chemical binding]; other site
1081093011943	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1081093011944	dimer interface [polypeptide binding]; other site
1081093011945	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1081093011946	hypothetical protein; Provisional; Region: PRK10220
1081093011947	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1081093011948	PhnA protein; Region: PhnA; pfam03831
1081093011949	proline/glycine betaine transporter; Provisional; Region: PRK10642
1081093011950	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093011951	putative substrate translocation pore; other site
1081093011952	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1081093011953	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1081093011954	HAMP domain; Region: HAMP; pfam00672
1081093011955	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093011956	dimer interface [polypeptide binding]; other site
1081093011957	phosphorylation site [posttranslational modification]
1081093011958	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093011959	ATP binding site [chemical binding]; other site
1081093011960	Mg2+ binding site [ion binding]; other site
1081093011961	G-X-G motif; other site
1081093011962	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1081093011963	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093011964	active site
1081093011965	phosphorylation site [posttranslational modification]
1081093011966	intermolecular recognition site; other site
1081093011967	dimerization interface [polypeptide binding]; other site
1081093011968	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093011969	DNA binding site [nucleotide binding]
1081093011970	putative metal dependent hydrolase; Provisional; Region: PRK11598
1081093011971	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1081093011972	Sulfatase; Region: Sulfatase; pfam00884
1081093011973	arginine:agmatin antiporter; Provisional; Region: PRK10644
1081093011974	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
1081093011975	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093011976	arginine decarboxylase; Provisional; Region: PRK15029
1081093011977	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1081093011978	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1081093011979	homodimer interface [polypeptide binding]; other site
1081093011980	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1081093011981	catalytic residue [active]
1081093011982	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1081093011983	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1081093011984	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093011985	alpha-galactosidase; Provisional; Region: PRK15076
1081093011986	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1081093011987	NAD binding site [chemical binding]; other site
1081093011988	sugar binding site [chemical binding]; other site
1081093011989	divalent metal binding site [ion binding]; other site
1081093011990	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1081093011991	dimer interface [polypeptide binding]; other site
1081093011992	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1081093011993	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1081093011994	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1081093011995	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093011996	active site
1081093011997	phosphorylation site [posttranslational modification]
1081093011998	intermolecular recognition site; other site
1081093011999	dimerization interface [polypeptide binding]; other site
1081093012000	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1081093012001	PAS domain; Region: PAS; smart00091
1081093012002	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093012003	ATP binding site [chemical binding]; other site
1081093012004	Mg2+ binding site [ion binding]; other site
1081093012005	G-X-G motif; other site
1081093012006	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1081093012007	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1081093012008	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1081093012009	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
1081093012010	SdiA-regulated; Region: SdiA-regulated; pfam06977
1081093012011	SdiA-regulated; Region: SdiA-regulated; cd09971
1081093012012	putative active site [active]
1081093012013	AraC family transcriptional regulator; Provisional; Region: PRK15186
1081093012014	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093012015	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1081093012016	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093012017	Coenzyme A binding pocket [chemical binding]; other site
1081093012018	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1081093012019	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1081093012020	active site
1081093012021	putative transcriptional regulator; Provisional; Region: PRK11640
1081093012022	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1081093012023	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1081093012024	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1081093012025	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1081093012026	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1081093012027	DsbD alpha interface [polypeptide binding]; other site
1081093012028	catalytic residues [active]
1081093012029	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1081093012030	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1081093012031	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1081093012032	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1081093012033	Aspartase; Region: Aspartase; cd01357
1081093012034	active sites [active]
1081093012035	tetramer interface [polypeptide binding]; other site
1081093012036	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1081093012037	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1081093012038	oligomerisation interface [polypeptide binding]; other site
1081093012039	mobile loop; other site
1081093012040	roof hairpin; other site
1081093012041	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1081093012042	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1081093012043	ring oligomerisation interface [polypeptide binding]; other site
1081093012044	ATP/Mg binding site [chemical binding]; other site
1081093012045	stacking interactions; other site
1081093012046	hinge regions; other site
1081093012047	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1081093012048	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1081093012049	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1081093012050	FeS/SAM binding site; other site
1081093012051	elongation factor P; Validated; Region: PRK00529
1081093012052	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1081093012053	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1081093012054	RNA binding site [nucleotide binding]; other site
1081093012055	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1081093012056	RNA binding site [nucleotide binding]; other site
1081093012057	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1081093012058	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093012059	DNA binding residues [nucleotide binding]
1081093012060	dimerization interface [polypeptide binding]; other site
1081093012061	multidrug efflux system protein; Provisional; Region: PRK11431
1081093012062	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1081093012063	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1081093012064	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1081093012065	Iron-sulfur protein interface; other site
1081093012066	proximal quinone binding site [chemical binding]; other site
1081093012067	C-subunit interface; other site
1081093012068	distal quinone binding site; other site
1081093012069	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1081093012070	D-subunit interface [polypeptide binding]; other site
1081093012071	Iron-sulfur protein interface; other site
1081093012072	proximal quinone binding site [chemical binding]; other site
1081093012073	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1081093012074	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1081093012075	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1081093012076	L-aspartate oxidase; Provisional; Region: PRK06175
1081093012077	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1081093012078	poxB regulator PoxA; Provisional; Region: PRK09350
1081093012079	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1081093012080	motif 1; other site
1081093012081	dimer interface [polypeptide binding]; other site
1081093012082	active site
1081093012083	motif 2; other site
1081093012084	motif 3; other site
1081093012085	inner membrane transporter YjeM; Provisional; Region: PRK15238
1081093012086	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
1081093012087	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1081093012088	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1081093012089	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1081093012090	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1081093012091	GTPase RsgA; Reviewed; Region: PRK12288
1081093012092	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1081093012093	RNA binding site [nucleotide binding]; other site
1081093012094	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1081093012095	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1081093012096	GTP/Mg2+ binding site [chemical binding]; other site
1081093012097	G4 box; other site
1081093012098	G5 box; other site
1081093012099	G1 box; other site
1081093012100	Switch I region; other site
1081093012101	G2 box; other site
1081093012102	G3 box; other site
1081093012103	Switch II region; other site
1081093012104	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1081093012105	catalytic site [active]
1081093012106	putative active site [active]
1081093012107	putative substrate binding site [chemical binding]; other site
1081093012108	dimer interface [polypeptide binding]; other site
1081093012109	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1081093012110	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1081093012111	substrate binding pocket [chemical binding]; other site
1081093012112	membrane-bound complex binding site; other site
1081093012113	hinge residues; other site
1081093012114	ADP-binding protein; Provisional; Region: PRK10646
1081093012115	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1081093012116	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1081093012117	active site
1081093012118	metal binding site [ion binding]; metal-binding site
1081093012119	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1081093012120	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1081093012121	bacterial Hfq-like; Region: Hfq; cd01716
1081093012122	hexamer interface [polypeptide binding]; other site
1081093012123	Sm1 motif; other site
1081093012124	RNA binding site [nucleotide binding]; other site
1081093012125	Sm2 motif; other site
1081093012126	GTPase HflX; Provisional; Region: PRK11058
1081093012127	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1081093012128	HflX GTPase family; Region: HflX; cd01878
1081093012129	G1 box; other site
1081093012130	GTP/Mg2+ binding site [chemical binding]; other site
1081093012131	Switch I region; other site
1081093012132	G2 box; other site
1081093012133	G3 box; other site
1081093012134	Switch II region; other site
1081093012135	G4 box; other site
1081093012136	G5 box; other site
1081093012137	FtsH protease regulator HflK; Provisional; Region: PRK10930
1081093012138	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1081093012139	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1081093012140	FtsH protease regulator HflC; Provisional; Region: PRK11029
1081093012141	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1081093012142	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1081093012143	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1081093012144	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1081093012145	GDP-binding site [chemical binding]; other site
1081093012146	ACT binding site; other site
1081093012147	IMP binding site; other site
1081093012148	Predicted transcriptional regulator [Transcription]; Region: COG1959
1081093012149	transcriptional repressor NsrR; Provisional; Region: PRK11014
1081093012150	exoribonuclease R; Provisional; Region: PRK11642
1081093012151	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1081093012152	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1081093012153	RNB domain; Region: RNB; pfam00773
1081093012154	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1081093012155	RNA binding site [nucleotide binding]; other site
1081093012156	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1081093012157	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1081093012158	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1081093012159	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
1081093012160	Ion channel; Region: Ion_trans_2; pfam07885
1081093012161	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
1081093012162	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
1081093012163	Predicted membrane protein [Function unknown]; Region: COG3766
1081093012164	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1081093012165	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1081093012166	Predicted integral membrane protein [Function unknown]; Region: COG5463
1081093012167	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1081093012168	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1081093012169	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1081093012170	FAD binding site [chemical binding]; other site
1081093012171	substrate binding site [chemical binding]; other site
1081093012172	catalytic residues [active]
1081093012173	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093012174	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1081093012175	esterase; Provisional; Region: PRK10566
1081093012176	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1081093012177	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1081093012178	transcriptional repressor UlaR; Provisional; Region: PRK13509
1081093012179	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1081093012180	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1081093012181	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1081093012182	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1081093012183	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1081093012184	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1081093012185	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1081093012186	active site
1081093012187	P-loop; other site
1081093012188	phosphorylation site [posttranslational modification]
1081093012189	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1081093012190	active site
1081093012191	phosphorylation site [posttranslational modification]
1081093012192	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1081093012193	active site
1081093012194	dimer interface [polypeptide binding]; other site
1081093012195	magnesium binding site [ion binding]; other site
1081093012196	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1081093012197	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1081093012198	AP (apurinic/apyrimidinic) site pocket; other site
1081093012199	DNA interaction; other site
1081093012200	Metal-binding active site; metal-binding site
1081093012201	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1081093012202	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1081093012203	intersubunit interface [polypeptide binding]; other site
1081093012204	active site
1081093012205	Zn2+ binding site [ion binding]; other site
1081093012206	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1081093012207	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1081093012208	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1081093012209	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1081093012210	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1081093012211	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1081093012212	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1081093012213	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1081093012214	EamA-like transporter family; Region: EamA; pfam00892
1081093012215	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1081093012216	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1081093012217	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1081093012218	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1081093012219	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1081093012220	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1081093012221	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1081093012222	DKNYY family; Region: DKNYY; pfam13644
1081093012223	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1081093012224	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1081093012225	Hemerythrin-like domain; Region: Hr-like; cd12108
1081093012226	Fe binding site [ion binding]; other site
1081093012227	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1081093012228	EamA-like transporter family; Region: EamA; pfam00892
1081093012229	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1081093012230	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1081093012231	NADP binding site [chemical binding]; other site
1081093012232	Predicted transcriptional regulators [Transcription]; Region: COG1733
1081093012233	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1081093012234	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1081093012235	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1081093012236	active site
1081093012237	metal binding site [ion binding]; metal-binding site
1081093012238	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1081093012239	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1081093012240	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1081093012241	active site
1081093012242	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1081093012243	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1081093012244	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1081093012245	Domain of unknown function DUF21; Region: DUF21; pfam01595
1081093012246	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1081093012247	Transporter associated domain; Region: CorC_HlyC; smart01091
1081093012248	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1081093012249	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1081093012250	Family of unknown function (DUF490); Region: DUF490; pfam04357
1081093012251	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1081093012252	dimerization interface [polypeptide binding]; other site
1081093012253	putative active site pocket [active]
1081093012254	putative catalytic residue [active]
1081093012255	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093012256	D-galactonate transporter; Region: 2A0114; TIGR00893
1081093012257	putative substrate translocation pore; other site
1081093012258	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
1081093012259	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1081093012260	active site
1081093012261	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1081093012262	dimer interface [polypeptide binding]; other site
1081093012263	substrate binding site [chemical binding]; other site
1081093012264	metal binding sites [ion binding]; metal-binding site
1081093012265	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1081093012266	AMP binding site [chemical binding]; other site
1081093012267	metal binding site [ion binding]; metal-binding site
1081093012268	active site
1081093012269	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1081093012270	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1081093012271	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1081093012272	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1081093012273	hypothetical protein; Provisional; Region: PRK05255
1081093012274	peptidase PmbA; Provisional; Region: PRK11040
1081093012275	cytochrome b562; Provisional; Region: PRK15058
1081093012276	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1081093012277	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
1081093012278	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
1081093012279	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1081093012280	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
1081093012281	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
1081093012282	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1081093012283	active site
1081093012284	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1081093012285	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1081093012286	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1081093012287	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1081093012288	HTH domain; Region: HTH_11; pfam08279
1081093012289	Mga helix-turn-helix domain; Region: Mga; pfam05043
1081093012290	PRD domain; Region: PRD; pfam00874
1081093012291	PRD domain; Region: PRD; pfam00874
1081093012292	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1081093012293	active site
1081093012294	P-loop; other site
1081093012295	phosphorylation site [posttranslational modification]
1081093012296	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1081093012297	active site
1081093012298	phosphorylation site [posttranslational modification]
1081093012299	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
1081093012300	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1081093012301	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1081093012302	ATP cone domain; Region: ATP-cone; pfam03477
1081093012303	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1081093012304	effector binding site; other site
1081093012305	active site
1081093012306	Zn binding site [ion binding]; other site
1081093012307	glycine loop; other site
1081093012308	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1081093012309	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1081093012310	Ca binding site [ion binding]; other site
1081093012311	active site
1081093012312	catalytic site [active]
1081093012313	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1081093012314	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1081093012315	active site turn [active]
1081093012316	phosphorylation site [posttranslational modification]
1081093012317	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1081093012318	trehalose repressor; Provisional; Region: treR; PRK09492
1081093012319	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093012320	DNA binding site [nucleotide binding]
1081093012321	domain linker motif; other site
1081093012322	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1081093012323	dimerization interface [polypeptide binding]; other site
1081093012324	ligand binding site [chemical binding]; other site
1081093012325	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1081093012326	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1081093012327	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1081093012328	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1081093012329	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1081093012330	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1081093012331	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1081093012332	Transposase; Region: HTH_Tnp_1; cl17663
1081093012333	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1081093012334	homotrimer interaction site [polypeptide binding]; other site
1081093012335	putative active site [active]
1081093012336	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1081093012337	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1081093012338	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1081093012339	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1081093012340	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1081093012341	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1081093012342	Arginine repressor [Transcription]; Region: ArgR; COG1438
1081093012343	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1081093012344	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1081093012345	Predicted membrane protein [Function unknown]; Region: COG1288
1081093012346	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1081093012347	ornithine carbamoyltransferase; Validated; Region: PRK02102
1081093012348	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1081093012349	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1081093012350	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1081093012351	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1081093012352	putative substrate binding site [chemical binding]; other site
1081093012353	nucleotide binding site [chemical binding]; other site
1081093012354	nucleotide binding site [chemical binding]; other site
1081093012355	homodimer interface [polypeptide binding]; other site
1081093012356	arginine deiminase; Provisional; Region: PRK01388
1081093012357	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1081093012358	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1081093012359	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1081093012360	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1081093012361	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
1081093012362	RNase E inhibitor protein; Provisional; Region: PRK11191
1081093012363	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1081093012364	active site
1081093012365	dinuclear metal binding site [ion binding]; other site
1081093012366	dimerization interface [polypeptide binding]; other site
1081093012367	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
1081093012368	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1081093012369	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093012370	Coenzyme A binding pocket [chemical binding]; other site
1081093012371	Predicted membrane protein [Function unknown]; Region: COG4269
1081093012372	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1081093012373	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1081093012374	HIGH motif; other site
1081093012375	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1081093012376	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1081093012377	active site
1081093012378	KMSKS motif; other site
1081093012379	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1081093012380	tRNA binding surface [nucleotide binding]; other site
1081093012381	anticodon binding site; other site
1081093012382	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1081093012383	DNA polymerase III subunit chi; Validated; Region: PRK05728
1081093012384	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1081093012385	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1081093012386	interface (dimer of trimers) [polypeptide binding]; other site
1081093012387	Substrate-binding/catalytic site; other site
1081093012388	Zn-binding sites [ion binding]; other site
1081093012389	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1081093012390	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1081093012391	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1081093012392	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1081093012393	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1081093012394	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1081093012395	DNA binding site [nucleotide binding]
1081093012396	domain linker motif; other site
1081093012397	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1081093012398	putative dimerization interface [polypeptide binding]; other site
1081093012399	putative ligand binding site [chemical binding]; other site
1081093012400	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1081093012401	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1081093012402	putative NAD(P) binding site [chemical binding]; other site
1081093012403	catalytic Zn binding site [ion binding]; other site
1081093012404	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1081093012405	ATP-binding site [chemical binding]; other site
1081093012406	Gluconate-6-phosphate binding site [chemical binding]; other site
1081093012407	Shikimate kinase; Region: SKI; pfam01202
1081093012408	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1081093012409	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1081093012410	putative NAD(P) binding site [chemical binding]; other site
1081093012411	putative substrate binding site [chemical binding]; other site
1081093012412	catalytic Zn binding site [ion binding]; other site
1081093012413	structural Zn binding site [ion binding]; other site
1081093012414	dimer interface [polypeptide binding]; other site
1081093012415	Winged helix-turn helix; Region: HTH_29; pfam13551
1081093012416	Homeodomain-like domain; Region: HTH_23; pfam13384
1081093012417	Homeodomain-like domain; Region: HTH_32; pfam13565
1081093012418	Methyltransferase domain; Region: Methyltransf_27; pfam13708
1081093012419	Predicted transcriptional regulator [Transcription]; Region: COG3905
1081093012420	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
1081093012421	CcdB protein; Region: CcdB; pfam01845
1081093012422	Integrase core domain; Region: rve; pfam00665
1081093012423	Integrase core domain; Region: rve_2; pfam13333
1081093012424	HTH-like domain; Region: HTH_21; pfam13276
1081093012425	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1081093012426	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093012427	FaeA-like protein; Region: FaeA; pfam04703
1081093012428	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093012429	DNA binding residues [nucleotide binding]
1081093012430	dimerization interface [polypeptide binding]; other site
1081093012431	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1081093012432	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1081093012433	catalytic residues [active]
1081093012434	hinge region; other site
1081093012435	alpha helical domain; other site
1081093012436	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1081093012437	SdiA-regulated; Region: SdiA-regulated; cd09971
1081093012438	putative active site [active]
1081093012439	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1081093012440	DNA-binding interface [nucleotide binding]; DNA binding site
1081093012441	hypothetical protein; Provisional; Region: PRK12378
1081093012442	hypothetical protein; Provisional; Region: PRK13687
1081093012443	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1081093012444	Uncharacterized conserved protein [Function unknown]; Region: COG3439
1081093012445	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1081093012446	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1081093012447	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1081093012448	DNA-binding site [nucleotide binding]; DNA binding site
1081093012449	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1081093012450	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1081093012451	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1081093012452	active site
1081093012453	HIGH motif; other site
1081093012454	dimer interface [polypeptide binding]; other site
1081093012455	KMSKS motif; other site
1081093012456	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1081093012457	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1081093012458	aspartate racemase; Region: asp_race; TIGR00035
1081093012459	isoaspartyl dipeptidase; Provisional; Region: PRK10657
1081093012460	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1081093012461	active site
1081093012462	hypothetical protein; Provisional; Region: PRK10519
1081093012463	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1081093012464	Nucleoside recognition; Region: Gate; pfam07670
1081093012465	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
1081093012466	Predicted membrane protein [Function unknown]; Region: COG2733
1081093012467	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1081093012468	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1081093012469	putative substrate translocation pore; other site
1081093012470	putative transposase; Provisional; Region: PRK09857
1081093012471	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1081093012472	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1081093012473	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1081093012474	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1081093012475	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1081093012476	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1081093012477	Nuclease-related domain; Region: NERD; pfam08378
1081093012478	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
1081093012479	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1081093012480	ATP binding site [chemical binding]; other site
1081093012481	putative Mg++ binding site [ion binding]; other site
1081093012482	Family description; Region: UvrD_C_2; pfam13538
1081093012483	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
1081093012484	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
1081093012485	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1081093012486	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1081093012487	P-loop, Walker A motif; other site
1081093012488	Base recognition motif; other site
1081093012489	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1081093012490	Uncharacterized small protein [Function unknown]; Region: COG2879
1081093012491	carbon starvation protein A; Provisional; Region: PRK15015
1081093012492	Carbon starvation protein CstA; Region: CstA; pfam02554
1081093012493	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1081093012494	methyl-accepting protein IV; Provisional; Region: PRK09793
1081093012495	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1081093012496	dimer interface [polypeptide binding]; other site
1081093012497	ligand binding site [chemical binding]; other site
1081093012498	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1081093012499	dimerization interface [polypeptide binding]; other site
1081093012500	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1081093012501	dimer interface [polypeptide binding]; other site
1081093012502	putative CheW interface [polypeptide binding]; other site
1081093012503	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1081093012504	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093012505	Walker A motif; other site
1081093012506	ATP binding site [chemical binding]; other site
1081093012507	Walker B motif; other site
1081093012508	arginine finger; other site
1081093012509	Transcriptional antiterminator [Transcription]; Region: COG3933
1081093012510	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1081093012511	active pocket/dimerization site; other site
1081093012512	active site
1081093012513	phosphorylation site [posttranslational modification]
1081093012514	PRD domain; Region: PRD; pfam00874
1081093012515	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1081093012516	active pocket/dimerization site; other site
1081093012517	active site
1081093012518	phosphorylation site [posttranslational modification]
1081093012519	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1081093012520	active site
1081093012521	phosphorylation site [posttranslational modification]
1081093012522	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1081093012523	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1081093012524	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1081093012525	dimer interface [polypeptide binding]; other site
1081093012526	active site
1081093012527	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1081093012528	dimer interface [polypeptide binding]; other site
1081093012529	active site
1081093012530	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1081093012531	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1081093012532	putative active site [active]
1081093012533	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
1081093012534	phosphoglycerol transferase I; Provisional; Region: PRK03776
1081093012535	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1081093012536	hypothetical protein; Provisional; Region: PRK11667
1081093012537	DNA replication protein DnaC; Validated; Region: PRK07952
1081093012538	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1081093012539	Walker A motif; other site
1081093012540	ATP binding site [chemical binding]; other site
1081093012541	Walker B motif; other site
1081093012542	primosomal protein DnaI; Provisional; Region: PRK02854
1081093012543	hypothetical protein; Provisional; Region: PRK09917
1081093012544	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1081093012545	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1081093012546	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1081093012547	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093012548	DNA binding residues [nucleotide binding]
1081093012549	dimerization interface [polypeptide binding]; other site
1081093012550	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1081093012551	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1081093012552	DNA binding residues [nucleotide binding]
1081093012553	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1081093012554	putative deacylase active site [active]
1081093012555	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1081093012556	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1081093012557	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1081093012558	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1081093012559	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1081093012560	metal binding site [ion binding]; metal-binding site
1081093012561	active site
1081093012562	I-site; other site
1081093012563	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1081093012564	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1081093012565	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1081093012566	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1081093012567	S-adenosylmethionine binding site [chemical binding]; other site
1081093012568	DNA polymerase III subunit psi; Validated; Region: PRK06856
1081093012569	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1081093012570	Coenzyme A binding pocket [chemical binding]; other site
1081093012571	dUMP phosphatase; Provisional; Region: PRK09449
1081093012572	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093012573	motif II; other site
1081093012574	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1081093012575	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1081093012576	G1 box; other site
1081093012577	putative GEF interaction site [polypeptide binding]; other site
1081093012578	GTP/Mg2+ binding site [chemical binding]; other site
1081093012579	Switch I region; other site
1081093012580	G2 box; other site
1081093012581	G3 box; other site
1081093012582	Switch II region; other site
1081093012583	G4 box; other site
1081093012584	G5 box; other site
1081093012585	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1081093012586	periplasmic protein; Provisional; Region: PRK10568
1081093012587	BON domain; Region: BON; pfam04972
1081093012588	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1081093012589	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1081093012590	active site
1081093012591	nucleophile elbow; other site
1081093012592	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1081093012593	active site
1081093012594	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1081093012595	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1081093012596	Pyruvate-formate lyase-activating enzyme [Posttranslational modification, protein turnover, chaperones]; Region: PflA; COG1180
1081093012597	hypothetical protein; Provisional; Region: PRK10977
1081093012598	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1081093012599	intersubunit interface [polypeptide binding]; other site
1081093012600	active site
1081093012601	catalytic residue [active]
1081093012602	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1081093012603	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1081093012604	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1081093012605	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1081093012606	phosphopentomutase; Provisional; Region: PRK05362
1081093012607	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1081093012608	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1081093012609	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1081093012610	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09775
1081093012611	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1081093012612	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1081093012613	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1081093012614	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1081093012615	hypothetical protein; Provisional; Region: PRK11246
1081093012616	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1081093012617	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1081093012618	motif II; other site
1081093012619	DNA repair protein RadA; Region: sms; TIGR00416
1081093012620	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1081093012621	Walker A motif/ATP binding site; other site
1081093012622	ATP binding site [chemical binding]; other site
1081093012623	Walker B motif; other site
1081093012624	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1081093012625	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1081093012626	non-specific DNA binding site [nucleotide binding]; other site
1081093012627	salt bridge; other site
1081093012628	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1081093012629	sequence-specific DNA binding site [nucleotide binding]; other site
1081093012630	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1081093012631	active site
1081093012632	(T/H)XGH motif; other site
1081093012633	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1081093012634	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1081093012635	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093012636	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093012637	ABC transporter; Region: ABC_tran_2; pfam12848
1081093012638	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1081093012639	lytic murein transglycosylase; Provisional; Region: PRK11619
1081093012640	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1081093012641	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1081093012642	catalytic residue [active]
1081093012643	Trp operon repressor; Provisional; Region: PRK01381
1081093012644	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1081093012645	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1081093012646	catalytic core [active]
1081093012647	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1081093012648	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1081093012649	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1081093012650	hypothetical protein; Provisional; Region: PRK10756
1081093012651	CreA protein; Region: CreA; pfam05981
1081093012652	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1081093012653	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093012654	active site
1081093012655	phosphorylation site [posttranslational modification]
1081093012656	intermolecular recognition site; other site
1081093012657	dimerization interface [polypeptide binding]; other site
1081093012658	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093012659	DNA binding site [nucleotide binding]
1081093012660	sensory histidine kinase CreC; Provisional; Region: PRK11100
1081093012661	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1081093012662	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1081093012663	dimer interface [polypeptide binding]; other site
1081093012664	phosphorylation site [posttranslational modification]
1081093012665	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1081093012666	ATP binding site [chemical binding]; other site
1081093012667	Mg2+ binding site [ion binding]; other site
1081093012668	G-X-G motif; other site
1081093012669	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
1081093012670	putative fimbrial protein SthD; Provisional; Region: PRK15293
1081093012671	putative fimbrial outer membrane usher protein SthC; Provisional; Region: PRK15294
1081093012672	PapC N-terminal domain; Region: PapC_N; pfam13954
1081093012673	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1081093012674	PapC C-terminal domain; Region: PapC_C; pfam13953
1081093012675	putative fimbrial protein SthA; Provisional; Region: PRK15296
1081093012676	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1081093012677	Helix-turn-helix domain; Region: HTH_36; pfam13730
1081093012678	two-component response regulator; Provisional; Region: PRK11173
1081093012679	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1081093012680	active site
1081093012681	phosphorylation site [posttranslational modification]
1081093012682	intermolecular recognition site; other site
1081093012683	dimerization interface [polypeptide binding]; other site
1081093012684	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1081093012685	DNA binding site [nucleotide binding]
1081093012686	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1081093012687	putative RNA methyltransferase; Provisional; Region: PRK10433