-- dump date   	20140620_053905
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1267753000001	potential frameshift: common BLAST hit: gi|410609884|ref|YP_006954092.1| Error-prone repair protein UmuC
1267753000002	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1267753000003	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1267753000004	Catalytic site [active]
1267753000005	Uncharacterized ACR, COG2135; Region: DUF159; cl03646
1267753000006	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
1267753000007	potential frameshift: common BLAST hit: gi|409248454|ref|YP_004193481.1| conjugal transfer nickase/helicase TraI
1267753000008	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
1267753000009	TraX protein; Region: TraX; cl05434
1267753000010	Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170
1267753000011	PLD-like domain; Region: PLDc_2; pfam13091
1267753000012	putative active site [active]
1267753000013	catalytic site [active]
1267753000014	Replication regulatory protein RepB; Region: RepB-RCR_reg; cl11673
1267753000015	Tap RepA1 leader peptide; Region: RepA1_leader; pfam08048
1267753000016	Domain of unknown function (DUF305); Region: DUF305; cl17794
1267753000017	Protein of unknown function (DUF2913); Region: DUF2913; pfam11140
1267753000018	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1267753000019	Transposase; Region: HTH_Tnp_1; cl17663
1267753000020	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1267753000021	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753000022	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753000023	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1267753000024	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753000025	active site
1267753000026	dimerization interface [polypeptide binding]; other site
1267753000027	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753000028	DNA binding site [nucleotide binding]
1267753000029	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1267753000030	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
1267753000031	DNA binding residues [nucleotide binding]
1267753000032	dimerization interface [polypeptide binding]; other site
1267753000033	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1267753000034	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753000035	Q-loop/lid; other site
1267753000036	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753000037	Walker B; other site
1267753000038	D-loop; other site
1267753000039	H-loop/switch region; other site
1267753000040	heme exporter protein CcmC; Region: ccmC; TIGR01191
1267753000041	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1267753000042	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1267753000043	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1267753000044	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1267753000045	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1267753000046	catalytic residues [active]
1267753000047	central insert; other site
1267753000048	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1267753000049	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1267753000050	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1267753000051	binding surface
1267753000052	TPR motif; other site
1267753000053	transcriptional regulator NarP; Provisional; Region: PRK10403
1267753000054	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753000055	active site
1267753000056	phosphorylation site [posttranslational modification]
1267753000057	intermolecular recognition site; other site
1267753000058	dimerization interface [polypeptide binding]; other site
1267753000059	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753000060	DNA binding residues [nucleotide binding]
1267753000061	dimerization interface [polypeptide binding]; other site
1267753000062	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
1267753000063	DinI-like family; Region: DinI; cl11630
1267753000064	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
1267753000065	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
1267753000066	Sulfatase; Region: Sulfatase; cl17466
1267753000067	hypothetical protein; Provisional; Region: PRK13689
1267753000068	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1267753000069	nucleoid-associated protein NdpA; Validated; Region: PRK00378
1267753000070	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1267753000071	5S rRNA interface [nucleotide binding]; other site
1267753000072	CTC domain interface [polypeptide binding]; other site
1267753000073	L16 interface [polypeptide binding]; other site
1267753000074	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1267753000075	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753000076	ATP binding site [chemical binding]; other site
1267753000077	putative Mg++ binding site [ion binding]; other site
1267753000078	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753000079	nucleotide binding region [chemical binding]; other site
1267753000080	ATP-binding site [chemical binding]; other site
1267753000081	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
1267753000082	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
1267753000083	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1267753000084	RNA binding surface [nucleotide binding]; other site
1267753000085	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1267753000086	active site
1267753000087	uracil binding [chemical binding]; other site
1267753000088	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753000089	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
1267753000090	putative substrate translocation pore; other site
1267753000091	hypothetical protein; Provisional; Region: PRK11835
1267753000092	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
1267753000093	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753000094	Walker A/P-loop; other site
1267753000095	ATP binding site [chemical binding]; other site
1267753000096	Q-loop/lid; other site
1267753000097	ABC transporter signature motif; other site
1267753000098	Walker B; other site
1267753000099	D-loop; other site
1267753000100	H-loop/switch region; other site
1267753000101	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1267753000102	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753000103	Walker A/P-loop; other site
1267753000104	ATP binding site [chemical binding]; other site
1267753000105	Q-loop/lid; other site
1267753000106	ABC transporter signature motif; other site
1267753000107	Walker B; other site
1267753000108	D-loop; other site
1267753000109	H-loop/switch region; other site
1267753000110	microcin C ABC transporter permease; Provisional; Region: PRK15021
1267753000111	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753000112	dimer interface [polypeptide binding]; other site
1267753000113	conserved gate region; other site
1267753000114	ABC-ATPase subunit interface; other site
1267753000115	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
1267753000116	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753000117	dimer interface [polypeptide binding]; other site
1267753000118	conserved gate region; other site
1267753000119	putative PBP binding loops; other site
1267753000120	ABC-ATPase subunit interface; other site
1267753000121	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1267753000122	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
1267753000123	phage resistance protein; Provisional; Region: PRK10551
1267753000124	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1267753000125	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753000126	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
1267753000127	NlpC/P60 family; Region: NLPC_P60; pfam00877
1267753000128	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1267753000129	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1267753000130	active site
1267753000131	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1267753000132	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1267753000133	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1267753000134	elongation factor P; Provisional; Region: PRK04542
1267753000135	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1267753000136	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1267753000137	RNA binding site [nucleotide binding]; other site
1267753000138	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1267753000139	RNA binding site [nucleotide binding]; other site
1267753000140	Flagellin N-methylase; Region: FliB; cl00497
1267753000141	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1267753000142	sugar efflux transporter B; Provisional; Region: PRK15011
1267753000143	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753000144	putative substrate translocation pore; other site
1267753000145	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
1267753000146	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753000147	active site
1267753000148	phosphorylation site [posttranslational modification]
1267753000149	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1267753000150	dimerization domain swap beta strand [polypeptide binding]; other site
1267753000151	regulatory protein interface [polypeptide binding]; other site
1267753000152	active site
1267753000153	regulatory phosphorylation site [posttranslational modification]; other site
1267753000154	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1267753000155	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1267753000156	putative substrate binding site [chemical binding]; other site
1267753000157	putative ATP binding site [chemical binding]; other site
1267753000158	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
1267753000159	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
1267753000160	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1267753000161	active site
1267753000162	P-loop; other site
1267753000163	phosphorylation site [posttranslational modification]
1267753000164	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1267753000165	endonuclease IV; Provisional; Region: PRK01060
1267753000166	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1267753000167	AP (apurinic/apyrimidinic) site pocket; other site
1267753000168	DNA interaction; other site
1267753000169	Metal-binding active site; metal-binding site
1267753000170	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
1267753000171	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1267753000172	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753000173	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1267753000174	putative dimerization interface [polypeptide binding]; other site
1267753000175	lysine transporter; Provisional; Region: PRK10836
1267753000176	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
1267753000177	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1267753000178	N-terminal plug; other site
1267753000179	ligand-binding site [chemical binding]; other site
1267753000180	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1267753000181	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753000182	putative substrate translocation pore; other site
1267753000183	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1267753000184	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1267753000185	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753000186	motif II; other site
1267753000187	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1267753000188	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1267753000189	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1267753000190	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753000191	non-specific DNA binding site [nucleotide binding]; other site
1267753000192	salt bridge; other site
1267753000193	sequence-specific DNA binding site [nucleotide binding]; other site
1267753000194	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
1267753000195	S-formylglutathione hydrolase; Region: PLN02442
1267753000196	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1267753000197	GTP cyclohydrolase I; Provisional; Region: PLN03044
1267753000198	active site
1267753000199	Predicted membrane protein [Function unknown]; Region: COG2311
1267753000200	hypothetical protein; Provisional; Region: PRK10835
1267753000201	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
1267753000202	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753000203	DNA binding site [nucleotide binding]
1267753000204	domain linker motif; other site
1267753000205	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1267753000206	dimerization interface (closed form) [polypeptide binding]; other site
1267753000207	ligand binding site [chemical binding]; other site
1267753000208	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
1267753000209	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
1267753000210	ligand binding site [chemical binding]; other site
1267753000211	calcium binding site [ion binding]; other site
1267753000212	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1267753000213	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
1267753000214	Walker A/P-loop; other site
1267753000215	ATP binding site [chemical binding]; other site
1267753000216	Q-loop/lid; other site
1267753000217	ABC transporter signature motif; other site
1267753000218	Walker B; other site
1267753000219	D-loop; other site
1267753000220	H-loop/switch region; other site
1267753000221	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1267753000222	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1267753000223	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1267753000224	TM-ABC transporter signature motif; other site
1267753000225	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
1267753000226	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
1267753000227	homodimer interface [polypeptide binding]; other site
1267753000228	active site
1267753000229	FMN binding site [chemical binding]; other site
1267753000230	substrate binding site [chemical binding]; other site
1267753000231	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1267753000232	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1267753000233	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753000234	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
1267753000235	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1267753000236	putative active site [active]
1267753000237	cytidine deaminase; Provisional; Region: PRK09027
1267753000238	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1267753000239	active site
1267753000240	catalytic motif [active]
1267753000241	Zn binding site [ion binding]; other site
1267753000242	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1267753000243	active site
1267753000244	catalytic motif [active]
1267753000245	Zn binding site [ion binding]; other site
1267753000246	hypothetical protein; Provisional; Region: PRK10711
1267753000247	hypothetical protein; Provisional; Region: PRK01821
1267753000248	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1267753000249	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753000250	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1267753000251	dimerization interface [polypeptide binding]; other site
1267753000252	benzoate transport; Region: 2A0115; TIGR00895
1267753000253	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753000254	putative substrate translocation pore; other site
1267753000255	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
1267753000256	Cupin domain; Region: Cupin_2; pfam07883
1267753000257	Cupin domain; Region: Cupin_2; pfam07883
1267753000258	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1267753000259	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1267753000260	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
1267753000261	maleylacetoacetate isomerase; Region: maiA; TIGR01262
1267753000262	C-terminal domain interface [polypeptide binding]; other site
1267753000263	GSH binding site (G-site) [chemical binding]; other site
1267753000264	putative dimer interface [polypeptide binding]; other site
1267753000265	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
1267753000266	dimer interface [polypeptide binding]; other site
1267753000267	N-terminal domain interface [polypeptide binding]; other site
1267753000268	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
1267753000269	salicylate hydroxylase; Provisional; Region: PRK08163
1267753000270	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1267753000271	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
1267753000272	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1267753000273	FMN binding site [chemical binding]; other site
1267753000274	active site
1267753000275	catalytic residues [active]
1267753000276	substrate binding site [chemical binding]; other site
1267753000277	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
1267753000278	oxidoreductase; Provisional; Region: PRK12743
1267753000279	classical (c) SDRs; Region: SDR_c; cd05233
1267753000280	NAD(P) binding site [chemical binding]; other site
1267753000281	active site
1267753000282	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1267753000283	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1267753000284	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
1267753000285	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
1267753000286	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1267753000287	D-lactate dehydrogenase; Provisional; Region: PRK11183
1267753000288	FAD binding domain; Region: FAD_binding_4; pfam01565
1267753000289	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
1267753000290	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1267753000291	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1267753000292	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1267753000293	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1267753000294	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753000295	dimer interface [polypeptide binding]; other site
1267753000296	conserved gate region; other site
1267753000297	ABC-ATPase subunit interface; other site
1267753000298	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1267753000299	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1267753000300	Walker A/P-loop; other site
1267753000301	ATP binding site [chemical binding]; other site
1267753000302	Q-loop/lid; other site
1267753000303	ABC transporter signature motif; other site
1267753000304	Walker B; other site
1267753000305	D-loop; other site
1267753000306	H-loop/switch region; other site
1267753000307	CBS domain; Region: CBS; pfam00571
1267753000308	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
1267753000309	hypothetical protein; Provisional; Region: PRK13681
1267753000310	transcriptional regulator MirA; Provisional; Region: PRK15043
1267753000311	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
1267753000312	DNA binding residues [nucleotide binding]
1267753000313	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1267753000314	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1267753000315	GAF domain; Region: GAF; pfam01590
1267753000316	Histidine kinase; Region: His_kinase; pfam06580
1267753000317	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753000318	ATP binding site [chemical binding]; other site
1267753000319	Mg2+ binding site [ion binding]; other site
1267753000320	G-X-G motif; other site
1267753000321	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
1267753000322	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753000323	active site
1267753000324	phosphorylation site [posttranslational modification]
1267753000325	intermolecular recognition site; other site
1267753000326	dimerization interface [polypeptide binding]; other site
1267753000327	LytTr DNA-binding domain; Region: LytTR; pfam04397
1267753000328	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
1267753000329	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1267753000330	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1267753000331	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1267753000332	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
1267753000333	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1267753000334	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1267753000335	active site
1267753000336	HIGH motif; other site
1267753000337	KMSKS motif; other site
1267753000338	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1267753000339	tRNA binding surface [nucleotide binding]; other site
1267753000340	anticodon binding site; other site
1267753000341	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1267753000342	dimer interface [polypeptide binding]; other site
1267753000343	putative tRNA-binding site [nucleotide binding]; other site
1267753000344	antiporter inner membrane protein; Provisional; Region: PRK11670
1267753000345	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1267753000346	Walker A motif; other site
1267753000347	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
1267753000348	fimbrial chaperone protein; Provisional; Region: PRK15220
1267753000349	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
1267753000350	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753000351	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753000352	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
1267753000353	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753000354	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753000355	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753000356	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
1267753000357	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
1267753000358	Predicted integral membrane protein [Function unknown]; Region: COG5455
1267753000359	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1267753000360	substrate binding site [chemical binding]; other site
1267753000361	multimerization interface [polypeptide binding]; other site
1267753000362	ATP binding site [chemical binding]; other site
1267753000363	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1267753000364	dimer interface [polypeptide binding]; other site
1267753000365	substrate binding site [chemical binding]; other site
1267753000366	ATP binding site [chemical binding]; other site
1267753000367	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1267753000368	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753000369	DNA-binding site [nucleotide binding]; DNA binding site
1267753000370	UTRA domain; Region: UTRA; pfam07702
1267753000371	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753000372	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1267753000373	substrate binding site [chemical binding]; other site
1267753000374	ATP binding site [chemical binding]; other site
1267753000375	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1267753000376	nucleoside transporter; Region: 2A0110; TIGR00889
1267753000377	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753000378	putative substrate translocation pore; other site
1267753000379	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
1267753000380	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1267753000381	putative active site; other site
1267753000382	catalytic residue [active]
1267753000383	lipid kinase; Reviewed; Region: PRK13054
1267753000384	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1267753000385	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
1267753000386	type III secretion system protein; Provisional; Region: PRK15384; cl14665
1267753000387	putative protease; Provisional; Region: PRK15452
1267753000388	Peptidase family U32; Region: Peptidase_U32; pfam01136
1267753000389	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
1267753000390	potential frameshift: common BLAST hit: gi|379701359|ref|YP_005243087.1| putative inner membrane protein
1267753000391	PcfJ-like protein; Region: PcfJ; pfam14284
1267753000392	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
1267753000393	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753000394	active site
1267753000395	phosphorylation site [posttranslational modification]
1267753000396	intermolecular recognition site; other site
1267753000397	dimerization interface [polypeptide binding]; other site
1267753000398	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753000399	DNA binding site [nucleotide binding]
1267753000400	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
1267753000401	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753000402	dimerization interface [polypeptide binding]; other site
1267753000403	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753000404	dimer interface [polypeptide binding]; other site
1267753000405	phosphorylation site [posttranslational modification]
1267753000406	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753000407	ATP binding site [chemical binding]; other site
1267753000408	Mg2+ binding site [ion binding]; other site
1267753000409	G-X-G motif; other site
1267753000410	putative transporter; Provisional; Region: PRK10504
1267753000411	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753000412	putative substrate translocation pore; other site
1267753000413	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1267753000414	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
1267753000415	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
1267753000416	Protein export membrane protein; Region: SecD_SecF; cl14618
1267753000417	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
1267753000418	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753000419	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753000420	putative chaperone; Provisional; Region: PRK11678
1267753000421	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
1267753000422	nucleotide binding site [chemical binding]; other site
1267753000423	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1267753000424	SBD interface [polypeptide binding]; other site
1267753000425	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
1267753000426	AlkA N-terminal domain; Region: AlkA_N; pfam06029
1267753000427	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1267753000428	minor groove reading motif; other site
1267753000429	helix-hairpin-helix signature motif; other site
1267753000430	substrate binding pocket [chemical binding]; other site
1267753000431	active site
1267753000432	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
1267753000433	PAS domain S-box; Region: sensory_box; TIGR00229
1267753000434	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1267753000435	putative active site [active]
1267753000436	heme pocket [chemical binding]; other site
1267753000437	PAS domain S-box; Region: sensory_box; TIGR00229
1267753000438	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1267753000439	putative active site [active]
1267753000440	heme pocket [chemical binding]; other site
1267753000441	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1267753000442	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753000443	metal binding site [ion binding]; metal-binding site
1267753000444	active site
1267753000445	I-site; other site
1267753000446	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753000447	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1267753000448	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1267753000449	ATP-binding site [chemical binding]; other site
1267753000450	Sugar specificity; other site
1267753000451	Pyrimidine base specificity; other site
1267753000452	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1267753000453	trimer interface [polypeptide binding]; other site
1267753000454	active site
1267753000455	putative assembly protein; Provisional; Region: PRK10833
1267753000456	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1267753000457	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1267753000458	FOG: CBS domain [General function prediction only]; Region: COG0517
1267753000459	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1267753000460	Transporter associated domain; Region: CorC_HlyC; smart01091
1267753000461	polysaccharide export protein Wza; Provisional; Region: PRK15078
1267753000462	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1267753000463	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1267753000464	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1267753000465	active site
1267753000466	tyrosine kinase; Provisional; Region: PRK11519
1267753000467	Chain length determinant protein; Region: Wzz; pfam02706
1267753000468	Chain length determinant protein; Region: Wzz; cl15801
1267753000469	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1267753000470	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1267753000471	putative glycosyl transferase; Provisional; Region: PRK10018
1267753000472	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1267753000473	active site
1267753000474	putative acyl transferase; Provisional; Region: PRK10191
1267753000475	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1267753000476	trimer interface [polypeptide binding]; other site
1267753000477	active site
1267753000478	substrate binding site [chemical binding]; other site
1267753000479	CoA binding site [chemical binding]; other site
1267753000480	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
1267753000481	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1267753000482	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1267753000483	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
1267753000484	putative glycosyl transferase; Provisional; Region: PRK10063
1267753000485	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
1267753000486	metal-binding site
1267753000487	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
1267753000488	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
1267753000489	putative trimer interface [polypeptide binding]; other site
1267753000490	putative active site [active]
1267753000491	putative substrate binding site [chemical binding]; other site
1267753000492	putative CoA binding site [chemical binding]; other site
1267753000493	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1267753000494	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1267753000495	NADP-binding site; other site
1267753000496	homotetramer interface [polypeptide binding]; other site
1267753000497	substrate binding site [chemical binding]; other site
1267753000498	homodimer interface [polypeptide binding]; other site
1267753000499	active site
1267753000500	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1267753000501	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1267753000502	NADP binding site [chemical binding]; other site
1267753000503	active site
1267753000504	putative substrate binding site [chemical binding]; other site
1267753000505	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
1267753000506	active site
1267753000507	GDP-Mannose binding site [chemical binding]; other site
1267753000508	dimer interface [polypeptide binding]; other site
1267753000509	modified nudix motif
1267753000510	metal binding site [ion binding]; metal-binding site
1267753000511	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
1267753000512	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1267753000513	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
1267753000514	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1267753000515	Substrate binding site; other site
1267753000516	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1267753000517	phosphomannomutase CpsG; Provisional; Region: PRK15414
1267753000518	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1267753000519	active site
1267753000520	substrate binding site [chemical binding]; other site
1267753000521	metal binding site [ion binding]; metal-binding site
1267753000522	colanic acid exporter; Provisional; Region: PRK10459
1267753000523	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
1267753000524	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; cl09156
1267753000525	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
1267753000526	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
1267753000527	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
1267753000528	putative ADP-binding pocket [chemical binding]; other site
1267753000529	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
1267753000530	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1267753000531	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1267753000532	active site
1267753000533	tetramer interface; other site
1267753000534	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
1267753000535	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1267753000536	NAD binding site [chemical binding]; other site
1267753000537	substrate binding site [chemical binding]; other site
1267753000538	homodimer interface [polypeptide binding]; other site
1267753000539	active site
1267753000540	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
1267753000541	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1267753000542	NADP binding site [chemical binding]; other site
1267753000543	active site
1267753000544	putative substrate binding site [chemical binding]; other site
1267753000545	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
1267753000546	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1267753000547	substrate binding site; other site
1267753000548	tetramer interface; other site
1267753000549	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1267753000550	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
1267753000551	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1267753000552	catalytic loop [active]
1267753000553	iron binding site [ion binding]; other site
1267753000554	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1267753000555	FAD binding pocket [chemical binding]; other site
1267753000556	FAD binding motif [chemical binding]; other site
1267753000557	phosphate binding motif [ion binding]; other site
1267753000558	beta-alpha-beta structure motif; other site
1267753000559	NAD binding pocket [chemical binding]; other site
1267753000560	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1267753000561	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1267753000562	substrate binding site; other site
1267753000563	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1267753000564	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
1267753000565	NAD binding site [chemical binding]; other site
1267753000566	homotetramer interface [polypeptide binding]; other site
1267753000567	homodimer interface [polypeptide binding]; other site
1267753000568	substrate binding site [chemical binding]; other site
1267753000569	active site
1267753000570	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1267753000571	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1267753000572	inhibitor-cofactor binding pocket; inhibition site
1267753000573	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753000574	catalytic residue [active]
1267753000575	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1267753000576	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1267753000577	NAD(P) binding site [chemical binding]; other site
1267753000578	active site
1267753000579	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
1267753000580	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1267753000581	NAD binding site [chemical binding]; other site
1267753000582	homotetramer interface [polypeptide binding]; other site
1267753000583	homodimer interface [polypeptide binding]; other site
1267753000584	active site
1267753000585	substrate binding site [chemical binding]; other site
1267753000586	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1267753000587	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
1267753000588	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1267753000589	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1267753000590	active site
1267753000591	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1267753000592	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1267753000593	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1267753000594	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1267753000595	active site
1267753000596	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1267753000597	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
1267753000598	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1267753000599	Substrate binding site; other site
1267753000600	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
1267753000601	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1267753000602	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
1267753000603	active site
1267753000604	substrate binding site [chemical binding]; other site
1267753000605	metal binding site [ion binding]; metal-binding site
1267753000606	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
1267753000607	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1267753000608	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1267753000609	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1267753000610	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1267753000611	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1267753000612	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
1267753000613	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1267753000614	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1267753000615	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1267753000616	chain length determinant protein WzzB; Provisional; Region: PRK15471
1267753000617	Chain length determinant protein; Region: Wzz; pfam02706
1267753000618	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
1267753000619	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1267753000620	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1267753000621	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1267753000622	metal binding site [ion binding]; metal-binding site
1267753000623	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1267753000624	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1267753000625	substrate binding site [chemical binding]; other site
1267753000626	glutamase interaction surface [polypeptide binding]; other site
1267753000627	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1267753000628	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1267753000629	catalytic residues [active]
1267753000630	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1267753000631	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1267753000632	putative active site [active]
1267753000633	oxyanion strand; other site
1267753000634	catalytic triad [active]
1267753000635	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1267753000636	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753000637	active site
1267753000638	motif I; other site
1267753000639	motif II; other site
1267753000640	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1267753000641	putative active site pocket [active]
1267753000642	4-fold oligomerization interface [polypeptide binding]; other site
1267753000643	metal binding residues [ion binding]; metal-binding site
1267753000644	3-fold/trimer interface [polypeptide binding]; other site
1267753000645	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
1267753000646	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753000647	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753000648	homodimer interface [polypeptide binding]; other site
1267753000649	catalytic residue [active]
1267753000650	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1267753000651	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1267753000652	NAD binding site [chemical binding]; other site
1267753000653	dimerization interface [polypeptide binding]; other site
1267753000654	product binding site; other site
1267753000655	substrate binding site [chemical binding]; other site
1267753000656	zinc binding site [ion binding]; other site
1267753000657	catalytic residues [active]
1267753000658	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1267753000659	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1267753000660	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1267753000661	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1267753000662	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1267753000663	putative NAD(P) binding site [chemical binding]; other site
1267753000664	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753000665	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1267753000666	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1267753000667	dimerization interface [polypeptide binding]; other site
1267753000668	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1267753000669	exonuclease I; Provisional; Region: sbcB; PRK11779
1267753000670	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
1267753000671	active site
1267753000672	catalytic site [active]
1267753000673	substrate binding site [chemical binding]; other site
1267753000674	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
1267753000675	SopA-like central domain; Region: SopA; pfam13981
1267753000676	SopA-like catalytic domain; Region: SopA_C; pfam13979
1267753000677	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
1267753000678	thiosulfate reductase PhsA; Provisional; Region: PRK15488
1267753000679	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1267753000680	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
1267753000681	putative [Fe4-S4] binding site [ion binding]; other site
1267753000682	putative molybdopterin cofactor binding site [chemical binding]; other site
1267753000683	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753000684	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
1267753000685	putative molybdopterin cofactor binding site; other site
1267753000686	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1267753000687	4Fe-4S binding domain; Region: Fer4; cl02805
1267753000688	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
1267753000689	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
1267753000690	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
1267753000691	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1267753000692	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1267753000693	DNA gyrase inhibitor; Provisional; Region: PRK10016
1267753000694	Predicted membrane protein [Function unknown]; Region: COG1289
1267753000695	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1267753000696	hypothetical protein; Provisional; Region: PRK05423
1267753000697	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
1267753000698	propionate kinase; Reviewed; Region: PRK12397
1267753000699	propionate/acetate kinase; Provisional; Region: PRK12379
1267753000700	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
1267753000701	G3 box; other site
1267753000702	Switch II region; other site
1267753000703	GTP/Mg2+ binding site [chemical binding]; other site
1267753000704	G4 box; other site
1267753000705	G5 box; other site
1267753000706	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1267753000707	putative hexamer interface [polypeptide binding]; other site
1267753000708	putative hexagonal pore; other site
1267753000709	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1267753000710	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1267753000711	putative hexamer interface [polypeptide binding]; other site
1267753000712	putative hexagonal pore; other site
1267753000713	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1267753000714	putative hexamer interface [polypeptide binding]; other site
1267753000715	putative hexagonal pore; other site
1267753000716	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
1267753000717	SLBB domain; Region: SLBB; pfam10531
1267753000718	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
1267753000719	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
1267753000720	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1267753000721	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
1267753000722	putative active site [active]
1267753000723	metal binding site [ion binding]; metal-binding site
1267753000724	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1267753000725	putative catalytic cysteine [active]
1267753000726	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
1267753000727	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
1267753000728	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1267753000729	Hexamer/Pentamer interface [polypeptide binding]; other site
1267753000730	central pore; other site
1267753000731	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
1267753000732	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1267753000733	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1267753000734	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1267753000735	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1267753000736	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
1267753000737	putative hexamer interface [polypeptide binding]; other site
1267753000738	putative hexagonal pore; other site
1267753000739	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1267753000740	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1267753000741	Hexamer interface [polypeptide binding]; other site
1267753000742	Putative hexagonal pore residue; other site
1267753000743	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
1267753000744	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
1267753000745	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
1267753000746	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
1267753000747	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
1267753000748	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
1267753000749	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
1267753000750	alpha-beta subunit interface [polypeptide binding]; other site
1267753000751	alpha-gamma subunit interface [polypeptide binding]; other site
1267753000752	active site
1267753000753	substrate and K+ binding site; other site
1267753000754	K+ binding site [ion binding]; other site
1267753000755	cobalamin binding site [chemical binding]; other site
1267753000756	propanediol utilization protein PduB; Provisional; Region: PRK15415
1267753000757	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
1267753000758	putative hexamer interface [polypeptide binding]; other site
1267753000759	putative hexagonal pore; other site
1267753000760	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
1267753000761	putative hexamer interface [polypeptide binding]; other site
1267753000762	putative hexagonal pore; other site
1267753000763	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1267753000764	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1267753000765	Hexamer interface [polypeptide binding]; other site
1267753000766	Putative hexagonal pore residue; other site
1267753000767	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1267753000768	amphipathic channel; other site
1267753000769	Asn-Pro-Ala signature motifs; other site
1267753000770	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
1267753000771	Sensory domain found in PocR; Region: PocR; pfam10114
1267753000772	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753000773	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1267753000774	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753000775	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
1267753000776	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1267753000777	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
1267753000778	catalytic triad [active]
1267753000779	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1267753000780	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
1267753000781	Precorrin-8X methylmutase; Region: CbiC; pfam02570
1267753000782	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1267753000783	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1267753000784	active site
1267753000785	putative homodimer interface [polypeptide binding]; other site
1267753000786	SAM binding site [chemical binding]; other site
1267753000787	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
1267753000788	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753000789	S-adenosylmethionine binding site [chemical binding]; other site
1267753000790	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1267753000791	active site
1267753000792	SAM binding site [chemical binding]; other site
1267753000793	homodimer interface [polypeptide binding]; other site
1267753000794	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1267753000795	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1267753000796	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1267753000797	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1267753000798	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1267753000799	active site
1267753000800	SAM binding site [chemical binding]; other site
1267753000801	homodimer interface [polypeptide binding]; other site
1267753000802	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1267753000803	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1267753000804	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
1267753000805	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
1267753000806	active site
1267753000807	C-terminal domain interface [polypeptide binding]; other site
1267753000808	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
1267753000809	active site
1267753000810	N-terminal domain interface [polypeptide binding]; other site
1267753000811	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1267753000812	active site
1267753000813	SAM binding site [chemical binding]; other site
1267753000814	homodimer interface [polypeptide binding]; other site
1267753000815	cobalt transport protein CbiM; Validated; Region: PRK08319
1267753000816	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1267753000817	cobalt transport protein CbiN; Provisional; Region: PRK02898
1267753000818	cobalt transport protein CbiQ; Provisional; Region: PRK15485
1267753000819	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
1267753000820	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1267753000821	Walker A/P-loop; other site
1267753000822	ATP binding site [chemical binding]; other site
1267753000823	Q-loop/lid; other site
1267753000824	ABC transporter signature motif; other site
1267753000825	Walker B; other site
1267753000826	D-loop; other site
1267753000827	H-loop/switch region; other site
1267753000828	cobyric acid synthase; Provisional; Region: PRK00784
1267753000829	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1267753000830	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1267753000831	catalytic triad [active]
1267753000832	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1267753000833	homotrimer interface [polypeptide binding]; other site
1267753000834	Walker A motif; other site
1267753000835	GTP binding site [chemical binding]; other site
1267753000836	Walker B motif; other site
1267753000837	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1267753000838	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1267753000839	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1267753000840	putative dimer interface [polypeptide binding]; other site
1267753000841	active site pocket [active]
1267753000842	putative cataytic base [active]
1267753000843	L,D-transpeptidase; Provisional; Region: PRK10190
1267753000844	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1267753000845	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1267753000846	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1267753000847	catalytic residue [active]
1267753000848	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
1267753000849	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1267753000850	active site
1267753000851	AMP binding site [chemical binding]; other site
1267753000852	acyl-activating enzyme (AAE) consensus motif; other site
1267753000853	CoA binding site [chemical binding]; other site
1267753000854	EamA-like transporter family; Region: EamA; cl17759
1267753000855	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1267753000856	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1267753000857	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1267753000858	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753000859	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753000860	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1267753000861	dimerization interface [polypeptide binding]; other site
1267753000862	potential frameshift: common BLAST hit: gi|283785755|ref|YP_003365620.1| integrase
1267753000863	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1267753000864	dimerization interface [polypeptide binding]; other site
1267753000865	putative DNA binding site [nucleotide binding]; other site
1267753000866	putative Zn2+ binding site [ion binding]; other site
1267753000867	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1267753000868	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1267753000869	active site
1267753000870	Arsenical resistance operon trans-acting repressor ArsD; Region: ArsD; pfam06953
1267753000871	arsenical pump-driving ATPase; Region: arsen_driv_ArsA; TIGR04291
1267753000872	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1267753000873	P loop; other site
1267753000874	Nucleotide binding site [chemical binding]; other site
1267753000875	DTAP/Switch II; other site
1267753000876	Switch I; other site
1267753000877	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1267753000878	P loop; other site
1267753000879	Nucleotide binding site [chemical binding]; other site
1267753000880	DTAP/Switch II; other site
1267753000881	Switch I; other site
1267753000882	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
1267753000883	arsenical-resistance protein; Region: acr3; TIGR00832
1267753000884	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1267753000885	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753000886	potential frameshift: common BLAST hit: gi|386591832|ref|YP_006088232.1| Multi antimicrobial extrusion protein (MATE)
1267753000887	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1267753000888	AMP nucleosidase; Provisional; Region: PRK08292
1267753000889	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
1267753000890	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
1267753000891	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1267753000892	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
1267753000893	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1267753000894	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1267753000895	Catalytic site [active]
1267753000896	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1267753000897	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1267753000898	active site
1267753000899	DNA binding site [nucleotide binding]
1267753000900	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1267753000901	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1267753000902	DNA-binding site [nucleotide binding]; DNA binding site
1267753000903	RNA-binding motif; other site
1267753000904	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1267753000905	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1267753000906	trimer interface [polypeptide binding]; other site
1267753000907	eyelet of channel; other site
1267753000908	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1267753000909	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1267753000910	Zn2+ binding site [ion binding]; other site
1267753000911	Mg2+ binding site [ion binding]; other site
1267753000912	DNA cytosine methylase; Provisional; Region: PRK10458
1267753000913	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1267753000914	cofactor binding site; other site
1267753000915	DNA binding site [nucleotide binding]
1267753000916	substrate interaction site [chemical binding]; other site
1267753000917	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
1267753000918	additional DNA contacts [nucleotide binding]; other site
1267753000919	mismatch recognition site; other site
1267753000920	active site
1267753000921	zinc binding site [ion binding]; other site
1267753000922	DNA intercalation site [nucleotide binding]; other site
1267753000923	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1267753000924	EamA-like transporter family; Region: EamA; pfam00892
1267753000925	EamA-like transporter family; Region: EamA; pfam00892
1267753000926	hypothetical protein; Provisional; Region: PRK10062
1267753000927	Uncharacterized small protein [Function unknown]; Region: COG5475
1267753000928	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
1267753000929	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753000930	metal binding site [ion binding]; metal-binding site
1267753000931	active site
1267753000932	I-site; other site
1267753000933	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
1267753000934	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753000935	active site
1267753000936	motif I; other site
1267753000937	motif II; other site
1267753000938	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
1267753000939	hypothetical protein; Provisional; Region: PRK10708
1267753000940	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
1267753000941	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753000942	DNA binding residues [nucleotide binding]
1267753000943	dimerization interface [polypeptide binding]; other site
1267753000944	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1267753000945	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1267753000946	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1267753000947	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
1267753000948	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
1267753000949	flagellar motor switch protein; Validated; Region: fliN; PRK05698
1267753000950	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1267753000951	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1267753000952	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
1267753000953	flagellar hook-length control protein; Provisional; Region: PRK10118
1267753000954	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
1267753000955	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
1267753000956	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
1267753000957	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
1267753000958	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1267753000959	Walker A motif/ATP binding site; other site
1267753000960	Walker B motif; other site
1267753000961	flagellar assembly protein H; Validated; Region: fliH; PRK05687
1267753000962	Flagellar assembly protein FliH; Region: FliH; pfam02108
1267753000963	flagellar motor switch protein FliG; Region: fliG; TIGR00207
1267753000964	FliG C-terminal domain; Region: FliG_C; pfam01706
1267753000965	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1267753000966	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
1267753000967	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1267753000968	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
1267753000969	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1267753000970	CPxP  motif; other site
1267753000971	putative inner membrane protein; Provisional; Region: PRK11099
1267753000972	Sulphur transport; Region: Sulf_transp; pfam04143
1267753000973	lipoprotein; Provisional; Region: PRK10397
1267753000974	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1267753000975	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1267753000976	active site
1267753000977	Na/Ca binding site [ion binding]; other site
1267753000978	catalytic site [active]
1267753000979	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
1267753000980	flagellar protein FliS; Validated; Region: fliS; PRK05685
1267753000981	flagellar capping protein; Reviewed; Region: fliD; PRK08032
1267753000982	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1267753000983	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1267753000984	flagellin; Validated; Region: PRK08026
1267753000985	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1267753000986	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
1267753000987	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1267753000988	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1267753000989	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1267753000990	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1267753000991	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1267753000992	DNA binding residues [nucleotide binding]
1267753000993	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
1267753000994	cystine transporter subunit; Provisional; Region: PRK11260
1267753000995	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753000996	substrate binding pocket [chemical binding]; other site
1267753000997	membrane-bound complex binding site; other site
1267753000998	hinge residues; other site
1267753000999	D-cysteine desulfhydrase; Validated; Region: PRK03910
1267753001000	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
1267753001001	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753001002	catalytic residue [active]
1267753001003	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1267753001004	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753001005	dimer interface [polypeptide binding]; other site
1267753001006	conserved gate region; other site
1267753001007	putative PBP binding loops; other site
1267753001008	ABC-ATPase subunit interface; other site
1267753001009	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
1267753001010	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1267753001011	Walker A/P-loop; other site
1267753001012	ATP binding site [chemical binding]; other site
1267753001013	Q-loop/lid; other site
1267753001014	ABC transporter signature motif; other site
1267753001015	Walker B; other site
1267753001016	D-loop; other site
1267753001017	H-loop/switch region; other site
1267753001018	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1267753001019	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
1267753001020	Autoinducer binding domain; Region: Autoind_bind; pfam03472
1267753001021	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753001022	DNA binding residues [nucleotide binding]
1267753001023	dimerization interface [polypeptide binding]; other site
1267753001024	hypothetical protein; Provisional; Region: PRK10613
1267753001025	response regulator; Provisional; Region: PRK09483
1267753001026	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753001027	active site
1267753001028	phosphorylation site [posttranslational modification]
1267753001029	intermolecular recognition site; other site
1267753001030	dimerization interface [polypeptide binding]; other site
1267753001031	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753001032	DNA binding residues [nucleotide binding]
1267753001033	dimerization interface [polypeptide binding]; other site
1267753001034	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1267753001035	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1267753001036	GIY-YIG motif/motif A; other site
1267753001037	active site
1267753001038	catalytic site [active]
1267753001039	putative DNA binding site [nucleotide binding]; other site
1267753001040	metal binding site [ion binding]; metal-binding site
1267753001041	UvrB/uvrC motif; Region: UVR; pfam02151
1267753001042	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1267753001043	Helix-hairpin-helix motif; Region: HHH; pfam00633
1267753001044	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
1267753001045	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1267753001046	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1267753001047	NlpC/P60 family; Region: NLPC_P60; cl17555
1267753001048	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
1267753001049	hypothetical protein; Provisional; Region: PRK10396
1267753001050	yecA family protein; Region: ygfB_yecA; TIGR02292
1267753001051	SEC-C motif; Region: SEC-C; pfam02810
1267753001052	tyrosine transporter TyrP; Provisional; Region: PRK15132
1267753001053	aromatic amino acid transport protein; Region: araaP; TIGR00837
1267753001054	probable metal-binding protein; Region: matur_matur; TIGR03853
1267753001055	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1267753001056	Ferritin-like domain; Region: Ferritin; pfam00210
1267753001057	ferroxidase diiron center [ion binding]; other site
1267753001058	YecR-like lipoprotein; Region: YecR; pfam13992
1267753001059	hypothetical protein; Provisional; Region: PRK09273
1267753001060	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
1267753001061	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
1267753001062	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1267753001063	Ferritin-like domain; Region: Ferritin; pfam00210
1267753001064	ferroxidase diiron center [ion binding]; other site
1267753001065	DJ-1 family protein; Region: not_thiJ; TIGR01383
1267753001066	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1267753001067	conserved cys residue [active]
1267753001068	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
1267753001069	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
1267753001070	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
1267753001071	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
1267753001072	active site
1267753001073	homotetramer interface [polypeptide binding]; other site
1267753001074	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1267753001075	Ligand Binding Site [chemical binding]; other site
1267753001076	transcriptional activator FlhD; Provisional; Region: PRK02909
1267753001077	transcriptional activator FlhC; Provisional; Region: PRK12722
1267753001078	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1267753001079	flagellar motor protein MotA; Validated; Region: PRK09110
1267753001080	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1267753001081	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1267753001082	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1267753001083	ligand binding site [chemical binding]; other site
1267753001084	chemotaxis protein CheA; Provisional; Region: PRK10547
1267753001085	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1267753001086	putative binding surface; other site
1267753001087	active site
1267753001088	CheY binding; Region: CheY-binding; pfam09078
1267753001089	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1267753001090	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753001091	ATP binding site [chemical binding]; other site
1267753001092	Mg2+ binding site [ion binding]; other site
1267753001093	G-X-G motif; other site
1267753001094	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1267753001095	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1267753001096	putative CheA interaction surface; other site
1267753001097	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1267753001098	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1267753001099	dimer interface [polypeptide binding]; other site
1267753001100	ligand binding site [chemical binding]; other site
1267753001101	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753001102	dimerization interface [polypeptide binding]; other site
1267753001103	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1267753001104	dimer interface [polypeptide binding]; other site
1267753001105	putative CheW interface [polypeptide binding]; other site
1267753001106	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
1267753001107	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1267753001108	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753001109	S-adenosylmethionine binding site [chemical binding]; other site
1267753001110	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1267753001111	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753001112	active site
1267753001113	phosphorylation site [posttranslational modification]
1267753001114	intermolecular recognition site; other site
1267753001115	dimerization interface [polypeptide binding]; other site
1267753001116	CheB methylesterase; Region: CheB_methylest; pfam01339
1267753001117	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1267753001118	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753001119	active site
1267753001120	phosphorylation site [posttranslational modification]
1267753001121	intermolecular recognition site; other site
1267753001122	dimerization interface [polypeptide binding]; other site
1267753001123	chemotaxis regulator CheZ; Provisional; Region: PRK11166
1267753001124	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1267753001125	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1267753001126	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1267753001127	FHIPEP family; Region: FHIPEP; pfam00771
1267753001128	Flagellar protein FlhE; Region: FlhE; pfam06366
1267753001129	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1267753001130	penicillin-binding protein 2; Provisional; Region: PRK10795
1267753001131	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1267753001132	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1267753001133	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1267753001134	arginyl-tRNA synthetase; Region: argS; TIGR00456
1267753001135	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1267753001136	active site
1267753001137	HIGH motif; other site
1267753001138	KMSK motif region; other site
1267753001139	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1267753001140	tRNA binding surface [nucleotide binding]; other site
1267753001141	anticodon binding site; other site
1267753001142	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
1267753001143	putative metal binding site [ion binding]; other site
1267753001144	copper homeostasis protein CutC; Provisional; Region: PRK11572
1267753001145	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753001146	S-adenosylmethionine binding site [chemical binding]; other site
1267753001147	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753001148	S-adenosylmethionine binding site [chemical binding]; other site
1267753001149	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
1267753001150	hypothetical protein; Provisional; Region: PRK10302
1267753001151	Isochorismatase family; Region: Isochorismatase; pfam00857
1267753001152	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1267753001153	catalytic triad [active]
1267753001154	conserved cis-peptide bond; other site
1267753001155	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1267753001156	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1267753001157	dimer interface [polypeptide binding]; other site
1267753001158	anticodon binding site; other site
1267753001159	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1267753001160	homodimer interface [polypeptide binding]; other site
1267753001161	motif 1; other site
1267753001162	active site
1267753001163	motif 2; other site
1267753001164	GAD domain; Region: GAD; pfam02938
1267753001165	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1267753001166	active site
1267753001167	motif 3; other site
1267753001168	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
1267753001169	nudix motif; other site
1267753001170	hypothetical protein; Validated; Region: PRK00110
1267753001171	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1267753001172	active site
1267753001173	putative DNA-binding cleft [nucleotide binding]; other site
1267753001174	dimer interface [polypeptide binding]; other site
1267753001175	hypothetical protein; Provisional; Region: PRK11470
1267753001176	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1267753001177	RuvA N terminal domain; Region: RuvA_N; pfam01330
1267753001178	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1267753001179	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1267753001180	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753001181	Walker A motif; other site
1267753001182	ATP binding site [chemical binding]; other site
1267753001183	Walker B motif; other site
1267753001184	arginine finger; other site
1267753001185	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1267753001186	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1267753001187	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1267753001188	ABC-ATPase subunit  interface; other site
1267753001189	dimer interface [polypeptide binding]; other site
1267753001190	putative PBP binding regions; other site
1267753001191	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
1267753001192	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1267753001193	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
1267753001194	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
1267753001195	metal binding site [ion binding]; metal-binding site
1267753001196	putative peptidase; Provisional; Region: PRK11649
1267753001197	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
1267753001198	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1267753001199	Peptidase family M23; Region: Peptidase_M23; pfam01551
1267753001200	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1267753001201	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1267753001202	putative acyl-acceptor binding pocket; other site
1267753001203	pyruvate kinase; Provisional; Region: PRK05826
1267753001204	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1267753001205	domain interfaces; other site
1267753001206	active site
1267753001207	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
1267753001208	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1267753001209	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1267753001210	putative active site [active]
1267753001211	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1267753001212	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1267753001213	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1267753001214	phosphogluconate dehydratase; Validated; Region: PRK09054
1267753001215	6-phosphogluconate dehydratase; Region: edd; TIGR01196
1267753001216	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
1267753001217	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1267753001218	active site
1267753001219	intersubunit interface [polypeptide binding]; other site
1267753001220	catalytic residue [active]
1267753001221	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1267753001222	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1267753001223	ATP-grasp domain; Region: ATP-grasp; pfam02222
1267753001224	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
1267753001225	hypothetical protein; Provisional; Region: PRK13680
1267753001226	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
1267753001227	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
1267753001228	putative metal binding site [ion binding]; other site
1267753001229	protease 2; Provisional; Region: PRK10115
1267753001230	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1267753001231	exodeoxyribonuclease X; Provisional; Region: PRK07983
1267753001232	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1267753001233	active site
1267753001234	catalytic site [active]
1267753001235	substrate binding site [chemical binding]; other site
1267753001236	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1267753001237	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
1267753001238	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
1267753001239	hypothetical protein; Provisional; Region: PRK10301
1267753001240	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
1267753001241	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1267753001242	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
1267753001243	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
1267753001244	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753001245	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
1267753001246	dimer interface [polypeptide binding]; other site
1267753001247	active site
1267753001248	Int/Topo IB signature motif; other site
1267753001249	exonuclease VIII; Reviewed; Region: PRK09709
1267753001250	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
1267753001251	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
1267753001252	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1267753001253	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1267753001254	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1267753001255	Phage Tail Collar Domain; Region: Collar; pfam07484
1267753001256	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1267753001257	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1267753001258	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1267753001259	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1267753001260	EamA-like transporter family; Region: EamA; pfam00892
1267753001261	EamA-like transporter family; Region: EamA; pfam00892
1267753001262	Fimbrial protein; Region: Fimbrial; cl01416
1267753001263	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1267753001264	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1267753001265	MULE transposase domain; Region: MULE; pfam10551
1267753001266	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
1267753001267	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753001268	Coenzyme A binding pocket [chemical binding]; other site
1267753001269	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
1267753001270	type III secretion protein SopE2; Provisional; Region: PRK15280
1267753001271	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
1267753001272	SopE GEF domain; Region: SopE_GEF; pfam07487
1267753001273	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
1267753001274	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1267753001275	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
1267753001276	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
1267753001277	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1267753001278	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
1267753001279	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1267753001280	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
1267753001281	mce related protein; Region: MCE; pfam02470
1267753001282	mce related protein; Region: MCE; pfam02470
1267753001283	mce related protein; Region: MCE; pfam02470
1267753001284	mce related protein; Region: MCE; pfam02470
1267753001285	mce related protein; Region: MCE; pfam02470
1267753001286	mce related protein; Region: MCE; pfam02470
1267753001287	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
1267753001288	Paraquat-inducible protein A; Region: PqiA; pfam04403
1267753001289	Paraquat-inducible protein A; Region: PqiA; pfam04403
1267753001290	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1267753001291	GAF domain; Region: GAF_2; pfam13185
1267753001292	ProP expression regulator; Provisional; Region: PRK04950
1267753001293	ProQ/FINO family; Region: ProQ; pfam04352
1267753001294	carboxy-terminal protease; Provisional; Region: PRK11186
1267753001295	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1267753001296	protein binding site [polypeptide binding]; other site
1267753001297	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1267753001298	Catalytic dyad [active]
1267753001299	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1267753001300	heat shock protein HtpX; Provisional; Region: PRK05457
1267753001301	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753001302	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1267753001303	putative substrate translocation pore; other site
1267753001304	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753001305	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
1267753001306	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1267753001307	dimerization interface [polypeptide binding]; other site
1267753001308	putative Zn2+ binding site [ion binding]; other site
1267753001309	putative DNA binding site [nucleotide binding]; other site
1267753001310	Bacterial transcriptional regulator; Region: IclR; pfam01614
1267753001311	YobH-like protein; Region: YobH; pfam13996
1267753001312	PhoPQ regulatory protein; Provisional; Region: PRK10299
1267753001313	YebO-like protein; Region: YebO; pfam13974
1267753001314	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
1267753001315	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1267753001316	DNA-binding site [nucleotide binding]; DNA binding site
1267753001317	RNA-binding motif; other site
1267753001318	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1267753001319	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1267753001320	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1267753001321	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
1267753001322	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753001323	S-adenosylmethionine binding site [chemical binding]; other site
1267753001324	hypothetical protein; Provisional; Region: PRK11469
1267753001325	Domain of unknown function DUF; Region: DUF204; pfam02659
1267753001326	Domain of unknown function DUF; Region: DUF204; pfam02659
1267753001327	hypothetical protein; Provisional; Region: PRK02913
1267753001328	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
1267753001329	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
1267753001330	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1267753001331	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1267753001332	active pocket/dimerization site; other site
1267753001333	active site
1267753001334	phosphorylation site [posttranslational modification]
1267753001335	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1267753001336	active site
1267753001337	phosphorylation site [posttranslational modification]
1267753001338	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1267753001339	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1267753001340	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1267753001341	Transporter associated domain; Region: CorC_HlyC; smart01091
1267753001342	phage resistance protein; Provisional; Region: PRK10551
1267753001343	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1267753001344	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753001345	L-serine deaminase; Provisional; Region: PRK15023
1267753001346	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1267753001347	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1267753001348	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1267753001349	putative active site [active]
1267753001350	putative CoA binding site [chemical binding]; other site
1267753001351	nudix motif; other site
1267753001352	metal binding site [ion binding]; metal-binding site
1267753001353	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
1267753001354	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1267753001355	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
1267753001356	hypothetical protein; Provisional; Region: PRK05114
1267753001357	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1267753001358	homotrimer interaction site [polypeptide binding]; other site
1267753001359	putative active site [active]
1267753001360	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
1267753001361	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1267753001362	DEAD_2; Region: DEAD_2; pfam06733
1267753001363	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1267753001364	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1267753001365	Glycoprotease family; Region: Peptidase_M22; pfam00814
1267753001366	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
1267753001367	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
1267753001368	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1267753001369	acyl-activating enzyme (AAE) consensus motif; other site
1267753001370	putative AMP binding site [chemical binding]; other site
1267753001371	putative active site [active]
1267753001372	putative CoA binding site [chemical binding]; other site
1267753001373	ribonuclease D; Provisional; Region: PRK10829
1267753001374	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
1267753001375	catalytic site [active]
1267753001376	putative active site [active]
1267753001377	putative substrate binding site [chemical binding]; other site
1267753001378	HRDC domain; Region: HRDC; cl02578
1267753001379	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
1267753001380	cell division inhibitor MinD; Provisional; Region: PRK10818
1267753001381	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1267753001382	Switch I; other site
1267753001383	Switch II; other site
1267753001384	septum formation inhibitor; Reviewed; Region: minC; PRK03511
1267753001385	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1267753001386	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1267753001387	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
1267753001388	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1267753001389	hypothetical protein; Provisional; Region: PRK10691
1267753001390	hypothetical protein; Provisional; Region: PRK05170
1267753001391	GnsA/GnsB family; Region: GnsAB; pfam08178
1267753001392	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1267753001393	disulfide bond formation protein B; Provisional; Region: PRK01749
1267753001394	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1267753001395	transmembrane helices; other site
1267753001396	fatty acid metabolism regulator; Provisional; Region: PRK04984
1267753001397	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753001398	DNA-binding site [nucleotide binding]; DNA binding site
1267753001399	FadR C-terminal domain; Region: FadR_C; pfam07840
1267753001400	SpoVR family protein; Provisional; Region: PRK11767
1267753001401	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
1267753001402	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
1267753001403	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1267753001404	alanine racemase; Reviewed; Region: dadX; PRK03646
1267753001405	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1267753001406	active site
1267753001407	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1267753001408	substrate binding site [chemical binding]; other site
1267753001409	catalytic residues [active]
1267753001410	dimer interface [polypeptide binding]; other site
1267753001411	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
1267753001412	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1267753001413	TrkA-C domain; Region: TrkA_C; pfam02080
1267753001414	Transporter associated domain; Region: CorC_HlyC; smart01091
1267753001415	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1267753001416	dimer interface [polypeptide binding]; other site
1267753001417	catalytic triad [active]
1267753001418	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
1267753001419	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1267753001420	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1267753001421	catalytic residue [active]
1267753001422	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1267753001423	Flagellar regulator YcgR; Region: YcgR; pfam07317
1267753001424	PilZ domain; Region: PilZ; pfam07238
1267753001425	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
1267753001426	trehalase; Provisional; Region: treA; PRK13271
1267753001427	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1267753001428	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1267753001429	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1267753001430	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1267753001431	NAD(P) binding site [chemical binding]; other site
1267753001432	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
1267753001433	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
1267753001434	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1267753001435	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
1267753001436	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1267753001437	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1267753001438	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1267753001439	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1267753001440	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1267753001441	putative substrate-binding site; other site
1267753001442	nickel binding site [ion binding]; other site
1267753001443	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
1267753001444	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1267753001445	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1267753001446	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
1267753001447	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1267753001448	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1267753001449	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
1267753001450	Protein of unknown function (DUF4427); Region: DUF4427; pfam14468
1267753001451	GTP-binding protein YchF; Reviewed; Region: PRK09601
1267753001452	YchF GTPase; Region: YchF; cd01900
1267753001453	G1 box; other site
1267753001454	GTP/Mg2+ binding site [chemical binding]; other site
1267753001455	Switch I region; other site
1267753001456	G2 box; other site
1267753001457	Switch II region; other site
1267753001458	G3 box; other site
1267753001459	G4 box; other site
1267753001460	G5 box; other site
1267753001461	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1267753001462	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1267753001463	putative active site [active]
1267753001464	catalytic residue [active]
1267753001465	hypothetical protein; Provisional; Region: PRK10692
1267753001466	putative transporter; Provisional; Region: PRK11660
1267753001467	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1267753001468	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1267753001469	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1267753001470	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1267753001471	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1267753001472	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1267753001473	active site
1267753001474	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
1267753001475	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1267753001476	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
1267753001477	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
1267753001478	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1267753001479	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1267753001480	tRNA; other site
1267753001481	putative tRNA binding site [nucleotide binding]; other site
1267753001482	putative NADP binding site [chemical binding]; other site
1267753001483	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1267753001484	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1267753001485	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1267753001486	RF-1 domain; Region: RF-1; pfam00472
1267753001487	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1267753001488	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753001489	hypothetical protein; Provisional; Region: PRK10278
1267753001490	hypothetical protein; Provisional; Region: PRK10941
1267753001491	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
1267753001492	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
1267753001493	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1267753001494	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
1267753001495	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1267753001496	cation transport regulator; Reviewed; Region: chaB; PRK09582
1267753001497	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
1267753001498	putative invasin; Provisional; Region: PRK10177
1267753001499	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1267753001500	transcriptional regulator NarL; Provisional; Region: PRK10651
1267753001501	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753001502	active site
1267753001503	phosphorylation site [posttranslational modification]
1267753001504	intermolecular recognition site; other site
1267753001505	dimerization interface [polypeptide binding]; other site
1267753001506	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753001507	DNA binding residues [nucleotide binding]
1267753001508	dimerization interface [polypeptide binding]; other site
1267753001509	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
1267753001510	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1267753001511	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753001512	dimerization interface [polypeptide binding]; other site
1267753001513	Histidine kinase; Region: HisKA_3; pfam07730
1267753001514	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753001515	ATP binding site [chemical binding]; other site
1267753001516	Mg2+ binding site [ion binding]; other site
1267753001517	G-X-G motif; other site
1267753001518	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1267753001519	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
1267753001520	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1267753001521	[4Fe-4S] binding site [ion binding]; other site
1267753001522	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753001523	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753001524	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753001525	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1267753001526	molybdopterin cofactor binding site; other site
1267753001527	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1267753001528	4Fe-4S binding domain; Region: Fer4; cl02805
1267753001529	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1267753001530	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1267753001531	potential protein location (hypothetical protein CFSAN001992_02675 [Salmonella enterica subsp. enterica serovar Javiana str. CFSAN001992]) that overlaps RNA (tRNA-Y)
1267753001532	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
1267753001533	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1267753001534	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1267753001535	putative active site [active]
1267753001536	putative substrate binding site [chemical binding]; other site
1267753001537	putative cosubstrate binding site; other site
1267753001538	catalytic site [active]
1267753001539	SEC-C motif; Region: SEC-C; pfam02810
1267753001540	hypothetical protein; Provisional; Region: PRK04233
1267753001541	hypothetical protein; Provisional; Region: PRK10279
1267753001542	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
1267753001543	active site
1267753001544	nucleophile elbow; other site
1267753001545	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753001546	active site
1267753001547	response regulator of RpoS; Provisional; Region: PRK10693
1267753001548	phosphorylation site [posttranslational modification]
1267753001549	intermolecular recognition site; other site
1267753001550	dimerization interface [polypeptide binding]; other site
1267753001551	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1267753001552	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1267753001553	active site
1267753001554	tetramer interface; other site
1267753001555	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
1267753001556	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1267753001557	thymidine kinase; Provisional; Region: PRK04296
1267753001558	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1267753001559	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1267753001560	putative catalytic cysteine [active]
1267753001561	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1267753001562	putative active site [active]
1267753001563	metal binding site [ion binding]; metal-binding site
1267753001564	hypothetical protein; Provisional; Region: PRK11111
1267753001565	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1267753001566	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1267753001567	peptide binding site [polypeptide binding]; other site
1267753001568	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
1267753001569	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753001570	dimer interface [polypeptide binding]; other site
1267753001571	conserved gate region; other site
1267753001572	putative PBP binding loops; other site
1267753001573	ABC-ATPase subunit interface; other site
1267753001574	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1267753001575	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1267753001576	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753001577	dimer interface [polypeptide binding]; other site
1267753001578	conserved gate region; other site
1267753001579	ABC-ATPase subunit interface; other site
1267753001580	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
1267753001581	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753001582	Walker A/P-loop; other site
1267753001583	ATP binding site [chemical binding]; other site
1267753001584	Q-loop/lid; other site
1267753001585	ABC transporter signature motif; other site
1267753001586	Walker B; other site
1267753001587	D-loop; other site
1267753001588	H-loop/switch region; other site
1267753001589	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1267753001590	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1267753001591	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753001592	Walker A/P-loop; other site
1267753001593	ATP binding site [chemical binding]; other site
1267753001594	Q-loop/lid; other site
1267753001595	ABC transporter signature motif; other site
1267753001596	Walker B; other site
1267753001597	D-loop; other site
1267753001598	H-loop/switch region; other site
1267753001599	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1267753001600	Ion transport protein; Region: Ion_trans; pfam00520
1267753001601	Ion channel; Region: Ion_trans_2; pfam07885
1267753001602	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1267753001603	Double zinc ribbon; Region: DZR; pfam12773
1267753001604	dsDNA-mimic protein; Reviewed; Region: PRK05094
1267753001605	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1267753001606	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1267753001607	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
1267753001608	putative active site [active]
1267753001609	catalytic site [active]
1267753001610	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
1267753001611	putative active site [active]
1267753001612	catalytic site [active]
1267753001613	YciI-like protein; Reviewed; Region: PRK11370
1267753001614	transport protein TonB; Provisional; Region: PRK10819
1267753001615	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1267753001616	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1267753001617	intracellular septation protein A; Reviewed; Region: PRK00259
1267753001618	hypothetical protein; Provisional; Region: PRK02868
1267753001619	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1267753001620	outer membrane protein W; Provisional; Region: PRK10959
1267753001621	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1267753001622	dimanganese center [ion binding]; other site
1267753001623	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1267753001624	dinuclear metal binding motif [ion binding]; other site
1267753001625	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
1267753001626	dimerization interface [polypeptide binding]; other site
1267753001627	metal binding site [ion binding]; metal-binding site
1267753001628	General stress protein [General function prediction only]; Region: GsiB; COG3729
1267753001629	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1267753001630	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1267753001631	substrate binding site [chemical binding]; other site
1267753001632	active site
1267753001633	catalytic residues [active]
1267753001634	heterodimer interface [polypeptide binding]; other site
1267753001635	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1267753001636	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1267753001637	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753001638	catalytic residue [active]
1267753001639	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
1267753001640	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1267753001641	active site
1267753001642	ribulose/triose binding site [chemical binding]; other site
1267753001643	phosphate binding site [ion binding]; other site
1267753001644	substrate (anthranilate) binding pocket [chemical binding]; other site
1267753001645	product (indole) binding pocket [chemical binding]; other site
1267753001646	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1267753001647	active site
1267753001648	anthranilate synthase component I; Provisional; Region: PRK13564
1267753001649	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1267753001650	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1267753001651	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1267753001652	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1267753001653	active site
1267753001654	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1267753001655	hypothetical protein; Provisional; Region: PRK11630
1267753001656	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
1267753001657	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1267753001658	RNA binding surface [nucleotide binding]; other site
1267753001659	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
1267753001660	probable active site [active]
1267753001661	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
1267753001662	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
1267753001663	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
1267753001664	homodimer interface [polypeptide binding]; other site
1267753001665	Walker A motif; other site
1267753001666	ATP binding site [chemical binding]; other site
1267753001667	hydroxycobalamin binding site [chemical binding]; other site
1267753001668	Walker B motif; other site
1267753001669	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
1267753001670	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
1267753001671	NADP binding site [chemical binding]; other site
1267753001672	homodimer interface [polypeptide binding]; other site
1267753001673	active site
1267753001674	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
1267753001675	putative inner membrane peptidase; Provisional; Region: PRK11778
1267753001676	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1267753001677	tandem repeat interface [polypeptide binding]; other site
1267753001678	oligomer interface [polypeptide binding]; other site
1267753001679	active site residues [active]
1267753001680	hypothetical protein; Provisional; Region: PRK11037
1267753001681	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
1267753001682	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753001683	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
1267753001684	substrate binding site [chemical binding]; other site
1267753001685	putative dimerization interface [polypeptide binding]; other site
1267753001686	aconitate hydratase; Validated; Region: PRK09277
1267753001687	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1267753001688	substrate binding site [chemical binding]; other site
1267753001689	ligand binding site [chemical binding]; other site
1267753001690	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1267753001691	substrate binding site [chemical binding]; other site
1267753001692	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1267753001693	dimerization interface [polypeptide binding]; other site
1267753001694	active site
1267753001695	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1267753001696	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1267753001697	active site
1267753001698	Predicted membrane protein [Function unknown]; Region: COG3771
1267753001699	tetratricopeptide repeat protein; Provisional; Region: PRK11788
1267753001700	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1267753001701	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1267753001702	active site
1267753001703	dimer interface [polypeptide binding]; other site
1267753001704	translation initiation factor Sui1; Validated; Region: PRK06824
1267753001705	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1267753001706	putative rRNA binding site [nucleotide binding]; other site
1267753001707	lipoprotein; Provisional; Region: PRK10540
1267753001708	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753001709	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1267753001710	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753001711	hypothetical protein; Provisional; Region: PRK13658
1267753001712	RNase II stability modulator; Provisional; Region: PRK10060
1267753001713	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1267753001714	putative active site [active]
1267753001715	heme pocket [chemical binding]; other site
1267753001716	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753001717	metal binding site [ion binding]; metal-binding site
1267753001718	active site
1267753001719	I-site; other site
1267753001720	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753001721	exoribonuclease II; Provisional; Region: PRK05054
1267753001722	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1267753001723	RNB domain; Region: RNB; pfam00773
1267753001724	S1 RNA binding domain; Region: S1; pfam00575
1267753001725	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
1267753001726	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1267753001727	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
1267753001728	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1267753001729	NAD binding site [chemical binding]; other site
1267753001730	homotetramer interface [polypeptide binding]; other site
1267753001731	homodimer interface [polypeptide binding]; other site
1267753001732	substrate binding site [chemical binding]; other site
1267753001733	active site
1267753001734	Protein kinase domain; Region: Pkinase; pfam00069
1267753001735	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1267753001736	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
1267753001737	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753001738	Walker A/P-loop; other site
1267753001739	ATP binding site [chemical binding]; other site
1267753001740	Q-loop/lid; other site
1267753001741	ABC transporter signature motif; other site
1267753001742	Walker B; other site
1267753001743	D-loop; other site
1267753001744	H-loop/switch region; other site
1267753001745	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
1267753001746	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753001747	Walker A/P-loop; other site
1267753001748	ATP binding site [chemical binding]; other site
1267753001749	Q-loop/lid; other site
1267753001750	ABC transporter signature motif; other site
1267753001751	Walker B; other site
1267753001752	D-loop; other site
1267753001753	H-loop/switch region; other site
1267753001754	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1267753001755	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
1267753001756	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1267753001757	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753001758	dimer interface [polypeptide binding]; other site
1267753001759	conserved gate region; other site
1267753001760	putative PBP binding loops; other site
1267753001761	ABC-ATPase subunit interface; other site
1267753001762	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
1267753001763	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1267753001764	Pertussis toxin, subunit 1; Region: Pertussis_S1; cl03779
1267753001765	subtilase cytotoxin subunit B-like protein; Provisional; Region: PRK15265; cl14664
1267753001766	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1267753001767	Resolvase, N terminal domain; Region: Resolvase; pfam00239
1267753001768	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
1267753001769	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753001770	dimer interface [polypeptide binding]; other site
1267753001771	conserved gate region; other site
1267753001772	putative PBP binding loops; other site
1267753001773	ABC-ATPase subunit interface; other site
1267753001774	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1267753001775	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1267753001776	peptide binding site [polypeptide binding]; other site
1267753001777	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
1267753001778	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753001779	Walker A motif; other site
1267753001780	ATP binding site [chemical binding]; other site
1267753001781	Walker B motif; other site
1267753001782	arginine finger; other site
1267753001783	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
1267753001784	phage shock protein PspA; Provisional; Region: PRK10698
1267753001785	phage shock protein B; Provisional; Region: pspB; PRK09458
1267753001786	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
1267753001787	phage shock protein C; Region: phageshock_pspC; TIGR02978
1267753001788	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
1267753001789	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1267753001790	active site residue [active]
1267753001791	Predicted ATPase [General function prediction only]; Region: COG3106
1267753001792	hypothetical protein; Provisional; Region: PRK05415
1267753001793	TIGR01620 family protein; Region: hyp_HI0043
1267753001794	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
1267753001795	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
1267753001796	putative aromatic amino acid binding site; other site
1267753001797	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753001798	Walker A motif; other site
1267753001799	ATP binding site [chemical binding]; other site
1267753001800	Walker B motif; other site
1267753001801	arginine finger; other site
1267753001802	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1267753001803	dimer interface [polypeptide binding]; other site
1267753001804	catalytic triad [active]
1267753001805	peroxidatic and resolving cysteines [active]
1267753001806	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
1267753001807	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
1267753001808	active site
1267753001809	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
1267753001810	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
1267753001811	putative active site [active]
1267753001812	Zn binding site [ion binding]; other site
1267753001813	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
1267753001814	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1267753001815	peptide binding site [polypeptide binding]; other site
1267753001816	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
1267753001817	NmrA-like family; Region: NmrA; pfam05368
1267753001818	NAD(P) binding site [chemical binding]; other site
1267753001819	active site lysine
1267753001820	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753001821	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753001822	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1267753001823	putative effector binding pocket; other site
1267753001824	putative dimerization interface [polypeptide binding]; other site
1267753001825	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1267753001826	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1267753001827	active site
1267753001828	catalytic tetrad [active]
1267753001829	oxidoreductase; Provisional; Region: PRK12742
1267753001830	classical (c) SDRs; Region: SDR_c; cd05233
1267753001831	NAD(P) binding site [chemical binding]; other site
1267753001832	active site
1267753001833	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1267753001834	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753001835	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1267753001836	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1267753001837	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753001838	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1267753001839	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1267753001840	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1267753001841	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
1267753001842	B3/4 domain; Region: B3_4; pfam03483
1267753001843	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1267753001844	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753001845	non-specific DNA binding site [nucleotide binding]; other site
1267753001846	salt bridge; other site
1267753001847	sequence-specific DNA binding site [nucleotide binding]; other site
1267753001848	Cupin domain; Region: Cupin_2; pfam07883
1267753001849	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1267753001850	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1267753001851	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
1267753001852	universal stress protein UspE; Provisional; Region: PRK11175
1267753001853	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1267753001854	Ligand Binding Site [chemical binding]; other site
1267753001855	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1267753001856	Ligand Binding Site [chemical binding]; other site
1267753001857	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
1267753001858	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1267753001859	ligand binding site [chemical binding]; other site
1267753001860	flexible hinge region; other site
1267753001861	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1267753001862	putative switch regulator; other site
1267753001863	non-specific DNA interactions [nucleotide binding]; other site
1267753001864	DNA binding site [nucleotide binding]
1267753001865	sequence specific DNA binding site [nucleotide binding]; other site
1267753001866	putative cAMP binding site [chemical binding]; other site
1267753001867	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
1267753001868	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1267753001869	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1267753001870	DNA binding site [nucleotide binding]
1267753001871	active site
1267753001872	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
1267753001873	Smr domain; Region: Smr; pfam01713
1267753001874	HAMP domain; Region: HAMP; pfam00672
1267753001875	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1267753001876	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1267753001877	dimer interface [polypeptide binding]; other site
1267753001878	putative CheW interface [polypeptide binding]; other site
1267753001879	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1267753001880	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
1267753001881	Cl binding site [ion binding]; other site
1267753001882	oligomer interface [polypeptide binding]; other site
1267753001883	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1267753001884	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1267753001885	ATP binding site [chemical binding]; other site
1267753001886	Mg++ binding site [ion binding]; other site
1267753001887	motif III; other site
1267753001888	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753001889	nucleotide binding region [chemical binding]; other site
1267753001890	ATP-binding site [chemical binding]; other site
1267753001891	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
1267753001892	putative RNA binding site [nucleotide binding]; other site
1267753001893	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1267753001894	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1267753001895	Ligand Binding Site [chemical binding]; other site
1267753001896	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753001897	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1267753001898	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1267753001899	Ligand Binding Site [chemical binding]; other site
1267753001900	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1267753001901	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1267753001902	dimer interface [polypeptide binding]; other site
1267753001903	PYR/PP interface [polypeptide binding]; other site
1267753001904	TPP binding site [chemical binding]; other site
1267753001905	substrate binding site [chemical binding]; other site
1267753001906	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1267753001907	Domain of unknown function; Region: EKR; smart00890
1267753001908	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1267753001909	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753001910	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1267753001911	TPP-binding site [chemical binding]; other site
1267753001912	dimer interface [polypeptide binding]; other site
1267753001913	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1267753001914	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1267753001915	heat-inducible protein; Provisional; Region: PRK10449
1267753001916	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1267753001917	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1267753001918	putative ligand binding site [chemical binding]; other site
1267753001919	putative NAD binding site [chemical binding]; other site
1267753001920	catalytic site [active]
1267753001921	hypothetical protein; Provisional; Region: PRK10695
1267753001922	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
1267753001923	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
1267753001924	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1267753001925	azoreductase; Reviewed; Region: PRK00170
1267753001926	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1267753001927	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
1267753001928	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753001929	ATP binding site [chemical binding]; other site
1267753001930	putative Mg++ binding site [ion binding]; other site
1267753001931	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753001932	nucleotide binding region [chemical binding]; other site
1267753001933	ATP-binding site [chemical binding]; other site
1267753001934	Helicase associated domain (HA2); Region: HA2; pfam04408
1267753001935	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
1267753001936	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
1267753001937	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1267753001938	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1267753001939	putative active site [active]
1267753001940	cytochrome b561; Provisional; Region: PRK11513
1267753001941	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753001942	S-adenosylmethionine binding site [chemical binding]; other site
1267753001943	Predicted membrane protein [Function unknown]; Region: COG5305
1267753001944	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1267753001945	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753001946	dimer interface [polypeptide binding]; other site
1267753001947	conserved gate region; other site
1267753001948	putative PBP binding loops; other site
1267753001949	ABC-ATPase subunit interface; other site
1267753001950	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1267753001951	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753001952	Walker A/P-loop; other site
1267753001953	ATP binding site [chemical binding]; other site
1267753001954	Q-loop/lid; other site
1267753001955	ABC transporter signature motif; other site
1267753001956	Walker B; other site
1267753001957	D-loop; other site
1267753001958	H-loop/switch region; other site
1267753001959	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1267753001960	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753001961	dimer interface [polypeptide binding]; other site
1267753001962	conserved gate region; other site
1267753001963	putative PBP binding loops; other site
1267753001964	ABC-ATPase subunit interface; other site
1267753001965	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753001966	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1267753001967	substrate binding pocket [chemical binding]; other site
1267753001968	membrane-bound complex binding site; other site
1267753001969	hinge residues; other site
1267753001970	Predicted membrane protein [Function unknown]; Region: COG3326
1267753001971	Sif protein; Region: Sif; cl11505
1267753001972	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1267753001973	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
1267753001974	active site
1267753001975	catalytic triad [active]
1267753001976	oxyanion hole [active]
1267753001977	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1267753001978	putative metal binding site [ion binding]; other site
1267753001979	putative homodimer interface [polypeptide binding]; other site
1267753001980	putative homotetramer interface [polypeptide binding]; other site
1267753001981	putative homodimer-homodimer interface [polypeptide binding]; other site
1267753001982	putative allosteric switch controlling residues; other site
1267753001983	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
1267753001984	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
1267753001985	substrate binding site [chemical binding]; other site
1267753001986	catalytic Zn binding site [ion binding]; other site
1267753001987	NAD binding site [chemical binding]; other site
1267753001988	structural Zn binding site [ion binding]; other site
1267753001989	dimer interface [polypeptide binding]; other site
1267753001990	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1267753001991	dimer interface [polypeptide binding]; other site
1267753001992	ligand binding site [chemical binding]; other site
1267753001993	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1267753001994	HAMP domain; Region: HAMP; pfam00672
1267753001995	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1267753001996	dimer interface [polypeptide binding]; other site
1267753001997	putative CheW interface [polypeptide binding]; other site
1267753001998	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
1267753001999	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753002000	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1267753002001	dimerization interface [polypeptide binding]; other site
1267753002002	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1267753002003	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
1267753002004	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
1267753002005	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1267753002006	substrate binding pocket [chemical binding]; other site
1267753002007	catalytic triad [active]
1267753002008	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
1267753002009	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
1267753002010	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1267753002011	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
1267753002012	teramer interface [polypeptide binding]; other site
1267753002013	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
1267753002014	active site
1267753002015	FMN binding site [chemical binding]; other site
1267753002016	catalytic residues [active]
1267753002017	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753002018	Coenzyme A binding pocket [chemical binding]; other site
1267753002019	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753002020	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1267753002021	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753002022	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1267753002023	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1267753002024	substrate binding site [chemical binding]; other site
1267753002025	hexamer interface [polypeptide binding]; other site
1267753002026	metal binding site [ion binding]; metal-binding site
1267753002027	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753002028	active site
1267753002029	phosphorylation site [posttranslational modification]
1267753002030	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
1267753002031	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1267753002032	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
1267753002033	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1267753002034	active site
1267753002035	P-loop; other site
1267753002036	phosphorylation site [posttranslational modification]
1267753002037	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1267753002038	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1267753002039	oligomer interface [polypeptide binding]; other site
1267753002040	active site
1267753002041	metal binding site [ion binding]; metal-binding site
1267753002042	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1267753002043	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753002044	Coenzyme A binding pocket [chemical binding]; other site
1267753002045	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1267753002046	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1267753002047	putative trimer interface [polypeptide binding]; other site
1267753002048	putative CoA binding site [chemical binding]; other site
1267753002049	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
1267753002050	putative trimer interface [polypeptide binding]; other site
1267753002051	putative CoA binding site [chemical binding]; other site
1267753002052	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1267753002053	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
1267753002054	gating phenylalanine in ion channel; other site
1267753002055	tellurite resistance protein TehB; Provisional; Region: PRK11207
1267753002056	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753002057	S-adenosylmethionine binding site [chemical binding]; other site
1267753002058	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
1267753002059	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
1267753002060	benzoate transporter; Region: benE; TIGR00843
1267753002061	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1267753002062	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753002063	non-specific DNA binding site [nucleotide binding]; other site
1267753002064	salt bridge; other site
1267753002065	sequence-specific DNA binding site [nucleotide binding]; other site
1267753002066	Cupin domain; Region: Cupin_2; pfam07883
1267753002067	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1267753002068	Peptidase family U32; Region: Peptidase_U32; pfam01136
1267753002069	Collagenase; Region: DUF3656; pfam12392
1267753002070	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
1267753002071	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
1267753002072	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
1267753002073	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1267753002074	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753002075	DNA-binding site [nucleotide binding]; DNA binding site
1267753002076	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753002077	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753002078	homodimer interface [polypeptide binding]; other site
1267753002079	catalytic residue [active]
1267753002080	1-pyrroline dehydrogenase; Region: ABALDH; TIGR03374
1267753002081	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
1267753002082	tetrameric interface [polypeptide binding]; other site
1267753002083	NAD binding site [chemical binding]; other site
1267753002084	catalytic residues [active]
1267753002085	substrate binding site [chemical binding]; other site
1267753002086	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
1267753002087	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
1267753002088	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
1267753002089	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
1267753002090	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1267753002091	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1267753002092	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1267753002093	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1267753002094	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1267753002095	NAD(P) binding site [chemical binding]; other site
1267753002096	substrate binding site [chemical binding]; other site
1267753002097	dimer interface [polypeptide binding]; other site
1267753002098	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
1267753002099	DNA-binding site [nucleotide binding]; DNA binding site
1267753002100	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1267753002101	FCD domain; Region: FCD; pfam07729
1267753002102	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1267753002103	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1267753002104	N-terminal plug; other site
1267753002105	ligand-binding site [chemical binding]; other site
1267753002106	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1267753002107	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1267753002108	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1267753002109	L-asparagine permease; Provisional; Region: PRK15049
1267753002110	N-acetyltransferase; Region: Acetyltransf_2; cl00949
1267753002111	hypothetical protein; Provisional; Region: PRK10281
1267753002112	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
1267753002113	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
1267753002114	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
1267753002115	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
1267753002116	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
1267753002117	[4Fe-4S] binding site [ion binding]; other site
1267753002118	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753002119	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753002120	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753002121	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
1267753002122	molybdopterin cofactor binding site; other site
1267753002123	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
1267753002124	TetR family transcriptional regulator; Provisional; Region: PRK14996
1267753002125	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753002126	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
1267753002127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002128	putative substrate translocation pore; other site
1267753002129	Uncharacterized conserved protein [Function unknown]; Region: COG3791
1267753002130	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1267753002131	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1267753002132	trimer interface [polypeptide binding]; other site
1267753002133	eyelet of channel; other site
1267753002134	aromatic amino acid exporter; Provisional; Region: PRK11689
1267753002135	potential frameshift: common BLAST hit: gi|379700741|ref|YP_005242469.1| formate dehydrogenase-N subunit alpha
1267753002136	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1267753002137	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1267753002138	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
1267753002139	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1267753002140	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
1267753002141	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
1267753002142	NAD binding site [chemical binding]; other site
1267753002143	substrate binding site [chemical binding]; other site
1267753002144	catalytic Zn binding site [ion binding]; other site
1267753002145	tetramer interface [polypeptide binding]; other site
1267753002146	structural Zn binding site [ion binding]; other site
1267753002147	malate dehydrogenase; Provisional; Region: PRK13529
1267753002148	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1267753002149	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
1267753002150	NAD(P) binding site [chemical binding]; other site
1267753002151	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
1267753002152	biofilm-dependent modulation protein; Provisional; Region: PRK11436
1267753002153	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
1267753002154	potential frameshift: common BLAST hit: gi|194738186|ref|YP_002114587.1| hemolysin E
1267753002155	acid-resistance protein; Provisional; Region: hdeB; PRK11566
1267753002156	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
1267753002157	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
1267753002158	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
1267753002159	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
1267753002160	catalytic site [active]
1267753002161	active site
1267753002162	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1267753002163	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
1267753002164	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
1267753002165	active site
1267753002166	catalytic site [active]
1267753002167	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
1267753002168	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1267753002169	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1267753002170	active site
1267753002171	catalytic site [active]
1267753002172	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1267753002173	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753002174	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753002175	homodimer interface [polypeptide binding]; other site
1267753002176	catalytic residue [active]
1267753002177	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
1267753002178	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1267753002179	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753002180	DNA binding site [nucleotide binding]
1267753002181	domain linker motif; other site
1267753002182	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1267753002183	dimerization interface (closed form) [polypeptide binding]; other site
1267753002184	ligand binding site [chemical binding]; other site
1267753002185	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1267753002186	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1267753002187	phosphate binding site [ion binding]; other site
1267753002188	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753002189	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753002190	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1267753002191	putative effector binding pocket; other site
1267753002192	putative dimerization interface [polypeptide binding]; other site
1267753002193	Domain of unknown function DUF29; Region: DUF29; pfam01724
1267753002194	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1267753002195	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
1267753002196	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1267753002197	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
1267753002198	homotrimer interaction site [polypeptide binding]; other site
1267753002199	putative active site [active]
1267753002200	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
1267753002201	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1267753002202	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1267753002203	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1267753002204	putative DNA binding site [nucleotide binding]; other site
1267753002205	putative Zn2+ binding site [ion binding]; other site
1267753002206	hypothetical protein; Provisional; Region: PRK06184
1267753002207	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1267753002208	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002209	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1267753002210	putative substrate translocation pore; other site
1267753002211	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
1267753002212	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1267753002213	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002214	D-galactonate transporter; Region: 2A0114; TIGR00893
1267753002215	putative substrate translocation pore; other site
1267753002216	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1267753002217	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1267753002218	putative NAD(P) binding site [chemical binding]; other site
1267753002219	catalytic Zn binding site [ion binding]; other site
1267753002220	structural Zn binding site [ion binding]; other site
1267753002221	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1267753002222	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753002223	DNA-binding site [nucleotide binding]; DNA binding site
1267753002224	FCD domain; Region: FCD; pfam07729
1267753002225	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1267753002226	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
1267753002227	active site
1267753002228	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
1267753002229	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1267753002230	hydrogenase 1 large subunit; Provisional; Region: PRK10170
1267753002231	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1267753002232	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
1267753002233	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1267753002234	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1267753002235	putative substrate-binding site; other site
1267753002236	nickel binding site [ion binding]; other site
1267753002237	HupF/HypC family; Region: HupF_HypC; cl00394
1267753002238	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
1267753002239	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1267753002240	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
1267753002241	Rubredoxin [Energy production and conversion]; Region: COG1773
1267753002242	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1267753002243	iron binding site [ion binding]; other site
1267753002244	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
1267753002245	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1267753002246	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1267753002247	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1267753002248	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1267753002249	trimer interface [polypeptide binding]; other site
1267753002250	eyelet of channel; other site
1267753002251	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
1267753002252	Predicted membrane protein [Function unknown]; Region: COG3781
1267753002253	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
1267753002254	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1267753002255	glutaminase; Provisional; Region: PRK00971
1267753002256	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
1267753002257	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1267753002258	NAD(P) binding site [chemical binding]; other site
1267753002259	catalytic residues [active]
1267753002260	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753002261	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753002262	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
1267753002263	putative dimerization interface [polypeptide binding]; other site
1267753002264	putative arabinose transporter; Provisional; Region: PRK03545
1267753002265	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002266	putative substrate translocation pore; other site
1267753002267	inner membrane protein; Provisional; Region: PRK10995
1267753002268	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
1267753002269	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1267753002270	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
1267753002271	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753002272	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753002273	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
1267753002274	EamA-like transporter family; Region: EamA; pfam00892
1267753002275	putative transporter; Provisional; Region: PRK10054
1267753002276	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002277	putative substrate translocation pore; other site
1267753002278	hypothetical protein; Provisional; Region: PRK10053
1267753002279	hypothetical protein; Validated; Region: PRK03657
1267753002280	General stress protein [General function prediction only]; Region: GsiB; COG3729
1267753002281	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
1267753002282	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1267753002283	active site
1267753002284	Zn binding site [ion binding]; other site
1267753002285	malonic semialdehyde reductase; Provisional; Region: PRK10538
1267753002286	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
1267753002287	putative NAD(P) binding site [chemical binding]; other site
1267753002288	homodimer interface [polypeptide binding]; other site
1267753002289	homotetramer interface [polypeptide binding]; other site
1267753002290	active site
1267753002291	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1267753002292	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753002293	DNA-binding site [nucleotide binding]; DNA binding site
1267753002294	FCD domain; Region: FCD; pfam07729
1267753002295	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
1267753002296	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
1267753002297	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1267753002298	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1267753002299	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002300	metabolite-proton symporter; Region: 2A0106; TIGR00883
1267753002301	putative substrate translocation pore; other site
1267753002302	putative oxidoreductase; Provisional; Region: PRK10083
1267753002303	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
1267753002304	putative NAD(P) binding site [chemical binding]; other site
1267753002305	catalytic Zn binding site [ion binding]; other site
1267753002306	structural Zn binding site [ion binding]; other site
1267753002307	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
1267753002308	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
1267753002309	putative active site pocket [active]
1267753002310	putative metal binding site [ion binding]; other site
1267753002311	hypothetical protein; Provisional; Region: PRK02237
1267753002312	hypothetical protein; Provisional; Region: PRK13659
1267753002313	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
1267753002314	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753002315	Coenzyme A binding pocket [chemical binding]; other site
1267753002316	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1267753002317	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
1267753002318	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
1267753002319	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1267753002320	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1267753002321	putative [Fe4-S4] binding site [ion binding]; other site
1267753002322	putative molybdopterin cofactor binding site [chemical binding]; other site
1267753002323	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1267753002324	putative molybdopterin cofactor binding site; other site
1267753002325	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1267753002326	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1267753002327	putative [Fe4-S4] binding site [ion binding]; other site
1267753002328	putative molybdopterin cofactor binding site [chemical binding]; other site
1267753002329	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1267753002330	putative molybdopterin cofactor binding site; other site
1267753002331	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1267753002332	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753002333	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1267753002334	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
1267753002335	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753002336	dimer interface [polypeptide binding]; other site
1267753002337	conserved gate region; other site
1267753002338	putative PBP binding loops; other site
1267753002339	ABC-ATPase subunit interface; other site
1267753002340	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1267753002341	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753002342	dimer interface [polypeptide binding]; other site
1267753002343	conserved gate region; other site
1267753002344	ABC-ATPase subunit interface; other site
1267753002345	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1267753002346	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1267753002347	Walker A/P-loop; other site
1267753002348	ATP binding site [chemical binding]; other site
1267753002349	Q-loop/lid; other site
1267753002350	ABC transporter signature motif; other site
1267753002351	Walker B; other site
1267753002352	D-loop; other site
1267753002353	H-loop/switch region; other site
1267753002354	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
1267753002355	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1267753002356	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1267753002357	Cl- selectivity filter; other site
1267753002358	Cl- binding residues [ion binding]; other site
1267753002359	pore gating glutamate residue; other site
1267753002360	dimer interface [polypeptide binding]; other site
1267753002361	putative dithiobiotin synthetase; Provisional; Region: PRK12374
1267753002362	AAA domain; Region: AAA_26; pfam13500
1267753002363	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1267753002364	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1267753002365	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1267753002366	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1267753002367	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753002368	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
1267753002369	dimerization interface [polypeptide binding]; other site
1267753002370	substrate binding pocket [chemical binding]; other site
1267753002371	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1267753002372	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002373	putative substrate translocation pore; other site
1267753002374	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1267753002375	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
1267753002376	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
1267753002377	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
1267753002378	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1267753002379	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
1267753002380	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
1267753002381	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
1267753002382	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
1267753002383	ligand binding site [chemical binding]; other site
1267753002384	homodimer interface [polypeptide binding]; other site
1267753002385	NAD(P) binding site [chemical binding]; other site
1267753002386	trimer interface B [polypeptide binding]; other site
1267753002387	trimer interface A [polypeptide binding]; other site
1267753002388	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
1267753002389	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753002390	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753002391	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753002392	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
1267753002393	Spore germination protein; Region: Spore_permease; cl17796
1267753002394	GlpM protein; Region: GlpM; pfam06942
1267753002395	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
1267753002396	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753002397	active site
1267753002398	phosphorylation site [posttranslational modification]
1267753002399	intermolecular recognition site; other site
1267753002400	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753002401	DNA binding site [nucleotide binding]
1267753002402	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1267753002403	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1267753002404	trimer interface [polypeptide binding]; other site
1267753002405	eyelet of channel; other site
1267753002406	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1267753002407	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1267753002408	active site
1267753002409	sensor protein RstB; Provisional; Region: PRK10604
1267753002410	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753002411	dimerization interface [polypeptide binding]; other site
1267753002412	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753002413	dimer interface [polypeptide binding]; other site
1267753002414	phosphorylation site [posttranslational modification]
1267753002415	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753002416	ATP binding site [chemical binding]; other site
1267753002417	Mg2+ binding site [ion binding]; other site
1267753002418	G-X-G motif; other site
1267753002419	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
1267753002420	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1267753002421	Class II fumarases; Region: Fumarase_classII; cd01362
1267753002422	active site
1267753002423	tetramer interface [polypeptide binding]; other site
1267753002424	fumarate hydratase; Provisional; Region: PRK15389
1267753002425	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1267753002426	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1267753002427	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
1267753002428	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1267753002429	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1267753002430	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
1267753002431	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
1267753002432	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
1267753002433	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753002434	DNA binding site [nucleotide binding]
1267753002435	domain linker motif; other site
1267753002436	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
1267753002437	putative dimerization interface [polypeptide binding]; other site
1267753002438	putative ligand binding site [chemical binding]; other site
1267753002439	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
1267753002440	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
1267753002441	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1267753002442	active site turn [active]
1267753002443	phosphorylation site [posttranslational modification]
1267753002444	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1267753002445	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753002446	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753002447	homodimer interface [polypeptide binding]; other site
1267753002448	catalytic residue [active]
1267753002449	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
1267753002450	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
1267753002451	active site
1267753002452	purine riboside binding site [chemical binding]; other site
1267753002453	putative oxidoreductase; Provisional; Region: PRK11579
1267753002454	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1267753002455	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1267753002456	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
1267753002457	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
1267753002458	electron transport complex protein RsxA; Provisional; Region: PRK05151
1267753002459	electron transport complex protein RnfB; Provisional; Region: PRK05113
1267753002460	Putative Fe-S cluster; Region: FeS; cl17515
1267753002461	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753002462	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
1267753002463	SLBB domain; Region: SLBB; pfam10531
1267753002464	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1267753002465	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
1267753002466	electron transport complex protein RnfG; Validated; Region: PRK01908
1267753002467	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1267753002468	endonuclease III; Provisional; Region: PRK10702
1267753002469	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1267753002470	minor groove reading motif; other site
1267753002471	helix-hairpin-helix signature motif; other site
1267753002472	substrate binding pocket [chemical binding]; other site
1267753002473	active site
1267753002474	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1267753002475	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1267753002476	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002477	putative substrate translocation pore; other site
1267753002478	POT family; Region: PTR2; pfam00854
1267753002479	glutathionine S-transferase; Provisional; Region: PRK10542
1267753002480	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
1267753002481	C-terminal domain interface [polypeptide binding]; other site
1267753002482	GSH binding site (G-site) [chemical binding]; other site
1267753002483	dimer interface [polypeptide binding]; other site
1267753002484	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
1267753002485	dimer interface [polypeptide binding]; other site
1267753002486	N-terminal domain interface [polypeptide binding]; other site
1267753002487	substrate binding pocket (H-site) [chemical binding]; other site
1267753002488	pyridoxamine kinase; Validated; Region: PRK05756
1267753002489	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1267753002490	dimer interface [polypeptide binding]; other site
1267753002491	pyridoxal binding site [chemical binding]; other site
1267753002492	ATP binding site [chemical binding]; other site
1267753002493	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1267753002494	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1267753002495	active site
1267753002496	HIGH motif; other site
1267753002497	dimer interface [polypeptide binding]; other site
1267753002498	KMSKS motif; other site
1267753002499	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1267753002500	RNA binding surface [nucleotide binding]; other site
1267753002501	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
1267753002502	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1267753002503	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1267753002504	lysozyme inhibitor; Provisional; Region: PRK11372
1267753002505	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
1267753002506	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1267753002507	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
1267753002508	transcriptional regulator SlyA; Provisional; Region: PRK03573
1267753002509	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
1267753002510	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
1267753002511	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1267753002512	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753002513	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753002514	Fusaric acid resistance protein family; Region: FUSC; pfam04632
1267753002515	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1267753002516	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
1267753002517	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
1267753002518	E-class dimer interface [polypeptide binding]; other site
1267753002519	P-class dimer interface [polypeptide binding]; other site
1267753002520	active site
1267753002521	Cu2+ binding site [ion binding]; other site
1267753002522	Zn2+ binding site [ion binding]; other site
1267753002523	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1267753002524	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1267753002525	active site
1267753002526	catalytic tetrad [active]
1267753002527	Predicted Fe-S protein [General function prediction only]; Region: COG3313
1267753002528	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1267753002529	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753002530	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1267753002531	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
1267753002532	FMN binding site [chemical binding]; other site
1267753002533	active site
1267753002534	substrate binding site [chemical binding]; other site
1267753002535	catalytic residue [active]
1267753002536	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1267753002537	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1267753002538	dimer interface [polypeptide binding]; other site
1267753002539	active site
1267753002540	metal binding site [ion binding]; metal-binding site
1267753002541	glutathione binding site [chemical binding]; other site
1267753002542	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1267753002543	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
1267753002544	dimer interface [polypeptide binding]; other site
1267753002545	catalytic site [active]
1267753002546	putative active site [active]
1267753002547	putative substrate binding site [chemical binding]; other site
1267753002548	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
1267753002549	putative GSH binding site [chemical binding]; other site
1267753002550	catalytic residues [active]
1267753002551	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1267753002552	NlpC/P60 family; Region: NLPC_P60; cl17555
1267753002553	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1267753002554	NlpC/P60 family; Region: NLPC_P60; cl17555
1267753002555	superoxide dismutase; Provisional; Region: PRK10543
1267753002556	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1267753002557	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1267753002558	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
1267753002559	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753002560	DNA binding site [nucleotide binding]
1267753002561	domain linker motif; other site
1267753002562	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1267753002563	dimerization interface [polypeptide binding]; other site
1267753002564	ligand binding site [chemical binding]; other site
1267753002565	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1267753002566	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753002567	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1267753002568	dimerization interface [polypeptide binding]; other site
1267753002569	putative transporter; Provisional; Region: PRK11043
1267753002570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002571	putative substrate translocation pore; other site
1267753002572	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
1267753002573	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753002574	S-adenosylmethionine binding site [chemical binding]; other site
1267753002575	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
1267753002576	Lumazine binding domain; Region: Lum_binding; pfam00677
1267753002577	Lumazine binding domain; Region: Lum_binding; pfam00677
1267753002578	multidrug efflux protein; Reviewed; Region: PRK01766
1267753002579	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1267753002580	cation binding site [ion binding]; other site
1267753002581	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
1267753002582	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1267753002583	type III secretion system protein SsaT; Provisional; Region: PRK15349
1267753002584	type III secretion system protein SsaS; Provisional; Region: PRK15350
1267753002585	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
1267753002586	type III secretion system protein SsaQ; Validated; Region: PRK08035
1267753002587	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1267753002588	type III secretion system protein SsaP; Provisional; Region: PRK15351
1267753002589	type III secretion system protein SsaO; Provisional; Region: PRK15352
1267753002590	type III secretion system ATPase SsaN; Validated; Region: PRK07594
1267753002591	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1267753002592	Walker A motif; other site
1267753002593	ATP binding site [chemical binding]; other site
1267753002594	Walker B motif; other site
1267753002595	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
1267753002596	FHIPEP family; Region: FHIPEP; pfam00771
1267753002597	type III secretion system protein SsaM; Provisional; Region: PRK15353
1267753002598	type III secretion system protein SsaL; Provisional; Region: PRK15345
1267753002599	HrpJ-like domain; Region: HrpJ; pfam07201
1267753002600	TyeA; Region: TyeA; cl07611
1267753002601	type III secretion system protein SsaK; Provisional; Region: PRK15354
1267753002602	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
1267753002603	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
1267753002604	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
1267753002605	type III secretion system protein SsaI; Provisional; Region: PRK15355
1267753002606	type III secretion system protein SsaH; Provisional; Region: PRK15356
1267753002607	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
1267753002608	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
1267753002609	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
1267753002610	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
1267753002611	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1267753002612	TPR motif; other site
1267753002613	binding surface
1267753002614	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
1267753002615	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
1267753002616	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
1267753002617	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
1267753002618	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
1267753002619	type III secretion system chaperone SseA; Provisional; Region: PRK15365
1267753002620	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
1267753002621	type III secretion system protein SsaD; Provisional; Region: PRK15367
1267753002622	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
1267753002623	outer membrane secretin SsaC; Provisional; Region: PRK15346
1267753002624	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1267753002625	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1267753002626	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
1267753002627	two component system sensor kinase SsrA; Provisional; Region: PRK15347
1267753002628	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753002629	dimerization interface [polypeptide binding]; other site
1267753002630	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753002631	dimer interface [polypeptide binding]; other site
1267753002632	phosphorylation site [posttranslational modification]
1267753002633	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753002634	ATP binding site [chemical binding]; other site
1267753002635	Mg2+ binding site [ion binding]; other site
1267753002636	G-X-G motif; other site
1267753002637	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753002638	active site
1267753002639	phosphorylation site [posttranslational modification]
1267753002640	intermolecular recognition site; other site
1267753002641	dimerization interface [polypeptide binding]; other site
1267753002642	two component system sensor kinase SsrB; Provisional; Region: PRK15369
1267753002643	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753002644	active site
1267753002645	phosphorylation site [posttranslational modification]
1267753002646	intermolecular recognition site; other site
1267753002647	dimerization interface [polypeptide binding]; other site
1267753002648	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753002649	DNA binding residues [nucleotide binding]
1267753002650	dimerization interface [polypeptide binding]; other site
1267753002651	transcriptional regulator MirA; Provisional; Region: PRK15043
1267753002652	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1267753002653	DNA binding residues [nucleotide binding]
1267753002654	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1267753002655	Uncharacterized conserved protein [Function unknown]; Region: COG3272
1267753002656	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
1267753002657	hypothetical protein; Provisional; Region: PRK10292
1267753002658	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
1267753002659	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753002660	active site
1267753002661	phosphorylation site [posttranslational modification]
1267753002662	intermolecular recognition site; other site
1267753002663	dimerization interface [polypeptide binding]; other site
1267753002664	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753002665	DNA binding residues [nucleotide binding]
1267753002666	dimerization interface [polypeptide binding]; other site
1267753002667	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1267753002668	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753002669	dimer interface [polypeptide binding]; other site
1267753002670	phosphorylation site [posttranslational modification]
1267753002671	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753002672	ATP binding site [chemical binding]; other site
1267753002673	Mg2+ binding site [ion binding]; other site
1267753002674	G-X-G motif; other site
1267753002675	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1267753002676	tetrathionate reductase subunit B; Provisional; Region: PRK14993
1267753002677	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753002678	tetrathionate reductase subunit C; Provisional; Region: PRK14992
1267753002679	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1267753002680	tetrathionate reductase subunit A; Provisional; Region: PRK14991
1267753002681	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
1267753002682	putative [Fe4-S4] binding site [ion binding]; other site
1267753002683	putative molybdopterin cofactor binding site [chemical binding]; other site
1267753002684	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
1267753002685	putative molybdopterin cofactor binding site; other site
1267753002686	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753002687	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1267753002688	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753002689	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1267753002690	substrate binding site [chemical binding]; other site
1267753002691	dimer interface [polypeptide binding]; other site
1267753002692	ATP binding site [chemical binding]; other site
1267753002693	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1267753002694	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
1267753002695	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1267753002696	pyruvate kinase; Provisional; Region: PRK09206
1267753002697	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
1267753002698	domain interfaces; other site
1267753002699	active site
1267753002700	murein lipoprotein; Provisional; Region: PRK15396
1267753002701	murein lipoprotein; Provisional; Region: PRK15396
1267753002702	murein lipoprotein; Provisional; Region: PRK15396
1267753002703	L,D-transpeptidase; Provisional; Region: PRK10190
1267753002704	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1267753002705	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1267753002706	cysteine desufuration protein SufE; Provisional; Region: PRK09296
1267753002707	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1267753002708	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1267753002709	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1267753002710	catalytic residue [active]
1267753002711	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
1267753002712	FeS assembly protein SufD; Region: sufD; TIGR01981
1267753002713	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
1267753002714	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1267753002715	Walker A/P-loop; other site
1267753002716	ATP binding site [chemical binding]; other site
1267753002717	Q-loop/lid; other site
1267753002718	ABC transporter signature motif; other site
1267753002719	Walker B; other site
1267753002720	D-loop; other site
1267753002721	H-loop/switch region; other site
1267753002722	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1267753002723	putative ABC transporter; Region: ycf24; CHL00085
1267753002724	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
1267753002725	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1267753002726	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1267753002727	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1267753002728	CoenzymeA binding site [chemical binding]; other site
1267753002729	subunit interaction site [polypeptide binding]; other site
1267753002730	PHB binding site; other site
1267753002731	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1267753002732	FAD binding domain; Region: FAD_binding_4; pfam01565
1267753002733	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1267753002734	putative inner membrane protein; Provisional; Region: PRK10983
1267753002735	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1267753002736	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
1267753002737	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002738	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1267753002739	putative substrate translocation pore; other site
1267753002740	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753002741	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1267753002742	putative substrate translocation pore; other site
1267753002743	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
1267753002744	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1267753002745	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1267753002746	shikimate binding site; other site
1267753002747	NAD(P) binding site [chemical binding]; other site
1267753002748	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
1267753002749	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
1267753002750	active site
1267753002751	catalytic residue [active]
1267753002752	dimer interface [polypeptide binding]; other site
1267753002753	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
1267753002754	Coenzyme A transferase; Region: CoA_trans; smart00882
1267753002755	Coenzyme A transferase; Region: CoA_trans; cl17247
1267753002756	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
1267753002757	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1267753002758	active site
1267753002759	Cupin domain; Region: Cupin_2; pfam07883
1267753002760	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1267753002761	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753002762	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1267753002763	Ligand binding site [chemical binding]; other site
1267753002764	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1267753002765	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
1267753002766	Electron transfer flavoprotein domain; Region: ETF; smart00893
1267753002767	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1267753002768	oxidoreductase; Provisional; Region: PRK10015
1267753002769	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1267753002770	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
1267753002771	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
1267753002772	acyl-activating enzyme (AAE) consensus motif; other site
1267753002773	putative AMP binding site [chemical binding]; other site
1267753002774	putative active site [active]
1267753002775	putative CoA binding site [chemical binding]; other site
1267753002776	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1267753002777	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1267753002778	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1267753002779	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1267753002780	PEP synthetase regulatory protein; Provisional; Region: PRK05339
1267753002781	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
1267753002782	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1267753002783	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
1267753002784	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1267753002785	hypothetical protein; Validated; Region: PRK00029
1267753002786	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
1267753002787	NlpC/P60 family; Region: NLPC_P60; pfam00877
1267753002788	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
1267753002789	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1267753002790	Walker A/P-loop; other site
1267753002791	ATP binding site [chemical binding]; other site
1267753002792	Q-loop/lid; other site
1267753002793	ABC transporter signature motif; other site
1267753002794	Walker B; other site
1267753002795	D-loop; other site
1267753002796	H-loop/switch region; other site
1267753002797	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1267753002798	catalytic residues [active]
1267753002799	dimer interface [polypeptide binding]; other site
1267753002800	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1267753002801	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1267753002802	ABC-ATPase subunit  interface; other site
1267753002803	dimer interface [polypeptide binding]; other site
1267753002804	putative PBP binding regions; other site
1267753002805	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1267753002806	IHF dimer interface [polypeptide binding]; other site
1267753002807	IHF - DNA interface [nucleotide binding]; other site
1267753002808	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1267753002809	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1267753002810	putative tRNA-binding site [nucleotide binding]; other site
1267753002811	B3/4 domain; Region: B3_4; pfam03483
1267753002812	tRNA synthetase B5 domain; Region: B5; smart00874
1267753002813	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1267753002814	dimer interface [polypeptide binding]; other site
1267753002815	motif 1; other site
1267753002816	motif 3; other site
1267753002817	motif 2; other site
1267753002818	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1267753002819	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1267753002820	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1267753002821	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1267753002822	dimer interface [polypeptide binding]; other site
1267753002823	motif 1; other site
1267753002824	active site
1267753002825	motif 2; other site
1267753002826	motif 3; other site
1267753002827	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1267753002828	23S rRNA binding site [nucleotide binding]; other site
1267753002829	L21 binding site [polypeptide binding]; other site
1267753002830	L13 binding site [polypeptide binding]; other site
1267753002831	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1267753002832	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1267753002833	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1267753002834	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1267753002835	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1267753002836	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1267753002837	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1267753002838	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1267753002839	active site
1267753002840	dimer interface [polypeptide binding]; other site
1267753002841	motif 1; other site
1267753002842	motif 2; other site
1267753002843	motif 3; other site
1267753002844	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1267753002845	anticodon binding site; other site
1267753002846	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
1267753002847	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1267753002848	active site
1267753002849	substrate binding site [chemical binding]; other site
1267753002850	Mg2+ binding site [ion binding]; other site
1267753002851	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
1267753002852	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
1267753002853	6-phosphofructokinase 2; Provisional; Region: PRK10294
1267753002854	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1267753002855	putative substrate binding site [chemical binding]; other site
1267753002856	putative ATP binding site [chemical binding]; other site
1267753002857	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
1267753002858	Phosphotransferase enzyme family; Region: APH; pfam01636
1267753002859	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1267753002860	active site
1267753002861	ATP binding site [chemical binding]; other site
1267753002862	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1267753002863	YniB-like protein; Region: YniB; pfam14002
1267753002864	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
1267753002865	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1267753002866	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753002867	motif II; other site
1267753002868	inner membrane protein; Provisional; Region: PRK11648
1267753002869	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1267753002870	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1267753002871	cell division modulator; Provisional; Region: PRK10113
1267753002872	hydroperoxidase II; Provisional; Region: katE; PRK11249
1267753002873	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
1267753002874	tetramer interface [polypeptide binding]; other site
1267753002875	heme binding pocket [chemical binding]; other site
1267753002876	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
1267753002877	domain interactions; other site
1267753002878	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
1267753002879	putative active site [active]
1267753002880	YdjC motif; other site
1267753002881	Mg binding site [ion binding]; other site
1267753002882	putative homodimer interface [polypeptide binding]; other site
1267753002883	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1267753002884	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1267753002885	NAD binding site [chemical binding]; other site
1267753002886	sugar binding site [chemical binding]; other site
1267753002887	divalent metal binding site [ion binding]; other site
1267753002888	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1267753002889	dimer interface [polypeptide binding]; other site
1267753002890	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
1267753002891	Cupin domain; Region: Cupin_2; pfam07883
1267753002892	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753002893	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1267753002894	methionine cluster; other site
1267753002895	active site
1267753002896	phosphorylation site [posttranslational modification]
1267753002897	metal binding site [ion binding]; metal-binding site
1267753002898	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
1267753002899	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1267753002900	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1267753002901	active site
1267753002902	P-loop; other site
1267753002903	phosphorylation site [posttranslational modification]
1267753002904	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
1267753002905	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1267753002906	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1267753002907	homodimer interface [polypeptide binding]; other site
1267753002908	NAD binding pocket [chemical binding]; other site
1267753002909	ATP binding pocket [chemical binding]; other site
1267753002910	Mg binding site [ion binding]; other site
1267753002911	active-site loop [active]
1267753002912	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1267753002913	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1267753002914	GIY-YIG motif/motif A; other site
1267753002915	active site
1267753002916	catalytic site [active]
1267753002917	putative DNA binding site [nucleotide binding]; other site
1267753002918	metal binding site [ion binding]; metal-binding site
1267753002919	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1267753002920	dimer interface [polypeptide binding]; other site
1267753002921	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
1267753002922	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
1267753002923	putative active site [active]
1267753002924	Zn binding site [ion binding]; other site
1267753002925	succinylarginine dihydrolase; Provisional; Region: PRK13281
1267753002926	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
1267753002927	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
1267753002928	NAD(P) binding site [chemical binding]; other site
1267753002929	catalytic residues [active]
1267753002930	arginine succinyltransferase; Provisional; Region: PRK10456
1267753002931	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
1267753002932	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
1267753002933	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1267753002934	inhibitor-cofactor binding pocket; inhibition site
1267753002935	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753002936	catalytic residue [active]
1267753002937	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
1267753002938	putative catalytic site [active]
1267753002939	putative phosphate binding site [ion binding]; other site
1267753002940	active site
1267753002941	metal binding site A [ion binding]; metal-binding site
1267753002942	DNA binding site [nucleotide binding]
1267753002943	putative AP binding site [nucleotide binding]; other site
1267753002944	putative metal binding site B [ion binding]; other site
1267753002945	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1267753002946	active site
1267753002947	8-oxo-dGMP binding site [chemical binding]; other site
1267753002948	nudix motif; other site
1267753002949	metal binding site [ion binding]; metal-binding site
1267753002950	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
1267753002951	glutamate dehydrogenase; Provisional; Region: PRK09414
1267753002952	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1267753002953	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1267753002954	NAD(P) binding site [chemical binding]; other site
1267753002955	DNA topoisomerase III; Provisional; Region: PRK07726
1267753002956	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1267753002957	active site
1267753002958	putative interdomain interaction site [polypeptide binding]; other site
1267753002959	putative metal-binding site [ion binding]; other site
1267753002960	putative nucleotide binding site [chemical binding]; other site
1267753002961	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1267753002962	domain I; other site
1267753002963	DNA binding groove [nucleotide binding]
1267753002964	phosphate binding site [ion binding]; other site
1267753002965	domain II; other site
1267753002966	domain III; other site
1267753002967	nucleotide binding site [chemical binding]; other site
1267753002968	catalytic site [active]
1267753002969	domain IV; other site
1267753002970	selenophosphate synthetase; Provisional; Region: PRK00943
1267753002971	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1267753002972	dimerization interface [polypeptide binding]; other site
1267753002973	putative ATP binding site [chemical binding]; other site
1267753002974	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1267753002975	putative FMN binding site [chemical binding]; other site
1267753002976	protease 4; Provisional; Region: PRK10949
1267753002977	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1267753002978	tandem repeat interface [polypeptide binding]; other site
1267753002979	oligomer interface [polypeptide binding]; other site
1267753002980	active site residues [active]
1267753002981	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
1267753002982	tandem repeat interface [polypeptide binding]; other site
1267753002983	oligomer interface [polypeptide binding]; other site
1267753002984	active site residues [active]
1267753002985	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1267753002986	active site
1267753002987	homodimer interface [polypeptide binding]; other site
1267753002988	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
1267753002989	Isochorismatase family; Region: Isochorismatase; pfam00857
1267753002990	catalytic triad [active]
1267753002991	metal binding site [ion binding]; metal-binding site
1267753002992	conserved cis-peptide bond; other site
1267753002993	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
1267753002994	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1267753002995	SelR domain; Region: SelR; pfam01641
1267753002996	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
1267753002997	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1267753002998	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1267753002999	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
1267753003000	active site
1267753003001	phosphate binding residues; other site
1267753003002	catalytic residues [active]
1267753003003	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1267753003004	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1267753003005	active site
1267753003006	catalytic tetrad [active]
1267753003007	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1267753003008	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753003009	FeS/SAM binding site; other site
1267753003010	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1267753003011	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
1267753003012	PrkA family serine protein kinase; Provisional; Region: PRK15455
1267753003013	AAA ATPase domain; Region: AAA_16; pfam13191
1267753003014	Walker A motif; other site
1267753003015	ATP binding site [chemical binding]; other site
1267753003016	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
1267753003017	hypothetical protein; Provisional; Region: PRK05325
1267753003018	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1267753003019	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753003020	metal binding site [ion binding]; metal-binding site
1267753003021	active site
1267753003022	I-site; other site
1267753003023	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
1267753003024	putative deacylase active site [active]
1267753003025	Predicted membrane protein [Function unknown]; Region: COG2707
1267753003026	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1267753003027	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753003028	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1267753003029	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753003030	Uncharacterized conserved protein [Function unknown]; Region: COG3189
1267753003031	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
1267753003032	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1267753003033	Domain of unknown function (DUF333); Region: DUF333; pfam03891
1267753003034	hypothetical protein; Provisional; Region: PRK10457
1267753003035	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
1267753003036	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
1267753003037	leucine export protein LeuE; Provisional; Region: PRK10958
1267753003038	chorismate mutase; Provisional; Region: PRK08055
1267753003039	Pleckstrin homology-like domain; Region: PH-like; cl17171
1267753003040	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
1267753003041	transcriptional regulator MirA; Provisional; Region: PRK15043
1267753003042	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
1267753003043	DNA binding residues [nucleotide binding]
1267753003044	dimer interface [polypeptide binding]; other site
1267753003045	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753003046	DNA binding residues [nucleotide binding]
1267753003047	aminoglycoside resistance protein; Provisional; Region: PRK13746
1267753003048	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1267753003049	active site
1267753003050	NTP binding site [chemical binding]; other site
1267753003051	metal binding triad [ion binding]; metal-binding site
1267753003052	antibiotic binding site [chemical binding]; other site
1267753003053	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
1267753003054	zinc/cadmium-binding protein; Provisional; Region: PRK10306
1267753003055	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
1267753003056	dimerization interface [polypeptide binding]; other site
1267753003057	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1267753003058	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1267753003059	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753003060	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1267753003061	Walker A/P-loop; other site
1267753003062	ATP binding site [chemical binding]; other site
1267753003063	Q-loop/lid; other site
1267753003064	ABC transporter signature motif; other site
1267753003065	Walker B; other site
1267753003066	D-loop; other site
1267753003067	H-loop/switch region; other site
1267753003068	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753003069	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1267753003070	Walker A/P-loop; other site
1267753003071	ATP binding site [chemical binding]; other site
1267753003072	Q-loop/lid; other site
1267753003073	ABC transporter signature motif; other site
1267753003074	Walker B; other site
1267753003075	D-loop; other site
1267753003076	H-loop/switch region; other site
1267753003077	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1267753003078	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753003079	dimer interface [polypeptide binding]; other site
1267753003080	conserved gate region; other site
1267753003081	putative PBP binding loops; other site
1267753003082	ABC-ATPase subunit interface; other site
1267753003083	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1267753003084	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753003085	dimer interface [polypeptide binding]; other site
1267753003086	conserved gate region; other site
1267753003087	ABC-ATPase subunit interface; other site
1267753003088	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1267753003089	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
1267753003090	TRL-like protein family; Region: TRL; pfam13146
1267753003091	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1267753003092	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
1267753003093	BNR repeat-like domain; Region: BNR_2; pfam13088
1267753003094	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1267753003095	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1267753003096	putative dimer interface [polypeptide binding]; other site
1267753003097	lysozyme inhibitor; Provisional; Region: PRK13791
1267753003098	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1267753003099	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1267753003100	DNA-binding site [nucleotide binding]; DNA binding site
1267753003101	RNA-binding motif; other site
1267753003102	Ricin-type beta-trefoil; Region: RICIN; smart00458
1267753003103	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1267753003104	putative sugar binding sites [chemical binding]; other site
1267753003105	Q-X-W motif; other site
1267753003106	DinI-like family; Region: DinI; pfam06183
1267753003107	putative transposase OrfB; Reviewed; Region: PHA02517
1267753003108	CdtB, the catalytic DNase I-like subunit of cytolethal distending toxin (CDT) protein; Region: CdtB; cd09081
1267753003109	putative catalytic site [active]
1267753003110	CdtC interface [polypeptide binding]; other site
1267753003111	heterotrimer interface [polypeptide binding]; other site
1267753003112	CdtA interface [polypeptide binding]; other site
1267753003113	putative metal binding site [ion binding]; other site
1267753003114	putative phosphate binding site [ion binding]; other site
1267753003115	Protein of unknown function (DUF1353); Region: DUF1353; pfam07087
1267753003116	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1267753003117	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1267753003118	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1267753003119	pertussis toxin-like subunit ArtA; Provisional; Region: PRK15272
1267753003120	subtilase cytotoxin subunit B; Provisional; Region: PRK15266
1267753003121	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
1267753003122	isocitrate dehydrogenase; Validated; Region: PRK07362
1267753003123	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1267753003124	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
1267753003125	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
1267753003126	probable active site [active]
1267753003127	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
1267753003128	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
1267753003129	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
1267753003130	nudix motif; other site
1267753003131	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1267753003132	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
1267753003133	putative lysogenization regulator; Reviewed; Region: PRK00218
1267753003134	adenylosuccinate lyase; Provisional; Region: PRK09285
1267753003135	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1267753003136	tetramer interface [polypeptide binding]; other site
1267753003137	active site
1267753003138	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
1267753003139	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753003140	active site
1267753003141	phosphorylation site [posttranslational modification]
1267753003142	intermolecular recognition site; other site
1267753003143	dimerization interface [polypeptide binding]; other site
1267753003144	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753003145	DNA binding site [nucleotide binding]
1267753003146	sensor protein PhoQ; Provisional; Region: PRK10815
1267753003147	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1267753003148	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1267753003149	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753003150	ATP binding site [chemical binding]; other site
1267753003151	Mg2+ binding site [ion binding]; other site
1267753003152	G-X-G motif; other site
1267753003153	Uncharacterized conserved protein [Function unknown]; Region: COG2850
1267753003154	Cupin domain; Region: Cupin_2; cl17218
1267753003155	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
1267753003156	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1267753003157	metal binding site [ion binding]; metal-binding site
1267753003158	dimer interface [polypeptide binding]; other site
1267753003159	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
1267753003160	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753003161	Walker A/P-loop; other site
1267753003162	ATP binding site [chemical binding]; other site
1267753003163	Q-loop/lid; other site
1267753003164	ABC transporter signature motif; other site
1267753003165	Walker B; other site
1267753003166	D-loop; other site
1267753003167	H-loop/switch region; other site
1267753003168	TOBE domain; Region: TOBE_2; pfam08402
1267753003169	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1267753003170	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753003171	dimer interface [polypeptide binding]; other site
1267753003172	conserved gate region; other site
1267753003173	putative PBP binding loops; other site
1267753003174	ABC-ATPase subunit interface; other site
1267753003175	secreted effector protein SifA; Reviewed; Region: sifA; PRK09498
1267753003176	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1267753003177	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753003178	dimer interface [polypeptide binding]; other site
1267753003179	conserved gate region; other site
1267753003180	putative PBP binding loops; other site
1267753003181	ABC-ATPase subunit interface; other site
1267753003182	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
1267753003183	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1267753003184	NAD-dependent deacetylase; Provisional; Region: PRK00481
1267753003185	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1267753003186	NAD+ binding site [chemical binding]; other site
1267753003187	substrate binding site [chemical binding]; other site
1267753003188	Zn binding site [ion binding]; other site
1267753003189	fructokinase; Reviewed; Region: PRK09557
1267753003190	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1267753003191	nucleotide binding site [chemical binding]; other site
1267753003192	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
1267753003193	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1267753003194	FtsX-like permease family; Region: FtsX; pfam02687
1267753003195	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
1267753003196	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1267753003197	Walker A/P-loop; other site
1267753003198	ATP binding site [chemical binding]; other site
1267753003199	Q-loop/lid; other site
1267753003200	ABC transporter signature motif; other site
1267753003201	Walker B; other site
1267753003202	D-loop; other site
1267753003203	H-loop/switch region; other site
1267753003204	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
1267753003205	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1267753003206	FtsX-like permease family; Region: FtsX; pfam02687
1267753003207	transcription-repair coupling factor; Provisional; Region: PRK10689
1267753003208	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1267753003209	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753003210	ATP binding site [chemical binding]; other site
1267753003211	putative Mg++ binding site [ion binding]; other site
1267753003212	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753003213	nucleotide binding region [chemical binding]; other site
1267753003214	ATP-binding site [chemical binding]; other site
1267753003215	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1267753003216	L,D-transpeptidase; Provisional; Region: PRK10190
1267753003217	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1267753003218	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1267753003219	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753003220	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1267753003221	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753003222	hypothetical protein; Provisional; Region: PRK11280
1267753003223	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1267753003224	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753003225	hypothetical protein; Provisional; Region: PRK04940
1267753003226	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1267753003227	beta-hexosaminidase; Provisional; Region: PRK05337
1267753003228	thiamine kinase; Region: ycfN_thiK; TIGR02721
1267753003229	thiamine kinase; Provisional; Region: thiK; PRK10271
1267753003230	substrate binding site [chemical binding]; other site
1267753003231	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
1267753003232	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1267753003233	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1267753003234	putative dimer interface [polypeptide binding]; other site
1267753003235	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1267753003236	nucleotide binding site/active site [active]
1267753003237	HIT family signature motif; other site
1267753003238	catalytic residue [active]
1267753003239	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
1267753003240	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1267753003241	N-terminal plug; other site
1267753003242	ligand-binding site [chemical binding]; other site
1267753003243	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
1267753003244	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1267753003245	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1267753003246	active site turn [active]
1267753003247	phosphorylation site [posttranslational modification]
1267753003248	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1267753003249	active site
1267753003250	DNA polymerase III subunit delta'; Validated; Region: PRK07993
1267753003251	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
1267753003252	thymidylate kinase; Validated; Region: tmk; PRK00698
1267753003253	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1267753003254	TMP-binding site; other site
1267753003255	ATP-binding site [chemical binding]; other site
1267753003256	conserved hypothetical protein, YceG family; Region: TIGR00247
1267753003257	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1267753003258	dimerization interface [polypeptide binding]; other site
1267753003259	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1267753003260	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1267753003261	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753003262	catalytic residue [active]
1267753003263	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1267753003264	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1267753003265	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753003266	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753003267	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
1267753003268	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753003269	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753003270	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753003271	Fimbrial protein; Region: Fimbrial; pfam00419
1267753003272	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1267753003273	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1267753003274	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
1267753003275	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1267753003276	dimer interface [polypeptide binding]; other site
1267753003277	active site
1267753003278	acyl carrier protein; Provisional; Region: acpP; PRK00982
1267753003279	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1267753003280	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1267753003281	NAD(P) binding site [chemical binding]; other site
1267753003282	homotetramer interface [polypeptide binding]; other site
1267753003283	homodimer interface [polypeptide binding]; other site
1267753003284	active site
1267753003285	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1267753003286	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1267753003287	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1267753003288	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1267753003289	dimer interface [polypeptide binding]; other site
1267753003290	active site
1267753003291	CoA binding pocket [chemical binding]; other site
1267753003292	putative phosphate acyltransferase; Provisional; Region: PRK05331
1267753003293	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1267753003294	hypothetical protein; Provisional; Region: PRK11193
1267753003295	Maf-like protein; Region: Maf; pfam02545
1267753003296	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1267753003297	active site
1267753003298	dimer interface [polypeptide binding]; other site
1267753003299	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1267753003300	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
1267753003301	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1267753003302	RNA binding surface [nucleotide binding]; other site
1267753003303	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1267753003304	active site
1267753003305	ribonuclease E; Reviewed; Region: rne; PRK10811
1267753003306	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1267753003307	homodimer interface [polypeptide binding]; other site
1267753003308	oligonucleotide binding site [chemical binding]; other site
1267753003309	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
1267753003310	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
1267753003311	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1267753003312	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
1267753003313	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1267753003314	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
1267753003315	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
1267753003316	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
1267753003317	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1267753003318	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1267753003319	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1267753003320	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1267753003321	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1267753003322	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1267753003323	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1267753003324	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
1267753003325	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1267753003326	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1267753003327	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1267753003328	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1267753003329	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1267753003330	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1267753003331	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
1267753003332	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1267753003333	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1267753003334	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1267753003335	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1267753003336	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1267753003337	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1267753003338	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1267753003339	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
1267753003340	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1267753003341	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
1267753003342	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
1267753003343	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
1267753003344	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
1267753003345	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1267753003346	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1267753003347	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1267753003348	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1267753003349	hypothetical protein; Provisional; Region: PRK11239
1267753003350	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
1267753003351	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
1267753003352	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1267753003353	multidrug resistance protein MdtH; Provisional; Region: PRK11646
1267753003354	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753003355	putative substrate translocation pore; other site
1267753003356	glutaredoxin 2; Provisional; Region: PRK10387
1267753003357	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
1267753003358	C-terminal domain interface [polypeptide binding]; other site
1267753003359	GSH binding site (G-site) [chemical binding]; other site
1267753003360	catalytic residues [active]
1267753003361	putative dimer interface [polypeptide binding]; other site
1267753003362	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
1267753003363	N-terminal domain interface [polypeptide binding]; other site
1267753003364	lipoprotein; Provisional; Region: PRK10598
1267753003365	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1267753003366	active site
1267753003367	substrate binding pocket [chemical binding]; other site
1267753003368	dimer interface [polypeptide binding]; other site
1267753003369	DNA damage-inducible protein I; Provisional; Region: PRK10597
1267753003370	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
1267753003371	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
1267753003372	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1267753003373	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
1267753003374	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
1267753003375	hypothetical protein; Provisional; Region: PRK03757
1267753003376	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1267753003377	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1267753003378	active site residue [active]
1267753003379	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1267753003380	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1267753003381	putative acyl-acceptor binding pocket; other site
1267753003382	drug efflux system protein MdtG; Provisional; Region: PRK09874
1267753003383	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753003384	putative substrate translocation pore; other site
1267753003385	secY/secA suppressor protein; Provisional; Region: PRK11467
1267753003386	lipoprotein; Provisional; Region: PRK10175
1267753003387	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1267753003388	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
1267753003389	Ligand binding site; other site
1267753003390	DXD motif; other site
1267753003391	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
1267753003392	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
1267753003393	potential frameshift: common BLAST hit: gi|386591013|ref|YP_006087413.1| Glucans biosynthesis protein C
1267753003394	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
1267753003395	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
1267753003396	putative active site [active]
1267753003397	catalytic site [active]
1267753003398	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
1267753003399	putative active site [active]
1267753003400	catalytic site [active]
1267753003401	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1267753003402	putative ADP-ribose binding site [chemical binding]; other site
1267753003403	putative active site [active]
1267753003404	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1267753003405	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
1267753003406	major curlin subunit; Provisional; Region: csgA; PRK10051
1267753003407	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1267753003408	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
1267753003409	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1267753003410	Curlin associated repeat; Region: Curlin_rpt; pfam07012
1267753003411	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
1267753003412	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753003413	DNA binding residues [nucleotide binding]
1267753003414	dimerization interface [polypeptide binding]; other site
1267753003415	curli assembly protein CsgE; Provisional; Region: PRK10386
1267753003416	curli assembly protein CsgF; Provisional; Region: PRK10050
1267753003417	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
1267753003418	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
1267753003419	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1267753003420	putative hydrolase; Validated; Region: PRK09248
1267753003421	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1267753003422	active site
1267753003423	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
1267753003424	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
1267753003425	putative ligand binding site [chemical binding]; other site
1267753003426	NAD binding site [chemical binding]; other site
1267753003427	dimerization interface [polypeptide binding]; other site
1267753003428	catalytic site [active]
1267753003429	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1267753003430	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1267753003431	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1267753003432	putative sialic acid transporter; Provisional; Region: PRK12307
1267753003433	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753003434	putative substrate translocation pore; other site
1267753003435	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1267753003436	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
1267753003437	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
1267753003438	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1267753003439	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1267753003440	putative active site cavity [active]
1267753003441	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
1267753003442	Na binding site [ion binding]; other site
1267753003443	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1267753003444	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1267753003445	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1267753003446	putative active site [active]
1267753003447	hypothetical protein; Provisional; Region: PRK10536
1267753003448	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1267753003449	Domain of unknown function (DUF4040); Region: DUF4040; cl00676
1267753003450	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1267753003451	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1267753003452	Na binding site [ion binding]; other site
1267753003453	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
1267753003454	Predicted transcriptional regulator [Transcription]; Region: COG3905
1267753003455	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1267753003456	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1267753003457	Glutamate binding site [chemical binding]; other site
1267753003458	NAD binding site [chemical binding]; other site
1267753003459	catalytic residues [active]
1267753003460	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
1267753003461	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
1267753003462	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753003463	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
1267753003464	General stress protein [General function prediction only]; Region: GsiB; COG3729
1267753003465	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
1267753003466	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1267753003467	hypothetical protein; Provisional; Region: PRK10174
1267753003468	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
1267753003469	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1267753003470	catalytic core [active]
1267753003471	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
1267753003472	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
1267753003473	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1267753003474	catalytic residues [active]
1267753003475	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
1267753003476	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1267753003477	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1267753003478	catalytic residues [active]
1267753003479	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
1267753003480	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1267753003481	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1267753003482	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1267753003483	DsbD alpha interface [polypeptide binding]; other site
1267753003484	catalytic residues [active]
1267753003485	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
1267753003486	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1267753003487	HSP70 interaction site [polypeptide binding]; other site
1267753003488	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1267753003489	substrate binding site [polypeptide binding]; other site
1267753003490	dimer interface [polypeptide binding]; other site
1267753003491	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
1267753003492	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
1267753003493	anti-adapter protein IraM; Provisional; Region: PRK09919
1267753003494	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
1267753003495	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
1267753003496	Cupin domain; Region: Cupin_2; pfam07883
1267753003497	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753003498	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753003499	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1267753003500	putative substrate translocation pore; other site
1267753003501	2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Region: HpaI; TIGR02311
1267753003502	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
1267753003503	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
1267753003504	putative substrate binding pocket [chemical binding]; other site
1267753003505	trimer interface [polypeptide binding]; other site
1267753003506	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
1267753003507	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1267753003508	putative active site [active]
1267753003509	putative metal binding site [ion binding]; other site
1267753003510	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
1267753003511	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
1267753003512	NAD binding site [chemical binding]; other site
1267753003513	catalytic residues [active]
1267753003514	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
1267753003515	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
1267753003516	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1267753003517	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
1267753003518	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1267753003519	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
1267753003520	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
1267753003521	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
1267753003522	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1267753003523	active site
1267753003524	homotetramer interface [polypeptide binding]; other site
1267753003525	Response regulator receiver domain; Region: Response_reg; pfam00072
1267753003526	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753003527	active site
1267753003528	phosphorylation site [posttranslational modification]
1267753003529	intermolecular recognition site; other site
1267753003530	dimerization interface [polypeptide binding]; other site
1267753003531	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1267753003532	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1267753003533	HAMP domain; Region: HAMP; pfam00672
1267753003534	dimerization interface [polypeptide binding]; other site
1267753003535	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753003536	dimer interface [polypeptide binding]; other site
1267753003537	phosphorylation site [posttranslational modification]
1267753003538	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753003539	ATP binding site [chemical binding]; other site
1267753003540	Mg2+ binding site [ion binding]; other site
1267753003541	G-X-G motif; other site
1267753003542	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
1267753003543	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
1267753003544	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
1267753003545	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
1267753003546	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
1267753003547	secreted effector protein PipB; Provisional; Region: PRK15197
1267753003548	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1267753003549	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1267753003550	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1267753003551	PipA protein; Region: PipA; pfam07108
1267753003552	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1267753003553	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
1267753003554	ADP-ribose binding site [chemical binding]; other site
1267753003555	Phage Tail Collar Domain; Region: Collar; pfam07484
1267753003556	Baseplate J-like protein; Region: Baseplate_J; cl01294
1267753003557	virion protein; Provisional; Region: V; PHA02564
1267753003558	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1267753003559	active site
1267753003560	metal binding site [ion binding]; metal-binding site
1267753003561	Uncharacterized protein conserved in bacteria (DUF2184); Region: DUF2184; pfam09950
1267753003562	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1267753003563	nudix motif; other site
1267753003564	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
1267753003565	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
1267753003566	Terminase-like family; Region: Terminase_6; pfam03237
1267753003567	Terminase small subunit; Region: Terminase_2; pfam03592
1267753003568	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
1267753003569	Predicted chitinase [General function prediction only]; Region: COG3179
1267753003570	catalytic residue [active]
1267753003571	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
1267753003572	PipA protein; Region: PipA; pfam07108
1267753003573	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
1267753003574	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1267753003575	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1267753003576	MT-A70; Region: MT-A70; cl01947
1267753003577	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1267753003578	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1267753003579	replicative DNA helicase; Region: DnaB; TIGR00665
1267753003580	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1267753003581	Walker A motif; other site
1267753003582	ATP binding site [chemical binding]; other site
1267753003583	Walker B motif; other site
1267753003584	DNA binding loops [nucleotide binding]
1267753003585	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
1267753003586	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753003587	non-specific DNA binding site [nucleotide binding]; other site
1267753003588	salt bridge; other site
1267753003589	sequence-specific DNA binding site [nucleotide binding]; other site
1267753003590	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753003591	non-specific DNA binding site [nucleotide binding]; other site
1267753003592	salt bridge; other site
1267753003593	sequence-specific DNA binding site [nucleotide binding]; other site
1267753003594	exonuclease VIII; Reviewed; Region: PRK09709
1267753003595	exonuclease VIII; Reviewed; Region: PRK09709
1267753003596	Siphovirus Gp157; Region: Sipho_Gp157; pfam05565
1267753003597	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
1267753003598	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753003599	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753003600	active site
1267753003601	DNA binding site [nucleotide binding]
1267753003602	Int/Topo IB signature motif; other site
1267753003603	Nucleoid-associated protein [General function prediction only]; Region: COG3081
1267753003604	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
1267753003605	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1267753003606	YccA-like proteins; Region: YccA_like; cd10433
1267753003607	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
1267753003608	sulfur transfer protein TusE; Provisional; Region: PRK11508
1267753003609	acylphosphatase; Provisional; Region: PRK14426
1267753003610	Cupin domain; Region: Cupin_2; cl17218
1267753003611	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1267753003612	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753003613	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1267753003614	substrate binding site [chemical binding]; other site
1267753003615	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
1267753003616	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
1267753003617	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1267753003618	putative RNA binding site [nucleotide binding]; other site
1267753003619	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753003620	S-adenosylmethionine binding site [chemical binding]; other site
1267753003621	heat shock protein HspQ; Provisional; Region: PRK14129
1267753003622	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1267753003623	hypothetical protein; Provisional; Region: PRK03641
1267753003624	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
1267753003625	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1267753003626	active site
1267753003627	dimer interfaces [polypeptide binding]; other site
1267753003628	catalytic residues [active]
1267753003629	DNA helicase IV; Provisional; Region: helD; PRK11054
1267753003630	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
1267753003631	Part of AAA domain; Region: AAA_19; pfam13245
1267753003632	Family description; Region: UvrD_C_2; pfam13538
1267753003633	Predicted membrane protein [Function unknown]; Region: COG3304
1267753003634	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1267753003635	Domain of unknown function (DUF307); Region: DUF307; pfam03733
1267753003636	TIGR01666 family membrane protein; Region: YCCS
1267753003637	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1267753003638	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1267753003639	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
1267753003640	TfoX C-terminal domain; Region: TfoX_C; pfam04994
1267753003641	cell division inhibitor SulA; Region: sula; TIGR00623
1267753003642	outer membrane protein A; Reviewed; Region: PRK10808
1267753003643	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
1267753003644	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1267753003645	ligand binding site [chemical binding]; other site
1267753003646	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
1267753003647	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
1267753003648	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1267753003649	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
1267753003650	active site 1 [active]
1267753003651	dimer interface [polypeptide binding]; other site
1267753003652	active site 2 [active]
1267753003653	ribosome modulation factor; Provisional; Region: PRK14563
1267753003654	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
1267753003655	Protein of unknown function (DUF330); Region: DUF330; pfam03886
1267753003656	paraquat-inducible protein B; Provisional; Region: PRK10807
1267753003657	mce related protein; Region: MCE; pfam02470
1267753003658	mce related protein; Region: MCE; pfam02470
1267753003659	mce related protein; Region: MCE; pfam02470
1267753003660	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
1267753003661	Paraquat-inducible protein A; Region: PqiA; pfam04403
1267753003662	Paraquat-inducible protein A; Region: PqiA; pfam04403
1267753003663	ABC transporter ATPase component; Reviewed; Region: PRK11147
1267753003664	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753003665	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753003666	Walker A/P-loop; other site
1267753003667	Walker A/P-loop; other site
1267753003668	ATP binding site [chemical binding]; other site
1267753003669	ATP binding site [chemical binding]; other site
1267753003670	Q-loop/lid; other site
1267753003671	Q-loop/lid; other site
1267753003672	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753003673	ABC transporter signature motif; other site
1267753003674	Walker B; other site
1267753003675	D-loop; other site
1267753003676	ABC transporter; Region: ABC_tran_2; pfam12848
1267753003677	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753003678	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
1267753003679	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1267753003680	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
1267753003681	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753003682	S-adenosylmethionine binding site [chemical binding]; other site
1267753003683	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
1267753003684	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
1267753003685	MOSC domain; Region: MOSC; pfam03473
1267753003686	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1267753003687	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1267753003688	catalytic loop [active]
1267753003689	iron binding site [ion binding]; other site
1267753003690	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
1267753003691	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1267753003692	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1267753003693	quinone interaction residues [chemical binding]; other site
1267753003694	active site
1267753003695	catalytic residues [active]
1267753003696	FMN binding site [chemical binding]; other site
1267753003697	substrate binding site [chemical binding]; other site
1267753003698	aminopeptidase N; Provisional; Region: pepN; PRK14015
1267753003699	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
1267753003700	active site
1267753003701	Zn binding site [ion binding]; other site
1267753003702	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
1267753003703	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
1267753003704	active site
1267753003705	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1267753003706	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1267753003707	putative dimer interface [polypeptide binding]; other site
1267753003708	putative anticodon binding site; other site
1267753003709	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1267753003710	homodimer interface [polypeptide binding]; other site
1267753003711	motif 1; other site
1267753003712	motif 2; other site
1267753003713	active site
1267753003714	motif 3; other site
1267753003715	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1267753003716	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1267753003717	trimer interface [polypeptide binding]; other site
1267753003718	eyelet of channel; other site
1267753003719	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1267753003720	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753003721	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753003722	homodimer interface [polypeptide binding]; other site
1267753003723	catalytic residue [active]
1267753003724	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1267753003725	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
1267753003726	Peptidase M15; Region: Peptidase_M15_3; cl01194
1267753003727	murein L,D-transpeptidase; Provisional; Region: PRK10594
1267753003728	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1267753003729	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1267753003730	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1267753003731	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
1267753003732	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1267753003733	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
1267753003734	condesin subunit E; Provisional; Region: PRK05256
1267753003735	condesin subunit F; Provisional; Region: PRK05260
1267753003736	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1267753003737	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753003738	S-adenosylmethionine binding site [chemical binding]; other site
1267753003739	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1267753003740	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1267753003741	putative active site [active]
1267753003742	hypothetical protein; Provisional; Region: PRK10593
1267753003743	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1267753003744	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1267753003745	Ligand binding site; other site
1267753003746	oligomer interface; other site
1267753003747	hypothetical protein; Provisional; Region: PRK11827
1267753003748	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
1267753003749	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
1267753003750	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1267753003751	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1267753003752	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
1267753003753	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1267753003754	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1267753003755	Walker A/P-loop; other site
1267753003756	ATP binding site [chemical binding]; other site
1267753003757	Q-loop/lid; other site
1267753003758	ABC transporter signature motif; other site
1267753003759	Walker B; other site
1267753003760	D-loop; other site
1267753003761	H-loop/switch region; other site
1267753003762	ComEC family competence protein; Provisional; Region: PRK11539
1267753003763	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1267753003764	Competence protein; Region: Competence; pfam03772
1267753003765	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1267753003766	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1267753003767	IHF dimer interface [polypeptide binding]; other site
1267753003768	IHF - DNA interface [nucleotide binding]; other site
1267753003769	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1267753003770	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1267753003771	RNA binding site [nucleotide binding]; other site
1267753003772	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1267753003773	RNA binding site [nucleotide binding]; other site
1267753003774	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
1267753003775	RNA binding site [nucleotide binding]; other site
1267753003776	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
1267753003777	RNA binding site [nucleotide binding]; other site
1267753003778	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
1267753003779	RNA binding site [nucleotide binding]; other site
1267753003780	cytidylate kinase; Provisional; Region: cmk; PRK00023
1267753003781	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1267753003782	CMP-binding site; other site
1267753003783	The sites determining sugar specificity; other site
1267753003784	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1267753003785	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1267753003786	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
1267753003787	hinge; other site
1267753003788	active site
1267753003789	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1267753003790	homodimer interface [polypeptide binding]; other site
1267753003791	substrate-cofactor binding pocket; other site
1267753003792	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753003793	catalytic residue [active]
1267753003794	Predicted membrane protein [Function unknown]; Region: COG2323
1267753003795	uncharacterized domain; Region: TIGR00702
1267753003796	YcaO-like family; Region: YcaO; pfam02624
1267753003797	formate transporter; Provisional; Region: PRK10805
1267753003798	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1267753003799	Pyruvate formate lyase 1; Region: PFL1; cd01678
1267753003800	coenzyme A binding site [chemical binding]; other site
1267753003801	active site
1267753003802	catalytic residues [active]
1267753003803	glycine loop; other site
1267753003804	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
1267753003805	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753003806	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
1267753003807	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753003808	FeS/SAM binding site; other site
1267753003809	inner membrane transporter YjeM; Provisional; Region: PRK15238
1267753003810	putative MFS family transporter protein; Provisional; Region: PRK03633
1267753003811	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753003812	putative substrate translocation pore; other site
1267753003813	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
1267753003814	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1267753003815	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753003816	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
1267753003817	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1267753003818	putative [Fe4-S4] binding site [ion binding]; other site
1267753003819	putative molybdopterin cofactor binding site [chemical binding]; other site
1267753003820	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1267753003821	putative molybdopterin cofactor binding site; other site
1267753003822	seryl-tRNA synthetase; Provisional; Region: PRK05431
1267753003823	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1267753003824	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1267753003825	dimer interface [polypeptide binding]; other site
1267753003826	active site
1267753003827	motif 1; other site
1267753003828	motif 2; other site
1267753003829	motif 3; other site
1267753003830	recombination factor protein RarA; Reviewed; Region: PRK13342
1267753003831	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753003832	Walker A motif; other site
1267753003833	ATP binding site [chemical binding]; other site
1267753003834	Walker B motif; other site
1267753003835	arginine finger; other site
1267753003836	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1267753003837	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
1267753003838	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1267753003839	DNA translocase FtsK; Provisional; Region: PRK10263
1267753003840	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1267753003841	DNA translocase FtsK; Provisional; Region: PRK10263
1267753003842	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1267753003843	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1267753003844	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
1267753003845	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1267753003846	putative DNA binding site [nucleotide binding]; other site
1267753003847	putative Zn2+ binding site [ion binding]; other site
1267753003848	AsnC family; Region: AsnC_trans_reg; pfam01037
1267753003849	thioredoxin reductase; Provisional; Region: PRK10262
1267753003850	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1267753003851	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753003852	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
1267753003853	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1267753003854	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753003855	Walker A/P-loop; other site
1267753003856	ATP binding site [chemical binding]; other site
1267753003857	Q-loop/lid; other site
1267753003858	ABC transporter signature motif; other site
1267753003859	Walker B; other site
1267753003860	D-loop; other site
1267753003861	H-loop/switch region; other site
1267753003862	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
1267753003863	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1267753003864	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753003865	Walker A/P-loop; other site
1267753003866	ATP binding site [chemical binding]; other site
1267753003867	Q-loop/lid; other site
1267753003868	ABC transporter signature motif; other site
1267753003869	Walker B; other site
1267753003870	D-loop; other site
1267753003871	H-loop/switch region; other site
1267753003872	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1267753003873	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1267753003874	rRNA binding site [nucleotide binding]; other site
1267753003875	predicted 30S ribosome binding site; other site
1267753003876	LysR family transcriptional regulator; Provisional; Region: PRK14997
1267753003877	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753003878	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
1267753003879	putative effector binding pocket; other site
1267753003880	putative dimerization interface [polypeptide binding]; other site
1267753003881	Pirin-related protein [General function prediction only]; Region: COG1741
1267753003882	Pirin; Region: Pirin; pfam02678
1267753003883	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1267753003884	Isochorismatase family; Region: Isochorismatase; pfam00857
1267753003885	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1267753003886	catalytic triad [active]
1267753003887	dimer interface [polypeptide binding]; other site
1267753003888	conserved cis-peptide bond; other site
1267753003889	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
1267753003890	Clp amino terminal domain; Region: Clp_N; pfam02861
1267753003891	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753003892	Walker A motif; other site
1267753003893	ATP binding site [chemical binding]; other site
1267753003894	Walker B motif; other site
1267753003895	arginine finger; other site
1267753003896	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753003897	Walker A motif; other site
1267753003898	ATP binding site [chemical binding]; other site
1267753003899	Walker B motif; other site
1267753003900	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1267753003901	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
1267753003902	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1267753003903	DNA-binding site [nucleotide binding]; DNA binding site
1267753003904	RNA-binding motif; other site
1267753003905	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1267753003906	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1267753003907	Walker A/P-loop; other site
1267753003908	ATP binding site [chemical binding]; other site
1267753003909	Q-loop/lid; other site
1267753003910	ABC transporter signature motif; other site
1267753003911	Walker B; other site
1267753003912	D-loop; other site
1267753003913	H-loop/switch region; other site
1267753003914	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1267753003915	FtsX-like permease family; Region: FtsX; pfam02687
1267753003916	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1267753003917	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753003918	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753003919	Protein of unknown function (DUF535); Region: DUF535; pfam04393
1267753003920	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
1267753003921	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1267753003922	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1267753003923	putative active site [active]
1267753003924	putative metal-binding site [ion binding]; other site
1267753003925	Predicted membrane protein [Function unknown]; Region: COG2431
1267753003926	hybrid cluster protein; Provisional; Region: PRK05290
1267753003927	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1267753003928	ACS interaction site; other site
1267753003929	CODH interaction site; other site
1267753003930	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1267753003931	hybrid metal cluster; other site
1267753003932	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
1267753003933	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
1267753003934	FAD binding pocket [chemical binding]; other site
1267753003935	FAD binding motif [chemical binding]; other site
1267753003936	phosphate binding motif [ion binding]; other site
1267753003937	beta-alpha-beta structure motif; other site
1267753003938	NAD binding pocket [chemical binding]; other site
1267753003939	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1267753003940	catalytic loop [active]
1267753003941	iron binding site [ion binding]; other site
1267753003942	pyruvate dehydrogenase; Provisional; Region: PRK09124
1267753003943	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
1267753003944	PYR/PP interface [polypeptide binding]; other site
1267753003945	dimer interface [polypeptide binding]; other site
1267753003946	tetramer interface [polypeptide binding]; other site
1267753003947	TPP binding site [chemical binding]; other site
1267753003948	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1267753003949	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
1267753003950	TPP-binding site [chemical binding]; other site
1267753003951	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1267753003952	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1267753003953	tetramer interface [polypeptide binding]; other site
1267753003954	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753003955	catalytic residue [active]
1267753003956	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1267753003957	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
1267753003958	putative NAD(P) binding site [chemical binding]; other site
1267753003959	putative active site [active]
1267753003960	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
1267753003961	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1267753003962	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1267753003963	NAD(P) binding site [chemical binding]; other site
1267753003964	active site
1267753003965	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1267753003966	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1267753003967	amidase catalytic site [active]
1267753003968	Zn binding residues [ion binding]; other site
1267753003969	substrate binding site [chemical binding]; other site
1267753003970	hypothetical protein; Provisional; Region: PRK02877
1267753003971	putative lipoprotein; Provisional; Region: PRK10533
1267753003972	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
1267753003973	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753003974	Walker A/P-loop; other site
1267753003975	ATP binding site [chemical binding]; other site
1267753003976	Q-loop/lid; other site
1267753003977	ABC transporter signature motif; other site
1267753003978	Walker B; other site
1267753003979	D-loop; other site
1267753003980	H-loop/switch region; other site
1267753003981	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1267753003982	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753003983	substrate binding pocket [chemical binding]; other site
1267753003984	membrane-bound complex binding site; other site
1267753003985	hinge residues; other site
1267753003986	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1267753003987	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753003988	dimer interface [polypeptide binding]; other site
1267753003989	conserved gate region; other site
1267753003990	putative PBP binding loops; other site
1267753003991	ABC-ATPase subunit interface; other site
1267753003992	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753003993	dimer interface [polypeptide binding]; other site
1267753003994	conserved gate region; other site
1267753003995	putative PBP binding loops; other site
1267753003996	ABC-ATPase subunit interface; other site
1267753003997	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1267753003998	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753003999	substrate binding pocket [chemical binding]; other site
1267753004000	membrane-bound complex binding site; other site
1267753004001	hinge residues; other site
1267753004002	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1267753004003	Sulfatase; Region: Sulfatase; cl17466
1267753004004	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1267753004005	active site
1267753004006	P-loop; other site
1267753004007	phosphorylation site [posttranslational modification]
1267753004008	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1267753004009	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
1267753004010	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753004011	S-adenosylmethionine binding site [chemical binding]; other site
1267753004012	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
1267753004013	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1267753004014	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753004015	dimer interface [polypeptide binding]; other site
1267753004016	conserved gate region; other site
1267753004017	putative PBP binding loops; other site
1267753004018	ABC-ATPase subunit interface; other site
1267753004019	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753004020	dimer interface [polypeptide binding]; other site
1267753004021	conserved gate region; other site
1267753004022	putative PBP binding loops; other site
1267753004023	ABC-ATPase subunit interface; other site
1267753004024	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
1267753004025	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753004026	Walker A/P-loop; other site
1267753004027	ATP binding site [chemical binding]; other site
1267753004028	Q-loop/lid; other site
1267753004029	ABC transporter signature motif; other site
1267753004030	Walker B; other site
1267753004031	D-loop; other site
1267753004032	H-loop/switch region; other site
1267753004033	TOBE domain; Region: TOBE_2; pfam08402
1267753004034	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
1267753004035	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1267753004036	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1267753004037	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1267753004038	RimK-like ATP-grasp domain; Region: RimK; pfam08443
1267753004039	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1267753004040	dimer interface [polypeptide binding]; other site
1267753004041	FMN binding site [chemical binding]; other site
1267753004042	NADPH bind site [chemical binding]; other site
1267753004043	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
1267753004044	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
1267753004045	GSH binding site [chemical binding]; other site
1267753004046	catalytic residues [active]
1267753004047	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
1267753004048	putative transporter; Provisional; Region: PRK04972
1267753004049	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1267753004050	TrkA-C domain; Region: TrkA_C; pfam02080
1267753004051	TrkA-C domain; Region: TrkA_C; pfam02080
1267753004052	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1267753004053	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
1267753004054	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753004055	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
1267753004056	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753004057	putative substrate translocation pore; other site
1267753004058	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1267753004059	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
1267753004060	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753004061	active site
1267753004062	motif I; other site
1267753004063	motif II; other site
1267753004064	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753004065	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
1267753004066	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753004067	putative substrate translocation pore; other site
1267753004068	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1267753004069	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
1267753004070	active site
1267753004071	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1267753004072	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1267753004073	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753004074	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
1267753004075	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1267753004076	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1267753004077	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1267753004078	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
1267753004079	putative C-terminal domain interface [polypeptide binding]; other site
1267753004080	putative GSH binding site (G-site) [chemical binding]; other site
1267753004081	putative dimer interface [polypeptide binding]; other site
1267753004082	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
1267753004083	putative N-terminal domain interface [polypeptide binding]; other site
1267753004084	putative dimer interface [polypeptide binding]; other site
1267753004085	putative substrate binding pocket (H-site) [chemical binding]; other site
1267753004086	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1267753004087	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
1267753004088	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
1267753004089	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
1267753004090	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
1267753004091	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1267753004092	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753004093	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753004094	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
1267753004095	putative dimerization interface [polypeptide binding]; other site
1267753004096	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
1267753004097	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1267753004098	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
1267753004099	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
1267753004100	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1267753004101	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1267753004102	active site
1267753004103	Uncharacterized conserved protein [Function unknown]; Region: COG3777
1267753004104	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1267753004105	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1267753004106	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1267753004107	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1267753004108	Ligand binding site [chemical binding]; other site
1267753004109	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1267753004110	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1267753004111	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
1267753004112	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
1267753004113	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1267753004114	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753004115	FeS/SAM binding site; other site
1267753004116	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
1267753004117	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1267753004118	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753004119	dimer interface [polypeptide binding]; other site
1267753004120	conserved gate region; other site
1267753004121	putative PBP binding loops; other site
1267753004122	ABC-ATPase subunit interface; other site
1267753004123	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
1267753004124	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753004125	dimer interface [polypeptide binding]; other site
1267753004126	conserved gate region; other site
1267753004127	putative PBP binding loops; other site
1267753004128	ABC-ATPase subunit interface; other site
1267753004129	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
1267753004130	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
1267753004131	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
1267753004132	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753004133	Walker A/P-loop; other site
1267753004134	ATP binding site [chemical binding]; other site
1267753004135	Q-loop/lid; other site
1267753004136	ABC transporter signature motif; other site
1267753004137	Walker B; other site
1267753004138	D-loop; other site
1267753004139	H-loop/switch region; other site
1267753004140	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1267753004141	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753004142	Walker A/P-loop; other site
1267753004143	ATP binding site [chemical binding]; other site
1267753004144	Q-loop/lid; other site
1267753004145	ABC transporter signature motif; other site
1267753004146	Walker B; other site
1267753004147	D-loop; other site
1267753004148	H-loop/switch region; other site
1267753004149	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1267753004150	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
1267753004151	catalytic nucleophile [active]
1267753004152	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
1267753004153	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1267753004154	dimer interface [polypeptide binding]; other site
1267753004155	putative functional site; other site
1267753004156	putative MPT binding site; other site
1267753004157	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
1267753004158	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1267753004159	ATP binding site [chemical binding]; other site
1267753004160	substrate interface [chemical binding]; other site
1267753004161	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
1267753004162	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753004163	FeS/SAM binding site; other site
1267753004164	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
1267753004165	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1267753004166	dimer interface [polypeptide binding]; other site
1267753004167	active site
1267753004168	glycine loop; other site
1267753004169	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
1267753004170	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753004171	active site
1267753004172	motif I; other site
1267753004173	motif II; other site
1267753004174	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753004175	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
1267753004176	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1267753004177	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753004178	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753004179	Walker A/P-loop; other site
1267753004180	ATP binding site [chemical binding]; other site
1267753004181	ABC transporter signature motif; other site
1267753004182	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753004183	Walker B; other site
1267753004184	ABC transporter; Region: ABC_tran_2; pfam12848
1267753004185	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753004186	L,D-transpeptidase; Provisional; Region: PRK10260
1267753004187	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1267753004188	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
1267753004189	transmembrane helices; other site
1267753004190	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1267753004191	manganese transport regulator MntR; Provisional; Region: PRK11050
1267753004192	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1267753004193	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1267753004194	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1267753004195	Sulfatase; Region: Sulfatase; pfam00884
1267753004196	outer membrane protein X; Provisional; Region: ompX; PRK09408
1267753004197	threonine and homoserine efflux system; Provisional; Region: PRK10532
1267753004198	EamA-like transporter family; Region: EamA; pfam00892
1267753004199	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1267753004200	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1267753004201	dimerization interface [polypeptide binding]; other site
1267753004202	DPS ferroxidase diiron center [ion binding]; other site
1267753004203	ion pore; other site
1267753004204	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
1267753004205	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753004206	substrate binding pocket [chemical binding]; other site
1267753004207	membrane-bound complex binding site; other site
1267753004208	hinge residues; other site
1267753004209	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1267753004210	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753004211	dimer interface [polypeptide binding]; other site
1267753004212	conserved gate region; other site
1267753004213	putative PBP binding loops; other site
1267753004214	ABC-ATPase subunit interface; other site
1267753004215	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
1267753004216	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1267753004217	Walker A/P-loop; other site
1267753004218	ATP binding site [chemical binding]; other site
1267753004219	Q-loop/lid; other site
1267753004220	ABC transporter signature motif; other site
1267753004221	Walker B; other site
1267753004222	D-loop; other site
1267753004223	H-loop/switch region; other site
1267753004224	putative mechanosensitive channel protein; Provisional; Region: PRK11465
1267753004225	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1267753004226	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
1267753004227	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1267753004228	hypothetical protein; Provisional; Region: PRK11019
1267753004229	hypothetical protein; Provisional; Region: PRK10259
1267753004230	glycosyl transferase family protein; Provisional; Region: PRK08136
1267753004231	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1267753004232	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
1267753004233	DEAD_2; Region: DEAD_2; pfam06733
1267753004234	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1267753004235	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1267753004236	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1267753004237	ATP binding site [chemical binding]; other site
1267753004238	Mg++ binding site [ion binding]; other site
1267753004239	motif III; other site
1267753004240	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753004241	nucleotide binding region [chemical binding]; other site
1267753004242	ATP-binding site [chemical binding]; other site
1267753004243	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
1267753004244	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753004245	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
1267753004246	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
1267753004247	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753004248	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753004249	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1267753004250	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1267753004251	Walker A/P-loop; other site
1267753004252	ATP binding site [chemical binding]; other site
1267753004253	Q-loop/lid; other site
1267753004254	ABC transporter signature motif; other site
1267753004255	Walker B; other site
1267753004256	D-loop; other site
1267753004257	H-loop/switch region; other site
1267753004258	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
1267753004259	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1267753004260	Walker A/P-loop; other site
1267753004261	ATP binding site [chemical binding]; other site
1267753004262	Q-loop/lid; other site
1267753004263	ABC transporter signature motif; other site
1267753004264	Walker B; other site
1267753004265	D-loop; other site
1267753004266	H-loop/switch region; other site
1267753004267	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1267753004268	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1267753004269	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1267753004270	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1267753004271	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
1267753004272	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
1267753004273	putative catalytic site [active]
1267753004274	putative metal binding site [ion binding]; other site
1267753004275	putative phosphate binding site [ion binding]; other site
1267753004276	cardiolipin synthase 2; Provisional; Region: PRK11263
1267753004277	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1267753004278	putative active site [active]
1267753004279	catalytic site [active]
1267753004280	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
1267753004281	putative active site [active]
1267753004282	catalytic site [active]
1267753004283	Predicted integral membrane protein [Function unknown]; Region: COG0392
1267753004284	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1267753004285	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1267753004286	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1267753004287	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1267753004288	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1267753004289	MoaE homodimer interface [polypeptide binding]; other site
1267753004290	MoaD interaction [polypeptide binding]; other site
1267753004291	active site residues [active]
1267753004292	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1267753004293	MoaE interaction surface [polypeptide binding]; other site
1267753004294	MoeB interaction surface [polypeptide binding]; other site
1267753004295	thiocarboxylated glycine; other site
1267753004296	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1267753004297	trimer interface [polypeptide binding]; other site
1267753004298	dimer interface [polypeptide binding]; other site
1267753004299	putative active site [active]
1267753004300	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1267753004301	MPT binding site; other site
1267753004302	trimer interface [polypeptide binding]; other site
1267753004303	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1267753004304	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753004305	FeS/SAM binding site; other site
1267753004306	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1267753004307	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1267753004308	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1267753004309	putative substrate binding pocket [chemical binding]; other site
1267753004310	dimer interface [polypeptide binding]; other site
1267753004311	phosphate binding site [ion binding]; other site
1267753004312	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
1267753004313	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
1267753004314	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1267753004315	Leucine-rich repeats; other site
1267753004316	Substrate binding site [chemical binding]; other site
1267753004317	excinuclease ABC subunit B; Provisional; Region: PRK05298
1267753004318	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753004319	ATP binding site [chemical binding]; other site
1267753004320	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753004321	nucleotide binding region [chemical binding]; other site
1267753004322	ATP-binding site [chemical binding]; other site
1267753004323	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1267753004324	UvrB/uvrC motif; Region: UVR; pfam02151
1267753004325	AAA domain; Region: AAA_26; pfam13500
1267753004326	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1267753004327	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1267753004328	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753004329	S-adenosylmethionine binding site [chemical binding]; other site
1267753004330	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1267753004331	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1267753004332	substrate-cofactor binding pocket; other site
1267753004333	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753004334	catalytic residue [active]
1267753004335	biotin synthase; Provisional; Region: PRK15108
1267753004336	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753004337	FeS/SAM binding site; other site
1267753004338	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1267753004339	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
1267753004340	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1267753004341	inhibitor-cofactor binding pocket; inhibition site
1267753004342	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753004343	catalytic residue [active]
1267753004344	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
1267753004345	substrate binding site [chemical binding]; other site
1267753004346	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1267753004347	active sites [active]
1267753004348	tetramer interface [polypeptide binding]; other site
1267753004349	urocanate hydratase; Provisional; Region: PRK05414
1267753004350	histidine utilization repressor; Provisional; Region: PRK14999
1267753004351	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753004352	DNA-binding site [nucleotide binding]; DNA binding site
1267753004353	UTRA domain; Region: UTRA; pfam07702
1267753004354	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1267753004355	putative active site [active]
1267753004356	putative metal binding site [ion binding]; other site
1267753004357	imidazolonepropionase; Validated; Region: PRK09356
1267753004358	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1267753004359	active site
1267753004360	acyl-CoA thioesterase; Provisional; Region: PRK10531
1267753004361	putative pectinesterase; Region: PLN02432; cl01911
1267753004362	6-phosphogluconolactonase; Provisional; Region: PRK11028
1267753004363	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1267753004364	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1267753004365	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753004366	active site
1267753004367	motif I; other site
1267753004368	motif II; other site
1267753004369	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1267753004370	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1267753004371	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1267753004372	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
1267753004373	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
1267753004374	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753004375	Walker A/P-loop; other site
1267753004376	ATP binding site [chemical binding]; other site
1267753004377	Q-loop/lid; other site
1267753004378	ABC transporter signature motif; other site
1267753004379	Walker B; other site
1267753004380	D-loop; other site
1267753004381	H-loop/switch region; other site
1267753004382	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1267753004383	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1267753004384	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753004385	dimer interface [polypeptide binding]; other site
1267753004386	conserved gate region; other site
1267753004387	putative PBP binding loops; other site
1267753004388	ABC-ATPase subunit interface; other site
1267753004389	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
1267753004390	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753004391	substrate binding pocket [chemical binding]; other site
1267753004392	membrane-bound complex binding site; other site
1267753004393	hinge residues; other site
1267753004394	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
1267753004395	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
1267753004396	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1267753004397	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1267753004398	TOBE domain; Region: TOBE; pfam03459
1267753004399	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
1267753004400	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753004401	Walker A/P-loop; other site
1267753004402	ATP binding site [chemical binding]; other site
1267753004403	ABC transporter signature motif; other site
1267753004404	Walker B; other site
1267753004405	D-loop; other site
1267753004406	H-loop/switch region; other site
1267753004407	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753004408	Walker A/P-loop; other site
1267753004409	ATP binding site [chemical binding]; other site
1267753004410	Q-loop/lid; other site
1267753004411	ABC transporter signature motif; other site
1267753004412	Walker B; other site
1267753004413	D-loop; other site
1267753004414	H-loop/switch region; other site
1267753004415	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
1267753004416	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
1267753004417	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1267753004418	NAD binding site [chemical binding]; other site
1267753004419	homodimer interface [polypeptide binding]; other site
1267753004420	active site
1267753004421	substrate binding site [chemical binding]; other site
1267753004422	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
1267753004423	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
1267753004424	dimer interface [polypeptide binding]; other site
1267753004425	active site
1267753004426	galactokinase; Provisional; Region: PRK05101
1267753004427	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1267753004428	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1267753004429	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1267753004430	active site
1267753004431	catalytic residues [active]
1267753004432	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1267753004433	catalytic core [active]
1267753004434	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1267753004435	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1267753004436	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1267753004437	Walker A/P-loop; other site
1267753004438	ATP binding site [chemical binding]; other site
1267753004439	Q-loop/lid; other site
1267753004440	ABC transporter signature motif; other site
1267753004441	Walker B; other site
1267753004442	D-loop; other site
1267753004443	H-loop/switch region; other site
1267753004444	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1267753004445	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1267753004446	dimer interface [polypeptide binding]; other site
1267753004447	putative PBP binding regions; other site
1267753004448	ABC-ATPase subunit  interface; other site
1267753004449	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1267753004450	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1267753004451	YbgS-like protein; Region: YbgS; pfam13985
1267753004452	zinc transporter ZitB; Provisional; Region: PRK03557
1267753004453	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1267753004454	quinolinate synthetase; Provisional; Region: PRK09375
1267753004455	tol-pal system protein YbgF; Provisional; Region: PRK10803
1267753004456	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1267753004457	Tetratricopeptide repeat; Region: TPR_6; pfam13174
1267753004458	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
1267753004459	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1267753004460	ligand binding site [chemical binding]; other site
1267753004461	translocation protein TolB; Provisional; Region: tolB; PRK03629
1267753004462	TolB amino-terminal domain; Region: TolB_N; pfam04052
1267753004463	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1267753004464	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1267753004465	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1267753004466	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
1267753004467	TolA C-terminal; Region: TolA; pfam06519
1267753004468	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1267753004469	colicin uptake protein TolR; Provisional; Region: PRK11024
1267753004470	colicin uptake protein TolQ; Provisional; Region: PRK10801
1267753004471	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1267753004472	active site
1267753004473	hypothetical protein; Provisional; Region: PRK10588
1267753004474	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
1267753004475	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
1267753004476	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1267753004477	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1267753004478	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
1267753004479	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1267753004480	CoA binding domain; Region: CoA_binding; smart00881
1267753004481	CoA-ligase; Region: Ligase_CoA; pfam00549
1267753004482	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1267753004483	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1267753004484	CoA-ligase; Region: Ligase_CoA; pfam00549
1267753004485	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1267753004486	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1267753004487	E3 interaction surface; other site
1267753004488	lipoyl attachment site [posttranslational modification]; other site
1267753004489	e3 binding domain; Region: E3_binding; pfam02817
1267753004490	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1267753004491	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1267753004492	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1267753004493	TPP-binding site [chemical binding]; other site
1267753004494	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1267753004495	dimer interface [polypeptide binding]; other site
1267753004496	PYR/PP interface [polypeptide binding]; other site
1267753004497	TPP binding site [chemical binding]; other site
1267753004498	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
1267753004499	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1267753004500	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
1267753004501	L-aspartate oxidase; Provisional; Region: PRK06175
1267753004502	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1267753004503	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
1267753004504	SdhC subunit interface [polypeptide binding]; other site
1267753004505	proximal heme binding site [chemical binding]; other site
1267753004506	cardiolipin binding site; other site
1267753004507	Iron-sulfur protein interface; other site
1267753004508	proximal quinone binding site [chemical binding]; other site
1267753004509	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
1267753004510	Iron-sulfur protein interface; other site
1267753004511	proximal quinone binding site [chemical binding]; other site
1267753004512	SdhD (CybS) interface [polypeptide binding]; other site
1267753004513	proximal heme binding site [chemical binding]; other site
1267753004514	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1267753004515	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1267753004516	dimer interface [polypeptide binding]; other site
1267753004517	active site
1267753004518	citrylCoA binding site [chemical binding]; other site
1267753004519	NADH binding [chemical binding]; other site
1267753004520	cationic pore residues; other site
1267753004521	oxalacetate/citrate binding site [chemical binding]; other site
1267753004522	coenzyme A binding site [chemical binding]; other site
1267753004523	catalytic triad [active]
1267753004524	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
1267753004525	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1267753004526	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
1267753004527	endonuclease VIII; Provisional; Region: PRK10445
1267753004528	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
1267753004529	DNA binding site [nucleotide binding]
1267753004530	catalytic residue [active]
1267753004531	putative catalytic residues [active]
1267753004532	H2TH interface [polypeptide binding]; other site
1267753004533	intercalation triad [nucleotide binding]; other site
1267753004534	substrate specificity determining residue; other site
1267753004535	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1267753004536	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1267753004537	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1267753004538	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
1267753004539	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1267753004540	active site
1267753004541	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1267753004542	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1267753004543	active site
1267753004544	potential frameshift: common BLAST hit: gi|409249163|ref|YP_006884998.1| Spermidine/putrescine import ATP-binding protein potA
1267753004545	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1267753004546	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1267753004547	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1267753004548	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1267753004549	putative ADP-binding pocket [chemical binding]; other site
1267753004550	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1267753004551	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1267753004552	active site
1267753004553	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
1267753004554	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1267753004555	UDP-galactopyranose mutase; Region: GLF; pfam03275
1267753004556	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753004557	active site
1267753004558	DNA binding site [nucleotide binding]
1267753004559	Int/Topo IB signature motif; other site
1267753004560	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
1267753004561	putative active site [active]
1267753004562	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1267753004563	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1267753004564	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
1267753004565	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1267753004566	metal-binding protein; Provisional; Region: PRK10799
1267753004567	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1267753004568	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753004569	putative substrate translocation pore; other site
1267753004570	POT family; Region: PTR2; pfam00854
1267753004571	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
1267753004572	DNA photolyase; Region: DNA_photolyase; pfam00875
1267753004573	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
1267753004574	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1267753004575	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1267753004576	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1267753004577	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
1267753004578	sensor protein KdpD; Provisional; Region: PRK10490
1267753004579	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1267753004580	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1267753004581	Ligand Binding Site [chemical binding]; other site
1267753004582	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1267753004583	GAF domain; Region: GAF_3; pfam13492
1267753004584	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753004585	dimer interface [polypeptide binding]; other site
1267753004586	phosphorylation site [posttranslational modification]
1267753004587	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753004588	ATP binding site [chemical binding]; other site
1267753004589	Mg2+ binding site [ion binding]; other site
1267753004590	G-X-G motif; other site
1267753004591	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
1267753004592	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753004593	active site
1267753004594	phosphorylation site [posttranslational modification]
1267753004595	intermolecular recognition site; other site
1267753004596	dimerization interface [polypeptide binding]; other site
1267753004597	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753004598	DNA binding site [nucleotide binding]
1267753004599	ornithine decarboxylase; Provisional; Region: PRK13578
1267753004600	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1267753004601	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1267753004602	homodimer interface [polypeptide binding]; other site
1267753004603	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753004604	catalytic residue [active]
1267753004605	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1267753004606	putrescine transporter; Provisional; Region: potE; PRK10655
1267753004607	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
1267753004608	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
1267753004609	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
1267753004610	active site
1267753004611	substrate binding site [chemical binding]; other site
1267753004612	metal binding site [ion binding]; metal-binding site
1267753004613	replication initiation regulator SeqA; Provisional; Region: PRK11187
1267753004614	acyl-CoA esterase; Provisional; Region: PRK10673
1267753004615	PGAP1-like protein; Region: PGAP1; pfam07819
1267753004616	LexA regulated protein; Provisional; Region: PRK11675
1267753004617	flavodoxin FldA; Validated; Region: PRK09267
1267753004618	ferric uptake regulator; Provisional; Region: fur; PRK09462
1267753004619	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1267753004620	metal binding site 2 [ion binding]; metal-binding site
1267753004621	putative DNA binding helix; other site
1267753004622	metal binding site 1 [ion binding]; metal-binding site
1267753004623	dimer interface [polypeptide binding]; other site
1267753004624	structural Zn2+ binding site [ion binding]; other site
1267753004625	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753004626	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753004627	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
1267753004628	putative dimerization interface [polypeptide binding]; other site
1267753004629	tricarballylate dehydrogenase; Validated; Region: PRK08274
1267753004630	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1267753004631	tricarballylate utilization protein B; Provisional; Region: PRK15033
1267753004632	citrate-proton symporter; Provisional; Region: PRK15075
1267753004633	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753004634	putative substrate translocation pore; other site
1267753004635	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1267753004636	YbfN-like lipoprotein; Region: YbfN; pfam13982
1267753004637	outer membrane porin, OprD family; Region: OprD; pfam03573
1267753004638	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1267753004639	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1267753004640	active site
1267753004641	HIGH motif; other site
1267753004642	nucleotide binding site [chemical binding]; other site
1267753004643	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1267753004644	KMSKS motif; other site
1267753004645	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1267753004646	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
1267753004647	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1267753004648	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1267753004649	active site turn [active]
1267753004650	phosphorylation site [posttranslational modification]
1267753004651	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1267753004652	HPr interaction site; other site
1267753004653	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1267753004654	active site
1267753004655	phosphorylation site [posttranslational modification]
1267753004656	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1267753004657	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1267753004658	active site
1267753004659	trimer interface [polypeptide binding]; other site
1267753004660	allosteric site; other site
1267753004661	active site lid [active]
1267753004662	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1267753004663	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
1267753004664	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1267753004665	active site
1267753004666	dimer interface [polypeptide binding]; other site
1267753004667	MarR family; Region: MarR; pfam01047
1267753004668	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1267753004669	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1267753004670	nucleotide binding site [chemical binding]; other site
1267753004671	UMP phosphatase; Provisional; Region: PRK10444
1267753004672	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753004673	active site
1267753004674	motif I; other site
1267753004675	motif II; other site
1267753004676	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753004677	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1267753004678	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1267753004679	active site
1267753004680	dimer interface [polypeptide binding]; other site
1267753004681	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1267753004682	Ligand Binding Site [chemical binding]; other site
1267753004683	Molecular Tunnel; other site
1267753004684	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
1267753004685	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1267753004686	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
1267753004687	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1267753004688	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753004689	FeS/SAM binding site; other site
1267753004690	TRAM domain; Region: TRAM; pfam01938
1267753004691	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1267753004692	PhoH-like protein; Region: PhoH; pfam02562
1267753004693	metal-binding heat shock protein; Provisional; Region: PRK00016
1267753004694	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
1267753004695	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1267753004696	Transporter associated domain; Region: CorC_HlyC; smart01091
1267753004697	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
1267753004698	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
1267753004699	putative active site [active]
1267753004700	catalytic triad [active]
1267753004701	putative dimer interface [polypeptide binding]; other site
1267753004702	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
1267753004703	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753004704	substrate binding pocket [chemical binding]; other site
1267753004705	membrane-bound complex binding site; other site
1267753004706	hinge residues; other site
1267753004707	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1267753004708	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753004709	dimer interface [polypeptide binding]; other site
1267753004710	conserved gate region; other site
1267753004711	putative PBP binding loops; other site
1267753004712	ABC-ATPase subunit interface; other site
1267753004713	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1267753004714	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753004715	dimer interface [polypeptide binding]; other site
1267753004716	conserved gate region; other site
1267753004717	putative PBP binding loops; other site
1267753004718	ABC-ATPase subunit interface; other site
1267753004719	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1267753004720	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1267753004721	Walker A/P-loop; other site
1267753004722	ATP binding site [chemical binding]; other site
1267753004723	Q-loop/lid; other site
1267753004724	ABC transporter signature motif; other site
1267753004725	Walker B; other site
1267753004726	D-loop; other site
1267753004727	H-loop/switch region; other site
1267753004728	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1267753004729	active site
1267753004730	tetramer interface [polypeptide binding]; other site
1267753004731	hypothetical protein; Provisional; Region: PRK11032
1267753004732	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1267753004733	potential frameshift: common BLAST hit: gi|409249095|ref|YP_006884932.1| putative sigma L-dependent transcriptional regulator yqiR
1267753004734	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
1267753004735	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1267753004736	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1267753004737	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1267753004738	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1267753004739	HIGH motif; other site
1267753004740	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1267753004741	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1267753004742	active site
1267753004743	KMSKS motif; other site
1267753004744	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1267753004745	tRNA binding surface [nucleotide binding]; other site
1267753004746	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
1267753004747	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1267753004748	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1267753004749	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1267753004750	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1267753004751	active site
1267753004752	(T/H)XGH motif; other site
1267753004753	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
1267753004754	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753004755	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753004756	homodimer interface [polypeptide binding]; other site
1267753004757	catalytic residue [active]
1267753004758	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1267753004759	catalytic core [active]
1267753004760	ribosome-associated protein; Provisional; Region: PRK11538
1267753004761	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
1267753004762	penicillin-binding protein 2; Provisional; Region: PRK10795
1267753004763	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1267753004764	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1267753004765	cell wall shape-determining protein; Provisional; Region: PRK10794
1267753004766	rare lipoprotein A; Provisional; Region: PRK10672
1267753004767	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1267753004768	Sporulation related domain; Region: SPOR; pfam05036
1267753004769	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
1267753004770	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1267753004771	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1267753004772	hypothetical protein; Provisional; Region: PRK04998
1267753004773	lipoate-protein ligase B; Provisional; Region: PRK14342
1267753004774	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1267753004775	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753004776	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1267753004777	substrate binding pocket [chemical binding]; other site
1267753004778	dimerization interface [polypeptide binding]; other site
1267753004779	lipoyl synthase; Provisional; Region: PRK05481
1267753004780	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753004781	FeS/SAM binding site; other site
1267753004782	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
1267753004783	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1267753004784	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
1267753004785	putative active site [active]
1267753004786	catalytic triad [active]
1267753004787	putative dimer interface [polypeptide binding]; other site
1267753004788	chromosome condensation membrane protein; Provisional; Region: PRK14196
1267753004789	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1267753004790	DNA-binding site [nucleotide binding]; DNA binding site
1267753004791	RNA-binding motif; other site
1267753004792	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
1267753004793	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
1267753004794	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1267753004795	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
1267753004796	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753004797	active site
1267753004798	phosphorylation site [posttranslational modification]
1267753004799	intermolecular recognition site; other site
1267753004800	dimerization interface [polypeptide binding]; other site
1267753004801	Transcriptional regulator; Region: CitT; pfam12431
1267753004802	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
1267753004803	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1267753004804	putative active site [active]
1267753004805	heme pocket [chemical binding]; other site
1267753004806	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753004807	Mg2+ binding site [ion binding]; other site
1267753004808	G-X-G motif; other site
1267753004809	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1267753004810	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1267753004811	putative active site [active]
1267753004812	(T/H)XGH motif; other site
1267753004813	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1267753004814	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1267753004815	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1267753004816	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1267753004817	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1267753004818	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
1267753004819	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1267753004820	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1267753004821	transmembrane helices; other site
1267753004822	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
1267753004823	B1 nucleotide binding pocket [chemical binding]; other site
1267753004824	B2 nucleotide binding pocket [chemical binding]; other site
1267753004825	CAS motifs; other site
1267753004826	active site
1267753004827	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
1267753004828	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1267753004829	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1267753004830	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1267753004831	NAD binding site [chemical binding]; other site
1267753004832	catalytic Zn binding site [ion binding]; other site
1267753004833	structural Zn binding site [ion binding]; other site
1267753004834	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1267753004835	Ligand Binding Site [chemical binding]; other site
1267753004836	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1267753004837	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1267753004838	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1267753004839	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1267753004840	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
1267753004841	putative [4Fe-4S] binding site [ion binding]; other site
1267753004842	putative molybdopterin cofactor binding site [chemical binding]; other site
1267753004843	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
1267753004844	molybdopterin cofactor binding site; other site
1267753004845	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1267753004846	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1267753004847	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1267753004848	catalytic residue [active]
1267753004849	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1267753004850	catalytic residues [active]
1267753004851	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1267753004852	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753004853	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
1267753004854	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1267753004855	dimer interface [polypeptide binding]; other site
1267753004856	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1267753004857	catalytic triad [active]
1267753004858	peroxidatic and resolving cysteines [active]
1267753004859	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
1267753004860	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1267753004861	dimerization domain [polypeptide binding]; other site
1267753004862	dimer interface [polypeptide binding]; other site
1267753004863	catalytic residues [active]
1267753004864	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
1267753004865	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753004866	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1267753004867	dimerization interface [polypeptide binding]; other site
1267753004868	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
1267753004869	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1267753004870	Active Sites [active]
1267753004871	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
1267753004872	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1267753004873	ParB-like nuclease domain; Region: ParBc; pfam02195
1267753004874	methionine aminotransferase; Validated; Region: PRK09082
1267753004875	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753004876	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753004877	homodimer interface [polypeptide binding]; other site
1267753004878	catalytic residue [active]
1267753004879	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1267753004880	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1267753004881	putative active site [active]
1267753004882	metal binding site [ion binding]; metal-binding site
1267753004883	Uncharacterized small protein [Function unknown]; Region: COG2879
1267753004884	carbon starvation protein A; Provisional; Region: PRK15015
1267753004885	Carbon starvation protein CstA; Region: CstA; pfam02554
1267753004886	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1267753004887	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1267753004888	CoenzymeA binding site [chemical binding]; other site
1267753004889	subunit interaction site [polypeptide binding]; other site
1267753004890	PHB binding site; other site
1267753004891	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
1267753004892	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
1267753004893	putative NAD(P) binding site [chemical binding]; other site
1267753004894	active site
1267753004895	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
1267753004896	hydrophobic substrate binding pocket; other site
1267753004897	Isochorismatase family; Region: Isochorismatase; pfam00857
1267753004898	active site
1267753004899	conserved cis-peptide bond; other site
1267753004900	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
1267753004901	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
1267753004902	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
1267753004903	acyl-activating enzyme (AAE) consensus motif; other site
1267753004904	active site
1267753004905	AMP binding site [chemical binding]; other site
1267753004906	substrate binding site [chemical binding]; other site
1267753004907	isochorismate synthase EntC; Provisional; Region: PRK15016
1267753004908	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1267753004909	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
1267753004910	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1267753004911	siderophore binding site; other site
1267753004912	enterobactin exporter EntS; Provisional; Region: PRK10489
1267753004913	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753004914	putative substrate translocation pore; other site
1267753004915	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1267753004916	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1267753004917	ABC-ATPase subunit  interface; other site
1267753004918	dimer interface [polypeptide binding]; other site
1267753004919	putative PBP binding regions; other site
1267753004920	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1267753004921	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1267753004922	ABC-ATPase subunit  interface; other site
1267753004923	dimer interface [polypeptide binding]; other site
1267753004924	putative PBP binding regions; other site
1267753004925	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
1267753004926	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1267753004927	Walker A/P-loop; other site
1267753004928	ATP binding site [chemical binding]; other site
1267753004929	Q-loop/lid; other site
1267753004930	ABC transporter signature motif; other site
1267753004931	Walker B; other site
1267753004932	D-loop; other site
1267753004933	H-loop/switch region; other site
1267753004934	LPS O-antigen length regulator; Provisional; Region: PRK10381
1267753004935	Chain length determinant protein; Region: Wzz; pfam02706
1267753004936	potential frameshift: common BLAST hit: gi|386590518|ref|YP_006086918.1| Enterobactin synthetase component F
1267753004937	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
1267753004938	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
1267753004939	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1267753004940	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1267753004941	outer membrane receptor FepA; Provisional; Region: PRK13524
1267753004942	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1267753004943	N-terminal plug; other site
1267753004944	ligand-binding site [chemical binding]; other site
1267753004945	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
1267753004946	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1267753004947	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
1267753004948	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
1267753004949	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
1267753004950	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1267753004951	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753004952	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1267753004953	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753004954	hypothetical protein; Provisional; Region: PRK10250
1267753004955	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1267753004956	dimer interface [polypeptide binding]; other site
1267753004957	FMN binding site [chemical binding]; other site
1267753004958	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
1267753004959	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1267753004960	active site
1267753004961	oxyanion hole [active]
1267753004962	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1267753004963	catalytic triad [active]
1267753004964	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1267753004965	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1267753004966	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1267753004967	phenylalanine transporter; Provisional; Region: PRK10249
1267753004968	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
1267753004969	Predicted membrane protein [Function unknown]; Region: COG3059
1267753004970	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753004971	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
1267753004972	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753004973	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1267753004974	Cupin; Region: Cupin_6; pfam12852
1267753004975	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1267753004976	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753004977	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753004978	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
1267753004979	Predicted membrane protein [Function unknown]; Region: COG2246
1267753004980	GtrA-like protein; Region: GtrA; pfam04138
1267753004981	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1267753004982	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1267753004983	Ligand binding site; other site
1267753004984	Putative Catalytic site; other site
1267753004985	DXD motif; other site
1267753004986	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1267753004987	Transposase; Region: HTH_Tnp_1; pfam01527
1267753004988	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
1267753004989	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753004990	DNA binding residues [nucleotide binding]
1267753004991	dimerization interface [polypeptide binding]; other site
1267753004992	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
1267753004993	transcriptional regulator FimZ; Provisional; Region: PRK09935
1267753004994	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753004995	active site
1267753004996	phosphorylation site [posttranslational modification]
1267753004997	intermolecular recognition site; other site
1267753004998	dimerization interface [polypeptide binding]; other site
1267753004999	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753005000	DNA binding residues [nucleotide binding]
1267753005001	dimerization interface [polypeptide binding]; other site
1267753005002	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
1267753005003	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
1267753005004	outer membrane usher protein FimD; Provisional; Region: PRK15198
1267753005005	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753005006	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753005007	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753005008	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
1267753005009	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753005010	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753005011	fimbrial protein FimI; Provisional; Region: PRK15200
1267753005012	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
1267753005013	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
1267753005014	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1267753005015	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1267753005016	homodimer interface [polypeptide binding]; other site
1267753005017	NADP binding site [chemical binding]; other site
1267753005018	substrate binding site [chemical binding]; other site
1267753005019	ribosome-associated protein; Provisional; Region: PRK11507
1267753005020	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
1267753005021	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
1267753005022	Uncharacterized protein conserved in bacteria (DUF2145); Region: DUF2145; pfam09916
1267753005023	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1267753005024	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1267753005025	active site
1267753005026	HIGH motif; other site
1267753005027	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1267753005028	KMSKS motif; other site
1267753005029	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
1267753005030	tRNA binding surface [nucleotide binding]; other site
1267753005031	anticodon binding site; other site
1267753005032	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1267753005033	substrate binding site [chemical binding]; other site
1267753005034	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1267753005035	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1267753005036	putative active site [active]
1267753005037	putative metal binding site [ion binding]; other site
1267753005038	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1267753005039	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1267753005040	ATP-grasp domain; Region: ATP-grasp; pfam02222
1267753005041	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
1267753005042	Predicted ATPase [General function prediction only]; Region: COG2603
1267753005043	active site residue [active]
1267753005044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753005045	dimer interface [polypeptide binding]; other site
1267753005046	conserved gate region; other site
1267753005047	ABC-ATPase subunit interface; other site
1267753005048	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1267753005049	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1267753005050	Walker A/P-loop; other site
1267753005051	ATP binding site [chemical binding]; other site
1267753005052	Q-loop/lid; other site
1267753005053	ABC transporter signature motif; other site
1267753005054	Walker B; other site
1267753005055	D-loop; other site
1267753005056	H-loop/switch region; other site
1267753005057	NIL domain; Region: NIL; pfam09383
1267753005058	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1267753005059	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1267753005060	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1267753005061	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1267753005062	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
1267753005063	FtsX-like permease family; Region: FtsX; pfam02687
1267753005064	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
1267753005065	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1267753005066	Walker A/P-loop; other site
1267753005067	ATP binding site [chemical binding]; other site
1267753005068	Q-loop/lid; other site
1267753005069	ABC transporter signature motif; other site
1267753005070	Walker B; other site
1267753005071	D-loop; other site
1267753005072	H-loop/switch region; other site
1267753005073	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
1267753005074	active site
1267753005075	catalytic triad [active]
1267753005076	oxyanion hole [active]
1267753005077	switch loop; other site
1267753005078	oxidoreductase; Provisional; Region: PRK08017
1267753005079	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1267753005080	NADP binding site [chemical binding]; other site
1267753005081	active site
1267753005082	steroid binding site; other site
1267753005083	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
1267753005084	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
1267753005085	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
1267753005086	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
1267753005087	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1267753005088	Walker A/P-loop; other site
1267753005089	ATP binding site [chemical binding]; other site
1267753005090	Q-loop/lid; other site
1267753005091	ABC transporter signature motif; other site
1267753005092	Walker B; other site
1267753005093	D-loop; other site
1267753005094	H-loop/switch region; other site
1267753005095	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1267753005096	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1267753005097	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1267753005098	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
1267753005099	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1267753005100	DNA binding residues [nucleotide binding]
1267753005101	dimer interface [polypeptide binding]; other site
1267753005102	copper binding site [ion binding]; other site
1267753005103	copper exporting ATPase; Provisional; Region: copA; PRK10671
1267753005104	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1267753005105	metal-binding site [ion binding]
1267753005106	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1267753005107	metal-binding site [ion binding]
1267753005108	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1267753005109	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753005110	motif II; other site
1267753005111	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
1267753005112	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1267753005113	putative deacylase active site [active]
1267753005114	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1267753005115	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
1267753005116	active site
1267753005117	metal binding site [ion binding]; metal-binding site
1267753005118	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1267753005119	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753005120	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1267753005121	putative substrate translocation pore; other site
1267753005122	putative cation:proton antiport protein; Provisional; Region: PRK10669
1267753005123	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
1267753005124	TrkA-N domain; Region: TrkA_N; pfam02254
1267753005125	inosine/guanosine kinase; Provisional; Region: PRK15074
1267753005126	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753005127	acetyl esterase; Provisional; Region: PRK10162
1267753005128	ferrochelatase; Reviewed; Region: hemH; PRK00035
1267753005129	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1267753005130	C-terminal domain interface [polypeptide binding]; other site
1267753005131	active site
1267753005132	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1267753005133	active site
1267753005134	N-terminal domain interface [polypeptide binding]; other site
1267753005135	adenylate kinase; Reviewed; Region: adk; PRK00279
1267753005136	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1267753005137	AMP-binding site [chemical binding]; other site
1267753005138	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1267753005139	heat shock protein 90; Provisional; Region: PRK05218
1267753005140	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753005141	ATP binding site [chemical binding]; other site
1267753005142	Mg2+ binding site [ion binding]; other site
1267753005143	G-X-G motif; other site
1267753005144	recombination protein RecR; Reviewed; Region: recR; PRK00076
1267753005145	RecR protein; Region: RecR; pfam02132
1267753005146	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1267753005147	putative active site [active]
1267753005148	putative metal-binding site [ion binding]; other site
1267753005149	tetramer interface [polypeptide binding]; other site
1267753005150	hypothetical protein; Validated; Region: PRK00153
1267753005151	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
1267753005152	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753005153	Walker A motif; other site
1267753005154	ATP binding site [chemical binding]; other site
1267753005155	Walker B motif; other site
1267753005156	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1267753005157	arginine finger; other site
1267753005158	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1267753005159	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
1267753005160	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
1267753005161	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1267753005162	active site
1267753005163	hypothetical protein; Provisional; Region: PRK10527
1267753005164	primosomal replication protein N''; Provisional; Region: PRK10093
1267753005165	hypothetical protein; Provisional; Region: PRK11038
1267753005166	Uncharacterized conserved protein [Function unknown]; Region: COG5464
1267753005167	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1267753005168	hypothetical protein; Provisional; Region: PRK11281
1267753005169	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1267753005170	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1267753005171	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
1267753005172	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753005173	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1267753005174	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1267753005175	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753005176	potential frameshift: common BLAST hit: gi|409248921|ref|YP_006884758.1| Toluene efflux pump membrane transporter ttgB
1267753005177	Hha toxicity attenuator; Provisional; Region: PRK10667
1267753005178	gene expression modulator; Provisional; Region: PRK10945
1267753005179	maltose O-acetyltransferase; Provisional; Region: PRK10092
1267753005180	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1267753005181	active site
1267753005182	substrate binding site [chemical binding]; other site
1267753005183	trimer interface [polypeptide binding]; other site
1267753005184	CoA binding site [chemical binding]; other site
1267753005185	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
1267753005186	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
1267753005187	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1267753005188	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1267753005189	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1267753005190	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753005191	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1267753005192	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1267753005193	DNA binding site [nucleotide binding]
1267753005194	active site
1267753005195	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
1267753005196	acyl-CoA thioesterase II; Provisional; Region: PRK10526
1267753005197	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
1267753005198	active site
1267753005199	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
1267753005200	catalytic triad [active]
1267753005201	dimer interface [polypeptide binding]; other site
1267753005202	ammonium transporter; Provisional; Region: PRK10666
1267753005203	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
1267753005204	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1267753005205	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
1267753005206	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1267753005207	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753005208	Walker A/P-loop; other site
1267753005209	ATP binding site [chemical binding]; other site
1267753005210	Q-loop/lid; other site
1267753005211	ABC transporter signature motif; other site
1267753005212	Walker B; other site
1267753005213	D-loop; other site
1267753005214	H-loop/switch region; other site
1267753005215	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1267753005216	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1267753005217	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753005218	Walker A/P-loop; other site
1267753005219	ATP binding site [chemical binding]; other site
1267753005220	Q-loop/lid; other site
1267753005221	ABC transporter signature motif; other site
1267753005222	Walker B; other site
1267753005223	D-loop; other site
1267753005224	H-loop/switch region; other site
1267753005225	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1267753005226	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1267753005227	putative DNA binding site [nucleotide binding]; other site
1267753005228	putative Zn2+ binding site [ion binding]; other site
1267753005229	AsnC family; Region: AsnC_trans_reg; pfam01037
1267753005230	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1267753005231	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1267753005232	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1267753005233	catalytic residue [active]
1267753005234	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
1267753005235	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753005236	active site
1267753005237	motif I; other site
1267753005238	motif II; other site
1267753005239	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1267753005240	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1267753005241	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1267753005242	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1267753005243	Ligand Binding Site [chemical binding]; other site
1267753005244	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1267753005245	active site
1267753005246	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
1267753005247	periplasmic folding chaperone; Provisional; Region: PRK10788
1267753005248	SurA N-terminal domain; Region: SurA_N_3; cl07813
1267753005249	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1267753005250	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1267753005251	IHF dimer interface [polypeptide binding]; other site
1267753005252	IHF - DNA interface [nucleotide binding]; other site
1267753005253	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
1267753005254	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1267753005255	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1267753005256	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753005257	Walker A motif; other site
1267753005258	ATP binding site [chemical binding]; other site
1267753005259	Walker B motif; other site
1267753005260	arginine finger; other site
1267753005261	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1267753005262	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1267753005263	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1267753005264	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753005265	Walker A motif; other site
1267753005266	ATP binding site [chemical binding]; other site
1267753005267	Walker B motif; other site
1267753005268	Iron permease FTR1 family; Region: FTR1; cl00475
1267753005269	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1267753005270	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1267753005271	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1267753005272	oligomer interface [polypeptide binding]; other site
1267753005273	active site residues [active]
1267753005274	trigger factor; Provisional; Region: tig; PRK01490
1267753005275	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1267753005276	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1267753005277	transcriptional regulator BolA; Provisional; Region: PRK11628
1267753005278	hypothetical protein; Provisional; Region: PRK11627
1267753005279	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
1267753005280	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
1267753005281	muropeptide transporter; Reviewed; Region: ampG; PRK11902
1267753005282	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753005283	putative substrate translocation pore; other site
1267753005284	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
1267753005285	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1267753005286	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
1267753005287	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1267753005288	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1267753005289	D-pathway; other site
1267753005290	Putative ubiquinol binding site [chemical binding]; other site
1267753005291	Low-spin heme (heme b) binding site [chemical binding]; other site
1267753005292	Putative water exit pathway; other site
1267753005293	Binuclear center (heme o3/CuB) [ion binding]; other site
1267753005294	K-pathway; other site
1267753005295	Putative proton exit pathway; other site
1267753005296	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1267753005297	Subunit I/III interface [polypeptide binding]; other site
1267753005298	Subunit III/IV interface [polypeptide binding]; other site
1267753005299	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
1267753005300	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
1267753005301	UbiA prenyltransferase family; Region: UbiA; pfam01040
1267753005302	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753005303	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1267753005304	putative substrate translocation pore; other site
1267753005305	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1267753005306	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1267753005307	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1267753005308	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1267753005309	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1267753005310	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
1267753005311	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1267753005312	conserved cys residue [active]
1267753005313	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
1267753005314	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753005315	motif II; other site
1267753005316	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1267753005317	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
1267753005318	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1267753005319	catalytic residue [active]
1267753005320	transcriptional regulator protein; Region: phnR; TIGR03337
1267753005321	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753005322	DNA-binding site [nucleotide binding]; DNA binding site
1267753005323	UTRA domain; Region: UTRA; pfam07702
1267753005324	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
1267753005325	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1267753005326	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
1267753005327	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753005328	Walker A/P-loop; other site
1267753005329	ATP binding site [chemical binding]; other site
1267753005330	Q-loop/lid; other site
1267753005331	ABC transporter signature motif; other site
1267753005332	Walker B; other site
1267753005333	D-loop; other site
1267753005334	H-loop/switch region; other site
1267753005335	TOBE domain; Region: TOBE_2; pfam08402
1267753005336	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
1267753005337	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753005338	dimer interface [polypeptide binding]; other site
1267753005339	conserved gate region; other site
1267753005340	putative PBP binding loops; other site
1267753005341	ABC-ATPase subunit interface; other site
1267753005342	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1267753005343	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753005344	dimer interface [polypeptide binding]; other site
1267753005345	conserved gate region; other site
1267753005346	ABC-ATPase subunit interface; other site
1267753005347	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
1267753005348	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1267753005349	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1267753005350	Ligand Binding Site [chemical binding]; other site
1267753005351	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1267753005352	active site residue [active]
1267753005353	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1267753005354	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1267753005355	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1267753005356	substrate binding pocket [chemical binding]; other site
1267753005357	chain length determination region; other site
1267753005358	substrate-Mg2+ binding site; other site
1267753005359	catalytic residues [active]
1267753005360	aspartate-rich region 1; other site
1267753005361	active site lid residues [active]
1267753005362	aspartate-rich region 2; other site
1267753005363	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
1267753005364	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1267753005365	TPP-binding site; other site
1267753005366	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1267753005367	PYR/PP interface [polypeptide binding]; other site
1267753005368	dimer interface [polypeptide binding]; other site
1267753005369	TPP binding site [chemical binding]; other site
1267753005370	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1267753005371	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1267753005372	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1267753005373	active site
1267753005374	catalytic tetrad [active]
1267753005375	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1267753005376	tetramer interfaces [polypeptide binding]; other site
1267753005377	binuclear metal-binding site [ion binding]; other site
1267753005378	thiamine monophosphate kinase; Provisional; Region: PRK05731
1267753005379	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1267753005380	ATP binding site [chemical binding]; other site
1267753005381	dimerization interface [polypeptide binding]; other site
1267753005382	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1267753005383	putative RNA binding site [nucleotide binding]; other site
1267753005384	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1267753005385	homopentamer interface [polypeptide binding]; other site
1267753005386	active site
1267753005387	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
1267753005388	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1267753005389	catalytic motif [active]
1267753005390	Zn binding site [ion binding]; other site
1267753005391	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
1267753005392	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1267753005393	ATP cone domain; Region: ATP-cone; pfam03477
1267753005394	hypothetical protein; Provisional; Region: PRK11530
1267753005395	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
1267753005396	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1267753005397	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1267753005398	active site
1267753005399	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1267753005400	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1267753005401	Protein export membrane protein; Region: SecD_SecF; pfam02355
1267753005402	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
1267753005403	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1267753005404	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1267753005405	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1267753005406	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1267753005407	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1267753005408	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
1267753005409	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1267753005410	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1267753005411	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
1267753005412	peroxidase; Provisional; Region: PRK15000
1267753005413	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1267753005414	dimer interface [polypeptide binding]; other site
1267753005415	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1267753005416	catalytic triad [active]
1267753005417	peroxidatic and resolving cysteines [active]
1267753005418	maltodextrin glucosidase; Provisional; Region: PRK10785
1267753005419	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1267753005420	homodimer interface [polypeptide binding]; other site
1267753005421	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1267753005422	active site
1267753005423	homodimer interface [polypeptide binding]; other site
1267753005424	catalytic site [active]
1267753005425	putative proline-specific permease; Provisional; Region: proY; PRK10580
1267753005426	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
1267753005427	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
1267753005428	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
1267753005429	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1267753005430	putative active site [active]
1267753005431	heme pocket [chemical binding]; other site
1267753005432	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753005433	dimer interface [polypeptide binding]; other site
1267753005434	phosphorylation site [posttranslational modification]
1267753005435	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753005436	ATP binding site [chemical binding]; other site
1267753005437	Mg2+ binding site [ion binding]; other site
1267753005438	G-X-G motif; other site
1267753005439	transcriptional regulator PhoB; Provisional; Region: PRK10161
1267753005440	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753005441	active site
1267753005442	phosphorylation site [posttranslational modification]
1267753005443	intermolecular recognition site; other site
1267753005444	dimerization interface [polypeptide binding]; other site
1267753005445	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753005446	DNA binding site [nucleotide binding]
1267753005447	exonuclease subunit SbcD; Provisional; Region: PRK10966
1267753005448	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1267753005449	active site
1267753005450	metal binding site [ion binding]; metal-binding site
1267753005451	DNA binding site [nucleotide binding]
1267753005452	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1267753005453	exonuclease subunit SbcC; Provisional; Region: PRK10246
1267753005454	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753005455	Walker A/P-loop; other site
1267753005456	ATP binding site [chemical binding]; other site
1267753005457	Q-loop/lid; other site
1267753005458	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753005459	ABC transporter signature motif; other site
1267753005460	Walker B; other site
1267753005461	D-loop; other site
1267753005462	H-loop/switch region; other site
1267753005463	MFS transport protein AraJ; Provisional; Region: PRK10091
1267753005464	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753005465	putative substrate translocation pore; other site
1267753005466	fructokinase; Reviewed; Region: PRK09557
1267753005467	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1267753005468	nucleotide binding site [chemical binding]; other site
1267753005469	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
1267753005470	hypothetical protein; Provisional; Region: PRK10579
1267753005471	hypothetical protein; Provisional; Region: PRK10481
1267753005472	hypothetical protein; Provisional; Region: PRK10380
1267753005473	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1267753005474	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1267753005475	ADP binding site [chemical binding]; other site
1267753005476	magnesium binding site [ion binding]; other site
1267753005477	putative shikimate binding site; other site
1267753005478	hypothetical protein; Validated; Region: PRK00124
1267753005479	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1267753005480	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1267753005481	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
1267753005482	MASE2 domain; Region: MASE2; pfam05230
1267753005483	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753005484	metal binding site [ion binding]; metal-binding site
1267753005485	active site
1267753005486	I-site; other site
1267753005487	hypothetical protein; Provisional; Region: PRK11505
1267753005488	psiF repeat; Region: PsiF_repeat; pfam07769
1267753005489	psiF repeat; Region: PsiF_repeat; pfam07769
1267753005490	anti-RssB factor; Provisional; Region: PRK10244
1267753005491	drug efflux system protein MdtG; Provisional; Region: PRK09874
1267753005492	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753005493	putative substrate translocation pore; other site
1267753005494	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
1267753005495	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
1267753005496	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1267753005497	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1267753005498	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1267753005499	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
1267753005500	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
1267753005501	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
1267753005502	microcin B17 transporter; Reviewed; Region: PRK11098
1267753005503	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
1267753005504	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1267753005505	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1267753005506	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1267753005507	ligand binding site [chemical binding]; other site
1267753005508	flexible hinge region; other site
1267753005509	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
1267753005510	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1267753005511	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1267753005512	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1267753005513	dimer interface [polypeptide binding]; other site
1267753005514	active site
1267753005515	Schiff base residues; other site
1267753005516	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1267753005517	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1267753005518	acyl-activating enzyme (AAE) consensus motif; other site
1267753005519	AMP binding site [chemical binding]; other site
1267753005520	active site
1267753005521	CoA binding site [chemical binding]; other site
1267753005522	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
1267753005523	2-methylcitrate dehydratase; Region: prpD; TIGR02330
1267753005524	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1267753005525	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
1267753005526	dimer interface [polypeptide binding]; other site
1267753005527	active site
1267753005528	citrylCoA binding site [chemical binding]; other site
1267753005529	oxalacetate/citrate binding site [chemical binding]; other site
1267753005530	coenzyme A binding site [chemical binding]; other site
1267753005531	catalytic triad [active]
1267753005532	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1267753005533	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
1267753005534	tetramer interface [polypeptide binding]; other site
1267753005535	active site
1267753005536	Mg2+/Mn2+ binding site [ion binding]; other site
1267753005537	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
1267753005538	Propionate catabolism activator; Region: PrpR_N; pfam06506
1267753005539	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753005540	Walker A motif; other site
1267753005541	ATP binding site [chemical binding]; other site
1267753005542	Walker B motif; other site
1267753005543	arginine finger; other site
1267753005544	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1267753005545	hypothetical protein; Provisional; Region: PRK09929
1267753005546	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
1267753005547	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
1267753005548	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1267753005549	N-terminal plug; other site
1267753005550	ligand-binding site [chemical binding]; other site
1267753005551	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1267753005552	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1267753005553	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1267753005554	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1267753005555	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1267753005556	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
1267753005557	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
1267753005558	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1267753005559	VRR-NUC domain; Region: VRR_NUC; pfam08774
1267753005560	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1267753005561	DNA methylase; Region: N6_N4_Mtase; cl17433
1267753005562	DNA methylase; Region: N6_N4_Mtase; pfam01555
1267753005563	putative sialic acid transporter; Region: 2A0112; TIGR00891
1267753005564	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753005565	putative substrate translocation pore; other site
1267753005566	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1267753005567	metal-binding site [ion binding]
1267753005568	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
1267753005569	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
1267753005570	DNA binding residues [nucleotide binding]
1267753005571	dimer interface [polypeptide binding]; other site
1267753005572	copper binding site [ion binding]; other site
1267753005573	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1267753005574	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1267753005575	metal-binding site [ion binding]
1267753005576	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1267753005577	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753005578	motif II; other site
1267753005579	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1267753005580	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753005581	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753005582	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1267753005583	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1267753005584	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1267753005585	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1267753005586	DNA binding residues [nucleotide binding]
1267753005587	dimerization interface [polypeptide binding]; other site
1267753005588	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
1267753005589	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1267753005590	DNA binding site [nucleotide binding]
1267753005591	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1267753005592	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753005593	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
1267753005594	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1267753005595	fimbrial chaperone protein StbB; Provisional; Region: PRK15249
1267753005596	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753005597	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753005598	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
1267753005599	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753005600	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753005601	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753005602	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
1267753005603	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
1267753005604	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753005605	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753005606	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
1267753005607	type III secretion protein SopE; Provisional; Region: PRK15279
1267753005608	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
1267753005609	SopE GEF domain; Region: SopE_GEF; pfam07487
1267753005610	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1267753005611	VRR-NUC domain; Region: VRR_NUC; pfam08774
1267753005612	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
1267753005613	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753005614	nucleotide binding region [chemical binding]; other site
1267753005615	ATP-binding site [chemical binding]; other site
1267753005616	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
1267753005617	integrase; Provisional; Region: PRK09692
1267753005618	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1267753005619	active site
1267753005620	Int/Topo IB signature motif; other site
1267753005621	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1267753005622	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1267753005623	putative catalytic cysteine [active]
1267753005624	gamma-glutamyl kinase; Provisional; Region: PRK05429
1267753005625	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1267753005626	nucleotide binding site [chemical binding]; other site
1267753005627	homotetrameric interface [polypeptide binding]; other site
1267753005628	putative phosphate binding site [ion binding]; other site
1267753005629	putative allosteric binding site; other site
1267753005630	PUA domain; Region: PUA; pfam01472
1267753005631	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1267753005632	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1267753005633	trimer interface [polypeptide binding]; other site
1267753005634	eyelet of channel; other site
1267753005635	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
1267753005636	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
1267753005637	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1267753005638	active site
1267753005639	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1267753005640	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1267753005641	metal binding site [ion binding]; metal-binding site
1267753005642	dimer interface [polypeptide binding]; other site
1267753005643	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1267753005644	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1267753005645	hypothetical protein; Reviewed; Region: PRK09588
1267753005646	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
1267753005647	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1267753005648	active site
1267753005649	DNA polymerase IV; Validated; Region: PRK02406
1267753005650	DNA binding site [nucleotide binding]
1267753005651	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1267753005652	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1267753005653	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
1267753005654	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
1267753005655	putative active site [active]
1267753005656	putative dimer interface [polypeptide binding]; other site
1267753005657	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1267753005658	dimer interface [polypeptide binding]; other site
1267753005659	active site
1267753005660	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
1267753005661	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1267753005662	active site
1267753005663	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
1267753005664	C-N hydrolase family amidase; Provisional; Region: PRK10438
1267753005665	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1267753005666	putative active site [active]
1267753005667	catalytic triad [active]
1267753005668	dimer interface [polypeptide binding]; other site
1267753005669	multimer interface [polypeptide binding]; other site
1267753005670	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1267753005671	dimer interface [polypeptide binding]; other site
1267753005672	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1267753005673	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1267753005674	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
1267753005675	AsnC family; Region: AsnC_trans_reg; pfam01037
1267753005676	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
1267753005677	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
1267753005678	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
1267753005679	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
1267753005680	active site
1267753005681	catalytic site [active]
1267753005682	substrate binding site [chemical binding]; other site
1267753005683	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1267753005684	RNA/DNA hybrid binding site [nucleotide binding]; other site
1267753005685	active site
1267753005686	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753005687	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
1267753005688	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1267753005689	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1267753005690	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1267753005691	catalytic residue [active]
1267753005692	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1267753005693	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1267753005694	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1267753005695	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753005696	S-adenosylmethionine binding site [chemical binding]; other site
1267753005697	hypothetical protein; Provisional; Region: PRK05421
1267753005698	putative catalytic site [active]
1267753005699	putative metal binding site [ion binding]; other site
1267753005700	putative phosphate binding site [ion binding]; other site
1267753005701	putative catalytic site [active]
1267753005702	putative phosphate binding site [ion binding]; other site
1267753005703	putative metal binding site [ion binding]; other site
1267753005704	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1267753005705	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753005706	putative substrate translocation pore; other site
1267753005707	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753005708	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753005709	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
1267753005710	putative effector binding pocket; other site
1267753005711	dimerization interface [polypeptide binding]; other site
1267753005712	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1267753005713	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1267753005714	active site
1267753005715	catalytic tetrad [active]
1267753005716	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
1267753005717	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753005718	active site
1267753005719	motif I; other site
1267753005720	motif II; other site
1267753005721	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1267753005722	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1267753005723	Walker A/P-loop; other site
1267753005724	ATP binding site [chemical binding]; other site
1267753005725	Q-loop/lid; other site
1267753005726	ABC transporter signature motif; other site
1267753005727	Walker B; other site
1267753005728	D-loop; other site
1267753005729	H-loop/switch region; other site
1267753005730	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1267753005731	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753005732	dimer interface [polypeptide binding]; other site
1267753005733	conserved gate region; other site
1267753005734	ABC-ATPase subunit interface; other site
1267753005735	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
1267753005736	lipoprotein, YaeC family; Region: TIGR00363
1267753005737	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
1267753005738	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
1267753005739	homodimer interaction site [polypeptide binding]; other site
1267753005740	cofactor binding site; other site
1267753005741	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1267753005742	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1267753005743	dimer interface [polypeptide binding]; other site
1267753005744	motif 1; other site
1267753005745	active site
1267753005746	motif 2; other site
1267753005747	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1267753005748	putative deacylase active site [active]
1267753005749	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1267753005750	active site
1267753005751	motif 3; other site
1267753005752	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1267753005753	anticodon binding site; other site
1267753005754	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
1267753005755	NlpE N-terminal domain; Region: NlpE; pfam04170
1267753005756	hypothetical protein; Provisional; Region: PRK09256
1267753005757	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1267753005758	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
1267753005759	hypothetical protein; Provisional; Region: PRK04964
1267753005760	Rho-binding antiterminator; Provisional; Region: PRK11625
1267753005761	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
1267753005762	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1267753005763	Ligand Binding Site [chemical binding]; other site
1267753005764	TilS substrate binding domain; Region: TilS; pfam09179
1267753005765	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
1267753005766	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
1267753005767	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1267753005768	putative metal binding site [ion binding]; other site
1267753005769	lysine decarboxylase LdcC; Provisional; Region: PRK15399
1267753005770	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1267753005771	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1267753005772	homodimer interface [polypeptide binding]; other site
1267753005773	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753005774	catalytic residue [active]
1267753005775	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1267753005776	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
1267753005777	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
1267753005778	putative sugar binding site [chemical binding]; other site
1267753005779	catalytic residues [active]
1267753005780	PKD domain; Region: PKD; pfam00801
1267753005781	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1267753005782	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1267753005783	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1267753005784	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
1267753005785	putative active site [active]
1267753005786	putative PHP Thumb interface [polypeptide binding]; other site
1267753005787	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1267753005788	generic binding surface II; other site
1267753005789	generic binding surface I; other site
1267753005790	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1267753005791	RNA/DNA hybrid binding site [nucleotide binding]; other site
1267753005792	active site
1267753005793	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1267753005794	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1267753005795	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1267753005796	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1267753005797	active site
1267753005798	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1267753005799	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1267753005800	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1267753005801	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1267753005802	trimer interface [polypeptide binding]; other site
1267753005803	active site
1267753005804	UDP-GlcNAc binding site [chemical binding]; other site
1267753005805	lipid binding site [chemical binding]; lipid-binding site
1267753005806	periplasmic chaperone; Provisional; Region: PRK10780
1267753005807	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1267753005808	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
1267753005809	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1267753005810	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1267753005811	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1267753005812	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1267753005813	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1267753005814	Surface antigen; Region: Bac_surface_Ag; pfam01103
1267753005815	zinc metallopeptidase RseP; Provisional; Region: PRK10779
1267753005816	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1267753005817	active site
1267753005818	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1267753005819	protein binding site [polypeptide binding]; other site
1267753005820	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1267753005821	protein binding site [polypeptide binding]; other site
1267753005822	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1267753005823	putative substrate binding region [chemical binding]; other site
1267753005824	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1267753005825	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1267753005826	potential frameshift: common BLAST hit: gi|409248647|ref|YP_006884488.1| undecaprenyl pyrophosphate synthetase
1267753005827	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1267753005828	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1267753005829	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1267753005830	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1267753005831	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1267753005832	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1267753005833	hinge region; other site
1267753005834	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1267753005835	putative nucleotide binding site [chemical binding]; other site
1267753005836	uridine monophosphate binding site [chemical binding]; other site
1267753005837	homohexameric interface [polypeptide binding]; other site
1267753005838	elongation factor Ts; Provisional; Region: tsf; PRK09377
1267753005839	UBA/TS-N domain; Region: UBA; pfam00627
1267753005840	Elongation factor TS; Region: EF_TS; pfam00889
1267753005841	Elongation factor TS; Region: EF_TS; pfam00889
1267753005842	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1267753005843	rRNA interaction site [nucleotide binding]; other site
1267753005844	S8 interaction site; other site
1267753005845	putative laminin-1 binding site; other site
1267753005846	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1267753005847	active site
1267753005848	PII uridylyl-transferase; Provisional; Region: PRK05007
1267753005849	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1267753005850	metal binding triad; other site
1267753005851	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1267753005852	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1267753005853	Zn2+ binding site [ion binding]; other site
1267753005854	Mg2+ binding site [ion binding]; other site
1267753005855	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
1267753005856	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
1267753005857	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1267753005858	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1267753005859	trimer interface [polypeptide binding]; other site
1267753005860	active site
1267753005861	substrate binding site [chemical binding]; other site
1267753005862	CoA binding site [chemical binding]; other site
1267753005863	shikimate transporter; Provisional; Region: PRK09952
1267753005864	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753005865	putative substrate translocation pore; other site
1267753005866	hypothetical protein; Provisional; Region: PRK13677
1267753005867	potential frameshift: common BLAST hit: gi|194735270|ref|YP_002113233.1| viral enhancin protein
1267753005868	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
1267753005869	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1267753005870	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1267753005871	serine endoprotease; Provisional; Region: PRK10942
1267753005872	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1267753005873	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1267753005874	protein binding site [polypeptide binding]; other site
1267753005875	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1267753005876	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
1267753005877	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1267753005878	Zn2+ binding site [ion binding]; other site
1267753005879	Mg2+ binding site [ion binding]; other site
1267753005880	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
1267753005881	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1267753005882	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1267753005883	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
1267753005884	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
1267753005885	cobalamin binding residues [chemical binding]; other site
1267753005886	putative BtuC binding residues; other site
1267753005887	dimer interface [polypeptide binding]; other site
1267753005888	hypothetical protein; Provisional; Region: PRK10578
1267753005889	UPF0126 domain; Region: UPF0126; pfam03458
1267753005890	UPF0126 domain; Region: UPF0126; pfam03458
1267753005891	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
1267753005892	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1267753005893	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
1267753005894	Cl- selectivity filter; other site
1267753005895	Cl- binding residues [ion binding]; other site
1267753005896	pore gating glutamate residue; other site
1267753005897	dimer interface [polypeptide binding]; other site
1267753005898	H+/Cl- coupling transport residue; other site
1267753005899	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1267753005900	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1267753005901	inhibitor-cofactor binding pocket; inhibition site
1267753005902	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753005903	catalytic residue [active]
1267753005904	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1267753005905	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1267753005906	ABC-ATPase subunit  interface; other site
1267753005907	dimer interface [polypeptide binding]; other site
1267753005908	putative PBP binding regions; other site
1267753005909	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1267753005910	ABC-ATPase subunit  interface; other site
1267753005911	dimer interface [polypeptide binding]; other site
1267753005912	putative PBP binding regions; other site
1267753005913	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
1267753005914	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1267753005915	siderophore binding site; other site
1267753005916	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
1267753005917	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1267753005918	Walker A/P-loop; other site
1267753005919	ATP binding site [chemical binding]; other site
1267753005920	Q-loop/lid; other site
1267753005921	ABC transporter signature motif; other site
1267753005922	Walker B; other site
1267753005923	D-loop; other site
1267753005924	H-loop/switch region; other site
1267753005925	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1267753005926	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1267753005927	N-terminal plug; other site
1267753005928	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
1267753005929	Transglycosylase; Region: Transgly; pfam00912
1267753005930	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1267753005931	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
1267753005932	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753005933	ATP binding site [chemical binding]; other site
1267753005934	putative Mg++ binding site [ion binding]; other site
1267753005935	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753005936	nucleotide binding region [chemical binding]; other site
1267753005937	ATP-binding site [chemical binding]; other site
1267753005938	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
1267753005939	2'-5' RNA ligase; Provisional; Region: PRK15124
1267753005940	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1267753005941	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1267753005942	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
1267753005943	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
1267753005944	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
1267753005945	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
1267753005946	active site
1267753005947	nucleotide binding site [chemical binding]; other site
1267753005948	HIGH motif; other site
1267753005949	KMSKS motif; other site
1267753005950	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
1267753005951	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1267753005952	active site
1267753005953	NTP binding site [chemical binding]; other site
1267753005954	metal binding triad [ion binding]; metal-binding site
1267753005955	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1267753005956	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
1267753005957	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1267753005958	catalytic center binding site [active]
1267753005959	ATP binding site [chemical binding]; other site
1267753005960	putative fimbrial protein StaA; Provisional; Region: PRK15239
1267753005961	putative chaperone protein EcpD; Provisional; Region: PRK09926
1267753005962	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753005963	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753005964	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
1267753005965	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753005966	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753005967	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753005968	putative fimbrial protein StaD; Provisional; Region: PRK15241
1267753005969	putative fimbrial protein StaE; Provisional; Region: PRK15263
1267753005970	putative fimbrial protein StaF; Provisional; Region: PRK15262
1267753005971	Fimbrial protein; Region: Fimbrial; cl01416
1267753005972	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1267753005973	oligomerization interface [polypeptide binding]; other site
1267753005974	active site
1267753005975	metal binding site [ion binding]; metal-binding site
1267753005976	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1267753005977	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1267753005978	active site
1267753005979	ATP-binding site [chemical binding]; other site
1267753005980	pantoate-binding site; other site
1267753005981	HXXH motif; other site
1267753005982	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1267753005983	tetramerization interface [polypeptide binding]; other site
1267753005984	active site
1267753005985	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
1267753005986	putative active site [active]
1267753005987	putative metal binding site [ion binding]; other site
1267753005988	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1267753005989	active pocket/dimerization site; other site
1267753005990	active site
1267753005991	phosphorylation site [posttranslational modification]
1267753005992	Fimbrial protein; Region: Fimbrial; cl01416
1267753005993	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
1267753005994	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753005995	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753005996	fimbrial outer membrane usher protein StiC; Provisional; Region: PRK15298
1267753005997	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753005998	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753005999	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753006000	putative fimbrial protein StiH; Provisional; Region: PRK15297
1267753006001	inner membrane transport permease; Provisional; Region: PRK15066
1267753006002	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1267753006003	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1267753006004	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1267753006005	Walker A/P-loop; other site
1267753006006	ATP binding site [chemical binding]; other site
1267753006007	Q-loop/lid; other site
1267753006008	ABC transporter signature motif; other site
1267753006009	Walker B; other site
1267753006010	D-loop; other site
1267753006011	H-loop/switch region; other site
1267753006012	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1267753006013	active site clefts [active]
1267753006014	zinc binding site [ion binding]; other site
1267753006015	dimer interface [polypeptide binding]; other site
1267753006016	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1267753006017	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1267753006018	active site
1267753006019	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
1267753006020	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
1267753006021	Trp docking motif [polypeptide binding]; other site
1267753006022	putative active site [active]
1267753006023	multicopper oxidase; Provisional; Region: PRK10965
1267753006024	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1267753006025	Copper resistance protein B precursor (CopB); Region: CopB; cl01476
1267753006026	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1267753006027	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
1267753006028	spermidine synthase; Provisional; Region: PRK00811
1267753006029	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753006030	S-adenosylmethionine binding site [chemical binding]; other site
1267753006031	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
1267753006032	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753006033	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1267753006034	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753006035	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1267753006036	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
1267753006037	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1267753006038	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
1267753006039	hypothetical protein; Provisional; Region: PRK05248
1267753006040	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1267753006041	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1267753006042	substrate binding site [chemical binding]; other site
1267753006043	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1267753006044	substrate binding site [chemical binding]; other site
1267753006045	ligand binding site [chemical binding]; other site
1267753006046	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
1267753006047	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
1267753006048	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
1267753006049	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1267753006050	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753006051	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1267753006052	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
1267753006053	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1267753006054	E3 interaction surface; other site
1267753006055	lipoyl attachment site [posttranslational modification]; other site
1267753006056	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1267753006057	E3 interaction surface; other site
1267753006058	lipoyl attachment site [posttranslational modification]; other site
1267753006059	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1267753006060	E3 interaction surface; other site
1267753006061	lipoyl attachment site [posttranslational modification]; other site
1267753006062	e3 binding domain; Region: E3_binding; pfam02817
1267753006063	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1267753006064	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
1267753006065	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
1267753006066	dimer interface [polypeptide binding]; other site
1267753006067	TPP-binding site [chemical binding]; other site
1267753006068	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1267753006069	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
1267753006070	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753006071	DNA-binding site [nucleotide binding]; DNA binding site
1267753006072	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1267753006073	aromatic amino acid transporter; Provisional; Region: PRK10238
1267753006074	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1267753006075	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753006076	putative substrate translocation pore; other site
1267753006077	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
1267753006078	active site
1267753006079	regulatory protein AmpE; Provisional; Region: PRK10987
1267753006080	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
1267753006081	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1267753006082	amidase catalytic site [active]
1267753006083	Zn binding residues [ion binding]; other site
1267753006084	substrate binding site [chemical binding]; other site
1267753006085	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
1267753006086	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1267753006087	dimerization interface [polypeptide binding]; other site
1267753006088	active site
1267753006089	putative major pilin subunit; Provisional; Region: PRK10574
1267753006090	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1267753006091	Pilin (bacterial filament); Region: Pilin; pfam00114
1267753006092	hypothetical protein; Provisional; Region: PRK10436
1267753006093	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1267753006094	Walker A motif; other site
1267753006095	ATP binding site [chemical binding]; other site
1267753006096	Walker B motif; other site
1267753006097	type IV pilin biogenesis protein; Provisional; Region: PRK10573
1267753006098	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1267753006099	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1267753006100	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
1267753006101	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1267753006102	active site
1267753006103	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1267753006104	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1267753006105	CoA-binding site [chemical binding]; other site
1267753006106	ATP-binding [chemical binding]; other site
1267753006107	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
1267753006108	DNA gyrase inhibitor; Reviewed; Region: PRK00418
1267753006109	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1267753006110	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
1267753006111	active site
1267753006112	8-oxo-dGMP binding site [chemical binding]; other site
1267753006113	nudix motif; other site
1267753006114	metal binding site [ion binding]; metal-binding site
1267753006115	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1267753006116	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1267753006117	SEC-C motif; Region: SEC-C; pfam02810
1267753006118	SecA regulator SecM; Provisional; Region: PRK02943
1267753006119	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1267753006120	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1267753006121	cell division protein FtsZ; Validated; Region: PRK09330
1267753006122	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1267753006123	nucleotide binding site [chemical binding]; other site
1267753006124	SulA interaction site; other site
1267753006125	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
1267753006126	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
1267753006127	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1267753006128	Cell division protein FtsA; Region: FtsA; pfam14450
1267753006129	cell division protein FtsQ; Provisional; Region: PRK10775
1267753006130	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1267753006131	Cell division protein FtsQ; Region: FtsQ; pfam03799
1267753006132	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1267753006133	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1267753006134	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1267753006135	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1267753006136	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1267753006137	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1267753006138	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1267753006139	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1267753006140	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1267753006141	active site
1267753006142	homodimer interface [polypeptide binding]; other site
1267753006143	cell division protein FtsW; Provisional; Region: PRK10774
1267753006144	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
1267753006145	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1267753006146	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1267753006147	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1267753006148	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1267753006149	Mg++ binding site [ion binding]; other site
1267753006150	putative catalytic motif [active]
1267753006151	putative substrate binding site [chemical binding]; other site
1267753006152	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
1267753006153	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1267753006154	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1267753006155	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1267753006156	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1267753006157	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1267753006158	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1267753006159	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1267753006160	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
1267753006161	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1267753006162	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1267753006163	cell division protein FtsL; Provisional; Region: PRK10772
1267753006164	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
1267753006165	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1267753006166	mraZ protein; Region: TIGR00242
1267753006167	MraZ protein; Region: MraZ; pfam02381
1267753006168	MraZ protein; Region: MraZ; pfam02381
1267753006169	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
1267753006170	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753006171	DNA binding site [nucleotide binding]
1267753006172	domain linker motif; other site
1267753006173	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
1267753006174	dimerization interface [polypeptide binding]; other site
1267753006175	ligand binding site [chemical binding]; other site
1267753006176	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1267753006177	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1267753006178	putative valine binding site [chemical binding]; other site
1267753006179	dimer interface [polypeptide binding]; other site
1267753006180	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1267753006181	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
1267753006182	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1267753006183	PYR/PP interface [polypeptide binding]; other site
1267753006184	dimer interface [polypeptide binding]; other site
1267753006185	TPP binding site [chemical binding]; other site
1267753006186	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1267753006187	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1267753006188	TPP-binding site [chemical binding]; other site
1267753006189	dimer interface [polypeptide binding]; other site
1267753006190	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
1267753006191	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753006192	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
1267753006193	putative substrate binding pocket [chemical binding]; other site
1267753006194	putative dimerization interface [polypeptide binding]; other site
1267753006195	leu operon leader peptide; Provisional; Region: PRK14744
1267753006196	2-isopropylmalate synthase; Validated; Region: PRK00915
1267753006197	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1267753006198	active site
1267753006199	catalytic residues [active]
1267753006200	metal binding site [ion binding]; metal-binding site
1267753006201	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1267753006202	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1267753006203	tartrate dehydrogenase; Region: TTC; TIGR02089
1267753006204	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1267753006205	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1267753006206	substrate binding site [chemical binding]; other site
1267753006207	ligand binding site [chemical binding]; other site
1267753006208	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1267753006209	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1267753006210	substrate binding site [chemical binding]; other site
1267753006211	transcriptional regulator SgrR; Provisional; Region: PRK13626
1267753006212	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1267753006213	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1267753006214	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
1267753006215	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1267753006216	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
1267753006217	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753006218	dimer interface [polypeptide binding]; other site
1267753006219	conserved gate region; other site
1267753006220	putative PBP binding loops; other site
1267753006221	ABC-ATPase subunit interface; other site
1267753006222	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753006223	dimer interface [polypeptide binding]; other site
1267753006224	conserved gate region; other site
1267753006225	putative PBP binding loops; other site
1267753006226	ABC-ATPase subunit interface; other site
1267753006227	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
1267753006228	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
1267753006229	Walker A/P-loop; other site
1267753006230	ATP binding site [chemical binding]; other site
1267753006231	Q-loop/lid; other site
1267753006232	ABC transporter signature motif; other site
1267753006233	Walker B; other site
1267753006234	D-loop; other site
1267753006235	H-loop/switch region; other site
1267753006236	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1267753006237	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1267753006238	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
1267753006239	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1267753006240	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753006241	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753006242	ribulokinase; Provisional; Region: PRK04123
1267753006243	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
1267753006244	N- and C-terminal domain interface [polypeptide binding]; other site
1267753006245	active site
1267753006246	MgATP binding site [chemical binding]; other site
1267753006247	catalytic site [active]
1267753006248	metal binding site [ion binding]; metal-binding site
1267753006249	carbohydrate binding site [chemical binding]; other site
1267753006250	homodimer interface [polypeptide binding]; other site
1267753006251	L-arabinose isomerase; Provisional; Region: PRK02929
1267753006252	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
1267753006253	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
1267753006254	trimer interface [polypeptide binding]; other site
1267753006255	putative substrate binding site [chemical binding]; other site
1267753006256	putative metal binding site [ion binding]; other site
1267753006257	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1267753006258	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1267753006259	intersubunit interface [polypeptide binding]; other site
1267753006260	active site
1267753006261	Zn2+ binding site [ion binding]; other site
1267753006262	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1267753006263	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1267753006264	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1267753006265	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1267753006266	Probable transposase; Region: OrfB_IS605; pfam01385
1267753006267	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1267753006268	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1267753006269	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cl00630
1267753006270	putative active site [active]
1267753006271	DNA polymerase II; Reviewed; Region: PRK05762
1267753006272	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
1267753006273	active site
1267753006274	catalytic site [active]
1267753006275	substrate binding site [chemical binding]; other site
1267753006276	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
1267753006277	active site
1267753006278	metal-binding site
1267753006279	ATP-dependent helicase HepA; Validated; Region: PRK04914
1267753006280	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753006281	ATP binding site [chemical binding]; other site
1267753006282	putative Mg++ binding site [ion binding]; other site
1267753006283	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753006284	nucleotide binding region [chemical binding]; other site
1267753006285	ATP-binding site [chemical binding]; other site
1267753006286	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1267753006287	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1267753006288	active site
1267753006289	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
1267753006290	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1267753006291	putative metal binding site [ion binding]; other site
1267753006292	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1267753006293	HSP70 interaction site [polypeptide binding]; other site
1267753006294	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1267753006295	OstA-like protein; Region: OstA; pfam03968
1267753006296	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1267753006297	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
1267753006298	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
1267753006299	SurA N-terminal domain; Region: SurA_N; pfam09312
1267753006300	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1267753006301	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1267753006302	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
1267753006303	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1267753006304	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1267753006305	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1267753006306	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1267753006307	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
1267753006308	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
1267753006309	active site
1267753006310	metal binding site [ion binding]; metal-binding site
1267753006311	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1267753006312	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1267753006313	folate binding site [chemical binding]; other site
1267753006314	NADP+ binding site [chemical binding]; other site
1267753006315	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
1267753006316	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
1267753006317	TrkA-N domain; Region: TrkA_N; pfam02254
1267753006318	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
1267753006319	Sulfatase; Region: Sulfatase; cl17466
1267753006320	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1267753006321	Sulfatase; Region: Sulfatase; cl17466
1267753006322	Sulfatase; Region: Sulfatase; cl17466
1267753006323	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753006324	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1267753006325	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753006326	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1267753006327	putative substrate translocation pore; other site
1267753006328	ferredoxin-like protein FixX; Provisional; Region: PRK15449
1267753006329	putative oxidoreductase FixC; Provisional; Region: PRK10157
1267753006330	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1267753006331	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
1267753006332	Electron transfer flavoprotein domain; Region: ETF; smart00893
1267753006333	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1267753006334	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1267753006335	Ligand binding site [chemical binding]; other site
1267753006336	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1267753006337	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
1267753006338	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
1267753006339	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
1267753006340	active site
1267753006341	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
1267753006342	CoA-transferase family III; Region: CoA_transf_3; pfam02515
1267753006343	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
1267753006344	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
1267753006345	acyl-activating enzyme (AAE) consensus motif; other site
1267753006346	putative AMP binding site [chemical binding]; other site
1267753006347	putative active site [active]
1267753006348	putative CoA binding site [chemical binding]; other site
1267753006349	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
1267753006350	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1267753006351	substrate binding site [chemical binding]; other site
1267753006352	oxyanion hole (OAH) forming residues; other site
1267753006353	trimer interface [polypeptide binding]; other site
1267753006354	carnitine operon protein CaiE; Provisional; Region: PRK13627
1267753006355	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
1267753006356	putative trimer interface [polypeptide binding]; other site
1267753006357	putative metal binding site [ion binding]; other site
1267753006358	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
1267753006359	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1267753006360	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1267753006361	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1267753006362	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1267753006363	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1267753006364	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1267753006365	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1267753006366	IMP binding site; other site
1267753006367	dimer interface [polypeptide binding]; other site
1267753006368	interdomain contacts; other site
1267753006369	partial ornithine binding site; other site
1267753006370	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; cl03056
1267753006371	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1267753006372	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1267753006373	catalytic site [active]
1267753006374	subunit interface [polypeptide binding]; other site
1267753006375	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1267753006376	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
1267753006377	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1267753006378	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1267753006379	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
1267753006380	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
1267753006381	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
1267753006382	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1267753006383	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
1267753006384	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
1267753006385	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
1267753006386	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
1267753006387	putative active site [active]
1267753006388	(T/H)XGH motif; other site
1267753006389	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
1267753006390	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1267753006391	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1267753006392	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1267753006393	active site
1267753006394	catalytic residues [active]
1267753006395	metal binding site [ion binding]; metal-binding site
1267753006396	homodimer binding site [polypeptide binding]; other site
1267753006397	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1267753006398	carboxyltransferase (CT) interaction site; other site
1267753006399	biotinylation site [posttranslational modification]; other site
1267753006400	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1267753006401	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1267753006402	PAS domain; Region: PAS; smart00091
1267753006403	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753006404	ATP binding site [chemical binding]; other site
1267753006405	Mg2+ binding site [ion binding]; other site
1267753006406	G-X-G motif; other site
1267753006407	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
1267753006408	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753006409	active site
1267753006410	phosphorylation site [posttranslational modification]
1267753006411	intermolecular recognition site; other site
1267753006412	dimerization interface [polypeptide binding]; other site
1267753006413	Transcriptional regulator; Region: CitT; pfam12431
1267753006414	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
1267753006415	active site
1267753006416	tetramer interface [polypeptide binding]; other site
1267753006417	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1267753006418	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1267753006419	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1267753006420	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1267753006421	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1267753006422	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1267753006423	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1267753006424	active site
1267753006425	HIGH motif; other site
1267753006426	nucleotide binding site [chemical binding]; other site
1267753006427	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1267753006428	active site
1267753006429	KMSKS motif; other site
1267753006430	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1267753006431	tRNA binding surface [nucleotide binding]; other site
1267753006432	anticodon binding site; other site
1267753006433	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1267753006434	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1267753006435	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1267753006436	active site
1267753006437	Riboflavin kinase; Region: Flavokinase; smart00904
1267753006438	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
1267753006439	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1267753006440	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1267753006441	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1267753006442	putative alpha-glucosidase; Provisional; Region: PRK10658
1267753006443	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1267753006444	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
1267753006445	putative active site [active]
1267753006446	putative catalytic site [active]
1267753006447	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
1267753006448	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753006449	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
1267753006450	putative dimerization interface [polypeptide binding]; other site
1267753006451	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1267753006452	potential frameshift: common BLAST hit: gi|386589920|ref|YP_006086320.1| transposase
1267753006453	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1267753006454	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753006455	FeS/SAM binding site; other site
1267753006456	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1267753006457	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1267753006458	Sulfatase; Region: Sulfatase; pfam00884
1267753006459	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
1267753006460	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1267753006461	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
1267753006462	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1267753006463	catalytic residues [active]
1267753006464	fimbrial chaperone BcfG; Provisional; Region: PRK15192
1267753006465	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753006466	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753006467	fimbrial protein BcfF; Provisional; Region: PRK15191
1267753006468	fimbrial protein BcfE; Provisional; Region: PRK15190
1267753006469	fimbrial protein BcfD; Provisional; Region: PRK15189
1267753006470	outer membrane usher protein; Provisional; Region: PRK15193
1267753006471	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753006472	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753006473	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753006474	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
1267753006475	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753006476	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753006477	fimbrial protein BcfA; Provisional; Region: PRK15187
1267753006478	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1267753006479	Helix-turn-helix domain; Region: HTH_36; pfam13730
1267753006480	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1267753006481	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
1267753006482	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
1267753006483	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
1267753006484	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753006485	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753006486	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1267753006487	substrate binding pocket [chemical binding]; other site
1267753006488	dimerization interface [polypeptide binding]; other site
1267753006489	chaperone protein DnaJ; Provisional; Region: PRK10767
1267753006490	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1267753006491	HSP70 interaction site [polypeptide binding]; other site
1267753006492	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1267753006493	substrate binding site [polypeptide binding]; other site
1267753006494	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1267753006495	Zn binding sites [ion binding]; other site
1267753006496	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1267753006497	dimer interface [polypeptide binding]; other site
1267753006498	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1267753006499	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1267753006500	nucleotide binding site [chemical binding]; other site
1267753006501	hypothetical protein; Provisional; Region: PRK10154
1267753006502	hypothetical protein; Provisional; Region: PRK10236
1267753006503	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
1267753006504	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
1267753006505	hypothetical protein; Provisional; Region: PRK10659
1267753006506	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1267753006507	MPT binding site; other site
1267753006508	trimer interface [polypeptide binding]; other site
1267753006509	transaldolase-like protein; Provisional; Region: PTZ00411
1267753006510	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1267753006511	active site
1267753006512	dimer interface [polypeptide binding]; other site
1267753006513	catalytic residue [active]
1267753006514	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1267753006515	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1267753006516	hypothetical protein; Validated; Region: PRK02101
1267753006517	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1267753006518	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1267753006519	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753006520	catalytic residue [active]
1267753006521	homoserine kinase; Provisional; Region: PRK01212
1267753006522	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1267753006523	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1267753006524	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1267753006525	putative catalytic residues [active]
1267753006526	putative nucleotide binding site [chemical binding]; other site
1267753006527	putative aspartate binding site [chemical binding]; other site
1267753006528	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1267753006529	dimer interface [polypeptide binding]; other site
1267753006530	putative threonine allosteric regulatory site; other site
1267753006531	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1267753006532	putative threonine allosteric regulatory site; other site
1267753006533	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1267753006534	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1267753006535	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
1267753006536	putative RNA methyltransferase; Provisional; Region: PRK10433
1267753006537	two-component response regulator; Provisional; Region: PRK11173
1267753006538	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753006539	active site
1267753006540	phosphorylation site [posttranslational modification]
1267753006541	intermolecular recognition site; other site
1267753006542	dimerization interface [polypeptide binding]; other site
1267753006543	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753006544	DNA binding site [nucleotide binding]
1267753006545	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
1267753006546	Helix-turn-helix domain; Region: HTH_36; pfam13730
1267753006547	putative fimbrial protein SthA; Provisional; Region: PRK15296
1267753006548	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
1267753006549	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753006550	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753006551	putative fimbrial outer membrane usher protein SthC; Provisional; Region: PRK15294
1267753006552	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753006553	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753006554	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753006555	putative fimbrial protein SthD; Provisional; Region: PRK15293
1267753006556	putative major fimbrial protein SthE; Provisional; Region: PRK15292
1267753006557	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
1267753006558	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
1267753006559	sensory histidine kinase CreC; Provisional; Region: PRK11100
1267753006560	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1267753006561	dimerization interface [polypeptide binding]; other site
1267753006562	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753006563	dimer interface [polypeptide binding]; other site
1267753006564	phosphorylation site [posttranslational modification]
1267753006565	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753006566	ATP binding site [chemical binding]; other site
1267753006567	Mg2+ binding site [ion binding]; other site
1267753006568	G-X-G motif; other site
1267753006569	DNA-binding response regulator CreB; Provisional; Region: PRK11083
1267753006570	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753006571	active site
1267753006572	phosphorylation site [posttranslational modification]
1267753006573	intermolecular recognition site; other site
1267753006574	dimerization interface [polypeptide binding]; other site
1267753006575	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753006576	DNA binding site [nucleotide binding]
1267753006577	hypothetical protein; Provisional; Region: PRK10756
1267753006578	CreA protein; Region: CreA; pfam05981
1267753006579	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
1267753006580	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753006581	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1267753006582	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1267753006583	catalytic core [active]
1267753006584	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
1267753006585	Trp operon repressor; Provisional; Region: PRK01381
1267753006586	lytic murein transglycosylase; Provisional; Region: PRK11619
1267753006587	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1267753006588	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1267753006589	catalytic residue [active]
1267753006590	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1267753006591	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753006592	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753006593	ABC transporter; Region: ABC_tran_2; pfam12848
1267753006594	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753006595	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753006596	non-specific DNA binding site [nucleotide binding]; other site
1267753006597	salt bridge; other site
1267753006598	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
1267753006599	sequence-specific DNA binding site [nucleotide binding]; other site
1267753006600	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
1267753006601	active site
1267753006602	(T/H)XGH motif; other site
1267753006603	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1267753006604	DNA repair protein RadA; Region: sms; TIGR00416
1267753006605	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1267753006606	Walker A motif/ATP binding site; other site
1267753006607	ATP binding site [chemical binding]; other site
1267753006608	Walker B motif; other site
1267753006609	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1267753006610	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
1267753006611	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753006612	motif II; other site
1267753006613	hypothetical protein; Provisional; Region: PRK11246
1267753006614	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
1267753006615	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1267753006616	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1267753006617	hypothetical protein; Provisional; Region: PRK15303
1267753006618	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
1267753006619	putative fimbrial chaperone protein; Provisional; Region: PRK09918
1267753006620	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753006621	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753006622	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
1267753006623	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753006624	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753006625	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753006626	hypothetical protein; Provisional; Region: PRK15301
1267753006627	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1267753006628	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1267753006629	phosphopentomutase; Provisional; Region: PRK05362
1267753006630	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1267753006631	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
1267753006632	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1267753006633	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1267753006634	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1267753006635	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1267753006636	intersubunit interface [polypeptide binding]; other site
1267753006637	active site
1267753006638	catalytic residue [active]
1267753006639	hypothetical protein; Provisional; Region: PRK10977
1267753006640	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
1267753006641	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753006642	FeS/SAM binding site; other site
1267753006643	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1267753006644	active site
1267753006645	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
1267753006646	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
1267753006647	active site
1267753006648	nucleophile elbow; other site
1267753006649	periplasmic protein; Provisional; Region: PRK10568
1267753006650	BON domain; Region: BON; pfam04972
1267753006651	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1267753006652	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1267753006653	G1 box; other site
1267753006654	putative GEF interaction site [polypeptide binding]; other site
1267753006655	GTP/Mg2+ binding site [chemical binding]; other site
1267753006656	Switch I region; other site
1267753006657	G2 box; other site
1267753006658	G3 box; other site
1267753006659	Switch II region; other site
1267753006660	G4 box; other site
1267753006661	G5 box; other site
1267753006662	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1267753006663	dUMP phosphatase; Provisional; Region: PRK09449
1267753006664	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753006665	motif II; other site
1267753006666	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
1267753006667	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753006668	Coenzyme A binding pocket [chemical binding]; other site
1267753006669	DNA polymerase III subunit psi; Validated; Region: PRK06856
1267753006670	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
1267753006671	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
1267753006672	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753006673	S-adenosylmethionine binding site [chemical binding]; other site
1267753006674	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
1267753006675	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1267753006676	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753006677	metal binding site [ion binding]; metal-binding site
1267753006678	active site
1267753006679	I-site; other site
1267753006680	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
1267753006681	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
1267753006682	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
1267753006683	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1267753006684	putative deacylase active site [active]
1267753006685	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
1267753006686	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753006687	DNA binding residues [nucleotide binding]
1267753006688	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1267753006689	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753006690	DNA binding residues [nucleotide binding]
1267753006691	dimerization interface [polypeptide binding]; other site
1267753006692	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1267753006693	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1267753006694	hypothetical protein; Provisional; Region: PRK09917
1267753006695	primosomal protein DnaI; Provisional; Region: PRK02854
1267753006696	DNA replication protein DnaC; Validated; Region: PRK07952
1267753006697	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753006698	Walker A motif; other site
1267753006699	ATP binding site [chemical binding]; other site
1267753006700	Walker B motif; other site
1267753006701	hypothetical protein; Provisional; Region: PRK11667
1267753006702	phosphoglycerol transferase I; Provisional; Region: PRK03776
1267753006703	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1267753006704	methyl-accepting protein IV; Provisional; Region: PRK09793
1267753006705	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1267753006706	dimer interface [polypeptide binding]; other site
1267753006707	ligand binding site [chemical binding]; other site
1267753006708	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753006709	dimerization interface [polypeptide binding]; other site
1267753006710	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1267753006711	dimer interface [polypeptide binding]; other site
1267753006712	putative CheW interface [polypeptide binding]; other site
1267753006713	carbon starvation protein A; Provisional; Region: PRK15015
1267753006714	Carbon starvation protein CstA; Region: CstA; pfam02554
1267753006715	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1267753006716	Uncharacterized small protein [Function unknown]; Region: COG2879
1267753006717	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
1267753006718	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
1267753006719	P-loop, Walker A motif; other site
1267753006720	Base recognition motif; other site
1267753006721	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1267753006722	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1267753006723	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1267753006724	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753006725	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
1267753006726	Protein of unknown function DUF91; Region: DUF91; cl00709
1267753006727	Uncharacterized conserved protein [Function unknown]; Region: COG3586
1267753006728	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
1267753006729	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1267753006730	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1267753006731	NAD(P) binding site [chemical binding]; other site
1267753006732	catalytic residues [active]
1267753006733	putative transposase; Provisional; Region: PRK09857
1267753006734	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1267753006735	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
1267753006736	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753006737	putative substrate translocation pore; other site
1267753006738	Predicted membrane protein [Function unknown]; Region: COG2733
1267753006739	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
1267753006740	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1267753006741	Nucleoside recognition; Region: Gate; pfam07670
1267753006742	hypothetical protein; Provisional; Region: PRK10519
1267753006743	isoaspartyl dipeptidase; Provisional; Region: PRK10657
1267753006744	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1267753006745	active site
1267753006746	cell density-dependent motility repressor; Provisional; Region: PRK10082
1267753006747	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753006748	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1267753006749	dimerization interface [polypeptide binding]; other site
1267753006750	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1267753006751	aspartate racemase; Region: asp_race; TIGR00035
1267753006752	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1267753006753	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1267753006754	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1267753006755	active site
1267753006756	HIGH motif; other site
1267753006757	dimer interface [polypeptide binding]; other site
1267753006758	KMSKS motif; other site
1267753006759	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
1267753006760	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753006761	DNA-binding site [nucleotide binding]; DNA binding site
1267753006762	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1267753006763	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1267753006764	Uncharacterized conserved protein [Function unknown]; Region: COG3439
1267753006765	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
1267753006766	hypothetical protein; Provisional; Region: PRK13687
1267753006767	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1267753006768	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753006769	S-adenosylmethionine binding site [chemical binding]; other site
1267753006770	hypothetical protein; Provisional; Region: PRK12378
1267753006771	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
1267753006772	HNH endonuclease; Region: HNH_2; pfam13391
1267753006773	Uncharacterized conserved protein [Function unknown]; Region: COG4127
1267753006774	Restriction endonuclease; Region: Mrr_cat; pfam04471
1267753006775	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
1267753006776	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
1267753006777	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1267753006778	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1267753006779	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1267753006780	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1267753006781	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1267753006782	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1267753006783	Protein of unknown function DUF262; Region: DUF262; pfam03235
1267753006784	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1267753006785	Protein of unknown function DUF262; Region: DUF262; pfam03235
1267753006786	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1267753006787	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1267753006788	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
1267753006789	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1267753006790	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753006791	ATP binding site [chemical binding]; other site
1267753006792	putative Mg++ binding site [ion binding]; other site
1267753006793	Protein of unknown function DUF45; Region: DUF45; pfam01863
1267753006794	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1267753006795	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1267753006796	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1267753006797	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1267753006798	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1267753006799	integrase; Provisional; Region: PRK09692
1267753006800	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1267753006801	active site
1267753006802	Int/Topo IB signature motif; other site
1267753006803	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1267753006804	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1267753006805	putative NAD(P) binding site [chemical binding]; other site
1267753006806	putative substrate binding site [chemical binding]; other site
1267753006807	catalytic Zn binding site [ion binding]; other site
1267753006808	structural Zn binding site [ion binding]; other site
1267753006809	dimer interface [polypeptide binding]; other site
1267753006810	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1267753006811	ATP-binding site [chemical binding]; other site
1267753006812	Gluconate-6-phosphate binding site [chemical binding]; other site
1267753006813	Shikimate kinase; Region: SKI; pfam01202
1267753006814	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
1267753006815	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
1267753006816	putative NAD(P) binding site [chemical binding]; other site
1267753006817	catalytic Zn binding site [ion binding]; other site
1267753006818	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
1267753006819	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1267753006820	NADP binding site [chemical binding]; other site
1267753006821	homodimer interface [polypeptide binding]; other site
1267753006822	active site
1267753006823	gluconate transporter; Region: gntP; TIGR00791
1267753006824	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1267753006825	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1267753006826	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753006827	DNA binding site [nucleotide binding]
1267753006828	domain linker motif; other site
1267753006829	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1267753006830	putative dimerization interface [polypeptide binding]; other site
1267753006831	putative ligand binding site [chemical binding]; other site
1267753006832	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
1267753006833	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1267753006834	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
1267753006835	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1267753006836	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1267753006837	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1267753006838	interface (dimer of trimers) [polypeptide binding]; other site
1267753006839	Substrate-binding/catalytic site; other site
1267753006840	Zn-binding sites [ion binding]; other site
1267753006841	DNA polymerase III subunit chi; Validated; Region: PRK05728
1267753006842	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1267753006843	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1267753006844	HIGH motif; other site
1267753006845	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1267753006846	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1267753006847	active site
1267753006848	KMSKS motif; other site
1267753006849	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1267753006850	tRNA binding surface [nucleotide binding]; other site
1267753006851	anticodon binding site; other site
1267753006852	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1267753006853	Predicted membrane protein [Function unknown]; Region: COG4269
1267753006854	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1267753006855	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753006856	Coenzyme A binding pocket [chemical binding]; other site
1267753006857	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
1267753006858	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1267753006859	active site
1267753006860	dinuclear metal binding site [ion binding]; other site
1267753006861	dimerization interface [polypeptide binding]; other site
1267753006862	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
1267753006863	RNase E inhibitor protein; Provisional; Region: PRK11191
1267753006864	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
1267753006865	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1267753006866	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1267753006867	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1267753006868	arginine deiminase; Provisional; Region: PRK01388
1267753006869	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
1267753006870	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
1267753006871	putative substrate binding site [chemical binding]; other site
1267753006872	nucleotide binding site [chemical binding]; other site
1267753006873	nucleotide binding site [chemical binding]; other site
1267753006874	homodimer interface [polypeptide binding]; other site
1267753006875	ornithine carbamoyltransferase; Validated; Region: PRK02102
1267753006876	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1267753006877	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1267753006878	Predicted membrane protein [Function unknown]; Region: COG1288
1267753006879	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1267753006880	Arginine repressor [Transcription]; Region: ArgR; COG1438
1267753006881	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1267753006882	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1267753006883	pyrBI operon leader peptide; Provisional; Region: PRK10224
1267753006884	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
1267753006885	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1267753006886	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1267753006887	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1267753006888	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1267753006889	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1267753006890	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1267753006891	homotrimer interaction site [polypeptide binding]; other site
1267753006892	putative active site [active]
1267753006893	Transposase; Region: HTH_Tnp_1; cl17663
1267753006894	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
1267753006895	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1267753006896	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1267753006897	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1267753006898	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1267753006899	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1267753006900	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1267753006901	trehalose repressor; Provisional; Region: treR; PRK09492
1267753006902	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753006903	DNA binding site [nucleotide binding]
1267753006904	domain linker motif; other site
1267753006905	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
1267753006906	dimerization interface [polypeptide binding]; other site
1267753006907	ligand binding site [chemical binding]; other site
1267753006908	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
1267753006909	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1267753006910	active site turn [active]
1267753006911	phosphorylation site [posttranslational modification]
1267753006912	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1267753006913	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
1267753006914	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1267753006915	Ca binding site [ion binding]; other site
1267753006916	active site
1267753006917	catalytic site [active]
1267753006918	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1267753006919	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
1267753006920	ATP cone domain; Region: ATP-cone; pfam03477
1267753006921	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1267753006922	effector binding site; other site
1267753006923	active site
1267753006924	Zn binding site [ion binding]; other site
1267753006925	glycine loop; other site
1267753006926	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1267753006927	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753006928	FeS/SAM binding site; other site
1267753006929	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
1267753006930	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
1267753006931	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1267753006932	HTH domain; Region: HTH_11; pfam08279
1267753006933	Mga helix-turn-helix domain; Region: Mga; pfam05043
1267753006934	PRD domain; Region: PRD; pfam00874
1267753006935	PRD domain; Region: PRD; pfam00874
1267753006936	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1267753006937	active site
1267753006938	P-loop; other site
1267753006939	phosphorylation site [posttranslational modification]
1267753006940	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753006941	active site
1267753006942	phosphorylation site [posttranslational modification]
1267753006943	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
1267753006944	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1267753006945	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
1267753006946	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
1267753006947	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1267753006948	active site
1267753006949	Domain of unknown function (DUF4310); Region: DUF4310; cl11918
1267753006950	Domain of unknown function (DUF4310); Region: DUF4310; cl11918
1267753006951	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
1267753006952	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
1267753006953	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
1267753006954	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
1267753006955	cytochrome b562; Provisional; Region: PRK15058
1267753006956	peptidase PmbA; Provisional; Region: PRK11040
1267753006957	hypothetical protein; Provisional; Region: PRK05255
1267753006958	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
1267753006959	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1267753006960	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1267753006961	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1267753006962	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1267753006963	AMP binding site [chemical binding]; other site
1267753006964	metal binding site [ion binding]; metal-binding site
1267753006965	active site
1267753006966	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1267753006967	dimer interface [polypeptide binding]; other site
1267753006968	substrate binding site [chemical binding]; other site
1267753006969	metal binding sites [ion binding]; metal-binding site
1267753006970	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
1267753006971	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
1267753006972	active site
1267753006973	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753006974	putative substrate translocation pore; other site
1267753006975	D-galactonate transporter; Region: 2A0114; TIGR00893
1267753006976	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1267753006977	putative active site pocket [active]
1267753006978	dimerization interface [polypeptide binding]; other site
1267753006979	putative catalytic residue [active]
1267753006980	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
1267753006981	Family of unknown function (DUF490); Region: DUF490; pfam04357
1267753006982	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
1267753006983	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1267753006984	Surface antigen; Region: Bac_surface_Ag; pfam01103
1267753006985	methionine sulfoxide reductase A; Provisional; Region: PRK00058
1267753006986	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1267753006987	Domain of unknown function DUF21; Region: DUF21; pfam01595
1267753006988	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1267753006989	Transporter associated domain; Region: CorC_HlyC; smart01091
1267753006990	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
1267753006991	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
1267753006992	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1267753006993	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1267753006994	active site
1267753006995	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1267753006996	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1267753006997	active site
1267753006998	metal binding site [ion binding]; metal-binding site
1267753006999	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1267753007000	Predicted transcriptional regulators [Transcription]; Region: COG1733
1267753007001	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1267753007002	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1267753007003	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
1267753007004	NADP binding site [chemical binding]; other site
1267753007005	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1267753007006	EamA-like transporter family; Region: EamA; pfam00892
1267753007007	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
1267753007008	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1267753007009	Hemerythrin-like domain; Region: Hr-like; cd12108
1267753007010	Fe binding site [ion binding]; other site
1267753007011	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
1267753007012	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
1267753007013	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1267753007014	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1267753007015	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
1267753007016	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
1267753007017	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1267753007018	EamA-like transporter family; Region: EamA; pfam00892
1267753007019	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1267753007020	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1267753007021	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1267753007022	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1267753007023	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1267753007024	dimer interface [polypeptide binding]; other site
1267753007025	ssDNA binding site [nucleotide binding]; other site
1267753007026	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1267753007027	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1267753007028	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753007029	Protein of unknown function (DUF1440); Region: DUF1440; cl01380
1267753007030	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1267753007031	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1267753007032	intersubunit interface [polypeptide binding]; other site
1267753007033	active site
1267753007034	Zn2+ binding site [ion binding]; other site
1267753007035	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
1267753007036	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1267753007037	AP (apurinic/apyrimidinic) site pocket; other site
1267753007038	DNA interaction; other site
1267753007039	Metal-binding active site; metal-binding site
1267753007040	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1267753007041	active site
1267753007042	dimer interface [polypeptide binding]; other site
1267753007043	magnesium binding site [ion binding]; other site
1267753007044	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753007045	active site
1267753007046	phosphorylation site [posttranslational modification]
1267753007047	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1267753007048	active site
1267753007049	P-loop; other site
1267753007050	phosphorylation site [posttranslational modification]
1267753007051	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
1267753007052	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
1267753007053	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
1267753007054	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1267753007055	transcriptional repressor UlaR; Provisional; Region: PRK13509
1267753007056	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1267753007057	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753007058	esterase; Provisional; Region: PRK10566
1267753007059	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1267753007060	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1267753007061	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
1267753007062	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753007063	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
1267753007064	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
1267753007065	FAD binding site [chemical binding]; other site
1267753007066	substrate binding site [chemical binding]; other site
1267753007067	catalytic residues [active]
1267753007068	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1267753007069	Predicted integral membrane protein [Function unknown]; Region: COG5463
1267753007070	Predicted membrane protein [Function unknown]; Region: COG3766
1267753007071	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1267753007072	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1267753007073	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
1267753007074	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1267753007075	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
1267753007076	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
1267753007077	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1267753007078	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1267753007079	exoribonuclease R; Provisional; Region: PRK11642
1267753007080	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1267753007081	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1267753007082	RNB domain; Region: RNB; pfam00773
1267753007083	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1267753007084	RNA binding site [nucleotide binding]; other site
1267753007085	Predicted transcriptional regulator [Transcription]; Region: COG1959
1267753007086	transcriptional repressor NsrR; Provisional; Region: PRK11014
1267753007087	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1267753007088	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1267753007089	GDP-binding site [chemical binding]; other site
1267753007090	ACT binding site; other site
1267753007091	IMP binding site; other site
1267753007092	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
1267753007093	FtsH protease regulator HflC; Provisional; Region: PRK11029
1267753007094	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
1267753007095	FtsH protease regulator HflK; Provisional; Region: PRK10930
1267753007096	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
1267753007097	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
1267753007098	GTPase HflX; Provisional; Region: PRK11058
1267753007099	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1267753007100	HflX GTPase family; Region: HflX; cd01878
1267753007101	G1 box; other site
1267753007102	GTP/Mg2+ binding site [chemical binding]; other site
1267753007103	Switch I region; other site
1267753007104	G2 box; other site
1267753007105	G3 box; other site
1267753007106	Switch II region; other site
1267753007107	G4 box; other site
1267753007108	G5 box; other site
1267753007109	bacterial Hfq-like; Region: Hfq; cd01716
1267753007110	hexamer interface [polypeptide binding]; other site
1267753007111	Sm1 motif; other site
1267753007112	RNA binding site [nucleotide binding]; other site
1267753007113	Sm2 motif; other site
1267753007114	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1267753007115	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1267753007116	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1267753007117	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753007118	ATP binding site [chemical binding]; other site
1267753007119	Mg2+ binding site [ion binding]; other site
1267753007120	G-X-G motif; other site
1267753007121	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
1267753007122	ATP binding site [chemical binding]; other site
1267753007123	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1267753007124	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
1267753007125	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1267753007126	active site
1267753007127	metal binding site [ion binding]; metal-binding site
1267753007128	ADP-binding protein; Provisional; Region: PRK10646
1267753007129	putative carbohydrate kinase; Provisional; Region: PRK10565
1267753007130	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1267753007131	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1267753007132	putative substrate binding site [chemical binding]; other site
1267753007133	putative ATP binding site [chemical binding]; other site
1267753007134	epoxyqueuosine reductase; Region: TIGR00276
1267753007135	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1267753007136	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
1267753007137	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753007138	substrate binding pocket [chemical binding]; other site
1267753007139	membrane-bound complex binding site; other site
1267753007140	hinge residues; other site
1267753007141	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
1267753007142	catalytic site [active]
1267753007143	putative active site [active]
1267753007144	putative substrate binding site [chemical binding]; other site
1267753007145	dimer interface [polypeptide binding]; other site
1267753007146	GTPase RsgA; Reviewed; Region: PRK12288
1267753007147	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1267753007148	RNA binding site [nucleotide binding]; other site
1267753007149	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1267753007150	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1267753007151	GTP/Mg2+ binding site [chemical binding]; other site
1267753007152	G4 box; other site
1267753007153	G5 box; other site
1267753007154	G1 box; other site
1267753007155	Switch I region; other site
1267753007156	G2 box; other site
1267753007157	G3 box; other site
1267753007158	Switch II region; other site
1267753007159	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
1267753007160	putative mechanosensitive channel protein; Provisional; Region: PRK10929
1267753007161	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
1267753007162	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1267753007163	inner membrane transporter YjeM; Provisional; Region: PRK15238
1267753007164	poxB regulator PoxA; Provisional; Region: PRK09350
1267753007165	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1267753007166	motif 1; other site
1267753007167	dimer interface [polypeptide binding]; other site
1267753007168	active site
1267753007169	motif 2; other site
1267753007170	motif 3; other site
1267753007171	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
1267753007172	L-aspartate oxidase; Provisional; Region: PRK06175
1267753007173	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1267753007174	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
1267753007175	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1267753007176	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
1267753007177	D-subunit interface [polypeptide binding]; other site
1267753007178	Iron-sulfur protein interface; other site
1267753007179	proximal quinone binding site [chemical binding]; other site
1267753007180	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
1267753007181	Iron-sulfur protein interface; other site
1267753007182	proximal quinone binding site [chemical binding]; other site
1267753007183	C-subunit interface; other site
1267753007184	distal quinone binding site; other site
1267753007185	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
1267753007186	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1267753007187	multidrug efflux system protein; Provisional; Region: PRK11431
1267753007188	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1267753007189	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753007190	DNA binding residues [nucleotide binding]
1267753007191	dimerization interface [polypeptide binding]; other site
1267753007192	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
1267753007193	Predicted small secreted protein [Function unknown]; Region: COG5510
1267753007194	elongation factor P; Validated; Region: PRK00529
1267753007195	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1267753007196	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1267753007197	RNA binding site [nucleotide binding]; other site
1267753007198	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1267753007199	RNA binding site [nucleotide binding]; other site
1267753007200	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1267753007201	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753007202	FeS/SAM binding site; other site
1267753007203	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
1267753007204	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1267753007205	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1267753007206	ring oligomerisation interface [polypeptide binding]; other site
1267753007207	ATP/Mg binding site [chemical binding]; other site
1267753007208	stacking interactions; other site
1267753007209	hinge regions; other site
1267753007210	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1267753007211	oligomerisation interface [polypeptide binding]; other site
1267753007212	mobile loop; other site
1267753007213	roof hairpin; other site
1267753007214	putative transporter; Provisional; Region: PRK11021
1267753007215	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
1267753007216	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1267753007217	Aspartase; Region: Aspartase; cd01357
1267753007218	active sites [active]
1267753007219	tetramer interface [polypeptide binding]; other site
1267753007220	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1267753007221	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1267753007222	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
1267753007223	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
1267753007224	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1267753007225	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1267753007226	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1267753007227	DsbD alpha interface [polypeptide binding]; other site
1267753007228	catalytic residues [active]
1267753007229	putative transcriptional regulator; Provisional; Region: PRK11640
1267753007230	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753007231	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1267753007232	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1267753007233	active site
1267753007234	SdiA-regulated; Region: SdiA-regulated; pfam06977
1267753007235	SdiA-regulated; Region: SdiA-regulated; cd09971
1267753007236	putative active site [active]
1267753007237	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753007238	fimbriae biosynthesis regulatory protein; Provisional; Region: PRK15215
1267753007239	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753007240	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753007241	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753007242	Coenzyme A binding pocket [chemical binding]; other site
1267753007243	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1267753007244	AraC family transcriptional regulator; Provisional; Region: PRK15186
1267753007245	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753007246	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1267753007247	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753007248	DNA binding residues [nucleotide binding]
1267753007249	dimerization interface [polypeptide binding]; other site
1267753007250	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
1267753007251	SdiA-regulated; Region: SdiA-regulated; cd09971
1267753007252	putative active site [active]
1267753007253	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
1267753007254	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
1267753007255	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
1267753007256	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1267753007257	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1267753007258	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1267753007259	putative [Fe4-S4] binding site [ion binding]; other site
1267753007260	putative molybdopterin cofactor binding site [chemical binding]; other site
1267753007261	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1267753007262	putative molybdopterin cofactor binding site; other site
1267753007263	potential frameshift: common BLAST hit: gi|194734757|ref|YP_002117239.1| sensory histidine kinase DcuS
1267753007264	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
1267753007265	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753007266	active site
1267753007267	phosphorylation site [posttranslational modification]
1267753007268	intermolecular recognition site; other site
1267753007269	dimerization interface [polypeptide binding]; other site
1267753007270	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1267753007271	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1267753007272	fumarate hydratase; Provisional; Region: PRK15389
1267753007273	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
1267753007274	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1267753007275	melibiose:sodium symporter; Provisional; Region: PRK10429
1267753007276	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1267753007277	alpha-galactosidase; Provisional; Region: PRK15076
1267753007278	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
1267753007279	NAD binding site [chemical binding]; other site
1267753007280	sugar binding site [chemical binding]; other site
1267753007281	divalent metal binding site [ion binding]; other site
1267753007282	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
1267753007283	dimer interface [polypeptide binding]; other site
1267753007284	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
1267753007285	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753007286	arginine decarboxylase; Provisional; Region: PRK15029
1267753007287	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1267753007288	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1267753007289	homodimer interface [polypeptide binding]; other site
1267753007290	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753007291	catalytic residue [active]
1267753007292	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1267753007293	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
1267753007294	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753007295	arginine:agmatin antiporter; Provisional; Region: PRK10644
1267753007296	putative metal dependent hydrolase; Provisional; Region: PRK11598
1267753007297	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1267753007298	Sulfatase; Region: Sulfatase; pfam00884
1267753007299	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
1267753007300	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753007301	active site
1267753007302	phosphorylation site [posttranslational modification]
1267753007303	intermolecular recognition site; other site
1267753007304	dimerization interface [polypeptide binding]; other site
1267753007305	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753007306	DNA binding site [nucleotide binding]
1267753007307	sensor protein BasS/PmrB; Provisional; Region: PRK10755
1267753007308	HAMP domain; Region: HAMP; pfam00672
1267753007309	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753007310	dimer interface [polypeptide binding]; other site
1267753007311	phosphorylation site [posttranslational modification]
1267753007312	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753007313	ATP binding site [chemical binding]; other site
1267753007314	Mg2+ binding site [ion binding]; other site
1267753007315	G-X-G motif; other site
1267753007316	proline/glycine betaine transporter; Provisional; Region: PRK10642
1267753007317	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753007318	putative substrate translocation pore; other site
1267753007319	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
1267753007320	hypothetical protein; Provisional; Region: PRK10220
1267753007321	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1267753007322	PhnA protein; Region: PhnA; pfam03831
1267753007323	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1267753007324	dimer interface [polypeptide binding]; other site
1267753007325	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1267753007326	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753007327	Coenzyme A binding pocket [chemical binding]; other site
1267753007328	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
1267753007329	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753007330	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753007331	molybdopterin cofactor binding site; other site
1267753007332	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1267753007333	molybdopterin cofactor binding site; other site
1267753007334	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1267753007335	Sel1-like repeats; Region: SEL1; smart00671
1267753007336	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
1267753007337	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1267753007338	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1267753007339	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
1267753007340	heme lyase subunit NrfE; Provisional; Region: PRK10369
1267753007341	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
1267753007342	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
1267753007343	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
1267753007344	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
1267753007345	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
1267753007346	acetyl-CoA synthetase; Provisional; Region: PRK00174
1267753007347	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1267753007348	active site
1267753007349	CoA binding site [chemical binding]; other site
1267753007350	acyl-activating enzyme (AAE) consensus motif; other site
1267753007351	AMP binding site [chemical binding]; other site
1267753007352	acetate binding site [chemical binding]; other site
1267753007353	Predicted membrane protein [Function unknown]; Region: COG3162
1267753007354	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1267753007355	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1267753007356	Na binding site [ion binding]; other site
1267753007357	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1267753007358	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
1267753007359	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753007360	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753007361	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1267753007362	putative dimerization interface [polypeptide binding]; other site
1267753007363	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
1267753007364	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1267753007365	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1267753007366	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
1267753007367	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
1267753007368	putative C-terminal domain interface [polypeptide binding]; other site
1267753007369	putative GSH binding site (G-site) [chemical binding]; other site
1267753007370	putative dimer interface [polypeptide binding]; other site
1267753007371	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
1267753007372	putative N-terminal domain interface [polypeptide binding]; other site
1267753007373	putative dimer interface [polypeptide binding]; other site
1267753007374	putative substrate binding pocket (H-site) [chemical binding]; other site
1267753007375	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
1267753007376	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
1267753007377	DNA binding residues [nucleotide binding]
1267753007378	dimer interface [polypeptide binding]; other site
1267753007379	[2Fe-2S] cluster binding site [ion binding]; other site
1267753007380	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
1267753007381	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753007382	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
1267753007383	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
1267753007384	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753007385	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1267753007386	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753007387	Walker A/P-loop; other site
1267753007388	ATP binding site [chemical binding]; other site
1267753007389	Q-loop/lid; other site
1267753007390	ABC transporter signature motif; other site
1267753007391	Walker B; other site
1267753007392	D-loop; other site
1267753007393	H-loop/switch region; other site
1267753007394	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1267753007395	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007396	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007397	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007398	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007399	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007400	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1267753007401	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1267753007402	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007403	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1267753007404	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007405	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1267753007406	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1267753007407	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007408	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1267753007409	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1267753007410	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007411	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1267753007412	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007413	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1267753007414	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1267753007415	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007416	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1267753007417	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1267753007418	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007419	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1267753007420	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007421	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007422	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
1267753007423	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007424	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007425	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007426	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007427	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007428	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007429	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1267753007430	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007431	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
1267753007432	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007433	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007434	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753007435	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1267753007436	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753007437	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753007438	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1267753007439	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
1267753007440	hypothetical protein; Validated; Region: PRK09039
1267753007441	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1267753007442	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1267753007443	dimer interface [polypeptide binding]; other site
1267753007444	ssDNA binding site [nucleotide binding]; other site
1267753007445	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1267753007446	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1267753007447	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1267753007448	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1267753007449	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1267753007450	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1267753007451	Uncharacterized conserved protein [Function unknown]; Region: COG0432
1267753007452	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753007453	active site
1267753007454	motif I; other site
1267753007455	motif II; other site
1267753007456	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
1267753007457	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753007458	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753007459	homodimer interface [polypeptide binding]; other site
1267753007460	catalytic residue [active]
1267753007461	alanine racemase; Reviewed; Region: alr; PRK00053
1267753007462	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
1267753007463	active site
1267753007464	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1267753007465	substrate binding site [chemical binding]; other site
1267753007466	catalytic residues [active]
1267753007467	dimer interface [polypeptide binding]; other site
1267753007468	replicative DNA helicase; Provisional; Region: PRK08006
1267753007469	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1267753007470	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1267753007471	Walker A motif; other site
1267753007472	ATP binding site [chemical binding]; other site
1267753007473	Walker B motif; other site
1267753007474	DNA binding loops [nucleotide binding]
1267753007475	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
1267753007476	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1267753007477	NADP binding site [chemical binding]; other site
1267753007478	dimer interface [polypeptide binding]; other site
1267753007479	phage shock protein G; Reviewed; Region: pspG; PRK09459
1267753007480	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
1267753007481	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1267753007482	FMN binding site [chemical binding]; other site
1267753007483	active site
1267753007484	catalytic residues [active]
1267753007485	substrate binding site [chemical binding]; other site
1267753007486	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
1267753007487	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1267753007488	metal binding site 2 [ion binding]; metal-binding site
1267753007489	putative DNA binding helix; other site
1267753007490	metal binding site 1 [ion binding]; metal-binding site
1267753007491	dimer interface [polypeptide binding]; other site
1267753007492	structural Zn2+ binding site [ion binding]; other site
1267753007493	hypothetical protein; Provisional; Region: PRK10428
1267753007494	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
1267753007495	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
1267753007496	LexA repressor; Validated; Region: PRK00215
1267753007497	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1267753007498	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1267753007499	Catalytic site [active]
1267753007500	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1267753007501	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
1267753007502	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
1267753007503	putative acyl-acceptor binding pocket; other site
1267753007504	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
1267753007505	UbiA prenyltransferase family; Region: UbiA; pfam01040
1267753007506	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
1267753007507	maltose regulon periplasmic protein; Provisional; Region: PRK10564
1267753007508	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
1267753007509	trimer interface; other site
1267753007510	sugar binding site [chemical binding]; other site
1267753007511	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
1267753007512	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1267753007513	Walker A/P-loop; other site
1267753007514	ATP binding site [chemical binding]; other site
1267753007515	Q-loop/lid; other site
1267753007516	ABC transporter signature motif; other site
1267753007517	Walker B; other site
1267753007518	D-loop; other site
1267753007519	H-loop/switch region; other site
1267753007520	TOBE domain; Region: TOBE_2; pfam08402
1267753007521	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
1267753007522	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1267753007523	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1267753007524	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753007525	dimer interface [polypeptide binding]; other site
1267753007526	conserved gate region; other site
1267753007527	putative PBP binding loops; other site
1267753007528	ABC-ATPase subunit interface; other site
1267753007529	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1267753007530	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753007531	dimer interface [polypeptide binding]; other site
1267753007532	conserved gate region; other site
1267753007533	putative PBP binding loops; other site
1267753007534	ABC-ATPase subunit interface; other site
1267753007535	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1267753007536	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753007537	Predicted membrane protein [Function unknown]; Region: COG3223
1267753007538	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
1267753007539	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
1267753007540	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
1267753007541	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1267753007542	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1267753007543	active site
1267753007544	dimer interface [polypeptide binding]; other site
1267753007545	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1267753007546	dimer interface [polypeptide binding]; other site
1267753007547	active site
1267753007548	aspartate kinase III; Validated; Region: PRK09084
1267753007549	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1267753007550	nucleotide binding site [chemical binding]; other site
1267753007551	substrate binding site [chemical binding]; other site
1267753007552	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1267753007553	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
1267753007554	dimer interface [polypeptide binding]; other site
1267753007555	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1267753007556	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
1267753007557	active site
1267753007558	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1267753007559	phosphate binding site [ion binding]; other site
1267753007560	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1267753007561	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753007562	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753007563	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1267753007564	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753007565	hypothetical protein; Provisional; Region: PRK10515
1267753007566	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
1267753007567	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1267753007568	RNA binding surface [nucleotide binding]; other site
1267753007569	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1267753007570	probable active site [active]
1267753007571	potential frameshift: common BLAST hit: gi|409247886|ref|YP_006888578.1| Uncharacterized protein yaiL
1267753007572	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1267753007573	active site pocket [active]
1267753007574	oxyanion hole [active]
1267753007575	catalytic triad [active]
1267753007576	active site nucleophile [active]
1267753007577	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1267753007578	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1267753007579	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
1267753007580	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1267753007581	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1267753007582	substrate binding pocket [chemical binding]; other site
1267753007583	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
1267753007584	B12 binding site [chemical binding]; other site
1267753007585	cobalt ligand [ion binding]; other site
1267753007586	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1267753007587	transcriptional repressor IclR; Provisional; Region: PRK11569
1267753007588	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1267753007589	Bacterial transcriptional regulator; Region: IclR; pfam01614
1267753007590	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
1267753007591	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
1267753007592	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
1267753007593	isocitrate lyase; Provisional; Region: PRK15063
1267753007594	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1267753007595	tetramer interface [polypeptide binding]; other site
1267753007596	active site
1267753007597	Mg2+/Mn2+ binding site [ion binding]; other site
1267753007598	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1267753007599	malate synthase A; Region: malate_syn_A; TIGR01344
1267753007600	active site
1267753007601	homoserine O-succinyltransferase; Provisional; Region: PRK05368
1267753007602	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1267753007603	proposed active site lysine [active]
1267753007604	conserved cys residue [active]
1267753007605	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1267753007606	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753007607	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1267753007608	Coenzyme A binding pocket [chemical binding]; other site
1267753007609	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1267753007610	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1267753007611	purine monophosphate binding site [chemical binding]; other site
1267753007612	dimer interface [polypeptide binding]; other site
1267753007613	putative catalytic residues [active]
1267753007614	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1267753007615	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1267753007616	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1267753007617	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1267753007618	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1267753007619	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
1267753007620	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753007621	active site
1267753007622	phosphorylation site [posttranslational modification]
1267753007623	intermolecular recognition site; other site
1267753007624	dimerization interface [polypeptide binding]; other site
1267753007625	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753007626	Walker A motif; other site
1267753007627	ATP binding site [chemical binding]; other site
1267753007628	Walker B motif; other site
1267753007629	arginine finger; other site
1267753007630	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1267753007631	sensor protein ZraS; Provisional; Region: PRK10364
1267753007632	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753007633	dimer interface [polypeptide binding]; other site
1267753007634	phosphorylation site [posttranslational modification]
1267753007635	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753007636	ATP binding site [chemical binding]; other site
1267753007637	Mg2+ binding site [ion binding]; other site
1267753007638	G-X-G motif; other site
1267753007639	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1267753007640	dimer interface [polypeptide binding]; other site
1267753007641	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
1267753007642	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1267753007643	IHF dimer interface [polypeptide binding]; other site
1267753007644	IHF - DNA interface [nucleotide binding]; other site
1267753007645	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
1267753007646	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
1267753007647	Active_site [active]
1267753007648	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1267753007649	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1267753007650	substrate binding site [chemical binding]; other site
1267753007651	active site
1267753007652	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
1267753007653	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
1267753007654	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
1267753007655	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
1267753007656	putative NADH binding site [chemical binding]; other site
1267753007657	putative active site [active]
1267753007658	nudix motif; other site
1267753007659	putative metal binding site [ion binding]; other site
1267753007660	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
1267753007661	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
1267753007662	ThiC-associated domain; Region: ThiC-associated; pfam13667
1267753007663	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
1267753007664	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1267753007665	thiamine phosphate binding site [chemical binding]; other site
1267753007666	active site
1267753007667	pyrophosphate binding site [ion binding]; other site
1267753007668	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1267753007669	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
1267753007670	ATP binding site [chemical binding]; other site
1267753007671	substrate interface [chemical binding]; other site
1267753007672	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1267753007673	thiS-thiF/thiG interaction site; other site
1267753007674	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1267753007675	ThiS interaction site; other site
1267753007676	putative active site [active]
1267753007677	tetramer interface [polypeptide binding]; other site
1267753007678	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1267753007679	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753007680	FeS/SAM binding site; other site
1267753007681	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1267753007682	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1267753007683	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1267753007684	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1267753007685	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1267753007686	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1267753007687	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1267753007688	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1267753007689	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1267753007690	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1267753007691	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1267753007692	DNA binding site [nucleotide binding]
1267753007693	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1267753007694	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1267753007695	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1267753007696	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1267753007697	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1267753007698	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
1267753007699	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1267753007700	RPB3 interaction site [polypeptide binding]; other site
1267753007701	RPB1 interaction site [polypeptide binding]; other site
1267753007702	RPB11 interaction site [polypeptide binding]; other site
1267753007703	RPB10 interaction site [polypeptide binding]; other site
1267753007704	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1267753007705	core dimer interface [polypeptide binding]; other site
1267753007706	peripheral dimer interface [polypeptide binding]; other site
1267753007707	L10 interface [polypeptide binding]; other site
1267753007708	L11 interface [polypeptide binding]; other site
1267753007709	putative EF-Tu interaction site [polypeptide binding]; other site
1267753007710	putative EF-G interaction site [polypeptide binding]; other site
1267753007711	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1267753007712	23S rRNA interface [nucleotide binding]; other site
1267753007713	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1267753007714	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1267753007715	mRNA/rRNA interface [nucleotide binding]; other site
1267753007716	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1267753007717	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1267753007718	23S rRNA interface [nucleotide binding]; other site
1267753007719	L7/L12 interface [polypeptide binding]; other site
1267753007720	putative thiostrepton binding site; other site
1267753007721	L25 interface [polypeptide binding]; other site
1267753007722	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1267753007723	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1267753007724	putative homodimer interface [polypeptide binding]; other site
1267753007725	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1267753007726	heterodimer interface [polypeptide binding]; other site
1267753007727	homodimer interface [polypeptide binding]; other site
1267753007728	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
1267753007729	elongation factor Tu; Reviewed; Region: PRK00049
1267753007730	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1267753007731	G1 box; other site
1267753007732	GEF interaction site [polypeptide binding]; other site
1267753007733	GTP/Mg2+ binding site [chemical binding]; other site
1267753007734	Switch I region; other site
1267753007735	G2 box; other site
1267753007736	G3 box; other site
1267753007737	Switch II region; other site
1267753007738	G4 box; other site
1267753007739	G5 box; other site
1267753007740	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1267753007741	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1267753007742	Antibiotic Binding Site [chemical binding]; other site
1267753007743	pantothenate kinase; Provisional; Region: PRK05439
1267753007744	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
1267753007745	ATP-binding site [chemical binding]; other site
1267753007746	CoA-binding site [chemical binding]; other site
1267753007747	Mg2+-binding site [ion binding]; other site
1267753007748	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1267753007749	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1267753007750	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1267753007751	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1267753007752	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1267753007753	FAD binding domain; Region: FAD_binding_4; pfam01565
1267753007754	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1267753007755	glutamate racemase; Provisional; Region: PRK00865
1267753007756	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
1267753007757	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1267753007758	N-terminal plug; other site
1267753007759	ligand-binding site [chemical binding]; other site
1267753007760	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
1267753007761	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
1267753007762	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753007763	S-adenosylmethionine binding site [chemical binding]; other site
1267753007764	hypothetical protein; Provisional; Region: PRK11056
1267753007765	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
1267753007766	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753007767	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
1267753007768	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753007769	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1267753007770	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1267753007771	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753007772	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1267753007773	dimerization interface [polypeptide binding]; other site
1267753007774	argininosuccinate lyase; Provisional; Region: PRK04833
1267753007775	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1267753007776	active sites [active]
1267753007777	tetramer interface [polypeptide binding]; other site
1267753007778	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
1267753007779	nucleotide binding site [chemical binding]; other site
1267753007780	N-acetyl-L-glutamate binding site [chemical binding]; other site
1267753007781	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1267753007782	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1267753007783	acetylornithine deacetylase; Provisional; Region: PRK05111
1267753007784	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
1267753007785	metal binding site [ion binding]; metal-binding site
1267753007786	putative dimer interface [polypeptide binding]; other site
1267753007787	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
1267753007788	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
1267753007789	hypothetical protein; Provisional; Region: PRK10649
1267753007790	Sulfatase; Region: Sulfatase; pfam00884
1267753007791	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1267753007792	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753007793	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1267753007794	active site
1267753007795	P-loop; other site
1267753007796	phosphorylation site [posttranslational modification]
1267753007797	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753007798	FeS/SAM binding site; other site
1267753007799	pyruvate formate lyase II activase; Provisional; Region: PRK10076
1267753007800	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
1267753007801	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
1267753007802	dimer interface [polypeptide binding]; other site
1267753007803	active site
1267753007804	glycine loop; other site
1267753007805	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1267753007806	active site
1267753007807	P-loop; other site
1267753007808	phosphorylation site [posttranslational modification]
1267753007809	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
1267753007810	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1267753007811	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1267753007812	dimerization domain swap beta strand [polypeptide binding]; other site
1267753007813	regulatory protein interface [polypeptide binding]; other site
1267753007814	active site
1267753007815	regulatory phosphorylation site [posttranslational modification]; other site
1267753007816	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1267753007817	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1267753007818	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1267753007819	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1267753007820	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753007821	active site
1267753007822	phosphorylation site [posttranslational modification]
1267753007823	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1267753007824	active site
1267753007825	intersubunit interactions; other site
1267753007826	catalytic residue [active]
1267753007827	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1267753007828	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1267753007829	dimer interface [polypeptide binding]; other site
1267753007830	active site
1267753007831	metal binding site [ion binding]; metal-binding site
1267753007832	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1267753007833	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1267753007834	heme binding site [chemical binding]; other site
1267753007835	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1267753007836	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1267753007837	FAD binding site [chemical binding]; other site
1267753007838	potential frameshift: common BLAST hit: gi|378961676|ref|YP_005219162.1| 5'-nucleotidase
1267753007839	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
1267753007840	mechanosensitive channel MscS; Provisional; Region: PRK10334
1267753007841	Conserved TM helix; Region: TM_helix; pfam05552
1267753007842	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1267753007843	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
1267753007844	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1267753007845	putative catalytic residues [active]
1267753007846	putative nucleotide binding site [chemical binding]; other site
1267753007847	putative aspartate binding site [chemical binding]; other site
1267753007848	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
1267753007849	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1267753007850	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1267753007851	cystathionine gamma-synthase; Provisional; Region: PRK08045
1267753007852	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1267753007853	homodimer interface [polypeptide binding]; other site
1267753007854	substrate-cofactor binding pocket; other site
1267753007855	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753007856	catalytic residue [active]
1267753007857	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
1267753007858	dimerization interface [polypeptide binding]; other site
1267753007859	DNA binding site [nucleotide binding]
1267753007860	corepressor binding sites; other site
1267753007861	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1267753007862	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
1267753007863	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1267753007864	primosome assembly protein PriA; Validated; Region: PRK05580
1267753007865	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753007866	ATP binding site [chemical binding]; other site
1267753007867	putative Mg++ binding site [ion binding]; other site
1267753007868	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1267753007869	ATP-binding site [chemical binding]; other site
1267753007870	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753007871	DNA binding site [nucleotide binding]
1267753007872	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
1267753007873	domain linker motif; other site
1267753007874	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
1267753007875	dimerization interface [polypeptide binding]; other site
1267753007876	ligand binding site [chemical binding]; other site
1267753007877	essential cell division protein FtsN; Provisional; Region: PRK10927
1267753007878	cell division protein FtsN; Provisional; Region: PRK12757
1267753007879	Sporulation related domain; Region: SPOR; cl10051
1267753007880	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1267753007881	active site
1267753007882	HslU subunit interaction site [polypeptide binding]; other site
1267753007883	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1267753007884	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753007885	Walker A motif; other site
1267753007886	ATP binding site [chemical binding]; other site
1267753007887	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1267753007888	Walker B motif; other site
1267753007889	arginine finger; other site
1267753007890	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1267753007891	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
1267753007892	UbiA prenyltransferase family; Region: UbiA; pfam01040
1267753007893	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
1267753007894	septal ring assembly protein ZapB; Provisional; Region: PRK15422
1267753007895	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
1267753007896	amphipathic channel; other site
1267753007897	Asn-Pro-Ala signature motifs; other site
1267753007898	glycerol kinase; Provisional; Region: glpK; PRK00047
1267753007899	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1267753007900	N- and C-terminal domain interface [polypeptide binding]; other site
1267753007901	active site
1267753007902	MgATP binding site [chemical binding]; other site
1267753007903	catalytic site [active]
1267753007904	metal binding site [ion binding]; metal-binding site
1267753007905	glycerol binding site [chemical binding]; other site
1267753007906	homotetramer interface [polypeptide binding]; other site
1267753007907	homodimer interface [polypeptide binding]; other site
1267753007908	FBP binding site [chemical binding]; other site
1267753007909	protein IIAGlc interface [polypeptide binding]; other site
1267753007910	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1267753007911	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1267753007912	putative active site [active]
1267753007913	ferredoxin-NADP reductase; Provisional; Region: PRK10926
1267753007914	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
1267753007915	FAD binding pocket [chemical binding]; other site
1267753007916	FAD binding motif [chemical binding]; other site
1267753007917	phosphate binding motif [ion binding]; other site
1267753007918	beta-alpha-beta structure motif; other site
1267753007919	NAD binding pocket [chemical binding]; other site
1267753007920	Predicted membrane protein [Function unknown]; Region: COG3152
1267753007921	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
1267753007922	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1267753007923	triosephosphate isomerase; Provisional; Region: PRK14567
1267753007924	substrate binding site [chemical binding]; other site
1267753007925	dimer interface [polypeptide binding]; other site
1267753007926	catalytic triad [active]
1267753007927	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1267753007928	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1267753007929	substrate binding site [chemical binding]; other site
1267753007930	hexamer interface [polypeptide binding]; other site
1267753007931	metal binding site [ion binding]; metal-binding site
1267753007932	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
1267753007933	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
1267753007934	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
1267753007935	putative active site; other site
1267753007936	catalytic residue [active]
1267753007937	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
1267753007938	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
1267753007939	ligand binding site [chemical binding]; other site
1267753007940	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1267753007941	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1267753007942	TM-ABC transporter signature motif; other site
1267753007943	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1267753007944	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1267753007945	TM-ABC transporter signature motif; other site
1267753007946	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
1267753007947	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1267753007948	Walker A/P-loop; other site
1267753007949	ATP binding site [chemical binding]; other site
1267753007950	Q-loop/lid; other site
1267753007951	ABC transporter signature motif; other site
1267753007952	Walker B; other site
1267753007953	D-loop; other site
1267753007954	H-loop/switch region; other site
1267753007955	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1267753007956	transcriptional regulator LsrR; Provisional; Region: PRK15418
1267753007957	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1267753007958	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1267753007959	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
1267753007960	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
1267753007961	putative N- and C-terminal domain interface [polypeptide binding]; other site
1267753007962	putative active site [active]
1267753007963	putative MgATP binding site [chemical binding]; other site
1267753007964	catalytic site [active]
1267753007965	metal binding site [ion binding]; metal-binding site
1267753007966	putative carbohydrate binding site [chemical binding]; other site
1267753007967	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1267753007968	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1267753007969	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753007970	DNA-binding site [nucleotide binding]; DNA binding site
1267753007971	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
1267753007972	UTRA domain; Region: UTRA; pfam07702
1267753007973	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
1267753007974	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753007975	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1267753007976	putative substrate binding site [chemical binding]; other site
1267753007977	putative ATP binding site [chemical binding]; other site
1267753007978	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1267753007979	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1267753007980	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
1267753007981	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1267753007982	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753007983	substrate binding pocket [chemical binding]; other site
1267753007984	membrane-bound complex binding site; other site
1267753007985	hinge residues; other site
1267753007986	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1267753007987	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1267753007988	active site
1267753007989	ADP/pyrophosphate binding site [chemical binding]; other site
1267753007990	dimerization interface [polypeptide binding]; other site
1267753007991	allosteric effector site; other site
1267753007992	fructose-1,6-bisphosphate binding site; other site
1267753007993	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
1267753007994	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1267753007995	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
1267753007996	dimer interface [polypeptide binding]; other site
1267753007997	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
1267753007998	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753007999	active site
1267753008000	intermolecular recognition site; other site
1267753008001	dimerization interface [polypeptide binding]; other site
1267753008002	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753008003	DNA binding site [nucleotide binding]
1267753008004	two-component sensor protein; Provisional; Region: cpxA; PRK09470
1267753008005	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753008006	dimerization interface [polypeptide binding]; other site
1267753008007	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753008008	dimer interface [polypeptide binding]; other site
1267753008009	phosphorylation site [posttranslational modification]
1267753008010	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753008011	ATP binding site [chemical binding]; other site
1267753008012	Mg2+ binding site [ion binding]; other site
1267753008013	G-X-G motif; other site
1267753008014	SnoaL-like domain; Region: SnoaL_2; pfam12680
1267753008015	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
1267753008016	MOSC domain; Region: MOSC; pfam03473
1267753008017	3-alpha domain; Region: 3-alpha; pfam03475
1267753008018	superoxide dismutase; Provisional; Region: PRK10925
1267753008019	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1267753008020	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1267753008021	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1267753008022	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
1267753008023	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
1267753008024	DctM-like transporters; Region: DctM; pfam06808
1267753008025	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
1267753008026	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
1267753008027	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
1267753008028	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
1267753008029	transcriptional activator RhaR; Provisional; Region: PRK13502
1267753008030	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1267753008031	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753008032	transcriptional activator RhaS; Provisional; Region: PRK13503
1267753008033	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1267753008034	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753008035	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753008036	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
1267753008037	N- and C-terminal domain interface [polypeptide binding]; other site
1267753008038	active site
1267753008039	putative catalytic site [active]
1267753008040	metal binding site [ion binding]; metal-binding site
1267753008041	ATP binding site [chemical binding]; other site
1267753008042	rhamnulokinase; Provisional; Region: rhaB; PRK10640
1267753008043	carbohydrate binding site [chemical binding]; other site
1267753008044	L-rhamnose isomerase; Provisional; Region: PRK01076
1267753008045	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
1267753008046	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1267753008047	intersubunit interface [polypeptide binding]; other site
1267753008048	active site
1267753008049	Zn2+ binding site [ion binding]; other site
1267753008050	lactaldehyde reductase; Region: lactal_redase; TIGR02638
1267753008051	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1267753008052	dimer interface [polypeptide binding]; other site
1267753008053	active site
1267753008054	metal binding site [ion binding]; metal-binding site
1267753008055	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
1267753008056	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753008057	non-specific DNA binding site [nucleotide binding]; other site
1267753008058	salt bridge; other site
1267753008059	sequence-specific DNA binding site [nucleotide binding]; other site
1267753008060	Cupin domain; Region: Cupin_2; cl17218
1267753008061	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1267753008062	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1267753008063	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
1267753008064	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1267753008065	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753008066	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1267753008067	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
1267753008068	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
1267753008069	molybdopterin cofactor binding site; other site
1267753008070	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
1267753008071	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
1267753008072	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
1267753008073	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1267753008074	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
1267753008075	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
1267753008076	Predicted transcriptional regulator [Transcription]; Region: COG2944
1267753008077	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753008078	non-specific DNA binding site [nucleotide binding]; other site
1267753008079	salt bridge; other site
1267753008080	sequence-specific DNA binding site [nucleotide binding]; other site
1267753008081	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
1267753008082	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1267753008083	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1267753008084	substrate binding pocket [chemical binding]; other site
1267753008085	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
1267753008086	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753008087	non-specific DNA binding site [nucleotide binding]; other site
1267753008088	salt bridge; other site
1267753008089	sequence-specific DNA binding site [nucleotide binding]; other site
1267753008090	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753008091	Coenzyme A binding pocket [chemical binding]; other site
1267753008092	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1267753008093	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1267753008094	putative active site [active]
1267753008095	dimerization interface [polypeptide binding]; other site
1267753008096	putative tRNAtyr binding site [nucleotide binding]; other site
1267753008097	hypothetical protein; Reviewed; Region: PRK01637
1267753008098	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1267753008099	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753008100	motif II; other site
1267753008101	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753008102	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1267753008103	putative DNA binding site [nucleotide binding]; other site
1267753008104	putative Zn2+ binding site [ion binding]; other site
1267753008105	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753008106	potential frameshift: common BLAST hit: gi|379703265|ref|YP_005244993.1| putative sugar kinase
1267753008107	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
1267753008108	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1267753008109	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
1267753008110	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
1267753008111	dimerization interface [polypeptide binding]; other site
1267753008112	putative active cleft [active]
1267753008113	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
1267753008114	active site
1267753008115	catalytic residues [active]
1267753008116	alpha-glucosidase; Provisional; Region: PRK10426
1267753008117	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1267753008118	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
1267753008119	putative active site [active]
1267753008120	putative catalytic site [active]
1267753008121	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
1267753008122	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1267753008123	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
1267753008124	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008125	putative substrate translocation pore; other site
1267753008126	outer membrane porin L; Provisional; Region: ompL; PRK09980
1267753008127	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
1267753008128	Leucine-rich repeats; other site
1267753008129	Substrate binding site [chemical binding]; other site
1267753008130	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
1267753008131	Sulfatase; Region: Sulfatase; cl17466
1267753008132	coproporphyrinogen III oxidase; Validated; Region: PRK08208
1267753008133	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753008134	FeS/SAM binding site; other site
1267753008135	HemN C-terminal domain; Region: HemN_C; pfam06969
1267753008136	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753008137	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1267753008138	active site
1267753008139	motif I; other site
1267753008140	motif II; other site
1267753008141	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753008142	GTP-binding protein; Provisional; Region: PRK10218
1267753008143	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1267753008144	G1 box; other site
1267753008145	putative GEF interaction site [polypeptide binding]; other site
1267753008146	GTP/Mg2+ binding site [chemical binding]; other site
1267753008147	Switch I region; other site
1267753008148	G2 box; other site
1267753008149	G3 box; other site
1267753008150	Switch II region; other site
1267753008151	G4 box; other site
1267753008152	G5 box; other site
1267753008153	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1267753008154	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1267753008155	glutamine synthetase; Provisional; Region: glnA; PRK09469
1267753008156	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1267753008157	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1267753008158	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
1267753008159	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1267753008160	putative active site [active]
1267753008161	heme pocket [chemical binding]; other site
1267753008162	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753008163	dimer interface [polypeptide binding]; other site
1267753008164	phosphorylation site [posttranslational modification]
1267753008165	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753008166	ATP binding site [chemical binding]; other site
1267753008167	Mg2+ binding site [ion binding]; other site
1267753008168	G-X-G motif; other site
1267753008169	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
1267753008170	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753008171	active site
1267753008172	phosphorylation site [posttranslational modification]
1267753008173	intermolecular recognition site; other site
1267753008174	dimerization interface [polypeptide binding]; other site
1267753008175	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753008176	Walker A motif; other site
1267753008177	ATP binding site [chemical binding]; other site
1267753008178	Walker B motif; other site
1267753008179	arginine finger; other site
1267753008180	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1267753008181	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1267753008182	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753008183	FeS/SAM binding site; other site
1267753008184	HemN C-terminal domain; Region: HemN_C; pfam06969
1267753008185	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
1267753008186	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1267753008187	G1 box; other site
1267753008188	GTP/Mg2+ binding site [chemical binding]; other site
1267753008189	Switch I region; other site
1267753008190	G2 box; other site
1267753008191	G3 box; other site
1267753008192	Switch II region; other site
1267753008193	G4 box; other site
1267753008194	G5 box; other site
1267753008195	DNA polymerase I; Provisional; Region: PRK05755
1267753008196	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1267753008197	active site
1267753008198	metal binding site 1 [ion binding]; metal-binding site
1267753008199	putative 5' ssDNA interaction site; other site
1267753008200	metal binding site 3; metal-binding site
1267753008201	metal binding site 2 [ion binding]; metal-binding site
1267753008202	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1267753008203	putative DNA binding site [nucleotide binding]; other site
1267753008204	putative metal binding site [ion binding]; other site
1267753008205	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1267753008206	active site
1267753008207	catalytic site [active]
1267753008208	substrate binding site [chemical binding]; other site
1267753008209	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1267753008210	active site
1267753008211	DNA binding site [nucleotide binding]
1267753008212	catalytic site [active]
1267753008213	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1267753008214	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
1267753008215	putative acyl-acceptor binding pocket; other site
1267753008216	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1267753008217	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1267753008218	catalytic residues [active]
1267753008219	hinge region; other site
1267753008220	alpha helical domain; other site
1267753008221	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
1267753008222	serine/threonine protein kinase; Provisional; Region: PRK11768
1267753008223	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
1267753008224	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1267753008225	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1267753008226	GTP binding site; other site
1267753008227	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1267753008228	Walker A motif; other site
1267753008229	potential RNA of insufficient length (23S ribosomal RNA)
1267753008230	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
1267753008231	potassium transporter; Provisional; Region: PRK10750
1267753008232	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1267753008233	hypothetical protein; Provisional; Region: PRK11568
1267753008234	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1267753008235	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1267753008236	proline dipeptidase; Provisional; Region: PRK13607
1267753008237	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1267753008238	active site
1267753008239	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
1267753008240	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1267753008241	substrate binding site [chemical binding]; other site
1267753008242	oxyanion hole (OAH) forming residues; other site
1267753008243	trimer interface [polypeptide binding]; other site
1267753008244	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1267753008245	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1267753008246	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1267753008247	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
1267753008248	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1267753008249	dimer interface [polypeptide binding]; other site
1267753008250	active site
1267753008251	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1267753008252	FMN reductase; Validated; Region: fre; PRK08051
1267753008253	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
1267753008254	FAD binding pocket [chemical binding]; other site
1267753008255	FAD binding motif [chemical binding]; other site
1267753008256	phosphate binding motif [ion binding]; other site
1267753008257	beta-alpha-beta structure motif; other site
1267753008258	NAD binding pocket [chemical binding]; other site
1267753008259	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
1267753008260	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
1267753008261	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
1267753008262	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
1267753008263	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1267753008264	active site
1267753008265	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
1267753008266	sec-independent translocase; Provisional; Region: PRK01770
1267753008267	sec-independent translocase; Provisional; Region: tatB; PRK00404
1267753008268	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
1267753008269	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
1267753008270	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1267753008271	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
1267753008272	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1267753008273	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1267753008274	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753008275	S-adenosylmethionine binding site [chemical binding]; other site
1267753008276	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
1267753008277	DNA recombination protein RmuC; Provisional; Region: PRK10361
1267753008278	RmuC family; Region: RmuC; pfam02646
1267753008279	uridine phosphorylase; Provisional; Region: PRK11178
1267753008280	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
1267753008281	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
1267753008282	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1267753008283	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753008284	FeS/SAM binding site; other site
1267753008285	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1267753008286	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1267753008287	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1267753008288	THF binding site; other site
1267753008289	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1267753008290	substrate binding site [chemical binding]; other site
1267753008291	THF binding site; other site
1267753008292	zinc-binding site [ion binding]; other site
1267753008293	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
1267753008294	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753008295	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
1267753008296	putative dimerization interface [polypeptide binding]; other site
1267753008297	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1267753008298	EamA-like transporter family; Region: EamA; pfam00892
1267753008299	putative hydrolase; Provisional; Region: PRK10976
1267753008300	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753008301	active site
1267753008302	motif I; other site
1267753008303	motif II; other site
1267753008304	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1267753008305	lysophospholipase L2; Provisional; Region: PRK10749
1267753008306	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1267753008307	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
1267753008308	threonine efflux system; Provisional; Region: PRK10229
1267753008309	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
1267753008310	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753008311	ATP binding site [chemical binding]; other site
1267753008312	putative Mg++ binding site [ion binding]; other site
1267753008313	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753008314	nucleotide binding region [chemical binding]; other site
1267753008315	ATP-binding site [chemical binding]; other site
1267753008316	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1267753008317	Helicase and RNase D C-terminal; Region: HRDC; smart00341
1267753008318	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1267753008319	dimerization interface [polypeptide binding]; other site
1267753008320	substrate binding site [chemical binding]; other site
1267753008321	active site
1267753008322	calcium binding site [ion binding]; other site
1267753008323	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1267753008324	CoenzymeA binding site [chemical binding]; other site
1267753008325	subunit interaction site [polypeptide binding]; other site
1267753008326	PHB binding site; other site
1267753008327	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
1267753008328	EamA-like transporter family; Region: EamA; cl17759
1267753008329	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1267753008330	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
1267753008331	Cl binding site [ion binding]; other site
1267753008332	oligomer interface [polypeptide binding]; other site
1267753008333	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
1267753008334	Part of AAA domain; Region: AAA_19; pfam13245
1267753008335	Family description; Region: UvrD_C_2; pfam13538
1267753008336	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
1267753008337	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753008338	motif II; other site
1267753008339	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
1267753008340	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753008341	active site
1267753008342	DNA binding site [nucleotide binding]
1267753008343	Int/Topo IB signature motif; other site
1267753008344	hypothetical protein; Provisional; Region: PRK10963
1267753008345	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1267753008346	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1267753008347	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1267753008348	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
1267753008349	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
1267753008350	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
1267753008351	putative iron binding site [ion binding]; other site
1267753008352	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
1267753008353	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
1267753008354	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
1267753008355	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1267753008356	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1267753008357	domain interfaces; other site
1267753008358	active site
1267753008359	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1267753008360	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1267753008361	active site
1267753008362	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1267753008363	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
1267753008364	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
1267753008365	HemY protein N-terminus; Region: HemY_N; pfam07219
1267753008366	putative transport protein YifK; Provisional; Region: PRK10746
1267753008367	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1267753008368	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1267753008369	putative common antigen polymerase; Provisional; Region: PRK02975
1267753008370	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
1267753008371	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1267753008372	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1267753008373	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1267753008374	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1267753008375	inhibitor-cofactor binding pocket; inhibition site
1267753008376	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753008377	catalytic residue [active]
1267753008378	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
1267753008379	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1267753008380	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1267753008381	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
1267753008382	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1267753008383	NAD binding site [chemical binding]; other site
1267753008384	substrate binding site [chemical binding]; other site
1267753008385	homodimer interface [polypeptide binding]; other site
1267753008386	active site
1267753008387	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
1267753008388	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1267753008389	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1267753008390	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1267753008391	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1267753008392	active site
1267753008393	homodimer interface [polypeptide binding]; other site
1267753008394	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
1267753008395	Chain length determinant protein; Region: Wzz; pfam02706
1267753008396	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
1267753008397	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1267753008398	Mg++ binding site [ion binding]; other site
1267753008399	putative catalytic motif [active]
1267753008400	substrate binding site [chemical binding]; other site
1267753008401	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1267753008402	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1267753008403	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1267753008404	RNA binding site [nucleotide binding]; other site
1267753008405	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1267753008406	multimer interface [polypeptide binding]; other site
1267753008407	Walker A motif; other site
1267753008408	ATP binding site [chemical binding]; other site
1267753008409	Walker B motif; other site
1267753008410	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1267753008411	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1267753008412	catalytic residues [active]
1267753008413	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1267753008414	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1267753008415	ATP binding site [chemical binding]; other site
1267753008416	Mg++ binding site [ion binding]; other site
1267753008417	motif III; other site
1267753008418	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753008419	nucleotide binding region [chemical binding]; other site
1267753008420	ATP-binding site [chemical binding]; other site
1267753008421	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
1267753008422	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1267753008423	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
1267753008424	Part of AAA domain; Region: AAA_19; pfam13245
1267753008425	Family description; Region: UvrD_C_2; pfam13538
1267753008426	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
1267753008427	uridine phosphorylase; Provisional; Region: PRK11178
1267753008428	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1267753008429	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1267753008430	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1267753008431	ligand binding site [chemical binding]; other site
1267753008432	flexible hinge region; other site
1267753008433	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1267753008434	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
1267753008435	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1267753008436	ketol-acid reductoisomerase; Validated; Region: PRK05225
1267753008437	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1267753008438	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1267753008439	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1267753008440	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753008441	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
1267753008442	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
1267753008443	putative dimerization interface [polypeptide binding]; other site
1267753008444	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
1267753008445	threonine dehydratase; Reviewed; Region: PRK09224
1267753008446	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1267753008447	tetramer interface [polypeptide binding]; other site
1267753008448	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753008449	catalytic residue [active]
1267753008450	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
1267753008451	putative Ile/Val binding site [chemical binding]; other site
1267753008452	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
1267753008453	putative Ile/Val binding site [chemical binding]; other site
1267753008454	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
1267753008455	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1267753008456	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1267753008457	homodimer interface [polypeptide binding]; other site
1267753008458	substrate-cofactor binding pocket; other site
1267753008459	catalytic residue [active]
1267753008460	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
1267753008461	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
1267753008462	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1267753008463	PYR/PP interface [polypeptide binding]; other site
1267753008464	dimer interface [polypeptide binding]; other site
1267753008465	TPP binding site [chemical binding]; other site
1267753008466	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1267753008467	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1267753008468	TPP-binding site [chemical binding]; other site
1267753008469	dimer interface [polypeptide binding]; other site
1267753008470	putative ATP-dependent protease; Provisional; Region: PRK09862
1267753008471	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1267753008472	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753008473	Walker A motif; other site
1267753008474	ATP binding site [chemical binding]; other site
1267753008475	Walker B motif; other site
1267753008476	arginine finger; other site
1267753008477	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1267753008478	potential frameshift: common BLAST hit: gi|409247582|ref|YP_006888278.1| UPF0438 protein yifE
1267753008479	transcriptional regulator HdfR; Provisional; Region: PRK03601
1267753008480	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753008481	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1267753008482	dimerization interface [polypeptide binding]; other site
1267753008483	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1267753008484	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753008485	DNA-binding site [nucleotide binding]; DNA binding site
1267753008486	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1267753008487	putative transporter; Provisional; Region: PRK10504
1267753008488	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008489	putative substrate translocation pore; other site
1267753008490	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008491	transcriptional repressor RbsR; Provisional; Region: PRK10423
1267753008492	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753008493	DNA binding site [nucleotide binding]
1267753008494	domain linker motif; other site
1267753008495	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
1267753008496	dimerization interface [polypeptide binding]; other site
1267753008497	ligand binding site [chemical binding]; other site
1267753008498	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753008499	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1267753008500	substrate binding site [chemical binding]; other site
1267753008501	dimer interface [polypeptide binding]; other site
1267753008502	ATP binding site [chemical binding]; other site
1267753008503	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1267753008504	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1267753008505	ligand binding site [chemical binding]; other site
1267753008506	dimerization interface [polypeptide binding]; other site
1267753008507	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1267753008508	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1267753008509	TM-ABC transporter signature motif; other site
1267753008510	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
1267753008511	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1267753008512	Walker A/P-loop; other site
1267753008513	ATP binding site [chemical binding]; other site
1267753008514	Q-loop/lid; other site
1267753008515	ABC transporter signature motif; other site
1267753008516	Walker B; other site
1267753008517	D-loop; other site
1267753008518	H-loop/switch region; other site
1267753008519	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1267753008520	D-ribose pyranase; Provisional; Region: PRK11797
1267753008521	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
1267753008522	potassium uptake protein; Region: kup; TIGR00794
1267753008523	regulatory ATPase RavA; Provisional; Region: PRK13531
1267753008524	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753008525	Walker A motif; other site
1267753008526	ATP binding site [chemical binding]; other site
1267753008527	Walker B motif; other site
1267753008528	arginine finger; other site
1267753008529	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
1267753008530	hypothetical protein; Provisional; Region: yieM; PRK10997
1267753008531	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
1267753008532	metal ion-dependent adhesion site (MIDAS); other site
1267753008533	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1267753008534	dimer interface [polypeptide binding]; other site
1267753008535	active site
1267753008536	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1267753008537	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1267753008538	putative DNA binding site [nucleotide binding]; other site
1267753008539	putative Zn2+ binding site [ion binding]; other site
1267753008540	AsnC family; Region: AsnC_trans_reg; pfam01037
1267753008541	FMN-binding protein MioC; Provisional; Region: PRK09004
1267753008542	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1267753008543	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1267753008544	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1267753008545	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1267753008546	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753008547	S-adenosylmethionine binding site [chemical binding]; other site
1267753008548	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
1267753008549	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1267753008550	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1267753008551	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1267753008552	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1267753008553	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1267753008554	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1267753008555	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1267753008556	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1267753008557	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1267753008558	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1267753008559	beta subunit interaction interface [polypeptide binding]; other site
1267753008560	Walker A motif; other site
1267753008561	ATP binding site [chemical binding]; other site
1267753008562	Walker B motif; other site
1267753008563	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1267753008564	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1267753008565	core domain interface [polypeptide binding]; other site
1267753008566	delta subunit interface [polypeptide binding]; other site
1267753008567	epsilon subunit interface [polypeptide binding]; other site
1267753008568	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1267753008569	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1267753008570	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1267753008571	alpha subunit interaction interface [polypeptide binding]; other site
1267753008572	Walker A motif; other site
1267753008573	ATP binding site [chemical binding]; other site
1267753008574	Walker B motif; other site
1267753008575	inhibitor binding site; inhibition site
1267753008576	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1267753008577	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1267753008578	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1267753008579	gamma subunit interface [polypeptide binding]; other site
1267753008580	epsilon subunit interface [polypeptide binding]; other site
1267753008581	LBP interface [polypeptide binding]; other site
1267753008582	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1267753008583	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
1267753008584	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
1267753008585	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1267753008586	Substrate binding site; other site
1267753008587	Mg++ binding site; other site
1267753008588	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1267753008589	active site
1267753008590	substrate binding site [chemical binding]; other site
1267753008591	CoA binding site [chemical binding]; other site
1267753008592	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1267753008593	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1267753008594	glutaminase active site [active]
1267753008595	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1267753008596	dimer interface [polypeptide binding]; other site
1267753008597	active site
1267753008598	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1267753008599	dimer interface [polypeptide binding]; other site
1267753008600	active site
1267753008601	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1267753008602	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1267753008603	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
1267753008604	potential frameshift: common BLAST hit: gi|409247550|ref|YP_006888247.1| putative shikimate 5-dehydrogenase
1267753008605	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1267753008606	active site
1267753008607	P-loop; other site
1267753008608	phosphorylation site [posttranslational modification]
1267753008609	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
1267753008610	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1267753008611	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753008612	substrate binding pocket [chemical binding]; other site
1267753008613	membrane-bound complex binding site; other site
1267753008614	hinge residues; other site
1267753008615	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
1267753008616	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753008617	dimer interface [polypeptide binding]; other site
1267753008618	conserved gate region; other site
1267753008619	putative PBP binding loops; other site
1267753008620	ABC-ATPase subunit interface; other site
1267753008621	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
1267753008622	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753008623	dimer interface [polypeptide binding]; other site
1267753008624	conserved gate region; other site
1267753008625	putative PBP binding loops; other site
1267753008626	ABC-ATPase subunit interface; other site
1267753008627	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
1267753008628	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1267753008629	Walker A/P-loop; other site
1267753008630	ATP binding site [chemical binding]; other site
1267753008631	Q-loop/lid; other site
1267753008632	ABC transporter signature motif; other site
1267753008633	Walker B; other site
1267753008634	D-loop; other site
1267753008635	H-loop/switch region; other site
1267753008636	transcriptional regulator PhoU; Provisional; Region: PRK11115
1267753008637	PhoU domain; Region: PhoU; pfam01895
1267753008638	PhoU domain; Region: PhoU; pfam01895
1267753008639	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
1267753008640	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753008641	active site
1267753008642	motif I; other site
1267753008643	motif II; other site
1267753008644	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1267753008645	Predicted flavoprotein [General function prediction only]; Region: COG0431
1267753008646	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1267753008647	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1267753008648	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
1267753008649	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753008650	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
1267753008651	substrate binding pocket [chemical binding]; other site
1267753008652	dimerization interface [polypeptide binding]; other site
1267753008653	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
1267753008654	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008655	putative substrate translocation pore; other site
1267753008656	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1267753008657	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1267753008658	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1267753008659	G1 box; other site
1267753008660	GTP/Mg2+ binding site [chemical binding]; other site
1267753008661	Switch I region; other site
1267753008662	G2 box; other site
1267753008663	Switch II region; other site
1267753008664	G3 box; other site
1267753008665	G4 box; other site
1267753008666	G5 box; other site
1267753008667	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1267753008668	membrane protein insertase; Provisional; Region: PRK01318
1267753008669	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1267753008670	hypothetical protein; Validated; Region: PRK00041
1267753008671	ribonuclease P; Reviewed; Region: rnpA; PRK01732
1267753008672	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1267753008673	ent-kaur-16-ene synthase; Region: PLN02279
1267753008674	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1267753008675	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1267753008676	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753008677	Walker A motif; other site
1267753008678	ATP binding site [chemical binding]; other site
1267753008679	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1267753008680	Walker B motif; other site
1267753008681	arginine finger; other site
1267753008682	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1267753008683	DnaA box-binding interface [nucleotide binding]; other site
1267753008684	DNA polymerase III subunit beta; Validated; Region: PRK05643
1267753008685	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1267753008686	putative DNA binding surface [nucleotide binding]; other site
1267753008687	dimer interface [polypeptide binding]; other site
1267753008688	beta-clamp/clamp loader binding surface; other site
1267753008689	beta-clamp/translesion DNA polymerase binding surface; other site
1267753008690	recF protein; Region: recf; TIGR00611
1267753008691	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753008692	Walker A/P-loop; other site
1267753008693	ATP binding site [chemical binding]; other site
1267753008694	Q-loop/lid; other site
1267753008695	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753008696	ABC transporter signature motif; other site
1267753008697	Walker B; other site
1267753008698	D-loop; other site
1267753008699	H-loop/switch region; other site
1267753008700	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1267753008701	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753008702	Mg2+ binding site [ion binding]; other site
1267753008703	G-X-G motif; other site
1267753008704	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1267753008705	anchoring element; other site
1267753008706	dimer interface [polypeptide binding]; other site
1267753008707	ATP binding site [chemical binding]; other site
1267753008708	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1267753008709	active site
1267753008710	putative metal-binding site [ion binding]; other site
1267753008711	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1267753008712	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753008713	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753008714	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1267753008715	putative dimerization interface [polypeptide binding]; other site
1267753008716	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1267753008717	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1267753008718	active site pocket [active]
1267753008719	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008720	D-galactonate transporter; Region: 2A0114; TIGR00893
1267753008721	putative substrate translocation pore; other site
1267753008722	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008723	sugar phosphate phosphatase; Provisional; Region: PRK10513
1267753008724	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753008725	active site
1267753008726	motif I; other site
1267753008727	motif II; other site
1267753008728	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753008729	Surface antigen; Region: Bac_surface_Ag; pfam01103
1267753008730	Protein of unknown function (DUF4056); Region: DUF4056; pfam13265
1267753008731	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
1267753008732	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753008733	dimer interface [polypeptide binding]; other site
1267753008734	phosphorylation site [posttranslational modification]
1267753008735	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753008736	ATP binding site [chemical binding]; other site
1267753008737	Mg2+ binding site [ion binding]; other site
1267753008738	G-X-G motif; other site
1267753008739	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753008740	active site
1267753008741	phosphorylation site [posttranslational modification]
1267753008742	intermolecular recognition site; other site
1267753008743	dimerization interface [polypeptide binding]; other site
1267753008744	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1267753008745	putative binding surface; other site
1267753008746	active site
1267753008747	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
1267753008748	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1267753008749	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
1267753008750	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753008751	active site
1267753008752	phosphorylation site [posttranslational modification]
1267753008753	intermolecular recognition site; other site
1267753008754	dimerization interface [polypeptide binding]; other site
1267753008755	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753008756	DNA binding site [nucleotide binding]
1267753008757	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
1267753008758	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1267753008759	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
1267753008760	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1267753008761	molybdopterin cofactor binding site [chemical binding]; other site
1267753008762	substrate binding site [chemical binding]; other site
1267753008763	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1267753008764	molybdopterin cofactor binding site; other site
1267753008765	chaperone protein TorD; Validated; Region: torD; PRK04976
1267753008766	Haem-binding domain; Region: Haem_bd; pfam14376
1267753008767	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1267753008768	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1267753008769	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753008770	Walker A/P-loop; other site
1267753008771	ATP binding site [chemical binding]; other site
1267753008772	Q-loop/lid; other site
1267753008773	ABC transporter signature motif; other site
1267753008774	Walker B; other site
1267753008775	D-loop; other site
1267753008776	H-loop/switch region; other site
1267753008777	heme exporter protein CcmB; Region: ccmB; TIGR01190
1267753008778	heme exporter protein CcmC; Region: ccmC; TIGR01191
1267753008779	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1267753008780	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1267753008781	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
1267753008782	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
1267753008783	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
1267753008784	catalytic residues [active]
1267753008785	central insert; other site
1267753008786	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
1267753008787	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
1267753008788	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1267753008789	binding surface
1267753008790	TPR motif; other site
1267753008791	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
1267753008792	hypothetical protein; Provisional; Region: PRK11616
1267753008793	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1267753008794	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1267753008795	putative dimer interface [polypeptide binding]; other site
1267753008796	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
1267753008797	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
1267753008798	putative dimer interface [polypeptide binding]; other site
1267753008799	putative transporter; Validated; Region: PRK03818
1267753008800	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
1267753008801	TrkA-C domain; Region: TrkA_C; pfam02080
1267753008802	TrkA-C domain; Region: TrkA_C; pfam02080
1267753008803	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
1267753008804	Predicted membrane protein [Function unknown]; Region: COG2149
1267753008805	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1267753008806	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
1267753008807	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
1267753008808	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
1267753008809	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
1267753008810	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1267753008811	catalytic residue [active]
1267753008812	permease DsdX; Provisional; Region: PRK09921
1267753008813	gluconate transporter; Region: gntP; TIGR00791
1267753008814	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
1267753008815	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753008816	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1267753008817	dimerization interface [polypeptide binding]; other site
1267753008818	substrate binding pocket [chemical binding]; other site
1267753008819	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1267753008820	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
1267753008821	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008822	putative substrate translocation pore; other site
1267753008823	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
1267753008824	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
1267753008825	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
1267753008826	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1267753008827	PYR/PP interface [polypeptide binding]; other site
1267753008828	dimer interface [polypeptide binding]; other site
1267753008829	TPP binding site [chemical binding]; other site
1267753008830	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1267753008831	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1267753008832	TPP-binding site [chemical binding]; other site
1267753008833	dimer interface [polypeptide binding]; other site
1267753008834	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
1267753008835	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1267753008836	putative valine binding site [chemical binding]; other site
1267753008837	dimer interface [polypeptide binding]; other site
1267753008838	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
1267753008839	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1267753008840	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753008841	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753008842	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1267753008843	substrate binding site [chemical binding]; other site
1267753008844	dimer interface [polypeptide binding]; other site
1267753008845	ATP binding site [chemical binding]; other site
1267753008846	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1267753008847	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008848	putative substrate translocation pore; other site
1267753008849	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
1267753008850	active site
1267753008851	catalytic residues [active]
1267753008852	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
1267753008853	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753008854	active site
1267753008855	phosphorylation site [posttranslational modification]
1267753008856	intermolecular recognition site; other site
1267753008857	dimerization interface [polypeptide binding]; other site
1267753008858	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753008859	DNA binding residues [nucleotide binding]
1267753008860	dimerization interface [polypeptide binding]; other site
1267753008861	sensory histidine kinase UhpB; Provisional; Region: PRK11644
1267753008862	MASE1; Region: MASE1; pfam05231
1267753008863	Histidine kinase; Region: HisKA_3; pfam07730
1267753008864	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1267753008865	regulatory protein UhpC; Provisional; Region: PRK11663
1267753008866	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008867	putative substrate translocation pore; other site
1267753008868	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
1267753008869	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008870	putative substrate translocation pore; other site
1267753008871	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
1267753008872	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1267753008873	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753008874	DNA-binding site [nucleotide binding]; DNA binding site
1267753008875	UTRA domain; Region: UTRA; pfam07702
1267753008876	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753008877	active site
1267753008878	phosphorylation site [posttranslational modification]
1267753008879	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1267753008880	active site
1267753008881	P-loop; other site
1267753008882	phosphorylation site [posttranslational modification]
1267753008883	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1267753008884	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1267753008885	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1267753008886	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
1267753008887	putative N- and C-terminal domain interface [polypeptide binding]; other site
1267753008888	putative active site [active]
1267753008889	putative MgATP binding site [chemical binding]; other site
1267753008890	catalytic site [active]
1267753008891	metal binding site [ion binding]; metal-binding site
1267753008892	putative carbohydrate binding site [chemical binding]; other site
1267753008893	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1267753008894	intersubunit interface [polypeptide binding]; other site
1267753008895	active site
1267753008896	zinc binding site [ion binding]; other site
1267753008897	Na+ binding site [ion binding]; other site
1267753008898	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1267753008899	dimerization domain swap beta strand [polypeptide binding]; other site
1267753008900	regulatory protein interface [polypeptide binding]; other site
1267753008901	active site
1267753008902	regulatory phosphorylation site [posttranslational modification]; other site
1267753008903	GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs; Region: GIY-YIG_COG3680; cd10440
1267753008904	GIY-YIG motif/motif A; other site
1267753008905	putative active site [active]
1267753008906	putative metal binding site [ion binding]; other site
1267753008907	Predicted transcriptional regulator [Transcription]; Region: COG2944
1267753008908	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753008909	non-specific DNA binding site [nucleotide binding]; other site
1267753008910	salt bridge; other site
1267753008911	sequence-specific DNA binding site [nucleotide binding]; other site
1267753008912	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
1267753008913	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
1267753008914	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753008915	putative substrate translocation pore; other site
1267753008916	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1267753008917	beta-galactosidase; Region: BGL; TIGR03356
1267753008918	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
1267753008919	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753008920	Walker A motif; other site
1267753008921	ATP binding site [chemical binding]; other site
1267753008922	Walker B motif; other site
1267753008923	arginine finger; other site
1267753008924	Transcriptional antiterminator [Transcription]; Region: COG3933
1267753008925	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
1267753008926	active site
1267753008927	active pocket/dimerization site; other site
1267753008928	phosphorylation site [posttranslational modification]
1267753008929	PRD domain; Region: PRD; pfam00874
1267753008930	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1267753008931	active pocket/dimerization site; other site
1267753008932	active site
1267753008933	phosphorylation site [posttranslational modification]
1267753008934	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1267753008935	active site
1267753008936	phosphorylation site [posttranslational modification]
1267753008937	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
1267753008938	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1267753008939	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
1267753008940	Protein of unknown function (DUF1341); Region: DUF1341; cl06211
1267753008941	hypothetical protein; Provisional; Region: PRK09956
1267753008942	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1267753008943	EamA-like transporter family; Region: EamA; pfam00892
1267753008944	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1267753008945	EamA-like transporter family; Region: EamA; pfam00892
1267753008946	magnesium transport protein MgtC; Provisional; Region: PRK15385
1267753008947	MgtC family; Region: MgtC; pfam02308
1267753008948	magnesium-transporting ATPase; Provisional; Region: PRK15122
1267753008949	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1267753008950	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1267753008951	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1267753008952	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753008953	motif II; other site
1267753008954	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1267753008955	Isochorismatase family; Region: Isochorismatase; pfam00857
1267753008956	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
1267753008957	catalytic triad [active]
1267753008958	dimer interface [polypeptide binding]; other site
1267753008959	conserved cis-peptide bond; other site
1267753008960	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
1267753008961	DNA binding site [nucleotide binding]
1267753008962	autotransport protein MisL; Provisional; Region: PRK15313
1267753008963	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1267753008964	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1267753008965	Transposase; Region: HTH_Tnp_1; cl17663
1267753008966	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
1267753008967	Transposase; Region: HTH_Tnp_1; pfam01527
1267753008968	Virulence protein [General function prediction only]; Region: COG3943
1267753008969	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1267753008970	putative transporter; Provisional; Region: PRK11462
1267753008971	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
1267753008972	putative alpha-glucosidase; Provisional; Region: PRK10658
1267753008973	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1267753008974	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
1267753008975	active site
1267753008976	homotrimer interface [polypeptide binding]; other site
1267753008977	catalytic site [active]
1267753008978	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
1267753008979	AsmA family; Region: AsmA; pfam05170
1267753008980	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
1267753008981	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1267753008982	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
1267753008983	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1267753008984	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1267753008985	generic binding surface II; other site
1267753008986	ssDNA binding site; other site
1267753008987	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1267753008988	ATP binding site [chemical binding]; other site
1267753008989	putative Mg++ binding site [ion binding]; other site
1267753008990	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753008991	nucleotide binding region [chemical binding]; other site
1267753008992	ATP-binding site [chemical binding]; other site
1267753008993	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
1267753008994	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1267753008995	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
1267753008996	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
1267753008997	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1267753008998	Zn2+ binding site [ion binding]; other site
1267753008999	Mg2+ binding site [ion binding]; other site
1267753009000	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1267753009001	synthetase active site [active]
1267753009002	NTP binding site [chemical binding]; other site
1267753009003	metal binding site [ion binding]; metal-binding site
1267753009004	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1267753009005	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1267753009006	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
1267753009007	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1267753009008	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1267753009009	catalytic site [active]
1267753009010	G-X2-G-X-G-K; other site
1267753009011	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
1267753009012	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
1267753009013	nucleotide binding pocket [chemical binding]; other site
1267753009014	K-X-D-G motif; other site
1267753009015	catalytic site [active]
1267753009016	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1267753009017	Predicted membrane protein [Function unknown]; Region: COG2860
1267753009018	UPF0126 domain; Region: UPF0126; pfam03458
1267753009019	UPF0126 domain; Region: UPF0126; pfam03458
1267753009020	potential frameshift: common BLAST hit: gi|194736864|ref|YP_002116679.1| beta-lactamase
1267753009021	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753009022	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753009023	dimerization interface [polypeptide binding]; other site
1267753009024	LysR substrate binding domain; Region: LysR_substrate; pfam03466
1267753009025	hypothetical protein; Provisional; Region: PRK11820
1267753009026	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1267753009027	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1267753009028	ribonuclease PH; Reviewed; Region: rph; PRK00173
1267753009029	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1267753009030	hexamer interface [polypeptide binding]; other site
1267753009031	active site
1267753009032	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1267753009033	active site
1267753009034	division inhibitor protein; Provisional; Region: slmA; PRK09480
1267753009035	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753009036	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1267753009037	trimer interface [polypeptide binding]; other site
1267753009038	active site
1267753009039	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1267753009040	Flavoprotein; Region: Flavoprotein; pfam02441
1267753009041	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1267753009042	hypothetical protein; Reviewed; Region: PRK00024
1267753009043	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1267753009044	MPN+ (JAMM) motif; other site
1267753009045	Zinc-binding site [ion binding]; other site
1267753009046	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1267753009047	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1267753009048	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1267753009049	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1267753009050	DNA binding site [nucleotide binding]
1267753009051	catalytic residue [active]
1267753009052	H2TH interface [polypeptide binding]; other site
1267753009053	putative catalytic residues [active]
1267753009054	turnover-facilitating residue; other site
1267753009055	intercalation triad [nucleotide binding]; other site
1267753009056	8OG recognition residue [nucleotide binding]; other site
1267753009057	putative reading head residues; other site
1267753009058	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1267753009059	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1267753009060	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1267753009061	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1267753009062	active site
1267753009063	(T/H)XGH motif; other site
1267753009064	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1267753009065	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1267753009066	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1267753009067	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
1267753009068	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1267753009069	putative active site [active]
1267753009070	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1267753009071	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1267753009072	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
1267753009073	Glycosyltransferase family 52; Region: Glyco_transf_52; pfam07922
1267753009074	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
1267753009075	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1267753009076	putative ADP-binding pocket [chemical binding]; other site
1267753009077	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1267753009078	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1267753009079	Ligand binding site; other site
1267753009080	metal-binding site
1267753009081	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1267753009082	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
1267753009083	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
1267753009084	Ligand binding site; other site
1267753009085	metal-binding site
1267753009086	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
1267753009087	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
1267753009088	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
1267753009089	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
1267753009090	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1267753009091	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
1267753009092	O-antigen ligase RfaL; Provisional; Region: PRK15487
1267753009093	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1267753009094	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1267753009095	putative active site [active]
1267753009096	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1267753009097	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1267753009098	putative active site [active]
1267753009099	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
1267753009100	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
1267753009101	NADP binding site [chemical binding]; other site
1267753009102	homopentamer interface [polypeptide binding]; other site
1267753009103	substrate binding site [chemical binding]; other site
1267753009104	active site
1267753009105	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1267753009106	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1267753009107	substrate-cofactor binding pocket; other site
1267753009108	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753009109	catalytic residue [active]
1267753009110	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1267753009111	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1267753009112	NAD(P) binding site [chemical binding]; other site
1267753009113	putative glycosyl transferase; Provisional; Region: PRK10073
1267753009114	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1267753009115	active site
1267753009116	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1267753009117	NodB motif; other site
1267753009118	putative active site [active]
1267753009119	putative catalytic site [active]
1267753009120	Zn binding site [ion binding]; other site
1267753009121	AmiB activator; Provisional; Region: PRK11637
1267753009122	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
1267753009123	Peptidase family M23; Region: Peptidase_M23; pfam01551
1267753009124	phosphoglyceromutase; Provisional; Region: PRK05434
1267753009125	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
1267753009126	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1267753009127	active site residue [active]
1267753009128	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1267753009129	GSH binding site [chemical binding]; other site
1267753009130	catalytic residues [active]
1267753009131	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
1267753009132	SecA binding site; other site
1267753009133	Preprotein binding site; other site
1267753009134	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1267753009135	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1267753009136	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1267753009137	serine acetyltransferase; Provisional; Region: cysE; PRK11132
1267753009138	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
1267753009139	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1267753009140	trimer interface [polypeptide binding]; other site
1267753009141	active site
1267753009142	substrate binding site [chemical binding]; other site
1267753009143	CoA binding site [chemical binding]; other site
1267753009144	putative rRNA methylase; Provisional; Region: PRK10358
1267753009145	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
1267753009146	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
1267753009147	active site
1267753009148	substrate binding site [chemical binding]; other site
1267753009149	FMN binding site [chemical binding]; other site
1267753009150	putative catalytic residues [active]
1267753009151	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
1267753009152	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753009153	DNA-binding site [nucleotide binding]; DNA binding site
1267753009154	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1267753009155	L-lactate permease; Provisional; Region: PRK10420
1267753009156	glycolate transporter; Provisional; Region: PRK09695
1267753009157	potential frameshift: common BLAST hit: gi|194734122|ref|YP_002116628.1| autotransporter
1267753009158	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
1267753009159	hypothetical protein; Provisional; Region: PRK11020
1267753009160	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1267753009161	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
1267753009162	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1267753009163	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1267753009164	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1267753009165	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1267753009166	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1267753009167	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1267753009168	active site
1267753009169	P-loop; other site
1267753009170	phosphorylation site [posttranslational modification]
1267753009171	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753009172	active site
1267753009173	phosphorylation site [posttranslational modification]
1267753009174	putative glutathione S-transferase; Provisional; Region: PRK10357
1267753009175	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
1267753009176	putative C-terminal domain interface [polypeptide binding]; other site
1267753009177	putative GSH binding site (G-site) [chemical binding]; other site
1267753009178	putative dimer interface [polypeptide binding]; other site
1267753009179	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
1267753009180	dimer interface [polypeptide binding]; other site
1267753009181	N-terminal domain interface [polypeptide binding]; other site
1267753009182	putative substrate binding pocket (H-site) [chemical binding]; other site
1267753009183	selenocysteine synthase; Provisional; Region: PRK04311
1267753009184	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1267753009185	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1267753009186	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1267753009187	catalytic residue [active]
1267753009188	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
1267753009189	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1267753009190	G1 box; other site
1267753009191	putative GEF interaction site [polypeptide binding]; other site
1267753009192	GTP/Mg2+ binding site [chemical binding]; other site
1267753009193	Switch I region; other site
1267753009194	G2 box; other site
1267753009195	G3 box; other site
1267753009196	Switch II region; other site
1267753009197	G4 box; other site
1267753009198	G5 box; other site
1267753009199	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1267753009200	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1267753009201	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1267753009202	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1267753009203	putative alcohol dehydrogenase; Provisional; Region: PRK09860
1267753009204	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1267753009205	dimer interface [polypeptide binding]; other site
1267753009206	active site
1267753009207	metal binding site [ion binding]; metal-binding site
1267753009208	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1267753009209	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1267753009210	nucleotide binding site [chemical binding]; other site
1267753009211	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1267753009212	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1267753009213	NAD(P) binding site [chemical binding]; other site
1267753009214	catalytic residues [active]
1267753009215	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1267753009216	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
1267753009217	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1267753009218	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1267753009219	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753009220	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1267753009221	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1267753009222	intersubunit interface [polypeptide binding]; other site
1267753009223	active site
1267753009224	Zn2+ binding site [ion binding]; other site
1267753009225	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1267753009226	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1267753009227	AP (apurinic/apyrimidinic) site pocket; other site
1267753009228	DNA interaction; other site
1267753009229	Metal-binding active site; metal-binding site
1267753009230	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1267753009231	active site
1267753009232	dimer interface [polypeptide binding]; other site
1267753009233	magnesium binding site [ion binding]; other site
1267753009234	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
1267753009235	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
1267753009236	putative N- and C-terminal domain interface [polypeptide binding]; other site
1267753009237	putative active site [active]
1267753009238	MgATP binding site [chemical binding]; other site
1267753009239	catalytic site [active]
1267753009240	metal binding site [ion binding]; metal-binding site
1267753009241	putative xylulose binding site [chemical binding]; other site
1267753009242	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
1267753009243	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
1267753009244	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
1267753009245	DctM-like transporters; Region: DctM; pfam06808
1267753009246	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
1267753009247	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1267753009248	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
1267753009249	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1267753009250	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
1267753009251	Bacterial transcriptional regulator; Region: IclR; pfam01614
1267753009252	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1267753009253	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
1267753009254	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753009255	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753009256	homodimer interface [polypeptide binding]; other site
1267753009257	catalytic residue [active]
1267753009258	alpha-amylase; Reviewed; Region: malS; PRK09505
1267753009259	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1267753009260	active site
1267753009261	catalytic site [active]
1267753009262	hypothetical protein; Provisional; Region: PRK10356
1267753009263	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1267753009264	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
1267753009265	putative dimerization interface [polypeptide binding]; other site
1267753009266	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1267753009267	putative ligand binding site [chemical binding]; other site
1267753009268	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753009269	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1267753009270	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753009271	xylose isomerase; Provisional; Region: PRK05474
1267753009272	xylose isomerase; Region: xylose_isom_A; TIGR02630
1267753009273	xylulokinase; Provisional; Region: PRK15027
1267753009274	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
1267753009275	N- and C-terminal domain interface [polypeptide binding]; other site
1267753009276	active site
1267753009277	MgATP binding site [chemical binding]; other site
1267753009278	catalytic site [active]
1267753009279	metal binding site [ion binding]; metal-binding site
1267753009280	xylulose binding site [chemical binding]; other site
1267753009281	homodimer interface [polypeptide binding]; other site
1267753009282	Predicted membrane protein [Function unknown]; Region: COG4682
1267753009283	yiaA/B two helix domain; Region: YiaAB; pfam05360
1267753009284	yiaA/B two helix domain; Region: YiaAB; cl01759
1267753009285	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1267753009286	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1267753009287	YsaB-like lipoprotein; Region: YsaB; pfam13983
1267753009288	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1267753009289	dimer interface [polypeptide binding]; other site
1267753009290	motif 1; other site
1267753009291	active site
1267753009292	motif 2; other site
1267753009293	motif 3; other site
1267753009294	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1267753009295	DALR anticodon binding domain; Region: DALR_1; pfam05746
1267753009296	HNH endonuclease; Region: HNH_2; pfam13391
1267753009297	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
1267753009298	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1267753009299	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1267753009300	DNA-binding site [nucleotide binding]; DNA binding site
1267753009301	RNA-binding motif; other site
1267753009302	Predicted transcriptional regulator [Transcription]; Region: COG2944
1267753009303	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753009304	salt bridge; other site
1267753009305	non-specific DNA binding site [nucleotide binding]; other site
1267753009306	sequence-specific DNA binding site [nucleotide binding]; other site
1267753009307	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
1267753009308	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
1267753009309	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
1267753009310	dimerization interface [polypeptide binding]; other site
1267753009311	ligand binding site [chemical binding]; other site
1267753009312	NADP binding site [chemical binding]; other site
1267753009313	catalytic site [active]
1267753009314	putative outer membrane lipoprotein; Provisional; Region: PRK10510
1267753009315	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1267753009316	ligand binding site [chemical binding]; other site
1267753009317	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1267753009318	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1267753009319	molybdopterin cofactor binding site [chemical binding]; other site
1267753009320	substrate binding site [chemical binding]; other site
1267753009321	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1267753009322	molybdopterin cofactor binding site; other site
1267753009323	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753009324	Coenzyme A binding pocket [chemical binding]; other site
1267753009325	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
1267753009326	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
1267753009327	phosphoethanolamine transferase; Provisional; Region: PRK11560
1267753009328	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1267753009329	Sulfatase; Region: Sulfatase; pfam00884
1267753009330	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1267753009331	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753009332	DNA binding site [nucleotide binding]
1267753009333	domain linker motif; other site
1267753009334	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
1267753009335	putative dimerization interface [polypeptide binding]; other site
1267753009336	putative ligand binding site [chemical binding]; other site
1267753009337	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
1267753009338	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1267753009339	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1267753009340	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
1267753009341	peptide binding site [polypeptide binding]; other site
1267753009342	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1267753009343	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753009344	dimer interface [polypeptide binding]; other site
1267753009345	conserved gate region; other site
1267753009346	putative PBP binding loops; other site
1267753009347	ABC-ATPase subunit interface; other site
1267753009348	dipeptide transporter; Provisional; Region: PRK10913
1267753009349	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1267753009350	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753009351	dimer interface [polypeptide binding]; other site
1267753009352	conserved gate region; other site
1267753009353	putative PBP binding loops; other site
1267753009354	ABC-ATPase subunit interface; other site
1267753009355	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
1267753009356	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753009357	Walker A/P-loop; other site
1267753009358	ATP binding site [chemical binding]; other site
1267753009359	Q-loop/lid; other site
1267753009360	ABC transporter signature motif; other site
1267753009361	Walker B; other site
1267753009362	D-loop; other site
1267753009363	H-loop/switch region; other site
1267753009364	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1267753009365	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1267753009366	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1267753009367	Walker A/P-loop; other site
1267753009368	ATP binding site [chemical binding]; other site
1267753009369	Q-loop/lid; other site
1267753009370	ABC transporter signature motif; other site
1267753009371	Walker B; other site
1267753009372	D-loop; other site
1267753009373	H-loop/switch region; other site
1267753009374	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1267753009375	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1267753009376	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1267753009377	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1267753009378	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1267753009379	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
1267753009380	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
1267753009381	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
1267753009382	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
1267753009383	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
1267753009384	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
1267753009385	cell division protein; Provisional; Region: PRK10037
1267753009386	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
1267753009387	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1267753009388	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
1267753009389	DXD motif; other site
1267753009390	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1267753009391	PilZ domain; Region: PilZ; pfam07238
1267753009392	cellulose synthase regulator protein; Provisional; Region: PRK11114
1267753009393	endo-1,4-D-glucanase; Provisional; Region: PRK11097
1267753009394	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
1267753009395	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1267753009396	TPR motif; other site
1267753009397	binding surface
1267753009398	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1267753009399	binding surface
1267753009400	TPR motif; other site
1267753009401	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
1267753009402	putative diguanylate cyclase; Provisional; Region: PRK13561
1267753009403	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753009404	metal binding site [ion binding]; metal-binding site
1267753009405	active site
1267753009406	I-site; other site
1267753009407	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753009408	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
1267753009409	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1267753009410	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1267753009411	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1267753009412	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753009413	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1267753009414	substrate binding site [chemical binding]; other site
1267753009415	ATP binding site [chemical binding]; other site
1267753009416	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753009417	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
1267753009418	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1267753009419	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753009420	metabolite-proton symporter; Region: 2A0106; TIGR00883
1267753009421	putative substrate translocation pore; other site
1267753009422	potential frameshift: common BLAST hit: gi|194736490|ref|YP_002116545.1| ribonuclease
1267753009423	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753009424	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753009425	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
1267753009426	putative effector binding pocket; other site
1267753009427	putative dimerization interface [polypeptide binding]; other site
1267753009428	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1267753009429	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1267753009430	active site
1267753009431	phosphorylation site [posttranslational modification]
1267753009432	dimerization interface [polypeptide binding]; other site
1267753009433	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753009434	DNA binding residues [nucleotide binding]
1267753009435	dimerization interface [polypeptide binding]; other site
1267753009436	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
1267753009437	catalytic residue [active]
1267753009438	trehalase; Provisional; Region: treF; PRK13270
1267753009439	Trehalase; Region: Trehalase; pfam01204
1267753009440	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1267753009441	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753009442	DNA-binding site [nucleotide binding]; DNA binding site
1267753009443	UTRA domain; Region: UTRA; pfam07702
1267753009444	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
1267753009445	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
1267753009446	putative active site [active]
1267753009447	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1267753009448	dimer interface [polypeptide binding]; other site
1267753009449	active site
1267753009450	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
1267753009451	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753009452	substrate binding site [chemical binding]; other site
1267753009453	ATP binding site [chemical binding]; other site
1267753009454	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1267753009455	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1267753009456	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1267753009457	active site
1267753009458	homodimer interface [polypeptide binding]; other site
1267753009459	homotetramer interface [polypeptide binding]; other site
1267753009460	glutathione reductase; Validated; Region: PRK06116
1267753009461	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1267753009462	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753009463	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1267753009464	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
1267753009465	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
1267753009466	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1267753009467	active site
1267753009468	oligopeptidase A; Provisional; Region: PRK10911
1267753009469	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1267753009470	active site
1267753009471	Zn binding site [ion binding]; other site
1267753009472	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753009473	S-adenosylmethionine binding site [chemical binding]; other site
1267753009474	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
1267753009475	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753009476	putative substrate translocation pore; other site
1267753009477	POT family; Region: PTR2; pfam00854
1267753009478	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1267753009479	Ligand Binding Site [chemical binding]; other site
1267753009480	universal stress protein UspB; Provisional; Region: PRK04960
1267753009481	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1267753009482	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1267753009483	Predicted flavoproteins [General function prediction only]; Region: COG2081
1267753009484	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1267753009485	HlyD family secretion protein; Region: HlyD; pfam00529
1267753009486	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753009487	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753009488	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1267753009489	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
1267753009490	Walker A/P-loop; other site
1267753009491	ATP binding site [chemical binding]; other site
1267753009492	Q-loop/lid; other site
1267753009493	ABC transporter signature motif; other site
1267753009494	Walker B; other site
1267753009495	D-loop; other site
1267753009496	H-loop/switch region; other site
1267753009497	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1267753009498	Walker A/P-loop; other site
1267753009499	ATP binding site [chemical binding]; other site
1267753009500	Q-loop/lid; other site
1267753009501	ABC transporter signature motif; other site
1267753009502	Walker B; other site
1267753009503	D-loop; other site
1267753009504	H-loop/switch region; other site
1267753009505	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1267753009506	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1267753009507	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1267753009508	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1267753009509	nickel responsive regulator; Provisional; Region: PRK02967
1267753009510	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
1267753009511	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
1267753009512	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
1267753009513	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1267753009514	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1267753009515	major facilitator superfamily transporter; Provisional; Region: PRK05122
1267753009516	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753009517	putative substrate translocation pore; other site
1267753009518	hypothetical protein; Provisional; Region: PRK11615
1267753009519	hypothetical protein; Provisional; Region: PRK11212
1267753009520	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
1267753009521	CPxP  motif; other site
1267753009522	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
1267753009523	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
1267753009524	dimer interface [polypeptide binding]; other site
1267753009525	ligand binding site [chemical binding]; other site
1267753009526	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753009527	dimerization interface [polypeptide binding]; other site
1267753009528	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1267753009529	dimer interface [polypeptide binding]; other site
1267753009530	putative CheW interface [polypeptide binding]; other site
1267753009531	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
1267753009532	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1267753009533	metal-binding site [ion binding]
1267753009534	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1267753009535	Predicted membrane protein [Function unknown]; Region: COG3714
1267753009536	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
1267753009537	hypothetical protein; Provisional; Region: PRK10910
1267753009538	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1267753009539	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753009540	S-adenosylmethionine binding site [chemical binding]; other site
1267753009541	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1267753009542	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1267753009543	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1267753009544	P loop; other site
1267753009545	GTP binding site [chemical binding]; other site
1267753009546	cell division protein FtsE; Provisional; Region: PRK10908
1267753009547	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753009548	Walker A/P-loop; other site
1267753009549	ATP binding site [chemical binding]; other site
1267753009550	Q-loop/lid; other site
1267753009551	ABC transporter signature motif; other site
1267753009552	Walker B; other site
1267753009553	D-loop; other site
1267753009554	H-loop/switch region; other site
1267753009555	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
1267753009556	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1267753009557	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
1267753009558	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1267753009559	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1267753009560	DNA binding residues [nucleotide binding]
1267753009561	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1267753009562	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1267753009563	dimerization interface [polypeptide binding]; other site
1267753009564	ligand binding site [chemical binding]; other site
1267753009565	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
1267753009566	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1267753009567	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
1267753009568	dimerization interface [polypeptide binding]; other site
1267753009569	ligand binding site [chemical binding]; other site
1267753009570	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1267753009571	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1267753009572	TM-ABC transporter signature motif; other site
1267753009573	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
1267753009574	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
1267753009575	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1267753009576	TM-ABC transporter signature motif; other site
1267753009577	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
1267753009578	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1267753009579	Walker A/P-loop; other site
1267753009580	ATP binding site [chemical binding]; other site
1267753009581	Q-loop/lid; other site
1267753009582	ABC transporter signature motif; other site
1267753009583	Walker B; other site
1267753009584	D-loop; other site
1267753009585	H-loop/switch region; other site
1267753009586	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
1267753009587	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1267753009588	Walker A/P-loop; other site
1267753009589	ATP binding site [chemical binding]; other site
1267753009590	Q-loop/lid; other site
1267753009591	ABC transporter signature motif; other site
1267753009592	Walker B; other site
1267753009593	D-loop; other site
1267753009594	H-loop/switch region; other site
1267753009595	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
1267753009596	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1267753009597	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1267753009598	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753009599	dimer interface [polypeptide binding]; other site
1267753009600	conserved gate region; other site
1267753009601	putative PBP binding loops; other site
1267753009602	ABC-ATPase subunit interface; other site
1267753009603	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1267753009604	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753009605	dimer interface [polypeptide binding]; other site
1267753009606	conserved gate region; other site
1267753009607	ABC-ATPase subunit interface; other site
1267753009608	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1267753009609	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1267753009610	Walker A/P-loop; other site
1267753009611	ATP binding site [chemical binding]; other site
1267753009612	Q-loop/lid; other site
1267753009613	ABC transporter signature motif; other site
1267753009614	Walker B; other site
1267753009615	D-loop; other site
1267753009616	H-loop/switch region; other site
1267753009617	TOBE domain; Region: TOBE_2; pfam08402
1267753009618	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
1267753009619	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
1267753009620	putative active site [active]
1267753009621	catalytic site [active]
1267753009622	putative metal binding site [ion binding]; other site
1267753009623	hypothetical protein; Provisional; Region: PRK10350
1267753009624	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
1267753009625	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
1267753009626	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
1267753009627	active site
1267753009628	substrate binding pocket [chemical binding]; other site
1267753009629	homodimer interaction site [polypeptide binding]; other site
1267753009630	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
1267753009631	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1267753009632	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1267753009633	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753009634	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1267753009635	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753009636	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1267753009637	substrate binding site [chemical binding]; other site
1267753009638	dimer interface [polypeptide binding]; other site
1267753009639	ATP binding site [chemical binding]; other site
1267753009640	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1267753009641	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753009642	Coenzyme A binding pocket [chemical binding]; other site
1267753009643	putative oxidoreductase; Provisional; Region: PRK10206
1267753009644	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1267753009645	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1267753009646	Pirin-related protein [General function prediction only]; Region: COG1741
1267753009647	Pirin; Region: Pirin; pfam02678
1267753009648	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
1267753009649	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753009650	DNA binding site [nucleotide binding]
1267753009651	domain linker motif; other site
1267753009652	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1267753009653	putative ligand binding site [chemical binding]; other site
1267753009654	putative dimerization interface [polypeptide binding]; other site
1267753009655	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
1267753009656	ATP-binding site [chemical binding]; other site
1267753009657	Gluconate-6-phosphate binding site [chemical binding]; other site
1267753009658	low affinity gluconate transporter; Provisional; Region: PRK10472
1267753009659	gluconate transporter; Region: gntP; TIGR00791
1267753009660	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
1267753009661	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1267753009662	glycogen branching enzyme; Provisional; Region: PRK05402
1267753009663	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1267753009664	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1267753009665	active site
1267753009666	catalytic site [active]
1267753009667	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1267753009668	glycogen debranching enzyme; Provisional; Region: PRK03705
1267753009669	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
1267753009670	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
1267753009671	active site
1267753009672	catalytic site [active]
1267753009673	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
1267753009674	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1267753009675	ligand binding site; other site
1267753009676	oligomer interface; other site
1267753009677	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1267753009678	dimer interface [polypeptide binding]; other site
1267753009679	N-terminal domain interface [polypeptide binding]; other site
1267753009680	sulfate 1 binding site; other site
1267753009681	glycogen synthase; Provisional; Region: glgA; PRK00654
1267753009682	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1267753009683	ADP-binding pocket [chemical binding]; other site
1267753009684	homodimer interface [polypeptide binding]; other site
1267753009685	glycogen phosphorylase; Provisional; Region: PRK14986
1267753009686	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1267753009687	homodimer interface [polypeptide binding]; other site
1267753009688	active site pocket [active]
1267753009689	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
1267753009690	hypothetical protein; Provisional; Region: PRK09781; cl08057
1267753009691	hypothetical protein; Provisional; Region: PRK09781; cl08057
1267753009692	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
1267753009693	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
1267753009694	active site residue [active]
1267753009695	intramembrane serine protease GlpG; Provisional; Region: PRK10907
1267753009696	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
1267753009697	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1267753009698	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
1267753009699	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1267753009700	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753009701	transcriptional regulator MalT; Provisional; Region: PRK04841
1267753009702	AAA ATPase domain; Region: AAA_16; pfam13191
1267753009703	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753009704	DNA binding residues [nucleotide binding]
1267753009705	dimerization interface [polypeptide binding]; other site
1267753009706	maltodextrin phosphorylase; Provisional; Region: PRK14985
1267753009707	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1267753009708	homodimer interface [polypeptide binding]; other site
1267753009709	active site pocket [active]
1267753009710	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
1267753009711	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
1267753009712	high-affinity gluconate transporter; Provisional; Region: PRK14984
1267753009713	gluconate transporter; Region: gntP; TIGR00791
1267753009714	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
1267753009715	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1267753009716	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1267753009717	DNA utilization protein GntX; Provisional; Region: PRK11595
1267753009718	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1267753009719	active site
1267753009720	carboxylesterase BioH; Provisional; Region: PRK10349
1267753009721	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
1267753009722	hypothetical protein; Provisional; Region: PRK09956
1267753009723	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
1267753009724	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
1267753009725	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
1267753009726	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1267753009727	G1 box; other site
1267753009728	GTP/Mg2+ binding site [chemical binding]; other site
1267753009729	Switch I region; other site
1267753009730	G2 box; other site
1267753009731	G3 box; other site
1267753009732	Switch II region; other site
1267753009733	G4 box; other site
1267753009734	G5 box; other site
1267753009735	Nucleoside recognition; Region: Gate; pfam07670
1267753009736	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1267753009737	Nucleoside recognition; Region: Gate; pfam07670
1267753009738	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
1267753009739	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1267753009740	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1267753009741	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1267753009742	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1267753009743	RNA binding site [nucleotide binding]; other site
1267753009744	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
1267753009745	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1267753009746	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1267753009747	osmolarity response regulator; Provisional; Region: ompR; PRK09468
1267753009748	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753009749	active site
1267753009750	phosphorylation site [posttranslational modification]
1267753009751	intermolecular recognition site; other site
1267753009752	dimerization interface [polypeptide binding]; other site
1267753009753	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753009754	DNA binding site [nucleotide binding]
1267753009755	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
1267753009756	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753009757	dimerization interface [polypeptide binding]; other site
1267753009758	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753009759	dimer interface [polypeptide binding]; other site
1267753009760	phosphorylation site [posttranslational modification]
1267753009761	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753009762	ATP binding site [chemical binding]; other site
1267753009763	G-X-G motif; other site
1267753009764	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1267753009765	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1267753009766	active site
1267753009767	substrate-binding site [chemical binding]; other site
1267753009768	metal-binding site [ion binding]
1267753009769	ATP binding site [chemical binding]; other site
1267753009770	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
1267753009771	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1267753009772	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1267753009773	dimerization interface [polypeptide binding]; other site
1267753009774	domain crossover interface; other site
1267753009775	redox-dependent activation switch; other site
1267753009776	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1267753009777	RNA binding surface [nucleotide binding]; other site
1267753009778	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1267753009779	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753009780	motif II; other site
1267753009781	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
1267753009782	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
1267753009783	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1267753009784	ADP-ribose binding site [chemical binding]; other site
1267753009785	dimer interface [polypeptide binding]; other site
1267753009786	active site
1267753009787	nudix motif; other site
1267753009788	metal binding site [ion binding]; metal-binding site
1267753009789	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
1267753009790	Transglycosylase; Region: Transgly; pfam00912
1267753009791	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1267753009792	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
1267753009793	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1267753009794	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
1267753009795	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
1267753009796	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1267753009797	shikimate kinase; Reviewed; Region: aroK; PRK00131
1267753009798	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1267753009799	ADP binding site [chemical binding]; other site
1267753009800	magnesium binding site [ion binding]; other site
1267753009801	putative shikimate binding site; other site
1267753009802	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1267753009803	active site
1267753009804	dimer interface [polypeptide binding]; other site
1267753009805	metal binding site [ion binding]; metal-binding site
1267753009806	cell division protein DamX; Validated; Region: PRK10905
1267753009807	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
1267753009808	DNA adenine methylase; Provisional; Region: PRK10904
1267753009809	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1267753009810	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1267753009811	substrate binding site [chemical binding]; other site
1267753009812	hexamer interface [polypeptide binding]; other site
1267753009813	metal binding site [ion binding]; metal-binding site
1267753009814	phosphoglycolate phosphatase; Provisional; Region: PRK13222
1267753009815	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753009816	motif II; other site
1267753009817	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1267753009818	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1267753009819	active site
1267753009820	HIGH motif; other site
1267753009821	dimer interface [polypeptide binding]; other site
1267753009822	KMSKS motif; other site
1267753009823	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
1267753009824	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1267753009825	siroheme synthase; Provisional; Region: cysG; PRK10637
1267753009826	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1267753009827	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
1267753009828	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1267753009829	active site
1267753009830	SAM binding site [chemical binding]; other site
1267753009831	homodimer interface [polypeptide binding]; other site
1267753009832	nitrite transporter NirC; Provisional; Region: PRK11562
1267753009833	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
1267753009834	nitrite reductase subunit NirD; Provisional; Region: PRK14989
1267753009835	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753009836	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1267753009837	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1267753009838	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1267753009839	putative transporter; Provisional; Region: PRK03699
1267753009840	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753009841	putative substrate translocation pore; other site
1267753009842	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
1267753009843	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
1267753009844	substrate binding site [chemical binding]; other site
1267753009845	hypothetical protein; Provisional; Region: PRK10204
1267753009846	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
1267753009847	cell filamentation protein Fic; Provisional; Region: PRK10347
1267753009848	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1267753009849	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1267753009850	glutamine binding [chemical binding]; other site
1267753009851	catalytic triad [active]
1267753009852	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
1267753009853	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1267753009854	inhibitor-cofactor binding pocket; inhibition site
1267753009855	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753009856	catalytic residue [active]
1267753009857	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
1267753009858	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
1267753009859	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1267753009860	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
1267753009861	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1267753009862	ligand binding site [chemical binding]; other site
1267753009863	flexible hinge region; other site
1267753009864	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1267753009865	putative switch regulator; other site
1267753009866	non-specific DNA interactions [nucleotide binding]; other site
1267753009867	DNA binding site [nucleotide binding]
1267753009868	sequence specific DNA binding site [nucleotide binding]; other site
1267753009869	putative cAMP binding site [chemical binding]; other site
1267753009870	hypothetical protein; Provisional; Region: PRK10738
1267753009871	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
1267753009872	active site
1267753009873	hypothetical protein; Provisional; Region: PRK04966
1267753009874	putative hydrolase; Provisional; Region: PRK10985
1267753009875	putative monooxygenase; Provisional; Region: PRK11118
1267753009876	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753009877	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753009878	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
1267753009879	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753009880	Walker A/P-loop; other site
1267753009881	ATP binding site [chemical binding]; other site
1267753009882	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753009883	ABC transporter signature motif; other site
1267753009884	Walker B; other site
1267753009885	D-loop; other site
1267753009886	ABC transporter; Region: ABC_tran_2; pfam12848
1267753009887	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1267753009888	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
1267753009889	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
1267753009890	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1267753009891	TrkA-N domain; Region: TrkA_N; pfam02254
1267753009892	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
1267753009893	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1267753009894	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1267753009895	phi X174 lysis protein; Provisional; Region: PRK02793
1267753009896	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
1267753009897	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
1267753009898	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1267753009899	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1267753009900	YheO-like PAS domain; Region: PAS_6; pfam08348
1267753009901	HTH domain; Region: HTH_22; pfam13309
1267753009902	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
1267753009903	sulfur relay protein TusC; Validated; Region: PRK00211
1267753009904	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
1267753009905	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1267753009906	S17 interaction site [polypeptide binding]; other site
1267753009907	S8 interaction site; other site
1267753009908	16S rRNA interaction site [nucleotide binding]; other site
1267753009909	streptomycin interaction site [chemical binding]; other site
1267753009910	23S rRNA interaction site [nucleotide binding]; other site
1267753009911	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1267753009912	30S ribosomal protein S7; Validated; Region: PRK05302
1267753009913	elongation factor G; Reviewed; Region: PRK00007
1267753009914	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1267753009915	G1 box; other site
1267753009916	putative GEF interaction site [polypeptide binding]; other site
1267753009917	GTP/Mg2+ binding site [chemical binding]; other site
1267753009918	Switch I region; other site
1267753009919	G2 box; other site
1267753009920	G3 box; other site
1267753009921	Switch II region; other site
1267753009922	G4 box; other site
1267753009923	G5 box; other site
1267753009924	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1267753009925	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1267753009926	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1267753009927	elongation factor Tu; Reviewed; Region: PRK00049
1267753009928	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1267753009929	G1 box; other site
1267753009930	GEF interaction site [polypeptide binding]; other site
1267753009931	GTP/Mg2+ binding site [chemical binding]; other site
1267753009932	Switch I region; other site
1267753009933	G2 box; other site
1267753009934	G3 box; other site
1267753009935	Switch II region; other site
1267753009936	G4 box; other site
1267753009937	G5 box; other site
1267753009938	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1267753009939	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1267753009940	Antibiotic Binding Site [chemical binding]; other site
1267753009941	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
1267753009942	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
1267753009943	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
1267753009944	heme binding site [chemical binding]; other site
1267753009945	ferroxidase pore; other site
1267753009946	ferroxidase diiron center [ion binding]; other site
1267753009947	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1267753009948	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1267753009949	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1267753009950	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
1267753009951	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1267753009952	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1267753009953	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1267753009954	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1267753009955	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1267753009956	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1267753009957	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1267753009958	protein-rRNA interface [nucleotide binding]; other site
1267753009959	putative translocon binding site; other site
1267753009960	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1267753009961	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1267753009962	G-X-X-G motif; other site
1267753009963	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1267753009964	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1267753009965	23S rRNA interface [nucleotide binding]; other site
1267753009966	5S rRNA interface [nucleotide binding]; other site
1267753009967	putative antibiotic binding site [chemical binding]; other site
1267753009968	L25 interface [polypeptide binding]; other site
1267753009969	L27 interface [polypeptide binding]; other site
1267753009970	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1267753009971	23S rRNA interface [nucleotide binding]; other site
1267753009972	putative translocon interaction site; other site
1267753009973	signal recognition particle (SRP54) interaction site; other site
1267753009974	L23 interface [polypeptide binding]; other site
1267753009975	trigger factor interaction site; other site
1267753009976	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1267753009977	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1267753009978	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1267753009979	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1267753009980	RNA binding site [nucleotide binding]; other site
1267753009981	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1267753009982	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1267753009983	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1267753009984	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1267753009985	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1267753009986	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1267753009987	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1267753009988	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1267753009989	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1267753009990	23S rRNA interface [nucleotide binding]; other site
1267753009991	5S rRNA interface [nucleotide binding]; other site
1267753009992	L27 interface [polypeptide binding]; other site
1267753009993	L5 interface [polypeptide binding]; other site
1267753009994	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1267753009995	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1267753009996	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1267753009997	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1267753009998	23S rRNA binding site [nucleotide binding]; other site
1267753009999	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1267753010000	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1267753010001	SecY translocase; Region: SecY; pfam00344
1267753010002	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1267753010003	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1267753010004	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1267753010005	30S ribosomal protein S11; Validated; Region: PRK05309
1267753010006	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1267753010007	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1267753010008	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1267753010009	RNA binding surface [nucleotide binding]; other site
1267753010010	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1267753010011	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1267753010012	alphaNTD homodimer interface [polypeptide binding]; other site
1267753010013	alphaNTD - beta interaction site [polypeptide binding]; other site
1267753010014	alphaNTD - beta' interaction site [polypeptide binding]; other site
1267753010015	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1267753010016	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1267753010017	hypothetical protein; Provisional; Region: PRK10203
1267753010018	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
1267753010019	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
1267753010020	DNA binding residues [nucleotide binding]
1267753010021	dimer interface [polypeptide binding]; other site
1267753010022	metal binding site [ion binding]; metal-binding site
1267753010023	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
1267753010024	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1267753010025	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1267753010026	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
1267753010027	TrkA-N domain; Region: TrkA_N; pfam02254
1267753010028	TrkA-C domain; Region: TrkA_C; pfam02080
1267753010029	TrkA-N domain; Region: TrkA_N; pfam02254
1267753010030	TrkA-C domain; Region: TrkA_C; pfam02080
1267753010031	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
1267753010032	putative RNA binding site [nucleotide binding]; other site
1267753010033	16S rRNA methyltransferase B; Provisional; Region: PRK10901
1267753010034	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753010035	S-adenosylmethionine binding site [chemical binding]; other site
1267753010036	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1267753010037	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1267753010038	putative active site [active]
1267753010039	substrate binding site [chemical binding]; other site
1267753010040	putative cosubstrate binding site; other site
1267753010041	catalytic site [active]
1267753010042	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1267753010043	substrate binding site [chemical binding]; other site
1267753010044	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1267753010045	active site
1267753010046	catalytic residues [active]
1267753010047	metal binding site [ion binding]; metal-binding site
1267753010048	hypothetical protein; Provisional; Region: PRK10736
1267753010049	DNA protecting protein DprA; Region: dprA; TIGR00732
1267753010050	hypothetical protein; Validated; Region: PRK03430
1267753010051	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1267753010052	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
1267753010053	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1267753010054	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1267753010055	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
1267753010056	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1267753010057	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1267753010058	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1267753010059	shikimate binding site; other site
1267753010060	NAD(P) binding site [chemical binding]; other site
1267753010061	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
1267753010062	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1267753010063	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1267753010064	trimer interface [polypeptide binding]; other site
1267753010065	putative metal binding site [ion binding]; other site
1267753010066	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
1267753010067	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
1267753010068	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753010069	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753010070	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
1267753010071	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753010072	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
1267753010073	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1267753010074	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1267753010075	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1267753010076	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753010077	metal binding site [ion binding]; metal-binding site
1267753010078	active site
1267753010079	I-site; other site
1267753010080	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753010081	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
1267753010082	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
1267753010083	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753010084	DNA methylase; Region: N6_N4_Mtase; pfam01555
1267753010085	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
1267753010086	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
1267753010087	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
1267753010088	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1267753010089	FMN binding site [chemical binding]; other site
1267753010090	active site
1267753010091	catalytic residues [active]
1267753010092	substrate binding site [chemical binding]; other site
1267753010093	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
1267753010094	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1267753010095	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
1267753010096	Na binding site [ion binding]; other site
1267753010097	hypothetical protein; Provisional; Region: PRK10633
1267753010098	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1267753010099	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1267753010100	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1267753010101	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1267753010102	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1267753010103	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1267753010104	carboxyltransferase (CT) interaction site; other site
1267753010105	biotinylation site [posttranslational modification]; other site
1267753010106	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
1267753010107	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1267753010108	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1267753010109	Moco binding site; other site
1267753010110	metal coordination site [ion binding]; other site
1267753010111	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
1267753010112	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1267753010113	NADP binding site [chemical binding]; other site
1267753010114	dimer interface [polypeptide binding]; other site
1267753010115	regulatory protein CsrD; Provisional; Region: PRK11059
1267753010116	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753010117	metal binding site [ion binding]; metal-binding site
1267753010118	active site
1267753010119	I-site; other site
1267753010120	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753010121	rod shape-determining protein MreB; Provisional; Region: PRK13927
1267753010122	MreB and similar proteins; Region: MreB_like; cd10225
1267753010123	nucleotide binding site [chemical binding]; other site
1267753010124	Mg binding site [ion binding]; other site
1267753010125	putative protofilament interaction site [polypeptide binding]; other site
1267753010126	RodZ interaction site [polypeptide binding]; other site
1267753010127	rod shape-determining protein MreC; Region: mreC; TIGR00219
1267753010128	rod shape-determining protein MreC; Region: MreC; pfam04085
1267753010129	rod shape-determining protein MreD; Provisional; Region: PRK11060
1267753010130	Maf-like protein; Region: Maf; pfam02545
1267753010131	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1267753010132	active site
1267753010133	dimer interface [polypeptide binding]; other site
1267753010134	ribonuclease G; Provisional; Region: PRK11712
1267753010135	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1267753010136	homodimer interface [polypeptide binding]; other site
1267753010137	oligonucleotide binding site [chemical binding]; other site
1267753010138	hypothetical protein; Provisional; Region: PRK10899
1267753010139	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1267753010140	protease TldD; Provisional; Region: tldD; PRK10735
1267753010141	transcriptional regulator; Provisional; Region: PRK10632
1267753010142	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753010143	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1267753010144	putative effector binding pocket; other site
1267753010145	dimerization interface [polypeptide binding]; other site
1267753010146	efflux system membrane protein; Provisional; Region: PRK11594
1267753010147	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
1267753010148	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753010149	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753010150	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
1267753010151	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1267753010152	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
1267753010153	RNAase interaction site [polypeptide binding]; other site
1267753010154	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753010155	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
1267753010156	arginine repressor; Provisional; Region: PRK05066
1267753010157	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1267753010158	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1267753010159	malate dehydrogenase; Provisional; Region: PRK05086
1267753010160	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
1267753010161	NAD binding site [chemical binding]; other site
1267753010162	dimerization interface [polypeptide binding]; other site
1267753010163	Substrate binding site [chemical binding]; other site
1267753010164	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1267753010165	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753010166	DNA-binding site [nucleotide binding]; DNA binding site
1267753010167	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1267753010168	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753010169	DNA-binding site [nucleotide binding]; DNA binding site
1267753010170	FCD domain; Region: FCD; pfam07729
1267753010171	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1267753010172	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1267753010173	transmembrane helices; other site
1267753010174	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
1267753010175	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
1267753010176	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
1267753010177	oxaloacetate decarboxylase; Provisional; Region: PRK14040
1267753010178	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1267753010179	active site
1267753010180	catalytic residues [active]
1267753010181	metal binding site [ion binding]; metal-binding site
1267753010182	homodimer binding site [polypeptide binding]; other site
1267753010183	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1267753010184	carboxyltransferase (CT) interaction site; other site
1267753010185	biotinylation site [posttranslational modification]; other site
1267753010186	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
1267753010187	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
1267753010188	serine endoprotease; Provisional; Region: PRK10898
1267753010189	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1267753010190	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1267753010191	serine endoprotease; Provisional; Region: PRK10139
1267753010192	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1267753010193	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1267753010194	protein binding site [polypeptide binding]; other site
1267753010195	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1267753010196	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
1267753010197	hypothetical protein; Provisional; Region: PRK11677
1267753010198	Predicted ATPase [General function prediction only]; Region: COG1485
1267753010199	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1267753010200	23S rRNA interface [nucleotide binding]; other site
1267753010201	L3 interface [polypeptide binding]; other site
1267753010202	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1267753010203	Family of unknown function (DUF695); Region: DUF695; pfam05117
1267753010204	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
1267753010205	stringent starvation protein A; Provisional; Region: sspA; PRK09481
1267753010206	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
1267753010207	C-terminal domain interface [polypeptide binding]; other site
1267753010208	putative GSH binding site (G-site) [chemical binding]; other site
1267753010209	dimer interface [polypeptide binding]; other site
1267753010210	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
1267753010211	dimer interface [polypeptide binding]; other site
1267753010212	N-terminal domain interface [polypeptide binding]; other site
1267753010213	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
1267753010214	transcriptional regulator NanR; Provisional; Region: PRK03837
1267753010215	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753010216	DNA-binding site [nucleotide binding]; DNA binding site
1267753010217	FCD domain; Region: FCD; pfam07729
1267753010218	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1267753010219	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1267753010220	inhibitor site; inhibition site
1267753010221	active site
1267753010222	dimer interface [polypeptide binding]; other site
1267753010223	catalytic residue [active]
1267753010224	putative sialic acid transporter; Provisional; Region: PRK03893
1267753010225	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753010226	putative substrate translocation pore; other site
1267753010227	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
1267753010228	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1267753010229	putative active site cavity [active]
1267753010230	N-acetylmannosamine kinase; Provisional; Region: PRK05082
1267753010231	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1267753010232	nucleotide binding site [chemical binding]; other site
1267753010233	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
1267753010234	cytosine deaminase; Provisional; Region: PRK09230
1267753010235	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1267753010236	active site
1267753010237	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1267753010238	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1267753010239	Na binding site [ion binding]; other site
1267753010240	putative substrate binding site [chemical binding]; other site
1267753010241	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1267753010242	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1267753010243	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
1267753010244	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1267753010245	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753010246	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1267753010247	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1267753010248	active site
1267753010249	dimer interface [polypeptide binding]; other site
1267753010250	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1267753010251	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1267753010252	active site
1267753010253	FMN binding site [chemical binding]; other site
1267753010254	substrate binding site [chemical binding]; other site
1267753010255	3Fe-4S cluster binding site [ion binding]; other site
1267753010256	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1267753010257	domain interface; other site
1267753010258	radical SAM protein, TIGR01212 family; Region: TIGR01212
1267753010259	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753010260	FeS/SAM binding site; other site
1267753010261	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
1267753010262	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1267753010263	putative active site [active]
1267753010264	heme pocket [chemical binding]; other site
1267753010265	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753010266	dimer interface [polypeptide binding]; other site
1267753010267	phosphorylation site [posttranslational modification]
1267753010268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753010269	ATP binding site [chemical binding]; other site
1267753010270	Mg2+ binding site [ion binding]; other site
1267753010271	G-X-G motif; other site
1267753010272	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753010273	active site
1267753010274	phosphorylation site [posttranslational modification]
1267753010275	intermolecular recognition site; other site
1267753010276	dimerization interface [polypeptide binding]; other site
1267753010277	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1267753010278	putative binding surface; other site
1267753010279	active site
1267753010280	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
1267753010281	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
1267753010282	conserved cys residue [active]
1267753010283	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
1267753010284	Transglycosylase; Region: Transgly; cl17702
1267753010285	hypothetical protein; Provisional; Region: PRK10345
1267753010286	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1267753010287	dimerization domain swap beta strand [polypeptide binding]; other site
1267753010288	regulatory protein interface [polypeptide binding]; other site
1267753010289	active site
1267753010290	regulatory phosphorylation site [posttranslational modification]; other site
1267753010291	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
1267753010292	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753010293	active site
1267753010294	phosphorylation site [posttranslational modification]
1267753010295	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1267753010296	30S subunit binding site; other site
1267753010297	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1267753010298	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1267753010299	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1267753010300	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1267753010301	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
1267753010302	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1267753010303	Walker A/P-loop; other site
1267753010304	ATP binding site [chemical binding]; other site
1267753010305	Q-loop/lid; other site
1267753010306	ABC transporter signature motif; other site
1267753010307	Walker B; other site
1267753010308	D-loop; other site
1267753010309	H-loop/switch region; other site
1267753010310	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
1267753010311	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
1267753010312	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
1267753010313	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1267753010314	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
1267753010315	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1267753010316	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
1267753010317	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1267753010318	putative active site [active]
1267753010319	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1267753010320	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
1267753010321	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1267753010322	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1267753010323	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
1267753010324	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1267753010325	Walker A/P-loop; other site
1267753010326	ATP binding site [chemical binding]; other site
1267753010327	Q-loop/lid; other site
1267753010328	ABC transporter signature motif; other site
1267753010329	Walker B; other site
1267753010330	D-loop; other site
1267753010331	H-loop/switch region; other site
1267753010332	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1267753010333	conserved hypothetical integral membrane protein; Region: TIGR00056
1267753010334	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1267753010335	mce related protein; Region: MCE; pfam02470
1267753010336	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
1267753010337	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1267753010338	anti sigma factor interaction site; other site
1267753010339	regulatory phosphorylation site [posttranslational modification]; other site
1267753010340	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
1267753010341	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1267753010342	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1267753010343	hinge; other site
1267753010344	active site
1267753010345	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
1267753010346	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1267753010347	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1267753010348	substrate binding pocket [chemical binding]; other site
1267753010349	chain length determination region; other site
1267753010350	substrate-Mg2+ binding site; other site
1267753010351	catalytic residues [active]
1267753010352	aspartate-rich region 1; other site
1267753010353	active site lid residues [active]
1267753010354	aspartate-rich region 2; other site
1267753010355	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1267753010356	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1267753010357	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1267753010358	EamA-like transporter family; Region: EamA; pfam00892
1267753010359	EamA-like transporter family; Region: EamA; pfam00892
1267753010360	GTPase CgtA; Reviewed; Region: obgE; PRK12298
1267753010361	GTP1/OBG; Region: GTP1_OBG; pfam01018
1267753010362	Obg GTPase; Region: Obg; cd01898
1267753010363	G1 box; other site
1267753010364	GTP/Mg2+ binding site [chemical binding]; other site
1267753010365	Switch I region; other site
1267753010366	G2 box; other site
1267753010367	G3 box; other site
1267753010368	Switch II region; other site
1267753010369	G4 box; other site
1267753010370	G5 box; other site
1267753010371	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
1267753010372	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
1267753010373	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1267753010374	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1267753010375	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1267753010376	RNA-binding protein YhbY; Provisional; Region: PRK10343
1267753010377	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
1267753010378	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753010379	S-adenosylmethionine binding site [chemical binding]; other site
1267753010380	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
1267753010381	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753010382	Walker A motif; other site
1267753010383	ATP binding site [chemical binding]; other site
1267753010384	Walker B motif; other site
1267753010385	arginine finger; other site
1267753010386	Peptidase family M41; Region: Peptidase_M41; pfam01434
1267753010387	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1267753010388	dihydropteroate synthase; Region: DHPS; TIGR01496
1267753010389	substrate binding pocket [chemical binding]; other site
1267753010390	dimer interface [polypeptide binding]; other site
1267753010391	inhibitor binding site; inhibition site
1267753010392	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
1267753010393	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1267753010394	active site
1267753010395	substrate binding site [chemical binding]; other site
1267753010396	metal binding site [ion binding]; metal-binding site
1267753010397	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1267753010398	argininosuccinate synthase; Validated; Region: PRK05370
1267753010399	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1267753010400	Sm and related proteins; Region: Sm_like; cl00259
1267753010401	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1267753010402	putative oligomer interface [polypeptide binding]; other site
1267753010403	putative RNA binding site [nucleotide binding]; other site
1267753010404	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
1267753010405	NusA N-terminal domain; Region: NusA_N; pfam08529
1267753010406	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1267753010407	RNA binding site [nucleotide binding]; other site
1267753010408	homodimer interface [polypeptide binding]; other site
1267753010409	NusA-like KH domain; Region: KH_5; pfam13184
1267753010410	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1267753010411	G-X-X-G motif; other site
1267753010412	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1267753010413	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
1267753010414	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1267753010415	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
1267753010416	translation initiation factor IF-2; Region: IF-2; TIGR00487
1267753010417	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1267753010418	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1267753010419	G1 box; other site
1267753010420	putative GEF interaction site [polypeptide binding]; other site
1267753010421	GTP/Mg2+ binding site [chemical binding]; other site
1267753010422	Switch I region; other site
1267753010423	G2 box; other site
1267753010424	G3 box; other site
1267753010425	Switch II region; other site
1267753010426	G4 box; other site
1267753010427	G5 box; other site
1267753010428	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1267753010429	Translation-initiation factor 2; Region: IF-2; pfam11987
1267753010430	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1267753010431	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1267753010432	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
1267753010433	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1267753010434	RNA binding site [nucleotide binding]; other site
1267753010435	active site
1267753010436	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
1267753010437	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1267753010438	16S/18S rRNA binding site [nucleotide binding]; other site
1267753010439	S13e-L30e interaction site [polypeptide binding]; other site
1267753010440	25S rRNA binding site [nucleotide binding]; other site
1267753010441	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1267753010442	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1267753010443	RNase E interface [polypeptide binding]; other site
1267753010444	trimer interface [polypeptide binding]; other site
1267753010445	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1267753010446	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1267753010447	RNase E interface [polypeptide binding]; other site
1267753010448	trimer interface [polypeptide binding]; other site
1267753010449	active site
1267753010450	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1267753010451	putative nucleic acid binding region [nucleotide binding]; other site
1267753010452	G-X-X-G motif; other site
1267753010453	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1267753010454	RNA binding site [nucleotide binding]; other site
1267753010455	domain interface; other site
1267753010456	lipoprotein NlpI; Provisional; Region: PRK11189
1267753010457	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1267753010458	binding surface
1267753010459	TPR motif; other site
1267753010460	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1267753010461	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1267753010462	ATP binding site [chemical binding]; other site
1267753010463	Mg++ binding site [ion binding]; other site
1267753010464	motif III; other site
1267753010465	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753010466	nucleotide binding region [chemical binding]; other site
1267753010467	ATP-binding site [chemical binding]; other site
1267753010468	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
1267753010469	putative RNA binding site [nucleotide binding]; other site
1267753010470	tryptophan permease; Provisional; Region: PRK10483
1267753010471	aromatic amino acid transport protein; Region: araaP; TIGR00837
1267753010472	hypothetical protein; Provisional; Region: PRK10508
1267753010473	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1267753010474	putative protease; Provisional; Region: PRK15447
1267753010475	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1267753010476	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1267753010477	Peptidase family U32; Region: Peptidase_U32; pfam01136
1267753010478	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
1267753010479	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1267753010480	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753010481	Coenzyme A binding pocket [chemical binding]; other site
1267753010482	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1267753010483	GIY-YIG motif/motif A; other site
1267753010484	putative active site [active]
1267753010485	putative metal binding site [ion binding]; other site
1267753010486	hypothetical protein; Provisional; Region: PRK03467
1267753010487	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1267753010488	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1267753010489	proposed catalytic triad [active]
1267753010490	conserved cys residue [active]
1267753010491	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1267753010492	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1267753010493	NAD binding site [chemical binding]; other site
1267753010494	active site
1267753010495	outer membrane lipoprotein; Provisional; Region: PRK11023
1267753010496	BON domain; Region: BON; pfam04972
1267753010497	BON domain; Region: BON; pfam04972
1267753010498	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1267753010499	dimer interface [polypeptide binding]; other site
1267753010500	active site
1267753010501	TIGR00252 family protein; Region: TIGR00252
1267753010502	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1267753010503	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
1267753010504	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
1267753010505	putative ligand binding site [chemical binding]; other site
1267753010506	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
1267753010507	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1267753010508	putative SAM binding site [chemical binding]; other site
1267753010509	putative homodimer interface [polypeptide binding]; other site
1267753010510	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753010511	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1267753010512	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753010513	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
1267753010514	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
1267753010515	putative NAD(P) binding site [chemical binding]; other site
1267753010516	catalytic Zn binding site [ion binding]; other site
1267753010517	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
1267753010518	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
1267753010519	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
1267753010520	active site
1267753010521	P-loop; other site
1267753010522	phosphorylation site [posttranslational modification]
1267753010523	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753010524	active site
1267753010525	phosphorylation site [posttranslational modification]
1267753010526	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
1267753010527	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753010528	active site
1267753010529	phosphorylation site [posttranslational modification]
1267753010530	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1267753010531	dimerization domain swap beta strand [polypeptide binding]; other site
1267753010532	regulatory protein interface [polypeptide binding]; other site
1267753010533	active site
1267753010534	regulatory phosphorylation site [posttranslational modification]; other site
1267753010535	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
1267753010536	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1267753010537	active site
1267753010538	P-loop; other site
1267753010539	phosphorylation site [posttranslational modification]
1267753010540	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1267753010541	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1267753010542	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1267753010543	putative substrate binding site [chemical binding]; other site
1267753010544	putative ATP binding site [chemical binding]; other site
1267753010545	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1267753010546	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1267753010547	intersubunit interface [polypeptide binding]; other site
1267753010548	active site
1267753010549	zinc binding site [ion binding]; other site
1267753010550	Na+ binding site [ion binding]; other site
1267753010551	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753010552	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1267753010553	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753010554	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1267753010555	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1267753010556	substrate binding site [chemical binding]; other site
1267753010557	ATP binding site [chemical binding]; other site
1267753010558	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1267753010559	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1267753010560	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1267753010561	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
1267753010562	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
1267753010563	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1267753010564	glycerate kinase I; Provisional; Region: PRK10342
1267753010565	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
1267753010566	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753010567	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
1267753010568	putative substrate binding pocket [chemical binding]; other site
1267753010569	putative dimerization interface [polypeptide binding]; other site
1267753010570	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
1267753010571	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1267753010572	tetramer interface [polypeptide binding]; other site
1267753010573	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753010574	catalytic residue [active]
1267753010575	threonine/serine transporter TdcC; Provisional; Region: PRK13629
1267753010576	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1267753010577	propionate/acetate kinase; Provisional; Region: PRK12379
1267753010578	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
1267753010579	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1267753010580	Pyruvate formate lyase 1; Region: PFL1; cd01678
1267753010581	coenzyme A binding site [chemical binding]; other site
1267753010582	active site
1267753010583	catalytic residues [active]
1267753010584	glycine loop; other site
1267753010585	L-serine dehydratase TdcG; Provisional; Region: PRK15040
1267753010586	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1267753010587	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1267753010588	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1267753010589	serine transporter; Region: stp; TIGR00814
1267753010590	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
1267753010591	Pirin-related protein [General function prediction only]; Region: COG1741
1267753010592	Pirin; Region: Pirin; pfam02678
1267753010593	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753010594	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
1267753010595	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1267753010596	dimerization interface [polypeptide binding]; other site
1267753010597	Predicted membrane protein [Function unknown]; Region: COG3152
1267753010598	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
1267753010599	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
1267753010600	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
1267753010601	putative dimer interface [polypeptide binding]; other site
1267753010602	N-terminal domain interface [polypeptide binding]; other site
1267753010603	putative substrate binding pocket (H-site) [chemical binding]; other site
1267753010604	Predicted membrane protein [Function unknown]; Region: COG2259
1267753010605	YqjK-like protein; Region: YqjK; pfam13997
1267753010606	Predicted membrane protein [Function unknown]; Region: COG5393
1267753010607	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
1267753010608	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1267753010609	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
1267753010610	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1267753010611	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1267753010612	serine/threonine transporter SstT; Provisional; Region: PRK13628
1267753010613	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1267753010614	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1267753010615	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1267753010616	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1267753010617	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1267753010618	putative active site [active]
1267753010619	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1267753010620	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
1267753010621	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753010622	S-adenosylmethionine binding site [chemical binding]; other site
1267753010623	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1267753010624	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
1267753010625	active site
1267753010626	FMN binding site [chemical binding]; other site
1267753010627	2,4-decadienoyl-CoA binding site; other site
1267753010628	catalytic residue [active]
1267753010629	4Fe-4S cluster binding site [ion binding]; other site
1267753010630	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
1267753010631	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1267753010632	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
1267753010633	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1267753010634	inhibitor-cofactor binding pocket; inhibition site
1267753010635	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753010636	catalytic residue [active]
1267753010637	PAS fold; Region: PAS_3; pfam08447
1267753010638	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1267753010639	putative active site [active]
1267753010640	heme pocket [chemical binding]; other site
1267753010641	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1267753010642	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1267753010643	dimer interface [polypeptide binding]; other site
1267753010644	putative CheW interface [polypeptide binding]; other site
1267753010645	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1267753010646	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753010647	dimerization interface [polypeptide binding]; other site
1267753010648	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1267753010649	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1267753010650	dimer interface [polypeptide binding]; other site
1267753010651	putative CheW interface [polypeptide binding]; other site
1267753010652	Predicted transcriptional regulators [Transcription]; Region: COG1695
1267753010653	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1267753010654	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
1267753010655	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
1267753010656	FAD binding pocket [chemical binding]; other site
1267753010657	FAD binding motif [chemical binding]; other site
1267753010658	phosphate binding motif [ion binding]; other site
1267753010659	NAD binding pocket [chemical binding]; other site
1267753010660	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
1267753010661	active site
1267753010662	SUMO-1 interface [polypeptide binding]; other site
1267753010663	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1267753010664	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1267753010665	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1267753010666	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
1267753010667	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1267753010668	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1267753010669	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1267753010670	DNA binding residues [nucleotide binding]
1267753010671	DNA primase; Validated; Region: dnaG; PRK05667
1267753010672	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1267753010673	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1267753010674	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1267753010675	active site
1267753010676	metal binding site [ion binding]; metal-binding site
1267753010677	interdomain interaction site; other site
1267753010678	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1267753010679	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
1267753010680	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1267753010681	UGMP family protein; Validated; Region: PRK09604
1267753010682	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1267753010683	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1267753010684	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1267753010685	homooctamer interface [polypeptide binding]; other site
1267753010686	active site
1267753010687	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1267753010688	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
1267753010689	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1267753010690	active site
1267753010691	NTP binding site [chemical binding]; other site
1267753010692	metal binding triad [ion binding]; metal-binding site
1267753010693	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1267753010694	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1267753010695	Zn2+ binding site [ion binding]; other site
1267753010696	Mg2+ binding site [ion binding]; other site
1267753010697	SH3 domain-containing protein; Provisional; Region: PRK10884
1267753010698	Bacterial SH3 domain homologues; Region: SH3b; smart00287
1267753010699	Uncharacterized conserved protein [Function unknown]; Region: COG3025
1267753010700	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
1267753010701	putative active site [active]
1267753010702	putative metal binding residues [ion binding]; other site
1267753010703	signature motif; other site
1267753010704	putative triphosphate binding site [ion binding]; other site
1267753010705	CHAD domain; Region: CHAD; pfam05235
1267753010706	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
1267753010707	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1267753010708	metal binding triad; other site
1267753010709	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1267753010710	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1267753010711	metal binding triad; other site
1267753010712	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
1267753010713	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
1267753010714	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1267753010715	putative ribose interaction site [chemical binding]; other site
1267753010716	putative ADP binding site [chemical binding]; other site
1267753010717	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1267753010718	active site
1267753010719	nucleotide binding site [chemical binding]; other site
1267753010720	HIGH motif; other site
1267753010721	KMSKS motif; other site
1267753010722	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1267753010723	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1267753010724	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
1267753010725	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
1267753010726	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
1267753010727	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
1267753010728	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
1267753010729	putative disulfide oxidoreductase; Provisional; Region: PRK04307
1267753010730	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1267753010731	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1267753010732	catalytic residues [active]
1267753010733	hinge region; other site
1267753010734	alpha helical domain; other site
1267753010735	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1267753010736	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
1267753010737	zinc transporter ZupT; Provisional; Region: PRK04201
1267753010738	ZIP Zinc transporter; Region: Zip; pfam02535
1267753010739	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1267753010740	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1267753010741	putative active site [active]
1267753010742	metal binding site [ion binding]; metal-binding site
1267753010743	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1267753010744	hypothetical protein; Provisional; Region: PRK11653
1267753010745	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
1267753010746	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
1267753010747	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1267753010748	dimer interface [polypeptide binding]; other site
1267753010749	ADP-ribose binding site [chemical binding]; other site
1267753010750	active site
1267753010751	nudix motif; other site
1267753010752	metal binding site [ion binding]; metal-binding site
1267753010753	putative dehydrogenase; Provisional; Region: PRK11039
1267753010754	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
1267753010755	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1267753010756	active site
1267753010757	metal binding site [ion binding]; metal-binding site
1267753010758	hexamer interface [polypeptide binding]; other site
1267753010759	esterase YqiA; Provisional; Region: PRK11071
1267753010760	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
1267753010761	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753010762	ATP binding site [chemical binding]; other site
1267753010763	Mg2+ binding site [ion binding]; other site
1267753010764	G-X-G motif; other site
1267753010765	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1267753010766	anchoring element; other site
1267753010767	dimer interface [polypeptide binding]; other site
1267753010768	ATP binding site [chemical binding]; other site
1267753010769	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1267753010770	active site
1267753010771	metal binding site [ion binding]; metal-binding site
1267753010772	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1267753010773	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1267753010774	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1267753010775	sensor protein QseC; Provisional; Region: PRK10337
1267753010776	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753010777	dimer interface [polypeptide binding]; other site
1267753010778	phosphorylation site [posttranslational modification]
1267753010779	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753010780	ATP binding site [chemical binding]; other site
1267753010781	Mg2+ binding site [ion binding]; other site
1267753010782	G-X-G motif; other site
1267753010783	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
1267753010784	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753010785	active site
1267753010786	phosphorylation site [posttranslational modification]
1267753010787	intermolecular recognition site; other site
1267753010788	dimerization interface [polypeptide binding]; other site
1267753010789	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753010790	DNA binding site [nucleotide binding]
1267753010791	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
1267753010792	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
1267753010793	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1267753010794	CAP-like domain; other site
1267753010795	active site
1267753010796	primary dimer interface [polypeptide binding]; other site
1267753010797	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1267753010798	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
1267753010799	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1267753010800	putative acyl-acceptor binding pocket; other site
1267753010801	FtsI repressor; Provisional; Region: PRK10883
1267753010802	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1267753010803	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1267753010804	YARHG domain; Region: YARHG; pfam13308
1267753010805	hypothetical protein; Provisional; Region: PRK01254
1267753010806	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1267753010807	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1267753010808	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1267753010809	nucleotide binding site/active site [active]
1267753010810	catalytic residue [active]
1267753010811	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1267753010812	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
1267753010813	transmembrane helices; other site
1267753010814	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1267753010815	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1267753010816	active site
1267753010817	catalytic tetrad [active]
1267753010818	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1267753010819	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1267753010820	dimer interface [polypeptide binding]; other site
1267753010821	active site
1267753010822	metal binding site [ion binding]; metal-binding site
1267753010823	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1267753010824	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1267753010825	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753010826	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753010827	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1267753010828	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1267753010829	cystathionine beta-lyase; Provisional; Region: PRK08114
1267753010830	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1267753010831	homodimer interface [polypeptide binding]; other site
1267753010832	substrate-cofactor binding pocket; other site
1267753010833	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753010834	catalytic residue [active]
1267753010835	biopolymer transport protein ExbB; Provisional; Region: PRK10414
1267753010836	biopolymer transport protein ExbD; Provisional; Region: PRK11267
1267753010837	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1267753010838	oxidoreductase; Provisional; Region: PRK07985
1267753010839	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1267753010840	NAD binding site [chemical binding]; other site
1267753010841	metal binding site [ion binding]; metal-binding site
1267753010842	active site
1267753010843	hypothetical protein; Provisional; Region: PRK05208
1267753010844	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
1267753010845	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753010846	dimerization interface [polypeptide binding]; other site
1267753010847	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1267753010848	dimer interface [polypeptide binding]; other site
1267753010849	putative CheW interface [polypeptide binding]; other site
1267753010850	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
1267753010851	hydrogenase 2 small subunit; Provisional; Region: PRK10468
1267753010852	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1267753010853	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1267753010854	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
1267753010855	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1267753010856	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
1267753010857	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1267753010858	hydrogenase 2 large subunit; Provisional; Region: PRK10467
1267753010859	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1267753010860	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1267753010861	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1267753010862	putative substrate-binding site; other site
1267753010863	nickel binding site [ion binding]; other site
1267753010864	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
1267753010865	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1267753010866	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
1267753010867	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
1267753010868	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
1267753010869	putative ligand binding residues [chemical binding]; other site
1267753010870	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1267753010871	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1267753010872	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
1267753010873	putative S-transferase; Provisional; Region: PRK11752
1267753010874	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1267753010875	C-terminal domain interface [polypeptide binding]; other site
1267753010876	GSH binding site (G-site) [chemical binding]; other site
1267753010877	dimer interface [polypeptide binding]; other site
1267753010878	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
1267753010879	dimer interface [polypeptide binding]; other site
1267753010880	N-terminal domain interface [polypeptide binding]; other site
1267753010881	active site
1267753010882	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
1267753010883	CHAP domain; Region: CHAP; pfam05257
1267753010884	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1267753010885	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1267753010886	dimer interface [polypeptide binding]; other site
1267753010887	putative CheW interface [polypeptide binding]; other site
1267753010888	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1267753010889	Glucuronate isomerase; Region: UxaC; pfam02614
1267753010890	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1267753010891	D-mannonate oxidoreductase; Provisional; Region: PRK15037
1267753010892	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1267753010893	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1267753010894	mannonate dehydratase; Provisional; Region: PRK03906
1267753010895	mannonate dehydratase; Region: uxuA; TIGR00695
1267753010896	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753010897	D-galactonate transporter; Region: 2A0114; TIGR00893
1267753010898	putative substrate translocation pore; other site
1267753010899	putative outer membrane porin protein; Provisional; Region: PRK11379
1267753010900	glucuronide transporter; Provisional; Region: PRK09848
1267753010901	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753010902	putative substrate translocation pore; other site
1267753010903	beta-D-glucuronidase; Provisional; Region: PRK10150
1267753010904	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1267753010905	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1267753010906	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1267753010907	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1267753010908	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1267753010909	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1267753010910	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
1267753010911	putative active site [active]
1267753010912	catalytic triad [active]
1267753010913	putative dimer interface [polypeptide binding]; other site
1267753010914	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
1267753010915	active site
1267753010916	catalytic site [active]
1267753010917	Zn binding site [ion binding]; other site
1267753010918	tetramer interface [polypeptide binding]; other site
1267753010919	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
1267753010920	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
1267753010921	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
1267753010922	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1267753010923	NAD(P) binding site [chemical binding]; other site
1267753010924	catalytic residues [active]
1267753010925	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1267753010926	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1267753010927	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
1267753010928	Amino acid permease; Region: AA_permease_2; pfam13520
1267753010929	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
1267753010930	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1267753010931	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753010932	DNA binding residues [nucleotide binding]
1267753010933	dimerization interface [polypeptide binding]; other site
1267753010934	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
1267753010935	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753010936	FeS/SAM binding site; other site
1267753010937	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1267753010938	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
1267753010939	Sulfatase; Region: Sulfatase; pfam00884
1267753010940	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
1267753010941	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753010942	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
1267753010943	putative dimerization interface [polypeptide binding]; other site
1267753010944	putative substrate binding pocket [chemical binding]; other site
1267753010945	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
1267753010946	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
1267753010947	putative active site [active]
1267753010948	putative catalytic site [active]
1267753010949	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
1267753010950	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
1267753010951	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
1267753010952	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
1267753010953	dimer interface [polypeptide binding]; other site
1267753010954	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1267753010955	metal binding site [ion binding]; metal-binding site
1267753010956	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
1267753010957	ornithine decarboxylase; Provisional; Region: PRK13578
1267753010958	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1267753010959	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1267753010960	homodimer interface [polypeptide binding]; other site
1267753010961	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753010962	catalytic residue [active]
1267753010963	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1267753010964	nucleoside transporter; Region: 2A0110; TIGR00889
1267753010965	murein transglycosylase C; Provisional; Region: mltC; PRK11671
1267753010966	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
1267753010967	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1267753010968	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1267753010969	catalytic residue [active]
1267753010970	oxidative damage protection protein; Provisional; Region: PRK05408
1267753010971	adenine DNA glycosylase; Provisional; Region: PRK10880
1267753010972	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1267753010973	minor groove reading motif; other site
1267753010974	helix-hairpin-helix signature motif; other site
1267753010975	substrate binding pocket [chemical binding]; other site
1267753010976	active site
1267753010977	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1267753010978	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1267753010979	DNA binding and oxoG recognition site [nucleotide binding]
1267753010980	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
1267753010981	hypothetical protein; Provisional; Region: PRK11702
1267753010982	hypothetical protein; Provisional; Region: PRK10626
1267753010983	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1267753010984	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
1267753010985	homodimer interface [polypeptide binding]; other site
1267753010986	active site
1267753010987	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
1267753010988	HemN family oxidoreductase; Provisional; Region: PRK05660
1267753010989	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753010990	FeS/SAM binding site; other site
1267753010991	HemN C-terminal domain; Region: HemN_C; pfam06969
1267753010992	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1267753010993	active site
1267753010994	dimerization interface [polypeptide binding]; other site
1267753010995	hypothetical protein; Validated; Region: PRK05090
1267753010996	YGGT family; Region: YGGT; pfam02325
1267753010997	YGGT family; Region: YGGT; pfam02325
1267753010998	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
1267753010999	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1267753011000	catalytic residue [active]
1267753011001	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1267753011002	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
1267753011003	Walker A motif; other site
1267753011004	ATP binding site [chemical binding]; other site
1267753011005	Walker B motif; other site
1267753011006	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
1267753011007	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1267753011008	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1267753011009	hypothetical protein; Validated; Region: PRK00228
1267753011010	glutathione synthetase; Provisional; Region: PRK05246
1267753011011	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
1267753011012	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
1267753011013	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1267753011014	RNA methyltransferase, RsmE family; Region: TIGR00046
1267753011015	DNA-specific endonuclease I; Provisional; Region: PRK15137
1267753011016	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
1267753011017	hypothetical protein; Provisional; Region: PRK04860
1267753011018	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
1267753011019	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1267753011020	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011021	putative substrate translocation pore; other site
1267753011022	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011023	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1267753011024	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1267753011025	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1267753011026	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1267753011027	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
1267753011028	Virulence promoting factor; Region: YqgB; pfam11036
1267753011029	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1267753011030	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1267753011031	dimer interface [polypeptide binding]; other site
1267753011032	active site
1267753011033	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1267753011034	catalytic residues [active]
1267753011035	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1267753011036	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
1267753011037	agmatinase; Region: agmatinase; TIGR01230
1267753011038	oligomer interface [polypeptide binding]; other site
1267753011039	putative active site [active]
1267753011040	Mn binding site [ion binding]; other site
1267753011041	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1267753011042	transketolase; Reviewed; Region: PRK12753
1267753011043	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1267753011044	TPP-binding site [chemical binding]; other site
1267753011045	dimer interface [polypeptide binding]; other site
1267753011046	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1267753011047	PYR/PP interface [polypeptide binding]; other site
1267753011048	dimer interface [polypeptide binding]; other site
1267753011049	TPP binding site [chemical binding]; other site
1267753011050	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1267753011051	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753011052	active site
1267753011053	phosphorylation site [posttranslational modification]
1267753011054	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
1267753011055	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1267753011056	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1267753011057	active site
1267753011058	P-loop; other site
1267753011059	phosphorylation site [posttranslational modification]
1267753011060	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
1267753011061	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1267753011062	putative NAD(P) binding site [chemical binding]; other site
1267753011063	catalytic Zn binding site [ion binding]; other site
1267753011064	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1267753011065	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1267753011066	putative active site [active]
1267753011067	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
1267753011068	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
1267753011069	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
1267753011070	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1267753011071	active site
1267753011072	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1267753011073	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1267753011074	Walker A/P-loop; other site
1267753011075	ATP binding site [chemical binding]; other site
1267753011076	Q-loop/lid; other site
1267753011077	ABC transporter signature motif; other site
1267753011078	Walker B; other site
1267753011079	D-loop; other site
1267753011080	H-loop/switch region; other site
1267753011081	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1267753011082	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1267753011083	Walker A/P-loop; other site
1267753011084	ATP binding site [chemical binding]; other site
1267753011085	Q-loop/lid; other site
1267753011086	ABC transporter signature motif; other site
1267753011087	Walker B; other site
1267753011088	D-loop; other site
1267753011089	H-loop/switch region; other site
1267753011090	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1267753011091	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
1267753011092	trimer interface [polypeptide binding]; other site
1267753011093	putative Zn binding site [ion binding]; other site
1267753011094	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
1267753011095	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1267753011096	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1267753011097	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1267753011098	Phosphoglycerate kinase; Region: PGK; pfam00162
1267753011099	substrate binding site [chemical binding]; other site
1267753011100	hinge regions; other site
1267753011101	ADP binding site [chemical binding]; other site
1267753011102	catalytic site [active]
1267753011103	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1267753011104	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1267753011105	active site
1267753011106	intersubunit interface [polypeptide binding]; other site
1267753011107	zinc binding site [ion binding]; other site
1267753011108	Na+ binding site [ion binding]; other site
1267753011109	mechanosensitive channel MscS; Provisional; Region: PRK10334
1267753011110	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1267753011111	arginine exporter protein; Provisional; Region: PRK09304
1267753011112	Uncharacterized conserved protein [Function unknown]; Region: COG2968
1267753011113	oxidative stress defense protein; Provisional; Region: PRK11087
1267753011114	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
1267753011115	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753011116	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
1267753011117	putative dimerization interface [polypeptide binding]; other site
1267753011118	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1267753011119	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1267753011120	active site
1267753011121	dimer interface [polypeptide binding]; other site
1267753011122	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
1267753011123	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
1267753011124	ligand binding site [chemical binding]; other site
1267753011125	NAD binding site [chemical binding]; other site
1267753011126	tetramer interface [polypeptide binding]; other site
1267753011127	catalytic site [active]
1267753011128	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1267753011129	L-serine binding site [chemical binding]; other site
1267753011130	ACT domain interface; other site
1267753011131	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
1267753011132	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1267753011133	Z-ring-associated protein; Provisional; Region: PRK10972
1267753011134	hypothetical protein; Reviewed; Region: PRK01736
1267753011135	proline aminopeptidase P II; Provisional; Region: PRK10879
1267753011136	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
1267753011137	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1267753011138	active site
1267753011139	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
1267753011140	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1267753011141	oxidoreductase; Provisional; Region: PRK08013
1267753011142	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
1267753011143	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1267753011144	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1267753011145	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1267753011146	lipoyl attachment site [posttranslational modification]; other site
1267753011147	glycine dehydrogenase; Provisional; Region: PRK05367
1267753011148	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1267753011149	tetramer interface [polypeptide binding]; other site
1267753011150	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753011151	catalytic residue [active]
1267753011152	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1267753011153	tetramer interface [polypeptide binding]; other site
1267753011154	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753011155	catalytic residue [active]
1267753011156	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
1267753011157	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
1267753011158	beta-galactosidase; Region: BGL; TIGR03356
1267753011159	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
1267753011160	hemolysin; Provisional; Region: PRK15087
1267753011161	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1267753011162	putative global regulator; Reviewed; Region: PRK09559
1267753011163	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
1267753011164	hypothetical protein; Provisional; Region: PRK10878
1267753011165	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
1267753011166	flavodoxin FldB; Provisional; Region: PRK12359
1267753011167	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
1267753011168	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1267753011169	active site
1267753011170	Int/Topo IB signature motif; other site
1267753011171	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
1267753011172	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
1267753011173	dimerization domain [polypeptide binding]; other site
1267753011174	dimer interface [polypeptide binding]; other site
1267753011175	catalytic residues [active]
1267753011176	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
1267753011177	DHH family; Region: DHH; pfam01368
1267753011178	DHHA1 domain; Region: DHHA1; pfam02272
1267753011179	potential frameshift: common BLAST hit: gi|197363916|ref|YP_002143553.1| peptide chain release factor 2
1267753011180	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
1267753011181	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1267753011182	dimer interface [polypeptide binding]; other site
1267753011183	putative anticodon binding site; other site
1267753011184	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1267753011185	motif 1; other site
1267753011186	active site
1267753011187	motif 2; other site
1267753011188	motif 3; other site
1267753011189	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
1267753011190	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1267753011191	active site
1267753011192	metal binding site [ion binding]; metal-binding site
1267753011193	nudix motif; other site
1267753011194	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1267753011195	Peptidase family M23; Region: Peptidase_M23; pfam01551
1267753011196	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
1267753011197	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
1267753011198	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
1267753011199	hypothetical protein; Provisional; Region: PRK10316
1267753011200	YfdX protein; Region: YfdX; pfam10938
1267753011201	fimbrial protein StdA; Provisional; Region: PRK15210
1267753011202	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
1267753011203	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753011204	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753011205	PapC C-terminal domain; Region: PapC_C; pfam13953
1267753011206	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
1267753011207	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753011208	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753011209	Fimbrial protein; Region: Fimbrial; pfam00419
1267753011210	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
1267753011211	transcriptional activator SprB; Provisional; Region: PRK15320
1267753011212	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
1267753011213	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
1267753011214	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
1267753011215	putative metal binding site [ion binding]; other site
1267753011216	putative homodimer interface [polypeptide binding]; other site
1267753011217	putative homotetramer interface [polypeptide binding]; other site
1267753011218	putative homodimer-homodimer interface [polypeptide binding]; other site
1267753011219	putative allosteric switch controlling residues; other site
1267753011220	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1267753011221	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1267753011222	Predicted membrane protein [Function unknown]; Region: COG4125
1267753011223	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1267753011224	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
1267753011225	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753011226	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753011227	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1267753011228	dimerization interface [polypeptide binding]; other site
1267753011229	putative acyltransferase; Provisional; Region: PRK05790
1267753011230	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1267753011231	dimer interface [polypeptide binding]; other site
1267753011232	active site
1267753011233	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1267753011234	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
1267753011235	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1267753011236	NADP binding site [chemical binding]; other site
1267753011237	homodimer interface [polypeptide binding]; other site
1267753011238	active site
1267753011239	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
1267753011240	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011241	putative substrate translocation pore; other site
1267753011242	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011243	putative racemase; Provisional; Region: PRK10200
1267753011244	aspartate racemase; Region: asp_race; TIGR00035
1267753011245	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
1267753011246	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753011247	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1267753011248	dimerization interface [polypeptide binding]; other site
1267753011249	diaminopimelate decarboxylase; Provisional; Region: PRK11165
1267753011250	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1267753011251	active site
1267753011252	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1267753011253	substrate binding site [chemical binding]; other site
1267753011254	catalytic residues [active]
1267753011255	dimer interface [polypeptide binding]; other site
1267753011256	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1267753011257	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753011258	DNA binding site [nucleotide binding]
1267753011259	domain linker motif; other site
1267753011260	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1267753011261	dimerization interface (closed form) [polypeptide binding]; other site
1267753011262	ligand binding site [chemical binding]; other site
1267753011263	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
1267753011264	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753011265	DNA binding site [nucleotide binding]
1267753011266	domain linker motif; other site
1267753011267	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
1267753011268	dimerization interface (closed form) [polypeptide binding]; other site
1267753011269	ligand binding site [chemical binding]; other site
1267753011270	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
1267753011271	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1267753011272	putative acyl-acceptor binding pocket; other site
1267753011273	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
1267753011274	acyl-activating enzyme (AAE) consensus motif; other site
1267753011275	putative AMP binding site [chemical binding]; other site
1267753011276	lysophospholipid transporter LplT; Provisional; Region: PRK11195
1267753011277	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011278	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1267753011279	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1267753011280	active site
1267753011281	catalytic tetrad [active]
1267753011282	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1267753011283	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1267753011284	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
1267753011285	putative DNA-binding cleft [nucleotide binding]; other site
1267753011286	putative DNA clevage site; other site
1267753011287	molecular lever; other site
1267753011288	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1267753011289	putative active site [active]
1267753011290	Ap4A binding site [chemical binding]; other site
1267753011291	nudix motif; other site
1267753011292	putative metal binding site [ion binding]; other site
1267753011293	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
1267753011294	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1267753011295	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1267753011296	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1267753011297	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1267753011298	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1267753011299	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1267753011300	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1267753011301	dimerization interface [polypeptide binding]; other site
1267753011302	active site
1267753011303	hypothetical protein; Provisional; Region: PRK10506
1267753011304	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1267753011305	hypothetical protein; Provisional; Region: PRK10557
1267753011306	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
1267753011307	hypothetical protein; Provisional; Region: PRK11521
1267753011308	hypothetical protein; Provisional; Region: PRK10332
1267753011309	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
1267753011310	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
1267753011311	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
1267753011312	protease3; Provisional; Region: PRK15101
1267753011313	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1267753011314	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1267753011315	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1267753011316	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
1267753011317	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
1267753011318	AAA domain; Region: AAA_30; pfam13604
1267753011319	Family description; Region: UvrD_C_2; pfam13538
1267753011320	N-acetylglutamate synthase; Validated; Region: PRK05279
1267753011321	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
1267753011322	putative feedback inhibition sensing region; other site
1267753011323	putative nucleotide binding site [chemical binding]; other site
1267753011324	putative substrate binding site [chemical binding]; other site
1267753011325	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753011326	Coenzyme A binding pocket [chemical binding]; other site
1267753011327	AMIN domain; Region: AMIN; pfam11741
1267753011328	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1267753011329	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1267753011330	active site
1267753011331	metal binding site [ion binding]; metal-binding site
1267753011332	murein transglycosylase A; Provisional; Region: mltA; PRK11162
1267753011333	murein hydrolase B; Provisional; Region: PRK10760; cl17906
1267753011334	MltA specific insert domain; Region: MltA; pfam03562
1267753011335	3D domain; Region: 3D; pfam06725
1267753011336	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
1267753011337	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1267753011338	putative ATP binding site [chemical binding]; other site
1267753011339	putative substrate interface [chemical binding]; other site
1267753011340	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1267753011341	CsdA-binding activator; Provisional; Region: PRK15019
1267753011342	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1267753011343	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1267753011344	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1267753011345	catalytic residue [active]
1267753011346	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
1267753011347	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
1267753011348	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753011349	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
1267753011350	dimerization interface [polypeptide binding]; other site
1267753011351	substrate binding pocket [chemical binding]; other site
1267753011352	hypothetical protein; Provisional; Region: PRK10873
1267753011353	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
1267753011354	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1267753011355	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
1267753011356	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1267753011357	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753011358	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
1267753011359	L-fuculokinase; Provisional; Region: PRK10331
1267753011360	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1267753011361	nucleotide binding site [chemical binding]; other site
1267753011362	L-fucose isomerase; Provisional; Region: fucI; PRK10991
1267753011363	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
1267753011364	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1267753011365	trimer interface [polypeptide binding]; other site
1267753011366	substrate binding site [chemical binding]; other site
1267753011367	Mn binding site [ion binding]; other site
1267753011368	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1267753011369	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011370	putative substrate translocation pore; other site
1267753011371	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
1267753011372	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
1267753011373	intersubunit interface [polypeptide binding]; other site
1267753011374	active site
1267753011375	Zn2+ binding site [ion binding]; other site
1267753011376	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
1267753011377	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
1267753011378	dimer interface [polypeptide binding]; other site
1267753011379	active site
1267753011380	metal binding site [ion binding]; metal-binding site
1267753011381	flap endonuclease-like protein; Provisional; Region: PRK09482
1267753011382	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1267753011383	active site
1267753011384	metal binding site 1 [ion binding]; metal-binding site
1267753011385	putative 5' ssDNA interaction site; other site
1267753011386	metal binding site 3; metal-binding site
1267753011387	metal binding site 2 [ion binding]; metal-binding site
1267753011388	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1267753011389	putative DNA binding site [nucleotide binding]; other site
1267753011390	putative metal binding site [ion binding]; other site
1267753011391	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1267753011392	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1267753011393	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1267753011394	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1267753011395	serine transporter; Region: stp; TIGR00814
1267753011396	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1267753011397	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
1267753011398	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
1267753011399	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
1267753011400	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
1267753011401	SecY interacting protein Syd; Provisional; Region: PRK04968
1267753011402	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
1267753011403	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1267753011404	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
1267753011405	probable active site [active]
1267753011406	flavodoxin; Provisional; Region: PRK08105
1267753011407	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011408	D-galactonate transporter; Region: 2A0114; TIGR00893
1267753011409	putative substrate translocation pore; other site
1267753011410	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1267753011411	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1267753011412	active site
1267753011413	tetramer interface [polypeptide binding]; other site
1267753011414	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
1267753011415	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
1267753011416	active site
1267753011417	tetramer interface [polypeptide binding]; other site
1267753011418	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1267753011419	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
1267753011420	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
1267753011421	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753011422	dimerization interface [polypeptide binding]; other site
1267753011423	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753011424	dimer interface [polypeptide binding]; other site
1267753011425	phosphorylation site [posttranslational modification]
1267753011426	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753011427	ATP binding site [chemical binding]; other site
1267753011428	Mg2+ binding site [ion binding]; other site
1267753011429	G-X-G motif; other site
1267753011430	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
1267753011431	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753011432	active site
1267753011433	phosphorylation site [posttranslational modification]
1267753011434	intermolecular recognition site; other site
1267753011435	dimerization interface [polypeptide binding]; other site
1267753011436	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1267753011437	putative binding surface; other site
1267753011438	active site
1267753011439	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
1267753011440	TRAM domain; Region: TRAM; pfam01938
1267753011441	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753011442	S-adenosylmethionine binding site [chemical binding]; other site
1267753011443	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
1267753011444	HD domain; Region: HD_4; pfam13328
1267753011445	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1267753011446	synthetase active site [active]
1267753011447	NTP binding site [chemical binding]; other site
1267753011448	metal binding site [ion binding]; metal-binding site
1267753011449	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1267753011450	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1267753011451	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
1267753011452	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1267753011453	Fimbrial protein; Region: Fimbrial; cl01416
1267753011454	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1267753011455	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1267753011456	homodimer interface [polypeptide binding]; other site
1267753011457	metal binding site [ion binding]; metal-binding site
1267753011458	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1267753011459	homodimer interface [polypeptide binding]; other site
1267753011460	active site
1267753011461	putative chemical substrate binding site [chemical binding]; other site
1267753011462	metal binding site [ion binding]; metal-binding site
1267753011463	CTP synthetase; Validated; Region: pyrG; PRK05380
1267753011464	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1267753011465	Catalytic site [active]
1267753011466	active site
1267753011467	UTP binding site [chemical binding]; other site
1267753011468	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1267753011469	active site
1267753011470	putative oxyanion hole; other site
1267753011471	catalytic triad [active]
1267753011472	enolase; Provisional; Region: eno; PRK00077
1267753011473	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1267753011474	dimer interface [polypeptide binding]; other site
1267753011475	metal binding site [ion binding]; metal-binding site
1267753011476	substrate binding pocket [chemical binding]; other site
1267753011477	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1267753011478	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1267753011479	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
1267753011480	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1267753011481	active site
1267753011482	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
1267753011483	Flavodoxin; Region: Flavodoxin_1; pfam00258
1267753011484	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
1267753011485	FAD binding pocket [chemical binding]; other site
1267753011486	FAD binding motif [chemical binding]; other site
1267753011487	catalytic residues [active]
1267753011488	NAD binding pocket [chemical binding]; other site
1267753011489	phosphate binding motif [ion binding]; other site
1267753011490	beta-alpha-beta structure motif; other site
1267753011491	sulfite reductase subunit beta; Provisional; Region: PRK13504
1267753011492	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1267753011493	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1267753011494	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1267753011495	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1267753011496	Active Sites [active]
1267753011497	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
1267753011498	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1267753011499	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
1267753011500	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1267753011501	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
1267753011502	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1267753011503	metal binding site [ion binding]; metal-binding site
1267753011504	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1267753011505	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1267753011506	Active Sites [active]
1267753011507	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
1267753011508	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1267753011509	CysD dimerization site [polypeptide binding]; other site
1267753011510	G1 box; other site
1267753011511	putative GEF interaction site [polypeptide binding]; other site
1267753011512	GTP/Mg2+ binding site [chemical binding]; other site
1267753011513	Switch I region; other site
1267753011514	G2 box; other site
1267753011515	G3 box; other site
1267753011516	Switch II region; other site
1267753011517	G4 box; other site
1267753011518	G5 box; other site
1267753011519	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1267753011520	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1267753011521	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1267753011522	ligand-binding site [chemical binding]; other site
1267753011523	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
1267753011524	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
1267753011525	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1267753011526	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1267753011527	substrate binding site; other site
1267753011528	dimer interface; other site
1267753011529	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1267753011530	homotrimer interaction site [polypeptide binding]; other site
1267753011531	zinc binding site [ion binding]; other site
1267753011532	CDP-binding sites; other site
1267753011533	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1267753011534	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1267753011535	Permutation of conserved domain; other site
1267753011536	active site
1267753011537	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1267753011538	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1267753011539	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1267753011540	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753011541	S-adenosylmethionine binding site [chemical binding]; other site
1267753011542	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1267753011543	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1267753011544	Peptidase family M23; Region: Peptidase_M23; pfam01551
1267753011545	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
1267753011546	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1267753011547	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1267753011548	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1267753011549	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1267753011550	DNA binding residues [nucleotide binding]
1267753011551	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
1267753011552	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
1267753011553	Flavoprotein; Region: Flavoprotein; pfam02441
1267753011554	MarR family; Region: MarR_2; cl17246
1267753011555	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1267753011556	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1267753011557	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1267753011558	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753011559	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1267753011560	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1267753011561	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
1267753011562	putative aldolase; Validated; Region: PRK08130
1267753011563	intersubunit interface [polypeptide binding]; other site
1267753011564	active site
1267753011565	Zn2+ binding site [ion binding]; other site
1267753011566	hypothetical protein; Provisional; Region: PRK09989
1267753011567	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1267753011568	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
1267753011569	putative NAD(P) binding site [chemical binding]; other site
1267753011570	active site
1267753011571	putative substrate binding site [chemical binding]; other site
1267753011572	GntP family permease; Region: GntP_permease; pfam02447
1267753011573	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1267753011574	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753011575	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753011576	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
1267753011577	putative effector binding pocket; other site
1267753011578	dimerization interface [polypeptide binding]; other site
1267753011579	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011580	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1267753011581	putative substrate translocation pore; other site
1267753011582	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
1267753011583	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1267753011584	MutS domain I; Region: MutS_I; pfam01624
1267753011585	MutS domain II; Region: MutS_II; pfam05188
1267753011586	MutS domain III; Region: MutS_III; pfam05192
1267753011587	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1267753011588	Walker A/P-loop; other site
1267753011589	ATP binding site [chemical binding]; other site
1267753011590	Q-loop/lid; other site
1267753011591	ABC transporter signature motif; other site
1267753011592	Walker B; other site
1267753011593	D-loop; other site
1267753011594	H-loop/switch region; other site
1267753011595	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
1267753011596	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1267753011597	active site
1267753011598	metal binding site [ion binding]; metal-binding site
1267753011599	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1267753011600	InvH outer membrane lipoprotein; Region: InvH; pfam04741
1267753011601	transcriptional regulator InvF; Provisional; Region: PRK15340
1267753011602	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
1267753011603	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1267753011604	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
1267753011605	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1267753011606	type III secretion system regulator InvE; Provisional; Region: PRK15338
1267753011607	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
1267753011608	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
1267753011609	type III secretion system protein InvA; Provisional; Region: PRK15337
1267753011610	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
1267753011611	ATP synthase SpaL; Validated; Region: PRK08149
1267753011612	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1267753011613	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1267753011614	Walker A motif; other site
1267753011615	ATP binding site [chemical binding]; other site
1267753011616	Walker B motif; other site
1267753011617	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
1267753011618	antigen presentation protein SpaN; Provisional; Region: PRK15334
1267753011619	Surface presentation of antigens protein; Region: SPAN; pfam02510
1267753011620	type III secretion system protein SpaO; Validated; Region: PRK08158
1267753011621	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
1267753011622	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
1267753011623	type III secretion system protein SpaQ; Provisional; Region: PRK15333
1267753011624	type III secretion system protein SpaR; Provisional; Region: PRK15332
1267753011625	type III secretion system protein SpaS; Validated; Region: PRK08156
1267753011626	chaperone protein SicA; Provisional; Region: PRK15331
1267753011627	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1267753011628	Tetratricopeptide repeat; Region: TPR_3; pfam07720
1267753011629	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
1267753011630	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
1267753011631	cell invasion protein SipD; Provisional; Region: PRK15330
1267753011632	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
1267753011633	putative acyl carrier protein IacP; Validated; Region: PRK08172
1267753011634	chaperone protein SicP; Provisional; Region: PRK15329
1267753011635	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
1267753011636	SicP binding; Region: SicP-binding; pfam09119
1267753011637	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
1267753011638	switch II binding region; other site
1267753011639	Rac1 P-loop interaction site [polypeptide binding]; other site
1267753011640	GTP binding residues [chemical binding]; other site
1267753011641	switch I binding region; other site
1267753011642	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
1267753011643	active site
1267753011644	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1267753011645	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1267753011646	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1267753011647	catalytic residue [active]
1267753011648	invasion protein regulator; Provisional; Region: PRK12370
1267753011649	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753011650	DNA binding site [nucleotide binding]
1267753011651	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1267753011652	binding surface
1267753011653	TPR motif; other site
1267753011654	transcriptional regulator HilD; Provisional; Region: PRK15185
1267753011655	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753011656	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
1267753011657	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
1267753011658	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
1267753011659	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
1267753011660	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
1267753011661	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
1267753011662	invasion protein OrgA; Provisional; Region: PRK15323
1267753011663	invasion protein OrgB; Provisional; Region: PRK15322
1267753011664	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
1267753011665	transcriptional regulator SirC; Provisional; Region: PRK15044
1267753011666	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753011667	transcriptional activator SprB; Provisional; Region: PRK15320
1267753011668	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
1267753011669	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1267753011670	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1267753011671	ABC-ATPase subunit  interface; other site
1267753011672	dimer interface [polypeptide binding]; other site
1267753011673	putative PBP binding regions; other site
1267753011674	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1267753011675	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1267753011676	ABC-ATPase subunit  interface; other site
1267753011677	dimer interface [polypeptide binding]; other site
1267753011678	putative PBP binding regions; other site
1267753011679	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
1267753011680	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1267753011681	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1267753011682	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1267753011683	metal binding site [ion binding]; metal-binding site
1267753011684	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
1267753011685	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
1267753011686	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1267753011687	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1267753011688	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753011689	Walker A motif; other site
1267753011690	ATP binding site [chemical binding]; other site
1267753011691	Walker B motif; other site
1267753011692	arginine finger; other site
1267753011693	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1267753011694	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1267753011695	dimerization interface [polypeptide binding]; other site
1267753011696	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1267753011697	ATP binding site [chemical binding]; other site
1267753011698	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1267753011699	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1267753011700	hydrogenase assembly chaperone; Provisional; Region: PRK10409
1267753011701	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
1267753011702	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
1267753011703	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
1267753011704	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
1267753011705	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
1267753011706	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
1267753011707	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1267753011708	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1267753011709	NADH dehydrogenase; Region: NADHdh; cl00469
1267753011710	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
1267753011711	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
1267753011712	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
1267753011713	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
1267753011714	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1267753011715	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
1267753011716	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
1267753011717	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
1267753011718	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
1267753011719	nickel binding site [ion binding]; other site
1267753011720	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
1267753011721	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1267753011722	Acylphosphatase; Region: Acylphosphatase; pfam00708
1267753011723	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1267753011724	HypF finger; Region: zf-HYPF; pfam07503
1267753011725	HypF finger; Region: zf-HYPF; pfam07503
1267753011726	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1267753011727	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
1267753011728	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1267753011729	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753011730	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
1267753011731	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1267753011732	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1267753011733	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
1267753011734	iron binding site [ion binding]; other site
1267753011735	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
1267753011736	GAF domain; Region: GAF; pfam01590
1267753011737	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753011738	Walker A motif; other site
1267753011739	ATP binding site [chemical binding]; other site
1267753011740	Walker B motif; other site
1267753011741	arginine finger; other site
1267753011742	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
1267753011743	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1267753011744	putative active site [active]
1267753011745	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1267753011746	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
1267753011747	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
1267753011748	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1267753011749	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
1267753011750	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
1267753011751	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
1267753011752	putative NAD(P) binding site [chemical binding]; other site
1267753011753	active site
1267753011754	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
1267753011755	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
1267753011756	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
1267753011757	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
1267753011758	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
1267753011759	Transglycosylase SLT domain; Region: SLT_2; pfam13406
1267753011760	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1267753011761	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1267753011762	hypothetical protein; Validated; Region: PRK03661
1267753011763	recombinase A; Provisional; Region: recA; PRK09354
1267753011764	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1267753011765	hexamer interface [polypeptide binding]; other site
1267753011766	Walker A motif; other site
1267753011767	ATP binding site [chemical binding]; other site
1267753011768	Walker B motif; other site
1267753011769	recombination regulator RecX; Reviewed; Region: recX; PRK00117
1267753011770	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1267753011771	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1267753011772	motif 1; other site
1267753011773	active site
1267753011774	motif 2; other site
1267753011775	motif 3; other site
1267753011776	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1267753011777	DHHA1 domain; Region: DHHA1; pfam02272
1267753011778	carbon storage regulator; Provisional; Region: PRK01712
1267753011779	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
1267753011780	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753011781	motif II; other site
1267753011782	Predicted membrane protein [Function unknown]; Region: COG1238
1267753011783	glutamate--cysteine ligase; Provisional; Region: PRK02107
1267753011784	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1267753011785	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
1267753011786	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1267753011787	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011788	putative substrate translocation pore; other site
1267753011789	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011790	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
1267753011791	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1267753011792	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753011793	transcriptional repressor MprA; Provisional; Region: PRK10870
1267753011794	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1267753011795	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1267753011796	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753011797	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
1267753011798	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1267753011799	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
1267753011800	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753011801	dimer interface [polypeptide binding]; other site
1267753011802	conserved gate region; other site
1267753011803	putative PBP binding loops; other site
1267753011804	ABC-ATPase subunit interface; other site
1267753011805	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
1267753011806	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1267753011807	Walker A/P-loop; other site
1267753011808	ATP binding site [chemical binding]; other site
1267753011809	Q-loop/lid; other site
1267753011810	ABC transporter signature motif; other site
1267753011811	Walker B; other site
1267753011812	D-loop; other site
1267753011813	H-loop/switch region; other site
1267753011814	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1267753011815	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
1267753011816	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1267753011817	dimer interface [polypeptide binding]; other site
1267753011818	putative radical transfer pathway; other site
1267753011819	diiron center [ion binding]; other site
1267753011820	tyrosyl radical; other site
1267753011821	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
1267753011822	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
1267753011823	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1267753011824	active site
1267753011825	dimer interface [polypeptide binding]; other site
1267753011826	catalytic residues [active]
1267753011827	effector binding site; other site
1267753011828	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1267753011829	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
1267753011830	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1267753011831	catalytic residues [active]
1267753011832	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
1267753011833	Uncharacterized conserved protein [Function unknown]; Region: COG2128
1267753011834	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1267753011835	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753011836	DNA-binding site [nucleotide binding]; DNA binding site
1267753011837	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753011838	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753011839	homodimer interface [polypeptide binding]; other site
1267753011840	catalytic residue [active]
1267753011841	hypothetical protein; Provisional; Region: PRK10132
1267753011842	hypothetical protein; Provisional; Region: PRK10556
1267753011843	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
1267753011844	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
1267753011845	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
1267753011846	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1267753011847	active site residue [active]
1267753011848	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
1267753011849	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1267753011850	dimerization interface [polypeptide binding]; other site
1267753011851	putative DNA binding site [nucleotide binding]; other site
1267753011852	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1267753011853	putative Zn2+ binding site [ion binding]; other site
1267753011854	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
1267753011855	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1267753011856	bacterial OsmY and nodulation domain; Region: BON; smart00749
1267753011857	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1267753011858	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
1267753011859	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753011860	DNA-binding site [nucleotide binding]; DNA binding site
1267753011861	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
1267753011862	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
1267753011863	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
1267753011864	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1267753011865	inhibitor-cofactor binding pocket; inhibition site
1267753011866	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753011867	catalytic residue [active]
1267753011868	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
1267753011869	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1267753011870	tetramerization interface [polypeptide binding]; other site
1267753011871	NAD(P) binding site [chemical binding]; other site
1267753011872	catalytic residues [active]
1267753011873	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1267753011874	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1267753011875	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
1267753011876	substrate binding pocket [chemical binding]; other site
1267753011877	active site
1267753011878	iron coordination sites [ion binding]; other site
1267753011879	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
1267753011880	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
1267753011881	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
1267753011882	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
1267753011883	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753011884	active site
1267753011885	phosphorylation site [posttranslational modification]
1267753011886	intermolecular recognition site; other site
1267753011887	dimerization interface [polypeptide binding]; other site
1267753011888	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753011889	DNA binding site [nucleotide binding]
1267753011890	potential frameshift: common BLAST hit: gi|194737888|ref|YP_002115738.1| tricarboxylic transport: regulatory protein
1267753011891	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
1267753011892	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
1267753011893	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1267753011894	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
1267753011895	secreted effector protein PipB2; Provisional; Region: PRK15196
1267753011896	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1267753011897	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1267753011898	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1267753011899	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1267753011900	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1267753011901	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1267753011902	potential frameshift: common BLAST hit: gi|383497458|ref|YP_005398147.1| TonB-dependent outer membrane siderophore receptor protein
1267753011903	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1267753011904	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
1267753011905	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
1267753011906	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1267753011907	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1267753011908	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1267753011909	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753011910	Walker A/P-loop; other site
1267753011911	ATP binding site [chemical binding]; other site
1267753011912	Q-loop/lid; other site
1267753011913	ABC transporter signature motif; other site
1267753011914	Walker B; other site
1267753011915	D-loop; other site
1267753011916	H-loop/switch region; other site
1267753011917	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1267753011918	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1267753011919	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753011920	Walker A/P-loop; other site
1267753011921	ATP binding site [chemical binding]; other site
1267753011922	Q-loop/lid; other site
1267753011923	ABC transporter signature motif; other site
1267753011924	Walker B; other site
1267753011925	D-loop; other site
1267753011926	H-loop/switch region; other site
1267753011927	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
1267753011928	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
1267753011929	homodimer interface [polypeptide binding]; other site
1267753011930	active site
1267753011931	TDP-binding site; other site
1267753011932	acceptor substrate-binding pocket; other site
1267753011933	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1267753011934	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1267753011935	catalytic residues [active]
1267753011936	catalytic nucleophile [active]
1267753011937	Presynaptic Site I dimer interface [polypeptide binding]; other site
1267753011938	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1267753011939	Synaptic Flat tetramer interface [polypeptide binding]; other site
1267753011940	Synaptic Site I dimer interface [polypeptide binding]; other site
1267753011941	DNA binding site [nucleotide binding]
1267753011942	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1267753011943	DNA-binding interface [nucleotide binding]; DNA binding site
1267753011944	flagellin; Validated; Region: PRK08026
1267753011945	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1267753011946	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
1267753011947	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1267753011948	Repressor of phase-1 flagellin; Region: Flag1_repress; pfam03614
1267753011949	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
1267753011950	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
1267753011951	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
1267753011952	active site
1267753011953	metal binding site [ion binding]; metal-binding site
1267753011954	D5 N terminal like; Region: D5_N; smart00885
1267753011955	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
1267753011956	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
1267753011957	Ash protein family; Region: Phage_ASH; pfam10554
1267753011958	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
1267753011959	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1267753011960	Phage polarity suppression protein (Psu); Region: Psu; pfam07455
1267753011961	Domain of unknown function DUF87; Region: DUF87; pfam01935
1267753011962	HerA helicase [Replication, recombination, and repair]; Region: COG0433
1267753011963	integrase; Provisional; Region: PRK09692
1267753011964	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1267753011965	active site
1267753011966	Int/Topo IB signature motif; other site
1267753011967	GrpE; Region: GrpE; pfam01025
1267753011968	integrase; Provisional; Region: int; PHA02601
1267753011969	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
1267753011970	dimer interface [polypeptide binding]; other site
1267753011971	active site
1267753011972	catalytic residues [active]
1267753011973	Int/Topo IB signature motif; other site
1267753011974	Predicted transcriptional regulator [Transcription]; Region: COG2932
1267753011975	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1267753011976	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
1267753011977	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
1267753011978	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
1267753011979	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1267753011980	DksA-like zinc finger domain containing protein; Region: PHA00080
1267753011981	DNA adenine methylase (dam); Region: dam; TIGR00571
1267753011982	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1267753011983	DinI-like family; Region: DinI; pfam06183
1267753011984	portal vertex protein; Provisional; Region: Q; PHA02536
1267753011985	Phage portal protein; Region: Phage_portal; pfam04860
1267753011986	terminase ATPase subunit; Provisional; Region: P; PHA02535
1267753011987	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1267753011988	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
1267753011989	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1267753011990	capsid protein; Provisional; Region: N; PHA02538
1267753011991	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1267753011992	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1267753011993	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1267753011994	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
1267753011995	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
1267753011996	catalytic residues [active]
1267753011997	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1267753011998	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1267753011999	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1267753012000	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1267753012001	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1267753012002	baseplate wedge subunit; Provisional; Region: W; PHA02516
1267753012003	baseplate assembly protein; Provisional; Region: J; PHA02568
1267753012004	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
1267753012005	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
1267753012006	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1267753012007	Phage Tail Collar Domain; Region: Collar; pfam07484
1267753012008	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1267753012009	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1267753012010	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
1267753012011	DNA-binding interface [nucleotide binding]; DNA binding site
1267753012012	major tail sheath protein; Provisional; Region: FI; PHA02560
1267753012013	major tail tube protein; Provisional; Region: FII; PHA02600
1267753012014	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1267753012015	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1267753012016	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1267753012017	Phage protein U [General function prediction only]; Region: COG3499
1267753012018	tail protein; Provisional; Region: D; PHA02561
1267753012019	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1267753012020	ORF6N domain; Region: ORF6N; pfam10543
1267753012021	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
1267753012022	HlyD family secretion protein; Region: HlyD_3; pfam13437
1267753012023	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
1267753012024	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1267753012025	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753012026	Walker A/P-loop; other site
1267753012027	ATP binding site [chemical binding]; other site
1267753012028	Q-loop/lid; other site
1267753012029	ABC transporter signature motif; other site
1267753012030	Walker B; other site
1267753012031	D-loop; other site
1267753012032	H-loop/switch region; other site
1267753012033	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1267753012034	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012035	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012036	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012037	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012038	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012039	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012040	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012041	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012042	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012043	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1267753012044	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012045	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012046	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
1267753012047	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012048	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
1267753012049	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
1267753012050	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1267753012051	SmpB-tmRNA interface; other site
1267753012052	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
1267753012053	putative coenzyme Q binding site [chemical binding]; other site
1267753012054	hypothetical protein; Validated; Region: PRK01777
1267753012055	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
1267753012056	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
1267753012057	recombination and repair protein; Provisional; Region: PRK10869
1267753012058	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1267753012059	Walker A/P-loop; other site
1267753012060	ATP binding site [chemical binding]; other site
1267753012061	Q-loop/lid; other site
1267753012062	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1267753012063	ABC transporter signature motif; other site
1267753012064	Walker B; other site
1267753012065	D-loop; other site
1267753012066	H-loop/switch region; other site
1267753012067	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
1267753012068	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
1267753012069	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1267753012070	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1267753012071	dimer interface [polypeptide binding]; other site
1267753012072	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1267753012073	hypothetical protein; Provisional; Region: PRK11573
1267753012074	Domain of unknown function DUF21; Region: DUF21; pfam01595
1267753012075	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1267753012076	Transporter associated domain; Region: CorC_HlyC; smart01091
1267753012077	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
1267753012078	signal recognition particle protein; Provisional; Region: PRK10867
1267753012079	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1267753012080	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1267753012081	P loop; other site
1267753012082	GTP binding site [chemical binding]; other site
1267753012083	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1267753012084	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1267753012085	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1267753012086	RimM N-terminal domain; Region: RimM; pfam01782
1267753012087	PRC-barrel domain; Region: PRC; pfam05239
1267753012088	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1267753012089	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1267753012090	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
1267753012091	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
1267753012092	tail protein; Provisional; Region: D; PHA02561
1267753012093	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
1267753012094	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
1267753012095	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
1267753012096	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
1267753012097	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
1267753012098	major tail tube protein; Provisional; Region: FII; PHA02600
1267753012099	major tail sheath protein; Provisional; Region: FI; PHA02560
1267753012100	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1267753012101	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
1267753012102	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1267753012103	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1267753012104	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
1267753012105	phage tail protein, P2 protein I family; Region: tail_P2_I; TIGR01634
1267753012106	baseplate assembly protein; Provisional; Region: J; PHA02568
1267753012107	baseplate wedge subunit; Provisional; Region: W; PHA02516
1267753012108	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
1267753012109	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
1267753012110	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
1267753012111	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
1267753012112	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
1267753012113	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
1267753012114	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1267753012115	catalytic residue [active]
1267753012116	Phage holin family 2; Region: Phage_holin_2; pfam04550
1267753012117	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
1267753012118	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
1267753012119	terminase endonuclease subunit; Provisional; Region: M; PHA02537
1267753012120	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
1267753012121	Phage major capsid protein, P2 family; Region: Phage_cap_P2; pfam05125
1267753012122	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
1267753012123	terminase ATPase subunit; Provisional; Region: P; PHA02535
1267753012124	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
1267753012125	terminase ATPase subunit; Provisional; Region: P; PHA02535
1267753012126	portal vertex protein; Provisional; Region: Q; PHA02536
1267753012127	Phage portal protein; Region: Phage_portal; pfam04860
1267753012128	DinI-like family; Region: DinI; pfam06183
1267753012129	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
1267753012130	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
1267753012131	Domain of Unknown Function with PDB structure (DUF3850); Region: DUF3850; pfam12961
1267753012132	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1267753012133	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1267753012134	active site
1267753012135	catalytic site [active]
1267753012136	substrate binding site [chemical binding]; other site
1267753012137	DksA-like zinc finger domain containing protein; Region: PHA00080
1267753012138	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
1267753012139	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
1267753012140	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
1267753012141	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1267753012142	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
1267753012143	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
1267753012144	integrase; Provisional; Region: int; PHA02601
1267753012145	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753012146	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1267753012147	active site
1267753012148	DNA binding site [nucleotide binding]
1267753012149	Int/Topo IB signature motif; other site
1267753012150	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
1267753012151	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1267753012152	metal binding site [ion binding]; metal-binding site
1267753012153	active site
1267753012154	I-site; other site
1267753012155	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
1267753012156	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
1267753012157	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1267753012158	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
1267753012159	Chorismate mutase type II; Region: CM_2; cl00693
1267753012160	prephenate dehydrogenase; Validated; Region: PRK08507
1267753012161	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1267753012162	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
1267753012163	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
1267753012164	Prephenate dehydratase; Region: PDT; pfam00800
1267753012165	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1267753012166	putative L-Phe binding site [chemical binding]; other site
1267753012167	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1267753012168	30S subunit binding site; other site
1267753012169	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
1267753012170	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
1267753012171	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
1267753012172	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1267753012173	RNA binding surface [nucleotide binding]; other site
1267753012174	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1267753012175	active site
1267753012176	hypothetical protein; Provisional; Region: PRK10723
1267753012177	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1267753012178	protein disaggregation chaperone; Provisional; Region: PRK10865
1267753012179	Clp amino terminal domain; Region: Clp_N; pfam02861
1267753012180	Clp amino terminal domain; Region: Clp_N; pfam02861
1267753012181	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753012182	Walker A motif; other site
1267753012183	ATP binding site [chemical binding]; other site
1267753012184	Walker B motif; other site
1267753012185	arginine finger; other site
1267753012186	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753012187	Walker A motif; other site
1267753012188	ATP binding site [chemical binding]; other site
1267753012189	Walker B motif; other site
1267753012190	arginine finger; other site
1267753012191	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1267753012192	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1267753012193	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1267753012194	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753012195	putative substrate translocation pore; other site
1267753012196	lipoprotein; Provisional; Region: PRK10759
1267753012197	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
1267753012198	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
1267753012199	domain interface [polypeptide binding]; other site
1267753012200	putative active site [active]
1267753012201	catalytic site [active]
1267753012202	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
1267753012203	domain interface [polypeptide binding]; other site
1267753012204	putative active site [active]
1267753012205	catalytic site [active]
1267753012206	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
1267753012207	CoA binding domain; Region: CoA_binding_2; pfam13380
1267753012208	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
1267753012209	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
1267753012210	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1267753012211	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753012212	Coenzyme A binding pocket [chemical binding]; other site
1267753012213	Uncharacterized conserved protein [Function unknown]; Region: COG3148
1267753012214	thioredoxin 2; Provisional; Region: PRK10996
1267753012215	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
1267753012216	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1267753012217	catalytic residues [active]
1267753012218	putative methyltransferase; Provisional; Region: PRK10864
1267753012219	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1267753012220	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1267753012221	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1267753012222	ligand binding site [chemical binding]; other site
1267753012223	active site
1267753012224	UGI interface [polypeptide binding]; other site
1267753012225	catalytic site [active]
1267753012226	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
1267753012227	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
1267753012228	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753012229	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753012230	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1267753012231	dimerization interface [polypeptide binding]; other site
1267753012232	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1267753012233	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1267753012234	ATP binding site [chemical binding]; other site
1267753012235	Mg++ binding site [ion binding]; other site
1267753012236	motif III; other site
1267753012237	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1267753012238	nucleotide binding region [chemical binding]; other site
1267753012239	ATP-binding site [chemical binding]; other site
1267753012240	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1267753012241	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753012242	S-adenosylmethionine binding site [chemical binding]; other site
1267753012243	L-aspartate oxidase; Provisional; Region: PRK09077
1267753012244	L-aspartate oxidase; Provisional; Region: PRK06175
1267753012245	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1267753012246	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
1267753012247	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1267753012248	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1267753012249	DNA binding residues [nucleotide binding]
1267753012250	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
1267753012251	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
1267753012252	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
1267753012253	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
1267753012254	anti-sigma E factor; Provisional; Region: rseB; PRK09455
1267753012255	SoxR reducing system protein RseC; Provisional; Region: PRK10862
1267753012256	integrase; Provisional; Region: PRK09692
1267753012257	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
1267753012258	active site
1267753012259	Int/Topo IB signature motif; other site
1267753012260	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
1267753012261	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1267753012262	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
1267753012263	phage recombination protein Bet; Region: bet_lambda; TIGR01913
1267753012264	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
1267753012265	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
1267753012266	Uncharacterized conserved protein [Function unknown]; Region: COG4933
1267753012267	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753012268	transcriptional repressor DicA; Reviewed; Region: PRK09706
1267753012269	non-specific DNA binding site [nucleotide binding]; other site
1267753012270	salt bridge; other site
1267753012271	sequence-specific DNA binding site [nucleotide binding]; other site
1267753012272	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
1267753012273	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
1267753012274	Replication protein P; Region: Phage_lambda_P; pfam06992
1267753012275	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1267753012276	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
1267753012277	NFkB-p65-degrading zinc protease; Region: Peptidase_M85; pfam13678
1267753012278	DinI-like family; Region: DinI; pfam06183
1267753012279	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
1267753012280	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
1267753012281	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
1267753012282	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
1267753012283	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
1267753012284	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
1267753012285	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
1267753012286	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
1267753012287	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1267753012288	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
1267753012289	oligomer interface [polypeptide binding]; other site
1267753012290	active site residues [active]
1267753012291	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
1267753012292	Uncharacterized conserved protein (DUF2190); Region: DUF2190; cl02289
1267753012293	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
1267753012294	GTP-binding protein LepA; Provisional; Region: PRK05433
1267753012295	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1267753012296	G1 box; other site
1267753012297	putative GEF interaction site [polypeptide binding]; other site
1267753012298	GTP/Mg2+ binding site [chemical binding]; other site
1267753012299	Switch I region; other site
1267753012300	G2 box; other site
1267753012301	G3 box; other site
1267753012302	Switch II region; other site
1267753012303	G4 box; other site
1267753012304	G5 box; other site
1267753012305	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1267753012306	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1267753012307	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1267753012308	signal peptidase I; Provisional; Region: PRK10861
1267753012309	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1267753012310	Catalytic site [active]
1267753012311	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1267753012312	ribonuclease III; Reviewed; Region: rnc; PRK00102
1267753012313	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1267753012314	dimerization interface [polypeptide binding]; other site
1267753012315	active site
1267753012316	metal binding site [ion binding]; metal-binding site
1267753012317	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1267753012318	dsRNA binding site [nucleotide binding]; other site
1267753012319	GTPase Era; Reviewed; Region: era; PRK00089
1267753012320	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1267753012321	G1 box; other site
1267753012322	GTP/Mg2+ binding site [chemical binding]; other site
1267753012323	Switch I region; other site
1267753012324	G2 box; other site
1267753012325	Switch II region; other site
1267753012326	G3 box; other site
1267753012327	G4 box; other site
1267753012328	G5 box; other site
1267753012329	KH domain; Region: KH_2; pfam07650
1267753012330	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1267753012331	Recombination protein O N terminal; Region: RecO_N; pfam11967
1267753012332	Recombination protein O C terminal; Region: RecO_C; pfam02565
1267753012333	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1267753012334	active site
1267753012335	hydrophilic channel; other site
1267753012336	dimerization interface [polypeptide binding]; other site
1267753012337	catalytic residues [active]
1267753012338	active site lid [active]
1267753012339	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1267753012340	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1267753012341	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753012342	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753012343	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1267753012344	dimerization interface [polypeptide binding]; other site
1267753012345	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1267753012346	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753012347	putative substrate translocation pore; other site
1267753012348	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1267753012349	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1267753012350	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1267753012351	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1267753012352	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
1267753012353	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1267753012354	putative active site [active]
1267753012355	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1267753012356	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1267753012357	putative active site [active]
1267753012358	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
1267753012359	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1267753012360	active site turn [active]
1267753012361	phosphorylation site [posttranslational modification]
1267753012362	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1267753012363	hypothetical protein; Provisional; Region: PRK11590
1267753012364	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1267753012365	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1267753012366	nucleoside/Zn binding site; other site
1267753012367	dimer interface [polypeptide binding]; other site
1267753012368	catalytic motif [active]
1267753012369	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
1267753012370	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753012371	substrate binding pocket [chemical binding]; other site
1267753012372	membrane-bound complex binding site; other site
1267753012373	hinge residues; other site
1267753012374	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1267753012375	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1267753012376	catalytic residue [active]
1267753012377	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1267753012378	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1267753012379	dimerization interface [polypeptide binding]; other site
1267753012380	ATP binding site [chemical binding]; other site
1267753012381	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
1267753012382	dimerization interface [polypeptide binding]; other site
1267753012383	ATP binding site [chemical binding]; other site
1267753012384	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1267753012385	putative active site [active]
1267753012386	catalytic triad [active]
1267753012387	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1267753012388	HAMP domain; Region: HAMP; pfam00672
1267753012389	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753012390	dimer interface [polypeptide binding]; other site
1267753012391	phosphorylation site [posttranslational modification]
1267753012392	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753012393	ATP binding site [chemical binding]; other site
1267753012394	Mg2+ binding site [ion binding]; other site
1267753012395	G-X-G motif; other site
1267753012396	hypothetical protein; Provisional; Region: PRK10722
1267753012397	response regulator GlrR; Provisional; Region: PRK15115
1267753012398	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753012399	active site
1267753012400	phosphorylation site [posttranslational modification]
1267753012401	intermolecular recognition site; other site
1267753012402	dimerization interface [polypeptide binding]; other site
1267753012403	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753012404	Walker A motif; other site
1267753012405	ATP binding site [chemical binding]; other site
1267753012406	Walker B motif; other site
1267753012407	arginine finger; other site
1267753012408	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
1267753012409	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1267753012410	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1267753012411	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753012412	putative substrate translocation pore; other site
1267753012413	POT family; Region: PTR2; pfam00854
1267753012414	lysine decarboxylase CadA; Provisional; Region: PRK15400
1267753012415	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
1267753012416	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1267753012417	homodimer interface [polypeptide binding]; other site
1267753012418	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753012419	catalytic residue [active]
1267753012420	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1267753012421	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
1267753012422	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
1267753012423	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1267753012424	DNA binding site [nucleotide binding]
1267753012425	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1267753012426	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1267753012427	heme-binding site [chemical binding]; other site
1267753012428	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1267753012429	FAD binding pocket [chemical binding]; other site
1267753012430	FAD binding motif [chemical binding]; other site
1267753012431	phosphate binding motif [ion binding]; other site
1267753012432	beta-alpha-beta structure motif; other site
1267753012433	NAD binding pocket [chemical binding]; other site
1267753012434	Heme binding  pocket [chemical binding]; other site
1267753012435	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1267753012436	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1267753012437	dimer interface [polypeptide binding]; other site
1267753012438	active site
1267753012439	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1267753012440	folate binding site [chemical binding]; other site
1267753012441	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
1267753012442	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753012443	putative substrate translocation pore; other site
1267753012444	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
1267753012445	PRD domain; Region: PRD; pfam00874
1267753012446	PRD domain; Region: PRD; pfam00874
1267753012447	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
1267753012448	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
1267753012449	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
1267753012450	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1267753012451	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1267753012452	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
1267753012453	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
1267753012454	FAD binding pocket [chemical binding]; other site
1267753012455	FAD binding motif [chemical binding]; other site
1267753012456	phosphate binding motif [ion binding]; other site
1267753012457	beta-alpha-beta structure motif; other site
1267753012458	NAD binding pocket [chemical binding]; other site
1267753012459	Iron coordination center [ion binding]; other site
1267753012460	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
1267753012461	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1267753012462	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1267753012463	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1267753012464	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1267753012465	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
1267753012466	active site
1267753012467	dimerization interface [polypeptide binding]; other site
1267753012468	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
1267753012469	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
1267753012470	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
1267753012471	Rrf2 family protein; Region: rrf2_super; TIGR00738
1267753012472	potential frameshift: common BLAST hit: gi|409251213|ref|YP_006887015.1| cysteine desulfurase
1267753012473	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1267753012474	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1267753012475	trimerization site [polypeptide binding]; other site
1267753012476	active site
1267753012477	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
1267753012478	co-chaperone HscB; Provisional; Region: hscB; PRK05014
1267753012479	DnaJ domain; Region: DnaJ; pfam00226
1267753012480	HSP70 interaction site [polypeptide binding]; other site
1267753012481	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
1267753012482	chaperone protein HscA; Provisional; Region: hscA; PRK05183
1267753012483	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
1267753012484	nucleotide binding site [chemical binding]; other site
1267753012485	putative NEF/HSP70 interaction site [polypeptide binding]; other site
1267753012486	SBD interface [polypeptide binding]; other site
1267753012487	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1267753012488	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1267753012489	catalytic loop [active]
1267753012490	iron binding site [ion binding]; other site
1267753012491	hypothetical protein; Provisional; Region: PRK10721
1267753012492	aminopeptidase B; Provisional; Region: PRK05015
1267753012493	Peptidase; Region: DUF3663; pfam12404
1267753012494	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1267753012495	interface (dimer of trimers) [polypeptide binding]; other site
1267753012496	Substrate-binding/catalytic site; other site
1267753012497	Zn-binding sites [ion binding]; other site
1267753012498	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
1267753012499	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
1267753012500	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1267753012501	active site residue [active]
1267753012502	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1267753012503	active site residue [active]
1267753012504	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1267753012505	MG2 domain; Region: A2M_N; pfam01835
1267753012506	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1267753012507	surface patch; other site
1267753012508	thioester region; other site
1267753012509	specificity defining residues; other site
1267753012510	penicillin-binding protein 1C; Provisional; Region: PRK11240
1267753012511	Transglycosylase; Region: Transgly; pfam00912
1267753012512	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1267753012513	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1267753012514	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
1267753012515	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
1267753012516	putative [Fe4-S4] binding site [ion binding]; other site
1267753012517	putative molybdopterin cofactor binding site [chemical binding]; other site
1267753012518	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
1267753012519	putative molybdopterin cofactor binding site; other site
1267753012520	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
1267753012521	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753012522	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
1267753012523	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753012524	hydrogenase 4 subunit H; Validated; Region: PRK08222
1267753012525	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1267753012526	active site
1267753012527	multimer interface [polypeptide binding]; other site
1267753012528	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
1267753012529	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1267753012530	FeS/SAM binding site; other site
1267753012531	cytoskeletal protein RodZ; Provisional; Region: PRK10856
1267753012532	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1267753012533	non-specific DNA binding site [nucleotide binding]; other site
1267753012534	salt bridge; other site
1267753012535	sequence-specific DNA binding site [nucleotide binding]; other site
1267753012536	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
1267753012537	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1267753012538	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1267753012539	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1267753012540	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1267753012541	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1267753012542	dimer interface [polypeptide binding]; other site
1267753012543	motif 1; other site
1267753012544	active site
1267753012545	motif 2; other site
1267753012546	motif 3; other site
1267753012547	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1267753012548	anticodon binding site; other site
1267753012549	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
1267753012550	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
1267753012551	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
1267753012552	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
1267753012553	Trp docking motif [polypeptide binding]; other site
1267753012554	active site
1267753012555	GTP-binding protein Der; Reviewed; Region: PRK00093
1267753012556	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1267753012557	G1 box; other site
1267753012558	GTP/Mg2+ binding site [chemical binding]; other site
1267753012559	Switch I region; other site
1267753012560	G2 box; other site
1267753012561	Switch II region; other site
1267753012562	G3 box; other site
1267753012563	G4 box; other site
1267753012564	G5 box; other site
1267753012565	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1267753012566	G1 box; other site
1267753012567	GTP/Mg2+ binding site [chemical binding]; other site
1267753012568	Switch I region; other site
1267753012569	G2 box; other site
1267753012570	G3 box; other site
1267753012571	Switch II region; other site
1267753012572	G4 box; other site
1267753012573	G5 box; other site
1267753012574	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
1267753012575	intimin-like protein SinH; Provisional; Region: PRK15318
1267753012576	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1267753012577	intimin-like protein SinH; Provisional; Region: PRK15318
1267753012578	outer membrane protein RatA; Provisional; Region: PRK15315
1267753012579	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012580	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012581	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012582	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012583	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012584	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012585	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012586	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012587	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012588	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012589	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012590	outer membrane protein RatB; Provisional; Region: PRK15314
1267753012591	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012592	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012593	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012594	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012595	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012596	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012597	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012598	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012599	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012600	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012601	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012602	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012603	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012604	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012605	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
1267753012606	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
1267753012607	AIDA autotransporter-like protein ShdA; Provisional; Region: PRK15319
1267753012608	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
1267753012609	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1267753012610	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1267753012611	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1267753012612	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
1267753012613	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
1267753012614	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
1267753012615	Autotransporter beta-domain; Region: Autotransporter; smart00869
1267753012616	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1267753012617	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1267753012618	generic binding surface II; other site
1267753012619	generic binding surface I; other site
1267753012620	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1267753012621	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1267753012622	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1267753012623	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1267753012624	active site
1267753012625	GMP synthase; Reviewed; Region: guaA; PRK00074
1267753012626	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1267753012627	AMP/PPi binding site [chemical binding]; other site
1267753012628	candidate oxyanion hole; other site
1267753012629	catalytic triad [active]
1267753012630	potential glutamine specificity residues [chemical binding]; other site
1267753012631	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1267753012632	ATP Binding subdomain [chemical binding]; other site
1267753012633	Ligand Binding sites [chemical binding]; other site
1267753012634	Dimerization subdomain; other site
1267753012635	Uncharacterized protein conserved in bacteria (DUF2251); Region: DUF2251; pfam10008
1267753012636	potential frameshift: common BLAST hit: gi|378769432|ref|YP_005197907.1| site-specific recombinase, phage integrase family
1267753012637	Uncharacterized conserved protein [Function unknown]; Region: COG5361
1267753012638	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
1267753012639	Protein of unknown function (DUF1214); Region: DUF1214; cl08447
1267753012640	Uncharacterized conserved protein [Function unknown]; Region: COG5361
1267753012641	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
1267753012642	Protein of unknown function (DUF1214); Region: DUF1214; cl08447
1267753012643	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
1267753012644	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
1267753012645	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1267753012646	MASE1; Region: MASE1; pfam05231
1267753012647	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1267753012648	diguanylate cyclase; Region: GGDEF; smart00267
1267753012649	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753012650	exopolyphosphatase; Provisional; Region: PRK10854
1267753012651	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1267753012652	nucleotide binding site [chemical binding]; other site
1267753012653	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1267753012654	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1267753012655	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1267753012656	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1267753012657	putative active site [active]
1267753012658	catalytic site [active]
1267753012659	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1267753012660	domain interface [polypeptide binding]; other site
1267753012661	active site
1267753012662	catalytic site [active]
1267753012663	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1267753012664	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1267753012665	active site
1267753012666	substrate binding site [chemical binding]; other site
1267753012667	cosubstrate binding site; other site
1267753012668	catalytic site [active]
1267753012669	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1267753012670	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1267753012671	dimerization interface [polypeptide binding]; other site
1267753012672	putative ATP binding site [chemical binding]; other site
1267753012673	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1267753012674	active site
1267753012675	uracil transporter; Provisional; Region: PRK10720
1267753012676	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
1267753012677	DNA replication initiation factor; Provisional; Region: PRK08084
1267753012678	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1267753012679	ArsC family; Region: ArsC; pfam03960
1267753012680	catalytic residues [active]
1267753012681	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
1267753012682	Peptidase family M48; Region: Peptidase_M48; cl12018
1267753012683	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1267753012684	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1267753012685	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
1267753012686	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
1267753012687	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1267753012688	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
1267753012689	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1267753012690	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1267753012691	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1267753012692	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1267753012693	catalytic triad [active]
1267753012694	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
1267753012695	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
1267753012696	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1267753012697	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1267753012698	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1267753012699	dimer interface [polypeptide binding]; other site
1267753012700	active site
1267753012701	catalytic residue [active]
1267753012702	lipoprotein; Provisional; Region: PRK11679
1267753012703	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
1267753012704	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1267753012705	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1267753012706	ATP binding site [chemical binding]; other site
1267753012707	active site
1267753012708	substrate binding site [chemical binding]; other site
1267753012709	Predicted metalloprotease [General function prediction only]; Region: COG2321
1267753012710	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1267753012711	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
1267753012712	Helicase; Region: Helicase_RecD; pfam05127
1267753012713	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1267753012714	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1267753012715	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
1267753012716	hypothetical protein; Provisional; Region: PRK13664
1267753012717	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
1267753012718	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1267753012719	metal binding site [ion binding]; metal-binding site
1267753012720	dimer interface [polypeptide binding]; other site
1267753012721	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
1267753012722	ArsC family; Region: ArsC; pfam03960
1267753012723	putative catalytic residues [active]
1267753012724	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
1267753012725	Protein export membrane protein; Region: SecD_SecF; cl14618
1267753012726	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
1267753012727	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1267753012728	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1267753012729	dimerization interface [polypeptide binding]; other site
1267753012730	Histidine kinase; Region: HisKA_3; pfam07730
1267753012731	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753012732	ATP binding site [chemical binding]; other site
1267753012733	Mg2+ binding site [ion binding]; other site
1267753012734	G-X-G motif; other site
1267753012735	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
1267753012736	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753012737	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1267753012738	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1267753012739	putative periplasmic esterase; Provisional; Region: PRK03642
1267753012740	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1267753012741	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
1267753012742	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1267753012743	dimer interface [polypeptide binding]; other site
1267753012744	ADP-ribose binding site [chemical binding]; other site
1267753012745	active site
1267753012746	nudix motif; other site
1267753012747	metal binding site [ion binding]; metal-binding site
1267753012748	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
1267753012749	transketolase; Reviewed; Region: PRK12753
1267753012750	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1267753012751	TPP-binding site [chemical binding]; other site
1267753012752	dimer interface [polypeptide binding]; other site
1267753012753	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1267753012754	PYR/PP interface [polypeptide binding]; other site
1267753012755	dimer interface [polypeptide binding]; other site
1267753012756	TPP binding site [chemical binding]; other site
1267753012757	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1267753012758	transaldolase-like protein; Provisional; Region: PTZ00411
1267753012759	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
1267753012760	active site
1267753012761	dimer interface [polypeptide binding]; other site
1267753012762	catalytic residue [active]
1267753012763	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1267753012764	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1267753012765	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1267753012766	putative NAD(P) binding site [chemical binding]; other site
1267753012767	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1267753012768	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
1267753012769	putative hexamer interface [polypeptide binding]; other site
1267753012770	putative hexagonal pore; other site
1267753012771	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1267753012772	G1 box; other site
1267753012773	GTP/Mg2+ binding site [chemical binding]; other site
1267753012774	G2 box; other site
1267753012775	Switch I region; other site
1267753012776	G3 box; other site
1267753012777	Switch II region; other site
1267753012778	G4 box; other site
1267753012779	G5 box; other site
1267753012780	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
1267753012781	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
1267753012782	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
1267753012783	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1267753012784	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1267753012785	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1267753012786	Hexamer interface [polypeptide binding]; other site
1267753012787	Putative hexagonal pore residue; other site
1267753012788	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1267753012789	Hexamer/Pentamer interface [polypeptide binding]; other site
1267753012790	central pore; other site
1267753012791	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
1267753012792	putative catalytic cysteine [active]
1267753012793	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
1267753012794	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1267753012795	nucleotide binding site [chemical binding]; other site
1267753012796	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
1267753012797	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
1267753012798	active site
1267753012799	metal binding site [ion binding]; metal-binding site
1267753012800	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
1267753012801	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
1267753012802	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
1267753012803	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
1267753012804	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
1267753012805	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
1267753012806	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
1267753012807	putative hexamer interface [polypeptide binding]; other site
1267753012808	putative hexagonal pore; other site
1267753012809	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
1267753012810	putative hexamer interface [polypeptide binding]; other site
1267753012811	putative hexagonal pore; other site
1267753012812	carboxysome structural protein EutK; Provisional; Region: PRK15466
1267753012813	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1267753012814	Hexamer interface [polypeptide binding]; other site
1267753012815	Hexagonal pore residue; other site
1267753012816	transcriptional regulator EutR; Provisional; Region: PRK10130
1267753012817	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753012818	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753012819	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1267753012820	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1267753012821	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
1267753012822	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1267753012823	active site
1267753012824	metal binding site [ion binding]; metal-binding site
1267753012825	putative acetyltransferase; Provisional; Region: PRK03624
1267753012826	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753012827	Coenzyme A binding pocket [chemical binding]; other site
1267753012828	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
1267753012829	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
1267753012830	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
1267753012831	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
1267753012832	short chain dehydrogenase; Provisional; Region: PRK08226
1267753012833	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
1267753012834	NAD binding site [chemical binding]; other site
1267753012835	homotetramer interface [polypeptide binding]; other site
1267753012836	homodimer interface [polypeptide binding]; other site
1267753012837	active site
1267753012838	thiosulfate transporter subunit; Provisional; Region: PRK10852
1267753012839	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1267753012840	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1267753012841	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753012842	dimer interface [polypeptide binding]; other site
1267753012843	conserved gate region; other site
1267753012844	putative PBP binding loops; other site
1267753012845	ABC-ATPase subunit interface; other site
1267753012846	sulfate transport protein; Provisional; Region: cysT; CHL00187
1267753012847	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753012848	dimer interface [polypeptide binding]; other site
1267753012849	conserved gate region; other site
1267753012850	putative PBP binding loops; other site
1267753012851	ABC-ATPase subunit interface; other site
1267753012852	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
1267753012853	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1267753012854	Walker A/P-loop; other site
1267753012855	ATP binding site [chemical binding]; other site
1267753012856	Q-loop/lid; other site
1267753012857	ABC transporter signature motif; other site
1267753012858	Walker B; other site
1267753012859	D-loop; other site
1267753012860	H-loop/switch region; other site
1267753012861	TOBE-like domain; Region: TOBE_3; pfam12857
1267753012862	cysteine synthase B; Region: cysM; TIGR01138
1267753012863	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1267753012864	dimer interface [polypeptide binding]; other site
1267753012865	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753012866	catalytic residue [active]
1267753012867	hypothetical protein; Provisional; Region: PRK10318
1267753012868	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
1267753012869	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
1267753012870	catalytic triad [active]
1267753012871	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
1267753012872	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753012873	DNA-binding site [nucleotide binding]; DNA binding site
1267753012874	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753012875	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753012876	homodimer interface [polypeptide binding]; other site
1267753012877	catalytic residue [active]
1267753012878	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
1267753012879	dimer interface [polypeptide binding]; other site
1267753012880	pyridoxamine kinase; Validated; Region: PRK05756
1267753012881	pyridoxal binding site [chemical binding]; other site
1267753012882	ATP binding site [chemical binding]; other site
1267753012883	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1267753012884	HPr interaction site; other site
1267753012885	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1267753012886	active site
1267753012887	phosphorylation site [posttranslational modification]
1267753012888	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
1267753012889	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1267753012890	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1267753012891	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1267753012892	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1267753012893	dimerization domain swap beta strand [polypeptide binding]; other site
1267753012894	regulatory protein interface [polypeptide binding]; other site
1267753012895	active site
1267753012896	regulatory phosphorylation site [posttranslational modification]; other site
1267753012897	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1267753012898	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1267753012899	dimer interface [polypeptide binding]; other site
1267753012900	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753012901	catalytic residue [active]
1267753012902	putative sulfate transport protein CysZ; Validated; Region: PRK04949
1267753012903	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
1267753012904	cell division protein ZipA; Provisional; Region: PRK03427
1267753012905	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
1267753012906	FtsZ protein binding site [polypeptide binding]; other site
1267753012907	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1267753012908	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1267753012909	nucleotide binding pocket [chemical binding]; other site
1267753012910	K-X-D-G motif; other site
1267753012911	catalytic site [active]
1267753012912	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1267753012913	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1267753012914	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1267753012915	Dimer interface [polypeptide binding]; other site
1267753012916	BRCT sequence motif; other site
1267753012917	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
1267753012918	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
1267753012919	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
1267753012920	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1267753012921	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753012922	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
1267753012923	putative dimerization interface [polypeptide binding]; other site
1267753012924	hypothetical protein; Provisional; Region: PRK11528
1267753012925	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1267753012926	nucleoside transporter; Region: 2A0110; TIGR00889
1267753012927	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753012928	putative substrate translocation pore; other site
1267753012929	XapX domain; Region: XapX; TIGR03510
1267753012930	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
1267753012931	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753012932	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
1267753012933	putative dimerization interface [polypeptide binding]; other site
1267753012934	putative substrate binding pocket [chemical binding]; other site
1267753012935	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1267753012936	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1267753012937	active site
1267753012938	HIGH motif; other site
1267753012939	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1267753012940	active site
1267753012941	KMSKS motif; other site
1267753012942	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1267753012943	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
1267753012944	MASE1; Region: MASE1; pfam05231
1267753012945	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1267753012946	diguanylate cyclase; Region: GGDEF; smart00267
1267753012947	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1267753012948	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1267753012949	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1267753012950	Nucleoside recognition; Region: Gate; pfam07670
1267753012951	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1267753012952	manganese transport protein MntH; Reviewed; Region: PRK00701
1267753012953	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1267753012954	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
1267753012955	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1267753012956	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1267753012957	active site
1267753012958	catalytic tetrad [active]
1267753012959	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
1267753012960	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
1267753012961	dimer interface [polypeptide binding]; other site
1267753012962	PYR/PP interface [polypeptide binding]; other site
1267753012963	TPP binding site [chemical binding]; other site
1267753012964	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1267753012965	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
1267753012966	TPP-binding site [chemical binding]; other site
1267753012967	dimer interface [polypeptide binding]; other site
1267753012968	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1267753012969	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1267753012970	Cl- selectivity filter; other site
1267753012971	Cl- binding residues [ion binding]; other site
1267753012972	pore gating glutamate residue; other site
1267753012973	dimer interface [polypeptide binding]; other site
1267753012974	potential frameshift: common BLAST hit: gi|409251069|ref|YP_006886873.1| Glucokinase
1267753012975	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1267753012976	active site
1267753012977	P-loop; other site
1267753012978	phosphorylation site [posttranslational modification]
1267753012979	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1267753012980	aminopeptidase; Provisional; Region: PRK09795
1267753012981	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1267753012982	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1267753012983	active site
1267753012984	exoaminopeptidase; Provisional; Region: PRK09961
1267753012985	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
1267753012986	oligomer interface [polypeptide binding]; other site
1267753012987	active site
1267753012988	metal binding site [ion binding]; metal-binding site
1267753012989	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1267753012990	dimerization domain swap beta strand [polypeptide binding]; other site
1267753012991	regulatory protein interface [polypeptide binding]; other site
1267753012992	active site
1267753012993	regulatory phosphorylation site [posttranslational modification]; other site
1267753012994	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1267753012995	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1267753012996	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1267753012997	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1267753012998	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753012999	active site
1267753013000	phosphorylation site [posttranslational modification]
1267753013001	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1267753013002	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753013003	aminotransferase; Validated; Region: PRK08175
1267753013004	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753013005	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753013006	homodimer interface [polypeptide binding]; other site
1267753013007	catalytic residue [active]
1267753013008	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1267753013009	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1267753013010	putative acyl-acceptor binding pocket; other site
1267753013011	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
1267753013012	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
1267753013013	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753013014	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753013015	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1267753013016	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1267753013017	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
1267753013018	HAMP domain; Region: HAMP; pfam00672
1267753013019	dimerization interface [polypeptide binding]; other site
1267753013020	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753013021	dimer interface [polypeptide binding]; other site
1267753013022	phosphorylation site [posttranslational modification]
1267753013023	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753013024	ATP binding site [chemical binding]; other site
1267753013025	Mg2+ binding site [ion binding]; other site
1267753013026	G-X-G motif; other site
1267753013027	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1267753013028	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753013029	active site
1267753013030	phosphorylation site [posttranslational modification]
1267753013031	intermolecular recognition site; other site
1267753013032	dimerization interface [polypeptide binding]; other site
1267753013033	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1267753013034	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1267753013035	outer membrane protease; Reviewed; Region: PRK10993
1267753013036	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
1267753013037	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
1267753013038	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
1267753013039	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
1267753013040	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
1267753013041	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1267753013042	dimer interface [polypeptide binding]; other site
1267753013043	active site
1267753013044	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
1267753013045	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1267753013046	substrate binding site [chemical binding]; other site
1267753013047	oxyanion hole (OAH) forming residues; other site
1267753013048	trimer interface [polypeptide binding]; other site
1267753013049	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1267753013050	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1267753013051	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1267753013052	catalytic core [active]
1267753013053	hypothetical protein; Provisional; Region: PRK04946
1267753013054	Smr domain; Region: Smr; pfam01713
1267753013055	HemK family putative methylases; Region: hemK_fam; TIGR00536
1267753013056	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753013057	S-adenosylmethionine binding site [chemical binding]; other site
1267753013058	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1267753013059	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1267753013060	Tetramer interface [polypeptide binding]; other site
1267753013061	active site
1267753013062	FMN-binding site [chemical binding]; other site
1267753013063	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
1267753013064	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
1267753013065	hypothetical protein; Provisional; Region: PRK10621
1267753013066	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1267753013067	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
1267753013068	YfcL protein; Region: YfcL; pfam08891
1267753013069	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1267753013070	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1267753013071	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1267753013072	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
1267753013073	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1267753013074	dimer interface [polypeptide binding]; other site
1267753013075	active site
1267753013076	CAAX protease self-immunity; Region: Abi; pfam02517
1267753013077	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
1267753013078	putative transporter; Provisional; Region: PRK12382
1267753013079	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753013080	putative substrate translocation pore; other site
1267753013081	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
1267753013082	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
1267753013083	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
1267753013084	ligand binding site [chemical binding]; other site
1267753013085	NAD binding site [chemical binding]; other site
1267753013086	catalytic site [active]
1267753013087	homodimer interface [polypeptide binding]; other site
1267753013088	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
1267753013089	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1267753013090	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
1267753013091	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1267753013092	dimerization interface 3.5A [polypeptide binding]; other site
1267753013093	active site
1267753013094	hypothetical protein; Provisional; Region: PRK10847
1267753013095	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1267753013096	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1267753013097	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1267753013098	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
1267753013099	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1267753013100	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1267753013101	cell division protein DedD; Provisional; Region: PRK11633
1267753013102	Sporulation related domain; Region: SPOR; pfam05036
1267753013103	colicin V production protein; Provisional; Region: PRK10845
1267753013104	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1267753013105	amidophosphoribosyltransferase; Provisional; Region: PRK09246
1267753013106	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1267753013107	active site
1267753013108	tetramer interface [polypeptide binding]; other site
1267753013109	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1267753013110	active site
1267753013111	PAS fold; Region: PAS_4; pfam08448
1267753013112	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1267753013113	putative active site [active]
1267753013114	heme pocket [chemical binding]; other site
1267753013115	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1267753013116	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1267753013117	Walker A motif; other site
1267753013118	ATP binding site [chemical binding]; other site
1267753013119	Walker B motif; other site
1267753013120	arginine finger; other site
1267753013121	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1267753013122	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1267753013123	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1267753013124	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1267753013125	catalytic residue [active]
1267753013126	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
1267753013127	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
1267753013128	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
1267753013129	dimer interface [polypeptide binding]; other site
1267753013130	active site
1267753013131	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1267753013132	substrate binding site [chemical binding]; other site
1267753013133	catalytic residue [active]
1267753013134	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1267753013135	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1267753013136	Flavoprotein; Region: Flavoprotein; pfam02441
1267753013137	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
1267753013138	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753013139	substrate binding pocket [chemical binding]; other site
1267753013140	membrane-bound complex binding site; other site
1267753013141	hinge residues; other site
1267753013142	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
1267753013143	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1267753013144	substrate binding pocket [chemical binding]; other site
1267753013145	membrane-bound complex binding site; other site
1267753013146	hinge residues; other site
1267753013147	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1267753013148	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753013149	dimer interface [polypeptide binding]; other site
1267753013150	conserved gate region; other site
1267753013151	putative PBP binding loops; other site
1267753013152	ABC-ATPase subunit interface; other site
1267753013153	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1267753013154	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1267753013155	dimer interface [polypeptide binding]; other site
1267753013156	conserved gate region; other site
1267753013157	putative PBP binding loops; other site
1267753013158	ABC-ATPase subunit interface; other site
1267753013159	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
1267753013160	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1267753013161	Walker A/P-loop; other site
1267753013162	ATP binding site [chemical binding]; other site
1267753013163	Q-loop/lid; other site
1267753013164	ABC transporter signature motif; other site
1267753013165	Walker B; other site
1267753013166	D-loop; other site
1267753013167	H-loop/switch region; other site
1267753013168	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1267753013169	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1267753013170	putative NAD(P) binding site [chemical binding]; other site
1267753013171	putative active site [active]
1267753013172	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
1267753013173	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
1267753013174	C-terminal domain interface [polypeptide binding]; other site
1267753013175	GSH binding site (G-site) [chemical binding]; other site
1267753013176	dimer interface [polypeptide binding]; other site
1267753013177	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
1267753013178	N-terminal domain interface [polypeptide binding]; other site
1267753013179	putative dimer interface [polypeptide binding]; other site
1267753013180	active site
1267753013181	glutathione S-transferase; Provisional; Region: PRK15113
1267753013182	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
1267753013183	C-terminal domain interface [polypeptide binding]; other site
1267753013184	GSH binding site (G-site) [chemical binding]; other site
1267753013185	dimer interface [polypeptide binding]; other site
1267753013186	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
1267753013187	N-terminal domain interface [polypeptide binding]; other site
1267753013188	putative dimer interface [polypeptide binding]; other site
1267753013189	putative substrate binding pocket (H-site) [chemical binding]; other site
1267753013190	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1267753013191	active site
1267753013192	metal binding site [ion binding]; metal-binding site
1267753013193	homotetramer interface [polypeptide binding]; other site
1267753013194	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
1267753013195	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
1267753013196	nudix motif; other site
1267753013197	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1267753013198	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1267753013199	DNA binding site [nucleotide binding]
1267753013200	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
1267753013201	putative dimerization interface [polypeptide binding]; other site
1267753013202	putative ligand binding site [chemical binding]; other site
1267753013203	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1267753013204	active site
1267753013205	phosphorylation site [posttranslational modification]
1267753013206	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1267753013207	active site
1267753013208	P-loop; other site
1267753013209	phosphorylation site [posttranslational modification]
1267753013210	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
1267753013211	transketolase; Reviewed; Region: PRK05899
1267753013212	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1267753013213	TPP-binding site [chemical binding]; other site
1267753013214	dimer interface [polypeptide binding]; other site
1267753013215	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1267753013216	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1267753013217	PYR/PP interface [polypeptide binding]; other site
1267753013218	dimer interface [polypeptide binding]; other site
1267753013219	TPP binding site [chemical binding]; other site
1267753013220	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1267753013221	hypothetical protein; Provisional; Region: PRK11588
1267753013222	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1267753013223	phosphate acetyltransferase; Reviewed; Region: PRK05632
1267753013224	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1267753013225	DRTGG domain; Region: DRTGG; pfam07085
1267753013226	phosphate acetyltransferase; Region: pta; TIGR00651
1267753013227	propionate/acetate kinase; Provisional; Region: PRK12379
1267753013228	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1267753013229	hypothetical protein; Provisional; Region: PRK01816
1267753013230	hypothetical protein; Validated; Region: PRK05445
1267753013231	putative phosphatase; Provisional; Region: PRK11587
1267753013232	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1267753013233	motif II; other site
1267753013234	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1267753013235	transmembrane helices; other site
1267753013236	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1267753013237	TrkA-C domain; Region: TrkA_C; pfam02080
1267753013238	TrkA-C domain; Region: TrkA_C; pfam02080
1267753013239	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
1267753013240	5'-nucleotidase; Provisional; Region: PRK03826
1267753013241	aminotransferase AlaT; Validated; Region: PRK09265
1267753013242	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1267753013243	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753013244	homodimer interface [polypeptide binding]; other site
1267753013245	catalytic residue [active]
1267753013246	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
1267753013247	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753013248	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
1267753013249	putative dimerization interface [polypeptide binding]; other site
1267753013250	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1267753013251	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
1267753013252	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
1267753013253	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1267753013254	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1267753013255	NADH dehydrogenase subunit E; Validated; Region: PRK07539
1267753013256	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1267753013257	putative dimer interface [polypeptide binding]; other site
1267753013258	[2Fe-2S] cluster binding site [ion binding]; other site
1267753013259	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
1267753013260	SLBB domain; Region: SLBB; pfam10531
1267753013261	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1267753013262	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
1267753013263	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1267753013264	catalytic loop [active]
1267753013265	iron binding site [ion binding]; other site
1267753013266	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1267753013267	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
1267753013268	[4Fe-4S] binding site [ion binding]; other site
1267753013269	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
1267753013270	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1267753013271	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1267753013272	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753013273	4Fe-4S binding domain; Region: Fer4; pfam00037
1267753013274	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1267753013275	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1267753013276	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1267753013277	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1267753013278	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1267753013279	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1267753013280	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1267753013281	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1267753013282	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1267753013283	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1267753013284	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1267753013285	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1267753013286	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753013287	active site
1267753013288	phosphorylation site [posttranslational modification]
1267753013289	intermolecular recognition site; other site
1267753013290	dimerization interface [polypeptide binding]; other site
1267753013291	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1267753013292	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1267753013293	Coenzyme A binding pocket [chemical binding]; other site
1267753013294	hypothetical protein; Provisional; Region: PRK10404
1267753013295	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
1267753013296	isochorismate synthases; Region: isochor_syn; TIGR00543
1267753013297	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1267753013298	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1267753013299	dimer interface [polypeptide binding]; other site
1267753013300	tetramer interface [polypeptide binding]; other site
1267753013301	PYR/PP interface [polypeptide binding]; other site
1267753013302	TPP binding site [chemical binding]; other site
1267753013303	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1267753013304	TPP-binding site; other site
1267753013305	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
1267753013306	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1267753013307	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1267753013308	substrate binding site [chemical binding]; other site
1267753013309	oxyanion hole (OAH) forming residues; other site
1267753013310	trimer interface [polypeptide binding]; other site
1267753013311	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
1267753013312	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1267753013313	active site
1267753013314	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
1267753013315	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1267753013316	acyl-activating enzyme (AAE) consensus motif; other site
1267753013317	putative AMP binding site [chemical binding]; other site
1267753013318	putative active site [active]
1267753013319	putative CoA binding site [chemical binding]; other site
1267753013320	signal transduction protein PmrD; Provisional; Region: PRK15450
1267753013321	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
1267753013322	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
1267753013323	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
1267753013324	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
1267753013325	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
1267753013326	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
1267753013327	putative active site [active]
1267753013328	putative catalytic site [active]
1267753013329	putative Zn binding site [ion binding]; other site
1267753013330	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
1267753013331	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1267753013332	active site
1267753013333	substrate binding site [chemical binding]; other site
1267753013334	cosubstrate binding site; other site
1267753013335	catalytic site [active]
1267753013336	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
1267753013337	active site
1267753013338	hexamer interface [polypeptide binding]; other site
1267753013339	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1267753013340	NAD binding site [chemical binding]; other site
1267753013341	substrate binding site [chemical binding]; other site
1267753013342	active site
1267753013343	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1267753013344	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1267753013345	Ligand binding site; other site
1267753013346	Putative Catalytic site; other site
1267753013347	DXD motif; other site
1267753013348	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1267753013349	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1267753013350	inhibitor-cofactor binding pocket; inhibition site
1267753013351	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1267753013352	catalytic residue [active]
1267753013353	potential frameshift: common BLAST hit: gi|194442758|ref|YP_002041557.1| Ais protein
1267753013354	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
1267753013355	YfaZ precursor; Region: YfaZ; pfam07437
1267753013356	hypothetical protein; Provisional; Region: PRK03673
1267753013357	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1267753013358	putative MPT binding site; other site
1267753013359	Competence-damaged protein; Region: CinA; cl00666
1267753013360	deubiquitinase SseL; Provisional; Region: PRK14848
1267753013361	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
1267753013362	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1267753013363	Cysteine-rich domain; Region: CCG; pfam02754
1267753013364	Cysteine-rich domain; Region: CCG; pfam02754
1267753013365	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
1267753013366	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
1267753013367	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
1267753013368	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1267753013369	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1267753013370	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
1267753013371	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753013372	putative substrate translocation pore; other site
1267753013373	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
1267753013374	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
1267753013375	active site
1267753013376	catalytic site [active]
1267753013377	metal binding site [ion binding]; metal-binding site
1267753013378	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
1267753013379	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1267753013380	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1267753013381	dimerization interface [polypeptide binding]; other site
1267753013382	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1267753013383	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753013384	putative substrate translocation pore; other site
1267753013385	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1267753013386	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1267753013387	catalytic loop [active]
1267753013388	iron binding site [ion binding]; other site
1267753013389	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1267753013390	dimer interface [polypeptide binding]; other site
1267753013391	putative radical transfer pathway; other site
1267753013392	diiron center [ion binding]; other site
1267753013393	tyrosyl radical; other site
1267753013394	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
1267753013395	ATP cone domain; Region: ATP-cone; pfam03477
1267753013396	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1267753013397	active site
1267753013398	dimer interface [polypeptide binding]; other site
1267753013399	catalytic residues [active]
1267753013400	effector binding site; other site
1267753013401	R2 peptide binding site; other site
1267753013402	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
1267753013403	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1267753013404	S-adenosylmethionine binding site [chemical binding]; other site
1267753013405	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1267753013406	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1267753013407	DNA-binding site [nucleotide binding]; DNA binding site
1267753013408	FCD domain; Region: FCD; pfam07729
1267753013409	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
1267753013410	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1267753013411	putative substrate translocation pore; other site
1267753013412	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1267753013413	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
1267753013414	active site pocket [active]
1267753013415	phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396
1267753013416	DNA gyrase subunit A; Validated; Region: PRK05560
1267753013417	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1267753013418	CAP-like domain; other site
1267753013419	active site
1267753013420	primary dimer interface [polypeptide binding]; other site
1267753013421	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1267753013422	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1267753013423	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1267753013424	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1267753013425	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1267753013426	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1267753013427	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
1267753013428	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1267753013429	dimer interface [polypeptide binding]; other site
1267753013430	phosphorylation site [posttranslational modification]
1267753013431	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753013432	ATP binding site [chemical binding]; other site
1267753013433	Mg2+ binding site [ion binding]; other site
1267753013434	G-X-G motif; other site
1267753013435	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
1267753013436	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753013437	active site
1267753013438	phosphorylation site [posttranslational modification]
1267753013439	intermolecular recognition site; other site
1267753013440	dimerization interface [polypeptide binding]; other site
1267753013441	transcriptional regulator RcsB; Provisional; Region: PRK10840
1267753013442	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1267753013443	active site
1267753013444	phosphorylation site [posttranslational modification]
1267753013445	intermolecular recognition site; other site
1267753013446	dimerization interface [polypeptide binding]; other site
1267753013447	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1267753013448	DNA binding residues [nucleotide binding]
1267753013449	dimerization interface [polypeptide binding]; other site
1267753013450	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
1267753013451	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1267753013452	ATP binding site [chemical binding]; other site
1267753013453	G-X-G motif; other site
1267753013454	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1267753013455	putative binding surface; other site
1267753013456	active site
1267753013457	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
1267753013458	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
1267753013459	trimer interface [polypeptide binding]; other site
1267753013460	eyelet of channel; other site
1267753013461	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
1267753013462	ApbE family; Region: ApbE; pfam02424
1267753013463	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
1267753013464	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1267753013465	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1267753013466	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
1267753013467	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1267753013468	DNA binding site [nucleotide binding]
1267753013469	active site
1267753013470	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
1267753013471	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
1267753013472	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1267753013473	Walker A/P-loop; other site
1267753013474	ATP binding site [chemical binding]; other site
1267753013475	Q-loop/lid; other site
1267753013476	ABC transporter signature motif; other site
1267753013477	Walker B; other site
1267753013478	D-loop; other site
1267753013479	H-loop/switch region; other site
1267753013480	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
1267753013481	secondary substrate binding site; other site
1267753013482	primary substrate binding site; other site
1267753013483	inhibition loop; other site
1267753013484	dimerization interface [polypeptide binding]; other site
1267753013485	ferredoxin-type protein; Provisional; Region: PRK10194
1267753013486	4Fe-4S binding domain; Region: Fer4; cl02805
1267753013487	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
1267753013488	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1267753013489	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
1267753013490	[4Fe-4S] binding site [ion binding]; other site
1267753013491	molybdopterin cofactor binding site; other site
1267753013492	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1267753013493	molybdopterin cofactor binding site; other site
1267753013494	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1267753013495	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1267753013496	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1267753013497	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1267753013498	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
1267753013499	cytochrome c-type protein NapC; Provisional; Region: PRK10617
1267753013500	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1267753013501	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
1267753013502	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1267753013503	Walker A/P-loop; other site
1267753013504	ATP binding site [chemical binding]; other site
1267753013505	Q-loop/lid; other site
1267753013506	ABC transporter signature motif; other site
1267753013507	Walker B; other site
1267753013508	D-loop; other site
1267753013509	H-loop/switch region; other site
1267753013510	heme exporter protein CcmB; Region: ccmB; TIGR01190
1267753013511	heme exporter protein CcmC; Region: ccmC; TIGR01191
1267753013512	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
1267753013513	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
1267753013514	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1267753013515	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1267753013516	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1267753013517	P-loop; other site
1267753013518	Magnesium ion binding site [ion binding]; other site
1267753013519	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1267753013520	Magnesium ion binding site [ion binding]; other site
1267753013521	Abi-like protein; Region: Abi_2; pfam07751
1267753013522	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1267753013523	Serine recombinase (SR) family, Partitioning (par)-Resolvase subfamily, catalytic domain; Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient...; Region: SR_Res_par; cd03767
1267753013524	catalytic residues [active]
1267753013525	catalytic nucleophile [active]
1267753013526	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cl17402
1267753013527	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
1267753013528	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
1267753013529	Integrase core domain; Region: rve; pfam00665
1267753013530	fimbrial chaperone protein PefD; Provisional; Region: PRK15211
1267753013531	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
1267753013532	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
1267753013533	fimbrial outer membrane usher protein PefC; Provisional; Region: PRK15213
1267753013534	PapC N-terminal domain; Region: PapC_N; pfam13954
1267753013535	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
1267753013536	fimbrial protein PefA; Provisional; Region: PRK15214
1267753013537	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1267753013538	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1267753013539	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
1267753013540	active site
1267753013541	catalytic residues [active]
1267753013542	DNA binding site [nucleotide binding]
1267753013543	Int/Topo IB signature motif; other site
1267753013544	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
1267753013545	plasmid maintenance protein CcdA; Provisional; Region: PRK13710